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Comparison of outcomes of Foley's induced labors with different sonographic floater densities in fore-water 不同声像图水中漂浮物密度对Foley引产效果的比较
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_111_19
S. Hemmanur, Sai Illa, Hanuman Krishna
Background: Onset of spontaneous labor occurs on completion of fetal functional maturity at amniotic fluid optical density (AFOD) 0.98 ± 0.27 (mean ± SD). All three events occurring together at any time from 35 weeks to 42 weeks indicate the individualized term for each fetus. No failures of induction of labor were reported when labors induced at AFOD 0.98 ± 0.27. As AFOD estimation needs invasive amniocentesis, we tried to induce women with liquor with mature AFOD by observing the sonographic appearances of fore-water by transvaginal sonography. Methods: In this comparative study, three groups of gestational age and parity matched uncomplicated singleton term pregnant women, underwent fore-water trans-vaginal sonography before induction of labor with Foley's catheter. Sonographic images were divided into three grades based on floating particle densities. Each group consisted of 20 women with each grade of sonographic images. Uncentrifuged fresh AF samples collected at amniotomy were used for AFOD measurement with colorimeter at 650 nm in all groups. After Foley's expulsion, labor was augmented with vaginal misoprostol. The mean AFOD values, Foley's insertion expulsion intervals, Foley's insertion delivery intervals (FIDI), T misoprostol required, and neonatal respiratory distress were recorded in each group and compared. Results: In groups 1, 2, and 3, the mean AFOD was found to be 0.29 ± 0.09, 0.68 ± 0.14, and 1.15 ± 0.20, respectively. Mean Foley's insertion expulsion intervals were 10.57 ± 3.76 h, 5.83 ± 2.24 h, and 4.08 ± 0.86 h, respectively. Mean FIDI were 20.00 ± 6.20 h, 11.22 ± 4.20 h, and 8.95 ± 2.98 h, respectively. The mean numbers of T misoprostol required in each group was 3 ± 1, 2 ± 1, and 2 ± 1, respectively. Significant differences were observed in all outcomes between groups (P < 0.05) favouring inductions with Grade 3 sonographic images. Conclusion: Labor induction with Grade 3 sonographic images of fore-water was successful in all women with shorter FIDI, and with better perinatal outcomes.
背景:羊水光密度(AFOD)为0.98±0.27(平均值±SD),胎儿功能成熟时发生自然分娩。这三种情况同时发生在35周至42周的任何时间,表明每个胎儿的个体化足月。当AFOD值为0.98±0.27时,无引产失败报告。由于AFOD的判断需要有创羊膜穿刺术,我们尝试通过阴道超声观察前水的声像图表现来诱导成熟的AFOD女性。方法:在本比较研究中,三组胎龄和胎次匹配的无并发症单胎足月孕妇,在使用Foley导尿管引产前行水前阴道超声检查。根据浮动粒子密度将超声图像分为三个等级。每组20名妇女,超声图像各分级。各组取羊膜切开时未离心的新鲜心房纤颤标本,用比色计在650 nm处测定心房纤颤度。Foley排出后,阴道使用米索前列醇增加产程。记录各组平均AFOD值、Foley插入排出间隔时间、Foley插入分娩间隔时间(FIDI)、需要量T米索前列醇、新生儿呼吸窘迫情况并进行比较。结果:1、2、3组平均AFOD分别为0.29±0.09、0.68±0.14、1.15±0.20。平均Foley插入排出间隔分别为10.57±3.76 h、5.83±2.24 h和4.08±0.86 h。平均FIDI分别为20.00±6.20 h、11.22±4.20 h和8.95±2.98 h。各组患者所需T米索前列醇平均剂量分别为3±1、2±1和2±1。超声显像为3级诱导的组间各项指标差异均有统计学意义(P < 0.05)。结论:所有FIDI较短的妇女采用前水3级超声显像引产均成功,围产儿结局较好。
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引用次数: 1
A double-blind randomized controlled clinical trial of oral misoprostol versus ergometrine in the prevention of primary postpartum hemorrhage 口服米索前列醇与麦角新碱预防原发性产后出血的双盲随机对照临床试验
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_52_19
V. Otoide
Objective: The study was designed to investigate the effectiveness of orally administered misoprostol versus intravenous ergometrine (stored at tropical temperatures) in the prevention of primary postpartum hemorrhage (PPH) among parturients undergoing vaginal delivery in a teaching hospital. Study Design: A double-blind randomized controlled clinical trial was conducted at the University of Benin Teaching Hospital. One hundred and fifty parturients were offered 400 ug misoprostol and an intravenous placebo for the management of the third stage of labor while another 150 parturients received oral placebo and 0.5 mg intravenous ergometrine. Results: There was no significant difference in the incidence of PPH (blood loss > 500 ml) between the two groups: 8 (5.3%) for the misoprostol group compared with 7 (4.7%) for the ergometrine group (P = 0.79, relative risk (RR) = 1.07, confidence interval (CI): 0.66–1.74). The incidence of severe PPH (blood loss > 1000 ml) was similar between the two groups: 2 (1.3%) in the misoprostol group compared with 1 (0.7%) in the ergometrine group. Similarly, the indices of postpartum blood loss (hematocrit change, need for blood transfusion, and surgical intervention) were comparable between the two groups. A subgroup analysis of high-risk parturients revealed comparable indices. The misoprostol group, however, had a significantly higher risk of shivering in the early postpartum period (P = 0.00, RR = 2.01, CI: 1.69–2.38). Conclusions: The results suggest that oral misoprostol has comparable efficacy to intravenous ergometrine at tropical conditions in the prevention of PPH. However, in view of its easier mode of administration, oral misoprostol may be preferable in rural situations in Africa.
目的:本研究旨在研究米索前列醇与麦角新碱(在热带温度下储存)在教学医院阴道分娩产妇中预防原发性产后出血(PPH)的有效性。研究设计:在贝宁大学教学医院进行了一项双盲随机对照临床试验。150名产妇接受了400 ug米索前列醇和静脉注射安慰剂用于第三产程的管理,另有150名产妇则接受了口服安慰剂和0.5 mg静脉注射麦角新碱。结果:两组PPH(失血量>500ml)的发生率无显著差异:米索前列醇组8例(5.3%)与麦角新碱组7例(4.7%)(P=0.79、相对危险度(RR)=1.07,置信区间(CI):0.66-1.74)。两组之间严重PPH(失血>1000 ml)的发生率相似:米索前列醇组为2例(1.3%),而麦角新碱组为1例(0.7%)。同样,两组产后失血指标(红细胞压积变化、输血需求和手术干预)具有可比性。高危产妇的亚组分析显示了可比较的指标。然而,米索前列醇组在产后早期发生颤抖的风险明显更高(P=0.00,RR=2.01,CI:1.69-2.38)。然而,鉴于口服米索前列醇的给药方式更容易,在非洲的农村地区可能更可取。
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引用次数: 0
Planned cesarean myomectomy at term for huge intramural fibroids coexisting with pregnancy: A case report 足月计划剖宫产子宫肌瘤切除术治疗合并妊娠的巨大肌壁内肌瘤1例
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_70_19
O. Adeniyi, O. Olayemi, T. Ojumu, S. Olateju, O. Makinde
With about 2–11% of pregnancy co-existing with fibroids, one in 10 women will have complications related to myoma in pregnancy. The procedure of cesarean myomectomy has been much discouraged and the need to perform inevitable myomectomy during the cesarean section (CS) when fibroids obstruct wound closure has been presented. A case of a primigravida with huge uterine fibroids displacing the fetus into a persistent oblique lie and causing maternal discomfort is presented. A planned cesarean myomectomy was performed. Hemorrhage was controlled with tourniquet using Foley catheter, misoprostol, and high dose oxytocin infusion. The mother and baby had a satisfactory outcome. Elective cesarean myomectomy is safe but should only be done by an experienced surgeon and in centers equipped with facilities for comprehensive emergency obstetric care.
约有2-11%的妊娠合并子宫肌瘤,十分之一的女性在妊娠期间会出现与肌瘤相关的并发症。剖宫产子宫肌瘤切除术一直不受欢迎,当肌瘤阻碍伤口闭合时,需要在剖宫产(CS)期间进行不可避免的子宫肌瘤切除。报告了一例患有巨大子宫肌瘤的初产妇,使胎儿持续斜卧,并引起产妇不适。进行了计划中的剖宫产子宫肌瘤切除术。使用Foley导管止血带、米索前列醇和大剂量催产素输注控制出血。母亲和婴儿的结局令人满意。选择性剖宫产子宫肌瘤切除术是安全的,但只能由经验丰富的外科医生和配备全面产科急诊设施的中心进行。
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引用次数: 0
Improving undergraduate medical education in Nigeria: Insight into the past 改善尼日利亚的本科医学教育:回顾过去
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_62_19
A. Omigbodun
The first three in the series of Society of Gynaecology and Obstetrics of Nigeria (SOGON) lectures on “Frontiers in Medical Education,” in honor of Professor Linus Ajabor, had focused on internship and postgraduate medical education. This fourth lecture is about the evolution of undergraduate medical education in Nigeria from its rudimentary beginning in 1930 to the present. Lessons from the past include the desirability of tailoring medical education toward meeting national needs, doing proper needs assessment before planning and implementation, setting minimum standards for training institutions, and enforcing these standards through a credible process of accreditation. Recommendations for the future include a harmonization of the guidelines on minimum standards published by the Medical and Dental Council of Nigeria (MDCN) and the minimum academic standards published by Nigeria's National Universities Commission (NUC), and the conduct of joint accreditation by both agencies to maximize efficiency and reduce waste. There should also be mandatory training in pedagogy for clinician teachers, periodic curriculum reviews must be enforced, and simulation laboratories should be provided in all accredited medical schools.
尼日利亚妇产科学会(SOGON)为纪念Linus Ajabor教授而举办的“医学教育前沿”系列讲座的前三期重点是实习和研究生医学教育。第四讲是关于尼日利亚本科医学教育从1930年的初级阶段到现在的演变。过去的经验教训包括,有必要调整医学教育以满足国家需求,在规划和实施之前进行适当的需求评估,为培训机构制定最低标准,并通过可信的认证程序执行这些标准。未来的建议包括统一尼日利亚医学和牙科委员会(MDCN)发布的最低标准指南和尼日利亚国家大学委员会(NUC)发布的最高学术标准,以及由两个机构进行联合认证,以最大限度地提高效率和减少浪费。临床医生教师还应接受教育学方面的强制性培训,必须定期进行课程审查,所有经认证的医学院都应提供模拟实验室。
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引用次数: 0
Ovarian cancer: An undertreated and understudied entity in sub Saharan Africa 卵巢癌症:撒哈拉以南非洲治疗不足和研究不足的实体
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_28_20
A. Akinfolarin
Ovarian cancer (OC) is currently the 7th most common malignancy globally and the most lethal gynecological cancer.[1] It has been estimated that, in the United States, one woman in 70 will develop ovarian cancer, and one woman in 100 will die of the disease.[2] Ovarian cancer rates vary between different countries and appear to be related to socioeconomic status and reproductive factors. It is the second most common gynaecological cancer in sub Saharan Africa. Epithelial ovarian cancer (EOC) constitutes about 85-90% of all ovarian malignancies.[1] In both developed and developing nations, the case fatality of ovarian cancer is very high for some reasons. The disease is associated with late presentation as there are no specific early symptoms to warn the patients and caregivers, there are no significant screening tests to predict patients who might develop the cancer and no matter how good the immediate outcomes following the current standard modalities of treatment which includes optimum debulking surgery and chemotherapy, recurrence is the rule rather than the exception in most cases.
癌症(OC)是目前全球第七大最常见的恶性肿瘤,也是最致命的妇科癌症。[1] 据估计,在美国,每70名女性中就有一人会患上卵巢癌症,每100名女性中就会有一人死于这种疾病。[2] 不同国家的卵巢癌症发病率不同,似乎与社会经济地位和生殖因素有关。它是撒哈拉以南非洲第二常见的妇科癌症。上皮性癌症(EOC)约占所有卵巢恶性肿瘤的85-90%。[1] 在发达国家和发展中国家,由于某些原因,卵巢癌症的病死率都很高。该疾病与晚期表现有关,因为没有具体的早期症状来警告患者和护理人员,没有重要的筛查测试来预测可能发展为癌症的患者,无论目前的标准治疗模式(包括最佳减瘤手术和化疗)的近期效果如何,在大多数情况下,复发是规律而非例外。
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引用次数: 1
Surgical management of uterine fibroids in a tertiary hospital in south-west Nigeria 尼日利亚西南部一家三级医院子宫肌瘤的外科治疗
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_49_19
O. Enabor, F. Bello
Context: Symptomatic uterine fibroids are frequently encountered in gynecological practice in black populations. An evaluation of the surgical management is in order to audit practice, highlight complications, and facilitate care. Aims: This study aimed to evaluate morbidity following abdominal myomectomy and hysterectomy for symptomatic uterine fibroids. Settings and Design: A cross-sectional study retrospectively reviewing cases of symptomatic uterine fibroids that were managed surgically at a tertiary hospital in south-west Nigeria. Methods and Material: Surgeries performed over a five-year period were retrieved from the gynecological theatre of the hospital. The case notes were retrieved and information on socio-demographic, perioperative and postoperative characteristics was obtained. Statistical analysis used: Chi-square tests and Student's-t tests were performed to evaluate categorical and continuous variables, respectively. Significant P was set at < 0.05. Results: Of 214 eligible cases, 79 (36.9%) had hysterectomy and 135 (63.1%) had myomectomy. No other surgical treatment methods were employed. Age was the only significant socio-demographic feature; younger women were more likely to have myomectomy (P < 0.001). Mean blood loss and transfusion rates were comparable between the two groups. Complications included hemorrhage in 36.0%, wound infection in 4.7%, and postoperative fever in 1.9%. There were no conversions of myomectomy to hysterectomy and no mortalities. There was no significant difference in the prevalence of complications in either surgery group. Conclusions: Apart from hemorrhage, morbidities were few in this series. Gynecologists should ensure adequate preparations to control blood loss before and during fibroid surgery.
背景:症状性子宫肌瘤在黑人人群的妇科实践中经常遇到。评估手术管理是为了审计实践,突出并发症,促进护理。目的:本研究旨在评估症状性子宫肌瘤切除术和子宫切除术后的发病率。背景和设计:一项横断面研究回顾性回顾了尼日利亚西南部一家三级医院手术治疗的症状性子宫肌瘤病例。方法和材料:从该院妇科手术室检索5年以上手术病例。检索病例记录,并获得社会人口统计学信息,围手术期和术后特征。采用统计分析:分别采用卡方检验和Student's-t检验对分类变量和连续变量进行评价。P < 0.05。结果:214例患者中,79例(36.9%)行子宫切除术,135例(63.1%)行子宫肌瘤切除术。未采用其他手术治疗方法。年龄是唯一重要的社会人口特征;年轻女性更有可能进行子宫肌瘤切除术(P < 0.001)。两组的平均失血量和输血率相当。并发症包括出血36.0%,伤口感染4.7%,术后发热1.9%。没有子宫肌瘤切除术转为子宫切除术,也没有死亡。两组的并发症发生率无显著差异。结论:除出血外,本组病例发病率较低。妇科医生应确保在子宫肌瘤手术前和手术中做好充分的准备,以控制失血。
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引用次数: 1
Triglycerides and TG/HDL-C ratio as surrogate markers for insulin resistance in Nigerian women with polycystic ovary syndrome 甘油三酯和TG/HDL-C比值作为尼日利亚多囊卵巢综合征妇女胰岛素抵抗的替代指标
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_104_19
C. Akpata, P. Uadia, F. Okonofua
Background: Dyslipidemia is one of the most perplexing metabolic consequences in polycystic ovary syndrome (PCOS). Obesity, insulin resistance (IR), and hyperandrogenism, the pervasive features of PCOS, play significant pathophysiological roles in the lipidemic aberrations associated with the syndrome. Objective: This study aimed to assess the diagnostic utility of triglyceride (TG) and triglyceride to high-density lipoprotein-cholesterol (TG/HDL-C) ratio as surrogate markers for identifying IR in infertile Nigerian women with PCOS. Materials and Methods: Eighty-seven infertile women with PCOS were selected according to the Androgen Excess Society criteria and categorized into two groups. After anthropometric measurements, fasting blood samples were assayed for plasma glucose, serum insulin, total cholesterol, TG, HDL-C while lipoprotein ratios were calculated. Homeostasis model assessment for IR (HOMA-IR) was used in defining IR. The areas under the receiver operating characteristic (ROC) curve analysis were used to compare the power of the serum markers, and to obtain the optimal cutoffs of TG and TG/HDL-C with HOMA-IR. Results: TGs correlated significantly with HOMA-IR in the obese PCOS women. However, the areas under the ROC of potential markers showed no significant marker for HOMA-IR. The highest area under the curve of ROC for TG belongs to the obese group with a sensitivity of 56% and specificity of 53% (TG ≥ 92.5mg/dL) as a marker of IR in obese PCOS women. Conclusion: TG and TG/HDL-C would not be reliable markers of IR, and a concerted approach in finding surrogate markers will benefit future investigations.
背景:血脂异常是多囊卵巢综合征(PCOS)最令人困惑的代谢后果之一。肥胖、胰岛素抵抗(IR)和高雄激素血症是多囊卵巢综合征的普遍特征,在与该综合征相关的血脂异常中发挥着重要的病理生理作用。目的:本研究旨在评估甘油三酯(TG)和甘油三酯与高密度脂蛋白胆固醇(TG/HDL-C)比值作为替代指标对尼日利亚不孕PCOS妇女IR的诊断价值。材料和方法:根据雄激素过量社会标准,选择87例多囊卵巢综合征不孕妇女,分为两组。人体测量后,测定空腹血样的血糖、血清胰岛素、总胆固醇、TG、HDL-C,同时计算脂蛋白比率。IR稳态模型评估(HOMA-IR)用于定义IR。受试者工作特性(ROC)曲线下面积分析用于比较血清标志物的功率,并通过HOMA-IR获得TG和TG/HDL-C的最佳临界值。结果:肥胖PCOS妇女的TGs与HOMA-IR显著相关。然而,潜在标记的ROC下区域没有显示HOMA-IR的显著标记。TG ROC曲线下最高面积属于肥胖组,作为肥胖PCOS女性IR的标志物,其敏感性为56%,特异性为53%(TG≥92.5mg/dL)。结论:TG和TG/HDL-C不是IR的可靠标志物,寻找替代标志物的协同方法将有利于未来的研究。
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引用次数: 0
Erratum: Office cystometry in a resource-constrained setting: Spectrum of diagnoses and correlation with QUID 勘误:办公室膀胱术在资源受限的设置:诊断的频谱和与QUID的相关性
Pub Date : 2020-01-01 DOI: 10.4103/0189-5117.292287
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引用次数: 0
The prevalence of syphilis in pregnant women in Akwa Ibom State, Southern Nigeria 尼日利亚南部阿夸伊博姆州孕妇梅毒流行情况
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_91_19
M. Al-Mendalawi
First, on employing serology, the authors found that the estimated prevalence of syphilis in a cohort of Nigerian pregnant was 1.98% and the prevalence rates in urban and rural areas were 2.63% and 1.32%, respectively.[1] Owing to the presence of the following limitation, I assume that the study results must be handled with cautions. It is worthy to mention that there are different methods to test for syphilis. Studies have shown that polymerase chain reaction (PCR) technique is superior to serology in precisely detecting syphilis.[2,3] I presume that if the authors employed PCR instead of serology in the study methodology, more precise estimate of syphilis seroprevalence among Nigerian pregnant would be obtained.
首先,在使用血清学时,作者发现尼日利亚孕妇队列中梅毒的估计患病率为1.98%,城市和农村地区的患病率分别为2.63%和1.32%。[1] 由于存在以下限制,我认为必须谨慎处理研究结果。值得一提的是,检测梅毒有不同的方法。研究表明,聚合酶链式反应(PCR)技术在准确检测梅毒方面优于血清学。[2,3]我认为,如果作者在研究方法中使用PCR而不是血清学,将获得尼日利亚孕妇梅毒血清流行率的更精确估计。
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引用次数: 0
Mental health outcome and perceived care needs of women treated for a miscarriage in a low-resource setting 在低资源环境中接受流产治疗的妇女的心理健康结果和感知护理需求
Pub Date : 2020-01-01 DOI: 10.4103/tjog.tjog_44_19
J. Nwafor, V. Obi, C. Obi, C. Ibo, D. Ugoji, B. Onwe, V. Onuchukwu
Introduction: There have been many advances in the management of miscarriage in recent times including the introduction of expectant and medical management protocols. However, a study of the psychological impact of the condition and its management has not received similar attention. Aim: To determine the psychosocial consequences of miscarriages and perceived needs of the patients compared to the care provided by the hospital. Materials and Method: This was a prospective cohort study conducted between January 15, 2018 and April 30, 2019. Participants were recruited on admission and psychological morbidity was assessed at 1 week after a miscarriage in the gynecological clinics. They were screened for psychological morbidities using DASS 21 (Depression, Anxiety and Stress Scale). Results: Of 140 women that participated in the study, severe depression was reported in 8 (5.7%) whereas 12 (8.5%) participants reported symptoms of extremely severe depression. Moderate to severe anxiety was present in 23.5% while extremely severe anxiety was noted among 21.5% of the women. Stress was reported in over half of respondents and severe to extremely severe stress occurred in 19.9% of the participants. Factors significantly associated with psychological morbidities following miscarriage include age ≥35 years, no living child, subfertility, planned pregnancy, and assisted conception. Healthcare providers not listening to the patient's concern, non-participation in decision making, and dissatisfaction with care were associated with adverse psychological outcomes. Conclusion: Psychological morbidity following a miscarriage is common among participants in our study. The provision of the correct information and psychological debriefing may be useful in enabling women to adjust emotionally following miscarriage.
引言:近年来,流产的管理取得了许多进展,包括引入了孕妇和医疗管理方案。然而,对这种情况的心理影响及其管理的研究并没有得到类似的关注。目的:与医院提供的护理相比,确定流产的心理社会后果和患者的感知需求。材料和方法:这是一项在2018年1月15日至2019年4月30日期间进行的前瞻性队列研究。参与者在入院时被招募,并在流产后1周在妇科诊所评估心理发病率。他们使用DASS 21(抑郁、焦虑和压力量表)进行心理疾病筛查。结果:在参与该研究的140名女性中,有8名(5.7%)报告了严重抑郁症,而12名(8.5%)参与者报告了极其严重的抑郁症症状。23.5%的女性存在中度至重度焦虑,21.5%的女性出现极度焦虑。据报道,超过一半的受访者有压力,19.9%的参与者出现了严重到极度严重的压力。与流产后心理疾病显著相关的因素包括年龄≥35岁、没有活孩子、生育能力低下、计划怀孕和辅助受孕。医疗保健提供者不听取患者的担忧、不参与决策以及对护理的不满与不良心理结果有关。结论:流产后的心理发病率在我们研究的参与者中很常见。提供正确的信息和心理汇报可能有助于女性在流产后调整情绪。
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引用次数: 2
期刊
Tropical Journal of Obstetrics and Gynaecology
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