Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol12/1/4
Dhyaa. F. Hassan, H. Yasser, Thi-Qar
: In this research, may insert of all the effects, such as dispersion, nonlinear, gain factor associated with the pumping pulse , attenuation and others in the conclusion the general equation for the propagation of the optical fiber through the laser resonator. In addition, the introduction of the effect of mode locking process using frequency modulation in order to get a stream ultrashort pulses. Selecting an suitable frequency modulated pulses achieved the stream could reach the stage of stability according to a certain number of trips round-trip (RT), since the highest frequency accompanied by a number less than the RT. On the other hand, the increase in R adversely affect the output pulses stream. The interval time between resulted pulses is inversely proportional to frequency modulated. stream pulses can be stable in the energy and pulse width with RT appropriate. increase factor 2 contribute to stability of pulses energy while 3 did not show any effects. The effect of the pumping energy represent of the 0 g worker showed that resulting energy increases with increases this factor. Pulse width 0 T initial and factor 2 T and modulated depth representing of their effects change method the oscillation of the factors resulting pulses.
{"title":"Frequency Mode Locking in Erbium Doped Fiber Laser","authors":"Dhyaa. F. Hassan, H. Yasser, Thi-Qar","doi":"10.32792/utq/utj/vol12/1/4","DOIUrl":"https://doi.org/10.32792/utq/utj/vol12/1/4","url":null,"abstract":": In this research, may insert of all the effects, such as dispersion, nonlinear, gain factor associated with the pumping pulse , attenuation and others in the conclusion the general equation for the propagation of the optical fiber through the laser resonator. In addition, the introduction of the effect of mode locking process using frequency modulation in order to get a stream ultrashort pulses. Selecting an suitable frequency modulated pulses achieved the stream could reach the stage of stability according to a certain number of trips round-trip (RT), since the highest frequency accompanied by a number less than the RT. On the other hand, the increase in R adversely affect the output pulses stream. The interval time between resulted pulses is inversely proportional to frequency modulated. stream pulses can be stable in the energy and pulse width with RT appropriate. increase factor 2 contribute to stability of pulses energy while 3 did not show any effects. The effect of the pumping energy represent of the 0 g worker showed that resulting energy increases with increases this factor. Pulse width 0 T initial and factor 2 T and modulated depth representing of their effects change method the oscillation of the factors resulting pulses.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82870869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/voll12/2/9
Sheren Ali Hussien, K. Al-Fartosi
The present study is designed to investigated the effect of prepared chemical base(R-CH=N-Ar)which consist of (camphr andglycin) on reproductive hormones of female rats.Twenty_fourwistar albino female ratsused in this study, divided intothree groups: the first group was treated orally with olive oil as a control group, the second and third groups treated orally with schiff basedissolved in olive oilat two doses (50 mg/kg and 100 mg/kg) respectively for 21 day.The result showed that Schiff base did not affect level of LH hormone in second and third groups compared with control group while, FSH level increased significantly(p<0.05) in third group only compared with the first and second group. The result indicated a significant increase(p<0.05)in level of progesterone and estrogen hormones in seconedand third groups compared with the controlgroup, also non-signficant different in levels of both hormones between second and third groups.
{"title":"Study, to estimate the effect of new schiff base (R-CH=NAr) on the reproductive hormones of female Rats","authors":"Sheren Ali Hussien, K. Al-Fartosi","doi":"10.32792/utq/utj/voll12/2/9","DOIUrl":"https://doi.org/10.32792/utq/utj/voll12/2/9","url":null,"abstract":"The present study is designed to investigated the effect of prepared chemical base(R-CH=N-Ar)which consist of (camphr andglycin) on reproductive hormones of female rats.Twenty_fourwistar albino female ratsused in this study, divided intothree groups: the first group was treated orally with olive oil as a control group, the second and third groups treated orally with schiff basedissolved in olive oilat two doses (50 mg/kg and 100 mg/kg) respectively for 21 day.The result showed that Schiff base did not affect level of LH hormone in second and third groups compared with control group while, FSH level increased significantly(p<0.05) in third group only compared with the first and second group. The result indicated a significant increase(p<0.05)in level of progesterone and estrogen hormones in seconedand third groups compared with the controlgroup, also non-signficant different in levels of both hormones between second and third groups.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82967135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol12/1/6
Raied Abass, Saleh AL-Hamadany
The role of substitution carbon defect on the structural properties and dielectric constant of monoclinic hafnium dioxide was investigated by adopting density functional theory calculations. Local vibration modes for various doping mechanisms of carbon have also included in the calculations. Results show that carbon substitution for oxygen is more energetically favorable than substitution for hafnium. Additionally, carbon has an anisotropic and divergent impact upon the dielectric constant based upon hosted site. For oxygen site, the dielectric constant achieves 4.709, whereas it decreases to 4.128 for the case of both hafnium sites. Calculated vibrational frequencies (836.09, 862.39 and 1507.64 and 1508.55) provide valuable information toward verifying the existence of carbon in m-HfO 2 .
{"title":"Structural and optical properties of carbon contaminated HfO2: First principle study","authors":"Raied Abass, Saleh AL-Hamadany","doi":"10.32792/utq/utj/vol12/1/6","DOIUrl":"https://doi.org/10.32792/utq/utj/vol12/1/6","url":null,"abstract":"The role of substitution carbon defect on the structural properties and dielectric constant of monoclinic hafnium dioxide was investigated by adopting density functional theory calculations. Local vibration modes for various doping mechanisms of carbon have also included in the calculations. Results show that carbon substitution for oxygen is more energetically favorable than substitution for hafnium. Additionally, carbon has an anisotropic and divergent impact upon the dielectric constant based upon hosted site. For oxygen site, the dielectric constant achieves 4.709, whereas it decreases to 4.128 for the case of both hafnium sites. Calculated vibrational frequencies (836.09, 862.39 and 1507.64 and 1508.55) provide valuable information toward verifying the existence of carbon in m-HfO 2 .","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73837527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol11/3/1
Shatha Q. Al-temimi, Hanaa S. Kadhem, M. Thuwaini
The present study aimed to compare the effect of physical exercise in the morning and evening time on some physiological parameters which comprised from renal function test including blood urea nitrogen (BUN), serum creatinine (S.cr), some of serum electrolyte. (sodium and potassium) and blood pressure. The study included (20) males students volunteers of the second stage - College of Physical Education - University of Basra (10) students from the morning group and (10) students from the evening group. The results Showed that The Bun and S.cr concentration post-exercise in morning and evening group are significant higher than Pre-exercise in the same time, the Bun., S.cr concentration post-exercise in the evening group are higher than post-exercise in morning group (p≥0.05). But no significant (P≥0.05) in Sodium and Potassium . While the SYS and DIS blood Pressure level post-exercise are significant lower than Pre-exercise in the morning and evening group, and found that the SYS and DIS blood Pressure post-exercise in evening group are lower In comparison with post-exercise in morning group (p≥0.05). Conclusion: The physical exercise cause significantly higher in Bun and S.cr, the concentration of Bun and S.cr post-exercise in evening time are higher than post-exercise in morning time, no significant was appeared in sodium and potassium levels. Conversely, significantly lower in SYS and DIS blood Pressure post-exercise.While, SYS and DIS blood Pressure post-exercise in evening time are significant lower In comparison with post-exercise in morning time
{"title":"The effects of physical exercises in the morning and evening time on some physiological parameters","authors":"Shatha Q. Al-temimi, Hanaa S. Kadhem, M. Thuwaini","doi":"10.32792/utq/utj/vol11/3/1","DOIUrl":"https://doi.org/10.32792/utq/utj/vol11/3/1","url":null,"abstract":"The present study aimed to compare the effect of physical exercise in the morning and evening time on some physiological parameters which comprised from renal function test including blood urea nitrogen (BUN), serum creatinine (S.cr), some of serum electrolyte. (sodium and potassium) and blood pressure. The study included (20) males students volunteers of the second stage - College of Physical Education - University of Basra (10) students from the morning group and (10) students from the evening group. The results Showed that The Bun and S.cr concentration post-exercise in morning and evening group are significant higher than Pre-exercise in the same time, the Bun., S.cr concentration post-exercise in the evening group are higher than post-exercise in morning group (p≥0.05). But no significant (P≥0.05) in Sodium and Potassium . While the SYS and DIS blood Pressure level post-exercise are significant lower than Pre-exercise in the morning and evening group, and found that the SYS and DIS blood Pressure post-exercise in evening group are lower In comparison with post-exercise in morning group (p≥0.05). \u0000Conclusion: The physical exercise cause significantly higher in Bun and S.cr, the concentration of Bun and S.cr post-exercise in evening time are higher than post-exercise in morning time, no significant was appeared in sodium and potassium levels. Conversely, significantly lower in SYS and DIS blood Pressure post-exercise.While, SYS and DIS blood Pressure post-exercise in evening time are significant lower In comparison with post-exercise in morning time","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78392884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol12/2/4
Saad Jabbr Nazal
In order to meet the increasing demand of high energy density and long life of energy storage systems, improvement of composite flywheel design approaches have been under development. The goal of this research is to design a flywheel capable of storing 10M-Joules with a mass of 10 Kg, a maximum diameter of 750 mm, and a maximum length of 300 mm, while spinning at a nominal speed of 70,000 RPM. Composite technology is one of the ways to attain extraordinarily high strength-to-weight ratios required for maximum flywheel performance. This report presents a Composite Stodola flywheel design capable of producing 10 M-Joules, with a mass of 10 Kg. The research was conducted to obtain a high quality flywheel for energy storage operations. Elastic, viscoelastic, and fatigue analysis were developed in the design as well as the prediction of the behavior of flywheel.
为了满足储能系统对高能量密度和长寿命日益增长的需求，复合材料飞轮的设计方法不断得到改进。这项研究的目标是设计一个能够存储10 m -焦耳的飞轮，质量为10 Kg，最大直径为750 mm，最大长度为300 mm，同时以70000 RPM的标称速度旋转。复合材料技术是实现飞轮最大性能所需的超高强度重量比的方法之一。本报告介绍了一种复合Stodola飞轮设计，能够产生10 m -焦耳，质量为10 Kg。该研究旨在获得用于储能运行的高质量飞轮。在飞轮的设计和性能预测中进行了弹性、粘弹性和疲劳分析。
{"title":"DESIGN OF A COMPOSITE FLYWHEEL WITH SPECIFIC REQUIRMENTS","authors":"Saad Jabbr Nazal","doi":"10.32792/utq/utj/vol12/2/4","DOIUrl":"https://doi.org/10.32792/utq/utj/vol12/2/4","url":null,"abstract":"In order to meet the increasing demand of high energy density and long life of energy storage systems, improvement of composite flywheel design approaches have been under development. The goal of this research is to design a flywheel capable of storing 10M-Joules with a mass of 10 Kg, a maximum diameter of 750 mm, and a maximum length of 300 mm, while spinning at a nominal speed of 70,000 RPM. \u0000Composite technology is one of the ways to attain extraordinarily high strength-to-weight ratios required for maximum flywheel performance. This report presents a Composite Stodola flywheel design capable of producing 10 M-Joules, with a mass of 10 Kg. \u0000The research was conducted to obtain a high quality flywheel for energy storage operations. Elastic, viscoelastic, and fatigue analysis were developed in the design as well as the prediction of the behavior of flywheel.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"329 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75477336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol11/2/2
L. Algharagholy
Using the density functional theory ‘DFT’ code ‘SIESTA’ combined with a Green’s function scattering approach ‘GFSA’ code ‘GOLLUM’, we investigate the electronic properties of hetero nanotubes, density of states ‘DOS’, electronic band structure BS, transmission coefficient T(E) and current-voltage curve. We simulated four different hetero structures of nanotubes which are: 1- Hetero nanotube with one graphene ring and one boron nitride ring. 2- Hetero nanotube with two graphene ring and one boron nitride rings. 3- Hetero nanotube with three graphene ring and one boron nitride rings. 4- Hetero nanotube with four graphene ring and one boron nitride rings nanotubes. The results show that there is a clear reduction in energy gap ‘Eg’ of hetero nanotubes comparing with the insulator boron nitride (Eg 4.6 eV) and also this kind of hetero nanotubes have zero states at Fermi energy comparing with conductor carbon nanotube which has finite states at Fermi energy. This is could be a good method to design a semiconductor with desirable band gap.
{"title":"Theoretical Study Toward Understanding the Electronic Properties of Armchair Hetero Nanotubes","authors":"L. Algharagholy","doi":"10.32792/utq/utj/vol11/2/2","DOIUrl":"https://doi.org/10.32792/utq/utj/vol11/2/2","url":null,"abstract":"Using the density functional theory ‘DFT’ code ‘SIESTA’ combined with a Green’s function scattering approach ‘GFSA’ code ‘GOLLUM’, we investigate the electronic properties of hetero nanotubes, density of states ‘DOS’, electronic band structure BS, transmission coefficient T(E) and current-voltage curve. We simulated four different hetero structures of nanotubes which are: 1- Hetero nanotube with one graphene ring and one boron nitride ring. 2- Hetero nanotube with two graphene ring and one boron nitride rings. 3- Hetero nanotube with three graphene ring and one boron nitride rings. 4- Hetero nanotube with four graphene ring and one boron nitride rings nanotubes. The results show that there is a clear reduction in energy gap ‘Eg’ of hetero nanotubes comparing with the insulator boron nitride (Eg 4.6 eV) and also this kind of hetero nanotubes have zero states at Fermi energy comparing with conductor carbon nanotube which has finite states at Fermi energy. This is could be a good method to design a semiconductor with desirable band gap.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76297747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol12/1/7
H. Hammood
The radon exhalation rate in term of area was variable (10.4-52.1 mBq.m -2 .h -1 ) with the average value (30.1 mBq.m -2 .h -1 ) while the radon exhalation rate in term of mass was variable (1.09-5.45 mBq.kg -1 .h -1 ) with the average value (3.15 mBq.kg -1 .h -1 ) and radium concentration is varied (0.144-0.722 Bq.kg -1 ) with the average value (0.417 Bq.kg -1 ). The annual effective dose of radium for three population groups was carried out, and lifetime risk assessment was about 10 -4 when used this water as a drinking water. The results compared with safe recommended limit to radium concentration and the annual effective dose of radium in drinking water according to WHO and with other countries.
{"title":"Radon Exhalation Rate and Mean Annual Effective Dose from Radium concentration from Gharraf Canal and Its Some Branches in Thi Qar Governorate (Iraq)","authors":"H. Hammood","doi":"10.32792/utq/utj/vol12/1/7","DOIUrl":"https://doi.org/10.32792/utq/utj/vol12/1/7","url":null,"abstract":"The radon exhalation rate in term of area was variable (10.4-52.1 mBq.m -2 .h -1 ) with the average value (30.1 mBq.m -2 .h -1 ) while the radon exhalation rate in term of mass was variable (1.09-5.45 mBq.kg -1 .h -1 ) with the average value (3.15 mBq.kg -1 .h -1 ) and radium concentration is varied (0.144-0.722 Bq.kg -1 ) with the average value (0.417 Bq.kg -1 ). The annual effective dose of radium for three population groups was carried out, and lifetime risk assessment was about 10 -4 when used this water as a drinking water. The results compared with safe recommended limit to radium concentration and the annual effective dose of radium in drinking water according to WHO and with other countries.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78938854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol12/2/3
Sally Bassm Kazem, Abdulwasi Salih
The effect of output coupler mirrors reflectivity on characteristics of Stokes Raman pulse, which is generated from passive Q-switching intracavity Raman media laser system has been studied. A software computer program based on this study to solve the rate equations of instantaneous performance of the mentioned system (Nd:YVO4, Cr+4:YAG and BaWO4 ) numerically by Runge- kutta-Fehalberg method. The study shows that the energy, duration, and the power of the pulse increasing when the output coupler mirrors reflectivity increasing.
{"title":"Study the effect of output coupler mirror reflectivity on Stokes Raman laser pulse characteristics","authors":"Sally Bassm Kazem, Abdulwasi Salih","doi":"10.32792/utq/utj/vol12/2/3","DOIUrl":"https://doi.org/10.32792/utq/utj/vol12/2/3","url":null,"abstract":"The effect of output coupler mirrors reflectivity on characteristics of Stokes Raman pulse, which is generated from passive Q-switching intracavity Raman media laser system has been studied. A software computer program based on this study to solve the rate equations of instantaneous performance of the mentioned system (Nd:YVO4, Cr+4:YAG and BaWO4 ) numerically by Runge- kutta-Fehalberg method. The study shows that the energy, duration, and the power of the pulse increasing when the output coupler mirrors reflectivity increasing.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90376304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol11/4/9
M. Thuwaini, Hanaa S. Kadhem, H. Hatem
The goal of current study was to actualization the protective effect of the probability of Fluvastatin hepatoprotection. Paracetamol (PCM) overdose can cause hepatotoxicity with oxidative stress as one of the possible mechanisms mediating the event. In present study, the effects of Fluvastatin(10mg/kg) and (20mg/kg) on PCM-induced hepatotoxicity were examined. Rats were divided randomly into five groups containing 9 rats each. The control group received normal saline (the vehicle). Other groups were treated with Fluvastain alone (20mg/kg), PCM alone (600mg/kg), (600mg/kg PCM + 10mg/kg Fluvastatin), and (20mg/kg PCM + 20mg/kg Fluvastatin) respectively, for 4 weeks. Paracetamol induced male rat hepatotoxicity represented by significant decline in the serum total albumin (P< 0.05). However, the study appeared significantly increment (P< 0.0001), bilirubin, ALT, AST and ALP as shown in group2 (induction group) in comparison with group1 (control group). However, simultaneous administration of fluvastatin (10mg/kg and 20mg/kg) with paracetamol, significantely was attenuated the adverse changes in the serum total albumin, bilirubin, ALT IU/L, AST, and ALP. On the other hand, the biochemical observations were supported by histopathological examination of liver sections. Where, showed marked attenuated the severity of paracetamol –induced hepatotoxicity, However, all these toxic effects were improved by administration of fluvastatin, but didn’t bring them to the control limits.
{"title":"Reducing the effects of paracetamol-induced hepatic damage in rat With fluvastatin drug","authors":"M. Thuwaini, Hanaa S. Kadhem, H. Hatem","doi":"10.32792/utq/utj/vol11/4/9","DOIUrl":"https://doi.org/10.32792/utq/utj/vol11/4/9","url":null,"abstract":"The goal of current study was to actualization the protective effect of the probability of Fluvastatin hepatoprotection. Paracetamol (PCM) overdose can cause hepatotoxicity with oxidative stress as one of the possible mechanisms mediating the event. In present study, the effects of Fluvastatin(10mg/kg) and (20mg/kg) on PCM-induced hepatotoxicity were examined. Rats were divided randomly into five groups containing 9 rats each. The control group received normal saline (the vehicle). Other groups were treated with Fluvastain alone (20mg/kg), PCM alone (600mg/kg), (600mg/kg PCM + 10mg/kg Fluvastatin), and (20mg/kg PCM + 20mg/kg Fluvastatin) respectively, for 4 weeks. Paracetamol induced male rat hepatotoxicity represented by significant decline in the serum total albumin (P< 0.05). However, the study appeared significantly increment (P< 0.0001), bilirubin, ALT, AST and ALP as shown in group2 (induction group) in comparison with group1 (control group). However, simultaneous administration of fluvastatin (10mg/kg and 20mg/kg) with paracetamol, significantely was attenuated the adverse changes in the serum total albumin, bilirubin, ALT IU/L, AST, and ALP. \u0000On the other hand, the biochemical observations were supported by histopathological examination of liver sections. Where, showed marked attenuated the severity of paracetamol –induced hepatotoxicity, However, all these toxic effects were improved by administration of fluvastatin, but didn’t bring them to the control limits.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89651130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-22DOI: 10.32792/utq/utj/vol12/1/1
S. Najim
Dopamine (DA) is one of the most important catecholamine neurotransmitters in the human central nervous system in the brain and plays a key role in the functioning of the renal, hormonal, and cardiovascular systems. Abnormal release of DA will contribute to some diseases such as Alzheimer’s and Parkinson's disease. Therefore, the sensitive determination of DA becomes increasingly significant in the field of clinical disease diagnosis and the research of physiological functions. Progesterone is an essential for the development and cyclical regulation of hormone responsive tissues including the breast and reproductive tract. In the breast, progesterone acts in concert with estrogen to promote proliferative and pro-survival gene programs. Progesterone has actions in breast cancer. This paper shows a spectrophotometric method for determination dopamine and progesterone concentration in serum samples, fifty six veins blood samples collected from healthy control and breast cancer patient groups. The analytical data obtained by using UV-Spectrophotometer ( max = 250, 266 nm), linearity (0.5 - 2.0, 0.25 - 1.5 ng/ml) for dopamine, progesterone respectively. The molar absorptivity ( ), correlation coefficient (R 2 ) and limit of detection (LOD) for dopamine, progesterone ( =2.5156 10 6 , 4.1935 10 6 L.mol -1 cm -1 ), (R 2 = 0.9979, 0.99957) and (0.64, 0.57 ng/ml) respectively. The results show significant differences between the concentrations of dopamine and progesterone in control and breast cancer patient groups (p 0.05).It is fast, sensitive, selective and reliable quantification spectrophotometric method used in complex biological samples.
{"title":"Spectrophotometric determination of progesterone and dopamine in breast cancer serum","authors":"S. Najim","doi":"10.32792/utq/utj/vol12/1/1","DOIUrl":"https://doi.org/10.32792/utq/utj/vol12/1/1","url":null,"abstract":"Dopamine (DA) is one of the most important catecholamine neurotransmitters in the human central nervous system in the brain and plays a key role in the functioning of the renal, hormonal, and cardiovascular systems. Abnormal release of DA will contribute to some diseases such as Alzheimer’s and Parkinson's disease. Therefore, the sensitive determination of DA becomes increasingly significant in the field of clinical disease diagnosis and the research of physiological functions. Progesterone is an essential for the development and cyclical regulation of hormone responsive tissues including the breast and reproductive tract. In the breast, progesterone acts in concert with estrogen to promote proliferative and pro-survival gene programs. Progesterone has actions in breast cancer. This paper shows a spectrophotometric method for determination dopamine and progesterone concentration in serum samples, fifty six veins blood samples collected from healthy control and breast cancer patient groups. The analytical data obtained by using UV-Spectrophotometer ( max = 250, 266 nm), linearity (0.5 - 2.0, 0.25 - 1.5 ng/ml) for dopamine, progesterone respectively. The molar absorptivity ( ), correlation coefficient (R 2 ) and limit of detection (LOD) for dopamine, progesterone ( =2.5156 10 6 , 4.1935 10 6 L.mol -1 cm -1 ), (R 2 = 0.9979, 0.99957) and (0.64, 0.57 ng/ml) respectively. The results show significant differences between the concentrations of dopamine and progesterone in control and breast cancer patient groups (p 0.05).It is fast, sensitive, selective and reliable quantification spectrophotometric method used in complex biological samples.","PeriodicalId":23465,"journal":{"name":"University of Thi-Qar Journal","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80516694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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