首页 > 最新文献

Vascular最新文献

英文 中文
Epidemiology of the use of inferior vena cava filters in Brazil between 2008 and 2019. 2008 年至 2019 年巴西使用下腔静脉滤器的流行病学情况。
IF 1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-10-01 Epub Date: 2023-03-21 DOI: 10.1177/17085381231164923
Andressa Cristina Sposato Louzada, Dafne Braga Diamante Leiderman, Marcelo Fiorelli Alexandrino da Silva, Maria Fernanda Cassino Portugal, João Carlos de Campos Guerra, Marcelo Passos Teivelis, Nelson Wolosker

Objectives: The primary objective was to study the totality of inferior vena cava filter placements and their temporal and geographic distribution in the Brazilian Public Health System, which insures more than 160 million Brazilians. The secondary objective was to analyze in-hospital mortality after filter placement and deaths due to pulmonary embolism.

Methods: Public and open data on in-hospital mortality due to pulmonary embolism and on rates of inferior vena cava filters placement, its associated diagnosis, and in-hospital mortality in Brazilian public hospitals between January 2008 and December 2019 were extracted from Ministry of Health databases.

Results: A total of 9108 inferior vena cava filters were placed, 98.18% of which was therapeutic. We observed a significant increase in the use of these devices over the years, from 508 inferior vena cava filters placed in 2008 to 965 in 2019. In-hospital mortality rate in patients who received inferior vena cava filters was 6.21%, stable over time, and 96.64% of causes of these causes were attributed to venous thromboembolism. The in-hospital mortality rate due to pulmonary embolism, regardless of the placement of vena cava filters, has increased significantly.

Conclusion: We observed a low but increasing rate of inferior vena cava filter placements in Brazil between 2008 and 2019, most indications were therapeutic. Our findings were heterogeneous across Brazilian regions and contrasted to those observed in the USA, which is likely due to cultural and socioeconomic factors.

研究目的主要目的是研究巴西公共卫生系统中下腔静脉滤器置入的总体情况及其时间和地理分布,该系统为超过1.6亿巴西人提供保险。次要目标是分析放置过滤器后的院内死亡率和肺栓塞导致的死亡:从卫生部数据库中提取了2008年1月至2019年12月期间巴西公立医院因肺栓塞导致的院内死亡率、下腔静脉滤器置入率、相关诊断和院内死亡率的公开数据:共放置了9108个下腔静脉滤器,其中98.18%是治疗性的。我们观察到这些设备的使用量逐年大幅增加,从 2008 年的 508 个下腔静脉滤器增加到 2019 年的 965 个。接受下腔静脉滤器治疗的患者的院内死亡率为6.21%,随着时间的推移保持稳定,其中96.64%的原因归咎于静脉血栓栓塞。无论是否放置腔静脉滤器,肺栓塞导致的院内死亡率都显著上升:我们观察到,2008 年至 2019 年期间,巴西下腔静脉滤器置入率较低,但在不断上升,大多数适应症是治疗性的。我们的研究结果在巴西各地区不尽相同,与在美国观察到的结果形成鲜明对比,这可能是文化和社会经济因素造成的。
{"title":"Epidemiology of the use of inferior vena cava filters in Brazil between 2008 and 2019.","authors":"Andressa Cristina Sposato Louzada, Dafne Braga Diamante Leiderman, Marcelo Fiorelli Alexandrino da Silva, Maria Fernanda Cassino Portugal, João Carlos de Campos Guerra, Marcelo Passos Teivelis, Nelson Wolosker","doi":"10.1177/17085381231164923","DOIUrl":"10.1177/17085381231164923","url":null,"abstract":"<p><strong>Objectives: </strong>The primary objective was to study the totality of inferior vena cava filter placements and their temporal and geographic distribution in the Brazilian Public Health System, which insures more than 160 million Brazilians. The secondary objective was to analyze in-hospital mortality after filter placement and deaths due to pulmonary embolism.</p><p><strong>Methods: </strong>Public and open data on in-hospital mortality due to pulmonary embolism and on rates of inferior vena cava filters placement, its associated diagnosis, and in-hospital mortality in Brazilian public hospitals between January 2008 and December 2019 were extracted from Ministry of Health databases.</p><p><strong>Results: </strong>A total of 9108 inferior vena cava filters were placed, 98.18% of which was therapeutic. We observed a significant increase in the use of these devices over the years, from 508 inferior vena cava filters placed in 2008 to 965 in 2019. In-hospital mortality rate in patients who received inferior vena cava filters was 6.21%, stable over time, and 96.64% of causes of these causes were attributed to venous thromboembolism. The in-hospital mortality rate due to pulmonary embolism, regardless of the placement of vena cava filters, has increased significantly.</p><p><strong>Conclusion: </strong>We observed a low but increasing rate of inferior vena cava filter placements in Brazil between 2008 and 2019, most indications were therapeutic. Our findings were heterogeneous across Brazilian regions and contrasted to those observed in the USA, which is likely due to cultural and socioeconomic factors.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1092-1098"},"PeriodicalIF":1.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9500465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malnutrition is associated with adverse 30-day outcomes after endovascular repair of abdominal aortic aneurysm. 营养不良与腹主动脉瘤血管内修复术后 30 天的不良预后有关。
IF 1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-27 DOI: 10.1177/17085381241289484
Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen

Background: Malnutrition is particularly pertinent in patients undergoing vascular surgery, who frequently present with a high burden of comorbidities and advanced age that can impede nutrient absorption. While previous studies have established that vascular surgery patients with malnutrition had poorer outcomes, the impact of nutritional status in patients undergoing endovascular aneurysm repair (EVAR) has not yet been investigated. Therefore, this study aimed to assess the effect of malnutrition on 30-day outcomes following non-ruptured EVAR.

Methods: Patients who had infrarenal EVAR were identified in the ACS-NSQIP targeted database from 2012-2022. Exclusion criteria included age less than 18 years, ruptured aneurysm, and emergency. Malnutrition was defined as patients with preoperative weight loss of greater than 10% decrease in body weight in the 6 months immediately preceding the surgery. A 1:5 propensity-score matching was used to match demographics, baseline characteristics, aneurysm diameter, distant aneurysm extent, anesthesia, and concomitant procedures between patients with and without malnutrition. Thirty-day postoperative outcomes were examined.

Results: There were 154 (0.94%) patients with malnutrition who went under non-ruptured EVAR. Meanwhile, 16,309 patients without malnutrition went under intact EVAR, where 737 of them were matched to all malnutrition patients. Malnourished patients had more comorbidity burdens. After propensity-score matching, patients with malnutrition had elevated but non-significant 30-day mortality (5.92% vs 2.99%, p = .09). However, malnutrition patients had higher risks of renal complications (2.63% vs 0.68%, p = .04), bleeding requiring transfusion (22.37% vs 14.38%, p = .02), and unplanned reoperation (11.18% vs 4.88%, p = .01), as well as longer length of stay (6.11 ± 7.91 vs 4.44 ± 6.22 days, p < .02).

Conclusion: Patients with malnutrition experienced higher rates of morbidity after non-ruptured EVAR. Targeting malnutrition could be a strategy for preventing complications after EVAR and proper preoperative malnutritional management could be warranted.

背景:接受血管外科手术的患者营养不良问题尤为突出,因为这些患者通常合并有多种疾病,而且年龄较大,营养吸收可能会受到影响。以往的研究表明,营养不良的血管手术患者预后较差,但营养状况对血管内动脉瘤修补术(EVAR)患者的影响尚未得到研究。因此,本研究旨在评估营养不良对非破裂EVAR术后30天预后的影响:方法:2012-2022年期间,在ACS-NSQIP目标数据库中确定了接受肾下EVAR的患者。排除标准包括年龄小于 18 岁、动脉瘤破裂和急诊。营养不良是指患者术前体重下降超过 10%,且在手术前 6 个月内体重下降超过 10%。采用1:5倾向得分匹配法对有营养不良和无营养不良的患者进行人口统计学、基线特征、动脉瘤直径、远处动脉瘤范围、麻醉和同时进行的手术进行匹配。结果:结果:共有154名(0.94%)营养不良患者接受了非破裂EVAR手术。同时,16309 名无营养不良的患者接受了完整的 EVAR,其中 737 人与所有营养不良患者匹配。营养不良患者的合并症负担更重。经过倾向分数匹配后,营养不良患者的30天死亡率升高,但并不显著(5.92% vs 2.99%,P = 0.09)。然而,营养不良患者发生肾脏并发症(2.63% vs 0.68%,p = .04)、出血需要输血(22.37% vs 14.38%,p = .02)和意外再次手术(11.18% vs 4.88%,p = .01)的风险更高,住院时间也更长(6.11 ± 7.91 vs 4.44 ± 6.22 天,p < .02):结论:营养不良患者在非破裂EVAR术后发病率较高。针对营养不良可能是预防EVAR术后并发症的一种策略,因此术前应进行适当的营养管理。
{"title":"Malnutrition is associated with adverse 30-day outcomes after endovascular repair of abdominal aortic aneurysm.","authors":"Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen","doi":"10.1177/17085381241289484","DOIUrl":"https://doi.org/10.1177/17085381241289484","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is particularly pertinent in patients undergoing vascular surgery, who frequently present with a high burden of comorbidities and advanced age that can impede nutrient absorption. While previous studies have established that vascular surgery patients with malnutrition had poorer outcomes, the impact of nutritional status in patients undergoing endovascular aneurysm repair (EVAR) has not yet been investigated. Therefore, this study aimed to assess the effect of malnutrition on 30-day outcomes following non-ruptured EVAR.</p><p><strong>Methods: </strong>Patients who had infrarenal EVAR were identified in the ACS-NSQIP targeted database from 2012-2022. Exclusion criteria included age less than 18 years, ruptured aneurysm, and emergency. Malnutrition was defined as patients with preoperative weight loss of greater than 10% decrease in body weight in the 6 months immediately preceding the surgery. A 1:5 propensity-score matching was used to match demographics, baseline characteristics, aneurysm diameter, distant aneurysm extent, anesthesia, and concomitant procedures between patients with and without malnutrition. Thirty-day postoperative outcomes were examined.</p><p><strong>Results: </strong>There were 154 (0.94%) patients with malnutrition who went under non-ruptured EVAR. Meanwhile, 16,309 patients without malnutrition went under intact EVAR, where 737 of them were matched to all malnutrition patients. Malnourished patients had more comorbidity burdens. After propensity-score matching, patients with malnutrition had elevated but non-significant 30-day mortality (5.92% vs 2.99%, <i>p</i> = .09). However, malnutrition patients had higher risks of renal complications (2.63% vs 0.68%, <i>p</i> = .04), bleeding requiring transfusion (22.37% vs 14.38%, <i>p</i> = .02), and unplanned reoperation (11.18% vs 4.88%, <i>p</i> = .01), as well as longer length of stay (6.11 ± 7.91 vs 4.44 ± 6.22 days, <i>p</i> < .02).</p><p><strong>Conclusion: </strong>Patients with malnutrition experienced higher rates of morbidity after non-ruptured EVAR. Targeting malnutrition could be a strategy for preventing complications after EVAR and proper preoperative malnutritional management could be warranted.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381241289484"},"PeriodicalIF":1.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revascularization of superior mesenteric artery occlusion via the arc of Buhler: A case report and literature review. 通过布勒弧对肠系膜上动脉闭塞进行血管重建:病例报告和文献综述。
IF 1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-27 DOI: 10.1177/17085381241289485
Wei Huang, Ke Wang, Yang Liu, Qi-Qi Wang, Hai-Jun Wei, Chun-Shui He

Background: To report revascularization of a superior mesenteric artery (SMA) ostial occlusion via the Arc of Buhler.

Case report: A 62-year-old female presented with 2 months of recurrent abdominal distension and postprandial pain. Computed tomography angiography (CTA) revealed ostial occlusion of the SMA with distal perfusion via the Arc of Buhler (connecting the celiac trunk and SMA). Conventional endovascular techniques failed. A 0.014 guidewire was passed retrograde through the occlusion via the Arc of Buhler. The guidewire was captured from the femoral sheath and balloon angioplasty with stent placement was performed. The patient had complete symptom resolution post-procedure.

Conclusions: Retrograde revascularization via the Arc of Buhler is an effective method for treating the initial segment occlusion of the SMA.

背景:报告通过布勒弧(Arc of Buhler)对肠系膜上动脉(SMA)闭塞进行再血管化的病例报告:一名 62 岁的女性因反复腹胀和餐后疼痛就诊 2 个月。计算机断层扫描血管造影(CTA)显示,SMA 闭塞,远端通过布勒弧(连接腹腔干和 SMA)灌注。传统的血管内技术未能奏效。一根 0.014 英寸的导丝通过布勒弧逆行穿过闭塞处。从股骨鞘中取出导丝,进行了带支架的球囊血管成形术。患者术后症状完全缓解:结论:通过布勒弧逆行血管再通手术是治疗 SMA 初段闭塞的有效方法。
{"title":"Revascularization of superior mesenteric artery occlusion via the arc of Buhler: A case report and literature review.","authors":"Wei Huang, Ke Wang, Yang Liu, Qi-Qi Wang, Hai-Jun Wei, Chun-Shui He","doi":"10.1177/17085381241289485","DOIUrl":"https://doi.org/10.1177/17085381241289485","url":null,"abstract":"<p><strong>Background: </strong>To report revascularization of a superior mesenteric artery (SMA) ostial occlusion via the Arc of Buhler.</p><p><strong>Case report: </strong>A 62-year-old female presented with 2 months of recurrent abdominal distension and postprandial pain. Computed tomography angiography (CTA) revealed ostial occlusion of the SMA with distal perfusion via the Arc of Buhler (connecting the celiac trunk and SMA). Conventional endovascular techniques failed. A 0.014 guidewire was passed retrograde through the occlusion via the Arc of Buhler. The guidewire was captured from the femoral sheath and balloon angioplasty with stent placement was performed. The patient had complete symptom resolution post-procedure.</p><p><strong>Conclusions: </strong>Retrograde revascularization via the Arc of Buhler is an effective method for treating the initial segment occlusion of the SMA.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381241289485"},"PeriodicalIF":1.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endovascular solutions for symptomatic free-floating thrombus in thoracic aorta in rheumatoid arthritis patients: Two clinical cases. 类风湿性关节炎患者胸主动脉无症状游离血栓的血管内解决方案:两个临床病例。
IF 1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-20 DOI: 10.1177/17085381241269747
G Mastrangelo, P Di Sebastiano, V Palazzo

Objectives: We present two clinical cases of association between symptomatic free-floating thrombus (FFT) in thoracic aorta and rheumatoid arthritis (RA).

Methods: In the first patient, we observed a recent onset of peripheral and visceral signs of embolization: after a first treatment with anticoagulation, our Aortic team scheduled the coverage of FFT (sited in zone 1 of the aortic arch) with an anatomical debranching of anonymous trunk and left carotid artery, a left carotid-subclavian bypass, and a TEVAR of the aortic arch with proximal landing in zone 0 of the arch. The second case was characterized by chest pain, left upper limb ischemia, and CTA evidence of an FFT in zone 3 of the aortic arch; we planned a chimney-TEVAR on the left subclavian artery and descending thoracic aorta (with proximal landing in zone 2 of the aortic arch) to exclude the FFT.

Results: No complications resulted and no new embolic episodes were registered.

Conclusions: Evaluating the aorta is warranted in all patients with peripheral emboli of uncertain pathogenesis. In our opinion, the endovascular treatment of a symptomatic FFT could represent an effective and safe solution in a patient fit for endovascular surgery, but larger studies are required to define a personalized treatment strategy.

目的:介绍两例胸主动脉症状性游离血栓(FFT)与类风湿关节炎(RA)相关的临床病例:我们介绍了两例胸主动脉无症状游离血栓(FFT)与类风湿性关节炎(RA)相关的临床病例:在第一例患者中,我们观察到近期出现的外周和内脏栓塞征象:在首次抗凝治疗后,我们的主动脉团队安排对 FFT(位于主动脉弓 1 区)进行覆盖,同时对无名动脉干和左颈动脉进行解剖学去分支,进行左颈动脉-锁骨下旁路手术,并在主动脉弓 0 区进行近端着床的 TEVAR。第二个病例的特点是胸痛、左上肢缺血,CTA显示主动脉弓3区有FFT;我们计划对左锁骨下动脉和胸主动脉降支(近端着陆于主动脉弓2区)进行烟囱式TEVAR,以排除FFT:无并发症,无新的栓塞发生:结论:对于所有发病机制不明的外周栓塞患者,都有必要对主动脉进行评估。我们认为,对于适合进行血管内手术的患者,对无症状的 FFT 进行血管内治疗是一种有效而安全的解决方案,但需要进行更大规模的研究,以确定个性化的治疗策略。
{"title":"Endovascular solutions for symptomatic free-floating thrombus in thoracic aorta in rheumatoid arthritis patients: Two clinical cases.","authors":"G Mastrangelo, P Di Sebastiano, V Palazzo","doi":"10.1177/17085381241269747","DOIUrl":"https://doi.org/10.1177/17085381241269747","url":null,"abstract":"<p><strong>Objectives: </strong>We present two clinical cases of association between symptomatic free-floating thrombus (FFT) in thoracic aorta and rheumatoid arthritis (RA).</p><p><strong>Methods: </strong>In the first patient, we observed a recent onset of peripheral and visceral signs of embolization: after a first treatment with anticoagulation, our Aortic team scheduled the coverage of FFT (sited in zone 1 of the aortic arch) with an anatomical debranching of anonymous trunk and left carotid artery, a left carotid-subclavian bypass, and a TEVAR of the aortic arch with proximal landing in zone 0 of the arch. The second case was characterized by chest pain, left upper limb ischemia, and CTA evidence of an FFT in zone 3 of the aortic arch; we planned a chimney-TEVAR on the left subclavian artery and descending thoracic aorta (with proximal landing in zone 2 of the aortic arch) to exclude the FFT.</p><p><strong>Results: </strong>No complications resulted and no new embolic episodes were registered.</p><p><strong>Conclusions: </strong>Evaluating the aorta is warranted in all patients with peripheral emboli of uncertain pathogenesis. In our opinion, the endovascular treatment of a symptomatic FFT could represent an effective and safe solution in a patient fit for endovascular surgery, but larger studies are required to define a personalized treatment strategy.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381241269747"},"PeriodicalIF":1.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical variations of origin of the internal carotid artery: Report of two cases and systematic review of the literature 颈内动脉起源的解剖变异:两例病例报告和文献系统回顾
IF 1.1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-19 DOI: 10.1177/17085381241283095
Lucia Ramputi, Daniela Mazzaccaro, Karima Tissir, Manuel Bruno Trevisan, Gianluca Conte, Giovanni Nano, Lorenzo Menicanti, Serenella Castelvecchio
BackgroundAnatomical variations of origin of the internal carotid artery (ICA) are very uncommon and may pose a diagnostic and therapeutic challenge.ObjectiveWe report a case of direct origin of the right ICA from the innominate artery (aplasia of common carotid artery) and a case of duplication of right ICA in healthy patients who performed duplex ultrasound (DUS) for primary cardiovascular prevention screening.MethodsIn both cases, the ultrasound scan was performed both in a transverse plane and on the longitudinal axis, and in one of the two cases, a computed tomography angiography was performed to confirm the diagnosis. A review of the current literature about anatomical variations of origin of carotid arteries was also performed.ResultsThe most frequent congenital anomaly is represented by the aplasia of the CCA, followed by the agenesis and by the duplication of the ICA. In most cases, the anomaly is discovered occasionally and symptoms are aspecific. Diagnosis is usually confirmed through a multimodality imaging approach, including DUS of extracranial carotid arteries, magnetic resonance imaging (MRI), and computed tomographic angiography. In most cases, treatment was conservative, with pharmacological therapy aimed at the symptoms.ConclusionThe recognition of such variations is mandatory, particularly when the patient needs a surgical treatment that may involve the vessel with the anatomical variations.
背景颈内动脉(ICA)起源的解剖变异非常罕见,可能会给诊断和治疗带来挑战。目的我们报告了一例右侧ICA直接起源于髂内动脉(颈总动脉增生)的病例和一例右侧ICA重复的病例,这两例病例均为健康患者,他们在进行心血管初级预防筛查时接受了双工超声(DUS)检查。方法在这两个病例中,超声扫描均在横向平面和纵向轴上进行,其中一个病例还进行了计算机断层扫描血管造影以确诊。结果最常见的先天性畸形是 CCA 增生,其次是缺失和 ICA 重复。在大多数病例中,畸形是偶尔发现的,症状也不明显。诊断通常需要通过多模态成像方法来确认,包括颅外颈动脉的 DUS、磁共振成像(MRI)和计算机断层扫描血管造影。在大多数病例中,治疗都是保守的,针对症状进行药物治疗。
{"title":"Anatomical variations of origin of the internal carotid artery: Report of two cases and systematic review of the literature","authors":"Lucia Ramputi, Daniela Mazzaccaro, Karima Tissir, Manuel Bruno Trevisan, Gianluca Conte, Giovanni Nano, Lorenzo Menicanti, Serenella Castelvecchio","doi":"10.1177/17085381241283095","DOIUrl":"https://doi.org/10.1177/17085381241283095","url":null,"abstract":"BackgroundAnatomical variations of origin of the internal carotid artery (ICA) are very uncommon and may pose a diagnostic and therapeutic challenge.ObjectiveWe report a case of direct origin of the right ICA from the innominate artery (aplasia of common carotid artery) and a case of duplication of right ICA in healthy patients who performed duplex ultrasound (DUS) for primary cardiovascular prevention screening.MethodsIn both cases, the ultrasound scan was performed both in a transverse plane and on the longitudinal axis, and in one of the two cases, a computed tomography angiography was performed to confirm the diagnosis. A review of the current literature about anatomical variations of origin of carotid arteries was also performed.ResultsThe most frequent congenital anomaly is represented by the aplasia of the CCA, followed by the agenesis and by the duplication of the ICA. In most cases, the anomaly is discovered occasionally and symptoms are aspecific. Diagnosis is usually confirmed through a multimodality imaging approach, including DUS of extracranial carotid arteries, magnetic resonance imaging (MRI), and computed tomographic angiography. In most cases, treatment was conservative, with pharmacological therapy aimed at the symptoms.ConclusionThe recognition of such variations is mandatory, particularly when the patient needs a surgical treatment that may involve the vessel with the anatomical variations.","PeriodicalId":23549,"journal":{"name":"Vascular","volume":"2 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142260626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can wound blush be used as an indicator for termination of endovascular procedures in chronic limb-threatening ischemia patients? 伤口淤血能否作为慢性肢体缺血患者终止血管内手术的指标?
IF 1.1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-10 DOI: 10.1177/17085381241283096
Mohammed Shahat, Ashraf G Taha, Ashraf Elnaggar, Hesham Aboloyoun
IntroductionPredicting the outcomes of endovascular revascularization of chronic limb-threatening ischemia (CLTI) patients with foot wounds can be challenging. Angiographic wound blush (WB) assessment has been found to be a helpful tool to assess wound perfusion. The aim of this study is to evaluate WB during endovascular revascularization of CLTI patients and its effects on treatment outcomes.MethodsThis prospective study included all CLTI patients with foot wounds who underwent successful endovascular revascularization of infrainguinal arterial disease between 2019 and 2021. Patients were grouped according to the WB status into positive WB (group A) and negative WB (group B). Both groups were compared for demographics, comorbidities, clinical picture, and 12-month limb-based patency (LBP) and amputation-free survival (AFS) rates.ResultsThe study included 69 patients of Rutherford classes 5 (46.4%) and 6 (53.6%), with the main arterial lesion located at the femoropopliteal (58%) or infrapopliteal (42%) segments. Completion angiography showed positive WB in 38 (55.1%) patients and negative WB in 31 (44.9%) patients. Both groups were comparable regarding patient presentation, site of the main arterial lesion, and distribution of foot lesions in relation to the feeding artery. The overall 12-month LBP and AFS rates were 21.7% and 39.1%, respectively, with significantly better rates in group A than in group B (LBP, 31.6% vs 9.7%, p = 0.001 and AFS, 54.1% vs 22.2%, p = 0.006, respectively). Successful angiosome-based direct flow to the foot was achieved in 38 patients (55.1%), resulting in significantly better 12-month AFS rates than those with indirect revascularization (54.8% vs 26.3%, p = 0.036, respectively), despite the comparable 12-LBP rates between the direct and indirect revascularization groups (29% vs 15.8%, p = 0.133, respectively). Multivariate logistic regression analysis identified smoking as a significant predictor of a major amputation, whereas positive WB and successful direct revascularization were significant predictors of limb salvage.ConclusionsWB can serve as a predictor for AFS and LBP during endovascular revascularization of CLTI patients with foot wounds. A positive WB may guide the decision to conclude an endovascular procedure, potentially avoiding unnecessary complicated maneuvers to recanalize more vessels. Conversely, a negative WB may suggest the need for further revascularization attempts to augment wound perfusion and healing.
导言预测患有足部伤口的慢性肢体缺血(CLTI)患者血管内再通术的疗效具有挑战性。血管造影伤口红晕(WB)评估被认为是评估伤口灌注的有效工具。本研究旨在评估CLTI患者血管内再通术期间的WB及其对治疗结果的影响。方法这项前瞻性研究纳入了2019年至2021年期间成功接受腹股沟下动脉疾病血管内再通术的所有足部伤口CLTI患者。根据 WB 状态将患者分为阳性 WB(A 组)和阴性 WB(B 组)。两组患者的人口统计学、合并症、临床表现以及12个月的肢体通畅率(LBP)和无截肢生存率(AFS)进行了比较。结果研究纳入了69名卢瑟福分级为5级(46.4%)和6级(53.6%)的患者,主要动脉病变位于股骨干(58%)或股骨干下段(42%)。完成血管造影显示,38 例(55.1%)患者的 WB 阳性,31 例(44.9%)患者的 WB 阴性。两组患者在发病情况、主要动脉病变部位以及足部病变与供血动脉的分布关系方面具有可比性。12个月的总体LBP和AFS率分别为21.7%和39.1%,A组明显优于B组(LBP,31.6% vs 9.7%,p = 0.001;AFS,54.1% vs 22.2%,p = 0.006)。38名患者(55.1%)成功实现了血管造影剂直接流入足部,12个月的AFS率明显高于间接血管再通组(分别为54.8% vs 26.3%,p = 0.036),尽管直接血管再通组和间接血管再通组的12个月LBP率相当(分别为29% vs 15.8%,p = 0.133)。多变量逻辑回归分析发现,吸烟是大截肢的重要预测因素,而 WB 阳性和成功的直接血管再通则是肢体挽救的重要预测因素。WB 阳性可指导决定是否结束血管内手术,从而避免不必要的复杂操作以重新疏通更多血管。反之,如果 WB 为阴性,则表明需要进一步尝试血管再通,以增强伤口灌注和愈合。
{"title":"Can wound blush be used as an indicator for termination of endovascular procedures in chronic limb-threatening ischemia patients?","authors":"Mohammed Shahat, Ashraf G Taha, Ashraf Elnaggar, Hesham Aboloyoun","doi":"10.1177/17085381241283096","DOIUrl":"https://doi.org/10.1177/17085381241283096","url":null,"abstract":"IntroductionPredicting the outcomes of endovascular revascularization of chronic limb-threatening ischemia (CLTI) patients with foot wounds can be challenging. Angiographic wound blush (WB) assessment has been found to be a helpful tool to assess wound perfusion. The aim of this study is to evaluate WB during endovascular revascularization of CLTI patients and its effects on treatment outcomes.MethodsThis prospective study included all CLTI patients with foot wounds who underwent successful endovascular revascularization of infrainguinal arterial disease between 2019 and 2021. Patients were grouped according to the WB status into positive WB (group A) and negative WB (group B). Both groups were compared for demographics, comorbidities, clinical picture, and 12-month limb-based patency (LBP) and amputation-free survival (AFS) rates.ResultsThe study included 69 patients of Rutherford classes 5 (46.4%) and 6 (53.6%), with the main arterial lesion located at the femoropopliteal (58%) or infrapopliteal (42%) segments. Completion angiography showed positive WB in 38 (55.1%) patients and negative WB in 31 (44.9%) patients. Both groups were comparable regarding patient presentation, site of the main arterial lesion, and distribution of foot lesions in relation to the feeding artery. The overall 12-month LBP and AFS rates were 21.7% and 39.1%, respectively, with significantly better rates in group A than in group B (LBP, 31.6% vs 9.7%, p = 0.001 and AFS, 54.1% vs 22.2%, p = 0.006, respectively). Successful angiosome-based direct flow to the foot was achieved in 38 patients (55.1%), resulting in significantly better 12-month AFS rates than those with indirect revascularization (54.8% vs 26.3%, p = 0.036, respectively), despite the comparable 12-LBP rates between the direct and indirect revascularization groups (29% vs 15.8%, p = 0.133, respectively). Multivariate logistic regression analysis identified smoking as a significant predictor of a major amputation, whereas positive WB and successful direct revascularization were significant predictors of limb salvage.ConclusionsWB can serve as a predictor for AFS and LBP during endovascular revascularization of CLTI patients with foot wounds. A positive WB may guide the decision to conclude an endovascular procedure, potentially avoiding unnecessary complicated maneuvers to recanalize more vessels. Conversely, a negative WB may suggest the need for further revascularization attempts to augment wound perfusion and healing.","PeriodicalId":23549,"journal":{"name":"Vascular","volume":"15 1","pages":"17085381241283096"},"PeriodicalIF":1.1,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review of clinical guidelines and consensus statements concerning heparin and protamine dosing and monitoring of anticoagulation levels for non-cardiac arterial procedures. 系统回顾有关肝素和质胺剂量以及非心脏动脉手术抗凝水平监测的临床指南和共识声明。
IF 1.1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-10 DOI: 10.1177/17085381241283519
Liliane C Roosendaal,Orkun Doganer,Arno M Wiersema,Jan D Blankensteijn,Vincent Jongkind
OBJECTIVESThis systematic review was performed to examine all published practice Guidelines and Consensus Statements (together: GCS) on heparin dosing and monitoring during non-cardiac arterial procedures (NCAP). The objective was to scrutinize the recommendations and advice outlined within these GCS documents and to evaluate the supporting evidence for these recommendations. Additionally, the use of the activated clotting time (ACT) and target ACT values were explored.METHODSThis systematic review was performed in accordance with the PRISMA Guidelines. Medline and Embase databases were searched to identify all GCSs in the English language on NCAP. The final literature search was performed in January 2023. This search was supplemented by searching websites of relevant professional vascular surgical organizations for GCSs. Titles and abstracts were assessed by two independent reviewers.RESULTSOf 9716 titles identified, 27 GCSs met the predefined inclusion criteria: six GCSs regarding carotid intervention, seven regarding procedures for aneurysmal disease of the abdominal aorta and iliac arteries, 12 regarding interventions for acute and chronic peripheral arterial occlusive disease and two regarding open and endovascular interventions of thoraco-abdominal aortic aneurysms. Administration of heparin is advised for al NCAP. There was high variability concerning heparin dose: both standard dose as weight based dosing (30-150 IU/kg) was advised. Recommendations on repeated doses, ACT monitoring and heparin reversal using protamine also varied widely. In none of the GCSs, the type of the ACT measuring device or used cartridges were specified.CONCLUSIONSLarge variability was found between the included GCSs with regard to the recommendations on heparin dose and target ACT values during NCAP. Advice and recommendations in GCSs were based on low-quality studies or without providing any reference at all. The described variability in recommendations emphasizes the need for large prospective (randomized) studies or the incorporation of data on heparin and the use of ACT monitoring into verified vascular surgery registries, to develop evidence-based, practical and uniform applicable recommendations.
目的:本系统性综述研究了所有已出版的关于非心脏动脉手术 (NCAP) 期间肝素剂量和监测的实践指南和共识声明(合称 GCS)。目的是仔细研究这些 GCS 文件中概述的建议和意见,并评估这些建议的支持证据。此外,还探讨了活化凝血时间 (ACT) 和目标 ACT 值的使用。方法本系统性综述按照 PRISMA 指南进行。对 Medline 和 Embase 数据库进行了检索,以确定关于 NCAP 的所有英文 GCS。最终文献检索于 2023 年 1 月完成。此外,还在相关专业血管外科组织的网站上搜索了 GCS,作为对该搜索的补充。结果 在确定的 9716 篇文献中,有 27 篇 GCS 符合预定义的纳入标准:6 篇 GCS 涉及颈动脉介入治疗,7 篇涉及腹主动脉和髂动脉动脉瘤性疾病的手术,12 篇涉及急性和慢性外周动脉闭塞性疾病的介入治疗,2 篇涉及胸腹主动脉瘤的开放式和血管内介入治疗。建议在所有 NCAP 中使用肝素。肝素剂量的差异很大:既有标准剂量,也有基于体重的剂量(30-150 IU/kg)。关于重复剂量、ACT 监测和使用质胺逆转肝素的建议也大相径庭。结论所纳入的 GCS 中,关于 NCAP 期间肝素剂量和 ACT 目标值的建议存在很大差异。GCS 中的建议和推荐基于低质量的研究或根本没有提供任何参考。上述建议中的差异强调,需要开展大型前瞻性(随机)研究,或将肝素和 ACT 监测数据纳入经核实的血管外科登记册,以制定循证、实用和统一适用的建议。
{"title":"Systematic review of clinical guidelines and consensus statements concerning heparin and protamine dosing and monitoring of anticoagulation levels for non-cardiac arterial procedures.","authors":"Liliane C Roosendaal,Orkun Doganer,Arno M Wiersema,Jan D Blankensteijn,Vincent Jongkind","doi":"10.1177/17085381241283519","DOIUrl":"https://doi.org/10.1177/17085381241283519","url":null,"abstract":"OBJECTIVESThis systematic review was performed to examine all published practice Guidelines and Consensus Statements (together: GCS) on heparin dosing and monitoring during non-cardiac arterial procedures (NCAP). The objective was to scrutinize the recommendations and advice outlined within these GCS documents and to evaluate the supporting evidence for these recommendations. Additionally, the use of the activated clotting time (ACT) and target ACT values were explored.METHODSThis systematic review was performed in accordance with the PRISMA Guidelines. Medline and Embase databases were searched to identify all GCSs in the English language on NCAP. The final literature search was performed in January 2023. This search was supplemented by searching websites of relevant professional vascular surgical organizations for GCSs. Titles and abstracts were assessed by two independent reviewers.RESULTSOf 9716 titles identified, 27 GCSs met the predefined inclusion criteria: six GCSs regarding carotid intervention, seven regarding procedures for aneurysmal disease of the abdominal aorta and iliac arteries, 12 regarding interventions for acute and chronic peripheral arterial occlusive disease and two regarding open and endovascular interventions of thoraco-abdominal aortic aneurysms. Administration of heparin is advised for al NCAP. There was high variability concerning heparin dose: both standard dose as weight based dosing (30-150 IU/kg) was advised. Recommendations on repeated doses, ACT monitoring and heparin reversal using protamine also varied widely. In none of the GCSs, the type of the ACT measuring device or used cartridges were specified.CONCLUSIONSLarge variability was found between the included GCSs with regard to the recommendations on heparin dose and target ACT values during NCAP. Advice and recommendations in GCSs were based on low-quality studies or without providing any reference at all. The described variability in recommendations emphasizes the need for large prospective (randomized) studies or the incorporation of data on heparin and the use of ACT monitoring into verified vascular surgery registries, to develop evidence-based, practical and uniform applicable recommendations.","PeriodicalId":23549,"journal":{"name":"Vascular","volume":"13 1","pages":"17085381241283519"},"PeriodicalIF":1.1,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative outcomes between cryopreserved cadaveric saphenous vein and spliced autogenous vein for infrainguinal bypass 冷冻保存的尸体大隐静脉与拼接自体静脉用于腹股沟下搭桥术的效果比较
IF 1.1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-09 DOI: 10.1177/17085381241283123
Christopher Montoya, Fang Yuan, Lea Tordjman, Akashara Challa, Christopher Chow, Naixin Kang, Tony Shao, Stefan Kenel-Pierre, Jorge Rey, Arash Bornak
ObjectiveCryopreserved greater saphenous vein (CV) and spliced autogenous veins (SV) serve as alternative conduits for lower extremity revascularization when a single-segment autogenous saphenous vein is not available. This study compares the outcomes of infrainguinal bypasses using CV and two-segment SV as conduits.MethodsWe conducted a retrospective review of data on all lower extremity bypasses performed using CV or SV at our institution. Patients undergoing revascularization for atherosclerotic occlusive disease were included in the statistical analysis, while those with primary acute embolic and/or traumatic causes were excluded. Primary outcomes included limb loss. Secondary outcomes included primary, primary assisted, and secondary patency at one and 3 years.Results56 patients were included in the analysis, 25 had CV bypass and 31 had SV. The groups did not significantly differ in demographics and comorbidities except for age (mean age 68 CV vs 62 SV, p = .03), and prior coronary artery bypass graft (32% CV vs 6.5% SV, p = .01). There was no statistically significant difference between CV and SV at one- and three-years in limb salvage (54.4% CV vs 61.7% SV, p = .96 and 48.3% CV vs 50.2% SV, p = .94), and bypass abandonment (44.2% CV vs 61.7% SV, p = .83 and 44.2% CV vs 44% SV, p = .85). Despite lower one and 3-year primary patency for CV compared to SV (33.3% CV vs 54.9% SV, p = .29, and 27.7% CV vs 48% SV, p = .27), the difference was statistically not significant. CV and SV had also similar one and 3-year primary assisted (41.8% CV vs 57.8% SV, p = .72 and 41.8% CV vs 44.9% SV, p = .71), and secondary patency (43.9% CV vs 61.7% SV, p = .8 and 43.9% CV vs 44% SV, p = .88), with no statistically significant difference.ConclusionIn patients for whom single-segment autologous saphenous vein bypass is not an option, CV and SV show comparable limb salvage up to 3 years. SV may be a more durable option with higher patency, this was however not statistically significant in our cohort likely due to sample size.
目的当没有单段自体大隐静脉时,冷冻保存的大隐静脉(CV)和拼接的自体静脉(SV)可作为下肢血管再通术的替代导管。本研究比较了使用 CV 和双节段 SV 作为导管进行腹股沟下旁路手术的结果。方法我们对本机构所有使用 CV 或 SV 进行下肢旁路手术的数据进行了回顾性回顾。因动脉粥样硬化性闭塞症而接受血管再通手术的患者被纳入统计分析范围,而原发性急性栓塞和/或创伤性原因导致的患者则被排除在外。主要结果包括肢体缺失。次要结果包括1年和3年后的主要、主要辅助和次要通畅率。结果56名患者被纳入分析,其中25人进行了CV搭桥,31人进行了SV搭桥。除年龄(平均年龄 68 CV vs 62 SV,P = .03)和既往冠状动脉搭桥术(32% CV vs 6.5% SV,P = .01)外,两组在人口统计学和合并症方面无明显差异。在一年和三年的肢体挽救率(54.4% CV vs 61.7% SV,p = .96;48.3% CV vs 50.2% SV,p = .94)和放弃搭桥手术率(44.2% CV vs 61.7% SV,p = .83;44.2% CV vs 44% SV,p = .85)方面,CV 和 SV 之间的差异无统计学意义。尽管与 SV 相比,CV 的 1 年和 3 年初次通畅率较低(33.3% CV vs 54.9% SV,p = .29;27.7% CV vs 48% SV,p = .27),但在统计学上差异并不显著。CV和SV的1年和3年初次辅助率(41.8% CV vs 57.8% SV,p = .72;41.8% CV vs 44.9% SV,p = .71)和二次通畅率(43.9% CV vs 61.7% SV,p = .8;43.9% CV vs 44% SV,p = .88)也相似,差异无统计学意义。SV 可能是一种更耐用、通畅率更高的选择,但在我们的队列中,可能由于样本量的原因,这一点在统计学上并不显著。
{"title":"Comparative outcomes between cryopreserved cadaveric saphenous vein and spliced autogenous vein for infrainguinal bypass","authors":"Christopher Montoya, Fang Yuan, Lea Tordjman, Akashara Challa, Christopher Chow, Naixin Kang, Tony Shao, Stefan Kenel-Pierre, Jorge Rey, Arash Bornak","doi":"10.1177/17085381241283123","DOIUrl":"https://doi.org/10.1177/17085381241283123","url":null,"abstract":"ObjectiveCryopreserved greater saphenous vein (CV) and spliced autogenous veins (SV) serve as alternative conduits for lower extremity revascularization when a single-segment autogenous saphenous vein is not available. This study compares the outcomes of infrainguinal bypasses using CV and two-segment SV as conduits.MethodsWe conducted a retrospective review of data on all lower extremity bypasses performed using CV or SV at our institution. Patients undergoing revascularization for atherosclerotic occlusive disease were included in the statistical analysis, while those with primary acute embolic and/or traumatic causes were excluded. Primary outcomes included limb loss. Secondary outcomes included primary, primary assisted, and secondary patency at one and 3 years.Results56 patients were included in the analysis, 25 had CV bypass and 31 had SV. The groups did not significantly differ in demographics and comorbidities except for age (mean age 68 CV vs 62 SV, p = .03), and prior coronary artery bypass graft (32% CV vs 6.5% SV, p = .01). There was no statistically significant difference between CV and SV at one- and three-years in limb salvage (54.4% CV vs 61.7% SV, p = .96 and 48.3% CV vs 50.2% SV, p = .94), and bypass abandonment (44.2% CV vs 61.7% SV, p = .83 and 44.2% CV vs 44% SV, p = .85). Despite lower one and 3-year primary patency for CV compared to SV (33.3% CV vs 54.9% SV, p = .29, and 27.7% CV vs 48% SV, p = .27), the difference was statistically not significant. CV and SV had also similar one and 3-year primary assisted (41.8% CV vs 57.8% SV, p = .72 and 41.8% CV vs 44.9% SV, p = .71), and secondary patency (43.9% CV vs 61.7% SV, p = .8 and 43.9% CV vs 44% SV, p = .88), with no statistically significant difference.ConclusionIn patients for whom single-segment autologous saphenous vein bypass is not an option, CV and SV show comparable limb salvage up to 3 years. SV may be a more durable option with higher patency, this was however not statistically significant in our cohort likely due to sample size.","PeriodicalId":23549,"journal":{"name":"Vascular","volume":"2022 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Female gender is independently associated with longer hospital stays following infra-inguinal bypass for peripheral arterial disease. A retrospective cohort study. 女性性别与外周动脉疾病腹股沟下搭桥术后较长的住院时间密切相关。一项回顾性队列研究。
IF 1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-09-05 DOI: 10.1177/17085381241281315
Daniel J Farndon, Sri Vulla, Philip C Bennett
<p><strong>Aims: </strong>The association between gender and length of hospital stay following infra-inguinal bypass (IIB) surgery is unclear. While previous studies have reported gender disparities in length of hospital stay (LoS), the results are conflicting and could be attributable to other confounding factors. We undertook this cohort study to determine if there are any gender differences in length of hospital stay following infra-inguinal bypass for PAD after adjusting for well-known confounders.</p><p><strong>Methods: </strong>A 3-year single-centre retrospective case notes analysis of all people undergoing IIB between 2017 and 2019. Rutherford stage, graft conduit, urgency of bypass, level of bypass, procedure details, baseline demographics, length of stay (LoS) and co-morbidities were collected and univariable associations with length of hospital stay were reported. Factors associated with increased LoS on univariable analysis were entered into a multivariable model.</p><p><strong>Results: </strong>177 IIB were analysed with a median age of 70 [63-73] years, 124 (70.1%) were male and 89 (50.2%) had DM. A total of 78 (44.1%) were current smokers, and 100 (56.5%) underwent emergency procedures. The cohort included patients with Rutherford stage 3 (<i>n</i> = 41 (23.2%)), stage 4 (<i>n</i> = 48 (27.1%)), stage 5 (<i>n</i> = 86 (48.6%)) and stage 6 (<i>n</i> = 1 (0.6%)) disease. A total of 100 (56.5%) underwent emergency procedures. The conduits used were prosthetic (<i>n</i> = 62 (35%)), vein (<i>n</i> = 113 (63.8%)) and composite (<i>n</i> = 2 (1.1%)), and the level of distal anastomosis was above knee (<i>n</i> = 49 (27.7%)), below knee (<i>n</i> = 66 (37.3%)) and distal (<i>n</i> = 62 (35%). Baseline demographics did not differ by gender, and there were no differences in post-operative complications. The proportion of patients discharged to their usual place of residence without a package of care did not differ by gender (<i>p</i> = .387). However, length of stay for female patients was significantly longer than for male patients (9 [6-21] vs 7 [5-14] days, <i>p</i> = .021). Other factors associated with increased LoS on univariable analysis were emergency versus elective (<i>p</i> < .0001), Rutherford stage (<i>p</i> < .0001), bypass level (<i>p</i> = .001), bypass conduit (<i>p</i> = .001), post-operative complications (<i>p</i> < .0001) and discharge to rehab or home with package of care (<i>p</i> < .0001). Patients operated on by a female surgeon also had a longer hospital stay (14 [8-20] vs 7 [5-14], <i>p</i> = .011) than those operated on by a male surgeon. After multivariate adjustment for bypass urgency, level and conduit, Rutherford stage, presence of post-operative complications and discharge destination, female gender (RR 1.59 95% CI: 1.09-2.3, <i>p</i> = .017) was still associated with increased length of hospital stay.</p><p><strong>Conclusions: </strong>Even after adjustment for well-known factors associated with length of
目的:性别与腹股沟下搭桥术(IIB)术后住院时间的关系尚不清楚。虽然之前的研究报告了住院时间(LoS)方面的性别差异,但结果并不一致,而且可能与其他混杂因素有关。我们进行了这项队列研究,以确定在调整了众所周知的混杂因素后,腹股沟下搭桥术治疗 PAD 的住院时间是否存在性别差异:对2017年至2019年期间所有接受IIB手术的患者进行为期3年的单中心回顾性病例记录分析。收集了卢瑟福分期、移植物导管、搭桥紧迫性、搭桥水平、手术细节、基线人口统计学、住院时间(LoS)和并发症,并报告了与住院时间的单变量关联。将单变量分析中与住院时间延长相关的因素纳入多变量模型:分析了 177 例 IIB,中位年龄为 70 [63-73] 岁,124 例(70.1%)为男性,89 例(50.2%)患有糖尿病。78人(44.1%)目前吸烟,100人(56.5%)接受了急诊手术。队列中包括卢瑟福3期(41人(23.2%))、4期(48人(27.1%))、5期(86人(48.6%))和6期(1人(0.6%))患者。共有 100 人(56.5%)接受了急诊手术。使用的导管有人工导管(62 例(35%))、静脉导管(113 例(63.8%))和复合导管(2 例(1.1%)),远端吻合的水平有膝上吻合(49 例(27.7%))、膝下吻合(66 例(37.3%))和远端吻合(62 例(35%))。基线人口统计学无性别差异,术后并发症也无差异。患者出院后返回常住地而未接受一揽子护理的比例没有性别差异(p = .387)。不过,女性患者的住院时间明显长于男性患者(9 [6-21] 天 vs 7 [5-14] 天,p = .021)。在单变量分析中,与住院时间延长相关的其他因素包括急诊与择期手术(p < .0001)、卢瑟福分期(p < .0001)、分流水平(p = .001)、分流导管(p = .001)、术后并发症(p < .0001)以及出院后康复或在家接受一揽子护理(p < .0001)。与男外科医生相比,女外科医生手术的患者住院时间更长(14 [8-20] vs 7 [5-14],p = .011)。在对旁路手术的紧迫性、水平和导管、卢瑟福分期、术后并发症的存在和出院目的地进行多变量调整后,女性(RR 1.59 95% CI:1.09-2.3,p = .017)仍与住院时间的延长有关:结论:即使调整了众所周知的与住院时间相关的因素,女性似乎仍与住院时间明显延长有关。对影响性别差异因素的进一步调查可以进一步揭示这种明显的差异。
{"title":"Female gender is independently associated with longer hospital stays following infra-inguinal bypass for peripheral arterial disease. A retrospective cohort study.","authors":"Daniel J Farndon, Sri Vulla, Philip C Bennett","doi":"10.1177/17085381241281315","DOIUrl":"https://doi.org/10.1177/17085381241281315","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aims: &lt;/strong&gt;The association between gender and length of hospital stay following infra-inguinal bypass (IIB) surgery is unclear. While previous studies have reported gender disparities in length of hospital stay (LoS), the results are conflicting and could be attributable to other confounding factors. We undertook this cohort study to determine if there are any gender differences in length of hospital stay following infra-inguinal bypass for PAD after adjusting for well-known confounders.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A 3-year single-centre retrospective case notes analysis of all people undergoing IIB between 2017 and 2019. Rutherford stage, graft conduit, urgency of bypass, level of bypass, procedure details, baseline demographics, length of stay (LoS) and co-morbidities were collected and univariable associations with length of hospital stay were reported. Factors associated with increased LoS on univariable analysis were entered into a multivariable model.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;177 IIB were analysed with a median age of 70 [63-73] years, 124 (70.1%) were male and 89 (50.2%) had DM. A total of 78 (44.1%) were current smokers, and 100 (56.5%) underwent emergency procedures. The cohort included patients with Rutherford stage 3 (&lt;i&gt;n&lt;/i&gt; = 41 (23.2%)), stage 4 (&lt;i&gt;n&lt;/i&gt; = 48 (27.1%)), stage 5 (&lt;i&gt;n&lt;/i&gt; = 86 (48.6%)) and stage 6 (&lt;i&gt;n&lt;/i&gt; = 1 (0.6%)) disease. A total of 100 (56.5%) underwent emergency procedures. The conduits used were prosthetic (&lt;i&gt;n&lt;/i&gt; = 62 (35%)), vein (&lt;i&gt;n&lt;/i&gt; = 113 (63.8%)) and composite (&lt;i&gt;n&lt;/i&gt; = 2 (1.1%)), and the level of distal anastomosis was above knee (&lt;i&gt;n&lt;/i&gt; = 49 (27.7%)), below knee (&lt;i&gt;n&lt;/i&gt; = 66 (37.3%)) and distal (&lt;i&gt;n&lt;/i&gt; = 62 (35%). Baseline demographics did not differ by gender, and there were no differences in post-operative complications. The proportion of patients discharged to their usual place of residence without a package of care did not differ by gender (&lt;i&gt;p&lt;/i&gt; = .387). However, length of stay for female patients was significantly longer than for male patients (9 [6-21] vs 7 [5-14] days, &lt;i&gt;p&lt;/i&gt; = .021). Other factors associated with increased LoS on univariable analysis were emergency versus elective (&lt;i&gt;p&lt;/i&gt; &lt; .0001), Rutherford stage (&lt;i&gt;p&lt;/i&gt; &lt; .0001), bypass level (&lt;i&gt;p&lt;/i&gt; = .001), bypass conduit (&lt;i&gt;p&lt;/i&gt; = .001), post-operative complications (&lt;i&gt;p&lt;/i&gt; &lt; .0001) and discharge to rehab or home with package of care (&lt;i&gt;p&lt;/i&gt; &lt; .0001). Patients operated on by a female surgeon also had a longer hospital stay (14 [8-20] vs 7 [5-14], &lt;i&gt;p&lt;/i&gt; = .011) than those operated on by a male surgeon. After multivariate adjustment for bypass urgency, level and conduit, Rutherford stage, presence of post-operative complications and discharge destination, female gender (RR 1.59 95% CI: 1.09-2.3, &lt;i&gt;p&lt;/i&gt; = .017) was still associated with increased length of hospital stay.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Even after adjustment for well-known factors associated with length of ","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381241281315"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Axillary compared to brachial access for endovascular procedures. 用于血管内手术的腋窝入路与肱动脉入路的比较。
IF 1 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-08-30 DOI: 10.1177/17085381241279142
Mustafa A Altaha, Shawn Bailey, Sebastian Mafeld, Arash Jaberi, Kong Teng Tan

Objectives: Limited knowledge exists regarding access site complication rates between trans-axillary and trans-brachial approaches with sheath sizes ≥6Fr. We retrospectively reviewed our institution experience with access site complications for percutaneous trans-axillary and trans-brachial arterial interventions using sheath sizes ranging from 6Fr to 10Fr.

Methods: We examined 67 endovascular interventions performed over 18 months, restricted to sheath sizes of 6Fr to 10Fr. Procedures utilizing trans-brachial (41 cases) and trans-axillary (26 cases) approaches under sonographic guidance were included. Cases involving hemodialysis accesses and those requiring surgical cut-down were excluded. The primary outcome measure was the occurrence of major access site complications (SIR grade-II/III) within 30 days, with data collected on hemostasis method, sheath size, and complications. Statistical analysis involved ANCOVA and Fisher's exact tests, with significance set at p < .05.

Results: Successful percutaneous arterial access was achieved in all cases using either approach (trans-axillary or trans-brachial). Closure devices were employed in all axillary punctures and in 71% of brachial punctures. Major access site complications occurred in 7 out of 41 cases (17%) in the trans-brachial group and in 4 out of 26 cases (15%) in the trans-axillary group. However, there was no statistically significant difference in complication rates between the two groups, regardless of access site or sheath size.

Conclusion: Trans-axillary access serves as a safe and effective upper limb access method for percutaneous endovascular procedures requiring sheath size of 7Fr or larger when compared to trans-brachial approach.

目的:关于经腋窝和经肱骨入路、鞘管尺寸≥6Fr的入路部位并发症发生率的知识有限。 我们回顾性地总结了本院使用6Fr至10Fr尺寸的鞘管进行经皮经腋窝和经肱骨动脉介入治疗的入路部位并发症的经验:我们对 18 个月内实施的 67 例血管内介入手术进行了检查,这些手术仅限于 6Fr 至 10Fr 的鞘,包括在超声引导下使用经腋窝(41 例)和经腋窝(26 例)入路的手术。涉及血液透析通路和需要手术切开的病例除外。主要结果指标是 30 天内主要通路部位并发症的发生率(SIR 二级/三级),并收集止血方法、鞘大小和并发症的数据。统计分析包括方差分析和费雪精确检验,显著性以 p < .05 为标准:结果:采用经腋窝或经肱骨两种方法的所有病例均成功实现了经皮动脉入路。所有腋窝穿刺和 71% 的肱动脉穿刺都使用了闭合装置。经肱骨组的 41 例病例中有 7 例(17%)出现主要穿刺部位并发症,经腋窝组的 26 例病例中有 4 例(15%)出现主要穿刺部位并发症。然而,无论入路部位或鞘的大小如何,两组的并发症发生率在统计学上没有显著差异:结论:与经腋窝入路相比,经腋窝入路是一种安全有效的上肢入路方法,适用于需要7Fr或更大尺寸鞘管的经皮血管内手术。
{"title":"Axillary compared to brachial access for endovascular procedures.","authors":"Mustafa A Altaha, Shawn Bailey, Sebastian Mafeld, Arash Jaberi, Kong Teng Tan","doi":"10.1177/17085381241279142","DOIUrl":"https://doi.org/10.1177/17085381241279142","url":null,"abstract":"<p><strong>Objectives: </strong>Limited knowledge exists regarding access site complication rates between trans-axillary and trans-brachial approaches with sheath sizes ≥6Fr. We retrospectively reviewed our institution experience with access site complications for percutaneous trans-axillary and trans-brachial arterial interventions using sheath sizes ranging from 6Fr to 10Fr.</p><p><strong>Methods: </strong>We examined 67 endovascular interventions performed over 18 months, restricted to sheath sizes of 6Fr to 10Fr. Procedures utilizing trans-brachial (41 cases) and trans-axillary (26 cases) approaches under sonographic guidance were included. Cases involving hemodialysis accesses and those requiring surgical cut-down were excluded. The primary outcome measure was the occurrence of major access site complications (SIR grade-II/III) within 30 days, with data collected on hemostasis method, sheath size, and complications. Statistical analysis involved ANCOVA and Fisher's exact tests, with significance set at <i>p</i> < .05.</p><p><strong>Results: </strong>Successful percutaneous arterial access was achieved in all cases using either approach (trans-axillary or trans-brachial). Closure devices were employed in all axillary punctures and in 71% of brachial punctures. Major access site complications occurred in 7 out of 41 cases (17%) in the trans-brachial group and in 4 out of 26 cases (15%) in the trans-axillary group. However, there was no statistically significant difference in complication rates between the two groups, regardless of access site or sheath size.</p><p><strong>Conclusion: </strong>Trans-axillary access serves as a safe and effective upper limb access method for percutaneous endovascular procedures requiring sheath size of 7Fr or larger when compared to trans-brachial approach.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381241279142"},"PeriodicalIF":1.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Vascular
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1