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Developing solutions roadmaps for rice production in flooding area of the Vietnamese Mekong Delta adapting to uncertain changes in climate and surface water resources 制定越南湄公河三角洲洪涝地区水稻生产的解决方案路线图,以适应气候和地表水资源的不确定变化
Pub Date : 2023-04-17 DOI: 10.15625/2525-2518/16432
H. Hoang, Nguyen Hong Tin, Dinh Diep Anh Tuan, Van Pham Dang Tri
Climate change, hydro-power dams and socio-economic development in the upper Mekong River, have caused changes in surface water resources and agricultural transformation in the Vietnamese Mekong Delta (VMD). It is unpredictable and influences decision-making processes on water resource management. This study aims at applying the DAPP (Dynamic Adaptive Policy Pathways) approach to develop solution roadmaps supporting rice production in the Mekong Delta projection to 2030 under the context of uncertain changes on surface water resources. Data were collected from local officers, farmers, experts at Can Tho University, Technical University Delft, and Utrecht University using semi-structured interview techniques including workshops, group discussions, and in-depth interviews. The consolidated solutions from stakeholder’s opinions were evaluated at different socio-economic and environmental dimensions, specially focused on the time of tipping point of each solution. The study results show that two solution roadmaps were developed as sample scenarios to promote rice production in the upper area of the VMD. The determination of the solutions roadmaps based on the agreement of the stakeholders, which is a new feature of this approach in linking many stakeholders for the general development of the region. The DAPP approach could be suitable to support decision-making on surface water resources management in the context of uncertain changes. Therefore, further studies can apply this approach to other regions in the VMD which will support to reinforce and demonstrate the applicability of the DAPP approach on supporting decision-making in the face of increasingly uncertain changes in the VMD.
气候变化、水电大坝和湄公河上游的社会经济发展导致了越南湄公河三角洲地表水资源的变化和农业转型。它是不可预测的,影响着水资源管理的决策过程。本研究旨在应用动态适应政策路径(DAPP)方法,在地表水资源不确定变化的背景下,制定支持湄公河三角洲到2030年水稻生产预测的解决方案路线图。数据收集自当地官员、农民、芹苴大学、代尔夫特工业大学和乌得勒支大学的专家,采用半结构化访谈技术,包括研讨会、小组讨论和深度访谈。从不同的社会经济和环境维度对利益相关者意见的综合解决方案进行评估,特别关注每个解决方案的临界点时间。研究结果表明,制定了两种解决方案路线图作为样例场景,以促进VMD上部地区的水稻生产。根据利益相关者的协议确定解决方案路线图,这是该方法的新特点,将许多利益相关者联系起来,促进该地区的总体发展。DAPP方法可适用于支持不确定变化背景下的地表水资源管理决策。因此,进一步的研究可以将该方法应用于VMD的其他区域,这将有助于加强和证明DAPP方法在面对越来越不确定的VMD变化时支持决策的适用性。
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引用次数: 0
Green synthesis of graphene quantum dots from rice flour 用米粉绿色合成石墨烯量子点
Pub Date : 2023-04-17 DOI: 10.15625/2525-2518/16847
Quyen, Thi Bich Tran, Phuong Thi Ngoe Huynh, My, Nguyen Tra Ngo, Thien, Van Hong Doan, T. H. Luong, L. Tran
Graphene Quantum Dots (GQDs) were successfully synthesized by a green and eco-friendly synthetic method using abundant and naturally available raw materials from rice flour. This study suggested and compared two aggressive approaches to fabricate GQDs, which are hydrothermal method at 170 °C for 8 h and microwave irradiation method at 900 W with a short reaction time of 30 min. The results showed that the hydrothermal method produced GQDs with better nanoparticle size and properties than the microwave irradiation method. Furthermore, the products were only GQDs, water and carbide precipitate, thus avoiding complicated post-processing steps. The synthesized GQDs were determined for their morphology by Transmission electron microscope (TEM) showing spherical nanoparticles with an average size of ~5-7 nm and ~10-14 nm for hydrothermal and microwave irradiation methods, respectively. Besides, these GQDs were also analyzed for their characterizations, morphologies and compositions by UV-vis, XRD and FTIR. Thanks to their low cytotoxicity, good optical stability, and excellent photo-luminescence property, GQDs have become novel nanostructured materials in many application fields from energy to biomedicine and environment such as sensors, bio-imaging, drug carriers, and solar cells.
石墨烯量子点(GQDs)是一种绿色环保的合成方法,利用丰富的天然原料从米粉中合成的。本研究提出并比较了两种制备GQDs的方法,即水热法在170°C下反应8 h和微波辐照法在900 W下反应30 min。结果表明,水热法制备的GQDs具有更好的纳米颗粒大小和性能。此外,产物仅为GQDs、水和碳化物沉淀,从而避免了复杂的后处理步骤。通过透射电子显微镜(TEM)对合成的GQDs形貌进行了表征,水热法和微波法制备的GQDs的平均粒径分别为~5 ~ 7 nm和~10 ~ 14 nm。此外,利用UV-vis、XRD和FTIR对这些GQDs进行了表征、形貌和组成分析。由于其低细胞毒性、良好的光学稳定性和优异的光致发光性能,GQDs已成为从能源到生物医学和环境的许多应用领域的新型纳米结构材料,如传感器、生物成像、药物载体和太阳能电池。
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引用次数: 0
Synthesis and cytotoxic activity of some novel 2’-hydroxychalcones containing murrayafoline A 几种新型2′-羟查尔酮的合成及细胞毒活性研究
Pub Date : 2023-04-17 DOI: 10.15625/2525-2518/16785
Le Duc Anh, Luu Van Chinh, Truong Ngoc Hung, Nguyen Manh Cuong, Pham Hong Ngoc
2’-Hydroxychalcones and murrayafoline A, a natural compounds isolated from Glycomis stenocarpa, have been reported to have the promising anti-cancer activity. In this study, a series of 2'-hydroxychalcones containing murrayafoline A (MuA) 6a-f were achieved by Claisen-Schmidt condensation of the key intermediate 5'-(1-methoxy-3-methyl-carbazolyl)methyl-2'-hydroxyacetophenone 4 with various aldehydes 5a-f with purpose of combining activity of two precusors. Their structures were determined by NMR and MS spectral data. Screening for cytotoxicity of compounds showed that compounds 6a-6d expressed cytotoxic activity, notably compound 6a displayed activity against all tested cell lines LU-1, Hep-G2, MCF-7, P338, and SW480 with the IC50 values ranging from 23.97 to 80.19 μg/mL. Clearly, the substitution at position of N-H group of murrayafoline a led to a decline in the cytotoxicity of the obtained derivatives. This finding suggests the presence of the N-H group might be play a crucial role for the cytotoxicity of the murrayafoline A derivatives.
2′-羟基查尔酮和murrayafoline A是一种从窄果糖中分离得到的天然化合物,具有良好的抗癌活性。本研究通过关键中间体5′-(1-甲氧基-3-甲基-咔唑基)甲基-2′-羟基苯乙酮4与多种醛5a-f的Claisen-Schmidt缩合反应,获得了一系列含murrayafoline a (MuA) 6a-f的2′-羟基查尔酮,以达到两种前体的结合活性。通过核磁共振和质谱数据确定了它们的结构。化合物6a-6d均表现出细胞毒活性,其中化合物6a对所有细胞株LU-1、Hep-G2、MCF-7、P338和SW480均表现出活性,IC50值在23.97 ~ 80.19 μg/mL之间。显然,甲基亚酚a N-H基位置的取代导致所得到的衍生物的细胞毒性下降。这一发现表明N-H基团的存在可能在murrayafoline a衍生物的细胞毒性中起关键作用。
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引用次数: 0
Prediction of the Distribution and Effect of Diameters of the Cylinder and the Piston Post-Manufacture on the Operation of Gas-Operated Automatic Rifles 气控自动步枪枪筒直径和活塞直径的分布及其制造后对操作影响的预测
Pub Date : 2023-04-17 DOI: 10.15625/2525-2518/16627
N. Hung
The article is focused on the application of the reliability and experimental statistics theory to predict the distribution of the cylinder inner diameter and the piston outer diameter post-manufacture for the gas-operated automatic rifles. Besides, the influence of these dimensions on the operation of the automatic system was also studied in 5 cases with the maximum, minimum, and the most probable. The study object in the article is 7.62mm AKM-1 rifles. Research results show that the cylinder inner diameter and the piston outer diameter post-manufacture of  7.62mm AKM-1 rifles follow the normal distribution. The research results of the article can be used to establishing technical conditions for new gun acceptance post-manufacture.
本文主要研究了用可靠性和实验统计理论预测气控自动步枪生产后气缸内径和活塞外径分布的方法。此外,还从最大、最小和最可能的5种情况下研究了这些尺寸对自动化系统运行的影响。本文的研究对象为7.62mm AKM-1步枪。研究结果表明:7.62mm AKM-1步枪生产后筒体内径和活塞外径服从正态分布;本文的研究成果可为新炮的后期验收制定技术条件。
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引用次数: 0
Fabrication of polyglutamic acid-based sensor for electrochemical determination of a phenicol antibiotic in water environment 水环境中苯类抗生素电化学测定用聚谷氨酸传感器的制备
Pub Date : 2023-04-05 DOI: 10.15625/2525-2518/16865
Thi Tuyet Ngan Nguyen, Thi Thu Ha Vu, Van Thanh Dang, Tragiang Nguyen, Thi Hai Yen Pham
In this study, a graphite electrode (GrE) modified with polyglutamic acid was used to determine chloramphenicol (CAP), a phenicol antibiotic, in a water environment using adsorptive stripping linear sweep voltammetry. The pGA modification process involved electropolymerization via cyclic voltammetry, resulting in a significantly enlarged electrochemical active area of the pGA/GrE interface (1.5 times greater than that of the unmodified GrE). The highest CAP signal was obtained on the electrode fabricated by scanning 50 cycles in the potential range of -1.2 V to +2.0 V. The CAP signal recorded on the pGA/GrE electrode was nine times higher than that on the GrE, which was due to the larger electrochemical active area of the pGA/GrE and its good adsorption capacity with CAP. Analysis conditions including the pH of electrolyte and accumulation time, were optimized. Under optimal conditions, the calibration curve was built with two linear regions in the concentration ranges of 0.5-20 µmol L-1 (R2 = 0.987) and 20-100 µmol L-1 (R2 = 0.996), and the detection limit for CAP was 0.28 µmol L-1.
本研究采用聚谷氨酸修饰石墨电极(GrE),采用吸附溶出线性扫描伏安法测定水环境中氯霉素(CAP)的含量。pGA改性过程通过循环伏安法进行电聚合,导致pGA/GrE界面的电化学活性面积显著增大(比未改性的GrE大1.5倍)。在-1.2 V ~ +2.0 V的电位范围内扫描50次,得到了最高的CAP信号。pGA/GrE电极记录的CAP信号比GrE高9倍,这是由于pGA/GrE具有更大的电化学活性面积和良好的CAP吸附能力。优化了电解液pH和积累时间等分析条件。在最佳条件下,在0.5 ~ 20µmol L-1 (R2 = 0.987)和20 ~ 100µmol L-1 (R2 = 0.996)范围内建立了两个线性区域,CAP的检出限为0.28µmol L-1。
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引用次数: 0
Synthesis of highly stable silver nanoparticles as computed tomography contrast agents 合成高度稳定的银纳米颗粒作为计算机断层造影剂
Pub Date : 2023-04-05 DOI: 10.15625/2525-2518/16892
Tam The Le, Linh Nguyen Thi Ngoc
In this work, highly stable Ag nanoparticles solution was synthesized using TBAB to reduce Ag+ in the presence of OLA in organic solvents at room temperature, and poly(acrylic acid) (PAA) as a phase transfer ligand in organic solvents. The effects of different solvents on the morphology and properties of the Ag nanomaterials were investigated in detail. The products were characterized by using transmission electron microscopy (TEM), X-ray diffraction (XRD), and absorption spectroscopy. Structural analysis demonstrated that the Ag nanomaterials showed good crystallinity. We have successfully synthesized Ag nanoparticles (Ag NPs) with small particle size (6.1 - 7.3 nm), high uniformity in organic solvents at room temperature. The Ag NPs obtained after phase transformation with PAA are well dispersed, endurance and stability in aqueous solvents. The obtained in-vitro CT imaging results have good X-ray absorption value. These findings suggest the potential application of PAA-coated Ag nanoparticles in the biomedical field, especially in imaging diagnostics using CT computed tomography.  
在有机溶剂中,室温下,在OLA存在的情况下,利用TBAB还原Ag+,在有机溶剂中以聚丙烯酸(PAA)作为相转移配体,合成了高度稳定的Ag纳米颗粒溶液。研究了不同溶剂对银纳米材料形貌和性能的影响。采用透射电镜(TEM)、x射线衍射(XRD)和吸收光谱对产物进行了表征。结构分析表明,银纳米材料具有良好的结晶度。我们成功地在室温下合成了粒径小(6.1 - 7.3 nm)、均匀性高的银纳米颗粒(Ag NPs)。经PAA相变制备的Ag NPs在水溶液中分散性好,耐久性好,稳定性好。所获得的体外CT成像结果具有良好的x射线吸收价值。这些发现提示了paa包覆银纳米颗粒在生物医学领域的潜在应用,特别是在使用CT计算机断层成像诊断方面。
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引用次数: 0
In silico studies on potential MCF-7 inhibitors of alkaloid and phenolic compounds isolated from Zanthoxylum nitidum: A combination of molecular docking and ADMET analysis 从镍花椒中分离的生物碱和酚类化合物的潜在MCF-7抑制剂的硅研究:分子对接和ADMET分析的结合
Pub Date : 2023-04-05 DOI: 10.15625/2525-2518/16945
Q. Pham, Thi-Hong-Minh Pham
In this study, computational molecular simulation and drug-like properties assessment were used to gain insight into the binding ability of 16 alkaloid and phenolic compounds isolated from Zanthoxylum nitidum on protein tubulin. Amongst studied candidates, compounds 8 and 10 were identified as potential candidates for inhibiting the function of tubulin at the active site regarding binding affinity, dock pose and ADMET properties analysis. These findings shed light on the potential anti-cancer of compounds isolated from Zanthoxylum nitidum.
本研究通过计算分子模拟和类药物性质评估,深入研究了从花椒中分离的16种生物碱和酚类化合物与蛋白微管蛋白的结合能力。在研究的候选物中,化合物8和10被确定为抑制活性位点微管蛋白功能的潜在候选物,包括结合亲和力、码头姿态和ADMET性质分析。这些发现揭示了从黑花椒中分离的化合物的潜在抗癌作用。
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引用次数: 0
Synthesis, structure and antibacterial, antifungal activities of some hydrazones synthesized from 4-hydroxy-3-nitrobenzaldehyde 4-羟基-3-硝基苯甲醛合成的几种腙的合成、结构及抑菌抑菌活性
Pub Date : 2023-04-05 DOI: 10.15625/2525-2518/17073
Eight hydrazones 7a-h containing benzo[d]thiazole were synthesized in high yield by the condensation reaction of N-(5-(benzo[d]thiazol-2-yl)-2-(2-hydrazinyl-2-oxoethoxy)phenyl)acetamide (6) derived from 4-hydroxy-3-nitrobenzaldehyde with aromatic aldehydes under microwave irradiation. Structures of these derivatives 7a-h were elucidated by IR, NMR, and MS analysis. NMR spectra showed that in solution, hydrazones may exist in two conformations EN-C(O)ZN-C(O)EC=N and ZN-C(O)ZN-C(O)EC=N, the relative ratio of these two conformations is about 3:2. Four compounds 7a, 7c, 7e, 7g were screened for antimicrobial activities. Compounds 7c, 7e, and 7g exhibited weak antibacterial and antifungal activity against B. subtillis and S. cerevisiae, E. coli, or P. aeruginosa at 200 µg/L.
以4-羟基-3-硝基苯甲醛为原料,在微波辐射下,N-(5-(苯并[d]噻唑-2-基)-2-(2-肼基-2-氧乙氧基)苯基)乙酰胺(6)与芳香醛缩合反应,高收率合成了8个含苯并[d]噻唑的7a-h腙。这些衍生物7a-h的结构通过IR、NMR和MS分析得到了证实。核磁共振谱表明,在溶液中,腙以EN-C(O)ZN-C(O)EC=N和ZN-C(O)ZN-C(O)EC=N两种构象存在,两种构象的相对比例约为3:2。对化合物7a、7c、7e、7g进行抑菌活性筛选。在200µg/L浓度下,化合物7c、7e和7g对枯草芽孢杆菌、酿酒葡萄球菌、大肠杆菌和铜绿假单胞菌表现出较弱的抗菌和抗真菌活性。
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引用次数: 0
Bert Adapter and Contrastive Learning for Continual Classification of Aspect Sentiment Task Sequences 面向面向情感任务序列连续分类的Bert适配与对比学习
Pub Date : 2023-04-05 DOI: 10.15625/2525-2518/17395
Task incremental learning, a setting of Continual learning, isan approach to exploit the knowledge from previous tasks for currentlynew task. Task incremental learning aims to solve two big challengesof continual learning: catastrophic forgetting and knowledge transfer orsharing between previous tasks and current task. This paper improveTask incremental learning by (1) transferring the knowledge (not thetraining data) learned from previous tasks to a new task (contrast ofmulti-task learning); (2) to maintain or even improve performance oflearned models from previous tasks with avoid forgetting; (3) to developa continual learning model based on result from (1) and (2) to applyfor aspect sentiment classification. Specifically, we combine two loss baseon contrastive learning modules from Contrastive Knowledge Sharing(CKS) for encouraging knowledge sharing between old and current tasksand improve the performance of the current task by Contrastive Super-vised learning (CSC) module. The experimental results show that ourmethod could get rid of previous learned tasks catastrophic forgettingphenomenon and outperform the previous study for aspect sentimentclassification.
任务增量学习是一种持续学习的设置,是一种利用以前任务中的知识来完成当前新任务的方法。任务增量学习旨在解决持续学习的两大挑战:灾难性遗忘和前一任务与当前任务之间的知识转移或共享。本文通过(1)将从前一个任务中学习到的知识(不是训练数据)转移到一个新的任务(多任务学习的对比)来改进任务增量学习;(2)保持甚至提高从以前的任务中学习到的模型的性能,避免遗忘;(3)基于(1)和(2)的结果开发持续学习模型,应用于方面情感分类。具体来说,我们结合对比知识共享(对比Knowledge Sharing, CKS)的两个基于损失的对比学习模块,鼓励旧任务和当前任务之间的知识共享,并通过对比监督学习(contrast supervised learning, CSC)模块提高当前任务的性能。实验结果表明,该方法能够有效地消除以往学习任务的灾难性遗忘现象,在方面情感分类方面优于以往的研究。
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引用次数: 0
Study of corrosion behavior of arc thermal sprayed Al-Mg alloy coating 电弧热喷涂铝镁合金涂层的腐蚀行为研究
Pub Date : 2023-04-05 DOI: 10.15625/2525-2518/16768
In this study, Al-Mg alloy coatings were deposited on a C45 steel substrate by using the electric arc spray technique. The corrosion behavior of the coating was studied by electrochemical measurements and salt spray tests. The electrochemical tests were performed in 3.5 wt.% NaCl solution. Polarization tests indicated that the corrosion potential of the coating is significantly more negative than that of steel substrate after 240 hours of immersion. EIS measurements showed that after 24 hours of immersion, the total impedance increased with increasing the immersion time. This could be due to sealing of pores by corrosion products which hinder further penetration of the solution through the coating. Red rust spots did not appear on the surface of the coating after 1360 hours of salt spray test. The corrosion rate of the coating decreased with the increase in salt spray test time. After the salt spray test, the coating surface pitted and the cross section of the coating appeared with many long voids. In addition, XRD analysis proved that the main corrosion product was Al(OH)3. The results obtained indicated that arc thermal sprayed Al-Mg alloy coatings can reliably protect steel structures against corrosion in chloride-containing aqueous solutions.
本研究采用电弧喷涂技术在C45钢基体上沉积了铝镁合金涂层。通过电化学测试和盐雾试验研究了涂层的腐蚀行为。在3.5 wt.% NaCl溶液中进行电化学试验。极化试验结果表明,浸泡240 h后,涂层的腐蚀电位明显大于钢基体的腐蚀电位。EIS测试结果表明,浸泡24 h后,总阻抗随浸泡时间的增加而增大。这可能是由于腐蚀产物密封了孔隙,阻碍了溶液通过涂层的进一步渗透。盐雾试验1360小时后,涂层表面未出现红色锈斑。随着盐雾试验时间的延长,涂层的腐蚀速率逐渐降低。盐雾试验后,涂层表面出现麻点,涂层截面上出现许多长空洞。XRD分析表明,腐蚀产物主要为Al(OH)3。结果表明,电弧热喷涂铝镁合金涂层能可靠地保护钢结构在含氯化物水溶液中的腐蚀。
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引用次数: 0
期刊
Vietnam Journal of Science and Technology
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