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A Comparative Study on Safety and Efficacy of Caudal, Thoracic Epidural and Intra Venous Analgesia in Paediatric Cardiac Surgery: A Double Blind Randomised Trial 小儿心脏手术中尾侧、胸侧硬膜外和静脉内镇痛的安全性和有效性比较:一项双盲随机试验
Pub Date : 2020-07-06 DOI: 10.4236/wjcs.2020.107013
M. Vakamudi, Rajeshkumar Kodali, R. Karthekeyan, P. Thangavel, Kamalakannan Sambandham
Introduction:Regional anaesthesia combined with general anaesthesia reduces stress response to surgery, duration of ventilation, intensive care unit (ICU) stay and promotes early recovery. Studies on thoracic epidural, caudal analgesia along with general anaesthesia (GA) in paediatric cardiac surgery are limited hence we aimed to compare efficacy and safety of caudal, thoracic epidural and intravenous analgesia in paediatric cardiac surgery. Methodology: This study was conducted in the Department of Anaesthesiology in a tertiary care teaching hospital in southern India from February 2019 to December 2019. 90 children were randomised into group A, group B, group C. Children in group A received caudal analgesia along with GA. Group B children received thoracic epidural along with GA. Group C patients received intravenous analgesia along with GA. Rescue analgesia 1 mcg/kg fentanyl given in all 3 groups if pain score is more than 4. Primary outcome assessed was post-op pain scores. Secondary outcome assessed was duration of ventilation, duration of intensive care unit stay. Results: All patients were comparable in terms of age, sex, weight, mean RACHS score, baseline heart rate and blood pressure. Pain scores were significantly lower in thoracic epidural group compared to other two grou ps. Duration of ventilation was lower in thoracic epidural group (91.17± 43.85) minutes and caudal (199.6 ± 723.59) minutes compared to intravenous analgesia groups (436.37 ± 705.51) minutes. Duration of ICU stay was significantly low in thoracic epidural group (2.73 ± 0.69) days compared to caudal (3.7 ± 2.8) and intravenous analgesia groups (4.33 ± 0.920). We didn’t have any complications like hematoma, transient or permanent neurological sequelae in regional anesthesia groups. Conclusion: Regional anaesthesia along with general anaesthesia was more effective in pain relief than intravenous analgesia with general anaesthesia in paediatric cardiac surgery.
导读:区域麻醉与全身麻醉相结合可减少手术应激反应、通气时间、重症监护病房(ICU)住院时间,促进早期恢复。关于胸椎、胸椎硬膜外镇痛和全身麻醉在小儿心脏手术中的应用研究有限,因此我们旨在比较胸椎、胸椎硬膜外和静脉内镇痛在小儿心脏手术中的疗效和安全性。方法:本研究于2019年2月至2019年12月在印度南部一家三级护理教学医院的麻醉科进行。90例患儿随机分为A组、B组、c组。A组患儿在服用GA的同时给予尾侧镇痛。B组患儿行胸椎硬膜外加GA。C组患者在GA治疗的同时给予静脉镇痛。疼痛评分大于4时,三组均给予芬太尼1 mcg/kg抢救镇痛。评估的主要结局是术后疼痛评分。评估的次要结局是通气时间、重症监护病房住院时间。结果:所有患者在年龄、性别、体重、平均RACHS评分、基线心率和血压方面具有可比性。胸段硬膜外组疼痛评分明显低于其他两组,通气时间(91.17±43.85)min、尾段(199.6±723.59)min低于静脉镇痛组(436.37±705.51)min。胸段硬膜外组ICU住院时间(2.73±0.69)d明显低于尾段组(3.7±2.8)d和静脉镇痛组(4.33±0.920)d。在区域麻醉组中,我们没有任何并发症,如血肿,短暂或永久的神经系统后遗症。结论:在小儿心脏手术中,局部麻醉加全身麻醉比静脉麻醉加全身麻醉更能有效缓解疼痛。
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引用次数: 0
The Gerbode Defect: About 2 Cases Gerbode缺损:约2例
Pub Date : 2020-07-06 DOI: 10.4236/wjcs.2020.107014
Amine Majdoub, Anas Elhafidi, Cedric Mutuale, S. Boulmakoul, M. Messouak
Background: Left ventricular to right atrial communications (LV-RA) or the Gerbode defects are rare and complex types of ventricular septal defect. Their clinical diagnosis is not specific. However, the main clue to identifying Gerbode defect comes from Doppler-coupled echocardiography (TTE), and the treatment is mainly surgical. Aim: We hereby report our experience in surgical management of Gerbode defect through two exceptional congenital cases (type 1 and type 2 of Gerbode defect). Case Presentation: The diagnosis was established in adult patients, the first case is a 27-year-old woman who had dyspnea, and in whom the TTE revealed LV-RA communication, with repercussions on the right cavities. The second case is a 23-year-old man, with the concept of statutory weight delay, consulted for progressive dyspnea; the TTE initially revealed a very large perimembranous ventricular defect associated with significant pulmonary hypertension. Cardiopulmonary bypass surgery was done for a successful and complete correction. Conclusion: Gerbode defect is so rare; the diagnosis is made by TTE. And surgery must not be delayed until repercussion on right cavities and pulmonary hypertension.
背景:左室至右房通(LV-RA)或Gerbode缺损是一种少见且复杂的室间隔缺损类型。他们的临床诊断并不明确。然而,识别Gerbode缺陷的主要线索来自多普勒耦合超声心动图(TTE),治疗主要是手术。目的:通过两例特殊的先天性Gerbode缺损(1型和2型),报告手术治疗Gerbode缺损的经验。病例介绍:该诊断是在成年患者中建立的,第一个病例是一名27岁的女性,她有呼吸困难,TTE显示LV-RA通信,对右腔有影响。第二例为23岁男性,有法定体重延迟的概念,就诊进行性呼吸困难;TTE最初显示一个非常大的膜周围心室缺损,并伴有明显的肺动脉高压。体外循环手术是成功和完全纠正。结论:Gerbode缺损是罕见的;由TTE诊断。手术不能延迟,直到右腔和肺动脉高压的反应。
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引用次数: 1
A Case of Giant Mediastinal Liposarcoma of Thymic Origin: A Rare Clinical Entity 胸腺源性巨大纵隔脂肪肉瘤1例:罕见的临床病例
Pub Date : 2020-06-15 DOI: 10.4236/wjcs.2020.106010
Debmalya Saha, Pawan K Singh, R. Sharma, S. Naqvi, Saket Aggarwal, M. Geelani
Thymoliposarcoma is an exceedingly rare tumor of thymus with a very few cases reported till date. This case study presents a 45-year male with rare type of thymoma. On the contrast-enhanced CT images, there was a large mass lesion of predominantly fat attenuation in the pre-vascular compartment of the mediastinum insinuating on both sides of the visceral compartment of the mediastinum, and extending upto the bilateral cardio phrenic and anterior costophrenic angles, anterior to the right ventricle with loss of fat plane with the pericardium, with few sub-centimetric lymph nodes in the right paratracheal and AP window and a calcified right hilar lymph node, suggestive of well-differentiated liposarcoma/thymoliposarcoma. Initial CT guided tru-cut tissue biopsy was inconclusive, and the repeat biopsy revealed as fibro-collagenous tissue with area of necrosis, focal myxoid changes in the background with presence of cells which are spindle to oval in shape with mild nuclear pleomorphism and negative for S100, Cytokeratin, CD34, desmin. The entire tumor was resected en masse after meticulous dissection without the support of cardiopulmonary bypass (CPB) with an intact pericardium. Final histopathology report of the surgical biopsy specimens is consistent with dedifferentiated thymoliposarcoma with focal ganglionic cell differentiation. Postoperative follow-up CECT of thorax revealed no evidence of residual mass in the pre-vascular compartment. The patient is disease-free and asymptomatic after 6-month and he is under routine follow-up under Radiotherapy department since he received 30 Gy of postoperative radiotherapy (PORT).
胸腺肉瘤是一种极为罕见的胸腺肿瘤,迄今为止报道的病例很少。本病例报告一例45岁男性罕见胸腺瘤。CT增强示纵隔血管前腔室一大块肿块,以脂肪衰减为主,浸润纵隔内脏腔室两侧,向上延伸至双侧心膈角及肋膈前角,向右心室前方延伸,伴心包脂肪面消失,右侧气管旁及AP窗少量亚厘米淋巴结,右侧肺门淋巴结钙化。提示高分化脂肪肉瘤/胸腺肉瘤。CT引导下的原位组织活检未见明确结果,再次活检显示纤维胶原组织伴坏死区域,背景灶性黏液样改变,存在梭形至卵圆形细胞,核轻度多形性,S100、细胞角蛋白、CD34、desmin阴性。在没有体外循环(CPB)的支持下,在心包完整的情况下进行了细致的解剖,切除了整个肿瘤。手术活检标本的最终组织病理学报告与局灶神经节细胞分化的去分化胸腺肉瘤一致。术后随访胸部CECT未见血管前腔室残余肿块。患者术后接受30 Gy放射治疗(PORT),术后6个月无病无症状,放疗科常规随访。
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引用次数: 0
Role of the Seasonal Cycle in Atrial Fibrillation Seen after Coronary Artery Bypass Surgery 季节周期在冠状动脉搭桥术后房颤中的作用
Pub Date : 2020-06-15 DOI: 10.4236/wjcs.2020.106012
E. Çelik, A. Çora, Kadir Burhan Karadem, Dinçer Uysal
Background: We aimed to investigate the effect of seasons on atrial fibrillation that occurred after coronary bypass surgery operation. Method: 187 patients underwent coronary artery bypass operation in our clinic between July 2018 - July 2019. Isolated coronary artery bypass graft operation was performed with cardiopulmonary bypass to179 of these patients. Forty three patients that developed atrial fibrillation after coronary bypass operation, demographic, laboratory findings and date of atrial fibrillation data investigated retrospectively. Results: Forty three patients developed atrial fibrillation after coronary artery bypass surgery. Forty one patients operated in winter, 48 in spring, 47 in summer, 43 in autumn and 13 patients developed atrial fibrillation in winter, 11 (25.6%) in spring, 8 (20.9%) in summer and 11 (23.3%) in autumn respectively. There is no statistical significance found by Z test that performed for all seasons for atrial fibrillation. Conclusion: There are many reasons that could play role on developing atrial fibrillation after coronary artery bypass surgery. There are many publications that report vitamin D deficiency as a reason for developing atrial fibrillation after coronary bypass surgery. In our study, we did not evaluate a relationship between the development of post operative atrial fibrillation and seasons.
背景:我们旨在探讨季节对冠状动脉搭桥术后房颤的影响。方法:2018年7月至2019年7月在我院行冠状动脉搭桥术的患者187例。其中179例患者行离体冠状动脉旁路移植术并体外循环。对43例冠状动脉搭桥术后发生房颤的患者进行回顾性调查,统计资料、实验室检查结果和房颤发生日期。结果:43例患者在冠状动脉搭桥术后发生房颤。冬季手术41例,春季48例,夏季47例,秋季43例;冬季发生房颤13例,春季11例(25.6%),夏季8例(20.9%),秋季11例(23.3%)。所有季节房颤的Z检验均无统计学意义。结论:冠状动脉搭桥术后发生心房颤动的原因多种多样。有许多出版物报道维生素D缺乏是冠状动脉搭桥手术后发生房颤的原因。在我们的研究中,我们没有评估术后房颤的发展与季节之间的关系。
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引用次数: 0
Congenital Cyanogenic Heart Disease in Children: About 420 Cases in Africa 儿童先天性青紫性心脏病:非洲约420例
Pub Date : 2020-06-15 DOI: 10.4236/wjcs.2020.106011
A. Fall, A. Sow, I. Basse, A. M. Coundoul, Fondjo P. S. Monoue, A. Thiongane, D. Boiro, I. Ly, B. Niang, I. Ba, G. Diagne, P. Faye, O. Ndiaye
Congenital cyanogenic heart disease (CCHD) is a malformation of the heart and large vessels characterized by an oxygen desaturation in the arterial blood, responsible for cyanosis. The general objective was to study the profile of CCHD in Senegalese hospitals. This is a retrospective study carried out over a period of 8 years (January 1, 2010 - December 31, 2017) and including all children aged 0 to 16 years followed for a CCHD. The hospital prevalence was 0.87% for 420 cases collected. The sex ratio was 1.44 and the average age at diagnosis was 16 months. First degree parental consanguinity was noted in 36 cases (30.78%). The main reasons for consultation were breathing difficulty in 242 cases (57.62%) and fever in 136 patients (32.36%). Apart from cyanosis, the clinical signs were dominated by the heart murmur in 313 cases (74.7%), tachycardia in 283 cases (67.38%) and digital hippocratism in 162 cases (38.57%). Cardiomegaly was found in 239 patients (83.36%). The main types of CCHD were tetralogy of Fallot and transposition of the large vessels. In biology, 206 patients (49.05%) presented polyglobulia. A complete surgical cure was carried out in 22 patients (5.24%). Complications were anoxic crisis (52 cases) and hemorrhagic syndrome (17 cases). There were 97 deaths (28.28%) during hospitalization. The diagnosis of CCHD is late in our country and surgical management is poor explaining the high mortality.
先天性青紫性心脏病(CCHD)是一种心脏和大血管的畸形,其特征是动脉血中的氧饱和度过低,导致青紫。总的目标是研究塞内加尔医院中慢性冠心病的概况。这是一项为期8年(2010年1月1日至2017年12月31日)的回顾性研究,包括所有0至16岁的CCHD儿童。420例患者住院患病率为0.87%。性别比为1.44,诊断时平均年龄为16个月。一级亲缘关系36例(30.78%)。就诊原因主要为呼吸困难242例(57.62%),发热136例(32.36%)。除发绀外,临床体征以心脏杂音为主313例(74.7%),心动过速283例(67.38%),数字化希波底162例(38.57%)。239例(83.36%)患者出现心脏肿大。冠心病的主要类型为法洛四联症和大血管转位。生物学方面,206例(49.05%)出现多球性贫血。手术完全治愈22例(5.24%)。并发症为缺氧危象52例,出血性综合征17例。住院期间死亡97例(28.28%)。CCHD在我国诊断较晚,手术治疗较差,故死亡率高。
{"title":"Congenital Cyanogenic Heart Disease in Children: About 420 Cases in Africa","authors":"A. Fall, A. Sow, I. Basse, A. M. Coundoul, Fondjo P. S. Monoue, A. Thiongane, D. Boiro, I. Ly, B. Niang, I. Ba, G. Diagne, P. Faye, O. Ndiaye","doi":"10.4236/wjcs.2020.106011","DOIUrl":"https://doi.org/10.4236/wjcs.2020.106011","url":null,"abstract":"Congenital cyanogenic heart disease (CCHD) is a malformation of the heart \u0000and large vessels characterized by an oxygen desaturation in the arterial \u0000blood, responsible for cyanosis. The general objective was to study the profile \u0000of CCHD in Senegalese hospitals. This is a retrospective study carried out over \u0000a period of 8 years (January 1, 2010 - December 31, 2017) and including all children \u0000aged 0 to 16 years followed for a CCHD. The hospital prevalence was 0.87% for \u0000420 cases collected. The sex ratio was 1.44 and the average age at diagnosis \u0000was 16 months. First degree parental consanguinity was noted in 36 cases (30.78%). The main reasons for \u0000consultation were breathing difficulty in 242 cases (57.62%) and fever \u0000in 136 patients (32.36%). Apart from cyanosis, the clinical signs were \u0000dominated by the heart murmur in 313 cases (74.7%), tachycardia in 283 cases \u0000(67.38%) and digital hippocratism in 162 cases (38.57%). Cardiomegaly was found \u0000in 239 patients (83.36%). The main types of CCHD were tetralogy of Fallot and \u0000transposition of the large vessels. In biology, 206 patients (49.05%) presented \u0000polyglobulia. A complete surgical cure was carried out in 22 patients (5.24%). \u0000Complications were anoxic crisis (52 cases) and hemorrhagic syndrome (17 \u0000cases). There were 97 deaths (28.28%) during hospitalization. The diagnosis of \u0000CCHD is late in our country and surgical management is poor explaining the high \u0000mortality.","PeriodicalId":23646,"journal":{"name":"World Journal of Cardiovascular Surgery","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84457470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of 100 Cases of Mortality after Cardiac Surgery: A Single-Center Experience in Bangladesh     100例心脏手术后死亡率评估:孟加拉国单中心经验
Pub Date : 2020-05-18 DOI: 10.22541/au.158981360.05697032
Dharmendra Joshi, M. Acharya, Niraj Bhattarai, Md. Abir Tazim Chowdhury, M. Alauddin, Md. Rezwanul Hoque
AbstractBackground: Vigilance ensures safety in cardiac surgery. Performance in cardiac surgery is often measured by short-term mortality. Several risk factors like advanced age, female gender, higher body mass index, decreased left ventricular function, emergent, and redo operations have appeared recurrently as poor prognostic variables. Evaluation of postoperative mortality is crucial to find loopholes to provide proper care and reduce preventable mortality after cardiac surgery in developing countries with limited infrastructures and resources.Methods: This is a retrospective study conducted in the Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University. Perioperative data of 100 cases of mortality after cardiac surgery performed from 1 January 2014 to 30 May 2018 were collected from the university medical record. The data on age, gender, body mass index, preoperative investigations, diagnoses, types of operations, details of cardiopulmonary bypass, and postoperative period of the study populations were evaluated.Results: During the study period, about 1627 cases of cardiac surgery were done with an overall mortality rate of 6.15%. The mean age was 41.05 ± 20.19 (0 - 68) years, and 66% of patients were male. Preoperative ejection fraction (EF) of the study population was an average 56.63% ± 11.85%; 9% of the patients had EF < 40%. Off-pump coronary artery bypass (32.27%) was the most commonly performed surgery followed by mitral valve replacement (24.28%). On-pump cardiac surgery was done among 65% of the study population with a mean cross-clamp time and bypass time of 32.56 ± 11.55 minutes and 80.57 ± 18.09 minutes, respectively. Most of the mortality was found in the first two weeks after surgery.Conclusion: Mortality after cardiac surgery is multifactorial. A large-scale prospective study with comparative groups is required to find out preventable measures of mortality after cardiac surgery which will improve the quality of services provided to the patients in developing countries.Keywords:Cardiac Surgery, Morbidity, Mortality, Evaluation
摘要背景:保持警惕,确保心脏手术安全。心脏手术的表现通常以短期死亡率来衡量。高龄、女性、较高的身体质量指数、左心室功能下降、紧急手术和重做手术等危险因素作为不良预后变量反复出现。在基础设施和资源有限的发展中国家,评估术后死亡率对于发现漏洞以提供适当护理和减少心脏手术后可预防的死亡率至关重要。方法:本研究是在Bangabandhu Sheikh Mujib医科大学心脏外科进行的回顾性研究。从大学病历中收集了2014年1月1日至2018年5月30日100例心脏手术后死亡病例的围手术期数据。评估研究人群的年龄、性别、体重指数、术前调查、诊断、手术类型、体外循环细节和术后时间等数据。结果:研究期间共完成心脏手术1627例,总死亡率6.15%。平均年龄41.05±20.19(0 ~ 68)岁,男性占66%。研究人群术前射血分数(EF)平均为56.63%±11.85%;9%的患者EF < 40%。非体外循环冠状动脉搭桥术(32.27%)是最常见的手术,其次是二尖瓣置换术(24.28%)。65%的研究人群进行了无泵心脏手术,平均交叉钳夹时间和旁路时间分别为32.56±11.55分钟和80.57±18.09分钟。大多数死亡发生在手术后的头两周。结论:心脏手术后死亡率是多因素的。需要对比较组进行大规模前瞻性研究,以找出心脏手术后死亡率的可预防措施,从而提高向发展中国家患者提供的服务质量。关键词:心脏外科,发病率,死亡率,评价
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引用次数: 0
Indications and Results of Repair of the Rhumatismal Valve in Children in Senegal concerning 63 Cases 塞内加尔儿童人工瓣膜修复63例的适应证及效果分析
Pub Date : 2020-05-11 DOI: 10.4236/wjcs.2020.105007
M. Diop, Papa Amath Diagne, N. F. Sow, P. S. Ba, M. Gaye, P. O. Ba, S. Diatta, M. S. Diop, Marème Soda Mbaye, P. A. Dieng, A. G. Ciss, A. Ndiaye
In Africa, acute rheumatic fever is endemic. Cardiac involvement is one of the most common complications in the form of valvular heart disease representing all damages to the heart valves. It is in this perspective that we realized this study whose general objective was to evaluate the results of mitral repair surgery in children in Senegal and the specific objective was to state the indications for mitral repair surgery and assess the results in terms of morbidity and mortality. This is a retrospective and analytical monocentric study, in the thoracic and cardiovascular surgery department of FANN National University Hospital Center in Dakar. It took place over a period of 30 months. All the patients who underwent mitral surgery, aged less than 18 years were included. The total number of patients was 63, including 39 girls and 24 boys, a sex ratio of 0.62. The average age at the time of the surgery was 12 years old [5 - 17]. The functional symptomatology was dominated by the dyspnea found in all the patients. Cardiac ultrasound was diagnosed with mitral regurgitation in all patients. For all surgical procedures, the approach was a vertical midline sternotomy. The mitral valve was approached by left atriotomy in 40 patients (63.5%) and by transseptal way in 23 patients. All patients had undergone mitral valve repair associated or not with either aortic valve repair in 9 patients (14.2%), aortic valve replacement in 3 patients (4.8%), or one tricuspid valve repair in 31 patients (49%). The average duration of intubation was 6 hours [2 - 52]. The average length of stay in intensive care was 2 days. Postoperative complications have been observed. Surgery was performed in 10 patients with 3 mitral valve replacements, 2 aortic valve replacements, a double mitral and an aortic valve replacement associated with a tricuspid repair and in 4 cases a perfection of their mitral repair. Early and late surgical mortality was zero. The average follow-up time for our patients was 9 months [1 - 26]. During their follow-up, the evolution was favorable in 89% of patients who no longer had any functional symptoms.
在非洲,急性风湿热是地方病。心脏受累是瓣膜性心脏病最常见的并发症之一,它代表了心脏瓣膜的所有损害。正是从这个角度出发,我们意识到本研究的总体目标是评估塞内加尔儿童二尖瓣修复手术的结果,具体目标是说明二尖瓣修复手术的适应症,并从发病率和死亡率方面评估结果。这是一项回顾性和单中心分析研究,在达喀尔FANN国立大学医院中心胸外科和心血管外科进行。整个过程持续了30个月。所有接受二尖瓣手术的患者,年龄小于18岁。患者总数63例,其中女生39例,男生24例,性别比0.62。手术时的平均年龄为12岁[5 - 17]。所有患者的功能症状以呼吸困难为主。所有患者心脏超声均诊断为二尖瓣返流。所有手术入路均为垂直中线胸骨切开术。40例(63.5%)经左心房切开入路二尖瓣,23例经隔膜入路二尖瓣。所有患者均行二尖瓣修复术,其中9例(14.2%)伴有主动脉瓣修复术,3例(4.8%)伴有主动脉瓣置换术,31例(49%)伴有三尖瓣修复术。平均插管时间为6小时[2 - 52]。重症监护的平均住院时间为2天。观察到术后并发症。10例患者进行手术,3例二尖瓣置换术,2例主动脉瓣置换术,1例双二尖瓣置换术,1例主动脉瓣置换术伴三尖瓣修复,4例二尖瓣修复完全。手术早期和晚期死亡率均为零。患者平均随访时间为9个月[1 - 26]。在随访期间,89%不再有任何功能性症状的患者的进化是有利的。
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引用次数: 0
Analysis of Patients with LifeVest after Cardiac Surgery 心脏手术后患者生命周期分析
Pub Date : 2020-05-11 DOI: 10.4236/wjcs.2020.105008
V. Hajiyev, T. Erkenov, A. Smechowski, S. Just, O. Grimmig, D. Fritzsche
Background: Patients with left ventricular ejection fraction (LVEF) ≤ 35% are at a high risk of sudden cardiac death (SCD) and benefit from implantable cardioverter-defibrillator (ICD) therapy. ICD implantation is not indicated during the first 40 days after acute myocardial infarction and Methods: This is a retrospective study conducted in the Heart Center in Cottbus. From 02.2015 through 02.2018 26 WCD patients were retrospectively analyzed and followed-up. Patient demographics, defibrillation treatments, and daily wear times were retrospectively obtained from our clinical database and LifeVest network. The patients were questioned about actual NYHA grade and implanted ICD at the end of follow-up. Results: Twenty-five patients (mean age 65, 22 men, 3 women) were treated with a WCD in response to heart failure (mean EF = 24%) after cardiac surgery (21 CABG, 1 AVR, 1 AVR + CABG, 1 AVR + MVR, MVR + CABG). Average daily use of a WCD was 22.1 (SD ± 2.7) hours which were worn for 85 days (SD ± 35). At that time 11.96 (SD ± 15) events were detected but not treated, 1 defibrillation performed and no asystole seen. At the end of follow-up (12 months, SD ± 9) 20 patients were questioned. All of the patients were alive and 5 (25%) of them were with implanted ICD. 10 (50%) patients were in NYHA grade I, 3 (12%) in NYHA grade II, 3 (12%) between grade II-III, 2 (8%) in grade III and 2 (8%) patients in NYHA grade IV. Conclusions: A WCD is an effective therapy for prevention of sudden cardiac death during the recovery period of heart function after cardiac surgery. This is treatment with high patient compliance.
背景:左心室射血分数(LVEF)≤35%的患者是心源性猝死(SCD)的高危人群,可从植入式心律转复除颤器(ICD)治疗中获益。急性心肌梗死后的头40天内不需要植入ICD。方法:这是一项在Cottbus心脏中心进行的回顾性研究。对2015年2月至2018年2月26例WCD患者进行回顾性分析和随访。从我们的临床数据库和LifeVest网络中回顾性获得患者人口统计资料、除颤治疗和每日佩戴次数。随访结束时询问患者实际NYHA分级和植入ICD。结果:25例患者(平均年龄65岁,22例男性,3例女性)在心脏手术(21例CABG, 1例AVR, 1例AVR + CABG, 1例AVR + MVR, MVR + CABG)后因心力衰竭(平均EF = 24%)而接受WCD治疗。WCD平均每天使用22.1 (SD±2.7)小时,使用85天(SD±35)。当时检测到11.96 (SD±15)例事件,但未进行治疗,1例进行除颤,未见心脏骤停。随访结束时(12个月,SD±9)对20例患者进行问询。所有患者均存活,其中5例(25%)植入ICD。NYHA I级10例(50%),NYHA II级3例(12%),II-III级3例(12%),III级2例(8%),IV级2例(8%)。结论:A WCD是预防心脏手术后心功能恢复期心源性猝死的有效治疗方法。这种治疗具有很高的患者依从性。
{"title":"Analysis of Patients with LifeVest after Cardiac Surgery","authors":"V. Hajiyev, T. Erkenov, A. Smechowski, S. Just, O. Grimmig, D. Fritzsche","doi":"10.4236/wjcs.2020.105008","DOIUrl":"https://doi.org/10.4236/wjcs.2020.105008","url":null,"abstract":"Background: Patients with left ventricular ejection fraction (LVEF) ≤ 35% are \u0000at a high risk of sudden cardiac death (SCD) and benefit from implantable \u0000cardioverter-defibrillator (ICD) therapy. ICD implantation is not indicated \u0000during the first 40 days after acute myocardial infarction and Methods: This is a retrospective \u0000study conducted in the Heart Center in Cottbus. From 02.2015 through 02.2018 26 \u0000WCD patients were retrospectively analyzed and followed-up. Patient demographics, \u0000defibrillation treatments, and daily wear times were retrospectively obtained \u0000from our clinical database and LifeVest network. The patients were questioned \u0000about actual NYHA grade and implanted ICD at the end of follow-up. Results: Twenty-five \u0000patients (mean age 65, 22 men, 3 women) were treated with a WCD in response to \u0000heart failure (mean EF = 24%) after cardiac surgery (21 CABG, 1 AVR, 1 AVR + \u0000CABG, 1 AVR + MVR, MVR + CABG). Average daily use of a WCD was 22.1 (SD ± 2.7) hours \u0000which were worn for 85 days (SD ± 35). At that time 11.96 (SD ± 15) events were \u0000detected but not treated, 1 defibrillation performed and no asystole seen. At \u0000the end of follow-up (12 months, SD ± 9) 20 patients were questioned. All of \u0000the patients were alive and 5 (25%) of them were with implanted ICD. 10 (50%) \u0000patients were in NYHA grade I, 3 (12%) in NYHA grade II, 3 (12%) \u0000between grade II-III, 2 (8%) in grade III and 2 (8%) patients in NYHA grade IV. Conclusions: A WCD is an effective therapy for prevention of sudden \u0000cardiac death during the recovery period of heart function after cardiac \u0000surgery. This is treatment with high patient compliance.","PeriodicalId":23646,"journal":{"name":"World Journal of Cardiovascular Surgery","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82566089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inotropic Requirement in Patients Undergoing Coronary Artery Bypass Grafting (CABG) in RSUP Dr. Hasan Sadikin Bandung in 2014-2016 2014-2016年RSUP患者接受冠状动脉旁路移植术(CABG)的肌力需求
Pub Date : 2020-04-10 DOI: 10.4236/wjcs.2020.104006
R. W. Sudjud, A. Catriona, R. Kadarsah
Inotropic agents are indicated to treat ventricular dysfunction that frequently found post-CABG surgery. However, the use of inotropic isn’t free from disadvantageous side effects and is related to higher morbidity and mortality in post-CABG surgery patients. Several risk factors are known to affect higher need for inotropic agents’ post-CABG surgery. This study aims to discover the inotropic requirement in patients undergoing CABG surgery based on age, sex, preoperative left ventricular ejection fraction (LVEF), comorbidities, cross clamping time (CCT), and cardiopulmonary bypass (CPB) duration in Hasan Sadikin General Hospital Bandung in 2014-2016. This study is a descriptive cross-sectional study done retrospectively through medical records. This study found the inotropic requirement post-CABG surgery was 130 patients (74.3%). The inotropic requirement based on age was 28 patients (80.0%) > 65 years old, 112 patients (75.7%) were male, 18 patients (66.7%) were female, 19 patients (100%) with  LVEF, 41 patients (85.4%) with DM, 20 patients (90.9%) with CKD, 44 patients (93.6%) with >90 minute CCT, 37 patients (90.2%) with >120 minute duration CPB. In conclusion, there was a higher inotropic requirement in patients with age > 65 years old, preoperative LVEF  comorbidities, CPB duration > 120 minutes and CCT > 90 minutes.
肌力药物用于治疗cabg术后常见的心室功能障碍。然而,肌力的使用并非没有不利的副作用,并且与cabg术后患者较高的发病率和死亡率有关。已知有几个危险因素会影响冠脉搭桥术后肌力药物的高需求。本研究旨在了解2014-2016年万隆哈桑萨迪金总医院CABG患者在年龄、性别、术前左室射血分数(LVEF)、合并症、交叉夹持时间(CCT)和体外循环(CPB)持续时间等方面的肌力需求。本研究是一项回顾性的描述性横断面研究。本研究发现,cabg术后肌力需求为130例(74.3%)。基于年龄的肌力需求为> 65岁28例(80.0%),男性112例(75.7%),女性18例(66.7%),LVEF 19例(100%),DM 41例(85.4%),CKD 20例(90.9%),CCT >90分钟44例(93.6%),CPB >120分钟37例(90.2%)。综上所述,年龄> 65岁、术前LVEF合并症、CPB持续时间> 120分钟、CCT > 90分钟的患者有更高的肌力需求。
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引用次数: 0
Lifesaving Emergency Sternotomy in Traumatic Cardiac Tamponade in a Teaching Hospital in Ghana: Survival of Two Rare Cases 加纳一家教学医院急诊胸骨切开术治疗外伤性心包填塞:两例罕见病例的存活
Pub Date : 2020-03-26 DOI: 10.4236/wjcs.2020.103005
I. Okyere, S. G. Brenu, P. Okyere
Introduction: Patients presenting with cardiac injuries from gunshot wounds and blunt chest trauma have high mortality, without any observed survival benefit when presenting with cardiac tamponade. Cardiac tamponade is a life-threatening hemodynamically significant compression of the heart by a sudden or gradual accumulation of collections in the pericardial space that incites and overrides the body’s compensatory mechanism. Clinical Case: We present and discuss the successful management and survival of two patients with traumatic cardiac tamponade from gunshot wounds to the precordium who underwent successful lifesaving median sternotomy at a Teaching Hospital in Ghana with a new Cardiovascular and Thoracic Surgery Unit. Discussion: Usually the diagnosis of cardiac tamponade from traumatic haemopericardium is made by clinical findings which though may not always be present especially after blunt chest trauma. EFAST is a reliable tool for diagnosing and following cardiac tamponade. Median sternotomy is the standard procedure in these patients to access and repair cardiac injury either with or without cardiopulmonary bypass. Conclusion: Emergency median sternotomy in patients with cardiac tamponade from chest trauma especially after EFAST diagnosis can be lifesaving even in less resourced centres.
以枪伤和钝性胸部创伤为心脏损伤的患者死亡率很高,当出现心脏填塞时,没有任何观察到的生存益处。心包填塞是一种危及心脏血流动力学的严重压迫,由心包间隙突然或逐渐积聚的积液引起,可刺激并破坏机体的代偿机制。临床病例:我们介绍并讨论了两例枪伤致心前膜创伤性心包填塞患者的成功治疗和生存,他们在加纳的一家教学医院接受了救命的胸骨正中切开术,该医院有一个新的心血管和胸外科部门。讨论:外伤性心包积血的诊断通常是通过临床表现来确定的,尽管临床表现并不总是存在,特别是在钝性胸部创伤后。EFAST是诊断和跟踪心脏填塞的可靠工具。胸骨正中切开术是这些患者接受和修复心脏损伤的标准手术,无论是否有体外循环。结论:急诊胸骨正中切开术治疗胸外伤引起的心包填塞,特别是在快速诊断后,即使在资源不足的中心也能挽救生命。
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引用次数: 0
期刊
World Journal of Cardiovascular Surgery
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