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Standards have been compiled on the basis of the clinical picture of the disease as well as objective, laboratory, instrumental-apparatus data. The dynamics of the patient's health were evaluated using concrete indices--normalization or reduction by 10-30% of the initial systolic pressure, absence of painful sensations, increase of range of articular movements, normalization of body temperature, blood indices, urine and oth. Treatment quality values were determined by comparison of results to the preplanned and are evaluated by a three-point rate--good, fair, poor.

The authors examined clinically and immunologically 60 patients with multiple sclerosis. One group (30 patients) received prednisolone in the complex treatment while the second group (30 patients) received only complex treatment. A control group of 20 healthy persons was examined. Patients of the first group showed marked neurological and immunological disorders which is considered as a complication due to the empiric prednisolone doses.

The state of lipid peroxidation and activity of dehydrogenases, transaminases and creatinphosphokinase was studied in rats and 94 patients with mild and average--severe head injuries. A relationship has been found between activation of peroxidation and reduction of activity of enzymes participating in energy reactions that along with activation of transamination evidences reduction of the energy charge of the body. Activation of peroxidation plays a major role in the development of posttraumatic brain edema and especially after mild head injury.

The authors analyzed the condition of 51 patients in the early period of operation for ulcer and cholelithiasis. It was found that most patients showed asthenic, dyspeptic and pam syndromes, anemia, hypoacidic or achylous gastritis, inflammation at the operative site. As a result of treatment at the Mirgorod health resort (physiotherapy, mineral water) there occurred a significant improvement in the patients' condition. It is concluded that rehabilitation of patients following surgical intervention on the 20th day of operation for ulcer and cholelithiasis at the Mirgorod health resort has good perspectives.

Four patients with acute intermittent porphyria (AIP) were treated and followed-up. It was established that in AIP urinary pigments have specific absorption spectra in the visible light range. Clinical manifestation and the severity of the disease course correlated with the amount of excretion of copro- and uroporphyrin and their characteristic spectrum of light absorption. It is concluded that of significance in the AIP pathogenesis is the level of formation of copro- and uroporphyrin isomers which may directly effect the nervous tissue and clinical manifestations of AIP. It is recommended to use plasmapheresis in biohemosorption by means of extracorporeal donor spleen.

A comparative morphological study of the liver in acute blood loss and massive thromboembolism of the pulmonary artery was carried on basis of early autopsies. Histoenzymatic and correlation analysis was used to study the characteristic features of the metabolism of hepatocytes in conditions of acute blood loss and massive pulmonary artery thromboembolism.

In the treatment of patients with different forms of dysbacteriosis routine bacterial preparations (coli-, lacto-, bifidumbacterin) were supplemented by sporeforming aerobic Bacillus bacteria. It was found that efficacy of treatment in patients receiving sporeforming bacteria was 20-30% higher than traditional bacterial agents.