Vrachebnoe delo最新文献

Dynamic hepato-bilio-scintigraphy was performed in 43 patients with diabetes mellitus. An analysis of results showed that characteristic of patients with diabetes mellitus is a reduction of the detoxicating and bile excretory function of the liver which was most pronounced in patients with insulin-dependent type in the condition of secondary sulfanylamide resistance. Typical of diabetes mellitus disorder of the gallbladder function was its hypotonia and dyskinesia.

Results are reported of thermographic examination of 51 patients with acute respiratory viral infections. It was established that the patients showed an increase of the radiation temperature of the skin of the nose, floor of the auricle, in the projection of the sternocleidomastoid muscles and increased submaxillary lymphatic nodes independent of the etiological factor and disease severity grade. Hyperthermia of the nose on thermograms was more frequently observed in patients with rhinitis. Informative were differences in the temperatures between the external auditory meatus and the lobule of the ear which decrease in the acute period of the disease in accordance with its severity. In most convalescents normalization of the thermal picture of the face coincides by terms with clinical convalescence while hyperthermia of the neck is maintained for a longer time.

The state of the kallikrein-kinin system of the blood (KKS): kallikrein (KK), prekallikrein (PK), general arginine-esterase activity (GAEA), alpha 1 inhibitor of protease (IP) and alpha 2-macroglobulin (MG). The initial period of the disease was characterized by an increase of the level of KK, GAEA, IP and MG and a reduction of PK. It was established that the maximal activation of KKS develops in patients with the erythematous form of erysipelas during the first days of the disease, with the hemorrhagic form--on the 2 week. During convalescence KKS indices showed the reverse dynamics but did not reach normal levels in most patients. It is suggested that there is a relationship of the "rapid" form of KKS activation with formation of erythematous erysipelas, the "slow"--with hemorrhagic erysipelas. It is recommended to use the KKS indices, primarily KK activity for prediction of hemorrhagic erysipelas at the early prehemorrhagic stage.

The authors studied the blood-brain barrier permeability in 70 patients depending on the severity and terms of bacterial meningoencephalitis. It was shown that employment of the probability-statistical analysis of quantitative content of metal in the blood and cerebrospinal fluid allows to evaluate the working regimen of the blood-brain barrier from initial manifestations of functional insufficiency to failure of barrier compensation systems.

A clinical and immunological study is presented of 1030 practically healthy persons inhabiting Kiev from the moment of the Chernobyl accident. It was established clinically that during the last 5 years more frequent became acute respiratory viral infections, exacerbation of existing infection foci, appearance of complaints of reduced working capacity, somnolence apathy, increased fatiguability, worsening of memory, periodic subfebrility and oth. This symptom complex was determined as the "increased fatiguability syndrome". It was characterized immunologically by different changes showing most frequently a reduction of the functional activity of natural killers. The authors analyze different variants of immunological disorders in this group of subjects and give practical recommendations on using immunotropic drugs. They emphasize the importance of a service of clinical immunology in Ukraine able to organize special services to the population.

A comparative analysis is presented of the effect of sonic waves and drug treatment of 31 patients with postvagotomy gastrostasis. The motor gastric activity was evaluated by clinical data and electrogastrography. It was established that the effect of sonic waves (frequency: 2.5 kHz, sound stream intensity 0.66 Wt/cm2 2 times daily per 10-15 min. for 3-10 days) favour rapid restoration of the motor activity of stomach and intestines and are a favourable background for the reduced probability of development of pulmonary and cardio-vascular complications that facilitates the postoperative period in this category of patients.

Results are reported of an immunological examination of 534 patients with digestive diseases and 130 healthy persons. 282 patients subjected to radiation effects showed a marked and persistent T-lymphocytopenia, B-lymphocytosis, reduction of the content of T-helpers, T-suppressors, dysimmunoglobulinemia characterized by reduction of IgG content and excessive IgA secretion. These changes were observed during the period of exacerbation and remission requiring the use of immunocorrective agents.