Siobhan Elizabeth Fitzpatrick, Tamara Crittenden, David I Watson, Nicola R Dean
Introduction: Rectus diastasis of parity is the separation of the abdominal muscles that can occur after childbearing. We hypothesized that a subpopulation of women with rectus diastasis also present with back pain and/or urinary incontinence, a condition referred to as symptomatic established rectus diastasis, and this results in impaired health-related quality of life. This study identified the prevalence of symptomatic established rectus diastasis in primiparous women and measured their health-related quality of life.
Methods: Gravid nulliparous women over 18 years old were consecutively recruited from December 2021 to August 2022 and followed prospectively. Inter-rectus distances were measured with ultrasound in early pregnancy, and 6-week, 6-month, and 12-month postpartum. Patient reported outcome measures included the Oswestry Disability Index (ODI) for back pain, International Consultation on Incontinence Questionnaires Urinary Incontinence Short Form (ICIQ-UI SF) for urinary incontinence, and the 36-item short form (SF-36) for health-related quality of life.
Results: Two-hundred and thirteen women were recruited, of which 192 underwent ultrasound measurement in early pregnancy, 130 at 6-week postpartum, 120 at 6-month, and 109 at 12-month. There was a significant increase in mean inter-rectus distance over the study period (p < 0.001). The proportion of women with rectus diastasis at 12-month postpartum (> 30 mm) was 30.3% and compared to those without they had worse back pain (p = 0.014) but no difference in urinary incontinence (p > 0.05). Women with symptomatic established rectus diastasis at 12-month postpartum (rectus diastasis and back pain (ODI > 0)), made up 25% of the cohort and had significantly worse health-related quality of life than those without (p < 0.05). Predictive factors for symptomatic established rectus diastasis included increased total fetal birthweight (OR 3), lower maternal BMI (OR 1.2), and gestational diabetes (OR 6.7).
Conclusion: This study of gravid nulliparous women from early pregnancy until 12-month postpartum identified rectus diastasis in 30.3% and symptomatic established rectus diastasis in 25%. Women with symptomatic established rectus diastasis had significantly worse health-related quality of life.
{"title":"Prevalence of Symptomatic Established Rectus Diastasis of Parity in Primiparous Women: A Prospective Cohort Study From Early Pregnancy to 1-Year Postpartum.","authors":"Siobhan Elizabeth Fitzpatrick, Tamara Crittenden, David I Watson, Nicola R Dean","doi":"10.1002/wjs.70227","DOIUrl":"https://doi.org/10.1002/wjs.70227","url":null,"abstract":"<p><strong>Introduction: </strong>Rectus diastasis of parity is the separation of the abdominal muscles that can occur after childbearing. We hypothesized that a subpopulation of women with rectus diastasis also present with back pain and/or urinary incontinence, a condition referred to as symptomatic established rectus diastasis, and this results in impaired health-related quality of life. This study identified the prevalence of symptomatic established rectus diastasis in primiparous women and measured their health-related quality of life.</p><p><strong>Methods: </strong>Gravid nulliparous women over 18 years old were consecutively recruited from December 2021 to August 2022 and followed prospectively. Inter-rectus distances were measured with ultrasound in early pregnancy, and 6-week, 6-month, and 12-month postpartum. Patient reported outcome measures included the Oswestry Disability Index (ODI) for back pain, International Consultation on Incontinence Questionnaires Urinary Incontinence Short Form (ICIQ-UI SF) for urinary incontinence, and the 36-item short form (SF-36) for health-related quality of life.</p><p><strong>Results: </strong>Two-hundred and thirteen women were recruited, of which 192 underwent ultrasound measurement in early pregnancy, 130 at 6-week postpartum, 120 at 6-month, and 109 at 12-month. There was a significant increase in mean inter-rectus distance over the study period (p < 0.001). The proportion of women with rectus diastasis at 12-month postpartum (> 30 mm) was 30.3% and compared to those without they had worse back pain (p = 0.014) but no difference in urinary incontinence (p > 0.05). Women with symptomatic established rectus diastasis at 12-month postpartum (rectus diastasis and back pain (ODI > 0)), made up 25% of the cohort and had significantly worse health-related quality of life than those without (p < 0.05). Predictive factors for symptomatic established rectus diastasis included increased total fetal birthweight (OR 3), lower maternal BMI (OR 1.2), and gestational diabetes (OR 6.7).</p><p><strong>Conclusion: </strong>This study of gravid nulliparous women from early pregnancy until 12-month postpartum identified rectus diastasis in 30.3% and symptomatic established rectus diastasis in 25%. Women with symptomatic established rectus diastasis had significantly worse health-related quality of life.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tan Jun Guang Kendric, Sharie Ann Apikotoa, Zi Qin Ng, Ruwan Wijesuriya
Background: ROME IV diagnostic criteria describe functional gallbladder disorder as biliary pain in the absence of gallstones, supported by a low ejection fraction on gallbladder scintigraphy. However, clinicians have noticed histopathological analysis of gallbladders to intermittently reveal cholelithiasis. Our study aims to quantify this and to reduce misdiagnosis rates of functional gallbladder disorders.
Methods: We performed a single-center retrospective cohort study at St John of God Midland Hospital in Western Australia, Perth on 484 consecutive patients undergoing hepatobiliary iminodiacetic acid (HIDA) scan between November 1, 2015 and April 1, 2024.
Results: 5.6% (27/484) of patients had functional gallbladder disorder (FGBD) diagnosed preoperatively by ROME IV underwent cholecystectomy at our center. Of this, 18.5% (5/27) were noted to have histopathological cholelithiasis despite preoperative imaging suggesting otherwise. Of the 22 patients with true gallbladder dysfunction, 70% (7/10) had resolution of symptoms after cholecystectomy, with remaining 30% (3/10) experiencing persisting symptoms and referred on for further medical workup. 5 had private follow-up and 7 did not attend follow-up appointments. Ultrasonography had a sensitivity at 64% and specificity of 88% for identifying cholelithiasis, with a negative predictive value of 81.48%.
Conclusion: Functional gallbladder disorders remain a rare but not insignificant contributor to patients with undifferentiated abdominal pain. In the setting of microlithiasis, 1 in 5 patients will have gallstones missed on preoperative imaging. These emphases the importance of considering functional aspects of biliary pain in the absence of structural pathologies and being aware of the limitations of imaging to reduce the morbidity false negatives can confer.
{"title":"Functional Gallbladder Disorders: Are We Missing Gallstones?","authors":"Tan Jun Guang Kendric, Sharie Ann Apikotoa, Zi Qin Ng, Ruwan Wijesuriya","doi":"10.1002/wjs.70230","DOIUrl":"10.1002/wjs.70230","url":null,"abstract":"<p><strong>Background: </strong>ROME IV diagnostic criteria describe functional gallbladder disorder as biliary pain in the absence of gallstones, supported by a low ejection fraction on gallbladder scintigraphy. However, clinicians have noticed histopathological analysis of gallbladders to intermittently reveal cholelithiasis. Our study aims to quantify this and to reduce misdiagnosis rates of functional gallbladder disorders.</p><p><strong>Methods: </strong>We performed a single-center retrospective cohort study at St John of God Midland Hospital in Western Australia, Perth on 484 consecutive patients undergoing hepatobiliary iminodiacetic acid (HIDA) scan between November 1, 2015 and April 1, 2024.</p><p><strong>Results: </strong>5.6% (27/484) of patients had functional gallbladder disorder (FGBD) diagnosed preoperatively by ROME IV underwent cholecystectomy at our center. Of this, 18.5% (5/27) were noted to have histopathological cholelithiasis despite preoperative imaging suggesting otherwise. Of the 22 patients with true gallbladder dysfunction, 70% (7/10) had resolution of symptoms after cholecystectomy, with remaining 30% (3/10) experiencing persisting symptoms and referred on for further medical workup. 5 had private follow-up and 7 did not attend follow-up appointments. Ultrasonography had a sensitivity at 64% and specificity of 88% for identifying cholelithiasis, with a negative predictive value of 81.48%.</p><p><strong>Conclusion: </strong>Functional gallbladder disorders remain a rare but not insignificant contributor to patients with undifferentiated abdominal pain. In the setting of microlithiasis, 1 in 5 patients will have gallstones missed on preoperative imaging. These emphases the importance of considering functional aspects of biliary pain in the absence of structural pathologies and being aware of the limitations of imaging to reduce the morbidity false negatives can confer.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Invited Commentary.","authors":"Vanessa M S Ross, Sarkis Meterissian","doi":"10.1002/wjs.70214","DOIUrl":"https://doi.org/10.1002/wjs.70214","url":null,"abstract":"","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Postoperative nutrition after pancreatoduodenectomy (PD) remains controversial. Although many centers routinely place a feeding jejunostomy tube (FJT) after PD, it is associated with morbidity. We conducted this study to compare the perioperative outcomes with and without FJT placement post-PD.
Methods: This was an open-label randomized controlled trial, in which the FJT was placed in one arm and the nasojejunal tube (NJT) in the other. All patients with periampullary neoplasm who underwent pylorus resecting PD were included in this study. The primary outcome assessed was clinically relevant delayed gastric emptying (CR-DGE), and the secondary outcomes were clinically relevant postoperative pancreatic fistula (CR-POPF), postoperative complications, and hospital stay.
Results: Forty patients were allocated to the FJT and NJT groups, and the two groups were comparable in baseline demographics, disease characteristics, and perioperative outcomes, including CR-POPF rates. The FJT group had a significantly higher CR-DGE rate (55% vs. 25%, p = 0.006), required increased use of prokinetic drugs (77.5% vs. 45%, p = 0.003), and had a longer median postoperative hospital stay (11 vs. 9 days, p = 0.007). Both groups had similar tube-related complications. In the NJT group, 22.5% of the patients with CR-DGE required parenteral nutrition. On multivariate analysis, the presence of FJT [adjusted odds ratio (aOR), 6.030 (1.431-25.402), p = 0.014] and intra-abdominal collection [aOR, 7.108 (1.026-49.224), p = 0.047] were independent risk factors for CR-DGE.
Conclusion: Post-PD placement of FJT was an independent risk factor for CR-DGE. Hence, the routine use of the FJT can be omitted after PD without compromising postoperative morbidity and nutrition.
Trial registration: The trial was registered with the Clinical Trial Register with CTRI number: CTRI/2021/02/030942 (https://ctri.nic.in/Clinicaltrials/advancesearchmain.php).
简介:胰十二指肠切除术(PD)后的营养仍然存在争议。虽然许多中心在PD后常规放置喂养空肠造瘘管(FJT),但它与发病率有关。我们进行了这项研究,以比较pd后放置FJT和不放置FJT的围手术期结果。方法:采用开放标签随机对照试验,一只手臂放置FJT,另一只手臂放置鼻空肠管(NJT)。所有接受幽门切除PD的壶腹周围肿瘤患者均被纳入本研究。评估的主要结局是临床相关的胃排空延迟(CR-DGE),次要结局是临床相关的术后胰瘘(CR-POPF)、术后并发症和住院时间。结果:40例患者被分配到FJT和NJT组,两组在基线人口统计学、疾病特征和围手术期结局(包括CR-POPF率)方面具有可比性。FJT组CR-DGE率明显较高(55%对25%,p = 0.006),需要增加促动力学药物的使用(77.5%对45%,p = 0.003),术后中位住院时间较长(11天对9天,p = 0.007)。两组都有类似的管相关并发症。在NJT组中,22.5%的CR-DGE患者需要肠外营养。多因素分析显示,FJT的存在[调整优势比(aOR), 6.030 (1.431-25.402), p = 0.014]和腹腔内收集物[aOR, 7.108 (1.026-49.224), p = 0.047]是CR-DGE的独立危险因素。结论:pd后放置FJT是发生CR-DGE的独立危险因素。因此,在不影响术后发病率和营养的情况下,PD后可以省略FJT的常规使用。试验注册:该试验已在临床试验注册中心注册,CTRI编号:CTRI/2021/02/030942 (https://ctri.nic.in/Clinicaltrials/advancesearchmain.php)。
{"title":"Pylorus Resecting Pancreatoduodenectomy With or Without Feeding Jejunostomy-A Randomized Controlled Trial.","authors":"Vaibhav Kumar Varshney, Kaushal Singh Rathore, Raghav Nayar, B Selvakumar, Subhash Soni, Peeyush Varshney, Lokesh Agarwal, Ankit Rai, Akhil Dhanesh Goel, Sabir Hussain","doi":"10.1002/wjs.70216","DOIUrl":"https://doi.org/10.1002/wjs.70216","url":null,"abstract":"<p><strong>Introduction: </strong>Postoperative nutrition after pancreatoduodenectomy (PD) remains controversial. Although many centers routinely place a feeding jejunostomy tube (FJT) after PD, it is associated with morbidity. We conducted this study to compare the perioperative outcomes with and without FJT placement post-PD.</p><p><strong>Methods: </strong>This was an open-label randomized controlled trial, in which the FJT was placed in one arm and the nasojejunal tube (NJT) in the other. All patients with periampullary neoplasm who underwent pylorus resecting PD were included in this study. The primary outcome assessed was clinically relevant delayed gastric emptying (CR-DGE), and the secondary outcomes were clinically relevant postoperative pancreatic fistula (CR-POPF), postoperative complications, and hospital stay.</p><p><strong>Results: </strong>Forty patients were allocated to the FJT and NJT groups, and the two groups were comparable in baseline demographics, disease characteristics, and perioperative outcomes, including CR-POPF rates. The FJT group had a significantly higher CR-DGE rate (55% vs. 25%, p = 0.006), required increased use of prokinetic drugs (77.5% vs. 45%, p = 0.003), and had a longer median postoperative hospital stay (11 vs. 9 days, p = 0.007). Both groups had similar tube-related complications. In the NJT group, 22.5% of the patients with CR-DGE required parenteral nutrition. On multivariate analysis, the presence of FJT [adjusted odds ratio (aOR), 6.030 (1.431-25.402), p = 0.014] and intra-abdominal collection [aOR, 7.108 (1.026-49.224), p = 0.047] were independent risk factors for CR-DGE.</p><p><strong>Conclusion: </strong>Post-PD placement of FJT was an independent risk factor for CR-DGE. Hence, the routine use of the FJT can be omitted after PD without compromising postoperative morbidity and nutrition.</p><p><strong>Trial registration: </strong>The trial was registered with the Clinical Trial Register with CTRI number: CTRI/2021/02/030942 (https://ctri.nic.in/Clinicaltrials/advancesearchmain.php).</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noa Grunberg, Nicolas Michot, David Dussard, Olivier Saint-Marc, Hugo Guillermou, Ephrem Salamé, Mehdi Ouaissi, Haythem Najah
Background: Robotic adrenalectomy (RA) is increasingly adopted, but its clinical value compared with laparoscopic adrenalectomy (LA) remains unclear. We assessed perioperative outcomes and the learning curve of RA.
Methods: A bicentric retrospective study included 228 patients who underwent adrenalectomy between 2013 and 2023 (97 RA, 131 LA). Primary outcomes were intra- and postoperative complications (Clavien-Dindo, Comprehensive Complication Index, CCI). Secondary outcomes included operative time and length of stay (LOS). Subgroup analysis evaluated tumors ≥ 6 cm. RA learning curve was assessed with cumulative sum (CUSUM) analysis.
Results: Patients in the RA group had higher ASA scores, more prior abdominal surgery, and larger tumors. Overall complication rates were similar (RA 18.6% vs. LA 17.6%, p = 0.846). RA was independently associated with shorter LOS (OR 0.48; 95% CI 0.26-0.84; p = 0.012). In tumors ≥ 6 cm, RA reduced postoperative complications (5.3% vs. 35.3%, p = 0.037). CUSUM analysis showed earlier improvements in operative time (after 25 cases) and later reductions in morbidity (after ∼ 45 cases).
Conclusions: RA is a safe alternative to LA even in complex patients. It shortens LOS overall and improves outcomes in large adrenal tumors. CUSUM analysis highlights a progressive but safe learning curve, supporting the integration of RA into endocrine surgical practice.
背景:机器人肾上腺切除术(RA)越来越多地被采用,但其与腹腔镜肾上腺切除术(LA)的临床价值尚不清楚。我们评估RA的围手术期预后和学习曲线。方法:一项双中心回顾性研究纳入了2013年至2023年间接受肾上腺切除术的228例患者(97例RA, 131例LA)。主要结局是手术内和术后并发症(Clavien-Dindo,综合并发症指数,CCI)。次要结果包括手术时间和住院时间(LOS)。亚组分析评估肿瘤≥6 cm。采用累积和(CUSUM)分析评估RA学习曲线。结果:RA组患者ASA评分较高,既往腹部手术较多,肿瘤较大。总并发症发生率相似(RA 18.6% vs LA 17.6%, p = 0.846)。RA与较短的LOS独立相关(OR 0.48; 95% CI 0.26-0.84; p = 0.012)。在≥6 cm的肿瘤中,RA减少了术后并发症(5.3% vs. 35.3%, p = 0.037)。CUSUM分析显示手术时间(25例后)较早改善,发病率较晚降低(~ 45例后)。结论:即使在复杂的患者中,RA也是LA的安全替代品。总的来说,它缩短了LOS,改善了大肾上腺肿瘤的预后。CUSUM分析强调了一个渐进但安全的学习曲线,支持将RA纳入内分泌外科实践。
{"title":"Robotic Adrenalectomy Is Associated With Shortened Hospital Stay and in Large Tumors (≥ 6 cm) May Reduce Complications.","authors":"Noa Grunberg, Nicolas Michot, David Dussard, Olivier Saint-Marc, Hugo Guillermou, Ephrem Salamé, Mehdi Ouaissi, Haythem Najah","doi":"10.1002/wjs.70221","DOIUrl":"https://doi.org/10.1002/wjs.70221","url":null,"abstract":"<p><strong>Background: </strong>Robotic adrenalectomy (RA) is increasingly adopted, but its clinical value compared with laparoscopic adrenalectomy (LA) remains unclear. We assessed perioperative outcomes and the learning curve of RA.</p><p><strong>Methods: </strong>A bicentric retrospective study included 228 patients who underwent adrenalectomy between 2013 and 2023 (97 RA, 131 LA). Primary outcomes were intra- and postoperative complications (Clavien-Dindo, Comprehensive Complication Index, CCI). Secondary outcomes included operative time and length of stay (LOS). Subgroup analysis evaluated tumors ≥ 6 cm. RA learning curve was assessed with cumulative sum (CUSUM) analysis.</p><p><strong>Results: </strong>Patients in the RA group had higher ASA scores, more prior abdominal surgery, and larger tumors. Overall complication rates were similar (RA 18.6% vs. LA 17.6%, p = 0.846). RA was independently associated with shorter LOS (OR 0.48; 95% CI 0.26-0.84; p = 0.012). In tumors ≥ 6 cm, RA reduced postoperative complications (5.3% vs. 35.3%, p = 0.037). CUSUM analysis showed earlier improvements in operative time (after 25 cases) and later reductions in morbidity (after ∼ 45 cases).</p><p><strong>Conclusions: </strong>RA is a safe alternative to LA even in complex patients. It shortens LOS overall and improves outcomes in large adrenal tumors. CUSUM analysis highlights a progressive but safe learning curve, supporting the integration of RA into endocrine surgical practice.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mélanie Loison, Matthieu Wargny, Cécile Caillard, Pascale Guillot, Maëlle Le Bras, Bertrand Cariou, Claire Blanchard, Eric Mirallié, Samuel Frey
Background: Bone mineral density (BMD) measurement at the lumbar spine, femoral neck, total hip, and distal 1/3 radius is recommended for patients with primary hyperparathyroidism (PHPT). Osteoporosis at any site justifies surgery. The distal 1/3 radius is often neglected. This study evaluated the prevalence of distal 1/3 radius measurement, the proportion of osteoporosis at this site alone, and BMD changes 1 year post-parathyroidectomy in patients with PHPT.
Methods: A total of 548 patients who underwent parathyroidectomy for PHPT between 2016 and 2024 in University Hospital Center of Nantes (France) were reviewed. Patients without pre-surgery BMD measurements at the lumbar spine or the femoral neck were excluded. BMD was assessed via dual x-ray absorptiometry before and 12-months after surgery.
Results: Four hundred patients (mean age 63.3 ± 12.3 years, 80.5% female, and 86.2% menopausal) were included. Mean baseline serum calcium was 2.76 ± 0.19 mmol/L; median PTH was 99.2 pg/mL [76.1; 138.7]. Osteoporosis was present in 47.0% of patients. Distal 1/3 radius BMD was measured in 46.2%, identifying 11.4% with forearm-only osteoporosis. They were younger (60.6 ± 13.9 vs. 67.1 ± 10.2 years, p = 0.048), less frequently menopausal (66.7% vs. 95.9%, p = 0.001) and had higher calcium levels (2.88 ± 0.18 vs. 2.73 ± 0.20 mmol/L, p = 0.002) than the other osteoporotic patients. After surgery, BMD increased significantly at the lumbar spine (+0.06 g/cm2) and the total hip (+0.03 g/cm2), in a similar way to other osteoporotic patients.
Conclusion: After measuring distal 1/3 radius BMD, performed in < 50% of PHPT patients, it was identified that 11.4% patients had forearm-only osteoporosis, who could have a bone benefit from surgery. These findings emphasize the importance of systematic measurement during PHPT evaluation.
Trial registration: NCT05469087.
背景:原发性甲状旁腺功能亢进症(PHPT)患者推荐在腰椎、股骨颈、全髋关节和远端1/3桡骨处测量骨密度(BMD)。任何部位的骨质疏松都是手术的理由。桡骨远端1/3常被忽略。本研究评估了PHPT患者远端1/3桡骨测量的患病率、该部位骨质疏松的比例以及甲状旁腺切除术后1年的骨密度变化。方法:回顾2016年至2024年在法国南特大学医院中心接受甲状旁腺切除术的548例PHPT患者。没有术前腰椎或股骨颈骨密度测量的患者被排除在外。术前和术后12个月通过双x线骨密度仪评估骨密度。结果:纳入400例患者,平均年龄63.3±12.3岁,女性80.5%,绝经期86.2%。平均基线血钙为2.76±0.19 mmol/L;PTH中位数为99.2 pg/mL [76.1;138.7]。47.0%的患者存在骨质疏松症。测量远端1/3桡骨骨密度为46.2%,确定11.4%为前臂骨质疏松症。与其他骨质疏松患者相比,她们更年轻(60.6±13.9岁vs. 67.1±10.2岁,p = 0.048),绝经频率更低(66.7% vs. 95.9%, p = 0.001),钙水平更高(2.88±0.18 vs. 2.73±0.20 mmol/L, p = 0.002)。术后腰椎骨密度(+0.06 g/cm2)和全髋关节骨密度(+0.03 g/cm2)显著增加,与其他骨质疏松患者相似。结论:测量远端1/3桡骨骨密度后,进行试验注册:NCT05469087。
{"title":"Radius Bone Mineral Density Measurement Is Essential During Initial PHPT Workup: Results of a Retrospective Study on 400 Patients.","authors":"Mélanie Loison, Matthieu Wargny, Cécile Caillard, Pascale Guillot, Maëlle Le Bras, Bertrand Cariou, Claire Blanchard, Eric Mirallié, Samuel Frey","doi":"10.1002/wjs.70223","DOIUrl":"https://doi.org/10.1002/wjs.70223","url":null,"abstract":"<p><strong>Background: </strong>Bone mineral density (BMD) measurement at the lumbar spine, femoral neck, total hip, and distal 1/3 radius is recommended for patients with primary hyperparathyroidism (PHPT). Osteoporosis at any site justifies surgery. The distal 1/3 radius is often neglected. This study evaluated the prevalence of distal 1/3 radius measurement, the proportion of osteoporosis at this site alone, and BMD changes 1 year post-parathyroidectomy in patients with PHPT.</p><p><strong>Methods: </strong>A total of 548 patients who underwent parathyroidectomy for PHPT between 2016 and 2024 in University Hospital Center of Nantes (France) were reviewed. Patients without pre-surgery BMD measurements at the lumbar spine or the femoral neck were excluded. BMD was assessed via dual x-ray absorptiometry before and 12-months after surgery.</p><p><strong>Results: </strong>Four hundred patients (mean age 63.3 ± 12.3 years, 80.5% female, and 86.2% menopausal) were included. Mean baseline serum calcium was 2.76 ± 0.19 mmol/L; median PTH was 99.2 pg/mL [76.1; 138.7]. Osteoporosis was present in 47.0% of patients. Distal 1/3 radius BMD was measured in 46.2%, identifying 11.4% with forearm-only osteoporosis. They were younger (60.6 ± 13.9 vs. 67.1 ± 10.2 years, p = 0.048), less frequently menopausal (66.7% vs. 95.9%, p = 0.001) and had higher calcium levels (2.88 ± 0.18 vs. 2.73 ± 0.20 mmol/L, p = 0.002) than the other osteoporotic patients. After surgery, BMD increased significantly at the lumbar spine (+0.06 g/cm<sup>2</sup>) and the total hip (+0.03 g/cm<sup>2</sup>), in a similar way to other osteoporotic patients.</p><p><strong>Conclusion: </strong>After measuring distal 1/3 radius BMD, performed in < 50% of PHPT patients, it was identified that 11.4% patients had forearm-only osteoporosis, who could have a bone benefit from surgery. These findings emphasize the importance of systematic measurement during PHPT evaluation.</p><p><strong>Trial registration: </strong>NCT05469087.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconsidering the Clinical Feasibility of Venous Grafts for Bile Duct Replacement.","authors":"Seoung Hoon Kim","doi":"10.1002/wjs.70220","DOIUrl":"https://doi.org/10.1002/wjs.70220","url":null,"abstract":"","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145892630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Romulo Armenta-Flores, Diego Armenta-Villalobos, Luis G Domínguez-Carrillo
Background: Iliopsoas abscess (IPA), a purulent collection in the iliopsoas compartment, is an infrequent disease that is insidious, easily overlooked, life-threatening, and rarely diagnosed early due to nonspecific symptoms and signs. The classic triad of fever, flank pain, and hip movement limitation is present in only 30% of patients. Delays in treatment are followed by increased morbidity and mortality. The microbial etiology of IPA is variable and depends on the geographical area. IPA can be primary or secondary due to the origin of the infectious focus. This review aims to outline the current stage of knowledge of IPA, to emphasize its precocious recognition, and to provide a precise diagnosis using modern imaging according to the hospital patients are seen at, in an effort to reduce the delay in the diagnosis and treatment of IPA.
Methods: A comprehensive literature search was made from 1980 to December 2024 related to IPA published in English. Key words utilized were "iliopsoas abscess," "retroperitoneal infection," "psoas muscle disorder," "pyogenic psoas abscess," and "psoas abscess." A total of 247 papers were reviewed: 120 case reports, 33 short retrospective series of less than 15 patients, 20 large series with more than 50 patients, and 7 reviews. Additionally, 72 observational studies, 2 systematic reviews, and 2 prospective studies were reviewed. The inclusion criteria encompassed original and review articles published in English.
Conclusion: Since the description of IPA with isolated cases, then small series, and recently large retrospective reviews from major hospitals worldwide, the diagnosis and treatment of IPA have improved. With modern imaging techniques (US, CAT scan, and MRI), the diagnosis of IPA has increased, but sequential use of the aforementioned methods is not standardized; besides, there is no uniform treatment for IPA so far. Current management of IPA entails broad-spectrum antibiotics plus percutaneous or surgical drainage.
{"title":"Iliopsoas Abscess: A Narrative Review.","authors":"Romulo Armenta-Flores, Diego Armenta-Villalobos, Luis G Domínguez-Carrillo","doi":"10.1002/wjs.70213","DOIUrl":"https://doi.org/10.1002/wjs.70213","url":null,"abstract":"<p><strong>Background: </strong>Iliopsoas abscess (IPA), a purulent collection in the iliopsoas compartment, is an infrequent disease that is insidious, easily overlooked, life-threatening, and rarely diagnosed early due to nonspecific symptoms and signs. The classic triad of fever, flank pain, and hip movement limitation is present in only 30% of patients. Delays in treatment are followed by increased morbidity and mortality. The microbial etiology of IPA is variable and depends on the geographical area. IPA can be primary or secondary due to the origin of the infectious focus. This review aims to outline the current stage of knowledge of IPA, to emphasize its precocious recognition, and to provide a precise diagnosis using modern imaging according to the hospital patients are seen at, in an effort to reduce the delay in the diagnosis and treatment of IPA.</p><p><strong>Methods: </strong>A comprehensive literature search was made from 1980 to December 2024 related to IPA published in English. Key words utilized were \"iliopsoas abscess,\" \"retroperitoneal infection,\" \"psoas muscle disorder,\" \"pyogenic psoas abscess,\" and \"psoas abscess.\" A total of 247 papers were reviewed: 120 case reports, 33 short retrospective series of less than 15 patients, 20 large series with more than 50 patients, and 7 reviews. Additionally, 72 observational studies, 2 systematic reviews, and 2 prospective studies were reviewed. The inclusion criteria encompassed original and review articles published in English.</p><p><strong>Conclusion: </strong>Since the description of IPA with isolated cases, then small series, and recently large retrospective reviews from major hospitals worldwide, the diagnosis and treatment of IPA have improved. With modern imaging techniques (US, CAT scan, and MRI), the diagnosis of IPA has increased, but sequential use of the aforementioned methods is not standardized; besides, there is no uniform treatment for IPA so far. Current management of IPA entails broad-spectrum antibiotics plus percutaneous or surgical drainage.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145892662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-11-21DOI: 10.1002/wjs.70177
Maia R Nofal, Natnael Gebeyehu, Assefa Tesfaye, Habtamu Woldeamanuel, Senait Bitew Alemu, Sara Taye Haile, Tihitena Negussie Mammo, Thomas G Weiser
Introduction: Perioperative infection prevention and control (IPC) standards are known to reduce surgical site infections (SSI), but compliance is challenging. Clean Cut is a multimodal checklist-based quality improvement initiative to improve compliance with IPC standards. This study evaluates the impact of Clean Cut training workshops to improve IPC compliance when delivered as part of a bundled intervention.
Methods: From September 2021 to January 2023, nine Ethiopian hospitals received a bundled intervention that included educational workshops on the WHO Surgical Safety Checklist (SSC) and sterile reprocessing practices. Simultaneously, teams undertook a process mapping exercise of IPC standards to identify process gaps. We performed a time-series analysis to assess changes in compliance with the SSC, instrument, and linen reprocessing in the 4 months before and after the intervention. We calculated incidence rate ratios (IRR) of compliance and predicted the change in average weekly compliance.
Results: We observed 5821 operations, 2876 (49.4%) pre-intervention and 2946 (50.6%) post-intervention. Trends in SSC, instrument, and linen reprocessing compliance improved after the intervention. Average weekly SSC compliance improved 9.1% (RR: 1.09; 95% CI: 1.002-1.188; p = 0.044) while compliance with instrument reprocessing improved 12.1% (IRR: 1.12; 95% CI: 1.074-1.173; p < 0.001) and linen reprocessing 8.0% (IRR: 1.08, 95% CI: 1.017-1.147; p = 0.013).
Discussion: Workshop delivery coupled with process mapping of infection prevention standards was effective in improving compliance with the SSC and sterile reprocessing as part of a bundled intervention to reduce SSI. Observed improvements that temporally follow this work provide evidence of the value of this intervention.
{"title":"Sterile Reprocessing and Surgical Safety Checklist Training to Improve Perioperative Infection Prevention in Ethiopia.","authors":"Maia R Nofal, Natnael Gebeyehu, Assefa Tesfaye, Habtamu Woldeamanuel, Senait Bitew Alemu, Sara Taye Haile, Tihitena Negussie Mammo, Thomas G Weiser","doi":"10.1002/wjs.70177","DOIUrl":"10.1002/wjs.70177","url":null,"abstract":"<p><strong>Introduction: </strong>Perioperative infection prevention and control (IPC) standards are known to reduce surgical site infections (SSI), but compliance is challenging. Clean Cut is a multimodal checklist-based quality improvement initiative to improve compliance with IPC standards. This study evaluates the impact of Clean Cut training workshops to improve IPC compliance when delivered as part of a bundled intervention.</p><p><strong>Methods: </strong>From September 2021 to January 2023, nine Ethiopian hospitals received a bundled intervention that included educational workshops on the WHO Surgical Safety Checklist (SSC) and sterile reprocessing practices. Simultaneously, teams undertook a process mapping exercise of IPC standards to identify process gaps. We performed a time-series analysis to assess changes in compliance with the SSC, instrument, and linen reprocessing in the 4 months before and after the intervention. We calculated incidence rate ratios (IRR) of compliance and predicted the change in average weekly compliance.</p><p><strong>Results: </strong>We observed 5821 operations, 2876 (49.4%) pre-intervention and 2946 (50.6%) post-intervention. Trends in SSC, instrument, and linen reprocessing compliance improved after the intervention. Average weekly SSC compliance improved 9.1% (RR: 1.09; 95% CI: 1.002-1.188; p = 0.044) while compliance with instrument reprocessing improved 12.1% (IRR: 1.12; 95% CI: 1.074-1.173; p < 0.001) and linen reprocessing 8.0% (IRR: 1.08, 95% CI: 1.017-1.147; p = 0.013).</p><p><strong>Discussion: </strong>Workshop delivery coupled with process mapping of infection prevention standards was effective in improving compliance with the SSC and sterile reprocessing as part of a bundled intervention to reduce SSI. Observed improvements that temporally follow this work provide evidence of the value of this intervention.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"87-93"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145565728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}