Pub Date : 2022-12-22DOI: 10.21776/ub.mnj.2023.009.01.16
M. Husna, I. W. A. Wiyasa, Ria Damayanti, Syah Sembung Wasiso, Fahimma Fahimma, Kartika Agustina
Catamenial epilepsy refers to a seizure pattern that coincides with the menstrual period. Patients with catamenial epilepsy often leads to intractable epilepsy and may have an adverse impact on quality of life. Several medications are the therapeutic options, however, there is uncertainty regarding the best treatment, and these medications often fail to control the seizure. This makes catamenial epilepsy categorized as pharmaco-resistant epilepsy. This paper reported a case of perimenstrual catamenial epilepsy with an uncontrolled seizure problem. Seizures still occur with optimal management, and thereby clinicians must continue to re-evaluate clinical conditions and treatment selection to achieve optimal management. Personalized-based treatment should be considered in catamenial epilepsy management. This report discusses the challenges of catamenial epilepsy, understanding the catamenial process, and dealing with the problem with a practical personalized approach.
{"title":"DEALING WITH UNCONTROLLED SEIZURE IN CATAMENIAL EPILEPSY: A CASE REPORT","authors":"M. Husna, I. W. A. Wiyasa, Ria Damayanti, Syah Sembung Wasiso, Fahimma Fahimma, Kartika Agustina","doi":"10.21776/ub.mnj.2023.009.01.16","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.16","url":null,"abstract":"Catamenial epilepsy refers to a seizure pattern that coincides with the menstrual period. Patients with catamenial epilepsy often leads to intractable epilepsy and may have an adverse impact on quality of life. Several medications are the therapeutic options, however, there is uncertainty regarding the best treatment, and these medications often fail to control the seizure. This makes catamenial epilepsy categorized as pharmaco-resistant epilepsy. This paper reported a case of perimenstrual catamenial epilepsy with an uncontrolled seizure problem. Seizures still occur with optimal management, and thereby clinicians must continue to re-evaluate clinical conditions and treatment selection to achieve optimal management. Personalized-based treatment should be considered in catamenial epilepsy management. This report discusses the challenges of catamenial epilepsy, understanding the catamenial process, and dealing with the problem with a practical personalized approach.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124278465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.2
İsmail Karluka, H. Onan, E. Akgül, E. Aksungur
Background: There is no consensus on the duration of dual antiaggregant therapy after carotid stenting. This study aimed to evaluate the early contribution of dual antiaggregant therapy for three or six months to stent restenosis. Objective: This study aimed to identify the correlation between stent restenosis and the duration of dual antiplatelet therapy (DAPT) in carotid artery stenting (CAS) subjects by retrospectively scanning a CAS procedure dataset. Methods: Patients who underwent a CAS procedure received dual DAPT (acetylsalicylic acid (ASA) + clopidogrel) were recruited for this study. The first group was the patients who received dual antiaggregants for three months, and the second group was the patients who received dual antiaggregants for six months. Patients' demographic characteristics, comorbidities, and radiological results were reviewed. Follow-up activities for the following six months were assessed for stent status, complications, and new ischemic lesions. Results: A total of 65 patients received ASA (acetylsalicylic acid) + clopidogrel for six months, while the remaining 118 patients were treated for three months. The restenosis rates were not significantly different between the two groups. The complication and adverse event frequencies were also similar. Conclusion: This study revealed that the efficacy of 3-month and 6-month DAPT is similar regarding the restenosis frequency, and there are no significant differences in complication frequency.
{"title":"THE EFFECTS OF SHORT/LONG-TERM ADMINISTRATION OF DUAL ANTIPLATELET THERAPY ON RESTENOSIS IN PATIENTS WITH CAROTID ARTERY STENTING","authors":"İsmail Karluka, H. Onan, E. Akgül, E. Aksungur","doi":"10.21776/ub.mnj.2023.009.01.2","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.2","url":null,"abstract":"Background: There is no consensus on the duration of dual antiaggregant therapy after carotid stenting. This study aimed to evaluate the early contribution of dual antiaggregant therapy for three or six months to stent restenosis.\u0000Objective: This study aimed to identify the correlation between stent restenosis and the duration of dual antiplatelet therapy (DAPT) in carotid artery stenting (CAS) subjects by retrospectively scanning a CAS procedure dataset.\u0000Methods: Patients who underwent a CAS procedure received dual DAPT (acetylsalicylic acid (ASA) + clopidogrel) were recruited for this study. The first group was the patients who received dual antiaggregants for three months, and the second group was the patients who received dual antiaggregants for six months. Patients' demographic characteristics, comorbidities, and radiological results were reviewed. Follow-up activities for the following six months were assessed for stent status, complications, and new ischemic lesions.\u0000Results: A total of 65 patients received ASA (acetylsalicylic acid) + clopidogrel for six months, while the remaining 118 patients were treated for three months. The restenosis rates were not significantly different between the two groups. The complication and adverse event frequencies were also similar.\u0000Conclusion: This study revealed that the efficacy of 3-month and 6-month DAPT is similar regarding the restenosis frequency, and there are no significant differences in complication frequency.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116368797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.8
R. Pinzon, Nunki Puspita Utomo, Gabriel Pramono Btara Yudhitia
Despite the typical primary symptoms reported, the coronavirus disease 2019 (COVID-19) outbreak could be manifested as many symptoms. Neurological manifestations of COVID-19 are hypothesized to be caused by multiple pathophysiologies. As one of the possible prodromal symptoms in the absence of fever and respiratory symptoms, many individuals might be unaware of contracting COVID-19 infection and could possibly infect other people. This case series involved a hundred and twenty COVID-19 patients in which nine of them reported headaches as the chief complaint to provide the prevalence rate. Medical histories were assessed to provide the prevalence rate and laboratory findings of involved subjects. Narrative review of possible mechanisms of the manifestation were also denoted. To date, the proportion of non-specific manifestations as the first symptom needs to be further explored as it could be one of the initial symptoms and early manifestations of COVID-19.
{"title":"HEADACHE MANIFESTATION OF COVID-19: A CASE SERIES AND NARRATIVE REVIEW","authors":"R. Pinzon, Nunki Puspita Utomo, Gabriel Pramono Btara Yudhitia","doi":"10.21776/ub.mnj.2023.009.01.8","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.8","url":null,"abstract":"Despite the typical primary symptoms reported, the coronavirus disease 2019 (COVID-19) outbreak could be manifested as many symptoms. Neurological manifestations of COVID-19 are hypothesized to be caused by multiple pathophysiologies. As one of the possible prodromal symptoms in the absence of fever and respiratory symptoms, many individuals might be unaware of contracting COVID-19 infection and could possibly infect other people. This case series involved a hundred and twenty COVID-19 patients in which nine of them reported headaches as the chief complaint to provide the prevalence rate. Medical histories were assessed to provide the prevalence rate and laboratory findings of involved subjects. Narrative review of possible mechanisms of the manifestation were also denoted. To date, the proportion of non-specific manifestations as the first symptom needs to be further explored as it could be one of the initial symptoms and early manifestations of COVID-19.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124479665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.4
Liunardo Bintang Pratama, L. Amalia, Cep Juli, U. Gamayani, Asep Nugraha Hermawan
Background: Stroke is the second leading cause of death and the third cause of disability globally. Clinical outcomes caused by stroke are varied and influenced by various factors. Objective: This study aims to describe the clinical outcome of stroke patients based on neurological deficit using NIHSS at Dr. Hasan Sadikin General Hospital, Bandung. Methods: This study is a retrospective descriptive, cross-sectional study using secondary data from medical records recruited between January 2019 – December 2019 at the Department of Neurology Dr. Hasan Sadikin General Hospital Bandung with the total sampling method. Variables include demographic data, risk factors, and clinical characteristics. Neurological deficit was assessed using NIHSS. Data were analyzed and presented in the form of tables. Results: There were 202 subjects eligible for this study, including ischemic (71.8%) and intracerebral hemorrhage (28.2%) stroke patients. Most of the subjects were male (53%), aged ≥60 years (50,5%), presenting with onset >6 hours (72.3%), and had hypertension (92,1%). Most of the subjects have a moderate stroke (n=102;50.5%) based on the NIHSS score at admission and mild stroke (n=117;57.9%) based on the NIHSS score at discharge, with a motor deficit as the most common neurological deficit found. Conclusion: The majority of stroke patients presented with a moderate stroke on admission and had a clinical improvement during hospital treatment, with most of the patients experiencing a mild stroke on discharge based on NIHSS score. The motor deficit is the most common neurological deficit that affects clinical outcomes.
{"title":"CLINICAL OUTCOME OF STROKE PATIENTS BASED ON THE NATIONAL INSTITUTES OF HEALTH STROKE SCALE (NIHSS) IN A TERTIARY HOSPITAL","authors":"Liunardo Bintang Pratama, L. Amalia, Cep Juli, U. Gamayani, Asep Nugraha Hermawan","doi":"10.21776/ub.mnj.2023.009.01.4","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.4","url":null,"abstract":"Background: Stroke is the second leading cause of death and the third cause of disability globally. Clinical outcomes caused by stroke are varied and influenced by various factors.\u0000Objective: This study aims to describe the clinical outcome of stroke patients based on neurological deficit using NIHSS at Dr. Hasan Sadikin General Hospital, Bandung.\u0000Methods: This study is a retrospective descriptive, cross-sectional study using secondary data from medical records recruited between January 2019 – December 2019 at the Department of Neurology Dr. Hasan Sadikin General Hospital Bandung with the total sampling method. Variables include demographic data, risk factors, and clinical characteristics. Neurological deficit was assessed using NIHSS. Data were analyzed and presented in the form of tables.\u0000Results: There were 202 subjects eligible for this study, including ischemic (71.8%) and intracerebral hemorrhage (28.2%) stroke patients. Most of the subjects were male (53%), aged ≥60 years (50,5%), presenting with onset >6 hours (72.3%), and had hypertension (92,1%). Most of the subjects have a moderate stroke (n=102;50.5%) based on the NIHSS score at admission and mild stroke (n=117;57.9%) based on the NIHSS score at discharge, with a motor deficit as the most common neurological deficit found.\u0000Conclusion: The majority of stroke patients presented with a moderate stroke on admission and had a clinical improvement during hospital treatment, with most of the patients experiencing a mild stroke on discharge based on NIHSS score. The motor deficit is the most common neurological deficit that affects clinical outcomes.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117066085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.15
M. Dwitasari, D. Seputra
Ramsay Hunt Syndrome (RHS) is a rare disease caused by reactivation of latent Varicella Zoster Virus in the geniculate ganglion which lead to inflammation, edema, and compression of facial nerve. RHS may affect both immunocompetent and immunocompromised patient. Clinical manifestation of RHS include herpes zoster oticus that manifest as vesicular rash on auricular area or oral mucosa in combination with peripheral nerve palsy. We reported a 67-years-old female patient with herpetic vesicle on left side of face and ear accompanied with ipsilateral peripheral facial paralysis since 2 days before admission. Patient was treated with acyclovir for 5 days. Follow up examination showed satisfying clinical improvement with disappearance of vesicles and otalgia, as well as facial weakness improvement from House Brackmann grade III to grade II. Early recognition and treatment of Ramsay Hunt Syndrome is crucial as delay of treatment may lead to sequelae, including postherpetic neuralgia and permanent facial paralysis.
{"title":"RAMSAY HUNT SYNDROME: A CASE REPORT","authors":"M. Dwitasari, D. Seputra","doi":"10.21776/ub.mnj.2023.009.01.15","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.15","url":null,"abstract":"Ramsay Hunt Syndrome (RHS) is a rare disease caused by reactivation of latent Varicella Zoster Virus in the geniculate ganglion which lead to inflammation, edema, and compression of facial nerve. RHS may affect both immunocompetent and immunocompromised patient. Clinical manifestation of RHS include herpes zoster oticus that manifest as vesicular rash on auricular area or oral mucosa in combination with peripheral nerve palsy. We reported a 67-years-old female patient with herpetic vesicle on left side of face and ear accompanied with ipsilateral peripheral facial paralysis since 2 days before admission. Patient was treated with acyclovir for 5 days. Follow up examination showed satisfying clinical improvement with disappearance of vesicles and otalgia, as well as facial weakness improvement from House Brackmann grade III to grade II. Early recognition and treatment of Ramsay Hunt Syndrome is crucial as delay of treatment may lead to sequelae, including postherpetic neuralgia and permanent facial paralysis.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123975402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.11
Ziya Asan
Kernohan's notch phenomenon is a rare examination finding in cases diagnosed as an intracranial space-occupying lesion. The localization of the space-occupying lesion in this clinical status, which is considered as a sign of herniation, is on the opposite side of the predicted side. The most typical finding is motor deficit and mydriasis on the same side as the space-occupying lesion. A 61-year-old female patient was evaluated in the emergency department due to sudden loss of consciousness. Her neurological examination revealed anisocoria and right hemiparesis findings, including mydriasis in the right pupil. Cranial computed tomography examination revealed a large, acute component combined with chronic subdural hematoma in the right frontoparietal region and midline shift. Clinical and radiological findings were evaluated as Kernohan’s Notch Sign phenomenon. The patient, who was operated on urgently, was discharged on the 7th postoperative day without any neurological deficits.
{"title":"KERNOHAN’S NOTCH PHENOMENON IN AN ACUTE COMPONENTED CHRONIC SUBDURAL HEMATOMA PATIENT: A CASE REPORT","authors":"Ziya Asan","doi":"10.21776/ub.mnj.2023.009.01.11","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.11","url":null,"abstract":"Kernohan's notch phenomenon is a rare examination finding in cases diagnosed as an intracranial space-occupying lesion. The localization of the space-occupying lesion in this clinical status, which is considered as a sign of herniation, is on the opposite side of the predicted side. The most typical finding is motor deficit and mydriasis on the same side as the space-occupying lesion. A 61-year-old female patient was evaluated in the emergency department due to sudden loss of consciousness. Her neurological examination revealed anisocoria and right hemiparesis findings, including mydriasis in the right pupil. Cranial computed tomography examination revealed a large, acute component combined with chronic subdural hematoma in the right frontoparietal region and midline shift. Clinical and radiological findings were evaluated as Kernohan’s Notch Sign phenomenon. The patient, who was operated on urgently, was discharged on the 7th postoperative day without any neurological deficits.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122884176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.6
Lutpyah L, Arthur Hendrik Philips Mawuntu, Hamdana H, Mieke Actrees Hanna Nelly Kembuan
Background: The COVID-19 vaccination can relate to the occurrence of neurological adverse events following immunization (AEFI) that could impact work and daily activities. This problem is particularly important in the health workforce. However, little is known about neurological AEFI among the health workforce working in peripheral facilities. Objective: To study the neurological AEFIs and their impact among the health workforce who received the COVID-19 vaccination in a secondary referral hospital in South Sulawesi, the Andi Makassau Hospital (Rumah Sakit Umum Daerah Andi Makassau/RSAM). Methods: The COVID-19 pandemic, we created a questionnaire about neurological AEFIs and their effects which were distributed online using the Google Form application to the health workforce at the RSAM who had received at least one dose of COVID-19 vaccination. Results: We obtained 97 subjects. There were 78.5% neurological AEFIs with the most reported type being muscle pain (16%). Most neurological AEFIs were experienced by women (84.9%), age group 21-35 years (53.8%), and non-doctors/nurses (60.8%). The significant influencing factors in multivariate analysis were age group 36-45 years (p = 0.04), nursing proffesion (p = 0.005), and non- viral-based baccine type (p = < 0.0001). Conclusion: Neurological AEFI is commonly found among the health workforce who received the COVID-19 vaccination. However, it only has a little impact on their work and attitudes towards vaccination. This may be because all subjects experienced mild neurological AEFI.
背景:COVID-19疫苗接种可能与免疫后神经系统不良事件(AEFI)的发生有关，可能影响工作和日常活动。这一问题在卫生人力中尤为重要。然而，在外围设施工作的卫生工作者中，对神经系统急性脑损伤知之甚少。目的:研究南苏拉威西省二级转诊医院Andi Makassau医院(Rumah Sakit Umum Daerah Andi Makassau/RSAM)接受COVID-19疫苗接种的卫生工作者的神经系统不良反应及其影响。方法:在COVID-19大流行期间，我们制作了一份关于神经系统AEFIs及其效果的调查问卷，并使用Google Form应用程序在线分发给至少接种过一剂COVID-19疫苗的RSAM卫生工作者。结果:共纳入97例受试者。78.5%为神经性急性脑损伤，其中肌肉疼痛类型最多(16%)。大多数神经系统急性脑损伤患者为女性(84.9%)、21-35岁年龄组(53.8%)和非医生/护士(60.8%)。多因素分析的显著影响因素为年龄36 ~ 45岁(p = 0.04)、护理专业(p = 0.005)、非病毒型疫苗(p = < 0.0001)。结论:神经性急性脑损伤常见于接种COVID-19疫苗的卫生工作者。然而，这对他们的工作和对疫苗接种的态度只有很小的影响。这可能是因为所有受试者都经历了轻度神经性急性脑损伤。
{"title":"NEUROLOGICAL ADVERSE EVENTS FOLLOWING IMMUNIZATION (AEFI) ON HEALTH WORKFORCE OF A SECONDARY REFERRAL HOSPITAL IN SOUTH SULAWESI WHO RECEIVED THE","authors":"Lutpyah L, Arthur Hendrik Philips Mawuntu, Hamdana H, Mieke Actrees Hanna Nelly Kembuan","doi":"10.21776/ub.mnj.2023.009.01.6","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.6","url":null,"abstract":"Background: The COVID-19 vaccination can relate to the occurrence of neurological adverse events following immunization (AEFI) that could impact work and daily activities. This problem is particularly important in the health workforce. However, little is known about neurological AEFI among the health workforce working in peripheral facilities.\u0000Objective: To study the neurological AEFIs and their impact among the health workforce who received the COVID-19 vaccination in a secondary referral hospital in South Sulawesi, the Andi Makassau Hospital (Rumah Sakit Umum Daerah Andi Makassau/RSAM).\u0000Methods: The COVID-19 pandemic, we created a questionnaire about neurological AEFIs and their effects which were distributed online using the Google Form application to the health workforce at the RSAM who had received at least one dose of COVID-19 vaccination.\u0000Results: We obtained 97 subjects. There were 78.5% neurological AEFIs with the most reported type being muscle pain (16%). Most neurological AEFIs were experienced by women (84.9%), age group 21-35 years (53.8%), and non-doctors/nurses (60.8%). The significant influencing factors in multivariate analysis were age group 36-45 years (p = 0.04), nursing proffesion (p = 0.005), and non- viral-based baccine type (p = < 0.0001).\u0000Conclusion: Neurological AEFI is commonly found among the health workforce who received the COVID-19 vaccination. However, it only has a little impact on their work and attitudes towards vaccination. This may be because all subjects experienced mild neurological AEFI.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123133014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.5
Richard Suherlim, Nyoman Angga Krishna Pramana, K. Tini, Ida Bagus Kusuma Putra, Ida Ayu Sri Indrayani
Background: Ischemic stroke account for about 87% of all stroke cases. This study will focus on ischemic stroke due to small vessel occlusion as one of the subtypes based on TOAST (trial of ORG 10172 in acute stroke treatment). Objective: To determine the characteristics of ischemic stroke patients caused by small vessel occlusion and are expected to be used as a basis for further research. Methods: A descriptive observational retrospective study regarding the characteristics of acute ischemic stroke patients due to small vessel occlusion at Sanglah Hospital. Secondary data were obtained from patient medical records. Results: The total number of cases of small vessel occlusion was 338. The majority of the sample were men (64.5%) between 40-60 years old (53.6%). Most of the samples were patients who had experienced an ischemic stroke for the first time (75.1%) with NIHSS (National Institute of Health Stroke Scale) scores showing mild (48.2%) and moderate (51.5%) symptoms. Around half of them had a history of hypertension (60.1%), dyslipidemia (59.5%), and diabetes mellitus (44.1%). The most common location of infarction was in the anterior circulation (77.5%) with almost the same ratio of right and left hemisphere locations. Conclusion: Ischemic stroke due to occlusion of small vessels at Sanglah Hospital Denpasar for 3 years was 35.2% of the total ischemic stroke cases. Half of the total sample had classic vascular risk factors. Further research is needed to determine another effective treatment strategy other than just secondary prevention such as life style moderation to prevent recurrency.
{"title":"CHARACTERISTICS OF ACUTE ISCHEMIC STROKE PATIENTS DUE TO SMALL VESSEL OCCLUSION","authors":"Richard Suherlim, Nyoman Angga Krishna Pramana, K. Tini, Ida Bagus Kusuma Putra, Ida Ayu Sri Indrayani","doi":"10.21776/ub.mnj.2023.009.01.5","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.5","url":null,"abstract":"Background: Ischemic stroke account for about 87% of all stroke cases. This study will focus on ischemic stroke due to small vessel occlusion as one of the subtypes based on TOAST (trial of ORG 10172 in acute stroke treatment).\u0000Objective: To determine the characteristics of ischemic stroke patients caused by small vessel occlusion and are expected to be used as a basis for further research.\u0000Methods: A descriptive observational retrospective study regarding the characteristics of acute ischemic stroke patients due to small vessel occlusion at Sanglah Hospital. Secondary data were obtained from patient medical records.\u0000Results: The total number of cases of small vessel occlusion was 338. The majority of the sample were men (64.5%) between 40-60 years old (53.6%). Most of the samples were patients who had experienced an ischemic stroke for the first time (75.1%) with NIHSS (National Institute of Health Stroke Scale) scores showing mild (48.2%) and moderate (51.5%) symptoms. Around half of them had a history of hypertension (60.1%), dyslipidemia (59.5%), and diabetes mellitus (44.1%). The most common location of infarction was in the anterior circulation (77.5%) with almost the same ratio of right and left hemisphere locations.\u0000Conclusion: Ischemic stroke due to occlusion of small vessels at Sanglah Hospital Denpasar for 3 years was 35.2% of the total ischemic stroke cases. Half of the total sample had classic vascular risk factors. Further research is needed to determine another effective treatment strategy other than just secondary prevention such as life style moderation to prevent recurrency.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116378084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.10
Ziya Asan
Arachnoid cysts occur in approximately 1% of all intracranial space-occupying lesions and do not require a very high rate of surgical intervention. Arachnoid cysts are cystic formations containing cerebrospinal fluid. It is argued that the enlargement of the arachnoid cysts increases in volume with the unilateral valve mechanism. They are generally considered static formations because they do not tend to grow. A 16-year-old male patient was evaluated for headache attacks resistant to medical treatment. A giant arachnoid cyst located in the left temporal region was detected in the cranial MRI examination of the patient who had no history of head trauma or cranial operation in his medical history. In the MRI examination two years later, it was seen that the arachnoid cyst had almost completely disappeared. However, it was also found that it caused cambering in the temporal bone in the adjacent region. This finding supports that not all arachnoid cysts are static formations; they may have their internal dynamics and even cause shape changes in the surrounding tissues and even the cranium.
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Pub Date : 2022-12-20DOI: 10.21776/ub.mnj.2023.009.01.12
A. Stella, Gkantzios Aimilios, Kourtesis Ioannis, Samaras Nikolasos, Barmpari Athanasia, Filippi Aikaterini, T. Jupe, Kosta Natalia, Maltezou Maria
We present a case of combined central and peripheral demyelination in a patient with pediatric multiple sclerosis after the first dose of ChAdOx1-S (Chimpanzee Adenovirus Oxford 1) vaccination. The patient presented with ascending flaccid quadriparesis with respiratory failure that required mechanical ventilation. The lumbar puncture revealed albuminocytological dissociation, was negative for presence of JCV (John Cunningham Virus) in the CSF (Cerebrospinal Fluid) and ruled out other infections. A few days later he developed anisocoria and multiple new enlarging acute demyelinating lesions in the brain MRI (Magnetic Resonance Imaging). He was treated with intravenous immunoglobulin, corticosteroids and plasma exchange with gradual improvement. All other diseases were excluded via MR Spectroscopy, MR Angiography and serum and CSF laboratory investigations. Seven months later, the patient is under intense physiotherapy and is improving every day.
{"title":"A CASE OF COMBINED CENTRAL AND PERIPHERAL DEMYELINATION IN A PATIENT WITH PEDIATRIC MULTIPLE SCLEROSIS AFTER SARS-COV-2 VACCINATION","authors":"A. Stella, Gkantzios Aimilios, Kourtesis Ioannis, Samaras Nikolasos, Barmpari Athanasia, Filippi Aikaterini, T. Jupe, Kosta Natalia, Maltezou Maria","doi":"10.21776/ub.mnj.2023.009.01.12","DOIUrl":"https://doi.org/10.21776/ub.mnj.2023.009.01.12","url":null,"abstract":"We present a case of combined central and peripheral demyelination in a patient with pediatric multiple sclerosis after the first dose of ChAdOx1-S (Chimpanzee Adenovirus Oxford 1) vaccination. The patient presented with ascending flaccid quadriparesis with respiratory failure that required mechanical ventilation. The lumbar puncture revealed albuminocytological dissociation, was negative for presence of JCV (John Cunningham Virus) in the CSF (Cerebrospinal Fluid) and ruled out other infections. A few days later he developed anisocoria and multiple new enlarging acute demyelinating lesions in the brain MRI (Magnetic Resonance Imaging). He was treated with intravenous immunoglobulin, corticosteroids and plasma exchange with gradual improvement. All other diseases were excluded via MR Spectroscopy, MR Angiography and serum and CSF laboratory investigations. Seven months later, the patient is under intense physiotherapy and is improving every day.","PeriodicalId":247353,"journal":{"name":"MNJ (Malang Neurology Journal)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123358683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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