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Methods of analysis of encephalograph signals using neural networks 用神经网络分析脑电图信号的方法
Pub Date : 2021-12-21 DOI: 10.1117/12.2617392
Dmytro M. Kartolapov, V. O. Novikov, S. Tymchyk, Olga V. Akimova, Natalia A. Bouhlal
In this paper, a system for read-out sensing and analyzing human brain signals using an encephalograph is considered.Characteristics of human brain signals are considered. Based on this system it is proposed to create a neuro-interface in which the received signals will be analyzed by neural networks.
本文研究了一种利用脑电图仪读出、感知和分析人脑信号的系统。考虑了人脑信号的特征。在此基础上,提出了一个神经接口,通过神经网络对接收到的信号进行分析。
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引用次数: 0
Detection of pathological changes in the architectonics of polycrystalline blood films using laser-induced polarization interferometry 激光诱导偏振干涉法检测多晶血膜结构病理变化
Pub Date : 2021-12-21 DOI: 10.1117/12.2616837
D. Kvasnyuk, L. Trifonyuk, A. Strashkevich, N. Kozan, V. Ushenko, O. Dunaiev, V. Kryvetskiy, I. Oliinyk, E. Kurek, V. Tkachuk
The paper presents the results of the possibility of a polarization-interference approach to the analysis of microscopic images polycrystalline blood films of patients of benign and malignant prostate tumours with different degrees of differentiation. Measurements and analysis of maps and histograms of the distribution of the local contrast value of polarization-interference distributions of microscopic images of polycrystalline blood films of patients . Determination of the relationship between the statistical moments of the 1st - 4th orders characterizing the distributions of the local contrast value of the polarization-interference distributions of microscopic images of polycrystalline blood films of patients. Determination of statistical criteria for polarization-interference diagnosis of histological sections of biopsy of adenoma and adenocarcinoma with varying degrees of differentiation. Determination of sensitivity, specificity, accuracy of the polarization interferometry method for differential diagnosis of polycrystalline blood films of patients of adenoma and adenocarcinoma with varying degrees of differentiation.
本文介绍了偏振干涉法对不同分化程度的前列腺良恶性肿瘤患者的显微图像多晶血膜进行分析的可能性。患者多晶血膜显微图像偏振干涉分布局部对比值分布图和直方图的测量与分析。确定表征患者多晶血膜显微图像偏振干涉分布局部对比值分布的1 - 4阶统计矩之间的关系。不同分化程度的腺瘤和腺癌活检组织学切片偏振干涉诊断的统计标准的确定。极化干涉法鉴别诊断腺瘤和不同分化程度腺癌患者多晶血膜的灵敏度、特异性和准确性的测定
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引用次数: 1
Features of the use of polarized radiation to assess the structural organization of light-scattering objects 利用偏振辐射评价光散射物体结构组织的特点
Pub Date : 2021-12-21 DOI: 10.1117/12.2615771
L. Pidkamin, A. Arkhelyuk, Y. Dobrovolskii
The features of the use of polarized radiation in the problems of metrology of optical-geometric and structural parameters of light-scattering objects of various physical and chemical nature are described. Experimental situations are revealed that are most relevant for the study of optically anisotropic dispersed media containing particles of various shapes, sizes and orientations. The analytical dependence of the value of the fourth Stokes parameter of circularly polarized radiation passing through a layer of oriented particles with an optical thickness τ < 3 on the degree of their orientation is determined. A method is proposed for assessing the degree of orientation of macromolecules in polymer films, the conformation of biopolymers from the values of f22 components at any scattering angles, and determining the shape of macromolecules at scattering angles greater than α > 30°. Experimental conditions and methods of matrix polarimetry of the process of corrosion of the free surface of a metal and its corrosion under a paint-and-lacquer coating are presented.
叙述了偏振辐射在各种物理和化学性质的光散射物体的光学几何和结构参数计量问题中的应用特点。揭示了包含不同形状、大小和取向的粒子的光学各向异性分散介质的实验情况。确定了圆偏振辐射穿过光学厚度τ < 3的取向粒子层时,第四Stokes参数的值与取向程度的解析依赖关系。本文提出了一种评估高分子薄膜中大分子取向程度的方法,并从任意散射角下f22组分的值来确定生物聚合物的构象,以及确定散射角大于α > 30°时大分子形状的方法。本文介绍了金属自由表面腐蚀过程的实验条件和方法,以及金属在油漆和真漆涂层下的腐蚀过程。
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引用次数: 0
Polymer-dispersed liquid crystals forming tunable microlens 聚合物分散液晶形成可调谐微透镜
Pub Date : 2021-12-21 DOI: 10.1117/12.2615163
P. Maksimyak, A. Maksimyak, A. Nehrych
At present, liquid crystals – polymer (LC-P) composites such as polymer-dispersed liquid crystals (PDLC), polymer stabilized liquid crystals (PSLC) and polymer networks in liquid crystals (PNLC) are widely used as operating elements of optical devices such as microlens and elements, whose principle of operation is based on light scattering. LC-P composites light refraction features depend on shape and size of liquid crystal (LC) drops as well as on director orientation inside of drops. LC anisotropy influences polarization characteristics of refracted radiation. We have investigated desined as the tunable microlens on LC-P with different components concentration ratio. We have used LC E7 by Merck, dispersed in the polymer NOA 65 by Norland Inc. as the object of research. They have close refractive indeces which provide the posibility to shange the focal length of such LC lens in wide range. We change focal length by change of applied voltage and by rotation of polarization plane of illuminating beam. Partial beams passed through LC droplets and polymer matrix may be considered as plane waves passing different optical pathes and interfering in the far zone. Changing the voltage results in changing the LC effective refractive index leading to a change of the path difference between the interfering beams. The effect of interference decreases of some spectral components of the radiation passing through LC-P sample can be used as a tunable chromatic lens.
目前,聚合物分散液晶(PDLC)、聚合物稳定液晶(PSLC)、液晶中聚合物网络(PNLC)等液晶-聚合物(LC-P)复合材料被广泛应用于微透镜、微元件等光学器件的工作元件,其工作原理基于光散射。LC- p复合材料的光折射特性不仅与液晶液滴的形状和大小有关,还与液滴内部的定向方向有关。LC的各向异性影响折射辐射的偏振特性。我们研究了在不同组分浓度比的LC-P上设计可调微透镜。我们以分散在Norland公司的聚合物noa65中的默克公司的LC E7作为研究对象。它们具有较近的折射率,这为在大范围内改变这种LC透镜的焦距提供了可能。通过改变外加电压和照明光束偏振面旋转来改变焦距。通过LC液滴和聚合物基体的部分光束可以看作是通过不同光路的平面波,在远区发生干涉。电压的改变导致LC有效折射率的改变,从而导致干涉光束间程差的变化。通过LC-P样品的辐射中某些光谱成分的干涉减少效应可以用作可调色度透镜。
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引用次数: 0
Mueller-matrix microscopy of laser-induced monochromatic fluorescent fields of preparations of human internal organs and histological diagnostics of the time of age of damage formation 米勒基质显微镜下激光诱导单色荧光场对人体内脏器官的制备及年龄损伤形成的组织学诊断
Pub Date : 2021-12-21 DOI: 10.1117/12.2616667
A. Litvinenko, D. Kvasnyuk, A. Y. Vanchulyak, M. Stashkevich, A. Motrich, A. Y. Mikhailova, M. P. Gorskiy, M. Slyotov
The article contains the results of experimental testing of methods of azimuthal-invariant Mueller-matrix microscopy (Mueller-matrix invariants - MMI) of optically anisotropic fluorophores of samples of histological sections of the brain, liver and kidney, as well as myocardium and lung tissue; temporal detection of variations in the magnitude of the statistical moments of the 1st - 4th orders, characterizing the distributions of the MMI value of linear birefringence and optical activity of samples of histological sections of the brain, liver and kidney, as well as myocardium and lung tissue with different age of damage; determination of the diagnostic efficiency (time interval and accuracy) of establishing the age of damage to human internal organs by digital histological methods of MMI mapping of optical anisotropy of fluorophores in histological sections of the brain, liver and kidney, as well as myocardium and lung tissue.
本文介绍了对脑、肝、肾、心肌和肺组织的组织学切片样品的光学各向异性荧光团的方位不变穆勒矩阵显微镜(Mueller-matrix invariants - MMI)方法的实验测试结果;时间检测1 - 4阶统计矩量的变化,表征脑、肝、肾以及不同损伤年龄的心肌和肺组织的组织学切片样品的线性双折射MMI值和光学活性的分布;测定脑、肝、肾、心肌和肺组织组织切片荧光团光学各向异性的MMI数字组织学方法建立人体内脏器官损伤年龄的诊断效率(时间间隔和准确性)。
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引用次数: 0
Simulation of wavefront shaping through scattering media 散射介质对波前整形的模拟
Pub Date : 2021-12-21 DOI: 10.1117/12.2615557
V. Danko, O. Danko, A. Kovalenko
Wavefront shaping technique makes it possible to overcome limitations for optical imaging in strongly scattering media. Various wavefront shaping algorithms are used in order to find an optimal incident optical field. However, in many cases such experiments appear to be very time consuming and suffer from instability of the scattering media. So, it seems reasonable to use computer simulation in this field. In this paper we use two different approaches to simulate the light focusing through scattering media. The first approach consists in numerical solution of Maxwell equations for the set of spherical particles in random positions, which represent the scattering media. The result of the solution represents the scattering matrix of the media. This matrix is used to simulate propagation of spatially modulated light in the “frozen” stochastic media. As entries of the scattering matrix appear to be random variables with Gaussian distribution, they could be set heuristically for modeling purposes. This makes possible modeling of the wavefront shaping with large number of orthogonal modes of incident light. We considered four focusing techniques: continuous sequential algorithm and focusing using useful properties of Hadamard matrix with a phase-only and binary amplitude modulation (BAM). We represent results on convergence of the algorithms and focal intensity enhancement. We examined spatial variations of intensity enhancement, while scanning the focal point in observation plane. We found, that the intensity enhancement strongly correlates with the speckle from unmodulated illumination, when the BAM is used for wavefront shaping. In the case of phase-only modulation, only weak correlations were observed.
波前整形技术使得克服强散射介质中光学成像的局限性成为可能。为了找到最优的入射光场,使用了各种波前整形算法。然而,在许多情况下,这样的实验显得非常耗时,并受到散射介质的不稳定性的影响。因此,在这一领域使用计算机模拟似乎是合理的。本文采用两种不同的方法来模拟光在散射介质中的聚焦。第一种方法是对代表散射介质的随机位置的球形粒子集进行麦克斯韦方程组的数值求解。解的结果表示介质的散射矩阵。该矩阵用于模拟空间调制光在“冻结”随机介质中的传播。由于散射矩阵的条目似乎是高斯分布的随机变量,因此可以启发式地设置它们以进行建模。这使得用大量的入射光的正交模式来建模波前整形成为可能。我们考虑了四种聚焦技术:连续顺序算法和利用Hadamard矩阵的有用性质与相位和二进制调幅(BAM)聚焦。我们给出了算法收敛性和聚焦强度增强的结果。在观测平面上对焦点进行扫描的同时,研究了强度增强的空间变化。我们发现,当BAM用于波前整形时,强度增强与非调制照明产生的散斑密切相关。在纯相位调制的情况下,只观察到弱相关性。
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引用次数: 0
Polarization phase reconstruction phase anisotropy in diagnostics of the polycrystalline structure of acrylic glass 偏振相位重建与相位各向异性在丙烯酸玻璃多晶结构诊断中的应用
Pub Date : 2021-12-21 DOI: 10.1117/12.2617045
O. Dubolazov, O. Ushenko, A. Motrich, M. Gavrylyak, I. Soltys, O. Olar, M. Slyotov, M. Matymish
Algorithms for reconstruction of linear and circular birefringence of optically thin anisotropic акрилового скла layers are presented. The technique of Jones-matrix tomography of polycrystalline acrylic glass layers has been experimentally tested. The coordinate distributions of phase anisotropy of acrylic glass samples with varying degrees of mechanical stress are determined and statistically analyzed. Criteria (statistical moments of 3rd and 4th orders) of differential diagnostics of the presence of mechanical stress were determined.
提出了线性和圆形双折射光薄各向异性акрилового скла层的重建算法。对多晶丙烯酸玻璃层的琼斯矩阵层析技术进行了实验测试。测定了不同机械应力下丙烯酸玻璃样品相各向异性的坐标分布,并进行了统计分析。确定了机械应力存在的鉴别诊断标准(3阶和4阶统计矩)。
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引用次数: 0
Charge inversion of polarization correlation vortex 极化相关涡旋的电荷反演
Pub Date : 2021-12-21 DOI: 10.1117/12.2615150
Himangi J Pandit, Vijay Kumar, R. P. Singh
Optical Speckles has many extraordinary applications like subwavelength focusing, aberration-free imaging, etc. which are not possible even with a highly coherent optical field. This makes it necessary to study the fundamental properties of such Optical Speckle fields. In the recent past, the polarization correlation vortex phase was experimentally realized in vector speckle field generated by scattering of Poincare beam. Higher-order correlations have also been studied in such vector speckle fields. Moving further into this direction, we have studied the first-order polarization correlations in the focused vector speckle field. We have generated a vector speckle field by scattering of Poincare beam. Which is then allowed to be focused using a spherical and a cylindrical lens. The focused vector speckle field intensities at different planes around the focal plane were recorded to get polarization correlations at each plane. It was observed that the charge of the input vortex beam before scattering is still present in the polarization correlation of the focused vector speckle field. We have also observed charge inversion of polarization correlation vortex focused through a cylindrical lens. The importance of this study relies in the fact that it provides, with supporting experimental and simulation results, that the polarization correlation obeys the wave equation. It could find application in optical image processing while analyzing any optical data, to find information about the source of the speckles, etc.
光学斑点有许多非凡的应用,如亚波长聚焦,无像差成像等,这是不可能的,即使是高度相干的光场。因此,有必要研究这种光学散斑场的基本性质。近年来,在庞加莱光束散射产生的矢量散斑场中,实验实现了偏振相关涡相位。在这种矢量散斑场中也研究了高阶相关性。在此基础上,我们进一步研究了聚焦矢量散斑场的一阶偏振相关。我们利用庞加莱光束的散射产生了一个矢量散斑场。然后用球面透镜和圆柱透镜聚焦。记录焦平面周围不同平面上的聚焦矢量散斑场强度,得到各平面上的偏振相关性。观察到在聚焦矢量散斑场的偏振相关中,输入涡旋光束在散射前的电荷仍然存在。我们还观察到偏振相关涡旋通过圆柱透镜聚焦后的电荷反转。这项研究的重要性在于,它提供了支持的实验和模拟结果,即偏振相关服从波动方程。它可以应用于光学图像处理,分析任何光学数据,查找散斑的来源信息等。
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引用次数: 0
Spectrophotometry of native cytological smears from the cervix in cervical cancer screening 子宫颈细胞学涂片分光光度法在宫颈癌筛查中的应用
Pub Date : 2021-12-21 DOI: 10.1117/12.2615512
O. Peresunko, Ju. Galushko, P. Riabyi, N. Horodynska, S. Yermolenko, D. Burkovets, K. Chala
The aim of this work is to improve the diagnosis of cervical cancer by introducing laser polarimetry and spectro polarization methods of investigation. We have proposed a novel approach for the differentiation of squamous cell carcinoma and cervical adenocarcinoma using laser optics. Obtained by the method of laser polarimetry by Stokes parameter S4 of native smear with adenocarcinoma of the cervix and squamous cell carcinoma, as well as scraping of the mud canal with endometrial adenocarcinoma and flat cell cancer allows to reliably differentiate the norm from cancer in the native smear and adenocarcinoma from the flat cell cancer in the smear-imprint. The method of spectropolarimetry allows reliably accurately distinguishing the normal epithelium of the cervix from cancer of the cervix, and the parameters of linear dichroism during the spectropolarization study, reliably (р=0,001) differentiate between normal, adenocarcinoma and flat cell cancer of the cervix.
本工作的目的是通过引入激光偏振法和光谱偏振法的调查来提高宫颈癌的诊断。我们提出了一种新的方法来鉴别鳞状细胞癌和宫颈腺癌的激光光学。采用Stokes参数S4激光偏振法对宫颈腺癌和鳞状细胞癌的原生涂片,以及子宫内膜腺癌和扁平细胞癌的泥管刮削,可以可靠地区分原生涂片中的正常癌和扁平细胞癌,以及涂片印记中的腺癌和扁平细胞癌。光谱偏振法可以可靠准确地区分宫颈正常上皮和宫颈癌,光谱偏振研究中的线性二色性参数可以可靠地区分宫颈正常上皮、腺癌和扁平细胞癌(0.01)。
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引用次数: 0
Transmission of phase informative optical signal through the optically inhomogeneous medium 相位信息光信号在光非均匀介质中的传输
Pub Date : 2021-12-21 DOI: 10.1117/12.2615216
L. Derzhypolska, A. Derzhypolskyi, O. Gnatovskyi
In the paper described is a method of transmission of phase information by an optical signal which propagates through an optically inhomogeneous medium. Phase information is represented as an interference pattern of two states of an object that is deformed between state fixations. It is proposed to pass signal and reference beams through an optically inhomogeneous path in the same direction when recording holograms of states. In this implementation, an optical signal which carries information in the form of a system of interfering beams (holograms) is subject to minimal interference. And these holograms contain undistorted information about the wavefronts of the beams. Further mathematical processing (image addition and noise separation) allows to obtain the desired information about the deformation of the object. Optical inhomogeneities in the work are represented in thin diffuser approximation (Random Phase Diffuser), where RPD is described as an ensemble of point retranslates. Each of these retranslates at any point of the cross section of the beam transmit the amplitude of the field and at the same time adds a random stationary change to the phase. This model of optical inhomogeneities is of practical interest, because such a representation corresponds to the description of a single-mode regular fiber bundle, which can be used in real experiments to obtain information about the state of the object from hard-to-reach places.
本文描述了光信号在非均匀介质中传输相位信息的一种方法。相位信息表示为在状态固定之间变形的物体的两种状态的干涉图案。提出了在记录状态全息图时,信号和参考光束沿同一方向通过非均匀光路的方法。在这种实现中,以干涉光束(全息图)系统的形式携带信息的光信号受到最小的干扰。这些全息图包含了关于光束波前的未失真信息。进一步的数学处理(图像添加和噪声分离)允许获得关于物体变形的所需信息。工作中的光学不均匀性用薄扩散器近似(随机相位扩散器)表示,其中RPD被描述为点重平移的集合。在光束横截面的任何一点上,这些重新转换的每一个都传递了场的振幅,同时给相位增加了一个随机的平稳变化。这种光学非均匀性模型具有实际意义,因为这种表示对应于单模规则光纤束的描述,可以在实际实验中用于从难以到达的地方获得有关物体状态的信息。
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引用次数: 0
期刊
International Conference on Correlation Optics
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