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Clinico-demographic profile of patients treated for Tuberculous Lymphadenitis at the Central Chest Clinic, Colombo, Sri Lanka 斯里兰卡科伦坡中央胸科诊所治疗结核性淋巴结炎患者的临床人口统计资料
Pub Date : 2018-12-31 DOI: 10.4038/CJMS.V55I2.4955
N. Amarasinghe, A. Fernando, A. Sadikeen, T. Perera, Ghazzaly Nizamdeen, D. Jayamanne, S. Nanayakkara
Background: Tuberculous lymphadenitis (TBLN) is the commonest form of extra-pulmonary tuberculosis in Sri Lanka. The management of TBLN faces many challenges due to difficulty in achieving microbiological confirmation as well as slow or paradoxical clinical response during the treatment. Objective: To describe the demographic features and the characteristics associated with clinical presentation, diagnostic modalities and treatment outcome of patients with TBLN. Method: An audit was carried out revising clinical records of patients treated for peripheral lymph node enlargement due to tuberculosis at the Central Chest Clinic, Colombo.   Results: A total of 126 clinical records were analysed. The male:female ratio was 1:1.6 with a mean age of 36 years (SD=17.6). The most affected site were the cervical lymph nodes (94%). Mantoux test positivity (>10mm) was detected in 87.5%.  Evidence of granulomatous inflammation in primary investigations was seen in 122 (97%) of patients. Out of all only 12 (9.5%) were microbiologically confirmed including 5 culture positives. The rest of the patients (90.5%) were diagnosed based on supportive primary and ancillary diagnostic tests. Paradoxical reactions were identified in 4% of patients.   Adverse drug reactions including skin reactions and drug induce hepatitis were noted in 17%. Eighty-two patients achieved complete clinical resolution at the end of 6 months while others were found to have residual lymph nodes necessitating further evaluation. Conclusions: The incidence of TBLN was high among females and in the third decade of life, predominantly affecting cervical lymph nodes. The majority were treated based on primary and ancillary diagnostic test results. Prospective   studies are recommended for more descriptive assessment.
背景:结核性淋巴结炎(TBLN)是斯里兰卡最常见的肺外结核。由于难以获得微生物学确认以及治疗期间缓慢或矛盾的临床反应,TBLN的管理面临许多挑战。目的:描述TBLN患者的人口学特征及与临床表现、诊断方式和治疗结果相关的特征。方法:对科伦坡中央胸科门诊收治的因结核病引起的周围淋巴结肿大患者的临床记录进行审核。结果:对126例临床记录进行分析。男女比例为1:6 .6,平均年龄36岁(SD=17.6)。最常见的部位是颈部淋巴结(94%)。Mantoux试验阳性(>10mm)者占87.5%。122例(97%)患者在初步调查中发现肉芽肿性炎症的证据。其中只有12例(9.5%)微生物学证实,其中5例培养阳性。其余患者(90.5%)通过支持性主要和辅助诊断检查进行诊断。在4%的患者中发现了矛盾反应。17%出现药物不良反应,包括皮肤反应和药物诱发性肝炎。82例患者在6个月结束时达到完全的临床消退,而其他患者发现有残余淋巴结,需要进一步评估。结论:TBLN在女性和30岁年龄段的发病率较高,主要累及颈部淋巴结。大多数患者根据主要和辅助诊断试验结果进行治疗。建议进行前瞻性研究,以进行更具描述性的评估。
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引用次数: 0
Role of lumbar disc degeneration and genetic variation in chronic low back pain 腰椎间盘退变和遗传变异在慢性腰痛中的作用
Pub Date : 2018-08-30 DOI: 10.4038/CJMS.V55I1.4931
R. S. Perera
Low back pain (LBP) is a common symptom and leading cause of disability worldwide. The majority of LBP is due to mechanical causes. However, it is challenging to accurately identify a causative factor for chronic LBP and it is considered a multifactorial condition. Lumbar disc degeneration (LDD) is frequently seen in patients with chronic LBP, but radiological features of disc degeneration is poorly correlated with the symptoms of LBP. The role of radiological investigations in chronic LBP is controversial, but it is frequently used in primary care despite the recommendation to use it only on selected patients with serious underlying pathology or progressive neurological symptoms. Pathophysiology of LDD is complex and is mainly genetically determined. Genetic variation may help in classifying varying degrees of LBP in patients with LDD. Improved understanding of the role of radiological features in LDD and genetic investigations help in advancing personalized care and implementing innovative strategies in the management of chronic LBP.
腰痛(LBP)是世界范围内常见的症状和致残的主要原因。大多数腰痛是由机械原因引起的。然而,准确地确定慢性腰痛的致病因素是具有挑战性的,它被认为是一个多因素的条件。腰椎间盘退变(LDD)常见于慢性腰痛患者,但腰椎间盘退变的影像学特征与腰痛症状相关性较差。放射学检查在慢性腰痛中的作用是有争议的,但它经常用于初级保健,尽管推荐仅用于具有严重潜在病理或进行性神经症状的特定患者。LDD的病理生理是复杂的,主要是由基因决定的。遗传变异有助于对LDD患者不同程度的腰痛进行分类。提高对LDD的放射学特征和遗传调查的作用的理解有助于推进个性化护理和实施慢性LBP管理的创新策略。
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引用次数: 0
Can the arts promote more humane health professionals? Exploring evidence from the neurosciences 艺术能促进更人性化的卫生专业人员吗?探索神经科学的证据
Pub Date : 2018-08-30 DOI: 10.4038/CJMS.V55I1.4938
S. Jayasinghe
The Sri Lankan health profession is in urgent need of being more humane, compassionate and empathic. This requires education to widen its scope than medical ethics and communication skills. Medical Humanities is one such interdisciplinary fields that draws on the creative and intellectual strengths of diverse disciplines related to the humanities, including, but not limited to philosophy, ethics, literature, art, creative writing, drama, film, music, anthropology, and history. The challenge is the use of these diverse fields in a creative manner to achieve the goal of developing more humane health professionals.
斯里兰卡的卫生专业人员迫切需要更加人道、富有同情心和同理心。这需要扩大教育的范围,而不是医学伦理和沟通技巧。医学人文学科就是这样一个跨学科领域,它利用了与人文学科相关的各种学科的创造性和智力优势,包括但不限于哲学、伦理学、文学、艺术、创意写作、戏剧、电影、音乐、人类学和历史。挑战在于以创造性的方式利用这些不同的领域,以实现培养更人性化的卫生专业人员的目标。
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引用次数: 1
Does inhibitory dysfunction contribute to poor emotional aspect of eating behaviours in obesity? A study among a sample of young adults in Colombo District, Sri Lanka. 抑制性功能障碍是否会导致肥胖患者饮食行为的情绪不佳?斯里兰卡科伦坡地区年轻人样本研究。
Pub Date : 2018-08-30 DOI: 10.4038/CJMS.V55I1.4911
Nimantha Karunathilaka, Chandana Hewage, S. Wimalasekera, T. Amarasekara
Background: Recent studies have suggested that poor inhibitory control can lead to poor emotional aspect of eating behaviour resulting in obesity. Considering this, a study was conducted to assess the association between obesity, inhibitory control and emotional aspect of eating behaviour among young adults in Colombo District, Sri Lanka. Methods: Young adults of age 21–25 years (n=231) were studied. Body Mass Index (BMI) and Waist to Hip Ratio (WHR) were calculated to assess the generalized and central obesity, while inhibitory control was assessed through number of incorrect responses in Stroop, Stop signal and Go/no-go tasks. The emotional aspect of eating behaviour was assessed via self-administered Three Factor Eating Questionnaire (Revised-18), which consists of three subscales; cognitive restraint, uncontrolled eating and emotional eating. Results: The mean age of the study sample was 23.4±1.4 years with males comprising 51.9%. There was a statistically significant group effect in mean incorrect responses of Stroop task and Stop signal task scores with normal, overweight and obese individuals (p 0.05). A positive significant correlation was observed in mean incorrect responses of Stroop task with cognitive restraint subscale (r=0.238, p Conclusion: Poor inhibitory control with abnormal emotional aspect of eating despite cognitive restraint was seen in those with obesity.
背景:最近的研究表明,不良的抑制控制会导致饮食行为的情感方面的不良,从而导致肥胖。考虑到这一点,在斯里兰卡科伦坡地区的年轻人中进行了一项研究,以评估肥胖、抑制控制和饮食行为情感方面之间的关系。方法:研究年龄21 ~ 25岁的青壮年(n=231)。计算身体质量指数(BMI)和腰臀比(WHR)来评估全身性和中枢性肥胖,而通过Stroop、停止信号和Go/no-go任务中的错误反应数来评估抑制控制。饮食行为的情绪方面通过自我管理的三因素饮食问卷(修订版-18)进行评估,该问卷由三个分量表组成;认知限制,不受控制的进食和情绪化进食。结果:研究样本平均年龄为23.4±1.4岁,男性占51.9%。正常、超重和肥胖个体Stroop任务和Stop信号任务得分的平均错误反应组效应有统计学意义(p < 0.05)。Stroop任务的平均错误反应与认知约束分量表存在显著正相关(r=0.238, p)。结论:肥胖患者在认知约束的情况下仍存在抑制控制不良和饮食情绪异常。
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引用次数: 0
Epidemiology and clinical presentation of patients with melioidoisis at the District General Hospital, Chilaw 奇劳区总医院类鼻疽患者的流行病学和临床表现
Pub Date : 2018-08-30 DOI: 10.4038/CJMS.V55I1.4925
P. Bandara, R. Fernando, Amali Thennakoon, S. Fernando, E. Corea, J. Masakorala
Background : Melioidosis is emerging in Sri Lanka. Clinical presentation is variable. Underlying risk factors include diabetes. Objective: To describe the epidemiology of patients with culture confirmed melioidosis presenting to the District General Hospital, Chilaw between 2014-2017. Method: Melioidosis was diagnosed in the microbiology laboratory by culture of Burkholderia pseudomallei from patients’ specimens. Isolates were confirmed by polymerase chain reaction (PCR). Antibodies were detected using the Indirect Haemagglutination Assay (IHA). Epidemiological data were collected from patients using a questionnaire. Results: Culture positive melioidosis was found in 15 patients. Melioidosis was more common in males and in adults. Clinical presentation was variable. Diabetes was the most important underlying risk factor. The case fatality rate was 40%. Conclusions: This case series demonstrates that melioidosis is endemic in the North Western Province and is an important cause of community acquired infection.
背景:斯里兰卡正在出现类鼻疽病。临床表现多变。潜在的危险因素包括糖尿病。目的:了解2014-2017年齐罗市区总医院培养确诊类鼻疽患者的流行病学。方法:在微生物实验室对患者标本进行假马利氏伯克氏菌培养,诊断为类鼻疽。分离株经聚合酶链反应(PCR)鉴定。采用间接血凝试验(IHA)检测抗体。通过问卷调查收集患者的流行病学数据。结果:15例患者类鼻疽培养阳性。类鼻疽多见于男性和成人。临床表现多变。糖尿病是最重要的潜在危险因素。病死率为40%。结论:本病例系列表明,类鼻疽病在西北省流行,是社区获得性感染的重要原因。
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引用次数: 0
Left main coronary artery aneurism in an adult 成人左主干冠状动脉动脉瘤
Pub Date : 2018-08-30 DOI: 10.4038/CJMS.V55I1.4934
Lakshman Bandara, T. Kogulan, A. Jegavanthan, G. Weerakoon
A 46-year old lady with essential hypertension presented with recurrent episodes of Non-ST-elevation myocardial infarctions over a period of six months. Each episode was associated with classical chest pain, dynamic electrocardiographic changes and elevated cardiac enzymes. Two dimensional echocardiography showed evidence of hypertensive heart disease and dilated left main coronary artery with turbulent flow (Figure A). Trans-oesophageal echocardiography demonstrated the dilated segment clearly and 3 dimensional navigation showed more details of the abnormal segment (Figure B). The conventional coronary angiography, further elaborated the aneurismal segment, with turbulence and stagnation of the dye reflecting the indirect evidence of hemodynamic states of the aneurismal segment (Figure C). Except the left main, all other coronary arteries were normal. Finally, she was subjected to computer tomographic coronary angiography which showed excellent details of the aneurism in relation to origin, extension and the anatomy of the bifurcation, the essential details required for the surgeons (Figure D). Since the patient had a nidus for in-situ thrombi formation, which is the most likely cause for recurrent myocardial infarctions the decision to close the defect by surgery was taken. She was planned for aneurismal ligation with re-establishment of flow by coronary artery bypass grafting. The case illustrates the use of different modalities of coronary imaging in complex situations to obtain an accurate therapeutic decision.
一位46岁的原发性高血压女性在6个月的时间里出现了反复发作的非st段抬高型心肌梗死。每次发作均伴有典型胸痛、动态心电图改变和心酶升高。二维超声心动图显示高血压心脏病,左冠状动脉主动脉扩张伴湍流(图A)。经食管超声心动图清晰显示扩张段,三维导航显示异常段更详细(图B)。常规冠状动脉造影进一步阐述了动脉瘤段。染料的湍流和停滞反映了动脉瘤段血流动力学状态的间接证据(图C)。除左主干外,其他冠状动脉均正常。最后,她接受了计算机断层冠状动脉造影,显示了动脉瘤的起源、延伸和分叉解剖的详细信息,这是外科医生需要的基本细节(图D)。由于患者有一个原位血栓形成的病灶,这是最可能导致复发性心肌梗死的原因,因此决定通过手术关闭缺陷。她计划通过冠状动脉旁路移植术结扎动脉瘤并重新建立血流。该病例说明了在复杂情况下使用不同方式的冠状动脉成像以获得准确的治疗决定。
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引用次数: 0
Service quality of school canteens: a case study from the Western Province, Sri Lanka 学校食堂服务质量:以斯里兰卡西部省为例
Pub Date : 2017-12-27 DOI: 10.4038/CJMS.V54I2.4817
M. Weerasinghe, S. Bandara, M. Sanoon
Background: Creating a healthy eating environment in schools is a proposed outcome of school canteen guidelines issued in 2007 in Sri Lanka. Maintaining service quality, guarantees achieving better health standards of school canteens. Objectives: This study assessed service quality of canteens in terms of location, physical facilities in food preparation and serving areas, food handling practices, food storage, and waste management. Further, it explored causes for deviating the service quality from the stipulated guidelines. Methods: This is a across sectional study, conducted in government schools in two districts in 2014. Service qualities of the canteens were assessed using a quantitative tool. Qualitative inquiry was used to explore perceptions of school principals and canteen operators on service quality. Results: Eighty eight percent of canteens were located in a suitable place and 78% had a clean outside environment. Only two third of food preparation areas satisfied the basic criteria. A dining area was available for students only in half. More than 80% of canteens had waste water drainage and 89% of canteens had bins for waste disposal. However, majority of canteens did not keep bins closed. Half of the canteens had cooling equipment, and majority of them had a practice to store raw materials and cooked food separately. Almost in 30 % of canteens, food was not covered in the serving area, and more than 90% of canteens used neither aprons nor gloves. Conclusion: This study found that providing quality food quality in school canteens has been a challenge due to many gaps in the present system. However, strengthening the service quality towards a healthy nutrition promoting setting can be done by change in planning and implementation processes.
背景:在学校创造健康的饮食环境是斯里兰卡2007年发布的学校食堂指导方针的一项拟议成果。保持服务质量,保证学校食堂达到更好的卫生标准。目的:本研究评估了食堂的服务质量,包括地点、食物准备和服务区域的物理设施、食物处理方式、食物储存和废物管理。进一步探讨了服务质量偏离规定准则的原因。方法:这是一项横断面研究,于2014年在两个地区的公立学校进行。使用定量工具评估食堂的服务质量。本研究采用质性调查探讨学校校长及食堂经营者对服务质素的看法。结果:88%的食堂选址适宜,78%的食堂室外环境干净。只有三分之二的食品准备区域符合基本标准。只有一半的学生可以用餐。超过80%的食堂有污水排放系统,89%的食堂有垃圾垃圾箱。然而,大多数食堂并没有关闭垃圾箱。一半的食堂有冷却设备,大多数食堂有将原材料和熟食分开存放的做法。近30%的食堂在服务区域没有覆盖食物,超过90%的食堂既不使用围裙也不使用手套。结论:本研究发现,由于现有系统存在许多差距,在学校食堂提供优质食品质量一直是一项挑战。然而,可以通过改变规划和执行过程来加强服务质量,以促进健康营养的环境。
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引用次数: 6
Associated factors of electrical injuries and knowledge on their prevention and first aid management among Ceylon Electricity Board (CEB) field level technical workers in Colombo municipal area 科伦坡市辖区锡兰电力委员会现场技术工人的电气伤害相关因素及其预防和急救管理知识
Pub Date : 2017-12-27 DOI: 10.4038/CJMS.V54I2.4804
K. Arachchi, P. G. K. M. Kumarawansha, K. Kuruppu, Laboshan Kaliyugavarathan, D. Samaranayake
Background Electrical injuries carry a high risk of morbidity and mortality. Electrical workers are at a constant risk of such injuries. Accurate knowledge on prevention and first aid and putting it into practice is important for preventing and reducing these injuries. Objectives This study aimed to assess the associated factors of incidence of workplace electrical injuries and knowledge on prevention and first aid management among Ceylon Electricity Board (CEB) field level technical workers of the Colombo Municipal area. Methods This is a descriptive cross-sectional study conducted among 120 field level technical workers selected through two-stage cluster sampling. An interviewer-administered questionnaire was employed to gather information. Data was analyzed using descriptive statistics and Chi-square test. Results The sample consisted of only males, with a mean age of 37.19 years (SD=11.08). Self-reported injury incidence among the workers was 6% per year and no significant association was seen between injury incidence and any of the socio-demographic or work-related characteristics. Majority had a good knowledge on prevention (75.8%) and first aid management (81.7%). Having a total number of 1 to 3 training sessions on prevention during the time of occupation showed a significant association with knowledge on prevention (p=0.006) and occupational grade showed a significant association with knowledge on first aid management (p=0.013). Conclusions The knowledge on prevention and first aid for electrical burn injuries was satisfactory. Occupational grade and the number of training programmes attended influenced their level of knowledge.
背景:电损伤具有很高的发病率和死亡率。电气工人经常面临这种伤害的危险。准确了解预防和急救知识并付诸实践对于预防和减少这些伤害非常重要。目的本研究旨在评估工作场所电气伤害发生率的相关因素以及科伦坡市辖区锡兰电力委员会(CEB)现场技术工人的预防和急救管理知识。方法采用两阶段整群抽样的方法,对120名现场技术工人进行描述性横断面研究。采用访谈者填写的问卷收集信息。数据分析采用描述性统计和卡方检验。结果本组全部为男性,平均年龄37.19岁(SD=11.08)。工人自我报告的伤害发生率为每年6%,伤害发生率与任何社会人口统计学或工作相关特征之间没有显着关联。大多数人对预防(75.8%)和急救管理(81.7%)有良好的了解。职业期间共接受过1 - 3次预防培训与预防知识显著相关(p=0.006),职业等级与急救管理知识显著相关(p=0.013)。结论对电烧伤的预防和急救知识了解较好。职业等级和参加培训课程的次数影响了他们的知识水平。
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引用次数: 1
A vanishing callosal lesion on brain imaging in a patient with meningoencephalitis 脑膜脑炎患者脑成像上胼胝体病变消失
Pub Date : 2017-12-27 DOI: 10.4038/CJMS.V54I2.4910
Thashi Chang, R. Karunarathne, C. D. Mel
A 21-year-old previously healthy man had become progressively unresponsive five days after developing highgrade fever. On examination, he was unconscious (GCS 3/15), with equally reacting normal-sized pupils and normal optic fundi, and marked neck stiffness. His blood investigations showed neutrophil leucocytosis (total white cells 21,250/μl; 88% neutrophils) and serum sodium of 112 mmol/l. Magnetic resonance imaging of the brain was normal except for a non-enhancing focal hyperintensity on T2 and FLAIR sequences with diffusion restriction and low signal on ADC map in the splenium of the corpus callosum (Figure). Cerebrospinal fluid analysis showed polymorphocytic pleocytosis (225 cells/μl; 80% polymorphocytes), elevated protein (99 mg/dl) and a CSF: plasma glucose ratio of 0.28. A diagnosis of pyogenic meningoencephalitis was established. The patient made a complete recovery after a 14-day course of intravenous meropenem and vancomycin. MRI repeated 14 days after completion of antibiotics showed complete resolution of the splenial hyperintensity.
一名21岁的健康男子在出现高热5天后逐渐失去反应。检查时,患者失去知觉(GCS 3/15),瞳孔大小正常,视底正常,颈部明显僵硬。血液检查显示中性粒细胞白细胞增多(白细胞总数21,250/μl;88%中性粒细胞),血清钠112 mmol/l。脑磁共振示胼胝体脾部除T2和FLAIR无增强局灶性高信号、扩散受限、ADC低信号外,其余正常(图)。脑脊液分析显示多形细胞增多症(225个细胞/μl;80%多形细胞),蛋白升高(99 mg/dl),脑脊液:血浆葡萄糖比值0.28。诊断为化脓性脑膜脑炎。患者经14天静脉注射美罗培南和万古霉素后完全康复。停用抗生素14天后复查MRI显示脾脏高强度完全消失。
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引用次数: 0
The level of happiness among garment factory employees and factors affecting it, in two selected garment factories. 在两个选定的服装厂中,服装厂员工的幸福水平及其影响因素。
Pub Date : 2017-12-27 DOI: 10.4038/CJMS.V54I2.4809
L. Kodithuwakku, C. Kodithuwakku, S. Kirushanth, W. Khandu, Thashi Chang
Background Happiness is a key factor in health and recently it has become the goal in most human organizations as productivity improves with improved happiness. Objective To assess the level of happiness and factors affecting it among the workers in two selected garment factories in the districts of Colombo and Gampaha. Methods A descriptive cross–sectional study was conducted among 127 workers in two garment factories situated in Colombo and Gampaha. A self-administered questionnaire was used to gather information on the demographic characteristics, job satisfaction, level of happiness and other selected variables. The data was analyzed using descriptive statistics and Chi-square test. Results Sixty three percent of the study population were in the highest category of the level of happiness indicated as “very happy”. Among the factors assessed to affect happiness; positive associations were found with friendly working environment (p=0.02), job satisfaction (p=0.03) and current marital status (p=0.01); while no associations were found for salary grade and number of job accidents. Conclusions There is satisfactory levels of happiness among garment factory workers in the selected study group. There is opportunity for further improvement in the level of happiness through manipulation of friendly working environment, job satisfaction and current marital status due to their positive correlation with the level of happiness.
幸福是健康的一个关键因素,最近它已经成为大多数人类组织的目标,因为生产力随着幸福程度的提高而提高。目的了解科伦坡和甘帕哈地区两家制衣厂工人的幸福水平及其影响因素。方法对位于科伦坡和甘巴哈的两家服装厂的127名工人进行描述性横断面研究。一份自我管理的问卷用于收集人口统计特征、工作满意度、幸福水平和其他选定变量的信息。采用描述性统计和卡方检验对资料进行分析。结果63%的研究对象处于“非常幸福”这一幸福水平的最高类别。在被评估影响幸福感的因素中;友善的工作环境(p=0.02)、工作满意度(p=0.03)和当前婚姻状况(p=0.01)正相关;而工资等级和工伤事故数量没有关联。结论在所选研究组中,服装厂工人的幸福水平令人满意。由于友好的工作环境、工作满意度和当前婚姻状况与幸福感水平正相关,因此有机会进一步提高幸福感水平。
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引用次数: 1
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Ceylon Journal of Medical Science
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