首页 > 最新文献

2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)最新文献

英文 中文
WeedGait: Unobtrusive Smartphone Sensing of Marijuana-Induced Gait impairment By Fusing Gait Cycle Segmentation and Neural Networks 杂草步态:融合步态周期分割和神经网络的智能手机感应大麻诱导的步态损伤
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962787
Ruojun Li, E. Agu, G. Balakrishnan, D. Herman, Ana M. Abrantes, Michael Stein, Jane Metrik
The use of marijuana is now legal for medical purposes in 39 of the 50 United States. Eleven of these 39 states have also legalized marijuana for non-medical usage. Marijuana impairs the motor skills of users, making Driving Under the Influence of Marijuana (DUIM) a growing public health concern. There are currently few accessible and accurate methods to assess the impairment levels of drivers who have used marijuana. Current assessment methods include self-reports and testing urine, oral fluid, and blood. However, self-reports are often biased and biological tests are cumbersome to perform in situ. In this paper, we investigate whether dose-dependent changes in participants gait (walk) can be detected using data gathered from their smartphone motion sensors (accelerometer and gyroscope). We envision WeedGait, a smartphone sensing system that will assess the gait of marijuana users passively and warn them when they are too impaired to drive safely. To the best of our knowledge, this is the first study on using smartphones to assess marijuana-induced gait impairment. Gait data was collected from 10 subjects and pre-processing steps included low pass filtering, step cycle detection and segmentation, and normalization. We present a novel gait analysis approach that analyzes normalized, single-step segments to achieve higher accuracy than prior approaches. We compared the classification results of various machine and deep learning models, and found that Long Short Time Memory (LSTM) and Support Vector Machines performed best, discriminating the gait of subjects after smoking either marijuana with 3% or 7.2% THC versus smoking a placebo marijuana cigarette with an accuracy of 92.1%. These results suggest that smartphone-based marijuana testing is more accurate than urine-based tests but slightly less accurate than oral fluid based testing. Moreover, smartphone sensing of marijuana is completely passive and hence more convenient, which facilitates pervasive testing in natural settings and could have massive impact due to the near-ubiquity of smartphones.
目前,美国50个州中有39个州将大麻用于医疗目的合法化。这39个州中有11个州也将非医疗用途的大麻合法化。大麻会损害使用者的运动技能,使大麻影响下驾驶(DUIM)成为一个日益严重的公共健康问题。目前,几乎没有可行且准确的方法来评估使用大麻的司机的损伤程度。目前的评估方法包括自我报告和检测尿液、口服液和血液。然而,自我报告往往是有偏见的,生物测试在现场进行是繁琐的。在本文中,我们研究了是否可以使用从智能手机运动传感器(加速度计和陀螺仪)收集的数据来检测参与者步态(步行)的剂量依赖性变化。我们设想一种名为WeedGait的智能手机传感系统,它可以被动地评估大麻使用者的步态,并在他们严重受损而无法安全驾驶时发出警告。据我们所知,这是第一个使用智能手机来评估大麻引起的步态障碍的研究。采集了10名受试者的步态数据,预处理步骤包括低通滤波、步进周期检测和分割、归一化。我们提出了一种新的步态分析方法,该方法分析归一化的单步片段,以达到比先前方法更高的精度。我们比较了各种机器和深度学习模型的分类结果,发现长短时记忆(LSTM)和支持向量机(Support Vector Machines)表现最好,在吸食3%或7.2%四氢大麻酚的大麻与吸食安慰剂的大麻香烟后区分受试者的步态,准确率为92.1%。这些结果表明,基于智能手机的大麻检测比基于尿液的检测更准确,但略低于基于口服液的检测。此外,智能手机对大麻的感知是完全被动的,因此更方便,这有利于在自然环境中进行普遍的测试,并且由于智能手机几乎无处不在,可能会产生巨大的影响。
{"title":"WeedGait: Unobtrusive Smartphone Sensing of Marijuana-Induced Gait impairment By Fusing Gait Cycle Segmentation and Neural Networks","authors":"Ruojun Li, E. Agu, G. Balakrishnan, D. Herman, Ana M. Abrantes, Michael Stein, Jane Metrik","doi":"10.1109/HI-POCT45284.2019.8962787","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962787","url":null,"abstract":"The use of marijuana is now legal for medical purposes in 39 of the 50 United States. Eleven of these 39 states have also legalized marijuana for non-medical usage. Marijuana impairs the motor skills of users, making Driving Under the Influence of Marijuana (DUIM) a growing public health concern. There are currently few accessible and accurate methods to assess the impairment levels of drivers who have used marijuana. Current assessment methods include self-reports and testing urine, oral fluid, and blood. However, self-reports are often biased and biological tests are cumbersome to perform in situ. In this paper, we investigate whether dose-dependent changes in participants gait (walk) can be detected using data gathered from their smartphone motion sensors (accelerometer and gyroscope). We envision WeedGait, a smartphone sensing system that will assess the gait of marijuana users passively and warn them when they are too impaired to drive safely. To the best of our knowledge, this is the first study on using smartphones to assess marijuana-induced gait impairment. Gait data was collected from 10 subjects and pre-processing steps included low pass filtering, step cycle detection and segmentation, and normalization. We present a novel gait analysis approach that analyzes normalized, single-step segments to achieve higher accuracy than prior approaches. We compared the classification results of various machine and deep learning models, and found that Long Short Time Memory (LSTM) and Support Vector Machines performed best, discriminating the gait of subjects after smoking either marijuana with 3% or 7.2% THC versus smoking a placebo marijuana cigarette with an accuracy of 92.1%. These results suggest that smartphone-based marijuana testing is more accurate than urine-based tests but slightly less accurate than oral fluid based testing. Moreover, smartphone sensing of marijuana is completely passive and hence more convenient, which facilitates pervasive testing in natural settings and could have massive impact due to the near-ubiquity of smartphones.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128639399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Facial Expression-Based Emotion Classification using Electrocardiogram and Respiration Signals 基于面部表情的心电图和呼吸信号情绪分类
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962891
D. S. Wickramasuriya, Mikayla K. Tessmer, R. Faghih
Automated emotion recognition from physiological signals is an ongoing research area. Many studies rely on self-reported emotion scores from subjects to generate classification labels. This can introduce labeling inconsistencies due to inter-subject variability. Facial expressions provide a more consistent means of generating labels. We generate labels by selecting locations at which subjects either displayed a visibly averse/negative reaction or laughed in video recordings. We next use a supervised learning approach for classifying these emotional responses based on electrocardiogram (EKG) and respiration signal features in an experiment where different movie/video clips were utilized to elicit feelings of joy, disgust, amusement, etc. As features, we extract wavelet coefficient patches from EKG RR-interval time series and respiration waveform parameters. We use principal component analysis for dimensionality reduction and support vector machines for classification. We achieved an overall classification accuracy of 78.3%.
从生理信号中自动识别情绪是一个正在进行的研究领域。许多研究依赖于受试者自我报告的情绪得分来生成分类标签。这可能会由于主体间的可变性而导致标签不一致。面部表情提供了一种更一致的生成标签的方式。我们通过选择被试在录像中表现出明显厌恶/消极反应或大笑的地点来生成标签。接下来,我们使用一种监督学习方法,根据心电图(EKG)和呼吸信号特征对这些情绪反应进行分类,在一个实验中,不同的电影/视频片段被用来引发喜悦、厌恶、娱乐等感觉。作为特征,我们从心电图rr间隔时间序列和呼吸波形参数中提取小波系数补丁。我们使用主成分分析进行降维,使用支持向量机进行分类。我们实现了78.3%的总体分类准确率。
{"title":"Facial Expression-Based Emotion Classification using Electrocardiogram and Respiration Signals","authors":"D. S. Wickramasuriya, Mikayla K. Tessmer, R. Faghih","doi":"10.1109/HI-POCT45284.2019.8962891","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962891","url":null,"abstract":"Automated emotion recognition from physiological signals is an ongoing research area. Many studies rely on self-reported emotion scores from subjects to generate classification labels. This can introduce labeling inconsistencies due to inter-subject variability. Facial expressions provide a more consistent means of generating labels. We generate labels by selecting locations at which subjects either displayed a visibly averse/negative reaction or laughed in video recordings. We next use a supervised learning approach for classifying these emotional responses based on electrocardiogram (EKG) and respiration signal features in an experiment where different movie/video clips were utilized to elicit feelings of joy, disgust, amusement, etc. As features, we extract wavelet coefficient patches from EKG RR-interval time series and respiration waveform parameters. We use principal component analysis for dimensionality reduction and support vector machines for classification. We achieved an overall classification accuracy of 78.3%.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123114624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Machine learning algorithm to predict coronary artery calcification in asymptomatic healthy population 预测无症状健康人群冠状动脉钙化的机器学习算法
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962647
K. Kolli, S. H. Park, J. Min, H. Chang, D. Han, H. Gransar, J. Lee, Su-Yeon Choi, E. Chun, H. Jung, J. Sung, H. Han
Coronary artery calcium (CAC) is an established surrogate marker for coronary atherosclerotic disease (CAD) burden. The CAC score is also an independent predictor of adverse events with significant incremental prognostic value over traditional/clinical risk stratification algorithms. The objective of this study was to examine the prognostic ability of Machine learning (ML) based algorithms to predict multi-class CAC (0: normal; 1–100: low risk CAD; 101–400 Intermediate risk CAD; >400 severe/high risk CAD) from available electronic health record (EHR) data. A retrospective observation study of 60,923 asymptomatic patients with clinically evaluated CAC score along with sixty five clinical and laboratory parameters were included in developing the ML algorithm (data split into 70% [training] and 30% [test]). In addition, a separate cohort of 7,552 patients was used to externally validate the developed ML algorithm. Classification performance was assessed using the area under the receiver operating curve (AUC). The prediction algorithm derived from the ML method showed high predictive value for CAC risk category.
冠状动脉钙(CAC)是冠状动脉粥样硬化疾病(CAD)负担的替代标志物。CAC评分也是不良事件的独立预测因子,与传统/临床风险分层算法相比,其预后价值显著增加。本研究的目的是检验基于机器学习(ML)的算法预测多类CAC的预测能力(0:正常;1-100:低风险CAD;101-400中危CAD;>400严重/高风险CAD),来自现有电子健康记录(EHR)数据。一项回顾性观察研究纳入了60,923名无症状患者的临床评估CAC评分以及65个临床和实验室参数,以开发ML算法(数据分为70%[训练]和30%[测试])。此外,一个独立的7552例患者队列被用于外部验证开发的ML算法。采用受试者工作曲线下面积(AUC)评价分类效果。基于ML方法的预测算法对CAC风险类别具有较高的预测价值。
{"title":"Machine learning algorithm to predict coronary artery calcification in asymptomatic healthy population","authors":"K. Kolli, S. H. Park, J. Min, H. Chang, D. Han, H. Gransar, J. Lee, Su-Yeon Choi, E. Chun, H. Jung, J. Sung, H. Han","doi":"10.1109/HI-POCT45284.2019.8962647","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962647","url":null,"abstract":"Coronary artery calcium (CAC) is an established surrogate marker for coronary atherosclerotic disease (CAD) burden. The CAC score is also an independent predictor of adverse events with significant incremental prognostic value over traditional/clinical risk stratification algorithms. The objective of this study was to examine the prognostic ability of Machine learning (ML) based algorithms to predict multi-class CAC (0: normal; 1–100: low risk CAD; 101–400 Intermediate risk CAD; >400 severe/high risk CAD) from available electronic health record (EHR) data. A retrospective observation study of 60,923 asymptomatic patients with clinically evaluated CAC score along with sixty five clinical and laboratory parameters were included in developing the ML algorithm (data split into 70% [training] and 30% [test]). In addition, a separate cohort of 7,552 patients was used to externally validate the developed ML algorithm. Classification performance was assessed using the area under the receiver operating curve (AUC). The prediction algorithm derived from the ML method showed high predictive value for CAC risk category.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132783203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Deep Metric Learning with Triplet Networks: Application to Hand-grip Myotonia Quantification 深度度量学习与三重网络:应用于手部肌强直量化
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962888
Lei Lin, Beilei Xu, Wencheng Wu, Trevor W. Richardson, Edgar A. Bernal, Bill Martens, C. Thornton, C. Heatwole
Myotonia, which refers to delayed muscle relaxation after contraction, is the main symptom of myotonic dystrophy patients. The relaxation time after a hand squeeze has been used as a biomarker for diagnostic purposes and in clinical trials to quantify the effectiveness of a treatment. Current processes that rely on handcrafted features tend to be sensitive to data acquisition noise and intra- and inter-patient variability. In this work, we develop a deep metric learning framework for analyzing the hand-grip time series based on triplet-networks. Experiments show that the learned embedding space can be used to quantify the symptoms, evaluate the effectiveness of treatments, and design new data collection protocols.
肌强直是指收缩后肌肉松弛延迟,是肌强直营养不良患者的主要症状。握紧手后的放松时间已被用作诊断目的的生物标志物,并在临床试验中用于量化治疗效果。目前依赖于手工特征的过程往往对数据采集噪声和患者内部和患者之间的可变性很敏感。在这项工作中,我们开发了一个基于三重网络的深度度量学习框架,用于分析手部握力时间序列。实验表明,学习嵌入空间可用于量化症状、评估治疗效果和设计新的数据收集方案。
{"title":"Deep Metric Learning with Triplet Networks: Application to Hand-grip Myotonia Quantification","authors":"Lei Lin, Beilei Xu, Wencheng Wu, Trevor W. Richardson, Edgar A. Bernal, Bill Martens, C. Thornton, C. Heatwole","doi":"10.1109/HI-POCT45284.2019.8962888","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962888","url":null,"abstract":"Myotonia, which refers to delayed muscle relaxation after contraction, is the main symptom of myotonic dystrophy patients. The relaxation time after a hand squeeze has been used as a biomarker for diagnostic purposes and in clinical trials to quantify the effectiveness of a treatment. Current processes that rely on handcrafted features tend to be sensitive to data acquisition noise and intra- and inter-patient variability. In this work, we develop a deep metric learning framework for analyzing the hand-grip time series based on triplet-networks. Experiments show that the learned embedding space can be used to quantify the symptoms, evaluate the effectiveness of treatments, and design new data collection protocols.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128727486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
HI-POCT 2019 EMBS Information HI-POCT 2019 EMBS信息
Pub Date : 2019-11-01 DOI: 10.1109/hi-poct45284.2019.8962894
{"title":"HI-POCT 2019 EMBS Information","authors":"","doi":"10.1109/hi-poct45284.2019.8962894","DOIUrl":"https://doi.org/10.1109/hi-poct45284.2019.8962894","url":null,"abstract":"","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125421689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic Phagocyte Quantification Framework for Point-of-Care Diagnostics 用于即时诊断的磁性吞噬细胞定量框架
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962692
Corey Norton, Kurt Wagner, U. Hassan
A novel framework to quantify the phagocytic ability of a septic patient’s immune system is proposed for Point-of-Care (PoC) diagnostic applications. The design utilizes biofunctionalized ferromagnetic particles to affect the flow rate of phagocytes passing through an impedimetric sensor. The electrical, microfluidic, and magnetic subsystems of the design are analyzed. Preliminary simulation and experimental results demonstrate the feasibility of the system. Additionally, fabrication procedures and system calibrations are discussed, and a control assay is proposed.
提出了一种新的框架来量化败血症患者免疫系统的吞噬能力,用于即时诊断(PoC)应用。该设计利用生物功能化的铁磁颗粒来影响通过阻抗传感器的吞噬细胞的流速。对设计的电气、微流控和磁子系统进行了分析。初步的仿真和实验结果验证了该系统的可行性。此外,还讨论了制造过程和系统校准,并提出了一种控制分析方法。
{"title":"Magnetic Phagocyte Quantification Framework for Point-of-Care Diagnostics","authors":"Corey Norton, Kurt Wagner, U. Hassan","doi":"10.1109/HI-POCT45284.2019.8962692","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962692","url":null,"abstract":"A novel framework to quantify the phagocytic ability of a septic patient’s immune system is proposed for Point-of-Care (PoC) diagnostic applications. The design utilizes biofunctionalized ferromagnetic particles to affect the flow rate of phagocytes passing through an impedimetric sensor. The electrical, microfluidic, and magnetic subsystems of the design are analyzed. Preliminary simulation and experimental results demonstrate the feasibility of the system. Additionally, fabrication procedures and system calibrations are discussed, and a control assay is proposed.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133680244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Conjugated Barcoded Particles for Multiplexed Biomarker Quantification with a Microfluidic Biochip 用微流控生物芯片进行多路生物标志物定量的共轭条形码颗粒
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962846
Shreya Prakash, Maxwell B. Nagarajan, P. Doyle, R. Bashir, U. Hassan
Multiplexing is a method of analyzing multiple analytes in a biological assay in a single step. Multiplexing provides advantages of sample sparring, shorter time to result and reduce tests cost. To achieve multiplexing we have used barcoded particles which were fabricated by a Stop Flow Lithography process in a microfluidic environment. Here, we present a microfluidic system for electrical differentiation of barcoded particles and its sensitivity to enumerate blood cells. The barcoded particles conjugated with different sized microspheres simulating blood cells generated distinct electrical signatures when passed through a microfluidic coulter counter, highlighting its ability for multiplexed analyte quantification. Such multiplexing system can be used for detecting multiple diagnostics and prognostic biomarkers in diseases like Sepsis, Acute Kidney Injury, and AIDS diagnostic and management.
多路复用是在单个步骤中分析生物测定中的多个分析物的方法。多路复用具有节省样品、缩短测试时间和降低测试成本的优点。为了实现多路复用,我们使用了在微流体环境中通过停止流光刻工艺制造的条形码颗粒。在这里,我们提出了一种用于条形码颗粒电分化的微流体系统及其枚举血细胞的敏感性。与不同大小的模拟血细胞的微球结合的条形码颗粒在通过微流控coulter计数器时产生了不同的电特征,突出了其多路分析物定量的能力。该多路复用系统可用于脓毒症、急性肾损伤、艾滋病等疾病的诊断和管理中多种诊断和预后生物标志物的检测。
{"title":"Conjugated Barcoded Particles for Multiplexed Biomarker Quantification with a Microfluidic Biochip","authors":"Shreya Prakash, Maxwell B. Nagarajan, P. Doyle, R. Bashir, U. Hassan","doi":"10.1109/HI-POCT45284.2019.8962846","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962846","url":null,"abstract":"Multiplexing is a method of analyzing multiple analytes in a biological assay in a single step. Multiplexing provides advantages of sample sparring, shorter time to result and reduce tests cost. To achieve multiplexing we have used barcoded particles which were fabricated by a Stop Flow Lithography process in a microfluidic environment. Here, we present a microfluidic system for electrical differentiation of barcoded particles and its sensitivity to enumerate blood cells. The barcoded particles conjugated with different sized microspheres simulating blood cells generated distinct electrical signatures when passed through a microfluidic coulter counter, highlighting its ability for multiplexed analyte quantification. Such multiplexing system can be used for detecting multiple diagnostics and prognostic biomarkers in diseases like Sepsis, Acute Kidney Injury, and AIDS diagnostic and management.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116106705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays 横向流动免疫分析中相对湿度、温度和几何形状对流体流速的影响
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962702
Nipun Thamatam, J. Christen
Lateral Flow Immunoassays (LFIAs) are among the most successful Point of Care (POC) tests. However, factors like reagent stability, reaction rates, and binding kinetics limit the performance and robustness of LFIAs. One of the factors that affects the overall performance of LFIA is the fluid flow rate, and hence, it is desirable to maintain a predictable fluid velocity in porous media. The main objective of this study is to build a statistical model that estimates the fluid velocity in porous media for any given ambient condition to enable us to determine the optimal design parameters for achieving a desired fluid velocity in porous media.
侧流免疫测定(LFIAs)是最成功的护理点(POC)测试之一。然而,试剂稳定性、反应速率和结合动力学等因素限制了LFIAs的性能和鲁棒性。影响LFIA整体性能的因素之一是流体流速,因此,希望在多孔介质中保持可预测的流体速度。本研究的主要目的是建立一个统计模型,估计任何给定环境条件下多孔介质中的流体速度,使我们能够确定实现理想多孔介质中流体速度的最佳设计参数。
{"title":"Effects of relative humidity, temperature, and geometry on fluid flow rate in lateral flow immunoassays","authors":"Nipun Thamatam, J. Christen","doi":"10.1109/HI-POCT45284.2019.8962702","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962702","url":null,"abstract":"Lateral Flow Immunoassays (LFIAs) are among the most successful Point of Care (POC) tests. However, factors like reagent stability, reaction rates, and binding kinetics limit the performance and robustness of LFIAs. One of the factors that affects the overall performance of LFIA is the fluid flow rate, and hence, it is desirable to maintain a predictable fluid velocity in porous media. The main objective of this study is to build a statistical model that estimates the fluid velocity in porous media for any given ambient condition to enable us to determine the optimal design parameters for achieving a desired fluid velocity in porous media.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133234261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mobile and Efficient Temperature and Humidity Control Chamber for Point-of-Care Diagnostics 移动和高效的温度和湿度控制室的点护理诊断
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962889
Brittany Hertneky, J. Eger, Mark S. Bailly, J. Christen
Point-of-care (PoC) testing systems aim to bring affordable and convenient diagnostics to resource limited locations. In our previous work in detecting human papilloma virus (HPV) via lateral flow immunoassays and fluorescence detection, we determined that the performance of the assay depends on the temperature and humidity. Thus, we need to maintain a fixed environment for the assay to produce reliable results. Therefore, we define the need for a portable, climate-controlled chamber for field work in low resource settings. By combining low-cost electronics and household items, a simple feedback loop is designed to regulate the internal conditions of the testing environment. The ability of our chamber to maintain a desired climate will be tested for accuracy and stability to ensure that it is competent for in-field usage.
即时检测系统旨在为资源有限的地区提供负担得起的便捷诊断。在我们之前通过侧流免疫测定和荧光检测检测人乳头瘤病毒(HPV)的工作中,我们确定该测定的性能取决于温度和湿度。因此,我们需要维持一个固定的环境,以产生可靠的结果。因此,我们定义了在低资源环境下进行现场工作的便携式、气候控制室的需求。通过结合低成本的电子产品和家用物品,设计了一个简单的反馈回路来调节测试环境的内部条件。我们的腔室维持所需气候的能力将进行准确性和稳定性测试,以确保它能够胜任现场使用。
{"title":"Mobile and Efficient Temperature and Humidity Control Chamber for Point-of-Care Diagnostics","authors":"Brittany Hertneky, J. Eger, Mark S. Bailly, J. Christen","doi":"10.1109/HI-POCT45284.2019.8962889","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962889","url":null,"abstract":"Point-of-care (PoC) testing systems aim to bring affordable and convenient diagnostics to resource limited locations. In our previous work in detecting human papilloma virus (HPV) via lateral flow immunoassays and fluorescence detection, we determined that the performance of the assay depends on the temperature and humidity. Thus, we need to maintain a fixed environment for the assay to produce reliable results. Therefore, we define the need for a portable, climate-controlled chamber for field work in low resource settings. By combining low-cost electronics and household items, a simple feedback loop is designed to regulate the internal conditions of the testing environment. The ability of our chamber to maintain a desired climate will be tested for accuracy and stability to ensure that it is competent for in-field usage.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123012427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Scoring System for Conditioning and Wellness Assessment in Athletic Population 运动人群调节与健康评估评分系统
Pub Date : 2019-11-01 DOI: 10.1109/HI-POCT45284.2019.8962720
B. Moatamed, Sajad Darabi, M. Sarrafzadeh
Athletic performance is multifaceted, and it is affected by a wide range of factors. Athletes and coaches are interested in collecting as much data as possible to provide insight into performance and training effectiveness. However, it can be difficult for athletes to identify a relationship between these factors and their performance, and even more difficult for a coach who may be responsible for monitoring dozens of metrics in dozens of athletes. Here we outline an approach for condensing a range of wellness factors into a single score, as well as a method for condensing jump height consistency and improvement into a separate performance score. These scoring systems allow for wellness and performance to be evaluated at a glance, allowing for early intervention to reduce injury, an understanding of performance, and effective training.
运动成绩是多方面的,它受到各种因素的影响。运动员和教练都有兴趣收集尽可能多的数据,以深入了解表现和训练效果。然而,运动员很难确定这些因素与他们的表现之间的关系,而对于负责监控几十个运动员的几十个指标的教练来说,就更难了。在这里,我们概述了一种将一系列健康因素浓缩为单个分数的方法,以及将跳跃高度一致性和改进浓缩为单独的性能分数的方法。这些评分系统可以一目了然地评估健康和表现,允许早期干预以减少伤害,了解表现和有效的训练。
{"title":"Scoring System for Conditioning and Wellness Assessment in Athletic Population","authors":"B. Moatamed, Sajad Darabi, M. Sarrafzadeh","doi":"10.1109/HI-POCT45284.2019.8962720","DOIUrl":"https://doi.org/10.1109/HI-POCT45284.2019.8962720","url":null,"abstract":"Athletic performance is multifaceted, and it is affected by a wide range of factors. Athletes and coaches are interested in collecting as much data as possible to provide insight into performance and training effectiveness. However, it can be difficult for athletes to identify a relationship between these factors and their performance, and even more difficult for a coach who may be responsible for monitoring dozens of metrics in dozens of athletes. Here we outline an approach for condensing a range of wellness factors into a single score, as well as a method for condensing jump height consistency and improvement into a separate performance score. These scoring systems allow for wellness and performance to be evaluated at a glance, allowing for early intervention to reduce injury, an understanding of performance, and effective training.","PeriodicalId":269346,"journal":{"name":"2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131663471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
2019 IEEE Healthcare Innovations and Point of Care Technologies, (HI-POCT)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1