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Operational Research Capacity Building through the Structured Operational Research and Training Initiative (SORT IT) Model in Myanmar: National Operational Research Course (2016-17) 缅甸通过结构化运筹学和培训计划(SORT IT)模式进行运筹学能力建设:国家运筹学课程(2016-17)
Pub Date : 2019-04-30 DOI: 10.34299/mhsrj.00915
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引用次数: 0
Comparison of Two Bedside Methods for Determination of Whole-blood Clotting Times in Assessing Coagulopathy in Russell’s Viper Bites 两种床边测定全血凝血时间评估毒蛇咬伤凝血功能的比较
Pub Date : 2019-04-30 DOI: 10.34299/mhsrj.00929
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引用次数: 0
Neurological Changes of Adults Residing in Lead Exposed Environment of Myeik Township 梅耶克镇铅暴露环境中成人神经系统的变化
Pub Date : 2019-04-30 DOI: 10.34299/mhsrj.00923
Lead crosses blood brain barrier and adversely affects the cognitive function, causing impairment of neuropsychological functions. Most of the lead poisonings are asymptomatic and subclinical cases. A cross-sectional analytical study was designed to assess the neurological changes of adults, aged between 20 to 45 years old, residing in lead exposed environment of Myeik Township. The study focused on the cognitive and psychomotor ability of people who lived in those areas at least one year. A total of 95 subjects were interviewed by using the structured questionnaires for assessment of cognitive and psychomotor ability by well-trained researchers. The mean age of all participants was 32.7±8.5 years. The average duration of stay in these areas was approximately 20 years (maximum duration=47 years). The blood lead level was measured by graphite furnace Atomic Absorption Spectrophotometer. The mean blood lead level of all participants was 19.91±1.8 µg/dl. All the participants were divided into two groups: lower blood lead group (blood lead <10 µg/dl) (n=37) and higher blood lead group (blood lead ≥10 µg/dl) (n=58). The cognitive function was assessed by using three subtests (digit span, visual memory and paired associate learning) from the General Memory Scale. The mean scores were (10.51± 2.0, 5.59±0.5 and 20.01±8.3) in lowerblood lead and (9.55±1.8, 5.12±0.7 and 15.23±5.2) in higher lead group, respectively. In addition, the mean total score of cognitive ability test in lower blood lead group was (36.12±9.5) and higher group was (29.90±5.8). All 3 test scores and total scores were significantly lower in higher blood lead group and it could be concluded that the higher the blood lead level, the lower the cognitive ability. To assess psychomotor ability, we used digit symbol, Bourdon-Wiersma vigilance tests and Santa-Ana dexteritytest. Among these three tests, the mean scores of Santa-Ana dexterity test (dominant hand) was significantly longer duration (54.40±10.9 vs. 59.46±10.18) in higher blood lead group than in lower blood lead group. All these findings pointed out that lead intoxication would reduce not only cognitive ability but also psychomotor ability
铅穿过血脑屏障,对认知功能产生不良影响,导致神经心理功能受损。大多数铅中毒是无症状和亚临床病例。采用横断面分析方法,对米耶克镇20 ~ 45岁铅暴露环境中成年人的神经功能变化进行了评价。这项研究的重点是在这些地区居住至少一年的人的认知和精神运动能力。由训练有素的研究人员对95名被试进行认知和精神运动能力评估。所有参与者的平均年龄为32.7±8.5岁。在这些地区的平均停留时间约为20年(最长停留时间为47年)。采用石墨炉原子吸收分光光度计测定血铅水平。所有参与者的平均血铅水平为19.91±1.8µg/dl。所有参与者分为两组:低血铅组(血铅<10µg/dl) (n=37)和高血铅组(血铅≥10µg/dl) (n=58)。认知功能通过一般记忆量表中的三个子测试(数字广度、视觉记忆和配对联想学习)进行评估。低铅组平均得分分别为(10.51±2.0、5.59±0.5、20.01±8.3)分,高铅组平均得分分别为(9.55±1.8、5.12±0.7、15.23±5.2)分。低血铅组认知能力测试平均总分为(36.12±9.5)分,高血铅组平均总分为(29.90±5.8)分。血铅水平越高,认知能力越低,血铅水平越高,认知能力越低。采用数字符号、Bourdon-Wiersma警觉性测验和Santa-Ana灵巧性测验评估精神运动能力。在三项测试中,高血铅组Santa-Ana灵巧测试(优势手)的平均得分(54.40±10.9比59.46±10.18)明显长于低血铅组。这些结果表明,铅中毒不仅会降低认知能力,而且会降低精神运动能力
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引用次数: 0
Contribution and Constraints for the Involvement of People Living with HIV in HIV Prevention and Control Activities: A Qualitative Study at Mandalay Region, 2016 艾滋病毒感染者参与艾滋病毒预防和控制活动的贡献和限制:曼德勒地区的定性研究,2016
Pub Date : 2019-04-30 DOI: 10.34299/mhsrj.00919
There were nearly 170 positive self-help groups of people living with HIV (PLHIV) in 2013 in Myanmar. This study was conducted at Mandalay City and two townships from Mandalay Region during 2016 to assess the contribution of PLHIV in HIV prevention and control related activities, and identify the challenges for the sustainability of their contribution. Seven focus group discussions with six to seven PLHIV in each group, eight indepth interviews with leaders of HIV positive groups, and two key informant interviews with team leaders of HIV/AIDS were conducted. The average age of respondents was 40 years, male and female ratio was 1:5. The average years of involvement in HIV/AIDS-related activities was 4 years. Generally, PLHIV were very supportive especially to the AIDS/ STD teams which have limited human resources. The achievement of PLHIV involvement could be mainly seen in condom promotion and distribution to vulnerable groups, HIV-test counseling, supporting PLHIV from hard-to-reach areas and with poor socio-economic conditions, assisting in antiretroviral therapy (ART) provision at AIDS/STD teams, home-based care for the HIV positive adult and children, and referring people to get HIV tested and ART treatment. Areas and activities which need to be focused were also reported. The key challenges for the sustainability of their contribution were poor resource of basic equipments and facilities especially the place and funding for office, the lower interest of PLHIV and poor technical knowledge to develop income generation activities, the changing attitudes of PLHIV on their involvement, and uncertain future plans of PLHIV groups. To conclude, the challenges among PLHIV groups should be addressed by National AIDS Programme.
2013年,缅甸有近170个艾滋病毒感染者(PLHIV)阳性自助小组。该研究于2016年在曼德勒市和曼德勒省的两个乡镇进行,以评估艾滋病毒携带者在艾滋病毒预防和控制相关活动中的贡献,并确定其贡献的可持续性面临的挑战。每组进行7次焦点小组讨论,每组6 ~ 7名HIV感染者,对HIV阳性组负责人进行8次深度访谈,对HIV/AIDS小组负责人进行2次关键线人访谈。受访者平均年龄40岁,男女比例为1:5。参与艾滋病毒/艾滋病相关活动的平均年数为4年。总的来说,艾滋病毒感染者是非常支持的,特别是对人力资源有限的艾滋病/性病小组。艾滋病毒感染者参与工作的成果主要体现在向弱势群体推广和分发避孕套、艾滋病毒检测咨询、支持来自难以到达地区和社会经济条件差的地区的艾滋病毒感染者、协助艾滋病/性病治疗小组提供抗逆转录病毒治疗(ART)、为艾滋病毒阳性成人和儿童提供家庭护理,以及转介人们接受艾滋病毒检测和抗逆转录病毒治疗。还报告了需要重点关注的领域和活动。他们的贡献的可持续性面临的主要挑战是基本设备和设施资源匮乏,特别是办公场所和资金,艾滋病毒感染者的兴趣较低,发展创收活动的技术知识匮乏,艾滋病毒感染者对其参与的态度不断变化,以及艾滋病毒感染者群体未来计划的不确定。总之,国家艾滋病规划应解决艾滋病毒感染者群体面临的挑战。
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引用次数: 0
Determination of Lead Content in Red Colored Lipsticks from Mandalay Market by Flame Atomic Absorption Spectrophotometer 火焰原子吸收分光光度法测定曼德勒市售红色口红中铅含量
Pub Date : 2018-12-31 DOI: 10.34299/mhsrj.30.03.0045
Theeoo Lwin, K. Chit, K. M. Oo, Khaing Zar Wai, Cho Cho Lwin, Wah Wah Oo
Red colored lipstick is the most widely used cosmetic product. Although lipstick gives a lot of social, psychological and therapeutic benefits, it may harm the consumers. Because some lipsticks contain a considerable amount of heavy metal especially lead. Lead is being used in lipstick mainly for the pigments required to obtain needed colors. Lead accumulates in the body over time and lead-containing lipstick applied several times a day, every day, combined with lead in water and other sources, could add up to significant exposure levels. Therefore, this study was aimed to determine lead content in red colored lipsticks from market. This study was laboratorybased, analytical study by using 25 lipstick samples. Red colored lipsticks were bought from Mandalay Market by random sampling procedure and they were completely coded to avoid the bias. Then, lead content in coded samples was determined by Flame AAS according to International Conference on Harmonization (ICH) guideline. Lead contents of 88% of the lipsticks samples were more than specified limit (20 ppm) of Food and Drug Administration, United States. All of them, lead content was highest in counterfeit lipsticks group. Among the tested lipstick samples, lipstick with lowest lead content was LE-RL 01 (15.74 ppm) and the lipstick with highest lead content was CF-RL 01(60.09 ppm). In conclusion, lead contents of red colored lipsticks (22 out of 25) from market samples were higher than allowable limit (20 ppm).
红色口红是使用最广泛的化妆品。虽然口红给社会、心理和治疗带来了很多好处,但它可能会伤害消费者。因为有些口红含有相当多的重金属,尤其是铅。铅被用于口红中,主要是作为获得所需颜色所需的颜料。随着时间的推移,铅会在体内积累,每天涂几次含铅的口红,再加上水中和其他来源的铅,可能会导致大量接触铅。因此,本研究旨在测定市售红色口红中的铅含量。本研究以实验室为基础,通过使用25个口红样品进行分析研究。红色口红是通过随机抽样程序从曼德勒市场购买的,它们被完全编码以避免偏差。然后,根据国际协调会议(ICH)的指导方针,采用火焰原子吸收法测定编码样品中的铅含量。88%的口红样品铅含量超过美国食品及药物管理局的规定限量(20ppm)。其中,假冒口红组铅含量最高。在检测的口红样品中,铅含量最低的口红为LE-RL 01(15.74 ppm),铅含量最高的口红为CF-RL 01(60.09 ppm)。结果显示,25只口红中有22只的含铅量超过了允许限量(20ppm)。
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引用次数: 1
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Myanmar Health Sciences Research Journal
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