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1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference最新文献

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Quantitative Volume Analysis Of Coronary Vessel Systems By 3-D Reconstruction From Biplane Angiograms 冠状血管系统三维重建的定量体积分析
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701838
A. Wahle, E. Wellnhofer, I. Mugaragu, H. U. Sauer, H. Oswald, E. Fleck
Quantitative evaluations on coronary vessel systems are of increasing importance in cardio-vascular diagnosis, therapy planning and surgical verification. Local evaluations, like stenosis analysis, are already available with sufficient accuracy. On the other hand, global evaluations on vessel segments or vessel subsystems are not yet common. Especially for the &agnosis of diffuse coronary artery diseases, we combined a 3-D reconstruction system operating on biplane angiogram with a length/volume calculation. The 3-D reconstruction results in a 3-D model of the coronary vessel system, consisting of the vessel skeleton and a discrete number of contours. To obtain a most accurate model, we focussed on exact geometry determination. Several algorithms for calculating missing geometric parameters and correcting remaining geometry errors were implemented and verified. The length/volume evaluation can be performed either on single vessel segments, on a set of segments, or on sub-trees. A volume model based on generalized elliptical conic sections is created for the selected segments. Volumes and lengths (measured along the vessel course) of those elements are summed up. In this way, the morphological parameters of a vessel subsystem can be set in relation to the parameters of the supplying segment proximal to it. These relations allow objective assessments of diffuse coronary artery diseases. sional measures defined on sets of sub-trees was selected and tested clinically. IT. 3-D RECONSTRUCTION A . Imaging Geometry and Point Reconstruction Standard biplane angiographic equipment consists of two x-ray systems having a common coordinate system [l]. In conventional methods, a fixed rotational origin of both systems is assumed where the projection axes intersect, the isocenter. For volume measurements, we need a very high reconstruction accuracy, because linear reconstruction errors raise to the third power. The classic isocenvic model could not satisfy this requirement: there is neither a stable isocenter, nor is there an adequate way to determine the required distances manually [21. In our geometric model, we use a variable iso-axis instead of a fixed isocenter. The distance of the projection axes creates a unique iso-axis orthogonal to both of them (fig. 2). The locations of x-ray sources and image intensifiers are determined in terms of distances to this iso-axis. The origin of the world coordinate system is defined as the weighted middle of the projection axes distance on the iso-axis. The angulation is obtained conventionally as a sequence of rotations, con-
冠状动脉系统的定量评估在心血管诊断、治疗计划和手术验证中越来越重要。局部评估,如狭窄分析,已经具有足够的准确性。另一方面,对船舶分段或船舶子系统的整体评估还不常见。特别是对于弥漫性冠状动脉疾病的诊断,我们将双翼血管造影三维重建系统与长度/体积计算相结合。三维重建的结果是冠状动脉系统的三维模型,由血管骨架和离散数量的轮廓组成。为了获得最精确的模型,我们着重于精确的几何形状确定。实现并验证了几种计算缺失几何参数和校正剩余几何误差的算法。长度/体积评估可以在单个容器段上进行,也可以在一组段上进行,也可以在子树上进行。对所选线段建立了基于广义椭圆圆锥截面的体积模型。这些元素的体积和长度(沿着船舶航线测量)被总结。这样,血管子系统的形态参数可以相对于其近端的供血节的参数进行设置。这些关系有助于对弥漫性冠状动脉疾病进行客观评估。选择在子树集上定义的纵向测量并进行临床测试。它。3-d重建标准的双翼血管造影设备由两个具有共同坐标系的x射线系统组成[1]。在传统的方法中,假设两个系统的一个固定的旋转原点在投影轴相交的地方,即等心。对于体积测量,我们需要非常高的重建精度,因为线性重建误差会上升到三次方。经典等心模型不能满足这一要求:既没有稳定的等心,也没有足够的方法来手动确定所需的距离[21]。在我们的几何模型中,我们使用可变的等轴而不是固定的等中心。投影轴的距离创建了一个与它们正交的独特等轴(图2)。x射线源和图像增强器的位置是根据到该等轴的距离确定的。世界坐标系的原点被定义为投影轴距离在等轴上的加权中点。成角通常是由一系列的旋转得到的
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引用次数: 17
Attenuation correction in 3D PET-comparison of the direct and the reconstruction-reprojection method 三维pet衰减校正-直接法与重建-重投影法的比较
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373523
T. Beyer, D. Townsend, M. Defrise
Two methods for attenuation correction in 3D positron emission tomography have been compared. The first method, which is referred to here as the direct method, estimates the attenuation correction factors from the ratio of the blank and transmission scan. The second method, referred to here as the reconstruction-reprojection method is based on the reconstruction and forward projection of a transmission image. Using computer simulation, it is shown that the reconstruction-reprojection method significantly increases the signal-to-noise ratio in the corrected 3D emission scan, but leads to only a limited improvement in the image. A similar image signal-to-noise ratio can be obtained using the direct method, if the transmission scan is first convolved with a 3-point smoothing window. The consequence of the loss of resolution caused by this smoothing is analysed using a simulated chest phantom.<>
比较了三维正电子发射层析成像中衰减校正的两种方法。第一种方法,这里称为直接法,从空白扫描和透射扫描的比值估计衰减校正系数。第二种方法,这里称为重建-重投影方法,是基于传输图像的重建和正演投影。计算机仿真结果表明,重建-重投影方法在校正后的三维发射扫描中显著提高了信噪比,但对图像的改善有限。如果首先将传输扫描与3点平滑窗口进行卷积,则可以使用直接方法获得类似的图像信噪比。使用模拟的胸部幻影分析了由这种平滑引起的分辨率损失的后果。
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引用次数: 4
An Object-oriented Dataflow Software Development Tool For Medical Image Analysis 面向对象的医学图像分析数据流软件开发工具
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701848
M. S. Atkins, B. Johnston, T. Zuk, T. Arden
Developers of new algorithms typically require an interactive environment in which the image data can be passed through various operators, some of which may involve feedback, synchronization, merging and conditional control strategies. This paper describes how the dataflow methodology of a pictorial object-oriented software development tool called WIT has greatly simplified the prototyping and testing of our new image registration and segmentation methods. WIT allows the user to draw a dataflow graph by linking operators in a CAD-like manner. We describe the main features of WIT, and show dataflow graphs for two medical image analysis algorithms; the 3D registration of PET scans into a common coordinate space, and tissue segmentation in MRI images where we are looking at quantitation of tumour volumes.
新算法的开发人员通常需要一个交互式环境,在这个环境中,图像数据可以通过各种操作来传递,其中一些操作可能涉及反馈、同步、合并和条件控制策略。本文描述了一种称为WIT的图形面向对象软件开发工具的数据流方法如何极大地简化了我们的新图像配准和分割方法的原型设计和测试。WIT允许用户通过以类似cad的方式链接操作符来绘制数据流图。描述了WIT的主要特征,给出了两种医学图像分析算法的数据流图;PET扫描的三维配准到一个共同的坐标空间,以及MRI图像中的组织分割,我们正在研究肿瘤体积的定量。
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引用次数: 0
A Custom CMOS Integrated Circuit For PET Tomograph Front-end Applications 用于PET层析成像前端应用的定制CMOS集成电路
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701771
D. Binkley, M. Paulus, M. Casey, R. Nutt, W. Loeffler, J. Clif, J. M. Rochelle
A custom CMOS integrated circuit has been designed, prototyped, and evaluated for PET tomograph front-end applications. The integrated circuit reduces the size. cost, and power consumption of existing PET frontend circuits by Over a factor of two. The integrated circuit, fabricated in a standard digital, 2 p, double-metal, double-poly, n-well CMOS process, has a die size of 6.6mmx6.4mm and power consumption of under 600 mW. The PET front-end CMOS integrated circuit processes energy, position, and timing information from a BGO block detector containing four photomultiplier tubes. Photomultiplier preamplifiers and variable gain amplifiers are co~ected to summing circuits and gated integrators to provide energy and position (x and y) signals. A constantfraction discriminator, requiring no external delay line, provides a timing output derived from the sum of the four photomultiplier signals. Eight 7- and 8-bit digital-to-analog converters. connected to a readwrite serial data interface, provide gain-control and threshold levels. The measured position, energy, and timing performance (3.05ns FWHM) of the integrated circuit is comparable to existing discrete PET frontend circuits.
一个定制的CMOS集成电路已经设计,原型,并评估PET层析成像前端应用。集成电路减小了尺寸。成本和现有PET前端电路的功耗降低了两倍以上。该集成电路采用标准数字、2p、双金属、双聚、n阱CMOS工艺制造,芯片尺寸为6.6mmx6.4mm,功耗低于600 mW。PET前端CMOS集成电路处理来自包含四个光电倍增管的BGO块探测器的能量,位置和定时信息。光电倍增管前置放大器和可变增益放大器与求和电路和门控积分器共连接,提供能量和位置(x和y)信号。一个常数鉴别器,不需要外部延迟线,提供一个时序输出从四个光电倍增管信号的总和。8个7位和8位数模转换器。连接到一个读写串行数据接口,提供增益控制和阈值水平。测量到的集成电路的位置、能量和时序性能(3.05ns FWHM)与现有的离散PET前端电路相当。
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引用次数: 17
Brain image registration based on cortical contour mapping 基于皮质等高线映射的脑图像配准
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373607
C. Davatzikos, Jerry L Prince, R. Bryan
The authors address the problem of brain image registration, and they present a new, nonlinear registration technique. In the first step of the authors' technique they obtain a point-to-point mapping between the outer cortical contours of the brain images using an elastic string algorithm. In the second step the authors register the two images based on the point-to-point correspondence established in the first step. They propose a new, nonlinear registration transformation, which is based on a spatially variable scaling and relation that can describe highly nonlinear deformations. Finally, the authors test their algorithm on two different registration problems: they first consider the registration of a postmortem photograph of a baboon brain cross-section and then an MR image of approximately the same cross-section.<>
针对脑图像配准问题,提出了一种新的非线性配准技术。在作者技术的第一步中,他们使用弹性字符串算法在大脑图像的外皮层轮廓之间获得点对点映射。在第二步中,作者基于第一步中建立的点对点对应关系对两幅图像进行配准。他们提出了一种新的非线性配准变换,它基于空间变量缩放和关系,可以描述高度非线性变形。最后,作者在两个不同的配准问题上测试了他们的算法:他们首先考虑对狒狒大脑横截面的死后照片进行配准,然后是对大致相同横截面的核磁共振图像进行配准。
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引用次数: 3
Instrumentation And Control Upgrade Planning At Arkansas Nuclear One 阿肯色一号核电站的仪器和控制升级计划
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701795
J. Jehlen, K. Nichols, D. Wilkinson, E. Brown
fNTRODlJCTION EPRI has undertaken the Instrumentation and Control (I&C) Initiative to reduce operations and maintenance (O&M) costs through long term life cycle management planning and to promote the cost effective use of modern technology in nuclear power plant I&C upgrades. A key element in the Initiative is the Demonstration Plant Program. The Demonstration Plant Program was started in 1991 with the goal of establishing comprehensive, integrata I&C maintenance and upgrade planning programs in operating nuclear power plants. The intent of these programs is to develop cost effective solutions to I&C obsolescence problems, and to demonstrate the technology developed under EPRI research and development programs. Currently, EPRI has established demonstration programs at eight plants including:
EPRI已经承担了仪表和控制(I&C)计划,通过长期生命周期管理计划来降低运行和维护(O&M)成本,并促进现代技术在核电站I&C升级中的经济高效使用。该倡议的一个关键要素是示范工厂计划。示范电厂计划始于1991年,其目标是在运行中的核电站建立全面、综合的I&C维护和升级规划方案。这些项目的目的是开发具有成本效益的解决方案,以解决I&C过时的问题,并展示在EPRI研究和开发项目下开发的技术。目前,EPRI已经在八个工厂建立了示范项目,包括:
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引用次数: 0
A Proposal Of Accurate Scatter Correction Method Considering Energy Spectra Of Scattered Photons In Single Photon Emission CT 一种考虑单光子发射CT散射光子能谱的精确散射校正方法
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701863
A. Chugo, K. Ogawa
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引用次数: 0
Energy Transfer Mechanism In Gd/sub 2/(SiO/sub 4/)O:Ce Scintillators Gd/ sub2 /(SiO/ sub4 /)O:Ce闪烁体中的能量传递机理
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701640
H. Suzuki, T. Tombrello, C. Melcher, J. Schweitzer
The scintillation decay of cerium-doped gadolinium oxyorthosilicate Gd/sub 2/(SiO/sub 4/)O:Ce is lengthened by the energy transfer from Gd to Ce. To investigate the role of the Gd in the scintillation processes, the Gd was partially replaced by optically inactive rare earth elements, Y and Lu, and the effective transfer rates from Gd to Ce were measured as a function of Gd and Ce concentrations using UV- and gamma-ray excitations. The data clearly indicate the dilution of the Gd by the Y and the Lu further lengthens the migration time through the Gd in the energy transfer process from Gd to Ce. >
掺铈氧化硅酸钆Gd/sub 2/(SiO/sub 4/)O:Ce的闪烁衰减由于Gd向Ce的能量转移而延长。为了研究Gd在闪烁过程中的作用,我们将Gd部分替换为不具有光学活性的稀土元素Y和Lu,并利用紫外和伽马射线激发测量了Gd到Ce的有效转移速率作为Gd和Ce浓度的函数。数据清楚地表明,在从Gd到Ce的能量传递过程中,Y和Lu对Gd的稀释进一步延长了Gd通过Gd的迁移时间。>
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引用次数: 29
3D segmentation of Ct images on a massively parallel computer 基于大规模并行计算机的Ct图像三维分割
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.702011
S. Wegner, H. Oswald, E. Fleck, R. Felix
For 3D scenes a 3D segmentation technique on a massively parallel computer is described and tested on CT image sequences. The approach is based on a volume growing technique driven by statistical features and a model depending on characteristic object parameters. The volumes of interest are specified interactively and used as seed volumes for the growing algorithm. An estimation technique is employed to calculate several statistical properties of these seed volumes. The required homogeneity criterion for each volume is then obtained in regard to the estimated statistics and the model of the object. These segmentation results are handled by a 3D morphological operator. Due to practical considerations the approach has been implemented on a massively parallel SIMD (single instruction multiple data) machine, the MasPar Mp1102.
针对三维场景,描述了一种大规模并行计算机上的三维分割技术,并在CT图像序列上进行了测试。该方法基于统计特征驱动的体积增长技术和基于特征对象参数的模型。感兴趣的体积以交互方式指定,并用作生长算法的种子体积。采用一种估计技术计算了这些种子体积的几种统计性质。然后根据估计的统计量和对象的模型获得每个体积所需的均匀性准则。这些分割结果由三维形态学算子处理。由于实际考虑,该方法已在大规模并行SIMD(单指令多数据)机器上实现,即MasPar Mp1102。
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引用次数: 0
Distance-dependent restoration filtering of dual photopeak window scatter compensated SPECT images 双光峰窗散射补偿SPECT图像的距离依赖恢复滤波
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373522
S. Glick, D. de Vries, Matt A. King
A non-iterative SPECT reconstruction method is presented which consists of pre-processing the projection data for compensation of scatter, attenuation and the detector response prior to ramp filtered backprojection. Scatter is compensated for using the dual-photopeak window (DPW) method, attenuation is compensated for using Bellini's method, and compensation for the non-stationary detector response and noise suppression is performed with a frequency distance principle (FDP) Wiener filter. This approach was compared to a number of different processing methods using a Monte Carlo simulation study of an anthropomorphic digitized phantom of the liver and spleen. Compared to Butterworth smoothing, the DPW/FDP Wiener filtering method can provide a substantial increase in contrast with a noise increase ranging from minimal to moderate depending on the cut-off frequency of the Butterworth filter.<>
提出了一种非迭代的SPECT重建方法,该方法在斜坡滤波后的反投影前对投影数据进行预处理,补偿散射、衰减和检测器响应。采用双光峰窗(DPW)法对散射进行补偿,采用Bellini法对衰减进行补偿,采用频率距离原理(FDP)维纳滤波器对非平稳检测器响应进行补偿和噪声抑制。该方法与许多不同的处理方法进行了比较,使用蒙特卡罗模拟研究了肝脏和脾脏的拟人化数字化幻影。与巴特沃斯平滑相比,DPW/FDP维纳滤波方法可以提供大量的增加,而噪声的增加范围从最小到中等,这取决于巴特沃斯滤波器的截止频率。
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引用次数: 3
期刊
1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference
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