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1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference最新文献

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3D segmentation of Ct images on a massively parallel computer 基于大规模并行计算机的Ct图像三维分割
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.702011
S. Wegner, H. Oswald, E. Fleck, R. Felix
For 3D scenes a 3D segmentation technique on a massively parallel computer is described and tested on CT image sequences. The approach is based on a volume growing technique driven by statistical features and a model depending on characteristic object parameters. The volumes of interest are specified interactively and used as seed volumes for the growing algorithm. An estimation technique is employed to calculate several statistical properties of these seed volumes. The required homogeneity criterion for each volume is then obtained in regard to the estimated statistics and the model of the object. These segmentation results are handled by a 3D morphological operator. Due to practical considerations the approach has been implemented on a massively parallel SIMD (single instruction multiple data) machine, the MasPar Mp1102.
针对三维场景,描述了一种大规模并行计算机上的三维分割技术,并在CT图像序列上进行了测试。该方法基于统计特征驱动的体积增长技术和基于特征对象参数的模型。感兴趣的体积以交互方式指定,并用作生长算法的种子体积。采用一种估计技术计算了这些种子体积的几种统计性质。然后根据估计的统计量和对象的模型获得每个体积所需的均匀性准则。这些分割结果由三维形态学算子处理。由于实际考虑,该方法已在大规模并行SIMD(单指令多数据)机器上实现,即MasPar Mp1102。
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引用次数: 0
A Custom CMOS Integrated Circuit For PET Tomograph Front-end Applications 用于PET层析成像前端应用的定制CMOS集成电路
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701771
D. Binkley, M. Paulus, M. Casey, R. Nutt, W. Loeffler, J. Clif, J. M. Rochelle
A custom CMOS integrated circuit has been designed, prototyped, and evaluated for PET tomograph front-end applications. The integrated circuit reduces the size. cost, and power consumption of existing PET frontend circuits by Over a factor of two. The integrated circuit, fabricated in a standard digital, 2 p, double-metal, double-poly, n-well CMOS process, has a die size of 6.6mmx6.4mm and power consumption of under 600 mW. The PET front-end CMOS integrated circuit processes energy, position, and timing information from a BGO block detector containing four photomultiplier tubes. Photomultiplier preamplifiers and variable gain amplifiers are co~ected to summing circuits and gated integrators to provide energy and position (x and y) signals. A constantfraction discriminator, requiring no external delay line, provides a timing output derived from the sum of the four photomultiplier signals. Eight 7- and 8-bit digital-to-analog converters. connected to a readwrite serial data interface, provide gain-control and threshold levels. The measured position, energy, and timing performance (3.05ns FWHM) of the integrated circuit is comparable to existing discrete PET frontend circuits.
一个定制的CMOS集成电路已经设计,原型,并评估PET层析成像前端应用。集成电路减小了尺寸。成本和现有PET前端电路的功耗降低了两倍以上。该集成电路采用标准数字、2p、双金属、双聚、n阱CMOS工艺制造,芯片尺寸为6.6mmx6.4mm,功耗低于600 mW。PET前端CMOS集成电路处理来自包含四个光电倍增管的BGO块探测器的能量,位置和定时信息。光电倍增管前置放大器和可变增益放大器与求和电路和门控积分器共连接,提供能量和位置(x和y)信号。一个常数鉴别器,不需要外部延迟线,提供一个时序输出从四个光电倍增管信号的总和。8个7位和8位数模转换器。连接到一个读写串行数据接口,提供增益控制和阈值水平。测量到的集成电路的位置、能量和时序性能(3.05ns FWHM)与现有的离散PET前端电路相当。
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引用次数: 17
An Object-oriented Dataflow Software Development Tool For Medical Image Analysis 面向对象的医学图像分析数据流软件开发工具
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701848
M. S. Atkins, B. Johnston, T. Zuk, T. Arden
Developers of new algorithms typically require an interactive environment in which the image data can be passed through various operators, some of which may involve feedback, synchronization, merging and conditional control strategies. This paper describes how the dataflow methodology of a pictorial object-oriented software development tool called WIT has greatly simplified the prototyping and testing of our new image registration and segmentation methods. WIT allows the user to draw a dataflow graph by linking operators in a CAD-like manner. We describe the main features of WIT, and show dataflow graphs for two medical image analysis algorithms; the 3D registration of PET scans into a common coordinate space, and tissue segmentation in MRI images where we are looking at quantitation of tumour volumes.
新算法的开发人员通常需要一个交互式环境,在这个环境中,图像数据可以通过各种操作来传递,其中一些操作可能涉及反馈、同步、合并和条件控制策略。本文描述了一种称为WIT的图形面向对象软件开发工具的数据流方法如何极大地简化了我们的新图像配准和分割方法的原型设计和测试。WIT允许用户通过以类似cad的方式链接操作符来绘制数据流图。描述了WIT的主要特征,给出了两种医学图像分析算法的数据流图;PET扫描的三维配准到一个共同的坐标空间,以及MRI图像中的组织分割,我们正在研究肿瘤体积的定量。
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引用次数: 0
Attenuation correction in 3D PET-comparison of the direct and the reconstruction-reprojection method 三维pet衰减校正-直接法与重建-重投影法的比较
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373523
T. Beyer, D. Townsend, M. Defrise
Two methods for attenuation correction in 3D positron emission tomography have been compared. The first method, which is referred to here as the direct method, estimates the attenuation correction factors from the ratio of the blank and transmission scan. The second method, referred to here as the reconstruction-reprojection method is based on the reconstruction and forward projection of a transmission image. Using computer simulation, it is shown that the reconstruction-reprojection method significantly increases the signal-to-noise ratio in the corrected 3D emission scan, but leads to only a limited improvement in the image. A similar image signal-to-noise ratio can be obtained using the direct method, if the transmission scan is first convolved with a 3-point smoothing window. The consequence of the loss of resolution caused by this smoothing is analysed using a simulated chest phantom.<>
比较了三维正电子发射层析成像中衰减校正的两种方法。第一种方法,这里称为直接法,从空白扫描和透射扫描的比值估计衰减校正系数。第二种方法,这里称为重建-重投影方法,是基于传输图像的重建和正演投影。计算机仿真结果表明,重建-重投影方法在校正后的三维发射扫描中显著提高了信噪比,但对图像的改善有限。如果首先将传输扫描与3点平滑窗口进行卷积,则可以使用直接方法获得类似的图像信噪比。使用模拟的胸部幻影分析了由这种平滑引起的分辨率损失的后果。
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引用次数: 4
Atlas generated generalized ROIs for use in functional neuroimaging Atlas生成广义roi用于功能性神经成像
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373606
L. Thurfjell, C. Bohm
The interpretation of functional neuroimaging data can in many cases be facilitated by comparisons with simulated data corresponding to the measuring situation. A computerized brain atlas is used to provide information regarding the spatial extent of the object being imaged. This knowledge combined with information about the resolution of the imaging device expressed as point spread functions is used to calculate a simulated image of the object. This image can be regarded as a generalized region of interest (ROI) containing information of the object as viewed by the specific instrument. Generalized ROIs are used to automatically determine boundaries of ordinary ROIs and to provide recovery coefficients to compensate for partial volume effects. Simulations can also be used to generate three-dimensional data sets where different uptake levels have been assigned to different anatomical structures.<>
在许多情况下,通过与与测量情况相对应的模拟数据进行比较,可以促进功能性神经成像数据的解释。计算机化的脑图谱用于提供有关被成像对象的空间范围的信息。该知识与表示为点扩展函数的成像设备的分辨率信息相结合,用于计算对象的模拟图像。该图像可以被视为广义感兴趣区域(ROI),其中包含特定仪器所看到的物体信息。广义roi用于自动确定普通roi的边界,并提供恢复系数来补偿部分体积效应。模拟还可用于生成三维数据集,其中不同的摄取水平已分配给不同的解剖结构。
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引用次数: 2
A rotating and squashing projector-backprojector pair for fan-beam and cone-beam iterative algorithms 扇形波束和锥波束迭代算法的旋转和压缩投影-反向投影对
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373629
G. L. Zeng, Y. Hsieh, G. Gullberg
The authors propose and implement a rotating-and-squashing projector-backprojector pair for fan-beam and cone-beam iterative algorithms. The motivation of their investigation is to significantly reduce both computation time and reconstruction artifacts when implementing attenuation, geometric and scatter correction models. At each projection angle, the authors' projector/backprojector first rotates the image volume so that the front face of the volume is parallel to the detector, then squashes the image volume so that the fan-beam and cone-beam rays are converted into parallel rays. In the authors' implementation, these two steps are combined and they only interpolate the voxel values once. The projection operation is achieved by a simple summation, and the backprojection operation is achieved by copying the projection array to the image volume. Another advantage of this projector/backprojector is that the system point response function can be deconvolved via the fast Fourier transform using the shift-invariant property of the point response function when the voxel-to-detector distance is constant. At each projection angle, the authors rotate and squash the image volume using interpolations. This causes smoothing of the image. However, this smoothing can be modeled as a point spread function and be deconvolved. The fan-beam and cone-beam rotating-and-squashing projector/backprojector have been implemented on a SPECT system for the EM-ML algorithm.<>
作者提出并实现了一种用于扇束和锥束迭代算法的旋转-压缩投影-反向投影对。他们研究的动机是在实现衰减、几何和散射校正模型时显著减少计算时间和重建伪影。在每个投影角度,作者的投影仪/背向投影仪首先旋转成像体,使成像体的正面与探测器平行,然后压扁成像体,使扇束和锥束光线转换成平行光线。在作者的实现中,这两个步骤是结合在一起的,它们只插值体素值一次。投影操作通过简单求和实现,反向投影操作通过将投影数组复制到图像体中实现。这种投影仪/背向投影仪的另一个优点是,当体素到检测器的距离恒定时,利用点响应函数的移位不变性,可以通过快速傅立叶变换对系统点响应函数进行反卷积。在每个投影角度,作者使用插值旋转和压缩图像体积。这会使图像平滑。然而,这种平滑可以建模为点扩展函数并进行反卷积。在EM-ML算法的SPECT系统上实现了扇形波束和锥形波束旋转和压缩投影仪/背向投影仪。
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引用次数: 6
Bias-variance tradeoffs analysis using uniform CR bound for a SPECT system 偏差-方差权衡分析使用统一的CR界为SPECT系统
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373518
M. Usman, A. Hero, J. Fessler, W. Rogers
The authors quantify fundamental bias-variance tradeoffs for the image reconstruction problem in radio-pharmaceutical tomography using Cramer-Rao (CR) bound analysis. The image reconstruction problem is very often biased and the classical or the unbiased CR bound on the mean square error performance of the estimator can not be used. The authors use a recently developed "uniform" CR bound which applies to biased estimators whose bias gradient satisfies a user specified length constraint. The authors demonstrate the use of the "uniform" CR bound for a simple SPECT system using several different examples.<>
作者量化的基本偏差-方差权衡的图像重建问题在放射药物断层扫描使用Cramer-Rao (CR)界分析。图像重建问题往往是有偏的,不能使用估计器均方误差性能的经典或无偏CR界。作者使用了最近发展的“一致”CR界,它适用于偏差梯度满足用户指定长度约束的有偏估计量。作者用几个不同的例子演示了在一个简单的SPECT系统中使用“均匀”CR界。
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引用次数: 6
A simple data loss model for positron camera systems 正电子相机系统的简单数据丢失模型
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373634
L. Eriksson
A simple model to describe data losses in PET cameras is presented. The model is not intended to be used primarily for dead time corrections in existing scanners, even if this may be possible. Instead the model is intended to be used for data simulations in order to determine the figures of merits of future camera systems based on data handling state-of-art solutions. The model assumes the data loss to be factorized into two components, one describing the detector or block-detector performance and the other the remaining data handling such as coincidence determinations, data transfer and data storage. Two modern positron camera systems have been investigated in terms of this model. These are the new Siemens-CTI systems, Ecat Exact and Ecat Exact HR, both with an axial field-of-view (FOV) covering around 15 cm. They both have retractable septa and can acquire data from the whole volume within the FOV and can reconstruct volume image data. An example is given how to use the model for live time calculations in a futuristic large axial FOV cylindrical system.<>
提出了一个描述PET相机数据丢失的简单模型。该模型并不打算主要用于现有扫描仪中的死区时间校正,即使这是可能的。相反,该模型旨在用于数据模拟,以确定基于数据处理最先进解决方案的未来相机系统的优点。该模型假设将数据丢失分解为两个组件,一个描述检测器或块检测器的性能,另一个描述剩余的数据处理,如一致性确定、数据传输和数据存储。用这个模型研究了两个现代正电子相机系统。这些都是新的西门子- cti系统,Ecat Exact和Ecat Exact HR,都具有约15厘米的轴向视场(FOV)。它们都具有可伸缩的隔层,可以在视场内获取整个体的数据,并可以重建体图像数据。给出了如何将该模型用于未来大轴向视场柱面系统实时计算的实例
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引用次数: 42
Brain image registration based on cortical contour mapping 基于皮质等高线映射的脑图像配准
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.373607
C. Davatzikos, Jerry L Prince, R. Bryan
The authors address the problem of brain image registration, and they present a new, nonlinear registration technique. In the first step of the authors' technique they obtain a point-to-point mapping between the outer cortical contours of the brain images using an elastic string algorithm. In the second step the authors register the two images based on the point-to-point correspondence established in the first step. They propose a new, nonlinear registration transformation, which is based on a spatially variable scaling and relation that can describe highly nonlinear deformations. Finally, the authors test their algorithm on two different registration problems: they first consider the registration of a postmortem photograph of a baboon brain cross-section and then an MR image of approximately the same cross-section.<>
针对脑图像配准问题,提出了一种新的非线性配准技术。在作者技术的第一步中,他们使用弹性字符串算法在大脑图像的外皮层轮廓之间获得点对点映射。在第二步中,作者基于第一步中建立的点对点对应关系对两幅图像进行配准。他们提出了一种新的非线性配准变换,它基于空间变量缩放和关系,可以描述高度非线性变形。最后,作者在两个不同的配准问题上测试了他们的算法:他们首先考虑对狒狒大脑横截面的死后照片进行配准,然后是对大致相同横截面的核磁共振图像进行配准。
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引用次数: 3
Instrumentation And Control Upgrade Planning At Arkansas Nuclear One 阿肯色一号核电站的仪器和控制升级计划
Pub Date : 1993-10-31 DOI: 10.1109/NSSMIC.1993.701795
J. Jehlen, K. Nichols, D. Wilkinson, E. Brown
fNTRODlJCTION EPRI has undertaken the Instrumentation and Control (I&C) Initiative to reduce operations and maintenance (O&M) costs through long term life cycle management planning and to promote the cost effective use of modern technology in nuclear power plant I&C upgrades. A key element in the Initiative is the Demonstration Plant Program. The Demonstration Plant Program was started in 1991 with the goal of establishing comprehensive, integrata I&C maintenance and upgrade planning programs in operating nuclear power plants. The intent of these programs is to develop cost effective solutions to I&C obsolescence problems, and to demonstrate the technology developed under EPRI research and development programs. Currently, EPRI has established demonstration programs at eight plants including:
EPRI已经承担了仪表和控制(I&C)计划,通过长期生命周期管理计划来降低运行和维护(O&M)成本,并促进现代技术在核电站I&C升级中的经济高效使用。该倡议的一个关键要素是示范工厂计划。示范电厂计划始于1991年,其目标是在运行中的核电站建立全面、综合的I&C维护和升级规划方案。这些项目的目的是开发具有成本效益的解决方案,以解决I&C过时的问题,并展示在EPRI研究和开发项目下开发的技术。目前,EPRI已经在八个工厂建立了示范项目,包括:
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引用次数: 0
期刊
1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference
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