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Machine learning for food colloids: Novel tools to advance fundamental understanding, stability, texture, and processability 食品胶体的机器学习:促进基本理解,稳定性,质地和可加工性的新工具
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-06-13 DOI: 10.1016/j.cocis.2025.101937
Kelvin Wong , Tarsila Rodrigues Arruda , Keith T. Butler , Stefan Guldin , Stephen Schrettl
Evolving demands for healthier and more sustainable foods require reformulating ingredients and innovating production processes while maintaining sensory quality and shelf-life. Because traditional physics-based models struggle with the multi-scale complexity of food colloids, machine learning (ML) has emerged as a powerful alternative for predicting the behavior of these systems, in which dispersed components critically shape texture and functionality. This article highlights recent ML applications to enhance colloidal stability and rheological properties, demonstrating how supervised and unsupervised algorithms can capture complex, nonlinear relationships. Key examples include neural networks and chemometric models that predict emulsion stability, monitor microstructures, and forecast gel strength. We further discuss how ML-driven approaches reduce time-consuming experimental work and accelerate product innovation. Looking ahead, future opportunities lie in leveraging larger datasets, adopting inverse design strategies, and implementing insights from adjacent fields to deliver the next generation of data-informed, functional food colloids.
对更健康和更可持续的食品不断变化的需求要求重新配制成分和创新生产工艺,同时保持感官质量和保质期。由于传统的基于物理的模型难以应对食物胶体的多尺度复杂性,机器学习(ML)已经成为预测这些系统行为的强大替代方案,在这些系统中,分散的成分对质地和功能的影响至关重要。本文重点介绍了最近在增强胶体稳定性和流变特性方面的机器学习应用,展示了监督和非监督算法如何捕获复杂的非线性关系。关键的例子包括预测乳液稳定性的神经网络和化学计量模型,监测微观结构,预测凝胶强度。我们进一步讨论了机器学习驱动的方法如何减少耗时的实验工作并加速产品创新。展望未来,未来的机会在于利用更大的数据集,采用逆向设计策略,并从邻近领域实施见解,以提供下一代数据信息,功能性食品胶体。
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引用次数: 0
Light-responsive emulsions and dispersions: Design and applications 光响应乳剂和分散体:设计和应用
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-06-07 DOI: 10.1016/j.cocis.2025.101935
Jack W. Avery , Beatrice E. Jones , Gregory N. Smith , Rachel C. Evans
The response of molecules to light can have a dramatic impact on the stability, morphology, and controlled release from emulsions or dispersions. In this review, we discuss the underlying mechanisms enabling light-responsive behaviour, including photoswitching, photodestruction, and photothermal effects, in surfactant- and particle-stabilised emulsions and dispersions of structured lipid nanoparticles. We critically evaluate the recent literature to demonstrate the precise control that can be achieved over a wide range of parameters, including droplet size, stability, and release. Finally, we summarise the emerging applications of these systems, identify current challenges, and suggest future research directions.
分子对光的反应会对乳液或分散体的稳定性、形态和控制释放产生巨大影响。在这篇综述中,我们讨论了在表面活性剂和颗粒稳定乳剂和结构脂质纳米颗粒分散体中实现光响应行为的潜在机制,包括光开关、光破坏和光热效应。我们批判性地评估了最近的文献,以证明可以在广泛的参数范围内实现精确控制,包括液滴大小,稳定性和释放。最后,我们总结了这些系统的新兴应用,确定了当前的挑战,并提出了未来的研究方向。
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引用次数: 0
Microfluidic production of hydrogel-shelled microcapsules and their applications 水凝胶微胶囊的微流控制备及其应用
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-06-07 DOI: 10.1016/j.cocis.2025.101936
Jiwoo Lee , Ji-Won Kim , Shin-Hyun Kim
Hydrogel shells enable precise compartmentalization of aqueous cores while regulating transmembrane molecular transport based on size- and charge-selectivity. Recent advances in droplet microfluidics have enabled the production of monodisperse multiple-emulsion droplets, which serve as ideal templates for hydrogel shell fabrication. This mini-review highlights recent progress in microfluidic emulsion templating for hydrogel shell production and explores optimal design strategies for diverse applications. Hydrogel shells are fabricated using various types of emulsions, with formation mechanisms and material selection tailored to each type. Their applications span drug and cell microcarriers, microreactors, and microsensors, where the composition, structure, and crosslinking density are precisely engineered.
水凝胶壳能够精确区隔水核,同时调节基于大小和电荷选择性的跨膜分子运输。液滴微流体的最新进展使单分散多乳液液滴的生产成为可能,这些液滴可作为水凝胶壳制造的理想模板。本文综述了用于水凝胶壳生产的微流控乳液模板的最新进展,并探讨了各种应用的最佳设计策略。水凝胶壳是由不同类型的乳液制成的,每种类型的形成机制和材料选择都是量身定制的。它们的应用跨越药物和细胞微载体、微反应器和微传感器,其中的组成、结构和交联密度是精确设计的。
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引用次数: 0
Aqueous two-phase emulsion systems in 3D cell culture 三维细胞培养中的水相两相乳液体系
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-06-06 DOI: 10.1016/j.cocis.2025.101933
Amro K.F. Dyab , Agata N. Burska , Vesselin N. Paunov
The development of realistic 3D cell culture models by using emulsions and capillary suspensions based on aqueous two-phase systems (ATPS) has advanced the areas of cell physiology and biology. It has shown the potential to enhance the fields of cancer research, biotechnology, rapid testing of drug efficiency and toxicity, tissue engineering, as well as regenerative medicine. It has been increasingly accepted that 3D cells culture more closely reflects normal cellular function due to the enhanced cell interactions, which mimic the in vitro microenvironment and architecture of natural organs and tissues. In this review, we discuss the ATPS-aided methods to form 3D cell spheroids and cell networks by using colloids as templates for the purposes of cell structuring and will discuss the limitations and the advantages of these approaches. The use of ATPS-based cell spheroids has helped to advance basic cell sciences, including understanding cancer cell interactions with their environment in solid tumors, creating better drug models and studying cancer metastasis. Such multi-cellular assemblies have also been applied for engineering tissue constructs which have great potential for studying cell interactions in biological systems under a more realistic in vitro environment compared to 2D cell culture.
基于水两相体系(ATPS)的乳液和毛细悬浮液建立逼真的三维细胞培养模型,推动了细胞生理学和生物学领域的发展。它已经显示出在癌症研究、生物技术、药物效率和毒性的快速测试、组织工程以及再生医学等领域的潜力。由于细胞相互作用增强,3D细胞培养更能反映正常细胞功能,从而模拟体外微环境和自然器官和组织的结构,这一观点已被越来越多的人接受。在这篇综述中,我们讨论了atp辅助方法,以胶体为模板,形成三维细胞球体和细胞网络,以达到细胞结构的目的,并将讨论这些方法的局限性和优势。使用基于atp的细胞球体有助于推进基础细胞科学,包括了解实体肿瘤中癌细胞与环境的相互作用,创建更好的药物模型和研究癌症转移。这种多细胞组件也被应用于工程组织构建,与二维细胞培养相比,在更现实的体外环境下研究生物系统中细胞相互作用具有很大的潜力。
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引用次数: 0
Micro- and nanoplastics as transport vectors for organic contaminants in the environment: A critical review 微塑料和纳米塑料作为环境中有机污染物的运输载体:综述
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-06-06 DOI: 10.1016/j.cocis.2025.101934
Charlotte Henkel , Thorsten Hüffer , Snežana Maletić , Thilo Hofmann
The impact of micro- and nanosized plastic particles on the mobility of organic contaminants in the environment is a topic of ongoing scientific debate. Their extensive surface area and capacity to interact with organic contaminants have led to frequent concerns that micro- and nanoplastics significantly enhance their mobility and facilitate contaminant uptake by marine biota. For terrestrial systems, this hypothesis has been adopted, raising concerns that plastic particles could facilitate the transport of contaminants into deeper soil layers, thereby posing a threat to groundwater resources, especially in agricultural soils. These soils receive substantial plastic input through various sources, such as organic soil amendments, mulch, recycled wastewater, and atmospheric deposition. This review examines the molecular interactions between organic contaminants, including a wide range of non-intentionally added substances and additives, and plastic interfaces. We critically analyze the role of micro- and nanoplastics as vectors for contaminants in both marine environments and agricultural soils. Our analysis suggests that the vector effect of contaminants via micro- and nanoplastics in the marine environment is generally insignificant compared to other exposure routes. Our calculations regarding the mass transfer of common plastic additives indicate that the role of micro- and, particularly, nanoplastics as carriers for the majority of organic contaminants in agricultural soils is limited due to rapid desorption rates. Although micro- and nanoplastics do not considerably contribute to transport phenomena as vectors, it is crucial to recognize that they are significant sources of potentially harmful contaminants. These issues must be addressed in the forthcoming INC-5 plastic treaty.
微纳米塑料颗粒对环境中有机污染物迁移的影响一直是科学界争论的话题。微塑料和纳米塑料具有广泛的表面积和与有机污染物相互作用的能力,因此人们经常担心微塑料和纳米塑料会显著提高其流动性,并促进海洋生物对污染物的吸收。对于陆地系统,已经采用了这一假设,这引起了人们的关注,即塑料颗粒可能促进污染物进入更深的土层,从而对地下水资源构成威胁,特别是在农业土壤中。这些土壤通过各种来源获得大量的塑料输入,如有机土壤改良剂、地膜、回收废水和大气沉降。本文综述了有机污染物(包括各种非故意添加的物质和添加剂)与塑料界面之间的分子相互作用。我们批判性地分析了微塑料和纳米塑料作为海洋环境和农业土壤中污染物载体的作用。我们的分析表明,与其他暴露途径相比,海洋环境中通过微塑料和纳米塑料的污染物载体效应通常微不足道。我们对普通塑料添加剂的传质计算表明,由于解吸速度快,微塑料,特别是纳米塑料作为农业土壤中大多数有机污染物的载体的作用是有限的。尽管微塑料和纳米塑料作为载体对运输现象的贡献不大,但认识到它们是潜在有害污染物的重要来源是至关重要的。这些问题必须在即将举行的c -5塑料条约中加以解决。
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引用次数: 0
Pickering emulsions stabilized by cellulose nanofibers obtained from agricultural and food waste 由从农业和食物垃圾中获得的纤维素纳米纤维稳定的酸洗乳
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-05-27 DOI: 10.1016/j.cocis.2025.101931
Noriko Kanai , Izuru Kawamura
Cellulose nanofibers (CNFs) have been extensively studied as natural stabilizers and emulsifiers for oil-in-water Pickering emulsions (PEs). While wood has been the primary source of CNFs worldwide, agricultural and food waste (AFW) is an attractive biomass source due to its fast growth and abundance. AFW-derived CNFs share structural similarities with wood-derived CNFs, with comparable emulsifying properties, and have attracted significant attention in food and cosmetics industries. Importantly, developing PEs stabilized by AFW-derived CNFs creates new research opportunities for waste valorization and upcycling into sustainable materials. This review summarizes the latest research of PEs stabilized by AFW-derived CNFs and cellulose nanocrystals.
纤维素纳米纤维作为水包油皮克林乳状液的天然稳定剂和乳化剂得到了广泛的研究。虽然木材一直是世界范围内CNFs的主要来源,但由于其快速增长和丰富,农业和食物垃圾(AFW)是一个有吸引力的生物质来源。afw衍生的CNFs与木材衍生的CNFs具有结构上的相似性,具有相似的乳化性能,并且在食品和化妆品行业引起了极大的关注。重要的是,开发由afw衍生的CNFs稳定的PEs为废物增值和升级回收为可持续材料创造了新的研究机会。本文综述了afw衍生CNFs和纤维素纳米晶体稳定聚乙烯的最新研究进展。
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引用次数: 0
Confocal Raman spectroscopy applied to microemulsions and nanoemulsions 共聚焦拉曼光谱在微乳液和纳米乳液中的应用
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-05-24 DOI: 10.1016/j.cocis.2025.101932
Cintia J. Fernandez, Verónica Volpe, Analía Guerrero, Danielle Silva do Nascimento, Marcos Grünhut
Raman spectroscopy is a light scattering technique in which a molecule scatters incident light at different wavelengths depending on the chemical structure of the analyte, from a high-intensity laser light source. The Raman scattered light is detected to create the Raman spectrum, which is unique to the chemical compounds present in the sample, acting as chemical fingerprints. Since Raman spectrometers can be coupled to a confocal microscope, the selection of regions of interest and a high magnification of the image of the sample can be achieved. Furthermore, 2D and 3D mapping can be generated from thousands of Raman spectra acquired from different positions on the sample, showing the distribution of individual chemical components in the sample. This review summarizes recent advances in the application of confocal Raman spectroscopy to the physicochemical and analytical characterization of microemulsions and nanoemulsions, focusing primarily on topical formulations and biological studies (in-vitro and ex-vivo), and including representative in-vivo and clinical investigations. Identification, quantification, and distribution of components (surfactants, oil phase, active ingredients, etc.) in the colloidal systems, as well as to biological studies related to dynamic processes of formulations in different tissues, even in real-time, were performed. The methodological aspects of confocal Raman spectroscopy in recent works were adequately described, discussed, and compared. Also, we analyzed the limitations and advantages of the spectroscopic technique, including its contribution to green chemistry. Finally, we discuss future perspectives considering its combination with chemometric and artificial intelligence algorithms to improve the quality of the results.
拉曼光谱是一种光散射技术,其中分子散射来自高强度激光光源的不同波长的入射光,这取决于被分析物的化学结构。检测到的拉曼散射光产生了拉曼光谱,这是样品中存在的化合物所特有的,就像化学指纹一样。由于拉曼光谱仪可以耦合到共聚焦显微镜,感兴趣的区域的选择和样品的图像的高放大率可以实现。此外,从样品上不同位置获取的数千个拉曼光谱可以生成二维和三维映射,显示样品中单个化学成分的分布。本文综述了共聚焦拉曼光谱在微乳和纳米乳的理化和分析表征中的应用的最新进展,主要集中在局部配方和生物研究(体外和离体),包括有代表性的体内和临床研究。对胶体体系中的组分(表面活性剂、油相、活性成分等)进行鉴定、定量和分布,并对制剂在不同组织中的动态过程进行生物学研究,甚至进行实时研究。在最近的工作中,共聚焦拉曼光谱的方法学方面得到了充分的描述、讨论和比较。同时,分析了光谱学技术的局限性和优点,以及光谱学技术对绿色化学的贡献。最后,我们讨论了考虑其与化学计量学和人工智能算法相结合以提高结果质量的未来前景。
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引用次数: 0
Corrigendum to “Forces at superhydrophobic and superamphiphobic surfaces” [Curr Opin Colloid Interface Sci 47 (June 2020) 46–57] “超疏水和超两疏表面的作用力”的勘误表[Curr Opin胶体界面科学47 (June 2020) 46-57]
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-05-22 DOI: 10.1016/j.cocis.2025.101923
Mimmi Eriksson , Agne Swerin
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引用次数: 0
A review of recent trends in structuring oleogel-based emulsions for food applications 综述了食品用油凝胶基乳剂结构的最新趋势
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-05-14 DOI: 10.1016/j.cocis.2025.101924
Shahzad Farooq , Muhammad Ijaz Ahmad , Abdullah , Usman Ali , Hui Zhang
Oleogel emulsions, a hybrid system combining oleogelation and emulsification, have emerged as a groundbreaking innovation in colloidal science, providing sustainable and healthier alternatives for food formulation. In the broadest sense, oleogel emulsions can be structured by dispersing oleogels in water or vice versa, stabilized by interfacially adsorbed food-grade particles or entangled network structures that retard droplet–droplet coalescence and phase separation. This review aims to provide an up-to-date overview of various oil-structuring approaches, highlighting their properties, different types of oleogel-structured emulsions, and the stabilization mechanisms involved in the formation of oleogel emulsions. Specifically, the factors affecting the characteristics of oleogel emulsions are summarized, including oil types, oil/water ratios, oleogelators, emulsifiers, and processing parameters. Additionally, recent studies on the application of oleogel emulsions in food products are discussed. Currently, there are three main mechanisms responsible for stabilizing oleogel emulsions: Pickering particles, network stabilization, or a combination of both. The droplet size, physical stability, and rheological properties of oleogel emulsions are strongly influenced by the nature and concentration of the oleogelators used as they gel the oil phase, which helps achieve the desired thermomechanical and microstructural properties. Similarly, changes in the type of oils or oil/water ratios used directly impact the physicochemical properties of the systems. These structured emulsions have been widely used as fat substitutes in various food products such as ice cream, cakes, spreads, sausages, margarine, burgers, and peanut butters.
油凝胶乳液是一种结合了油凝胶和乳化的混合体系,已经成为胶体科学的突破性创新,为食品配方提供了可持续和更健康的替代品。从最广泛的意义上讲,油凝胶乳液可以通过将油凝胶分散在水中来构建,反之亦然,通过界面吸附的食品级颗粒或纠缠的网络结构来稳定,这些结构可以延缓液滴之间的聚结和相分离。本综述旨在提供各种油结构方法的最新概况,重点介绍了它们的性质,不同类型的油凝胶结构乳剂,以及形成油凝胶乳剂的稳定机制。具体而言,总结了影响油凝胶乳液特性的因素,包括油类型、油水比、油凝胶剂、乳化剂和工艺参数。此外,还讨论了近年来油凝胶乳剂在食品中的应用研究。目前,有三种主要机制负责稳定油凝胶乳液:Pickering颗粒,网络稳定,或两者的组合。油凝胶乳液的液滴大小、物理稳定性和流变性能在很大程度上受到油凝胶剂的性质和浓度的影响,这有助于实现所需的热机械和微观结构性能。同样,油的类型或油水比的变化也会直接影响体系的物理化学性质。这些结构乳剂已被广泛用作各种食品中的脂肪替代品,如冰淇淋、蛋糕、酱料、香肠、人造黄油、汉堡和花生酱。
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引用次数: 0
Recent advances in fluorine-free functionalized nanomaterials for low-wettability applications 低润湿性应用的无氟功能化纳米材料的最新进展
IF 7.9 2区 化学 Q1 CHEMISTRY, PHYSICAL Pub Date : 2025-04-26 DOI: 10.1016/j.cocis.2025.101922
Donald Hill, Henry Apsey, Shirin Alexander
The reduction in wettability afforded by applying superhydrophobic coatings onto substrate materials imbues many useful properties. This review presents recent research advancements of superhydrophobic surfaces formed from functionalised nanoparticles in some of their most promising applications. Silica and metal oxide nanoparticles can be readily functionalised with commercially available hydrophobic compounds to lower their surface energy and can be easily applied to materials with complicated forms and topographies using methods such as spraying or dipping, thus making the coating process adaptable to many situations. Advances in these coatings for imbuing icephobicity, corrosion resistance, self-cleaning, oil-in-water separation, and anti-biofouling behaviour are presented in this short review.
将超疏水涂层涂在基材上所带来的润湿性降低带来了许多有用的性能。本文综述了功能化纳米颗粒形成超疏水表面的最新研究进展及其最有前途的应用。二氧化硅和金属氧化物纳米颗粒可以很容易地与商业上可用的疏水性化合物功能化,以降低其表面能,并且可以很容易地使用喷涂或浸渍等方法应用于具有复杂形状和地形的材料,从而使涂层工艺适用于许多情况。本文简要介绍了这些涂层在渗透疏冰性、耐腐蚀性、自清洁性、油水分离性和抗生物污性等方面的研究进展。
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引用次数: 0
期刊
Current Opinion in Colloid & Interface Science
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