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Field test and sensitivity of Onchocerciasis rapid test in Ogun State, Nigeria 尼日利亚奥贡州盘尾丝虫病快速检测的现场试验和灵敏度
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.4
O. Surakat, S. Sam-Wobo, A. Golden, T. de Los Santos, M. Adeleke, D. Faulx, K. Ademolu, S. Bankole, M. Kalnoky, Eric Stevens, L. Yokobe
Objective: This study, conducted between March 2015 and July 2016, investigated the sensitivity and specificity of the OV-16 RDT and Dried Blood Spot (DBS) Enzyme-Linked Immunosorbent Assay (ELISA) for skin snip microfilaria (MF) detection in Ogun State. Methods: Five hundred and eighty-eight (588) members of 16 first-line communities in 8 endemic Local Government Areas (LGAs) provided fingerstick whole blood specimens examined for IgG4 antibodies against the O. volvulus antigen OV-16, using DBS OV-16 ELISA and OV-16 RDT. In consort with these specimens, 162 study participants consented to be evaluated by skin snip. Results: Results showed a seroprevalence of 106(18.0%) using ELISA and 102(17.3%) by RDT, with 92.2% agreement. The OV-16 RDT demonstrated a positive and negative agreement of 76.4 (95% CI 67.2 to 84.1%) and 95.6% (95% CI: 93.4 to 97.3), respectively, to the OV-16 ELISA results from the concordant dataset. Against the 64 positive skin snips microscopy results, sensitivity of the RDT was 79.7% (95% CI 73.43% to 85.27) and the ELISA was 70.3% (95% CI 64.72% to 75.37%). Conclusion: The results of this study provided information on the performance of the OV-16 RDT. This information will contribute data for comparison to studies in other areas where treatment is ongoing. In conclusion, the commercial launch of the OV-16 RDT has made available a point-of-care diagnostic tool that could serve to help local and country onchocerciasis elimination programs to measure changes and progress in onchocerciasis intervention.
目的:本研究于2015年3月至2016年7月在奥贡州进行OV-16 RDT和干血斑(DBS)酶联免疫吸附试验(ELISA)检测皮肤剪断微丝虫病(MF)的敏感性和特异性研究。方法:采用DBS OV-16 ELISA和OV-16 RDT检测方法,对8个疫区16个一线社区588例(588人)采集的弓形虫抗原OV-16 IgG4抗体进行手指全血检测。与这些标本相结合,162名研究参与者同意通过皮肤剪来评估。结果:ELISA检测血清阳性率为106例(18.0%),RDT检测血清阳性率为102例(17.3%),符合率为92.2%。OV-16 RDT与来自一致性数据集的OV-16 ELISA结果分别表现出76.4 (95% CI: 67.2至84.1%)和95.6% (95% CI: 93.4至97.3)的阳性和阴性一致性。对64例阳性皮肤剪镜检结果,RDT检测的灵敏度为79.7% (95% CI 73.43% ~ 85.27), ELISA检测的灵敏度为70.3% (95% CI 64.72% ~ 75.37%)。结论:本研究的结果为OV-16 RDT的性能提供了信息。这一信息将为正在进行治疗的其他领域的研究提供比较数据。总之,OV-16 RDT的商业化推出提供了一种即时诊断工具,可以帮助地方和国家的盘尾丝虫病消除规划衡量盘尾丝虫病干预措施的变化和进展。
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引用次数: 0
Gynaecological Pan-endoscopy (Hystero-laparoscopy) in a tertiary health facility in Nigeria: A ten-year clinical audit 尼日利亚一家三级卫生机构的妇科泛内窥镜(子宫-腹腔镜):一项为期十年的临床审计
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.1
A. Fehintola, S. Omitinde, M. Archibong, O. Ayegbusi, J.A. Abimbola, O. Loto
Objective: This study aims to determine the prevalence, indications, common findings, challenges, and complications of gynaecological pan-endoscopy in Obafemi Awolowo University Teaching Hospitals Complex, Osun State. Methods: It was a retrospective study. Records of patients who had gynaecological hysteroscopy and (or) Laparoscopy from 1st January 2012 to 31st December 2021 were retrieved, and relevant data were extracted and analyzed using the SPSS version 21.0 Results: There were 2125 gynaecological surgeries within the study period, with 207 endoscopies giving a prevalence of 9.7%. Infertility 100 (51.5%) was the most common indication. Common findings were tubal block 45(33.6%) and intrauterine adhesions 19 (31.7%). The most common complication and challenge were shoulder tip pain 35(18.0%) and instrument failure 76 (39.2%), respectively. There is a statistically significant relationship between the occurrence of complications during Endoscopy and duration of surgery (X2 = 25.693, P= 0.000), endoscopy type (X2=21.636, P=0.000), and hospital stay (X2 = 63.213, P=0.000) Conclusion: The utilization rate of gynaecological pan-endoscopy could be higher and shows more skills, logistics, and staffing. Therefore, efforts should be intensified towards training and provision of up-to-date facilities for endoscopic surgery in our setting.
目的:本研究旨在确定奥孙州奥巴菲米·阿沃洛沃大学教学医院综合楼妇科泛内窥镜的患病率、适应症、常见发现、挑战和并发症。方法:回顾性研究。检索2012年1月1日至2021年12月31日期间接受妇科宫腔镜和(或)腹腔镜检查的患者的记录,并使用SPSS 21.0版提取和分析相关数据。结果:研究期间共有2125例妇科手术,207例内镜检查的患病率为9.7%。不孕100(51.5%)是最常见的指征。常见的表现是输卵管阻塞45例(33.6%)和宫内粘连19例(31.7%)。最常见的并发症和挑战分别是肩尖疼痛35例(18.0%)和器械故障76例(39.2%)。内镜下并发症的发生率与手术时间(X2=25.693,P=0.000)、内镜类型(X2=21.636,P=0.0000)和住院时间(X2=63.213,P=0.000。因此,应加大力度,在我们的环境中培训和提供最新的内窥镜手术设施。
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引用次数: 0
Effect of psychoactive substance use on academic activities and performance among undergraduates of University of Lagos 精神活性物质使用对拉各斯大学本科生学习活动和成绩的影响
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.8
B. Osalusi, O. Koleowo, O. Ogunsemi, L. Ogunjimi, T. Afe, A. Ale, A. Agboola, M. Deji-Agboola
Background: The objective of this study was to assess the effect of psychoactive substance use on academic performance among university students of Lagos undergraduates. Methods: This is a descriptive cross-sectional study to assess psychoactive substance use and its relation to academic performance among undergraduate students of the University of Lagos. A multi-stage sampling technique was used to select the participants. Data was collected using a self-administered semi-structured questionnaire adapted from WHO model core questionnaire self-administered format. Data was collected and analyzed using the free-liscence software package Epi-Info, version 7.2.2.16. Chi square and Fisher's exact were used to test for any significant association between psychoactive substances use and academic performance of the respondents. Level of significance (p) was set at 0.05. Result. Prevalence of psychoactive substance use was 28.6%. Male and female respondents were270 (69.77%) and 117(30.23%) respectively, with age range between 14 and 30 and mean age of 20.51 (SD)(±2.91) year. Alcohol was the most abused substance with 68.99%, this was followed by cigarette with 20.67% ever use prevalence. The mean age of first use of psychoactive substance was 16.31±3.89. Using the Grade Point Average system from the previous semester, majority of the respondents (87.08%) had GPA >2.50. Both frequency of studying and mean CGPA was statistically better among non-life time users and non-current users of alcohol, tobacco and cannabis in the male group. However there was no statical significance among female group. Using fischer exact test to assess the effect of age of first substance use and mean CGPA. The age of first substance use was statistically significant for tobacco p = 0.007. Conclusion. Psychoactive substance use among students was common and negatively associated with students’ academic performance especially among male gender.
背景:本研究的目的是评估精神活性物质的使用对拉各斯大学生学习成绩的影响。方法:这是一项描述性的横断面研究,旨在评估拉各斯大学本科生中精神活性物质的使用及其与学习成绩的关系。采用多阶段抽样技术来选择参与者。数据采用自填半结构化问卷收集,该问卷改编自世界卫生组织模型核心问卷自填格式。使用免费的liscence软件包Epi Info(版本7.2.2.16)收集和分析数据。卡方检验和Fisher精确检验被调查者使用精神活性物质和学习成绩之间是否存在显著关联。显著性水平(p)设定为0.05。后果精神活性物质使用的患病率为28.6%。男性和女性受访者分别为270人(69.77%)和117人(30.23%),年龄在14至30岁之间,平均年龄为20.51(SD)(±2.91)岁。酒精是滥用最多的物质,占68.99%,其次是香烟,有史以来使用率为20.67%。首次使用精神活性物质的平均年龄为16.31±3.89岁。使用上学期的平均绩点系统,大多数受访者(87.08%)的GPA>2.50。在男性组中,非终身使用者和非当前酒精、烟草和大麻使用者的研究频率和平均CGPA在统计上都更好。但女性组间无统计学意义。使用fischer精确检验来评估首次使用药物的年龄和平均CGPA的影响。烟草首次使用物质的年龄具有统计学意义,p=0.007。结论学生中精神活性物质的使用很常见,并且与学生的学习成绩呈负相关,尤其是在男性中。
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引用次数: 0
Monkeypox related knowledge, attitudes and practices among students in a tertiary institution in southwest, Nigeria: A cross-sectional study 尼日利亚西南部某大专院校学生猴痘相关知识、态度和做法:一项横断面研究
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.3
A. Oyebade, A. Oshineye, A. Olarinmoye, O. Kayode, A. Akinpelu, M. Oladosu
Introduction: Monkeypox caused by monkeypox virus, a member of the Orthopoxvirus genus in the family Poxviridae is usually a self-limited disease, however severe cases can occur with case fatality ratio of 3–6% being reported in recent times. This study is aimed at assessing monkeypox related knowledge, attitudes and practices among students in a tertiary institution in Southwest, Nigeria. Methodology: The study utilized a cross-sectional design and semi-structured questionnaire to collect data from 278 respondents from August to October 2022. Results: In this study, only 37.8% of respondents had good monkeypox related knowledge, 87.8% had good monkeypox related attitude while 96% had good monkeypox related practices. There was association between good monkeypox related knowledge and university education level (p=0.002) with 100 Level student having better knowledge. There was also association between good monkeypox related attitude and sex (p=0.012) with female respondents having better attitudes and there was association between monkeypox related practices and age (p=0.028) with respondents between the ages of 18-22 years having better practices. However, there was no association between monkeypox related knowledge, attitudes and practices and marital status, ethnicity and religion. Conclusion: Our findings revealed the crucial need for public health education on monkeypox infection to improve knowledge in order to prevent and protect students from monkeypox infection. Good monkeypox related attitudes and practices should be maintained and improved through measures for reduction of exposure to the virus and prompt detection and response.
简介:猴痘病毒是痘病毒科正痘病毒属的一种病毒,由猴痘病毒引起的猴痘通常是一种自限性疾病,但近年来也有严重病例的报道,病死率为3-6%。本研究旨在评估尼日利亚西南部一所高等院校学生对猴痘的相关知识、态度和做法。研究方法:采用横断面设计和半结构化问卷,从2022年8月至10月收集了278名受访者的数据。结果:本研究中,仅有37.8%的受访者对猴痘有良好的相关知识,87.8%的受访者对猴痘有良好的相关态度,96%的受访者对猴痘有良好的相关行为。良好的猴痘相关知识与大学教育程度相关(p=0.002), 100级学生的猴痘相关知识较好。良好的猴痘相关态度与性别有关(p=0.012),女性应答者的态度较好;猴痘相关行为与年龄有关(p=0.028), 18-22岁应答者的行为较好。然而,与猴痘有关的知识、态度和做法与婚姻状况、种族和宗教之间没有关联。结论:开展猴痘公共卫生教育,提高对猴痘感染的认识,是预防和保护学生猴痘感染的必要措施。应通过采取措施减少接触病毒并及时发现和作出反应,保持和改进与猴痘有关的良好态度和做法。
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引用次数: 0
Risk factors for chronic kidney disease among adults in a tertiary hospital community in north-central, Nigeria. 尼日利亚中北部一家三级医院社区成年人患慢性肾病的危险因素。
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.9
I. Mbah, P. Eseigbe, O. David, E. D. Kabilis, M. Ihekaike
Background: The prevalence of chronic kidney disease (CKD) is on the increase globally with an attendant heavy disease burden and high morbidity and mortality from end-stage renal disease (ESRD). Data on the prevalence of risk factors for chronic kidney disease from sub-Saharan Africa are scanty, more so in the northern part of Nigeria. There are several risk factors for CKD which include, obesity, hypertension, diabetes mellitus and some nephrotoxic agents. Preventive strategy through early detection and treatment has been advocated for CKD especially in our own setting where majority of patients present late and cannot afford the cost of renal replacement therapy which again is not readily available. Method: This study was conducted among the staff of Bingham University Teaching Hospital (BHUTH), Jos, as part of a screening exercise during the World Kidney Day (WKD) program of 2021, to determine the prevalence of modifiable risk factors for CKD. Adult subjects of 18 years and above, who consented to the study were mobilized after a sensitization talk. The parameters assessed were demographics, body mass index, blood pressures, proteinuria, fasting plasma glucose and plasma creatinine. Glomerular filtration rate (GFR) was estimated using CKD-EPI Creatinine Equation 2021. Data were analyzed using SPSS version 25. The level of statistical significance was set at a p-value of < 0.05. Results: 150 adult volunteers participated in the study. The mean age of the participants was 43.3±11.32 years (18-71 years), with 61.3% being females and 38.7% were males. The frequency of the risk factors of CKD observed were obesity in 45 (30.0%) of the participants and diabetes mellitus found in 44 (29.3%) of the participants, Proteinuria and glycosuria were found in 49 (32.7%) and 9 (6.0%) of the participants respectively while a whopping 37 (24.7%) of the participants had haematuria. The number of participants found with estimated glomerular filtration rate (eGFR) of <60ml/min/1.73m2 were 55 (36.7%). There was an independent association between older age (p = 0.010), being widowed/divorced (p = 0.041), and having diabetes (p = 0.006) with an eGFR <60ml/min/1.73m2. Conclusion The prevalence of CKD risk factors in this study population was high. Therefore, there is the need for adequate and continuous sensitization and routine screening in our various clinics for early detection and early management by lifestyle and risk factor modification to halt or reduce the growing burden of CKD with its attendant morbidity and mortality in Nigeria.
背景:慢性肾脏病(CKD)的患病率在全球范围内呈上升趋势,伴随着严重的疾病负担以及终末期肾病(ESRD)的高发病率和死亡率。关于撒哈拉以南非洲慢性肾脏病危险因素患病率的数据很少,尼日利亚北部更是如此。CKD有几个危险因素,包括肥胖、高血压、糖尿病和一些肾毒性药物。通过早期发现和治疗CKD的预防策略已被提倡,尤其是在我们自己的环境中,大多数患者出现较晚,无法负担肾脏替代治疗的费用,而肾脏替代治疗又不容易获得。方法:这项研究是在乔斯宾厄姆大学教学医院(BHUTH)的工作人员中进行的,作为2021年世界肾脏日(WKD)计划筛查活动的一部分,以确定CKD可改变风险因素的患病率。同意本研究的18岁及以上的成年受试者在致敏谈话后被动员起来。评估的参数包括人口统计学、体重指数、血压、蛋白尿、空腹血糖和血肌酐。肾小球滤过率(GFR)使用CKD-EPI肌酸酐方程2021进行估算。使用SPSS 25版对数据进行分析。统计学显著性水平设定为p值<0.05。结果:150名成年志愿者参与了这项研究。参与者的平均年龄为43.3±11.32岁(18-71岁),其中61.3%为女性,38.7%为男性。观察到的CKD危险因素的频率为45名(30.0%)参与者肥胖,44名(29.3%)参与者糖尿病,49名(32.7%)和9名(6.0%)参与者分别出现蛋白尿和糖尿,而多达37名(24.7%)参与者出现血尿。估计肾小球滤过率(eGFR)<60ml/min/1.73m2的参与者人数为55人(36.7%)。年龄较大(p=0.010)、丧偶/离婚(p=0.041)和糖尿病(p=0.006)与eGFR<60ml/min/173m2之间存在独立关联。结论本研究人群CKD危险因素的患病率较高。因此,我们需要在各种诊所进行充分和持续的致敏和常规筛查,通过改变生活方式和风险因素进行早期发现和早期管理,以阻止或减轻尼日利亚日益增长的CKD负担及其伴随的发病率和死亡率。
{"title":"Risk factors for chronic kidney disease among adults in a tertiary hospital community in north-central, Nigeria.","authors":"I. Mbah, P. Eseigbe, O. David, E. D. Kabilis, M. Ihekaike","doi":"10.4314/rejhs.v11i3.9","DOIUrl":"https://doi.org/10.4314/rejhs.v11i3.9","url":null,"abstract":"Background: The prevalence of chronic kidney disease (CKD) is on the increase globally with an attendant heavy disease burden and high morbidity and mortality from end-stage renal disease (ESRD). Data on the prevalence of risk factors for chronic kidney disease from sub-Saharan Africa are scanty, more so in the northern part of Nigeria. There are several risk factors for CKD which include, obesity, hypertension, diabetes mellitus and some nephrotoxic agents. Preventive strategy through early detection and treatment has been advocated for CKD especially in our own setting where majority of patients present late and cannot afford the cost of renal replacement therapy which again is not readily available. \u0000Method: This study was conducted among the staff of Bingham University Teaching Hospital (BHUTH), Jos, as part of a screening exercise during the World Kidney Day (WKD) program of 2021, to determine the prevalence of modifiable risk factors for CKD. Adult subjects of 18 years and above, who consented to the study were mobilized after a sensitization talk. The parameters assessed were demographics, body mass index, blood pressures, proteinuria, fasting plasma glucose and plasma creatinine. Glomerular filtration rate (GFR) was estimated using CKD-EPI Creatinine Equation 2021. Data were analyzed using SPSS version 25. The level of statistical significance was set at a p-value of < 0.05. \u0000Results: 150 adult volunteers participated in the study. The mean age of the participants was 43.3±11.32 years (18-71 years), with 61.3% being females and 38.7% were males. The frequency of the risk factors of CKD observed were obesity in 45 (30.0%) of the participants and diabetes mellitus found in 44 (29.3%) of the participants, Proteinuria and glycosuria were found in 49 (32.7%) and 9 (6.0%) of the participants respectively while a whopping 37 (24.7%) of the participants had haematuria. The number of participants found with estimated glomerular filtration rate (eGFR) of <60ml/min/1.73m2 were 55 (36.7%). There was an independent association between older age (p = 0.010), being widowed/divorced (p = 0.041), and having diabetes (p = 0.006) with an eGFR <60ml/min/1.73m2. \u0000Conclusion The prevalence of CKD risk factors in this study population was high. Therefore, there is the need for adequate and continuous sensitization and routine screening in our various clinics for early detection and early management by lifestyle and risk factor modification to halt or reduce the growing burden of CKD with its attendant morbidity and mortality in Nigeria.","PeriodicalId":29646,"journal":{"name":"Research Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43004337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study of EEG findings among subjects in seizure-remission and patients with epilepsy in a resource constrained west African psychiatric hospital. 一项资源有限的西非精神病院癫痫缓解期受试者和癫痫患者脑电图结果的比较研究。
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.10
O. Aina, A. O. Owoeye, S. O. Oluwaniyi, I. Amoo
Background: Epilepsy is one of the commonest chronic neurological disorders, most especially in developing countries of the World. Again, electroencephalography (EEG) is an important investigation in epileptology and more so in monitoring seizure remission. Thus, in a resource constrained country like Nigeria, our study aimed to determine the epileptiform activities using routine EEG recordings on subjects in seizure remission compared to those subjects with active seizures. Methods: In our study, and following ethical approval, standard EEG recording was carried out on convenient samples of equal number (131) of subjects with active seizure and those in seizure remission using the “Neurofax” Electroencephalography, EEG-1200 (R) machine. The EEG machine was used to carry out an awake 22-channel EEG scalp recording on each subject. Results: Among subjects with active seizures, the mean duration of seizure was 2.80±2.44 years, with range of 0.5 to 12.0 years. For subjects in seizure remission (SSR), the mean duration of remission was 2.41±1.03 years, with range of 1 to 5 years. Out of the 131 subjects with seizure, 37 (28.3%) had normal EEG recording; and 94 (71.7%) had abnormal EEG recordings with various forms of epileptiform activities. On the other hand, of the 131 subjects in seizure remission (SSR), nearly half, 62 (47.3%) had normal EEG recording and 69(52.7%) had abnormal (epileptiform activities) recording. The difference in these EEG findings between the two study groups was significant with F=19.29, p=0.00*; t=-2.22, p=0.028*; and 95% Confidence Interval, CI=-0.70 to -0.40. Conclusion: In addition to clinical evaluation, routine EEG recording can be used to monitor seizure remission in resource constrained countries such as Nigeria.
背景:癫痫是最常见的慢性神经系统疾病之一,尤其是在世界发展中国家。同样,脑电图(EEG)是癫痫学的一项重要研究,在监测癫痫缓解方面更是如此。因此,在尼日利亚这样一个资源有限的国家,我们的研究旨在通过对癫痫缓解期受试者与活动性癫痫受试者的常规脑电图记录来确定癫痫样活动。方法:在我们的研究中,在获得伦理批准后,使用“Neurofax”脑电图EEG-1200(R)机对相同数量(131)的活动性癫痫发作受试者和癫痫缓解受试者的方便样本进行标准脑电图记录。脑电图机用于对每个受试者进行清醒的22通道脑电图头皮记录。结果:在活动性癫痫发作的受试者中,癫痫发作的平均持续时间为2.80±2.44年,范围为0.5至12.0年。发作缓解期(SSR)受试者的平均缓解期为2.41±1.03年,范围为1至5年。131例癫痫患者中,37例(28.3%)脑电图记录正常;94例(71.7%)有不同形式的癫痫样活动的异常脑电图记录。另一方面,在131名癫痫缓解(SSR)受试者中,近一半的受试者,62人(47.3%)的脑电图记录正常,69人(52.7%)的癫痫样活动记录异常。两个研究组的脑电图结果差异显著,F=19.29,p=0.00*;t=-2.22,p=0.028*;95%置信区间CI=-0.70至-0.40。结论:在尼日利亚等资源有限的国家,除了临床评估外,常规脑电图记录还可用于监测癫痫缓解情况。
{"title":"A comparative study of EEG findings among subjects in seizure-remission and patients with epilepsy in a resource constrained west African psychiatric hospital.","authors":"O. Aina, A. O. Owoeye, S. O. Oluwaniyi, I. Amoo","doi":"10.4314/rejhs.v11i3.10","DOIUrl":"https://doi.org/10.4314/rejhs.v11i3.10","url":null,"abstract":"Background: Epilepsy is one of the commonest chronic neurological disorders, most especially in developing countries of the World. Again, electroencephalography (EEG) is an important investigation in epileptology and more so in monitoring seizure remission. Thus, in a resource constrained country like Nigeria, our study aimed to determine the epileptiform activities using routine EEG recordings on subjects in seizure remission compared to those subjects with active seizures. \u0000Methods: In our study, and following ethical approval, standard EEG recording was carried out on convenient samples of equal number (131) of subjects with active seizure and those in seizure remission using the “Neurofax” Electroencephalography, EEG-1200 (R) machine. The EEG machine was used to carry out an awake 22-channel EEG scalp recording on each subject. \u0000Results: Among subjects with active seizures, the mean duration of seizure was 2.80±2.44 years, with range of 0.5 to 12.0 years. For subjects in seizure remission (SSR), the mean duration of remission was 2.41±1.03 years, with range of 1 to 5 years. Out of the 131 subjects with seizure, 37 (28.3%) had normal EEG recording; and 94 (71.7%) had abnormal EEG recordings with various forms of epileptiform activities. On the other hand, of the 131 subjects in seizure remission (SSR), nearly half, 62 (47.3%) had normal EEG recording and 69(52.7%) had abnormal (epileptiform activities) recording. The difference in these EEG findings between the two study groups was significant with F=19.29, p=0.00*; t=-2.22, \u0000p=0.028*; and 95% Confidence Interval, CI=-0.70 to -0.40. \u0000Conclusion: In addition to clinical evaluation, routine EEG recording can be used to monitor seizure remission in resource constrained countries such as Nigeria.","PeriodicalId":29646,"journal":{"name":"Research Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41485819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, attitudes and practices of disease prevention among health talk-giving healthcare workers in primary health centres at Osogbo 在奥索博初级保健中心进行保健讲座的保健工作者的疾病预防知识、态度和做法
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.5
Waliu Adesegun Tajudeen, K. Adesina, J.I. Fakorede, O. A. Muraina, B. Ikotun, H.J. Adesiyan, A. Olayinka, A. Omisore
Background: Disease prevention measures such as creating public awareness are needed to protect the vulnerable populace from acquiring diseases. Knowledgeable health care workers are pivotal to this, and it therefore becomes imperative to assess health workers in this regard. The objective of this study was to ascertain the level of knowledge, the kind of attitude towards and practices of disease prevention among health-talk giving primary health care workers in Osogbo, south western Nigeria. Methods: A descriptive cross-sectional study done among 204 respondents from 13 primary health care centres in Osogbo selected using multi-stage sampling technique. The research instrument used was a self-administered questionnaire analysed with SPSS 23.0. Univariate, bivariate, and multivariate analyses were done as appropriate and a p-value of <0.05 was taken as statistically significant. Results: The results of this study revealed that at least nine out of ten respondents had good knowledge (90.2%) and positive attitude (94.1%) towards disease prevention. A greater proportion of doctors (100%) had good knowledge of disease prevention compared to other health workers while nurses took the lead in having a positive attitude (97.4%). Respondents had varying responses in their practices towards disease prevention, but generally speaking, most respondents who had good knowledge and positive attitudes also exhibited good practices. The only identifiable predictor of respondent's knowledge was level of education, (p=0.024 OR=0.157). Conclusion: The fact that about a tenth of respondents had poor knowledge and about 5% had negative attitude towards disease prevention is a major cause for concern. Since health talk-giving health workers interact directly with the populace, the potentially huge negative effects that this minority can have cannot be underestimated. Therefore, there is a need for close-monitoring and regular review of the kind of information given to clients as well as training and re-training of health workers.
背景:需要采取疾病预防措施,如提高公众意识,以保护弱势群体免受疾病感染。知识渊博的卫生保健工作者对此至关重要,因此必须在这方面对卫生工作者进行评估。这项研究的目的是确定尼日利亚西南部Osogbo的初级卫生保健工作者的知识水平、对疾病预防的态度和做法。方法:采用多阶段抽样技术,对来自奥索博13个初级卫生保健中心的204名受访者进行了一项描述性横断面研究。研究工具为自填问卷,采用SPSS 23.0软件进行分析。酌情进行单因素、双因素和多因素分析,p值<0.05为有统计学意义。结果:调查结果显示,十分之九的受访者对疾病预防有良好的知识(90.2%)和积极的态度(94.1%)。与其他卫生工作者相比,医生(100%)具有良好的疾病预防知识的比例更高,而护士(97.4%)在积极态度方面处于领先地位。答复者对其疾病预防做法的反应各不相同,但一般而言,大多数具有良好知识和积极态度的答复者也表现出良好做法。唯一可识别的预测因子是受教育程度,(p=0.024 OR=0.157)。结论:约十分之一的受访者对疾病预防知识贫乏,约5%的受访者对疾病预防持消极态度,这是令人担忧的主要原因。由于提供卫生讲座的卫生工作者直接与民众互动,这一少数群体可能产生的巨大潜在负面影响不容低估。因此,有必要密切监测和定期审查向客户提供的信息种类,并对保健工作者进行培训和再培训。
{"title":"Knowledge, attitudes and practices of disease prevention among health talk-giving healthcare workers in primary health centres at Osogbo","authors":"Waliu Adesegun Tajudeen, K. Adesina, J.I. Fakorede, O. A. Muraina, B. Ikotun, H.J. Adesiyan, A. Olayinka, A. Omisore","doi":"10.4314/rejhs.v11i3.5","DOIUrl":"https://doi.org/10.4314/rejhs.v11i3.5","url":null,"abstract":"Background: Disease prevention measures such as creating public awareness are needed to protect the vulnerable populace from acquiring diseases. Knowledgeable health care workers are pivotal to this, and it therefore becomes imperative to assess health workers in this regard. The objective of this study was to ascertain the level of knowledge, the kind of attitude towards and practices of disease prevention among health-talk giving primary health care workers in Osogbo, south western Nigeria. \u0000Methods: A descriptive cross-sectional study done among 204 respondents from 13 primary health care centres in Osogbo selected using multi-stage sampling technique. The research instrument used was a self-administered questionnaire analysed with SPSS 23.0. Univariate, bivariate, and multivariate analyses were done as appropriate and a p-value of <0.05 was taken as statistically significant. \u0000Results: The results of this study revealed that at least nine out of ten respondents had good knowledge (90.2%) and positive attitude (94.1%) towards disease prevention. A greater proportion of doctors (100%) had good knowledge of disease prevention compared to other health workers while nurses took the lead in having a positive attitude (97.4%). Respondents had varying responses in their practices towards disease prevention, but generally speaking, most respondents who had good knowledge and positive attitudes also exhibited good practices. The only identifiable predictor of respondent's knowledge was level of education, (p=0.024 OR=0.157). \u0000Conclusion: The fact that about a tenth of respondents had poor knowledge and about 5% had negative attitude towards disease prevention is a major cause for concern. Since health talk-giving health workers interact directly with the populace, the potentially huge negative effects that this minority can have cannot be underestimated. Therefore, there is a need for close-monitoring and regular review of the kind of information given to clients as well as training and re-training of health workers.","PeriodicalId":29646,"journal":{"name":"Research Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42595200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relevance and challenges of neuroimaging for childhood tuberculous meningitis diagnosis in a resource-constraint country: A case report and literature review 在资源紧张的国家,神经影像学诊断儿童结核性脑膜炎的相关性和挑战:病例报告和文献综述
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.6
R. M. Ibraheem, S. O. Ariyibi, A. Gobir, A. R. Johnson, M. Yusuf, N. Adeleke
Objective: Tuberculous meningitis (TBM) may be an undiagnosed cause of childhood mortality or neurologic sequelae. Cranial computed tomography (CT) scan remains a relevant diagnostic and prognostic tool amidst negative cerebrospinal fluid or sputum findings for tuberculous meningitis (TBM) diagnosis. Delays in diagnosis and treatment increase morbidity in resource-constraint countries. Case report: A seven-year-old boy was referred with three weeks history of fever, progressive body weakness, aphasia and unconsciousness (three days). He had right cranial nerve III palsy, generalized hypertonia, and hyperreflexia in right lower limbs. All tuberculosis tests were negative except the cranial CT findings of leptomeningeal enhancement with basilar involvement and evidence of obstructive hydrocephalus. He was managed with anti-tuberculous drugs, prednisolone, ventriculoperitoneal shunt, and physiotherapy, and made a significant recovery after a year of anti-tuberculosis  treatment. Conclusion: The cranial CT scan findings facilitate TBM diagnosis for which prompt treatment commencement is crucial for a good outcome.
目的:结核性脑膜炎(TBM)可能是儿童死亡或神经系统后遗症的未确诊原因。颅脑计算机断层扫描(CT)仍然是诊断结核性脑膜炎(TBM)时脑脊液或痰液阴性的相关诊断和预后工具。在资源有限的国家,诊断和治疗延误会增加发病率。病例报告:一名七岁男孩因发热、进行性身体无力、失语和意识不清(三天)三周而入院。患者有右颅神经III型麻痹、全身强直、右下肢反射亢进。所有肺结核检查均为阴性,除了颅底受累的脑膜轻脑膜增强和阻塞性脑积水的证据。患者接受抗结核药物、强的松龙、脑室-腹膜分流术和物理治疗,经过一年的抗结核治疗后恢复明显。结论:颅脑CT表现有助于TBM的诊断,及时开始治疗是获得良好预后的关键。
{"title":"Relevance and challenges of neuroimaging for childhood tuberculous meningitis diagnosis in a resource-constraint country: A case report and literature review","authors":"R. M. Ibraheem, S. O. Ariyibi, A. Gobir, A. R. Johnson, M. Yusuf, N. Adeleke","doi":"10.4314/rejhs.v11i3.6","DOIUrl":"https://doi.org/10.4314/rejhs.v11i3.6","url":null,"abstract":"Objective: Tuberculous meningitis (TBM) may be an undiagnosed cause of childhood mortality or neurologic sequelae. Cranial computed tomography (CT) scan remains a relevant diagnostic and prognostic tool amidst negative cerebrospinal fluid or sputum findings for tuberculous meningitis (TBM) diagnosis. Delays in diagnosis and treatment increase morbidity in resource-constraint countries. \u0000Case report: A seven-year-old boy was referred with three weeks history of fever, progressive body weakness, aphasia and unconsciousness (three days). He had right cranial nerve III palsy, generalized hypertonia, and hyperreflexia in right lower limbs. All tuberculosis tests were negative except the cranial CT findings of leptomeningeal enhancement with basilar involvement and evidence of obstructive hydrocephalus. He was managed with anti-tuberculous drugs, prednisolone, ventriculoperitoneal shunt, and physiotherapy, and made a significant recovery after a year of anti-tuberculosis  treatment. \u0000Conclusion: The cranial CT scan findings facilitate TBM diagnosis for which prompt treatment commencement is crucial for a good outcome.","PeriodicalId":29646,"journal":{"name":"Research Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47951189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A correlation of 8-hour and 12-hour with 24-hour urinary protein among pregnant women with preeclampsia in a teaching hospital in South-Western Nigeria 尼日利亚西南部一家教学医院先兆子痫孕妇8小时和12小时尿蛋白与24小时尿蛋白的相关性
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.7
R. A. Akindele, S. O. Omopariola, A. Adeyemo, B. Afolabi, K. Awodele, E. O. Folami, A. Adeyemo
Background and Objective: Proteinuria is one of the cardinal features of preeclampsia, which is a common and potentially severe complication of pregnancy. This study sought to determine how the quantitative measurement of urine protein from 8-hour and 12- hour samples correlate with that of a 24-hour sample in diagnosing preeclampsia. Materials and Methods: 52 eligible pregnant women with preeclampsia were recruited between April 2017 and April 2018. For each patient, having emptied the bladder at 0 hour, urine was collected into three different containers (containers 1, 2, 3) at 8th hour, 12th hour and 24th hour ensuring that the bladder was emptied into each container at hours 8, 12 and 24. Volumes of 8 hours urine (volume in container 1), 12 hours urine (total volume in containers 1 and 2), and 24 hours urine (total volumes in containers 1, 2 and 3) were measured and 5 ml aliquot respectively obtained from each sample for colorimetric analysis of urinary protein. Data was analyzed using the EPI Info software Results: A total of 52 patients completed the study. The mean gestational age was 33+ 2.82weeks. The mean 8-hour, 12-hour and 24-hour urinary protein values were 2.1+1.53, 2.3+1.52 and 3.1+1.89 respectively. There were significant correlations between the protein values of 8-and 12-hour urine samples with those of 24-hour urine samples Conclusion: 8-hour and 12-hour values of urine protein correlated positively with values in 24-hour samples and may be useful for initial assessment of cases of preeclampsia for prompt interventions.
背景与目的:蛋白尿是先兆子痫的主要特征之一,先兆子痫是妊娠期常见且潜在的严重并发症。本研究试图确定8小时和12小时样本的尿蛋白定量测量与24小时样本的尿液蛋白定量测量在诊断先兆子痫中的相关性。材料和方法:在2017年4月至2018年4月期间,招募了52名符合条件的先兆子痫孕妇。对于在0小时排空膀胱的每个患者,在第8小时、第12小时和第24小时将尿液收集到三个不同的容器(容器1、2、3)中,确保在第8、12和24小时将膀胱排空到每个容器中。测量8小时尿液的体积(容器1中的体积)、12小时尿液的容量(容器1和2中的总体积)和24小时尿液的容积(容器1、2和3中的总容量),并分别从每个样品中获得5ml等分试样用于尿蛋白的比色分析。使用EPI信息软件对数据进行分析结果:共有52名患者完成了研究。平均胎龄33±2.82周,8小时、12小时和24小时尿蛋白平均值分别为2.1±1.53、2.3±1.52和3.1±1.89。8小时和12小时尿液样本的蛋白质值与24小时尿液样本中的蛋白质值之间存在显著相关性。
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引用次数: 0
Assessment of health-related quality of life and its determinants among patients with diabetic foot ulcer in Ilorin, Nigeria 尼日利亚伊洛林市糖尿病足溃疡患者健康相关生活质量及其决定因素评估
Pub Date : 2023-09-30 DOI: 10.4314/rejhs.v11i3.2
J. Olarinoye, A. Omotoso, A. Ogunmodede, C. Opeyemi, B. Olagbaye, N. Sanni, A. Aderibigbe
Background: The impact of foot ulceration on the psychosocial wellbeing of the Nigerian diabetic patients has not received enough attention. This study therefore attempted to evaluate the effect of diabetic foot ulcer on the quality of life of adults in a Nigerian diabetic population. Methodology: The impacts of diabetic foot ulcer (DFU) on the quality of life (QoL) of 104 adults living with diabetes were assessed using The Diabetes Foot Ulcer Scale and their determinants. Results: The mean QoL score was 42.25. Fifty-five (53.4%) had poor QoL status while 48 (46.6%) had good QoL. Determinants of poor QoL outcome include low socio-economic status (p = 0.017), lack of a tertiary education (p= 0.027), no diabetes-education (p = < 0.001), low socioeconomic status (p = 0.017), multiple ulcers (p = 0.022) and Wagner grade >3 ulcers (p = 0.004). Conclusion: Majority of patients with DFU in UITH, Nigeria have poor QoL and most of the predictors of poor QoL outcome are preventable and modifiable.
背景:足部溃疡对尼日利亚糖尿病患者心理健康的影响尚未得到足够的重视。因此,本研究试图评估糖尿病足溃疡对尼日利亚糖尿病人群成年人生活质量的影响。方法:使用糖尿病足溃疡量表及其决定因素评估糖尿病足溃疡(DFU)对104名糖尿病成年人生活质量(QoL)的影响。结果:平均生活质量评分为42.25。55人(53.4%)生活质量较差,48人(46.6%)生活质量良好。生活质量差的决定因素包括社会经济地位低(p=0.017)、缺乏高等教育(p=0.027)、没有糖尿病教育(p=0.001)、社会经济地位低下(p=0.017,尼日利亚生活质量差,生活质量差的大多数预测因素是可以预防和改变的。
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引用次数: 0
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Research Journal of Health Sciences
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