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Medication interruptions and associated factors among nurses working in pediatric unit at a selected referral hospital in Rwanda 卢旺达一家选定的转诊医院儿科护士的用药中断及其相关因素
Pub Date : 2021-12-13 DOI: 10.4314/rejhs.v9i4.1
A. Nkurunziza, G. Chironda, G. Katende, L. Rajeswaran, E. Munyaneza, Madeleine Mukeshim
Introduction: Interruptions have been proven to cause medication administration errors in pediatric settings. Therefore, this study assessed the medication interruptions and associated factors among nurses in a pediatric unit at a selected referral hospital in Rwanda. Methods: A descriptive observational study was conducted among 59 nurses using a developed observational checklist. Data were entered into SPSS, version 26. Descriptive and inferential statistics were used to analyze the data. The IRB of the University of Rwanda approved the study. Results: Among the 414 medication administrations observed, 149 (36%) had interruptions. The main source of interruption was technical problem (14.5%) with interruption from direct care (12%) as the main reason. The factors associated with interruption occurrence were shift of the day, time of medication round, duration and phase of medication administration and nurse perception (p = 0.001), age (p=0.046), educational level (p = 0.044) and professional experience (p = 0.031). Conclusion: The existence of medication interruptions is evident with associated factors predominantly being demographics and technical. Therefore, the authors recommended that an in-service training program for nurses regarding medication administration errors. The hospital leadership should address the technical problems including availing the required materials for medication administration.   French title: Interruptions médicamenteuses et facteurs associés chez les infirmières travaillant dans l'unité pédiatrique d'un hôpital de référence sélectionné au Rwanda Introduction : Il a été prouvé que les interruptions provoquent des erreurs d'administration de médicaments en milieu pédiatrique. Par conséquent, cette étude a évalué les interruptions de médication et les facteurs associés chez les infirmières d'une unité de pédiatrie d'un hôpital de référence sélectionné au Rwanda. Méthode de l'étude : Une étude observationnelle descriptive a été menée auprès de 59 infirmières à l'aide d'une liste de contrôle d'observation élaborée. Les données ont été saisies dans SPSS, 26. Des statistiques descriptives et inférentielles ont été utilisées pour analyser les données. L'IRB de l'Université du Rwanda a approuvé l'étude. Résultats de l'étude : Parmi les 414 administrations de médicaments observées, 149 (36 %) ont subi des interruptions. La principale source d'interruption était un problème technique (14,5 %) avec l'interruption des soins directs (12 %) comme principale raison. Les facteurs associés à l'occurrence d'interruption étaient décalage de la journée, heure de la tournée de médicaments, durée et phase d'administration des médicaments et perception de l'infirmière (p = 0,001), âge (p=0,046), niveau d'éducation (p = 0,044) et expérience professionnelle (p = 0,031). Conclusion : L'existence d'interruptions de médication est évidente avec des facteurs associés principalement démographiques et techniques. Par conséquent, les aute
导言:中断已被证明会导致儿科环境中的用药错误。因此,本研究评估了卢旺达选定转诊医院儿科护士的药物中断和相关因素。方法:使用开发的观察检查表对59名护士进行了描述性观察研究。数据输入SPSS版本26。描述性和推理统计用于分析数据。卢旺达大学IRB批准了这项研究。结果:在观察到的414次用药中,149次(36%)中断。中断的主要来源是技术问题(14.5%),直接护理中断(12%)是主要原因。与中断发生相关的因素是一天的变化、用药周期的时间、用药的持续时间和阶段以及护士的感知(p=0.001)、年龄(p=1.046)、教育水平(p=2.044)和专业经验(p=3.031)。结论:药物中断的存在与主要是人口和技术因素相关。因此,作者建议为护士制定一项关于药物管理错误的在职培训计划。医院领导层应解决技术问题,包括提供药物管理所需的材料。英文标题:卢旺达一家选定转诊医院儿科病房护士的药物中断和相关因素简介:中断已被证明会导致儿科环境中的药物错误。因此,本研究评估了卢旺达选定转诊医院儿科病房护士的药物中断和相关因素。研究方法:使用详细的观察检查表,对59名护士进行了描述性观察研究。数据输入SPSS,26。描述性和推理统计用于分析数据。卢旺达大学IRB批准了这项研究。研究结果:在414次观察到的药物给药中,149次(36%)中断。中断的主要原因是技术问题(14.5%),直接护理中断(12%)是主要原因。与中断发生相关的因素包括:日移、用药时间、用药时间和阶段以及护士的感知(p=0.001)、年龄(p=1.046)、教育水平(p=2.044)和工作经验(p=3.031)。结论:药物中断的存在明显,主要与人口统计学和技术相关因素有关。因此,作者建议对护士进行关于用药错误的继续教育计划。医院管理层应解决技术问题,包括提供给药所需的材料。
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引用次数: 0
High level of perceived stress among essential workers during the COVID 19 lockdown in a Nigerian state 尼日利亚一个州在COVID - 19封锁期间,基本工作人员感受到的压力很大
Pub Date : 2021-12-13 DOI: 10.4314/rejhs.v9i4.3
J. Falade, A. M. Oshatimi, A. Oyebanji, A. Babatola, J. Fadare, O. Olatunya, O. O. Falade
Background: COVID-19 pandemic caused unexpected socio-economic changes globally. This study determined the prevalence and factors associated with perceived stress among essential workers during the COVID-19 lockdown in Ekiti State, Nigeria.Method: A cross-sectional descriptive study that involved 588 essential workers in Ekiti State, Nigeria during the COVID-19 lockdown. The Perceived Stress Scale was used in the study Chi-square test of statistical significance and multivariate analysis using binary logistic regression were used in the analysis and the level of statistical significance was determined by a p-value of <0.05.Results: The prevalence of high perceived stress levels among all the respondents, health workers, and non-health workers were 64.1% (63.3-70.6), while health workers and non-health workers had a prevalence of 70.1% (65.5 -73.3) and 56.5% (23.5-38.7) respectively. The majority of the respondents related their sources of stress to inadequate transportation (63.3%), hearing of COVID related news (47.4%), and lack of finance (55.1%). Using Logistic Regression respondent respondents who were not satisfied with the support they received from the government during the pandemic had three fold high stress levels than respondents who were satisfied with the support received from the government [AOR= 3.228, (CI= 1.771- 5.886)]. Furthermore, the odd of the high stress level was one fold increased among male respondents than female respondents [AOR = 1.08 CI= (1.410-6.215). Conclusion: Stress management is recommended given the high-stress level among essential workers.   French title: Niveau de stress perçu chez les travailleurs essentiels pendant le casanier du COVID-19 dans l'état d'Ekiti, au Nigéria Contexte général de l'étude : La pandémie de COVID-19 a provoqué des changements socio-économiques inattendus dans le monde. Cette étude a déterminé la prévalence et les facteurs liés au stress perçu à un niveau parmi les travailleurs essentiels pendant la période de confinement du COVID-19 dans l'état d'Ekiti, au Nigéria.Méthode de l'étude : Une étude descriptive transversale qui a impliqué 588 travailleurs essentiels dans l'état d'Ekiti, au Nigéria, dans le cadre du confinement COVID-19. L'échelle de stress perçu a été utilisée dans le test du Chi carré de l'étude et une analyse multi variée a été utilisée. Le niveau statistiquement significatif a été déterminé par une valeur p < 0,05.Résultats de l'étude: Le total des répondants non-agents de santé et agents de santé présentait une prévalence de niveaux élevés de stress perçu de 64,1% (63,3-70,6), 56,5% (23,5-38,7) et 70,1% (65,5 - 73,3). La majorité des répondants ont lié leurs sources de stress à un transport inadéquat (63,3 %), à l'audition de nouvelles liées à COVID (47,4 %) et au manque de financement (55,1 %) En utilisant la régression logistique, les répondants qui étaient insatisfaits du soutien gouvernemental pendant la pandémie avaient des niveaux de stress trois fois plus é
背景:COVID-19大流行导致全球意外的社会经济变化。本研究确定了尼日利亚埃基蒂州COVID-19封锁期间基本工人的患病率和与感知压力相关的因素。方法:一项跨部门描述性研究,涉及尼日利亚埃基蒂州新冠封锁期间588名基本工人。在分析中使用了二元逻辑回归的统计显著性和多元分析的卡方检验中使用了感知应力量表,统计显著性水平由p值<0.05确定。结果:所有响应者、健康工作者和非健康工作者中高感知应力水平的患病率为64.1%(63.3-70.6),健康工作者和非健康工作者的患病率分别为70.1%(65.5-73.3)和56.5%(23.5-38.7)。大多数受访者将其压力源与交通不足(63.3%)、听到新冠相关新闻(47.4%)和缺乏资金(55.1%)联系起来。在大流行期间,对政府支持不满意的受访者比对政府支持感到满意的人有三倍的高压力水平[AOR=3.228,(CI=1.771-5.886)]。高压力水平的优势在男性受访者中比女性受访者增加了一倍[AOR=1.08 Ci=(1.410-6.215)结论:建议基本工人进行高水平的压力管理。英文标题:尼日利亚埃基蒂州新冠疫情期间关键工人的感知压力水平研究背景:新冠大流行在世界各地引发了意想不到的社会经济变化。本研究确定了尼日利亚埃基蒂州新冠疫情遏制期间关键工人中感知压力的患病率和相关因素。研究方法:一项横断面描述性研究,涉及尼日利亚埃基蒂州588名关键工人,作为新冠疫情遏制的一部分。在研究的卡方检验中使用了感知应力量表,并使用了多元分析。统计显著性水平由p值<0.05确定。研究结果:非卫生工作者和卫生工作者受访者的高感知压力水平患病率分别为64.1%(63.3-70.6)、56.5%(23.5-38.7)和70.1%(65.5-73.3)。大多数受访者将其压力源与交通不足(63.3%)、听到新冠相关新闻(47.4%)和缺乏资金(55.1%)联系起来。使用逻辑回归,在大流行期间对政府支持不满意的受访者的压力水平是对政府支持不满的受访者的三倍[AOR=3.228,(CI=1.771-5.886)]。受访男性高压力水平的奇数是女性的一倍[AOR=1.08 CI=(1410-6215)。结论:鉴于关键工人的高压力水平,建议进行压力管理。
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引用次数: 0
Review of the demographic pattern and outcomes of acute chemical poisoning in patients in a tertiary hospital in South-western Nigeria 审查尼日利亚西南部某三级医院患者急性化学中毒的人口统计模式和结果
Pub Date : 2021-12-13 DOI: 10.4314/rejhs.v9i4.4
O. Adejumo, S. S. Owolade, O. Lawal, O. Junaid, O. Egbi, A. Enikuomehin, B.A Umufo
Introduction: Acute chemical poisoning is a public health problem especially in developing countries where there is unrestricted access to chemical products, underreporting and absence of poisoning registers. Despite its importance, there is limited information on acute poisoning among adult population in Nigeria. The study was aimed at determining the demographic pattern and short term outcomes of acute chemical poisoning in patients in a tertiary health institution in South-western Nigeria over a 2 year period.Methodology: Records of cases of acute chemical poisoning over a 2-year period were retrieved and the following information extracted: socio-demographic data of patient, type of substance ingested, type of poisoning, reason for poisoning, intervention, and outcome of treatment. Results:There were 58 patients with a M:F ratio of 1:1.1. The mean age was 28.53±13.47 years. The most commonly ingested chemical was organophosphate seen in 31(53.4%). Poisoning was deliberate in 43 (74.1%); 36 patients (62.1%) had atropine; 16 patients (27.6%) had gastric lavage; one patient (1.7%) was dialyzed and 2 patients (3.4%) were admitted into ICU. Mortality rate was 8.6%. Conclusion: Deliberate acute chemical poisoning was common in young adults. Organophosphate is the most commonly ingested chemical. Government should enforce laws that that would restrict access to potentially harmful chemicals. French title: Schéma et résultats à court terme d'une intoxication chimique aiguë dans un hôpital tertiaire du sud-ouest du Nigéria Introduction : Les intoxications chimiques aiguës sont un problème de santé publique en particulier dans les pays en développement où il existe un accès illimité aux produits chimiques, une sous-déclaration et l'absence de registres des intoxications. Malgré son importance, il existe peu d'informations sur les intoxications aiguës parmi la population adulte au Nigéria.Objectif de l'étude: Déterminer le schéma démographique et les résultats à court terme des intoxications chimiques aiguës chez les patients d'un établissement de santé tertiaire du sud-ouest du Nigéria sur une période de 2 ans.Méthode de l'étude : Des dossiers de cas d'intoxication chimique aiguë sur une période de 2 ans ont été récupérés et les informations suivantes extraites : données sociodémographiques du patient, type de substance ingérée, type d'intoxication, raison de l'intoxication, intervention et résultat du traitement.Résultat de l'étude : Il y avait 58 patients avec un rapport M : F de 1:1,1. L'âge moyen était de 28,53 ± 13,47 ans. Le produit chimique le plus couramment ingéré était l'organophosphate vuswzsw3 dans 31 (53,4 %). L'empoisonnement était délibéré dans 43 (74,1 %); 36 patients (62,1%) avaient de l'atropine ; 16 patients (27,6 %) ont eu un lavage gastrique ; un patient (1,7%) a été dialysé et 2 patients (3,4%) ont été admis en réanimation. Le taux de mortalité était de 8,6%. Conclusion : Les intoxications chimiques aiguës délibérées étaient fré
导言:急性化学品中毒是一个公共卫生问题,特别是在发展中国家,在这些国家,化学品的获取不受限制,报告不足,缺乏中毒登记。尽管如此,关于尼日利亚成年人急性中毒的信息有限。该研究旨在确定尼日利亚西南部一所三级卫生机构2年期间急性化学中毒患者的人口模式和短期结果。检索了2年期间急性化学中毒病例的记录,并提取了以下信息:患者的社会人口统计数据、摄入的物质类型、中毒类型、中毒原因、干预和治疗结果。结果:58名患者的M:F比为1:1.1。平均年龄为28.53±13.47岁。最常见的摄入化学品是有机磷酸盐,31例(53.4%)。36名患者(62.1%)服用阿托品;16名患者(27.6%)接受洗胃;1名患者(1.7%)接受透析,2名患者(3.4%)进入ICU。死亡率为8.6%。结论:轻度急性化学中毒在年轻人中很常见。有机磷酸盐是最常用的化学品。政府应执行限制获得潜在有害化学品的法律。英文标题:尼日利亚西南部一家三级医院急性化学中毒的模式和短期结果简介:急性化学中毒是一个公共卫生问题,特别是在发展中国家,在这些国家,化学品的获取不受限制,报告不足,缺乏中毒记录。尽管其重要性,关于尼日利亚成年人急性化学中毒的信息很少。研究目的:确定尼日利亚西南部一家三级卫生设施患者在2年期间急性化学中毒的人口结构和短期结果。研究方法:检索2年期间的急性化学中毒病例记录,并提取以下信息::患者的社会人口统计数据、摄入的物质类型、中毒类型、中毒原因、干预和治疗结果。研究结果:58名患者的M:F比为1:1.1。平均年龄为28.53±13.47岁。31人(53.4%)最常摄入的化学物质是有机磷酸盐VUSWZSW3。43人(74.1%)故意中毒;36名患者(62.1%)服用阿托品。16名患者(27.6%)接受洗胃;1名患者(1.7%)接受透析,2名患者(3.4%)进入重症监护室。死亡率为8.6%。结论:故意急性化学中毒在年轻人中很常见。有机磷酸盐是最常用的化学物质。政府应执行限制获得潜在有害化学品的法律。
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引用次数: 0
Collaborative governance: The antidote for effective implementation of malaria elimination programme in Nigeria 协作治理:尼日利亚有效实施消除疟疾规划的解毒剂
Pub Date : 2021-12-13 DOI: 10.4314/rejhs.v9i4.7
B. A. Taleat, K. W. Olawoyin
Objective: The study examined the way inter-governmental collaboration can be improved to enhance malaria elimination programme in Southwestern Nigeria. Methodology: Primary data were collected through the administration of questionnaire and conduct of interviews. The study population comprised all categories of staff in the National Malaria Elimination Programme; staffs of Malaria Elimination Programme in three states and nine Local Governments in Southwestern Nigeria. A sample size of 388 respondents was selected for questionnaire administration from the study population. Interviews were conducted to complement information collected through questionnaire. Data collected were analysed using appropriate statistical methods. Results: The study revealed that increased allocation of funds; establishment of several anti-malaria programmes at all levels of government and integrated decision making were ways collaborative governance can be improved to enhance malaria elimination programme in the study area. Conclusion: The study concluded that collaborative governance is a sine qua non to the effective implementation of government programmes.
目的:本研究探讨了如何改善政府间合作,以加强尼日利亚西南部的疟疾消除规划。方法:通过问卷调查和访谈的方式收集第一手资料。研究对象包括国家消除疟疾方案的所有类别的工作人员;尼日利亚西南部3个州和9个地方政府消除疟疾规划的工作人员。从研究人群中选取388名受访者进行问卷调查。通过访谈来补充通过问卷收集到的信息。使用适当的统计方法对收集的数据进行分析。结果:研究表明,资金分配增加;在各级政府建立若干抗疟疾规划和综合决策是改进协作治理以加强研究领域消除疟疾规划的方法。结论:该研究得出结论,协作治理是有效实施政府计划的必要条件。
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引用次数: 1
Hydrogen peroxide measurements: its wet deposition in Higashi-Hiroshima city, concentration in Kurose River and role towards hydroxyl radical formation 过氧化氢测量:其在东广岛市的湿沉积、在黑森河的浓度以及对羟基自由基形成的作用
Pub Date : 2021-12-13 DOI: 10.4314/rejhs.v9i4.8
A. J. Anifowose, O. Olabode, I.S. Adedotun, H. Sakugawa
No Abstract.
没有摘要。
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引用次数: 0
Male participation in family planning: An untapped potential for increasing utilization of family planning services in Ondo, Southwestern Nigeria 男性参与计划生育:尼日利亚西南部翁多增加计划生育服务利用率的未开发潜力
Pub Date : 2021-12-13 DOI: 10.4314/rejhs.v9i4.2
R. O. Akande, O. Israel, A. Adefemi, E.O.K Leramo
Background: Men play crucial roles in the utilization of family planning services hence, ensuring their commitment to these services is essential for increasing family planning uptake. This study therefore, assessed the level of male participation in family planning services utilization and its associated factors in Ondo west LGA, Ondo State, Nigeria. Methods: The study utilized a community-based cross-sectional design. Multi-stage sampling technique was used to select 433 eligible respondents. Quantitative data were collected using semi-structured questionnaires and analyzed using IBM SPSS version 23; bivariate and multivariate analyses were done using Chi-square and binary logistic regression respectively at 5% level of significance.Results: 55% and 48.5% of the study participants, had poor knowledge and perception about family planning services respectively. At bivariate level, there were statistically significant associations between age (p = 0.046), number of children (p < 0.001), level of education (p = 0.023), and the utilization of FP services by the respondents. Conclusion: The knowledge of the respondents about FP services was poor and if unaddressed, could infringe upon the rights of their spouses to access such services. Increasing male participation may require targeting married men for educational interventions.   French title: Participation des hommes à la planification familiale : un potentiel  inexploité pour accroître l'utilisation des services de planification familiale à Ondo, dans le sud-ouest du Nigéria Contexte général de l'étude : Les hommes jouent un rôle important dans l'utilisation des services de planification familiale, par conséquent, obtenir leur engagement envers ces services est essentiel pour augmenter l'adoption de la planification familiale. Par conséquent, cette étude a évalué le niveau de participation des hommes dans l'utilisation des services de planification familiale et ses facteurs associés à Ondo West, Ondo State, Nigéria.Méthode de l'étude : Une étude transversale communautaire, les répondants étant des hommes mariés. Une technique d'échantillonnage à plusieurs degrés a été utilisée pour sélectionner 433 répondants admissibles. Les données ont été recueillies à l'aide de questionnaires semi-structurés. Les données ont été analysées à l'aide d'IBM SPSS version 23 ; des analyses bi variées et multi variées ont été effectuées en utilisant respectivement une régression logistique du chi carré et binaire à un niveau de signification de 5%.Résultat de l'étude : Environ 55 % et 48,5 % des participants à l'étude avaient respectivement une connaissance et une perception médiocres des services de planification familiale. Au niveau bi varié, il y avait des associations statistiquement significatives entre l'âge (p = 0,046), le nombre d'enfants (p < 0,001), le niveau d'éducation (p = 0,023) et l'utilisation des services de PF par les répondants.Conclusion : La connaissance des répondants sur les services de PF
背景:男子在利用计划生育服务方面发挥关键作用,确保他们对这些服务的承诺对于增加计划生育的接受至关重要。因此,本研究评估了尼日利亚昂多州昂多西部LGA男性参与计划生育服务利用率及其相关因素的水平。方法:本研究采用基于社区的跨部门设计。多级采样技术用于选择433名合格响应者。使用半结构化问卷收集定量数据,并使用IBM SPSS版本23进行分析。双变量和多元分析分别在5%显著性水平上使用卡方和二进制逻辑回归进行。结果:55%和48.5%的研究参与者对计划生育服务的知识和看法较差。在双变量水平上,年龄(p=0.046)、儿童数量(p<0.001)、教育水平(p=1.023)和受访者使用FP服务之间存在统计显著关联。结论:受访者对FP服务的了解很差,如果不提供,可能会侵犯其配偶获得此类服务的权利。增加男性参与可能需要针对已婚男性进行教育干预。英文标题:男性参与计划生育:尼日利亚西南部昂多增加计划生育服务使用的未开发潜力研究背景:男性在计划生育服务的使用中发挥着重要作用,因此,获得他们对这些服务的承诺对于增加计划生育的采用至关重要。因此,本研究评估了尼日利亚昂多州昂多西部男性参与计划生育服务的程度及其相关因素。研究方法:一项基于社区的横断面研究,受访者为已婚男性。采用多级抽样技术选择433名合格受访者。数据通过半结构化问卷收集。使用IBM SPSS版本23分析数据;双变量和多变量分析分别使用逻辑卡方回归和二元回归进行,显著性水平为5%。研究结果:约55%和48.5%的研究参与者分别对计划生育服务的知识和认知较差。在不同的BI水平上,年龄(p=0.046)、子女数量(p<0.001)、教育水平(p=1.023)和受访者对FP服务的使用之间存在统计显著关联。结论:受访者对FP服务了解程度较低,如果不加以考虑,可能会影响其配偶获得此类服务的权利。增加男性参与可能需要针对已婚男性进行教育干预。
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引用次数: 1
Abnormal biochemical parameters among term neonates with perinatal asphyxia and their non-asphyxiated controls in Osogbo 奥索博围产期窒息足月新生儿及其非窒息对照组生化指标异常
Pub Date : 2021-07-07 DOI: 10.4314/REJHS.V9I3.12
O. Kayode, O. Adebami, O. Oyedeji, S. Oninla, S. B. Oseni, A. Odeyemi
Objective: This study aimed to determine the prevalence of abnormal biochemical parameters among neonates with perinatal asphyxia in comparison to their non-asphyxiated controls.Methodology: This is a prospective case - control study involving 54 asphyxiated term neonates and 54 non-asphyxiated term babies at LAUTECH teaching hospital, Osogbo. Serum levels of Sodium, Bicarbonate, Chloride, Calcium and Potassium were determined daily for 72 hours in both groups using standard methods. The results were compared.Results: The overall prevalence of abnormal biochemical parameters namely hyponatraemia, hypocalcaemia, metabolic acidosis, hypochloraemia and hypokalaemia among the asphyxiated versus non-asphyxiated babies in the first 72 hours of life were 30.9% vs 19.8% (p < 0.020); 28.4% vs 4.9% (p < 0.000); 30.9% vs 3.1% (p < 0.0001); 27.2% vs 25.9% (p < 0.200) and 24.7% vs 3.1% (p < 0.070) respectively.Conclusion: Babies with hypoxic ischaemic encephalopathy stage III significantly showed the worst biochemical parameters; early estimation of serum electrolytes in neonates with perinatal asphyxia may be appropriate for timely intervention.  
目的:本研究旨在确定围生期窒息新生儿与非窒息对照组的生化参数异常发生率。方法:这是一项前瞻性病例对照研究,涉及54名窒息足月新生儿和54名非窒息足月婴儿,奥索博LAUTECH教学医院。两组患者采用标准方法,连续72小时每天测定血清钠、碳酸氢盐、氯化物、钙和钾的水平。对结果进行比较。结果:窒息儿与非窒息儿在出生后72小时内低钠血症、低钙血症、代谢性酸中毒、低氯血症、低钾血症等生化指标异常总体患病率分别为30.9%和19.8% (p < 0.020);28.4% vs 4.9% (p < 0.000);30.9% vs 3.1% (p < 0.0001);27.2% vs 25.9% (p < 0.200), 24.7% vs 3.1% (p < 0.070)。结论:缺氧缺血性脑病ⅲ期患儿生化指标最差;早期估计围产期窒息新生儿的血清电解质可能适合及时干预。
{"title":"Abnormal biochemical parameters among term neonates with perinatal asphyxia and their non-asphyxiated controls in Osogbo","authors":"O. Kayode, O. Adebami, O. Oyedeji, S. Oninla, S. B. Oseni, A. Odeyemi","doi":"10.4314/REJHS.V9I3.12","DOIUrl":"https://doi.org/10.4314/REJHS.V9I3.12","url":null,"abstract":"Objective: This study aimed to determine the prevalence of abnormal biochemical parameters among neonates with perinatal asphyxia in comparison to their non-asphyxiated controls.Methodology: This is a prospective case - control study involving 54 asphyxiated term neonates and 54 non-asphyxiated term babies at LAUTECH teaching hospital, Osogbo. Serum levels of Sodium, Bicarbonate, Chloride, Calcium and Potassium were determined daily for 72 hours in both groups using standard methods. The results were compared.Results: The overall prevalence of abnormal biochemical parameters namely hyponatraemia, hypocalcaemia, metabolic acidosis, hypochloraemia and hypokalaemia among the asphyxiated versus non-asphyxiated babies in the first 72 hours of life were 30.9% vs 19.8% (p < 0.020); 28.4% vs 4.9% (p < 0.000); 30.9% vs 3.1% (p < 0.0001); 27.2% vs 25.9% (p < 0.200) and 24.7% vs 3.1% (p < 0.070) respectively.Conclusion: Babies with hypoxic ischaemic encephalopathy stage III significantly showed the worst biochemical parameters; early estimation of serum electrolytes in neonates with perinatal asphyxia may be appropriate for timely intervention. \u0000 ","PeriodicalId":29646,"journal":{"name":"Research Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48990140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of patients with acute heart failure in North Central Nigeria 尼日利亚中北部急性心力衰竭患者的特征
Pub Date : 2021-07-07 DOI: 10.4314/REJHS.V9I3.3
J. Ogunmodede, P. Kolo, M. O. Bojuwoye, B. Dele-Ojo, A. J. Ogunmodede, A. Omotoso
Objectives: Heart failure (HF) is an important cause of hospital admission in Nigeria. HF is increasingly prevalent because the population is aging and HF epidemiology is changing. We aimed at profiling the socio-demographic, clinical and echocardiographic (Echo)  characteristics of patients admitted for acute HF. This is one of the largest cohorts of HF patients profiled in Nigeria so far. Methods: Cross sectional design. Socio-demographic, clinical and Echo data were collected from 455 patients admitted for AHF at University of Ilorin Teaching Hospital, North central, Nigeria. Results: Mean age of patients was 58.9± 15.7years, (men were older than women, P= 0.006). 265(58.2%) were males, most patients were aged >60 years, 4.8% had pre-existing Type2 Diabetes mellitus. 53.2% of patients presented in New York Heart Association Stages III and IV. Median duration of admission was 11days (IQR, 6-17), intrahospital mortality- 11.6%. Hypertension was the commonest aetiological factor (62.4%), followed by dilated cardiomyopathy 17.6%, rheumatic heart disease (6.6%), Peripartum cardiomyopathy (5.3%), and others. Conclusion: AHF patients in our study are older than those in previous studies in Nigeria and sub-Saharan Africa. Hypertension is main driver of AHF, and patients largely present with clinically advanced disease necessitating stronger public health education about risk factors and early presentation.  
目的:心力衰竭(HF)是尼日利亚住院的重要原因。由于人口老龄化和HF流行病学的变化,HF越来越普遍。我们旨在分析因急性心衰入院的患者的社会人口学、临床和超声心动图(Echo)特征。这是迄今为止尼日利亚最大的心衰患者队列之一。方法:横断面设计。社会人口学、临床和回声数据来自尼日利亚中北部伊洛林大学教学医院455名AHF患者。结果:患者的平均年龄为58.9±15.7岁(男性年龄大于女性,P=0.006)。265名(58.2%)为男性,大多数患者年龄>60岁,4.8%的患者患有2型糖尿病。53.2%的患者出现在纽约心脏协会III期和IV期。中位住院时间为11天(IQR,6-17),院内死亡率为11.6%。高血压是最常见的病因因素(62.4%),其次是扩张型心肌病17.6%、风湿性心脏病6.6%、围产期心肌病5.3%等。结论:我们研究中的AHF患者比尼日利亚和撒哈拉以南非洲先前研究中的患者年龄更大。高血压是AHF的主要驱动因素,患者大多患有临床晚期疾病,因此需要加强有关风险因素和早期表现的公共卫生教育。
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引用次数: 0
The prevalence of anxiety symptoms and associated factors among Nigerians newly posted for National Youth Service Corps programme in North-Western Nigeria 尼日利亚西北部新加入国家青年服务团项目的尼日利亚人焦虑症状和相关因素的患病率
Pub Date : 2021-07-07 DOI: 10.4314/REJHS.V9I3.4
A. Amoko, A. Ayodapo, T. O. Dele, H. Abitare
Objectives: This study was done to determine the prevalence of anxiety symptoms and assess the associated factors among new  members of national youth service corps (NYSC) programme in North-Western Nigeria.Method: A clinic-based descriptive cross-sectional study with convenient sampling method using selfadministered questionnaires was done among 157, 2018 Batch-C, corps members at Dakingari orientation camp in Kebbi State, over a period of three weeks. The prevalence of anxiety symptoms was determined using anxiety subset of Hospital Anxiety and Depression scale. Data were analyzed with SPSS-16 andChi-square was used to assess the degree of association between anxiety symptoms and certain factors. Pvalue of less than 0.05 was considered statistically significant.Results: The prevalence of anxiety symptoms was 50.0% among the respondents. There was a significant association between the presence of anxiety symptoms and age of the respondents (P-value= 0.006).Conclusion: The high prevalence of anxiety symptoms among the new NYSC members suggests the need to take preventive measures such as incorporation of subjects on what should be expected during service year into the undergraduate learning curriculum. Doctors attending to youth corps members, especially when on camp, should routinely screen them for anxiety symptoms. 
目的:本研究旨在确定尼日利亚西北部国家青年服务团(NYSC)项目新成员中焦虑症状的患病率,并评估相关因素。方法:在为期三周的时间里,采用基于临床的描述性横断面研究,采用自填问卷的抽样方法,对凯比州Dakingari迎新营的157名2018年c批部队成员进行了调查。使用医院焦虑抑郁量表的焦虑子集来确定焦虑症状的患病率。采用SPSS-16对数据进行分析,并采用卡方法评估焦虑症状与某些因素之间的关联程度。p值小于0.05认为有统计学意义。结果:被调查者中焦虑症状的患病率为50.0%。焦虑症状的出现与被调查者的年龄有显著的相关性(p值= 0.006)。结论:NYSC新成员中焦虑症状的高发提示有必要采取预防措施,如在本科学习课程中加入服务期间应该期待的科目。为青年军团成员看病的医生,尤其是在营地时,应该例行检查他们的焦虑症状。
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引用次数: 0
in vivo antibacterial and therapeutic properties of P. ostreatus against Staphylococcus aureus 平菇对金黄色葡萄球菌的体内抗菌和治疗作用
Pub Date : 2021-07-07 DOI: 10.4314/REJHS.V9I3.8
B. A. Oyekanmi, A. Onifade, I. Osho, O. Ajayi
Objectives: The use of natural products is embraced by a larger percentage of the world population. Most species of fungi including mushrooms produce useful secondary metabolites that stimulate the immune system against infection and diseases. Investigations were conducted to assay the therapeutic potentials of P. ostreatus against pathogenic staph infection.Methods: The methanol extract of P. ostreatus was prepared using the cold extraction method. Thirty Wistar albino rats weighing 82.0 g to 99.2 g were distributed into 6 groups of 5 and inoculated orally with actively growing Staphylococcus aureus suspension. P. ostreatus methanol extract LD > 5000 mg/kg 50 was used to determine the graded doses for the study. Graded doses of the extract 625 mg, 1250 mg, and 2500 mg were administered orally to the experimental animals for seven days.Results: The negative control and 625 mg had skin ulceration while 1250 mg to 2500 mg produced apparently healthy skin. Bacterial count after 7 days post-treatment was significantly high in the negative control and 625 mg dose (32.00 x 104 ± 6.10b; 43.40 x 104 ± 6.20b Cfu/ml) P< 0.05. Haematological and serum biochemical values were not significantly P < 0.05 affected. Pleurotus ostreatus administration at 1250 to 2500 mg produced a statistically low colony count that was comparable with 13.33 mg Ciprofloxacin and placebo.Conclusion: Pleurotus ostreatus at 1250 to 2500 mg was able to produce clinical recovery from S. aureus infection while 625 mg could not. The extract had no deleterious effect on the blood parameters, liver enzymes, and kidney biomarkers.  
目标:使用天然产品的人口占世界人口的比例更大。包括蘑菇在内的大多数真菌都会产生有用的次级代谢产物,刺激免疫系统抵抗感染和疾病。研究了平菇对葡萄球菌致病性感染的治疗潜力。方法:采用冷提取法制备平菇甲醇提取物。将30只体重82.0g至99.2g的Wistar白化大鼠分为6组,每组5只,并口服生长活跃的金黄色葡萄球菌悬浮液。平菇甲醇提取物LD>5000mg/kg 50用于确定研究的分级剂量。对实验动物口服625mg、1250mg和2500mg的分级剂量的提取物,持续7天。结果:阴性对照组和625 mg有皮肤溃疡,1250 mg至2500 mg有明显的健康皮肤。治疗后7天,阴性对照组的细菌计数显著较高,625 mg剂量(32.00 x 104±6.10b;43.40 x 104±6.20b Cfu/ml)P<0.05。血液学和血清生化值无显著性差异(P<0.05)。平菇1250至2500 mg给药产生的菌落计数在统计学上较低,与13.33 mg环丙沙星和安慰剂相当。结论:1250~2500mg的平菇对金黄色葡萄球菌感染有一定的临床恢复作用,625mg则不能。提取物对血液参数、肝脏酶和肾脏生物标志物没有有害影响。
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引用次数: 0
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