Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9384902
Zain Haider, Y. Drean, R. Sauleau, M. Zhadobov
A microdosimetric study is performed on a canonical biological cell model in the 60-GHz band. Complex permittivity data of dielectric models of the membrane, cytoplasm, and extracellular medium at microwaves has been extrapolated to millimeter-wave (mmWave) frequencies. A quasi-static electromagnetic (EM) analysis is employed to solve the Laplace equation numerically. The results demonstrate that cellular and sub-cellular membranes are no longer able to shield the intracellular organelles at mmWave frequencies, as it is the case at lower frequencies, and almost 100% of the electric field penetrates inside the cell, reaching intracellular organelles.
{"title":"Computational microdosimetry at cellular level at millimeter wave frequencies","authors":"Zain Haider, Y. Drean, R. Sauleau, M. Zhadobov","doi":"10.1109/IMBIoC47321.2020.9384902","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9384902","url":null,"abstract":"A microdosimetric study is performed on a canonical biological cell model in the 60-GHz band. Complex permittivity data of dielectric models of the membrane, cytoplasm, and extracellular medium at microwaves has been extrapolated to millimeter-wave (mmWave) frequencies. A quasi-static electromagnetic (EM) analysis is employed to solve the Laplace equation numerically. The results demonstrate that cellular and sub-cellular membranes are no longer able to shield the intracellular organelles at mmWave frequencies, as it is the case at lower frequencies, and almost 100% of the electric field penetrates inside the cell, reaching intracellular organelles.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122078779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385038
Andrea Tiloca, G. Pagana, D. Demarchi
Machine learning algorithms shown great potential in medical applications. This paper shows the use of it for noninvasive estimation of blood pressure through systems based on the unsupervised collection of signals. Our work is based on the study of morphology and timing characteristics of ECG and PPG signals like Pulse Transit Time, Heart Rate and others showed in this paper. We implement Random Forest regression algorithm to reach the final result of cuff-less Blood Pressure (BP) estimation with RMS error of 13 mmHg for SBP and 12.89 mmHg for DBP.
{"title":"A Random Tree Based Algorithm for Blood Pressure Estimation","authors":"Andrea Tiloca, G. Pagana, D. Demarchi","doi":"10.1109/IMBIoC47321.2020.9385038","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385038","url":null,"abstract":"Machine learning algorithms shown great potential in medical applications. This paper shows the use of it for noninvasive estimation of blood pressure through systems based on the unsupervised collection of signals. Our work is based on the study of morphology and timing characteristics of ECG and PPG signals like Pulse Transit Time, Heart Rate and others showed in this paper. We implement Random Forest regression algorithm to reach the final result of cuff-less Blood Pressure (BP) estimation with RMS error of 13 mmHg for SBP and 12.89 mmHg for DBP.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124184067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385039
Divya Baskaran, K. Arunachalam
The performance of the genetic algorithm (GA) and particle swarm optimization (PSO) was compared to identify the best-suited algorithm for hyperthermia treatment planning (HTP) of breast cancer. Both algorithms were tested on four heterogeneous patient breast models derived from magnetic resonance (MR) images. Electromagnetic (EM) simulations indicate that PSO induces 5.7% less hotspot to target quotient (HTQ) compared to GA. However, coupled EM and thermal simulations of four patient models indicate that GA based HTP induces $boldsymbol{1.25}^{circ} mathbf{C}-boldsymbol{3.87}^{circ}mathbf{C}$ higher average temperature in cancer tissue with limited thermal hotspots in healthy tissue when compared to PSO algorithm. This was observed to be due to the low power level assigned to each channel by PSO compared to GA. Coupled simulations of heterogeneous patient models indicate GA is a better global optimization algorithm for HTP of breast cancer.
{"title":"Comparison of two global optimization techniques for hyperthermia treatment planning of breast cancer: Coupled electromagnetic and thermal simulation study","authors":"Divya Baskaran, K. Arunachalam","doi":"10.1109/IMBIoC47321.2020.9385039","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385039","url":null,"abstract":"The performance of the genetic algorithm (GA) and particle swarm optimization (PSO) was compared to identify the best-suited algorithm for hyperthermia treatment planning (HTP) of breast cancer. Both algorithms were tested on four heterogeneous patient breast models derived from magnetic resonance (MR) images. Electromagnetic (EM) simulations indicate that PSO induces 5.7% less hotspot to target quotient (HTQ) compared to GA. However, coupled EM and thermal simulations of four patient models indicate that GA based HTP induces $boldsymbol{1.25}^{circ} mathbf{C}-boldsymbol{3.87}^{circ}mathbf{C}$ higher average temperature in cancer tissue with limited thermal hotspots in healthy tissue when compared to PSO algorithm. This was observed to be due to the low power level assigned to each channel by PSO compared to GA. Coupled simulations of heterogeneous patient models indicate GA is a better global optimization algorithm for HTP of breast cancer.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115857653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385009
S. Costanzo, G. Lopez
A phaseless imaging approach, based on the postprocessing of amplitude-only data, is described in the present work. A Contrast Source inversion procedure is adopted, but not requiring a preliminary phase retrieval stage. The reconstruction capabilities of the proposed approach are tested on a numerical breast model, by assuming different coupling mediums.
{"title":"Phaseless Microwave Breast Imaging: Preliminary Study and Coupling Medium Effects","authors":"S. Costanzo, G. Lopez","doi":"10.1109/IMBIoC47321.2020.9385009","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385009","url":null,"abstract":"A phaseless imaging approach, based on the postprocessing of amplitude-only data, is described in the present work. A Contrast Source inversion procedure is adopted, but not requiring a preliminary phase retrieval stage. The reconstruction capabilities of the proposed approach are tested on a numerical breast model, by assuming different coupling mediums.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115943704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385034
Mahdi Srour, B. Potelon, C. Quendo, C. Person, J. Carré
This paper presents a biosensor based on a resonant technique that quantifies the glucose concentration of a water/glucose mixture inserted into a standard medical test tube, which is located in the middle of a waveguide. The biosensor provides real-time data about the concentration of the solution under test by means of microwave non-invasive measurements. Interaction between electromagnetic fields and the dielectric solution to be measured (water/glucose mixture) results in a change of the S-parameters, which are observed in the 2.6 to 3.95 GHz range. The technique presented here could be further used for the monitoring of other liquids or aqueous solutions.
{"title":"Biosensor Based on a Resonant Technique for Aqueous Glucose Monitoring Using Standardized Medical Test Tubes","authors":"Mahdi Srour, B. Potelon, C. Quendo, C. Person, J. Carré","doi":"10.1109/IMBIoC47321.2020.9385034","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385034","url":null,"abstract":"This paper presents a biosensor based on a resonant technique that quantifies the glucose concentration of a water/glucose mixture inserted into a standard medical test tube, which is located in the middle of a waveguide. The biosensor provides real-time data about the concentration of the solution under test by means of microwave non-invasive measurements. Interaction between electromagnetic fields and the dielectric solution to be measured (water/glucose mixture) results in a change of the S-parameters, which are observed in the 2.6 to 3.95 GHz range. The technique presented here could be further used for the monitoring of other liquids or aqueous solutions.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115500480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385016
R. Bharadwaj, S. Koul
This paper presents daily activity recognition using wearable ultra-wideband technology. Channel parameters are analyzed for various postures occurring during the daily activity which act as key features to estimate the activity trend. Compact wearable antennas are placed on suitable locations on the human subject for each activity (walking, standing and sitting) studied in order to have maximum direct path propagation between the two wearable on-body nodes. It is observed that the three activities analyzed show distinct variation in the channel features making it possible to classify the activities through statistical analysis and inter-distance measurements between the wearable nodes. Low correlation is observed between the activity patterns with 0.01-0.3 correlation coefficient values. This indicates that the activities can be easily distinguished from each other using channel information. The work will be suitable for tracking, rehabilitation and activity monitoring applications in the healthcare domain.
{"title":"Wearable Ultra Wideband Technology for Daily Activity Recognition","authors":"R. Bharadwaj, S. Koul","doi":"10.1109/IMBIoC47321.2020.9385016","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385016","url":null,"abstract":"This paper presents daily activity recognition using wearable ultra-wideband technology. Channel parameters are analyzed for various postures occurring during the daily activity which act as key features to estimate the activity trend. Compact wearable antennas are placed on suitable locations on the human subject for each activity (walking, standing and sitting) studied in order to have maximum direct path propagation between the two wearable on-body nodes. It is observed that the three activities analyzed show distinct variation in the channel features making it possible to classify the activities through statistical analysis and inter-distance measurements between the wearable nodes. Low correlation is observed between the activity patterns with 0.01-0.3 correlation coefficient values. This indicates that the activities can be easily distinguished from each other using channel information. The work will be suitable for tracking, rehabilitation and activity monitoring applications in the healthcare domain.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126209404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9384903
M. Gil, P. Vélez, F. Aznar-Ballesta, A. Mesegar-Ruiz, Jonatan Muñoz-Enano, Marcos Duque, F. Martín
We propose the use of electro-inductive wave (EIW) transmission lines based on complementary split-ring resonators (CSRR) to implement a differential-mode microwave sensor for biological fluid sensing purposes. Differential-mode operation is achieved by comparing the response of the device loaded with a reference (REF) sample to the one of the sensor loaded with a sample under test (SUT). By this means, any alteration or difference in the SUT as compared to the REF sample (seen as an asymmetry) can be detected. The designed and fabricated device has been validated by considering ethanol and glucose solutions in pure deionized (DI) water. The main relevant aspect of the proposed sensor is the high sensitivity and resolution. Thus, this device is especially useful for the characterization of solute content in very diluted solutions.
{"title":"Electro-inductive Wave Transmission Line based Microfluidic Microwave Sensor","authors":"M. Gil, P. Vélez, F. Aznar-Ballesta, A. Mesegar-Ruiz, Jonatan Muñoz-Enano, Marcos Duque, F. Martín","doi":"10.1109/IMBIoC47321.2020.9384903","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9384903","url":null,"abstract":"We propose the use of electro-inductive wave (EIW) transmission lines based on complementary split-ring resonators (CSRR) to implement a differential-mode microwave sensor for biological fluid sensing purposes. Differential-mode operation is achieved by comparing the response of the device loaded with a reference (REF) sample to the one of the sensor loaded with a sample under test (SUT). By this means, any alteration or difference in the SUT as compared to the REF sample (seen as an asymmetry) can be detected. The designed and fabricated device has been validated by considering ethanol and glucose solutions in pure deionized (DI) water. The main relevant aspect of the proposed sensor is the high sensitivity and resolution. Thus, this device is especially useful for the characterization of solute content in very diluted solutions.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"303 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123126392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385011
Jelena Kolosnjaj-Tabi, Géraldine Albérola, S. Augé, A. Tamra, D. Dubuc, K. Grenier, M. Rols
Herein we present the assessment of RF-induced cell membrane effects assessment in multicellular spheroids, which are three-dimensional tissue models resembling small avascular tumors. The RF exposure was performed in a dedicated RF applicator, which allowed a precise RF metrology as well as calibrated and systematized conditions of application of electromagnetic fields to multiple 3D multicellular spheroids. The used RF micro-device allowed us varying different RF parameters (such as frequency, power, or modulation) in order to evaluate RF-related biological effects on the membranes of cells constituting the multicellular spheroids. The effects of electromagnetic signals were assessed on cancer cells spheroids made with HCT-116 cells. Appraised parameters included the evaluation of cell membrane integrity, and the assessment of spheroids global structure after illumination. After RF exposure at SAR values ranging from 0.4 to 7.5 kW/kg, we did not observe any detrimental effects on the cell membrane level. Moreover, the spheroids exhibited an unmodified architecture.
{"title":"Evaluation of Cell Membrane Effects After 3D Multicellular Spheroids RF Exposure","authors":"Jelena Kolosnjaj-Tabi, Géraldine Albérola, S. Augé, A. Tamra, D. Dubuc, K. Grenier, M. Rols","doi":"10.1109/IMBIoC47321.2020.9385011","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385011","url":null,"abstract":"Herein we present the assessment of RF-induced cell membrane effects assessment in multicellular spheroids, which are three-dimensional tissue models resembling small avascular tumors. The RF exposure was performed in a dedicated RF applicator, which allowed a precise RF metrology as well as calibrated and systematized conditions of application of electromagnetic fields to multiple 3D multicellular spheroids. The used RF micro-device allowed us varying different RF parameters (such as frequency, power, or modulation) in order to evaluate RF-related biological effects on the membranes of cells constituting the multicellular spheroids. The effects of electromagnetic signals were assessed on cancer cells spheroids made with HCT-116 cells. Appraised parameters included the evaluation of cell membrane integrity, and the assessment of spheroids global structure after illumination. After RF exposure at SAR values ranging from 0.4 to 7.5 kW/kg, we did not observe any detrimental effects on the cell membrane level. Moreover, the spheroids exhibited an unmodified architecture.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128372999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385027
G. Paolini, Michael Feliciani, D. Masotti, A. Costanzo
This work presents a research about a 5.8 GHz system for vital signals monitoring, specifically human breath. The system consists of two main components: a Self-Injection Locked Oscillator (SILO), whose input and output ports are aperture-coupled to a dual-polarized patch antenna, and a passive receiver, coupled to the SILO output port, consisting of the cascade connection of a peak detector and a full–wave RF–to–DC rectifier. The SILO generates the carrier, that is frequency-modulated by chest displacements and backscattered to the SILO itself. The latter is loosely coupled to the passive receiving sub-system. In this way, the SILO output signal is simultaneously demodulated by the detector, and DC-converted to provide energy for the wireless communication of the received vital signals, e.g. by means of an IoT (Internet of Things) low-power node. The system is designed for being fully wearable; it can be mounted inside a plastic case and worn by the user under test at chest–level position. Critical breath rates can be detected and sent to a caregiver, thus enabling monitoring of chronic diseases, such as bradypnea or tachypnea, while performing a normal life.
{"title":"Toward an Energy-Autonomous Wearable System for Human Breath Detection","authors":"G. Paolini, Michael Feliciani, D. Masotti, A. Costanzo","doi":"10.1109/IMBIoC47321.2020.9385027","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385027","url":null,"abstract":"This work presents a research about a 5.8 GHz system for vital signals monitoring, specifically human breath. The system consists of two main components: a Self-Injection Locked Oscillator (SILO), whose input and output ports are aperture-coupled to a dual-polarized patch antenna, and a passive receiver, coupled to the SILO output port, consisting of the cascade connection of a peak detector and a full–wave RF–to–DC rectifier. The SILO generates the carrier, that is frequency-modulated by chest displacements and backscattered to the SILO itself. The latter is loosely coupled to the passive receiving sub-system. In this way, the SILO output signal is simultaneously demodulated by the detector, and DC-converted to provide energy for the wireless communication of the received vital signals, e.g. by means of an IoT (Internet of Things) low-power node. The system is designed for being fully wearable; it can be mounted inside a plastic case and worn by the user under test at chest–level position. Critical breath rates can be detected and sent to a caregiver, thus enabling monitoring of chronic diseases, such as bradypnea or tachypnea, while performing a normal life.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"276 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134212108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385053
R. Caverly
This paper presents the results of an investigation of PIN diode switching speed using a variety of PIN diode types that include high speed receive switching devices as well as high power transmitting PIN diodes. A short introduction on the PIN diode simulation model will be provided and then simulations of a common MRI transmit/receive switch will be used to compare the different device switching speeds. The results show that thick I-region diodes are shown to exhibit extremely low resistance values at high currents, providing low insertion loss at the high RF powers in transmitting, active detune and block switching applications as well as robust blocking/detuning functions, but at a slower switching rate compared with thinner devices.
{"title":"PIN Diode Switching Speed for MRI Applications","authors":"R. Caverly","doi":"10.1109/IMBIoC47321.2020.9385053","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385053","url":null,"abstract":"This paper presents the results of an investigation of PIN diode switching speed using a variety of PIN diode types that include high speed receive switching devices as well as high power transmitting PIN diodes. A short introduction on the PIN diode simulation model will be provided and then simulations of a common MRI transmit/receive switch will be used to compare the different device switching speeds. The results show that thick I-region diodes are shown to exhibit extremely low resistance values at high currents, providing low insertion loss at the high RF powers in transmitting, active detune and block switching applications as well as robust blocking/detuning functions, but at a slower switching rate compared with thinner devices.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124799355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}