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Effect of Transcranial Direct Current Stimulation with Balance Training in a Middle-Aged Population: Randomized Double-Blind Sham-Controlled Trial. 经颅直流电刺激与平衡训练对中年人群的影响:随机双盲假对照试验》。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-01-18 DOI: 10.1089/jicm.2023.0034
Juho Jung, Jhosedyn Carolaym Salazar Fajardo, Seongkuk Kim, Byeongsu Kim, Sejun Oh, BumChul Yoon

Introduction: The first signs of deteriorated balance impairment begin during middle age. Early intervention could delay the fall risk in older populations; hence, addressing balance deficits during this age is crucial. The authors aimed to determine the effects of transcranial direct current stimulation (tDCS) combined with balance training (BT) on the improvement of static and dynamic balance in a middle-aged population, along with the participants' safety and satisfaction. Methods: Participants (n = 28) were randomized into two groups: active tDCS (active tDCS + BT) and sham tDCS (sham tDCS + BT). Both groups received the intervention thrice a week for 6 weeks. Dynamic and static balance were assessed by sway rate changes with eyes open and closed, and the functional reach test and a postintervention survey were conducted to assess participants' safety and satisfaction. Results: The active tDCS group showed significantly greater static and dynamic balance improvements in sway scores. The surveys demonstrated the safety of the program and satisfaction of 80% of the participants with the combined intervention. Conclusion: tDCS could be used in a middle-aged population as part of regular BT to improve balance and minimize the risk of balance deficits in older populations while ensuring patient safety and satisfaction. This study is a subanalysis of a larger clinical trial that included young adults as well (Clinical trial number: KCT0007414).

导言平衡障碍恶化的最初迹象始于中年。早期干预可以延缓老年人跌倒的风险;因此,在这个年龄段解决平衡障碍问题至关重要。作者旨在确定经颅直流电刺激(tDCS)结合平衡训练(BT)对改善中年人群静态和动态平衡的效果,以及参与者的安全性和满意度。研究方法将参与者(n = 28)随机分为两组:主动 tDCS 组(主动 tDCS + BT)和假 tDCS 组(假 tDCS + BT)。两组均每周接受三次干预,为期 6 周。通过睁眼和闭眼时的摇摆率变化评估动态和静态平衡,并进行功能性触地测试和干预后调查,以评估参与者的安全性和满意度。结果积极的 tDCS 组在摇摆评分的静态和动态平衡方面有明显改善。调查显示,该项目安全可靠,80% 的参与者对综合干预表示满意。结论:作为常规 BT 的一部分,tDCS 可用于中年人群,以改善老年人群的平衡能力并将平衡障碍的风险降至最低,同时确保患者的安全性和满意度。本研究是一项大型临床试验的子分析,该试验也包括年轻人(临床试验编号:KCT0007414)。
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引用次数: 0
The Association Between Well-Being and Empathy in Medical Residents: A Cross-Sectional Survey. 医学住院医生的幸福感与同情心之间的关系:一项横断面调查
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-27 DOI: 10.1089/jicm.2023.0116
Theodora L Swenson, Reza Ehsanian, Richard T Tran, Timothy R Petersen, David J Kennedy, Megan Roche, Marily Oppezzo, Douglas L Noordsy, Michael Fredericson

Objective: To evaluate the extent to which personal well-being may be associated with empathy, while controlling for potential confounders. Settings/Location: Residency programs throughout the United States. Subjects: A total of 407 medical residents from residencies including general medicine, surgery, specialized and diagnostic medicine participated in this study. Outcome Measures: Well-being was measured using the modified existential well-being subscale of the spiritual well-being scale. Empathy was measured using the Jefferson Scale of Empathy. Results: Well-being was found to be positively correlated with empathy when adjusted for possible confounders (p < 0.001). In addition to well-being, other factors noted to be statistically significant contributors to higher empathy scores while controlling for the others included age, gender, year in residency, specialty, and work-hours (p < 0.05 for each). After controlling for these factors, a resident's year in residency was not found to be a statistically significant contributor to empathy score. Conclusions: In this study, well-being was associated with empathy in medical and surgical residents. Empathy is a fundamental component of physician competency, and its development is an essential aspect of medical training. These findings suggest that efforts to increase well-being may promote empathy among medical residents.

目的在控制潜在混杂因素的情况下,评估个人幸福感与移情的关联程度。环境/地点:美国各地的住院医师培训项目。研究对象共有 407 名来自普通内科、外科、专科和诊断内科的住院医师参与了本研究。结果测量:幸福感采用精神幸福感量表的改良存在幸福感分量表进行测量。移情采用杰斐逊移情量表进行测量。结果在对可能的混杂因素进行调整后,发现幸福感与移情呈正相关(P P 结论):在这项研究中,内科和外科住院医师的幸福感与移情相关。同理心是医生能力的一个基本组成部分,培养同理心是医学培训的一个重要方面。这些研究结果表明,努力提高幸福感可促进内科住院医师的移情能力。
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引用次数: 0
Mapping Evidence-Based Non-Opioid and Non-Pharmacological Pain Management Modalities Across Minnesota: The Non-Opioid Pain Alleviation Information Network Project. 绘制明尼苏达州循证非阿片类药物和非药物疼痛管理模式图:非阿片类药物缓解疼痛信息网络项目。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2023-12-18 DOI: 10.1089/jicm.2023.0031
Arti Prasad, Richard Printon, Miamoua Vang, Sophie Kurschner, Jeffery A Dusek

Objective: The Non-Opioid Pain Alleviation Information Network (NOPAINMN) project was designed to identify, consolidate, and map evidence-based non-opioid and non-pharmacological pain management complementary and integrative health (CIH) modalities for chronic pain management across Minnesota into a searchable and informational website (www.nopainmn.org ). Methods: The Academic Consortium for Integrative Medicine & Health's Pain Task Force White Paper identifying evidence-based research of non-pharmacological pain practice (NPPC) was reviewed and referenced. National and state certifying boards and accrediting organizations for NPPC modalities were accessed to identify Minnesota-based NPPC providers' name, business/health-system affiliation, address, contact information, and credentials. The NOPAINMN website displays these data in a consumer-facing website with searchable fields such as NPPC modality type, and location with varying distances. The website was β-tested by practitioners and stakeholders for optimization. Eight main NPPC modalities and their respective subcategories were identified and mapped: Acupuncture; Integrative Medical Care (Functional medicine consultation and Integrative medicine consultation); Massage Therapy; Mind-Body Therapies (Biofeedback, Clinical Hypnosis, Mindfulness-Based Stress Reduction, and Music Therapy); Movement Therapies (Tai Chi, qigong, and Yoga Therapy); Psychology (Cognitive Behavioral Therapy); Rehabilitative Therapies (Physical and Occupational Therapy); and Spinal Manipulation. Results: All information compiled resulted in 17,155 providers/practitioners. Physical Therapy had the greatest number of reported providers (n = 5224), followed by Occupational Therapy (n = 3792), Psychology (n = 3324), Chiropractic (n = 3033), Acupuncture (n = 591), and Massage Therapy (n = 544). The Resource Map included 56 major health systems, 686 facilities, 2651 solo or private group practices, and 14 academic training schools. With web-based cross-referencing, providers and facilities were affiliated and linked with health systems to produce an interconnected mapping system. β-Testing with patients found that the website was reported as relatively easy to use and informative. Conclusion: The website was created to assist individuals, health care providers, insurance carriers, and health care facilities in finding evidence-based information and resources on NPPC to guide, support, and proactively manage and engage chronic pain patients across Minnesota.

目标:非阿片类药物疼痛缓解信息网络(NOPAINMN)项目旨在识别、整合明尼苏达州的非阿片类药物和非药物疼痛管理补充和综合健康(CIH)模式,并将其绘制成一个可搜索的信息网站 (www.nopainmn.org)。方法:审查并参考了 "综合医学与健康学术联盟疼痛特别工作组白皮书",该白皮书确定了非药物止痛实践(NPPC)的循证研究。访问了国家和州 NPPC 模式认证委员会和认证组织,以确定明尼苏达州 NPPC 提供者的姓名、企业/医疗系统隶属关系、地址、联系信息和证书。NOPAINMN 网站在一个面向消费者的网站上显示这些数据,并提供可搜索字段,如 NPPC 方式类型和不同距离的地点。从业人员和利益相关者对网站进行了β测试,以优化网站。确定并绘制了八种主要的 NPPC 模式及其各自的子类别:针灸;中西医结合医疗(功能医学咨询和中西医结合医学咨询);按摩疗法;身心疗法(生物反馈、临床催眠、正念减压和音乐疗法);运动疗法(太极、气功和瑜伽疗法);心理学(认知行为疗法);康复疗法(物理疗法和职业疗法);以及脊柱手法治疗。结果:汇总所有信息后,共有 17,155 名提供者/从业者。理疗科报告的提供者人数最多(n = 5224),其次是职业疗法(n = 3792)、心理学(n = 3324)、整脊(n = 3033)、针灸(n = 591)和按摩疗法(n = 544)。资源地图包括 56 个主要医疗系统、686 家医疗机构、2651 个个人或私人团体诊所以及 14 所学术培训学校。通过网络交叉引用,医疗机构和设施与医疗系统建立了关联和联系,形成了一个相互连接的地图系统。β 对患者进行测试后发现,该网站使用起来相对简单,信息量也比较大。结论:创建该网站的目的是帮助个人、医疗服务提供者、保险公司和医疗机构查找有关 NPPC 的循证信息和资源,以指导、支持和主动管理明尼苏达州的慢性疼痛患者并使其参与其中。
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引用次数: 0
Embracing Open Science: Paving the Way for Transparent, Collaborative, and Inclusive Research in Traditional, Complementary, and Integrative Medicine. 拥抱开放科学:为传统医学、补充医学和中西医结合领域的透明、协作和包容性研究铺平道路》(Paving the Way for Transparent, Collaborative, Inclusive Research in Traditional, Complementary, and Integrative Medicine)。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-06-20 DOI: 10.1089/jicm.2024.0346
Jeremy Y Ng, Holger Cramer
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引用次数: 0
A Cross-Sectional Investigation of Trait Mindfulness, Concussion Symptom Severity, and Quality of Life in Adults with Persisting Symptoms Postconcussion. 对脑震荡后症状持续存在的成年人的正念特质、脑震荡症状严重程度和生活质量的横断面调查。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-04-02 DOI: 10.1089/jicm.2023.0516
Molly Cairncross, Andrée-Anne Ledoux, Jonathan Greenberg, Noah D Silverberg

Individual differences in mindfulness may impact quality of life after concussion. In a cross-sectional analysis, the moderating effect of mindfulness was tested on the association between symptom severity and quality of life in adults with persisting postconcussion symptoms (N = 85). Mindfulness and symptom severity were independently associated with quality of life; however, mindfulness did not moderate this association. "Nonreactivity" was independently associated with quality of life; however, it was not a significant moderator. Taking a nonreactive stance, or allowing experiences to come and go without effort to change them, may be relevant to quality-of-life outcomes after concussion.

正念的个体差异可能会影响脑震荡后的生活质量。在一项横断面分析中,我们测试了正念对脑震荡后症状持续存在的成年人(人数=85)的症状严重程度与生活质量之间关系的调节作用。正念和症状严重程度与生活质量独立相关;但是,正念并不能调节这种关联。"不反应 "与生活质量有独立的关联;但它并不是一个重要的调节因素。在脑震荡后,采取不反应的姿态,或允许经历来来去去,而不去努力改变它们,可能与生活质量的结果有关。
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引用次数: 0
The Society for Integrative Oncology-American Society of Clinical Oncology Joint Guidelines on Integrative Therapies for Symptom Management-Overview and Key Recommendations. 美国中西医结合肿瘤学会--美国临床肿瘤学会症状管理中西医结合疗法联合指南--概述和主要建议》(The Society for Integrative Oncology-American Society of Clinical Oncology Joint Guidelines on Integrative Therapies for Symptom Management-Overview and Key Recommendations)。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 DOI: 10.1089/jicm.2024.0452
Linda E Carlson, Debu Tripathy, Suzanna M Zick, Lynda G Balneaves, Richard T Lee, Heather Greenlee
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引用次数: 0
Implementation and Evaluation of a National Well-Being Curriculum for KL2 Scholars. 针对 KL2 学者的国家幸福课程的实施与评估。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-18 DOI: 10.1089/jicm.2023.0701
Gretchen Roman, Lunthita M Duthely, Jacqueline Attia, Abby E Spike, Scott McIntosh, Susan N Pusek, Darshan H Mehta, Miriam A Bredella

Introduction: The study aimed to pilot test a well-being curriculum for KL2 scholars to be used across the Clinical and Translational Science Award consortium. Methods: Between November 2022, and May 2023, 36 KL2 scholars from 25 hubs participated in the program. The General Well-Being Index for U.S. Workers and the Patient Reported Outcomes Measurement Information System (PROMIS-29) were completed by scholars before and after the program. Results: Postparticipation, there was a trend of improvement in the domains of well-being, sleep, anxiety, and fatigue. Conclusion: Implementing a virtual synchronous well-being curriculum allowed the scholars to connect across the consortium and improve their well-being.

简介本研究旨在对 KL2 学者的幸福课程进行试点测试,以便在整个临床与转化科学奖联盟中使用。研究方法2022年11月至2023年5月期间,来自25个中心的36名KL2学者参加了该项目。学者们在项目前后分别完成了美国工人总体幸福指数(General Well-Being Index for U.S. Workers)和患者报告结果测量信息系统(PROMIS-29)。结果显示参加计划后,在幸福感、睡眠、焦虑和疲劳等方面均有改善趋势。结论通过实施虚拟同步幸福感课程,学者们能够在整个联盟中建立联系,并改善他们的幸福感。
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引用次数: 0
Mind-Body Interventions for Youth with Chronic Medical Conditions: A Scoping Review of the Literature. 对患有慢性疾病的青少年进行身心干预:文献综述。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-18 DOI: 10.1089/jicm.2023.0427
Roshini Srinivasan, Molly McVoy, Mandy Neudecker, Mina Kumari Divan, Amy Wu, Michelle E Cascio, Jeffery A Dusek, David W Miller

Background and purpose: Little is known about the applicability, utilization, and effectiveness of mind-body interventions (MBIs) for conditions that are not predominantly pain, neoplastic, or psychiatric, particularly in pediatric patients. This scoping review describes research pertaining to such interventions in youth with nonpain, noncancer, and nonpsychiatric predominant chronic medical conditions. Methods: Searches of EBSCO CINAHL, Elsevier Scopus, Ovid for MEDLINE, and Ovid PsycInfo were conducted to investigate MBIs in youth under 18 years of age with nonpain, noncancer, and nonpsychiatric predominant chronic medical conditions. Articles published between 2010 and 2020 were included. Abstracts were screened by three authors for inclusion, and disagreements were resolved by a designated author. Selected full-text articles were divided among all authors for review of study quality, intervention feasibility and acceptability, and effectiveness. Results: The search yielded 1010 titles with 15 meeting the final inclusion criteria, studying a total of 641 youth. Participants ranged in age from 6 to 19 years (included studies had data on participants <18 years reported separately); 61.5% were female (n = 394) and 38.5% were male (n = 247). The two most common conditions studied were asthma and irritable bowel syndrome, with yoga being the most popular intervention. Overall, MBIs showed promising preliminary evidence for improving symptoms and quality of life in youth with chronic medical conditions. Conclusion: MBIs have been successfully delivered and show promise in symptom palliation and quality of life improvement for youth with a variety of chronic medical conditions. More data from high-quality randomized controlled trials are needed to further characterize the effectiveness of specific modalities for specific conditions.

背景和目的:人们对身心干预(MBI)在非疼痛、肿瘤或精神疾病方面的适用性、利用率和有效性知之甚少,尤其是在儿科患者中。本范围综述介绍了针对非疼痛、非癌症和非精神疾病为主的慢性病青少年的此类干预措施的相关研究。研究方法对 EBSCO CINAHL、Elsevier Scopus、Ovid for MEDLINE 和 Ovid PsycInfo 进行了检索,以研究针对 18 岁以下患有非疼痛、非癌症和非精神疾病的青少年的 MBI。研究纳入了 2010 年至 2020 年间发表的文章。摘要由三位作者进行筛选,有异议的由指定作者解决。选取的文章全文由所有作者共同审查研究质量、干预措施的可行性和可接受性以及有效性。结果:搜索结果显示,共有 1010 篇文章符合最终纳入标准,其中 15 篇研究了 641 名青少年。参与者的年龄从 6 岁到 19 岁不等(纳入研究的参与者数据 n = 394),38.5% 为男性(n = 247)。研究中最常见的两种疾病是哮喘和肠易激综合征,瑜伽是最受欢迎的干预措施。总体而言,MBIs 在改善患有慢性疾病的青少年的症状和生活质量方面显示出良好的初步效果。结论:MBIs已成功应用于多种慢性病患者,在缓解症状和提高生活质量方面显示出良好的前景。我们需要更多来自高质量随机对照试验的数据,以进一步确定特定模式对特定病症的有效性。
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引用次数: 0
Australian National Complementary Medicine Workforce Survey: A Profile of Practitioners and Their Practices. 澳大利亚全国补充医学从业人员调查:从业人员及其诊所概况。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2023-12-26 DOI: 10.1089/jicm.2023.0443
Sandra Grace, Kathryn Baltrotsky

Introduction: Recent years have seen rapid changes to traditional, complementary, and integrative medicine (TCIM) practices in Australia associated with increased interest in TCIM during the COVID-19 pandemic and reorganization of practice delivery methods. This study aimed to update the understanding of the current TCIM workforce in Australia. Methods: Representatives of six TCIM professional organizations developed a survey for e-mail distribution to members. The anonymous online Qualtrics survey was based on previous surveys to identify workforce trends over time. Survey data were analyzed descriptively using Qualtrics and STATA statistical software (version 16). Results: Responses were recorded from 1921 participants. Respondents were predominantly female (79.7%); 71.8% were aged over 45 years. Remedial massage therapists represented 32.1% and naturopaths represented 23.7% of respondents. Highest qualifications were diplomas (37.7%), bachelor's degrees (28.9%), and advanced diplomas (21.8%). Metropolitan locations accounted for 68.1% of practices. Solo private practice was the main practice setting (59.8%); 13.8% practiced in group private practice with TCIM practitioners; and 10.6% practiced with allied health practitioners. Approximately three quarters of respondents (73.9%) saw 0-5 new clients per week; 42.2% had 0-5 follow-up consultations per week. Collaboration rates with TCIM practitioners, other non-TCIM practitioners, and general medical practitioners (GPs) were 68.7%, 24.4%, and 9.2%, respectively. A total of 93% did not suspect an adverse event from their treatment in the past year. Businesses of 75.9% of respondents were reportedly affected by the pandemic. Discussion: Comparisons with previous surveys show ongoing predominance of female practitioners, an aging workforce, a high proportion of remedial massage and naturopathy practitioners, and an increasingly qualified TCIM workforce. There was little change in the very low number of adverse events suspected by practitioners, number of consultations per week, and low levels of income of most TCIM practitioners compared with the average income in Australia. Respondents collaborated at similar rates as in the past; however, more with TCIM practitioners than with GPs.

简介:近年来,澳大利亚的传统、补充和综合医学(TCIM)实践发生了快速变化,这与 COVID-19 大流行期间人们对 TCIM 的兴趣增加以及实践方法的重组有关。本研究旨在更新对澳大利亚当前传统医学和综合医学从业人员的了解。方法:六个 TCIM 专业组织的代表编制了一份调查问卷,通过电子邮件发送给成员。这项匿名在线 Qualtrics 调查以之前的调查为基础,旨在确定劳动力随时间变化的趋势。调查数据使用 Qualtrics 和 STATA 统计软件(第 16 版)进行描述性分析。结果共记录了 1921 名参与者的回答。受访者以女性为主(79.7%);71.8%的受访者年龄在 45 岁以上。补救按摩师占 32.1%,自然疗法师占 23.7%。最高学历为文凭(37.7%)、学士学位(28.9%)和高级文凭(21.8%)。在大都市执业的占 68.1%。个人私人诊所是主要的执业机构(59.8%);13.8%与TCIM执业医师一起在团体私人诊所执业;10.6%与专职医疗执业医师一起执业。约四分之三的受访者(73.9%)每周接诊 0-5 名新客户;42.2%每周复诊 0-5 次。与 TCIM 医生、其他非 TCIM 医生和全科医生(GP)的合作率分别为 68.7%、24.4% 和 9.2%。共有 93% 的人在过去一年中没有怀疑自己的治疗出现过不良反应。据报告,75.9%的受访者的生意受到了大流行病的影响。讨论情况:与之前的调查相比,女性从业人员占多数,从业人员老龄化,补救性按摩和自然疗法从业人员比例较高,TCIM从业人员的资质越来越高。与澳大利亚的平均收入水平相比,从业人员怀疑的不良事件数量、每周咨询次数以及大多数 TCIM 从业人员收入水平较低的情况几乎没有变化。受访者的合作率与过去相似,但与 TCIM 从业人员的合作多于与全科医生的合作。
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引用次数: 0
Efficacy of Individualized Homeopathic Medicines in the Treatment of Sciatica Pain: Double-Blind, Randomized, Placebo-Controlled Trial. 个性化顺势疗法药物治疗坐骨神经痛的疗效:双盲、随机、安慰剂对照试验。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-01 DOI: 10.1089/jicm.2023.0260
Siddharth Kumar Das, Trishita Basu, Saleema Naaz Tabassum, Ashish Sarkar, Shubhamoy Ghosh, Munmun Koley, Subhranil Saha, Arunava Nath, Srimanta Khamrui

Objectives: Sciatica is a debilitating condition that causes pain in its distribution or in the lumbosacral nerve root that is connected to it. Although there are claims that homeopathy can reduce sciatica pain, systematic scientific proof is currently lacking. The objective of the trial was to determine whether individualized homeopathic medicines (IHMs) were as effective as identical-looking placebos in treating sciatica pain. Design: This is a double-blind, randomized (1:1), two parallel arms, placebo-controlled trial. Setting: The study was conducted at Mahesh Bhattacharyya Homoeopathic Medical College and Hospital, Howrah, West Bengal, India. Subjects: Sixty participants with sciatica pain were included in this study. Interventions: Verum (n = 30; IHMs plus concomitant care) versus control (n = 30; placebos plus concomitant care). Outcome measures: Primary-Sciatica Bothersome Index (SBI) and Sciatica Frequency Index (SFI) scores and secondary-Roland Morris Pain and Disability Questionnaire (RMPDQ), Short Form McGill Pain Questionnaire (SF-MPQ), and Oswestry Low Back Pain Questionnaire (OLBPQ) scores: all of them were measured at baseline, and every month, up to 3 months. Results: Intention-to-treat sample (n = 60) was analyzed. Group differences were examined by two-way (split-half) repeated measure analysis of variance, primarily accounting for between groups and time interactions, and additionally, by unpaired t tests comparing the estimates obtained individually every month. The level of significance was set at p < 0.025 and <0.05 two tailed for the primary and secondary outcomes, respectively. Group differences could not achieve significance in SBI (p = 0.044), SFI (p = 0.080), and RMPDQ scores (p = 0.134), but were significant for SF-MPQ (p = 0.007) and OLBPQ (p = 0.036). Gnaphalium polycephalum (n = 6; 10%) was the most frequently prescribed medicine. No harm, serious adverse events, or intercurrent illnesses were recorded in either of the groups. Conclusions: The primary outcome failed to demonstrate evidently that homeopathy was effective beyond placebo, and the trial remained inconclusive. Independent replications are warranted to confirm the findings. Clinical Trial Registration Number: CTRI/2020/10/028617.

目的:坐骨神经痛是一种使人衰弱的疾病,会导致其分布区或与其相连的腰骶部神经根疼痛。虽然有顺势疗法可以减轻坐骨神经痛疼痛的说法,但目前还缺乏系统的科学证明。该试验的目的是确定个性化顺势疗法药物(IHMs)在治疗坐骨神经痛疼痛方面是否与外观相同的安慰剂一样有效。设计:这是一项双盲、随机(1:1)、两组平行、安慰剂对照试验。研究地点研究在印度西孟加拉邦豪拉的马赫什-巴塔查里亚顺势疗法医学院和医院进行。研究对象: 60 名坐骨神经痛患者:60 名坐骨神经痛患者参与了本研究。干预:Verum(n = 30;IHMs 加辅助护理)与对照组(n = 30;安慰剂加辅助护理)。结果测量:初级--坐骨神经痛烦扰指数(SBI)和坐骨神经痛频率指数(SFI)评分,中级--罗兰-莫里斯疼痛与残疾问卷(RMPDQ)、麦吉尔疼痛简表(SF-MPQ)和奥斯韦斯特里腰痛问卷(OLBPQ)评分:所有评分均在基线时测量,每月测量一次,直至 3 个月。研究结果对意向治疗样本(n = 60)进行了分析。通过双向(分半)重复测量方差分析(主要考虑组间和时间间的交互作用)和非配对 t 检验(比较每个月单独获得的估计值)来检验组间差异。显著性水平设定为 p p = 0.044)、SFI(p = 0.080)和 RMPDQ 分数(p = 0.134),但 SF-MPQ (p = 0.007)和 OLBPQ (p = 0.036)显著。多头萘醌(n = 6;10%)是最常用的处方药。两组患者均未出现任何伤害、严重不良事件或并发症。结论:主要结果未能明显证明顺势疗法的疗效优于安慰剂,试验仍未得出结论。有必要进行独立的重复试验,以确认研究结果。临床试验注册号:CTRI/2020/10/028617.
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引用次数: 0
期刊
Journal of Integrative and Complementary Medicine
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