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Mechanism of Action of Mindfulness-Based Interventions for Pain Relief-A Systematic Review. 以正念为基础的疼痛缓解干预的作用机制--系统性综述。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-12-01 Epub Date: 2024-07-23 DOI: 10.1089/jicm.2023.0328
Markus Ploesser, David Martin
<p><p><b><i>Background:</i></b> Currently, no systematic evidence synthesis of the mechanism of action of mindfulness-based approaches exists for pain conditions. <b><i>Aim:</i></b> To identify and synthesize experimental and clinical studies examining aspects of the mechanism of action of mindfulness for pain relief. <b><i>Methods:</i></b> The following databases and search interfaces were searched: Embase (via Embase.com) and Medline (via PubMed). Additional references were identified via bibliographies of included studies. The following were the inclusion criteria applied: (1) original studies published in peer-reviewed journals, (2) in adult populations that (3) examined the mechanism of action of mindfulness meditation on pain outcomes or (4) provided conclusions regarding the potential mechanism of action of mindfulness meditation. The studies were selected by two independent reviewers. Discrepancies were resolved by discussion. <b><i>Results:</i></b> A total of 21 studies published in English met the inclusion criteria, of which 5 studies were clinical studies, which included patients with chronic pain, and 16 studies used experimental pain induction. The investigation into brain mechanisms through functional magnetic resonance imaging and diffusion tensor imaging revealed mindfulness meditation's ability to modulate brain activity, particularly in the anterior cingulate cortex, anterior insula, and orbitofrontal cortex, and to enhance structural and functional connectivity in regions associated with pain perception. Regarding the role of opioids, findings across five studies indicated that the analgesic effects of mindfulness are maintained even when opioid receptors are blocked, suggesting a nonopioidergic pathway for pain modulation. Pain perception studies highlighted that mindfulness practices foster pain acceptance and modify pain control beliefs, serving as key mediators in improving pain outcomes. For experienced versus novice mindfulness practitioners, results demonstrated that long-term practice enhances pain threshold and reduces pain unpleasantness through increased activity in salience and attentional control regions. <b><i>Conclusion:</i></b> This systematic review highlights mindfulness meditation as a multifaceted approach to pain management, utilizing mechanisms such as cognitive and emotional reappraisal, nonopioidergic pathways, and enhanced attention in control regions. It emphasizes the role of mindfulness in fostering pain acceptance and altering pain control perceptions, showcasing its broad impact on the neurological and experiential dimensions of pain. However, the predominance of studies on healthy subjects and methodological variations across experiments necessitates careful interpretation of the findings. The review calls for further research to explore the mechanisms of mindfulness in chronic pain populations more deeply, distinguishing the specific effects of mindfulness from nonspecific effects and expanding
背景:目前,还没有关于正念法治疗疼痛的作用机制的系统证据综述。目的:确定并综合研究正念止痛作用机制的实验和临床研究。方法:检索以下数据库和检索界面:Embase(通过 Embase.com)和 Medline(通过 PubMed)。通过纳入研究的参考书目确定了其他参考文献。纳入标准如下:(1) 在同行评审期刊上发表的原创研究,(2) 成人人群,(3) 研究正念冥想对疼痛结果的作用机制,或 (4) 提供有关正念冥想潜在作用机制的结论。这些研究由两名独立评审员进行筛选。不一致之处通过讨论解决。结果:共有 21 项以英语发表的研究符合纳入标准,其中 5 项研究为临床研究,包括慢性疼痛患者,16 项研究使用了实验性疼痛诱导。通过功能磁共振成像和弥散张量成像对大脑机制的调查显示,正念冥想能够调节大脑活动,尤其是前扣带回皮层、前岛叶和眶额皮层的活动,并增强疼痛感知相关区域的结构和功能连接。关于阿片类药物的作用,五项研究结果表明,即使阿片受体被阻断,正念的镇痛效果也能保持,这表明疼痛调节的途径是非阿片受体的。疼痛感知研究强调,正念练习能促进对疼痛的接受并改变疼痛控制信念,是改善疼痛结果的关键媒介。对于经验丰富的正念练习者和新手,研究结果表明,长期练习可提高疼痛阈值,并通过增加突出和注意控制区域的活动来减少疼痛的不快感。结论这篇系统性综述强调了正念冥想是一种多方面的疼痛管理方法,它利用了认知和情绪重新评估、非蛛网膜通路以及控制区域注意力增强等机制。它强调了正念在促进疼痛接受度和改变疼痛控制感知方面的作用,展示了正念对疼痛的神经和体验层面的广泛影响。然而,对健康受试者的研究居多,且不同实验的方法存在差异,因此有必要对研究结果进行仔细解读。综述呼吁进一步开展研究,更深入地探索正念在慢性疼痛人群中的作用机制,区分正念的特异性作用和非特异性作用,并扩大其在慢性疼痛管理临床环境中的适用性。
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引用次数: 0
Chiropractic Services and Employment Characteristics within U.S. Federally Qualified Health Centers: Cross-Sectional Survey. 脊骨神经科服务与美国联邦合格医疗中心的就业特征:横断面调查。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-28 DOI: 10.1089/jicm.2024.0681
Andrea Albertson, Holli Kells, Charles Sawyer, Michele Maiers

Objective: Federally Qualified Health Centers (FQHCs) provide comprehensive primary care to underserved populations. While the presence of chiropractic services in these multidisciplinary systems is of growing interest, little is known. The purpose of this study is to identify and map where Doctors of Chiropractic (DCs) are employed or providing care within FQHCs and describe their employment characteristics. Methods: Websites for FQHC clinics identified by the Health Resources and Services Administration were reviewed to determine whether chiropractic services are offered and/or a DC is employed at that clinic. Identified DCs were invited to participate in a cross-sectional survey, which included questions about their employment. Analysis of survey data utilized descriptive statistics and content analysis of open-ended questions. Results: We identified 233 DCs working full- or part-time in 146 of 1537 (9.5%) FQHC systems, with two thirds of those employing more than one DC. Chiropractic services are delivered at FQHCs in 28/50 U.S. states, 75.0% of which offer a chiropractic benefit in their state Medicaid program. California had the largest concentration of FQHCs offering chiropractic services (65/146, 44.5%). Of surveys sent to 206 viable DC e-mail addresses, 101 were completed (49.0% response rate). Most DCs responded to personal (39.0%) or advertised (26.0%) solicitation for employment by the FQHC, while some DCs (14.0%) initiated the opportunity. Average employment at the FQHC was 5.1 years. Credentialing levels and compensation structures were inconsistent. DCs predominantly spend their time on clinical care (mean 88.0%) compared with administrative tasks (mean 10.4%). Conclusion: This study provides important baseline information about the presence of chiropractic within FQHCs and DCs employment characteristics. Future research should include exploring the roles DCs fulfill within FQHCs, skills necessary for successful collaboration, and barriers to incorporating chiropractic services within these systems.

目标:联邦合格医疗中心(FQHC)为医疗服务不足的人群提供全面的初级医疗服务。尽管脊骨神经科服务在这些多学科系统中的存在日益受到关注,但人们对此知之甚少。本研究旨在确定并绘制脊骨神经科医生(DC)受雇于联邦合格医疗中心或在其中提供医疗服务的地点,并描述他们的就业特点。研究方法:对卫生资源与服务管理局确定的联邦紧急健康服务中心诊所的网站进行审查,以确定该诊所是否提供脊骨神经科服务和/或是否聘用了脊骨神经科医生。已确定的脊骨神经科医生被邀请参加一项横断面调查,其中包括有关其就业情况的问题。调查数据的分析采用了描述性统计和开放式问题的内容分析。结果:我们在 1537 家 FQHC 系统中的 146 家(9.5%)确定了 233 名全职或兼职的脊骨神经科医生,其中三分之二聘用了一名以上的脊骨神经科医生。美国50个州中有28个州的FQHC提供脊骨神经治疗服务,其中75.0%的州在本州医疗补助计划中提供脊骨神经治疗补助。加利福尼亚州提供脊骨神经治疗服务的FQHC最多(65/146,44.5%)。在发送到 206 个可行的脊骨神经科医生电子邮件地址的调查问卷中,有 101 份完成(回复率为 49.0%)。大多数区医生都是通过个人(39.0%)或广告(26.0%)的方式对家庭保健中心的招聘广告做出了回应,也有一些区医生(14.0%)主动寻求就业机会。在家庭健康服务中心的平均工作年限为 5.1 年。资历水平和报酬结构不一致。与行政工作(平均 10.4%)相比,门诊医生主要将时间用于临床护理(平均 88.0%)。结论本研究提供了有关脊骨神经科在联邦定点医疗机构中的存在情况以及脊骨神经科医生就业特点的重要基线信息。未来的研究应包括探讨脊骨神经科医生在家庭健康服务中心中扮演的角色、成功合作所需的技能以及将脊骨神经科服务纳入这些系统的障碍。
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引用次数: 0
Is Acupuncture an Effective Treatment for Radiation-Induced Xerostomia of Patients with Head and Neck Cancer? A Systematic Review and Meta-Analysis. 针灸是否能有效治疗头颈部癌症患者的放射性口腔溃疡?系统回顾与元分析》。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-26 DOI: 10.1089/jicm.2023.0781
Wenzhe Gu, Hongjun Dong, Yuan Yuan, Zijiang Yuan, Xiaoting Jiang, Yuhan Qian, Zhengjie Shen

Background: Radiation-induced xerostomia (RIX) stands out as one of the most severe side effects among patients with head and neck cancer (HNC). Given the varied conclusions in previous studies concerning the association between acupuncture, sham acupuncture, or acupuncture combined with standard oral care and therapeutic effects, our aim is to conduct a systematic review to assess the effectiveness and safety of acupuncture in managing RIX in patients with HNC. Methods: Six databases (Cochrane Library, PubMed, EMBASE, China National Knowledge Infrastructure, Chongqing VIP, and WanFang Database) were electronically searched, following the Cochrane manual and adhering to reported Preferred Reporting Item for Systematic Reviews and Meta-Analyses guidelines, from their inception dates to July 1, 2024. Primary randomized clinical trials included in systematic reviews or meta-analyses were identified, with the Xerostomia Questionnaire and Xerostomia Inventory designated as the primary outcomes. Salivary flow rates (unstimulated or stimulated) were defined as secondary outcomes. Results: Eight clinical trials involving 1273 participants were analyzed, with six studies included in the meta-analysis. The results indicate that acupuncture demonstrated a significant improvement in patient-reported xerostomia scores (standardized mean difference [SMD] = -0.20, 95% confidence interval [95% CI] [-0.38, -0.02], I2 = 0%) in comparison to standard care, but did not significantly improve oral dryness symptoms compared with sham acupuncture (SMD = -0.06, 95% CI [-0.29, 0.16], I2 = 25.8%). The merged total showed negative result (SMD = -0.13, 95% CI [-0.27, 0.01], I2 = 8.2%). Additionally, there was no significant difference in stimulated salivary flow rate (SMD = -0.22, 95% CI [-0.58, 0.13], I2 = 0%) and unstimulated salivary flow rate (SMD = -0.19, 95% CI [-0.11, 0.72], I2 = 67.2%). In general, the acupuncture did not cause serious adverse effects. Conclusion: As far as current research is concerned, acupuncture treatment for RIX symptoms in patients with HNC still lacks strong and convincing evidence support. The more scientific research methods and more clinical trials are still needed.

背景:放射引起的口腔干燥症(RIX)是头颈部癌症(HNC)患者最严重的副作用之一。鉴于之前的研究对针灸、假针灸或针灸结合标准口腔护理与治疗效果之间的关联得出了不同的结论,我们的目的是进行一项系统性综述,以评估针灸治疗 HNC 患者 RIX 的有效性和安全性。研究方法按照 Cochrane 手册并遵照所报告的《系统综述和元分析首选报告项目》指南,对六个数据库(Cochrane 图书馆、PubMed、EMBASE、中国国家知识基础设施、重庆 VIP 和万方数据库)进行了电子检索,检索时间从开始日期到 2024 年 7 月 1 日。确定了系统综述或荟萃分析中包含的主要随机临床试验,并将口腔干燥症问卷和口腔干燥症量表指定为主要结果。唾液流速(非刺激性或刺激性)被定义为次要结果。研究结果对涉及 1273 名参与者的 8 项临床试验进行了分析,其中 6 项研究纳入了荟萃分析。结果表明,与标准护理相比,针灸显著改善了患者报告的口腔干燥评分(标准化平均差 [SMD] = -0.20,95% 置信区间 [95% CI] [-0.38, -0.02],I2 = 0%),但与假针灸相比,针灸并未显著改善口腔干燥症状(SMD = -0.06,95% CI [-0.29, 0.16],I2 = 25.8%)。合并总结果显示为负值(SMD = -0.13,95% CI [-0.27,0.01],I2 = 8.2%)。此外,刺激性唾液流量(SMD = -0.22,95% CI [-0.58,0.13],I2 = 0%)和非刺激性唾液流量(SMD = -0.19,95% CI [-0.11,0.72],I2 = 67.2%)无显著差异。总的来说,针灸没有引起严重的不良反应。结论就目前的研究而言,针灸治疗 HNC 患者的 RIX 症状仍缺乏有力和令人信服的证据支持。还需要更科学的研究方法和更多的临床试验。
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引用次数: 0
Barriers and Facilitators to the Inclusion of Naturopaths in Interprofessional Health Care Teams: A Scoping Review. 将自然疗法师纳入跨专业医疗团队的障碍和促进因素:范围界定综述》。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-26 DOI: 10.1089/jicm.2024.0569
Isabelle Taye, Sandra Grace, Joanne Bradbury

Objective: The growing population of individuals with chronic pain presents a challenge to a globally overburdened health care workforce. Naturopaths are trained as primary health care providers who manage patients with chronic pain and, yet, are often overlooked in health care teams. This scoping review aims to identify barriers and facilitators affecting naturopathic inclusion into interprofessional health care teams managing patients with chronic pain. Methods: This study protocol was registered a priori through Open Science (https://doi.org/10.17605/OSF.IO/2G3JT). A search was conducted using databases AMED, CINAHL, MEDLINE, SCOPUS, Web of Science, APA PsycInfo, and Health Business Elite. Search limits included English language from 2012 to 2023. Included publications were from academic and gray literature. Search terms used included the following: "Naturopath*" OR "Integrative medicine" AND "Health care system*" OR "Health system*" OR "Models of health care" OR "Professional autonomy" OR "Professional regulation" OR "Professional govern*" OR "Interprofessional practice (IPP)" OR "Multidisciplinary communication." The scoping review utilized Covidence software and was analyzed using thematic analysis. Themes were identified following Arksey and O'Malley's (2005) framework to inform a narrative approach. Results: Five themes emerged that relate to the inclusion of naturopaths in health care teams as follows: (1) perceptions of naturopathy, (2) practice standards, (3) legitimacy, (4) resources, and (5) shifting power dynamics and cooperation. Conclusions: Barriers for naturopathic inclusion into health care teams are influenced by perceptions of naturopathy, naturopathic education standards, regulations, research, and patient equity and access. Facilitators for inclusion include the growing shift toward person-centered care, greater interprofessional education, and shared assets, including colocation.

目的:越来越多的人患有慢性疼痛,这给全球负担过重的医疗队伍带来了挑战。自然疗法师被培训为初级医疗保健提供者,负责管理慢性疼痛患者,但在医疗保健团队中却经常被忽视。本范围界定综述旨在找出影响自然疗法融入跨专业医护团队、管理慢性疼痛患者的障碍和促进因素。研究方法本研究方案事先已通过开放科学(https://doi.org/10.17605/OSF.IO/2G3JT)进行了注册。使用 AMED、CINAHL、MEDLINE、SCOPUS、Web of Science、APA PsycInfo 和 Health Business Elite 等数据库进行了检索。搜索范围包括 2012 年至 2023 年的英文文献。纳入的出版物来自学术和灰色文献。使用的搜索关键词包括"自然疗法或 "整合医学 "和 "医疗保健系统*"或 "卫生系统*"或 "医疗保健模式 "或 "专业自治 "或 "专业监管 "或 "专业管理*"或 "跨专业实践(IPP)"或 "多学科交流"。范围界定审查使用 Covidence 软件,并采用专题分析法进行分析。根据 Arksey 和 O'Malley(2005 年)的框架确定了主题,为叙事方法提供了依据。结果:与将自然疗法师纳入医疗团队有关的五个主题如下:(1) 对自然疗法的看法,(2) 实践标准,(3) 合法性,(4) 资源,以及 (5) 权力动态变化与合作。结论:将自然疗法纳入医疗团队的障碍受到对自然疗法的看法、自然疗法教育标准、法规、研究以及患者公平性和可及性的影响。促进自然疗法融入医疗保健团队的因素包括:日益转向以人为本的医疗保健、更多的跨专业教育以及共享资产(包括同地办公)。
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引用次数: 0
Piloting an Educational Approach to Assess eHealth Literacy and Evidence-Based Medicine in Integrative Health: A Feasibility and Validation Study. 试行一种教育方法来评估综合保健中的电子保健素养和循证医学:可行性和验证研究。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-26 DOI: 10.1089/jicm.2024.0594
Daryl Nault, Atiera Abatemarco, Marybeth Missenda, Christine Cherpak-Castagna, Steffany Moonaz

Introduction: Low rates of online health literacy put consumers at risk of misinformation, but this could be mitigated through practitioner engagement. Integrative health (IH) crosses health care disciplines, so it is well-positioned to improve health information sharing. IH practitioners require evidence-based medicine (EBM) and electronic health literacy (eHL) competencies to make such impact. Several EBM assessments exist, but none are IH-specific. The Fresno Test of EBM FEBM is a validated, performance-based assessment used in medical education. We sought to assess feasibility of incorporating eHL and EBM assessments into graduate coursework while adapting and validating the FEBM for an IH audience (FEBM-IH). Methods: A pilot observational design was used to adapt, evaluate, administer, and validate the FEBM-IH. Revalidation of the FEBM-IH began with a discipline-focused adaptation, which was reviewed by an expert panel. The FEBM-IH was then administered to IH students and faculty. Independently scored assessments determined inter-rater reliability, internal consistency, item discrimination, and item difficulty. eHL assessments (eHEALS and General Health Numeracy Test-6) were also embedded in the online course. Results: Outcome completion rates suggest the FEBM-IH and eHL assessment tools are feasible to include in online courses, with 68.9% (102/148) eligible participants joining and 76.5% (78/102) completing all questions in all measures. The FEBM-IH demonstrated excellent assessor agreement (kappa = 0.97, p < 0.001), high internal consistency (α = 0.799), and acceptable item discrimination (0.26-0.68). Median self-perceived eHL scores increased from 30/40 to 33/40 points by course's end, suggesting some increase in eHL. Conclusions: Tools were feasible to integrate; FEBM-IH maintains acceptable validity; and further exploration of the relationship between EBM and eHL is warranted.

导言:低在线健康知识普及率使消费者面临信息错误的风险,但这可以通过从业人员的参与得到缓解。整合医疗(IH)跨越了医疗保健的各个学科,因此在改善健康信息共享方面具有得天独厚的优势。整合保健从业人员需要具备循证医学(EBM)和电子健康知识(eHL)能力,才能发挥这种影响。目前已有几种循证医学评估方法,但没有一种是专门针对 IH 的。Fresno Test of EBM FEBM 是一项经过验证的、基于表现的评估,用于医学教育。我们试图评估将 eHL 和 EBM 评估纳入研究生课程的可行性,同时针对 IH 受众调整和验证 FEBM(FEBM-IH)。方法:采用试点观察设计来调整、评估、管理和验证 FEBM-IH。对 FEBM-IH 的重新验证首先是进行以学科为重点的改编,并由专家小组进行审查。然后,对 IH 的学生和教师进行了 FEBM-IH 测试。独立评分的评估确定了评分者之间的可靠性、内部一致性、项目区分度和项目难度。eHL评估(eHEALS和General Health Numeracy Test-6)也被嵌入到在线课程中。结果结果完成率表明,将 FEBM-IH 和 eHL 评估工具纳入在线课程是可行的,68.9%(102/148)符合条件的学员参加了在线课程,76.5%(78/102)的学员完成了所有测评项目的所有问题。FEBM-IH显示了极好的评估者一致性(kappa = 0.97,p < 0.001)、高内部一致性(α = 0.799)和可接受的项目区分度(0.26-0.68)。到课程结束时,自我感觉的 eHL 分数中位数从 30/40 分增加到 33/40 分,表明 eHL 有了一定程度的提高。结论:整合工具是可行的;FEBM-IH 保持了可接受的有效性;EBM 和 eHL 之间的关系值得进一步探讨。
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引用次数: 0
A Scoping Review on Clinical Research of Acupuncture Treatment for Pressure Injury. 针灸治疗压力性损伤临床研究范围界定综述
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-26 DOI: 10.1089/jicm.2024.0695
Hengjing Zhu, Yingqi Xu, Rongrong Hu, Jinlan Jiang, Ruxuan Zhang, Xiaoqing Jin

Objective: Acupuncture is a traditional Chinese medical therapy that has shown effective results in the treatment of pressure injuries (PI). However, current clinical research methodologies have certain flaws that impact the evaluation of efficacy. This review aims to summarize the characteristics of existing clinical studies on acupuncture treatment for PI and analyze the current research status. Methods: Following the research methodology for scoping reviews, databases, including CNKI, Wanfang Data, China Biology Medicine, Web of Science, PubMed, EMBASE, and Cochrane Library, were searched. The search period covered from the inception of the databases up to February 22, 2024. The studies included were screened, summarized, and analyzed, extracting data from three aspects as follows: bibliometric data, patient information, and research design. Results: A total of 46 clinical studies were included. These comprised 30 randomized controlled trials (RCTs), 11 case series, 2 case reports, and 3 controlled clinical trials. Filiform needle therapy was the most commonly used acupuncture technique. Acupuncture is basically performed locally on the wound surface. The clinical efficacy rate was the most frequently used outcome measure. Conclusions: Clinical studies on acupuncture for PI have issues such as nonstandard selection and reporting of outcomes, inconsistent indicator evaluation tools, and unclear concept of "randomization" in RCTs. These factors lead to significant heterogeneity among studies, affecting the assessment of treatment efficacy. Future research should strictly standardize the design and reporting of RCTs and promote the establishment of core outcome sets for acupuncture treatment of PI, to enhance the evidence quality of acupuncture clinical research.

目的:针灸是一种传统中医疗法,在治疗压力性损伤(PI)方面效果显著。然而,目前的临床研究方法存在一定缺陷,影响了疗效评估。本综述旨在总结现有针灸治疗压力性损伤临床研究的特点,并分析其研究现状。研究方法按照范围综述的研究方法,检索了 CNKI、万方数据、中国生物医学、Web of Science、PubMed、EMBASE 和 Cochrane Library 等数据库。检索期从数据库建立之初至 2024 年 2 月 22 日。对纳入的研究进行筛选、汇总和分析,从以下三个方面提取数据:文献计量学数据、患者信息和研究设计。结果:共纳入 46 项临床研究。其中包括 30 项随机对照试验 (RCT)、11 项病例系列、2 项病例报告和 3 项临床对照试验。丝状针疗法是最常用的针灸技术。针灸基本上是在伤口表面局部进行。临床有效率是最常用的结果衡量标准。结论针灸治疗 PI 的临床研究存在一些问题,如结果的选择和报告不规范、指标评价工具不一致、RCT 中 "随机化 "的概念不明确等。这些因素导致研究之间存在明显的异质性,影响了疗效的评估。今后的研究应严格规范RCT的设计和报告,推动建立针刺治疗PI的核心结果集,提高针刺临床研究的证据质量。
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引用次数: 0
"It Has Improved My Practice to Be Able to Offer Alternative Treatments": A Longitudinal Qualitative Study of Oregon Medicaid Back Pain Providers. "能够提供替代疗法改善了我的工作":俄勒冈州医疗补助背痛提供者纵向定性研究》。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-07-08 DOI: 10.1089/jicm.2023.0743
Mary Gray, Alexis Cooke, Catherine J Livingston, Kate LaForge, Diana P Flores, Esther K Choo

Introduction: This study aimed to understand health care providers' experiences implementing the Oregon Back Pain Policy (OBPP) over time. The Medicaid OBPP expanded coverage of evidence-based nonpharmacological therapy (NPT) for back pain and restricted access to opioid therapy and interventional approaches. Methods: The study included six online, asynchronous focus groups with providers in February 2020 (Time 1) and August 2022 (Time 2). Analysis was conducted with a longitudinal, recurrent cross-sectional approach. Analysis occurred in three stages: (1) An immersion/crystallization approach was used to analyze Time 1 focus group data, (2) reflexive thematic analysis was used to analyze Time 2 data, and (3) longitudinal analysis was used to integrate the findings across time points. Results: At Time 1, 48 clinicians and 44 NPT providers participated in the study. Time 2 included 63 clinicians and 59 NPT providers. The longitudinal analysis of the focus group data resulted in four themes: (1) general awareness of the policy, (2) providers support the policy and perceive a benefit to their patients, (3) barriers to NPT accessibility, and (4) barriers to referring patients to NPT. Conclusion: The goal of the OBPP was to improve back pain care for Oregon Medicaid members by increasing access to evidence-based NPT and decreasing reliance on opioid medications. This study revealed that, although clinicians and NPT providers supported the policy, they faced persistent implementation challenges related to referrals, prior authorizations, coverage limitations, low reimbursement rates, and a reduced workforce for NPT providers. In some cases, implementation barriers were removed during the COVID-19 pandemic, but other challenges were more prominent during the pandemic.

简介:本研究旨在了解医疗服务提供者在实施俄勒冈背痛政策(OBPP)过程中的经验。俄勒冈背痛政策》扩大了背痛循证非药物疗法 (NPT) 的覆盖范围,并限制了阿片类药物疗法和介入疗法的使用。研究方法:研究包括与医疗服务提供者在 2020 年 2 月(时间 1)和 2022 年 8 月(时间 2)进行的六次在线异步焦点小组讨论。分析采用纵向、重复横截面方法进行。分析分为三个阶段:(1) 采用沉浸/结晶法分析时间 1 的焦点小组数据,(2) 采用反思性专题分析法分析时间 2 的数据,(3) 采用纵向分析法整合各时间点的研究结果。结果:在时间 1,48 名临床医生和 44 名 NPT 提供者参与了研究。时间 2 包括 63 名临床医生和 59 名 NPT 提供者。对焦点小组数据的纵向分析产生了四个主题:(1) 对该政策的普遍认识,(2) 提供者支持该政策并认为对其患者有益,(3) NPT 可及性的障碍,以及 (4) 将患者转诊至 NPT 的障碍。结论:OBPP 的目标是通过提高循证 NPT 的可及性,减少对阿片类药物的依赖,从而改善俄勒冈州医疗补助成员的背痛护理。本研究表明,尽管临床医生和 NPT 提供者支持该政策,但他们在实施过程中仍面临转诊、事先授权、承保范围限制、报销率低以及 NPT 提供者劳动力减少等方面的挑战。在某些情况下,执行障碍在 COVID-19 大流行期间得以消除,但其他挑战在大流行期间则更为突出。
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引用次数: 0
The Timing and Dose Effect of Acupuncture on Pregnancy Outcomes for Infertile Women Undergoing In Vitro Fertilization and Embryo Transfer: A Systematic Review and Meta-Analysis. 针灸对接受体外受精和胚胎移植的不孕妇女妊娠结果的时间和剂量效应:系统回顾与元分析》。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-05-29 DOI: 10.1089/jicm.2023.0478
Xia Wang, Hong-Mei Xu, Qiao-Ling Wang, Xin-Yun Zhu, Ya-Min Zeng, Li Huang, Xin Feng, Shuai Chen

Background: Women undergoing in vitro fertilization and embryo transfer (IVF-ET) often utilize acupuncture to enhance pregnancy outcomes. Yet, the optimal timing for acupuncture sessions and the relationship between dosage and effect remain uncertain. Objectives: To investigate the impact of the timing and dosage of acupuncture on pregnancy outcomes, drawing on existing research. Methods: A comprehensive search of eight databases was conducted from their inception to January 14th, 2023, without restrictions on language. Only randomized controlled trials comparing acupuncture with either sham acupuncture or no adjuvant treatment were selected for inclusion. This meta-analysis assessed the efficacy of acupuncture in IVF-ET, analyzing the influence of varied timing and dosage on pregnancy outcomes. Subgroup analyses were undertaken to address any heterogeneity across the studies. Results: A total of 38 RCTs involving 5,991 participants were analyzed. In infertile women undergoing IVF fresh cycles, acupuncture performed during controlled ovarian hyperstimulation (COH) significantly increased the clinical pregnancy rate (CPR) (relative risk [RR] = 1.33, 95% confidence interval [CI]: 1.07-1.65, p = 0.01), whereas acupuncture administered either before COH or on the day of ET did not demonstrate reproductive benefits. Regarding frozen cycles, acupuncture before freeze-thaw embryo transfer (FET) significantly enhanced the CPR (RR = 1.71, 95% CI: 1.36-2.16, p < 0.00001) and live birth rate (LBR) (RR = 2.40, 95% CI: 1.20-4.79, p = 0.01). Improvements in CPR were observed across all dosage groups, but only the high-dosage group showed a significant increase in LBR (RR = 1.75, 95% CI: 1.05-2.92, p = 0.03). Conclusions: Timing and dosage of acupuncture are crucial factors affecting pregnancy outcomes in IVF-ET. For women undergoing IVF fresh cycles, acupuncture during COH yielded more significant reproductive benefits. In addition, acupuncture before freeze-thaw embryo transfer (FET) was associated with improved pregnancy outcomes in frozen cycles. Furthermore, higher dosages of acupuncture were linked to more favorable outcomes.

背景:接受体外受精和胚胎移植(IVF-ET)的妇女经常利用针灸来提高妊娠效果。然而,针灸治疗的最佳时间以及剂量与效果之间的关系仍不确定。研究目的借鉴现有研究,调查针灸时间和剂量对妊娠结局的影响。方法:对八个数据库进行全面检索:对八个数据库进行了全面检索,检索时间从数据库建立之初至 2023 年 1 月 14 日,检索语言不限。只有将针灸与假针灸或无辅助治疗进行比较的随机对照试验才被选入。这项荟萃分析评估了针灸在体外受精-胚胎移植中的疗效,分析了不同时间和剂量对妊娠结果的影响。针对各项研究中存在的异质性,还进行了分组分析。研究结果共分析了 38 项研究,涉及 5991 名参与者。在接受试管婴儿新周期治疗的不孕妇女中,在控制性卵巢过度刺激(COH)期间进行针灸可显著提高临床妊娠率(CPR)(相对风险 [RR] = 1.33,95% 置信区间 [CI]:1.07-1.65,P<0.05):相对风险 [RR] = 1.33,95% 置信区间 [CI]:1.07-1.65,P = 0.01),而在 COH 之前或 ET 当日进行针灸并未显示出生殖益处。在冷冻周期中,冻融胚胎移植(FET)前针灸可显著提高 CPR(RR = 1.71,95% CI:1.36-2.16,p < 0.00001)和活产率(LBR)(RR = 2.40,95% CI:1.20-4.79,p = 0.01)。所有剂量组的 CPR 均有改善,但只有高剂量组的 LBR 有显著提高(RR = 1.75,95% CI:1.05-2.92,p = 0.03)。结论针灸的时间和剂量是影响 IVF-ET 妊娠结局的关键因素。对于接受试管婴儿新鲜周期的妇女来说,在COH期间进行针灸可获得更显著的生殖益处。此外,在冻融胚胎移植(FET)前进行针灸与改善冷冻周期的妊娠结局有关。此外,针灸剂量越大,效果越好。
{"title":"The Timing and Dose Effect of Acupuncture on Pregnancy Outcomes for Infertile Women Undergoing <i>In Vitro</i> Fertilization and Embryo Transfer: A Systematic Review and Meta-Analysis.","authors":"Xia Wang, Hong-Mei Xu, Qiao-Ling Wang, Xin-Yun Zhu, Ya-Min Zeng, Li Huang, Xin Feng, Shuai Chen","doi":"10.1089/jicm.2023.0478","DOIUrl":"10.1089/jicm.2023.0478","url":null,"abstract":"<p><p><b><i>Background:</i></b> Women undergoing <i>in vitro</i> fertilization and embryo transfer (IVF-ET) often utilize acupuncture to enhance pregnancy outcomes. Yet, the optimal timing for acupuncture sessions and the relationship between dosage and effect remain uncertain. <b><i>Objectives:</i></b> To investigate the impact of the timing and dosage of acupuncture on pregnancy outcomes, drawing on existing research. <b><i>Methods:</i></b> A comprehensive search of eight databases was conducted from their inception to January 14th, 2023, without restrictions on language. Only randomized controlled trials comparing acupuncture with either sham acupuncture or no adjuvant treatment were selected for inclusion. This meta-analysis assessed the efficacy of acupuncture in IVF-ET, analyzing the influence of varied timing and dosage on pregnancy outcomes. Subgroup analyses were undertaken to address any heterogeneity across the studies. <b><i>Results:</i></b> A total of 38 RCTs involving 5,991 participants were analyzed. In infertile women undergoing IVF fresh cycles, acupuncture performed during controlled ovarian hyperstimulation (COH) significantly increased the clinical pregnancy rate (CPR) (relative risk [RR] = 1.33, 95% confidence interval [CI]: 1.07-1.65, <i>p</i> = 0.01), whereas acupuncture administered either before COH or on the day of ET did not demonstrate reproductive benefits. Regarding frozen cycles, acupuncture before freeze-thaw embryo transfer (FET) significantly enhanced the CPR (RR = 1.71, 95% CI: 1.36-2.16, <i>p</i> < 0.00001) and live birth rate (LBR) (RR = 2.40, 95% CI: 1.20-4.79, <i>p</i> = 0.01). Improvements in CPR were observed across all dosage groups, but only the high-dosage group showed a significant increase in LBR (RR = 1.75, 95% CI: 1.05-2.92, <i>p</i> = 0.03). <b><i>Conclusions:</i></b> Timing and dosage of acupuncture are crucial factors affecting pregnancy outcomes in IVF-ET. For women undergoing IVF fresh cycles, acupuncture during COH yielded more significant reproductive benefits. In addition, acupuncture before freeze-thaw embryo transfer (FET) was associated with improved pregnancy outcomes in frozen cycles. Furthermore, higher dosages of acupuncture were linked to more favorable outcomes.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1031-1046"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ginger for Pain Management in Primary Dysmenorrhea: A Systematic Review and Meta-Analysis. 生姜治疗原发性痛经:系统回顾与元分析》。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-05-21 DOI: 10.1089/jicm.2023.0799
Reza Moshfeghinia, Nastaran Salmanpour, Hamed Ghoshouni, Hossein Gharedaghi, Roghayeh Zare, Holger Cramer, Ghazaleh Heydarirad, Mehdi Pasalar

Background: Primary dysmenorrhea is a common gynecological disorder that affects many women of reproductive age. Ginger, a widely used spice with anti-inflammatory properties, has been suggested as a potential treatment for the painful cramps associated with this condition. Objective: The aim of this systematic review and meta-analysis was to evaluate the efficacy of ginger for pain management in primary dysmenorrhea. Methods: Our systematic review was registered in Prospero (CRD42023418001). Six English (PubMed, Scopus, Web of Science, PsycINFO, CINAHL complete, and Cochrane) and one Persian electric database (SID) was searched up to May 2023 for English or Persian studies that measure the effect of ginger on pain in dysmenorrhea. The Cochrane tool was used to assess the risk of bias of the included studies. Random effects meta-analyses were performed to obtain standardized mean differences (SMD) and 95% confidence intervals (CI). Results: Out of the 804 articles initially identified from the search, 24 were included for qualitative analysis and 12 for quantitative analysis after a full-text evaluation. The combined results of the studies indicate that ginger is notably more effective than placebo in reducing both the intensity (SMD = -1.13; 95% CI = -1.59 to -0.68, I2 = 81.05%) and duration of pain (SMD = -0.29; 95% CI = -0.46 to -0.12). There were no differences between ginger and nonsteroidal anti-inflammatory drugs (NSAIDs) (SMD = 0.01; 95% CI = -0.24 to 0.25), or exercise (SMD = 0.06; 95% CI = -0.66 to 0.78) for pain intensity. Safety-related data were infrequently reported. Conclusions: The results of this meta-analysis suggest that ginger can effectively reduce pain associated with dysmenorrhea. The findings are limited due to risk of bias in the included studies and the unclear risk-benefit ratio.

背景:原发性痛经是一种常见的妇科疾病,影响着许多育龄妇女。生姜是一种广泛使用的香料,具有抗炎特性,被认为是治疗与这种疾病相关的痛经的一种潜在方法。目的:本系统综述和荟萃分析旨在评估生姜治疗原发性痛经疼痛的疗效。方法:我们的系统综述已在 Proceedings & Research 期刊上发表:我们的系统综述已在 Prospero(CRD42023418001)上注册。截至 2023 年 5 月,我们检索了 6 个英文数据库(PubMed、Scopus、Web of Science、PsycINFO、CINAHL complete 和 Cochrane)和 1 个波斯文电子数据库(SID),以了解生姜对痛经疼痛疗效的英文或波斯文研究。科克伦工具用于评估纳入研究的偏倚风险。通过随机效应荟萃分析得出标准化平均差 (SMD) 和 95% 置信区间 (CI)。研究结果在搜索初步确定的 804 篇文章中,经过全文评估,有 24 篇文章被纳入定性分析,12 篇文章被纳入定量分析。综合研究结果表明,生姜在降低疼痛强度(SMD = -1.13; 95% CI = -1.59 to -0.68,I2 = 81.05%)和缩短疼痛持续时间(SMD = -0.29; 95% CI = -0.46 to -0.12)方面的效果明显优于安慰剂。生姜和非甾体抗炎药(NSAIDs)(SMD = 0.01;95% CI = -0.24至0.25)或运动(SMD = 0.06;95% CI = -0.66至0.78)在疼痛强度方面没有差异。与安全相关的数据很少报道。结论这项荟萃分析的结果表明,生姜能有效减轻痛经引起的疼痛。由于纳入的研究存在偏倚风险,且风险效益比不明确,因此研究结果具有局限性。
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引用次数: 0
The Potential for Digital Phenotyping in Understanding Mindfulness App Engagement Patterns: A Pilot Study. 数字表型在了解正念应用程序参与模式方面的潜力:试点研究。
IF 1.3 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-11-01 Epub Date: 2024-06-05 DOI: 10.1089/jicm.2023.0698
Lucy Gray, Natalia Marcynikola, Ian Barnett, John Torous

Background: Low app engagement is a central barrier to digital mental health efficacy. With mindfulness-based mental health apps growing in popularity, there is a need for new understanding of factors influencing engagement. This study utilized digital phenotyping to understand real-time patterns of engagement around app-based mindfulness. Different engagement metrics are presented that measure both the total number of app-based activities participants completed each week, as well as the proportion of days that participants engaged with the app each week. Method: Data were derived from two iterations of a four-week study exploring app engagement in college students (n = 169). This secondary analysis investigated the relationships between general and mindfulness-based app engagement with passive data metrics (sleep duration, home time, and screen duration) at a weekly level, as well as the relationship between demographics and engagement. Additional clinically focused analysis was performed on three case studies of participants with high mindfulness activity completion. Results: Demographic variables such as gender, race/ethnicity, and age lacked a significant association with mindfulness app-based engagement. Passive data variables such as sleep and screen duration were significant predictors for different metrics of general and mindfulness-based app engagement at a weekly level. There was a significant interaction effect for screen duration between the number of mindfulness activities completed and whether or not the participant received a mindfulness notification. K-means clusters analyses using passive data features to predict mindfulness activity completion had low performance. Conclusions: While there are no simple solutions to predicting engagement with mindfulness apps, utilizing digital phenotyping approaches at a population and personal level offers new potential. The signal from digital phenotyping warrants more investigation; even small increases in engagement with mindfulness apps may have a tremendous impact given their already high prevalence of engagement, availability, and potential to engage patients across demographics.

背景:应用程序参与度低是数字心理健康功效的主要障碍。随着基于正念的心理健康应用程序越来越受欢迎,我们需要对影响参与度的因素有新的认识。本研究利用数字表型来了解基于应用程序的正念的实时参与模式。研究提出了不同的参与度指标,衡量参与者每周完成的基于应用程序的活动总数,以及参与者每周使用应用程序的天数比例。方法:数据来源于一项为期四周的研究的两次迭代,该研究探讨了大学生(n = 169)的应用程序参与度。这项二次分析调查了一般和正念应用程序参与度与每周被动数据指标(睡眠时长、在家时间和屏幕时长)之间的关系,以及人口统计学与参与度之间的关系。此外,还对正念活动完成度较高的三位参与者进行了临床重点分析。研究结果性别、种族/民族和年龄等人口统计学变量与正念应用程序的参与度之间没有显著关联。被动数据变量(如睡眠和屏幕持续时间)对每周的一般和正念应用程序参与度的不同指标具有显著的预测作用。完成正念活动的数量与参与者是否收到正念通知之间的屏幕持续时间存在明显的交互效应。使用被动数据特征来预测正念活动完成情况的 K-means 聚类分析效果不佳。结论:虽然没有简单的解决方案来预测正念应用程序的参与度,但在人群和个人层面利用数字表型方法提供了新的潜力。来自数字表型的信号值得进行更多研究;考虑到正念应用程序的参与率已经很高,其可用性和吸引不同人群患者参与的潜力,即使是正念应用程序参与率的微小增长也可能产生巨大影响。
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引用次数: 0
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