Alain Toledano, Solange Arnaud, Marc Bollet, Hanah Lamallem, Olivier Bauduceau, Ilan Darmon, Hanene Boudabous, Nathaniel Scher
Background: Complementary and integrative medicine (CIM) encompasses over 400 modalities, according to the World Health Organization (WHO). In 2011, 70% of the European Union's population reported having used CIM at least once, with 25% using it annually. This study examines the engagement, motivations, and satisfaction of users in the French health care system through data from Medoucine, France's largest online platform for complementary therapies. Methods: A cross-sectional descriptive analysis was conducted using Medoucine's database from 2017 to 2023, adhering to the Strengthening the Reporting of Observational Studies in Epidemiology guidelines. Data were sourced from practitioner profiles, appointment logs, and patient comments collected at baseline (day 0, J0) and follow-up (day 30, J30). Survey questions, including "What type of complementary therapy are you seeking?" provided clarity on how CIM therapies were introduced. The study included a "recommendation question" at baseline to evaluate satisfaction: "Would you recommend this practitioner to your friends and family?". Response rates varied between 10% and 67%, depending on the question. Categorical variables were analyzed as percentages. Results: Among 225,251 platform users, 67.7% (152,464) responded to the recommendation question at J0, 15% (33,823) reported health improvements at J30, and 10% (22,596) discovered sustainable health strategies. Most users were women (68.6%). Key motivations included well-being and personal development (17.4%), stress, anxiety, and phobias (17.1%), and sleep disorders (7%). Hypnosis (15%), traditional Chinese medicine (8.4%), and reflexology (6.7%) were the most commonly selected modalities. At J30, 74.8% reported health improvements, with notable benefits for well-being (80.7%) and stress (76.3%). Conclusion: This study underscores the growing demand for CIM therapies in France, driven by a need for stress relief, personal development, and physical and psychological health management. High satisfaction rates and perceived health benefits highlight the potential of CIM to complement conventional care. Integrating evidence-based CIM into mainstream health care systems, as recommended by the WHO, offers an opportunity to address patient needs and enhance health care delivery.
{"title":"Populational Uses of Complementary Therapies via a Digital Platform in France: Motivations and Needs.","authors":"Alain Toledano, Solange Arnaud, Marc Bollet, Hanah Lamallem, Olivier Bauduceau, Ilan Darmon, Hanene Boudabous, Nathaniel Scher","doi":"10.1089/jicm.2024.0519","DOIUrl":"https://doi.org/10.1089/jicm.2024.0519","url":null,"abstract":"<p><p><b><i>Background:</i></b> Complementary and integrative medicine (CIM) encompasses over 400 modalities, according to the World Health Organization (WHO). In 2011, 70% of the European Union's population reported having used CIM at least once, with 25% using it annually. This study examines the engagement, motivations, and satisfaction of users in the French health care system through data from Medoucine, France's largest online platform for complementary therapies. <b><i>Methods:</i></b> A cross-sectional descriptive analysis was conducted using Medoucine's database from 2017 to 2023, adhering to the Strengthening the Reporting of Observational Studies in Epidemiology guidelines. Data were sourced from practitioner profiles, appointment logs, and patient comments collected at baseline (day 0, J0) and follow-up (day 30, J30). Survey questions, including \"What type of complementary therapy are you seeking?\" provided clarity on how CIM therapies were introduced. The study included a \"recommendation question\" at baseline to evaluate satisfaction: \"Would you recommend this practitioner to your friends and family?\". Response rates varied between 10% and 67%, depending on the question. Categorical variables were analyzed as percentages. <b><i>Results:</i></b> Among 225,251 platform users, 67.7% (152,464) responded to the recommendation question at J0, 15% (33,823) reported health improvements at J30, and 10% (22,596) discovered sustainable health strategies. Most users were women (68.6%). Key motivations included well-being and personal development (17.4%), stress, anxiety, and phobias (17.1%), and sleep disorders (7%). Hypnosis (15%), traditional Chinese medicine (8.4%), and reflexology (6.7%) were the most commonly selected modalities. At J30, 74.8% reported health improvements, with notable benefits for well-being (80.7%) and stress (76.3%). <b><i>Conclusion:</i></b> This study underscores the growing demand for CIM therapies in France, driven by a need for stress relief, personal development, and physical and psychological health management. High satisfaction rates and perceived health benefits highlight the potential of CIM to complement conventional care. Integrating evidence-based CIM into mainstream health care systems, as recommended by the WHO, offers an opportunity to address patient needs and enhance health care delivery.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vibha Malhotra, Joanna E Harnett, Keith Wong, Bandana Saini
Objective: Naturopathic practitioners consult an estimated 6.2% of Australian adults, equating to 1,550,000 people receiving their care each year. Sleep is now recognized as a key pillar of health; however, nearly half of all Australian adults report inadequate sleep. Evidence suggests that many Australians consult naturopaths (NPs) for sleep-related problems and use complementary medicines (CMs) to manage these. However, NPs' clinical approach to caring for people living with sleep disorders has not been reported. Therefore, the aim of this study was to describe and understand the clinical assessment and treatment approaches used by NPs in their care of people living with sleep disorders. Materials and Methods: A cross-sectional online survey with a purposively sought sample. NPs were recruited via the practitioner research-based network. The participants received an email invitation containing a link to the survey along with a Participant Information Sheet. The online survey (Research Electronic Data Capture-see Supplementary Data S1) comprised multiple-choice, binary (yes/no) questions, or 5-point Likert scale-type questions structured across four sections related to: clinical assessment of patients, treatments used, interprofessional communication with conventional doctors, and demographics. Results: Sixty-seven complete data sets were analyzed. Most survey participants treated-one to three patients with sleep disorders weekly, being consulted primarily for insomnia (82%) and its treatment (98.5%). Comprehensive sleep health histories were commonly assessed. Additionally, 69% of participants reported that patients sought their services to complement conventional care. The most frequently used complementary medicine (CM) approaches included sleep hygiene counseling (75%) and meditation (64.7%). Vitamins, minerals, herbal medicines, and nutritional supplements were the most recommended CM medicines (92.6%). Referrals to conventional medicine professionals were minimal. Conclusion: Australian NPs are frequently consulted by people living with sleep disorders who are also using conventional medicines. Our study highlights the need for integrated models of health care tailored to patient needs that maximize potential benefits and reduce any harms associated with drug-CMs interactions. The provision of training to the Australian health care workforce of NPs that focuses on evidence-based behavioral treatments can improve access to these treatments for patients.
{"title":"Australian Naturopaths Approach to the Clinical Management of Patients Presenting with Sleep Disorders.","authors":"Vibha Malhotra, Joanna E Harnett, Keith Wong, Bandana Saini","doi":"10.1089/jicm.2024.0422","DOIUrl":"https://doi.org/10.1089/jicm.2024.0422","url":null,"abstract":"<p><p><b><i>Objective:</i></b> Naturopathic practitioners consult an estimated 6.2% of Australian adults, equating to 1,550,000 people receiving their care each year. Sleep is now recognized as a key pillar of health; however, nearly half of all Australian adults report inadequate sleep. Evidence suggests that many Australians consult naturopaths (NPs) for sleep-related problems and use complementary medicines (CMs) to manage these. However, NPs' clinical approach to caring for people living with sleep disorders has not been reported. Therefore, the aim of this study was to describe and understand the clinical assessment and treatment approaches used by NPs in their care of people living with sleep disorders. <b><i>Materials and Methods:</i></b> A cross-sectional online survey with a purposively sought sample. NPs were recruited via the practitioner research-based network. The participants received an email invitation containing a link to the survey along with a Participant Information Sheet. The online survey (Research Electronic Data Capture-see Supplementary Data S1) comprised multiple-choice, binary (yes/no) questions, or 5-point Likert scale-type questions structured across four sections related to: clinical assessment of patients, treatments used, interprofessional communication with conventional doctors, and demographics. <b><i>Results:</i></b> Sixty-seven complete data sets were analyzed. Most survey participants treated-one to three patients with sleep disorders weekly, being consulted primarily for insomnia (82%) and its treatment (98.5%). Comprehensive sleep health histories were commonly assessed. Additionally, 69% of participants reported that patients sought their services to complement conventional care. The most frequently used complementary medicine (CM) approaches included sleep hygiene counseling (75%) and meditation (64.7%). Vitamins, minerals, herbal medicines, and nutritional supplements were the most recommended CM medicines (92.6%). Referrals to conventional medicine professionals were minimal. <b><i>Conclusion:</i></b> Australian NPs are frequently consulted by people living with sleep disorders who are also using conventional medicines. Our study highlights the need for integrated models of health care tailored to patient needs that maximize potential benefits and reduce any harms associated with drug-CMs interactions. The provision of training to the Australian health care workforce of NPs that focuses on evidence-based behavioral treatments can improve access to these treatments for patients.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-09-25DOI: 10.1089/jicm.2024.0301
Katherine C Britt, Augustine C O Boateng, Benjamin R Doolittle
{"title":"Advancing the Effectiveness of Holistic Care in the United States: Integrating Religion and Spirituality.","authors":"Katherine C Britt, Augustine C O Boateng, Benjamin R Doolittle","doi":"10.1089/jicm.2024.0301","DOIUrl":"10.1089/jicm.2024.0301","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"100-104"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-01-06DOI: 10.1089/jicm.2024.0994
L Susan Wieland
{"title":"Synopses of Cochrane Reviews from Cochrane Library Issue 6 2024 Through Issue 9 2024.","authors":"L Susan Wieland","doi":"10.1089/jicm.2024.0994","DOIUrl":"10.1089/jicm.2024.0994","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"8-10"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-10-14DOI: 10.1089/jicm.2023.0124
Li Li, Yuanyuan Wang, Shanglong Wang, Jiancheng Zong, Zengliang Zhang, Shengcan Zou, Zhen Zhao, Yu Cao, Zimin Liu
Background: Current treatments for osteoarthritis (OA) pain and stiffness have limitations, including adverse effects. Therefore, effective and safe complementary or alternative therapies are needed. Dietary supplement GJ 191, comprising Epimedium, Dioscorea, and Salvia miltiorrhiza extracts, may address this need. Methods: This randomized, double-blind, placebo-controlled study investigated GJ 191 supplementation on knee OA symptoms. Seventy-two adults (40-75 years) with mild to moderate knee OA and mild to moderate knee pain were enrolled. The Knee Injury and Osteoarthritis Outcome Score (KOOS), Pain Visual Analog Scale (VAS), Quality of Life questionnaire, knee joint range of motion, serum C-reactive protein, and rescue medication use were assessed. The Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) pain and stiffness scores were computed using KOOS scores. Results: Decreases in WOMAC pain scores were reported by both GJ 191 and placebo groups after 6 (-1.78 ± 2.71 and -1.34 ± 1.93, respectively; p < 0.01) and 12 (-2.31 ± 2.83 and -1.59 ± 2.69, respectively; p < 0.01) weeks, with no significant difference between groups. There were decreases in WOMAC stiffness scores for participants supplemented with GJ 191 by 0.53 ± 1.22 and 0.72 ± 1.46 (p ≤0.02) after 6 and 12 weeks, respectively, with respective decreases of 0.81 ± 1.51 and 0.75 ± 1.85 (p ≤0.03) for those on placebo. Significant improvements in current pain, as assessed by the Pain VAS, and bodily pain were reported by the GJ 191 group after 6 and 12 weeks, while the placebo group only reported significant improvements in these measures after 12 weeks. GJ 191 supplementation was safe and well tolerated. Conclusion: There was no significant difference in pain and stiffness scores between GJ 191 and placebo over the 12 weeks. While both groups reported improvements in WOMAC pain from baseline, improvements in current and bodily pain were experienced sooner with GJ 191 than placebo and were sustained over the study period. GJ 191 supplementation was safe and well tolerated. (CTR#: NCT04395547).
{"title":"A Randomized, Double-Blind, Placebo-Controlled Study Investigating the Safety and Efficacy of a Herbal Formulation on Knee Joint Function in Adults with Knee Osteoarthritis.","authors":"Li Li, Yuanyuan Wang, Shanglong Wang, Jiancheng Zong, Zengliang Zhang, Shengcan Zou, Zhen Zhao, Yu Cao, Zimin Liu","doi":"10.1089/jicm.2023.0124","DOIUrl":"10.1089/jicm.2023.0124","url":null,"abstract":"<p><p><b><i>Background:</i></b> Current treatments for osteoarthritis (OA) pain and stiffness have limitations, including adverse effects. Therefore, effective and safe complementary or alternative therapies are needed. Dietary supplement GJ 191, comprising <i>Epimedium, Dioscorea, and Salvia miltiorrhiza</i> extracts, may address this need. <b><i>Methods:</i></b> This randomized, double-blind, placebo-controlled study investigated GJ 191 supplementation on knee OA symptoms. Seventy-two adults (40-75 years) with mild to moderate knee OA and mild to moderate knee pain were enrolled. The Knee Injury and Osteoarthritis Outcome Score (KOOS), Pain Visual Analog Scale (VAS), Quality of Life questionnaire, knee joint range of motion, serum C-reactive protein, and rescue medication use were assessed. The Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) pain and stiffness scores were computed using KOOS scores. <b><i>Results:</i></b> Decreases in WOMAC pain scores were reported by both GJ 191 and placebo groups after 6 (-1.78 ± 2.71 and -1.34 ± 1.93, respectively; <i>p</i> < 0.01) and 12 (-2.31 ± 2.83 and -1.59 ± 2.69, respectively; <i>p</i> < 0.01) weeks, with no significant difference between groups. There were decreases in WOMAC stiffness scores for participants supplemented with GJ 191 by 0.53 ± 1.22 and 0.72 ± 1.46 (<i>p</i> ≤0.02) after 6 and 12 weeks, respectively, with respective decreases of 0.81 ± 1.51 and 0.75 ± 1.85 (<i>p</i> ≤0.03) for those on placebo. Significant improvements in current pain, as assessed by the Pain VAS, and bodily pain were reported by the GJ 191 group after 6 and 12 weeks, while the placebo group only reported significant improvements in these measures after 12 weeks. GJ 191 supplementation was safe and well tolerated. <b><i>Conclusion:</i></b> There was no significant difference in pain and stiffness scores between GJ 191 and placebo over the 12 weeks. While both groups reported improvements in WOMAC pain from baseline, improvements in current and bodily pain were experienced sooner with GJ 191 than placebo and were sustained over the study period. GJ 191 supplementation was safe and well tolerated. (CTR#: NCT04395547).</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"54-63"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-08-02DOI: 10.1089/jicm.2023.0741
Mengqin Zhang, Xing Liu, Yan Huang
Objectives: To systematically synthesize the current evidence on the effects of art-based interventions on improving anxiety, depression, stress, sleep, and well-being of cancer caregivers. Design: A systematic review. Methods: We searched PubMed, EMBASE, Web of Science, CINAHL, PsycINFO, and Cochrane Central Register of Controlled Trials databases from their inception up to April 2024. Studies exploring the effects of art-based interventions on the psychological symptoms of cancer caregivers were included. We did not restrict the publication to the particular study designs, including randomized controlled trials, quasiexperimental studies, and qualitative studies. Results: Fifteen studies of 607 participants were identified in this systematic review. Overall, the existing studies provided preliminary evidence to suggest that art-based interventions may benefit cancer caregivers in improving anxiety, depression, stress, caregiver burden, and quality of life. However, the relatively low quality of the current evidence limits the efficacy of these findings. Conclusions: According to the existing evidence, the therapeutic benefits of using art-based interventions for improving the psychological well-being of cancer caregivers are uncertain. More high-quality and well-designed studies are still required to confirm the psychological effectiveness of art-based interventions for cancer caregivers in the future.
目的系统地综合目前以艺术为基础的干预措施对改善癌症护理人员的焦虑、抑郁、压力、睡眠和幸福感的效果的证据。设计:系统综述。方法:检索我们检索了 PubMed、EMBASE、Web of Science、CINAHL、PsycINFO 和 Cochrane Central Register of Controlled Trials 数据库从开始到 2024 年 4 月的所有内容。我们纳入了探讨艺术干预对癌症护理者心理症状影响的研究。我们并没有限制发表的研究设计,包括随机对照试验、准实验研究和定性研究。研究结果本系统综述共确定了 15 项研究,参与人数达 607 人。总体而言,现有的研究提供了初步证据,表明基于艺术的干预措施可能有利于癌症护理者改善焦虑、抑郁、压力、护理者负担和生活质量。然而,目前证据的质量相对较低,限制了这些研究结果的有效性。结论:根据现有证据,使用艺术干预改善癌症护理者心理健康的治疗效果尚不确定。未来仍需要更多高质量和设计良好的研究来证实艺术干预对癌症护理者的心理疗效。
{"title":"Are Art-Based Interventions Effective in Improving Psychological Well-Being Among Informal Caregivers of Cancer Patients? A Systematic Review.","authors":"Mengqin Zhang, Xing Liu, Yan Huang","doi":"10.1089/jicm.2023.0741","DOIUrl":"10.1089/jicm.2023.0741","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> To systematically synthesize the current evidence on the effects of art-based interventions on improving anxiety, depression, stress, sleep, and well-being of cancer caregivers. <b><i>Design:</i></b> A systematic review. <b><i>Methods:</i></b> We searched PubMed, EMBASE, Web of Science, CINAHL, PsycINFO, and Cochrane Central Register of Controlled Trials databases from their inception up to April 2024. Studies exploring the effects of art-based interventions on the psychological symptoms of cancer caregivers were included. We did not restrict the publication to the particular study designs, including randomized controlled trials, quasiexperimental studies, and qualitative studies. <b><i>Results:</i></b> Fifteen studies of 607 participants were identified in this systematic review. Overall, the existing studies provided preliminary evidence to suggest that art-based interventions may benefit cancer caregivers in improving anxiety, depression, stress, caregiver burden, and quality of life. However, the relatively low quality of the current evidence limits the efficacy of these findings. <b><i>Conclusions:</i></b> According to the existing evidence, the therapeutic benefits of using art-based interventions for improving the psychological well-being of cancer caregivers are uncertain. More high-quality and well-designed studies are still required to confirm the psychological effectiveness of art-based interventions for cancer caregivers in the future.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"11-24"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-11-26DOI: 10.1089/jicm.2024.0942
Darshan H Mehta
{"title":"Beyond the Pause: Mind-Body Pathways to Menopausal Health.","authors":"Darshan H Mehta","doi":"10.1089/jicm.2024.0942","DOIUrl":"10.1089/jicm.2024.0942","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"4-7"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Evidence suggests that post-coronavirus disease 2019 (COVID-19) is associated with reduced health-related quality of life, and up to 80% of those infected with COVID-19 may experience these symptoms. The objective of the present study was to identify the effects of individualized homeopathic medicinal products (IHMPs) against placebos in postCOVID-19 conditions. Design: Double-blind, randomized (1:1), two parallel arms, placebo-controlled, feasibility trial. Setting: D. N. De Homoeopathic Medical College & Hospital, Kolkata, West Bengal, India. Subjects: Sixty participants with post-COVID-19 conditions. Interventions: Group verum (n = 30; IHMPs plus concomitant care) versus group control (n = 30; placebos plus concomitant care). Outcome Measures: Feasibility issues; primary-post-COVID-19 symptoms checklist; secondary-Measure Yourself Medical Outcomes Profile version 2 (MYMOP-2); all of them were measured at baseline, and monthly intervals, up to 3 months. The intention-to-treat sample was analyzed; group differences were reported using descriptive statistics: means, 95% confidence intervals (CIs), and between group effect sizes (Cohen's d). Results: Feasibility concerns showed promise; recruitment, retention, and attrition rates were 34.2%, 95%, and 5%, respectively. Group differences in both primary and secondary outcomes favored IHMPs against placebos: symptoms checklist score mean difference after 3 months: -4.2, 95% CI -4.9 to -3.4, d = 2.854 and MYMOP-2 mean difference after 3 months: -2.2, 95% CI -2.8 to -1.7, d = 2.082, respectively. Natrum muriaticum (11.7%), Pulsatilla nigricans (10%), Rhus toxicodendron (8.3%), and Calcarea carbonica (8.3%) were the most frequently prescribed remedies. Conclusions: IHMPs produced better results than placebos in reducing symptoms checklist scores and MYMOP-2 scores in the treatment of post-COVID-19 conditions. Definitive trials are warranted to confirm the findings.
目的:有证据表明,2019年后冠状病毒病(COVID-19)与健康相关的生活质量下降有关,多达80%的COVID-19感染者可能会出现这些症状。本研究旨在确定个体化顺势疗法药物产品(IHMPs)与安慰剂在COVID-19后症状中的对比效果。设计:双盲、随机(1:1)、两组平行、安慰剂对照、可行性试验。试验地点印度西孟加拉邦加尔各答 D. N. De 顺势疗法医学院和医院。受试者:60名患有COVID-19后遗症的参与者。干预措施:verum组(n = 30;IHMPs加辅助护理)与对照组(n = 30;安慰剂加辅助护理)。结果测量:可行性问题;主要--COVID-19 后症状检查表;次要--Measure Yourself Medical Outcomes Profile version 2 (MYMOP-2);所有测量均在基线和每月间隔期进行,直至 3 个月。对意向治疗样本进行了分析;采用描述性统计方法报告了组间差异:平均值、95% 置信区间(CI)和组间效应大小(Cohen's d)。结果可行性研究结果表明,招募率、保留率和流失率分别为 34.2%、95% 和 5%。与安慰剂相比,IHMPs 在主要结果和次要结果上的组间差异更有利:3 个月后症状检查表得分的平均差异为-4.2,95% C:3个月后症状核对表得分平均差异:-4.2,95% CI -4.9至-3.4,d = 2.854;3个月后MYMOP-2平均差异:-2.2,95% CI -4.9至-3.4,d = 2.854:分别为-2.2,95% CI -2.8至-1.7,d = 2.082。最常使用的处方药是鼠曲草(11.7%)、白头翁(10%)、毒玫瑰(8.3%)和石菖蒲(8.3%)。结论在治疗 COVID-19 后遗症时,IHMP 在降低症状检查表评分和 MYMOP-2 评分方面的效果优于安慰剂。有必要进行最终试验来证实这些发现。
{"title":"Individualized Homeopathic Medicinal Products in the Treatment of Post-COVID-19 Conditions: A Double-Blind, Randomized, Placebo-Controlled, Feasibility Trial.","authors":"Abhijit Rana, Pulakendu Bhattacharya, Subhasish Ganguly, Sangita Saha, Satyajit Naskar, Shubhamoy Ghosh, Abdur Rahaman Shaikh, Munmun Koley, Subhranil Saha, Shyamal Kumar Mukherjee","doi":"10.1089/jicm.2024.0102","DOIUrl":"10.1089/jicm.2024.0102","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> Evidence suggests that post-coronavirus disease 2019 (COVID-19) is associated with reduced health-related quality of life, and up to 80% of those infected with COVID-19 may experience these symptoms. The objective of the present study was to identify the effects of individualized homeopathic medicinal products (IHMPs) against placebos in postCOVID-19 conditions. <b><i>Design:</i></b> Double-blind, randomized (1:1), two parallel arms, placebo-controlled, feasibility trial. <b><i>Setting:</i></b> D. N. De Homoeopathic Medical College & Hospital, Kolkata, West Bengal, India. <b><i>Subjects:</i></b> Sixty participants with post-COVID-19 conditions. <b><i>Interventions:</i></b> Group verum (<i>n</i> = 30; IHMPs plus concomitant care) versus group control (<i>n</i> = 30; placebos plus concomitant care). <b><i>Outcome Measures:</i></b> Feasibility issues; primary-post-COVID-19 symptoms checklist; secondary-Measure Yourself Medical Outcomes Profile version 2 (MYMOP-2); all of them were measured at baseline, and monthly intervals, up to 3 months. The intention-to-treat sample was analyzed; group differences were reported using descriptive statistics: means, 95% confidence intervals (CIs), and between group effect sizes (Cohen's <i>d</i>). <b><i>Results:</i></b> Feasibility concerns showed promise; recruitment, retention, and attrition rates were 34.2%, 95%, and 5%, respectively. Group differences in both primary and secondary outcomes favored IHMPs against placebos: symptoms checklist score mean difference after 3 months: -4.2, 95% CI -4.9 to -3.4, <i>d</i> = 2.854 and MYMOP-2 mean difference after 3 months: -2.2, 95% CI -2.8 to -1.7, <i>d</i> = 2.082, respectively. <i>Natrum muriaticum</i> (11.7%), <i>Pulsatilla nigricans</i> (10%), <i>Rhus toxicodendron</i> (8.3%), and <i>Calcarea carbonica</i> (8.3%) were the most frequently prescribed remedies. <b><i>Conclusions:</i></b> IHMPs produced better results than placebos in reducing symptoms checklist scores and MYMOP-2 scores in the treatment of post-COVID-19 conditions. Definitive trials are warranted to confirm the findings.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"64-74"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1089/jicm.2024.31127.revack
{"title":"Acknowledgment of Reviewers 2024.","authors":"","doi":"10.1089/jicm.2024.31127.revack","DOIUrl":"https://doi.org/10.1089/jicm.2024.31127.revack","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":"31 1","pages":"105-107"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2024-12-23DOI: 10.1089/jicm.2024.1001
Holger Cramer
{"title":"Research in Integrative and Complementary Medicine: Particularities, Challenges, Obstacles, and Misunderstandings. Part 1: The Why and the How of Clinical Research.","authors":"Holger Cramer","doi":"10.1089/jicm.2024.1001","DOIUrl":"10.1089/jicm.2024.1001","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1-3"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}