Pub Date : 2025-11-03DOI: 10.1177/27683605251392014
{"title":"Abstract Author Index <i>by abstract number</i>.","authors":"","doi":"10.1177/27683605251392014","DOIUrl":"https://doi.org/10.1177/27683605251392014","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-03DOI: 10.1177/27683605251386132
{"title":"Abstracts from Society for Acupuncture Research Cultivating Interconnections of Acupuncture and Traditional East Asian Medicine Research Newport Beach, CA, USA <i>April 3-6, 2025</i>.","authors":"","doi":"10.1177/27683605251386132","DOIUrl":"https://doi.org/10.1177/27683605251386132","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Knee arthroplasty or knee joint replacement is a common treatment method used to relieve pain caused by knee arthritis among the elderly. Postoperative pain control is a challenge in knee arthroplasty. Despite existing evidence supporting the effectiveness of acupressure for pain management, limited research has directly compared the efficacy of body and auricular acupressure in reducing pain following knee arthroplasty. To address this knowledge gap, the present study aims to compare the effectiveness of these two acupressure techniques in alleviating pain severity among elderly individuals undergoing knee replacement surgery. Methods: This three-group randomized clinical trial study was conducted on 141 elderly women undergoing knee arthroplasty surgery at Shafa Yahiaeian Hospital in Tehran in 2023. Patients were randomly assigned to three groups of 47. The patients of the body acupressure and auricular acupressure groups received intervention for 15 min, thrice a day at an interval of 4 h, for 3 days. Control group patients received only routine interventions. Visual analog scale (VAS) and McGill's Abbreviated Mental Test Scale were completed before the first intervention on the first day and immediately after the last intervention on the first, second, and third days. Results: The results revealed that the pain severity assessed using VAS and McGill's Abbreviated Mental Test Scale during all 3 days in the body and auricular acupressure groups had a more decreasing trend compared with the control group. Moreover, auricular acupressure was more effective than body acupressure in pain control. Conclusion: Body acupressure and auricular acupressure as complementary interventions have significant potential in reducing pain after knee arthroplasty in the elderly female population. These methods offer an interesting treatment option by reducing the need for analgesics and thus reducing the side effects of these drugs. However, auricular acupressure may have faster relief effects compared with body acupressure.
{"title":"Comparative Effectiveness of Ear and Body Acupressure for Postoperative Pain in Elderly Women Following Knee Arthroplasty: A Randomized Trial.","authors":"Fatemeh Ghanbari, Nahid Rejeh, Tahereh Bahrami, Hooman Yahyazadeh, Kiarash Saatchi","doi":"10.1177/27683605251377400","DOIUrl":"10.1177/27683605251377400","url":null,"abstract":"<p><p><b><i>Background:</i></b> Knee arthroplasty or knee joint replacement is a common treatment method used to relieve pain caused by knee arthritis among the elderly. Postoperative pain control is a challenge in knee arthroplasty. Despite existing evidence supporting the effectiveness of acupressure for pain management, limited research has directly compared the efficacy of body and auricular acupressure in reducing pain following knee arthroplasty. To address this knowledge gap, the present study aims to compare the effectiveness of these two acupressure techniques in alleviating pain severity among elderly individuals undergoing knee replacement surgery. <b><i>Methods:</i></b> This three-group randomized clinical trial study was conducted on 141 elderly women undergoing knee arthroplasty surgery at Shafa Yahiaeian Hospital in Tehran in 2023. Patients were randomly assigned to three groups of 47. The patients of the body acupressure and auricular acupressure groups received intervention for 15 min, thrice a day at an interval of 4 h, for 3 days. Control group patients received only routine interventions. Visual analog scale (VAS) and McGill's Abbreviated Mental Test Scale were completed before the first intervention on the first day and immediately after the last intervention on the first, second, and third days. <b><i>Results:</i></b> The results revealed that the pain severity assessed using VAS and McGill's Abbreviated Mental Test Scale during all 3 days in the body and auricular acupressure groups had a more decreasing trend compared with the control group. Moreover, auricular acupressure was more effective than body acupressure in pain control. <b><i>Conclusion:</i></b> Body acupressure and auricular acupressure as complementary interventions have significant potential in reducing pain after knee arthroplasty in the elderly female population. These methods offer an interesting treatment option by reducing the need for analgesics and thus reducing the side effects of these drugs. However, auricular acupressure may have faster relief effects compared with body acupressure.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"987-996"},"PeriodicalIF":1.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-07-15DOI: 10.1177/27683605251360928
Davy Vancampfort, James Mugisha
{"title":"Expanding the Role of Physiotherapists in Delivering Body-Mind Interventions for Mental Health in Low-Income Countries.","authors":"Davy Vancampfort, James Mugisha","doi":"10.1177/27683605251360928","DOIUrl":"10.1177/27683605251360928","url":null,"abstract":"","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"1005-1006"},"PeriodicalIF":1.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-06-17DOI: 10.1089/jicm.2025.0131
Melanie Anheyer, Holger Cramer, Thomas Ostermann, Alfred Längler, Dennis Anheyer
<p><p><b><i>Introduction:</i></b> Herpes labialis, commonly caused by herpes simplex virus type 1, affects millions globally and is traditionally managed with nucleoside antiviral drugs. However, increasing interest in complementary and integrative therapies has led to the exploration of topical herbal treatments as potential alternatives or adjuncts in managing this condition. <b><i>Methods:</i></b> A systematic review was conducted in accordance with Cochrane guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations, with prior registration. A comprehensive search of Medline/PubMed, Scopus, and the Cochrane Central Register of Controlled Trials was performed from inception to June 17, 2024. After screening 7,386 nonduplicate records and assessing 346 full-text articles, 7 randomized controlled trials (RCTs) encompassing 1,250 patients were included. Data were extracted regarding intervention types, outcomes, and adverse events, and the risk of bias was evaluated using the Cochrane Risk of Bias Tool. <b><i>Results:</i></b> The included studies evaluated topical formulations of lemon balm (<i>Melissa officinalis</i> L.), olive leaf extract (<i>Olea europaea</i> L.), propolis, and a combined sage-rhubarb cream (<i>Salvia officinalis</i> L., <i>Rheum palmatum</i> L., and <i>Rheum officinale</i> Baill.). Lemon balm preparations consistently reduced pain intensity and swelling, with some studies also reporting a significant decrease in lesion size compared with placebo or acyclovir. Olive leaf extract demonstrated a statistically significant faster improvement in symptoms and a shorter healing time compared with acyclovir. Compared with acyclovir, propolis formulations significantly shortened the median time to lesion encrustation and complete healing compared with acyclovir, and the combined sage-rhubarb cream showed a comparable efficacy to acyclovir in mean healing time. Overall, the risk of bias was judged to be low in two trials, while five trials raised some concerns. The total sample size across studies was small, potentially limiting the generalizability of the results. Across all studies, adverse events were minimal or absent. <b><i>Discussion:</i></b> The findings indicate that topical herbal therapies may provide effective and well-tolerated alternatives or adjuncts to conventional antiviral treatments for herpes labialis. However, considerable heterogeneity in intervention protocols and outcome measures, as well as the underrepresentation of pediatric populations, limit the generalizability of these findings. <b><i>Conclusion</i>:</b> Topical herbal interventions, including lemon balm, olive leaf extract, propolis, and sage-rhubarb formulations, demonstrate potential benefits in managing herpes labialis with favorable safety profiles. Future well-designed, large-scale RCTs employing standardized methodologies are necessary to confirm these findings and to establish optimal treatment protocols for di
{"title":"Herbal Medicine for Treating Herpes Labialis: A Systematic Review.","authors":"Melanie Anheyer, Holger Cramer, Thomas Ostermann, Alfred Längler, Dennis Anheyer","doi":"10.1089/jicm.2025.0131","DOIUrl":"10.1089/jicm.2025.0131","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Herpes labialis, commonly caused by herpes simplex virus type 1, affects millions globally and is traditionally managed with nucleoside antiviral drugs. However, increasing interest in complementary and integrative therapies has led to the exploration of topical herbal treatments as potential alternatives or adjuncts in managing this condition. <b><i>Methods:</i></b> A systematic review was conducted in accordance with Cochrane guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations, with prior registration. A comprehensive search of Medline/PubMed, Scopus, and the Cochrane Central Register of Controlled Trials was performed from inception to June 17, 2024. After screening 7,386 nonduplicate records and assessing 346 full-text articles, 7 randomized controlled trials (RCTs) encompassing 1,250 patients were included. Data were extracted regarding intervention types, outcomes, and adverse events, and the risk of bias was evaluated using the Cochrane Risk of Bias Tool. <b><i>Results:</i></b> The included studies evaluated topical formulations of lemon balm (<i>Melissa officinalis</i> L.), olive leaf extract (<i>Olea europaea</i> L.), propolis, and a combined sage-rhubarb cream (<i>Salvia officinalis</i> L., <i>Rheum palmatum</i> L., and <i>Rheum officinale</i> Baill.). Lemon balm preparations consistently reduced pain intensity and swelling, with some studies also reporting a significant decrease in lesion size compared with placebo or acyclovir. Olive leaf extract demonstrated a statistically significant faster improvement in symptoms and a shorter healing time compared with acyclovir. Compared with acyclovir, propolis formulations significantly shortened the median time to lesion encrustation and complete healing compared with acyclovir, and the combined sage-rhubarb cream showed a comparable efficacy to acyclovir in mean healing time. Overall, the risk of bias was judged to be low in two trials, while five trials raised some concerns. The total sample size across studies was small, potentially limiting the generalizability of the results. Across all studies, adverse events were minimal or absent. <b><i>Discussion:</i></b> The findings indicate that topical herbal therapies may provide effective and well-tolerated alternatives or adjuncts to conventional antiviral treatments for herpes labialis. However, considerable heterogeneity in intervention protocols and outcome measures, as well as the underrepresentation of pediatric populations, limit the generalizability of these findings. <b><i>Conclusion</i>:</b> Topical herbal interventions, including lemon balm, olive leaf extract, propolis, and sage-rhubarb formulations, demonstrate potential benefits in managing herpes labialis with favorable safety profiles. Future well-designed, large-scale RCTs employing standardized methodologies are necessary to confirm these findings and to establish optimal treatment protocols for di","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"946-954"},"PeriodicalIF":1.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-08-20DOI: 10.1177/27683605251370146
Alex Sargsyan, Lora H Beebe, Frances Horn, Sandra Thomas
Background: Green Care therapies were developed in the late 20th century as nature-based interventions aimed at supporting recovery for individuals with mental and physical health challenges. Animal-assisted therapy with farm animals (AATF), a branch of Green Care, involves engaging individuals with farm animals in natural settings to promote healing. Previous studies have shown the benefits of animal-assisted therapies (AAT) for individuals with traumatic brain injury (TBI), suggesting AATF could offer similar advantages. This study aimed to examine the impact of an AATF program using domesticated ducks as therapeutic companions for individuals with TBI. Objective: The primary objective was to explore how individuals with TBI perceive their participation in an AATF-based therapeutic intervention. Methods: The study involved a 12-week AATF program, with semi-structured interviews conducted postintervention to capture participants' experiences. A qualitative descriptive approach with atheoretical thematic analysis was employed to identify key themes from the data. Results: Four key themes were developed from the analysis: Emotional Wellbeing, Attachment, Care, and Nature and Environment. These themes reflected participants' shared experiences and highlighted the perceived benefits of AATF in TBI rehabilitation. Conclusion: This study presents AATF, specifically involving domesticated ducks, as an innovative therapeutic intervention for individuals with TBI. The findings suggest that fostering meaningful connections with animals significantly enhances emotional well-being and provides a promising approach to improving rehabilitation outcomes for individuals living with TBI.
{"title":"Exploring the Perceptions of Individuals with Traumatic Brain Injury Participating in Animal-Assisted Therapy with Domesticated Ducks.","authors":"Alex Sargsyan, Lora H Beebe, Frances Horn, Sandra Thomas","doi":"10.1177/27683605251370146","DOIUrl":"10.1177/27683605251370146","url":null,"abstract":"<p><p><b><i>Background:</i></b> Green Care therapies were developed in the late 20th century as nature-based interventions aimed at supporting recovery for individuals with mental and physical health challenges. Animal-assisted therapy with farm animals (AATF), a branch of Green Care, involves engaging individuals with farm animals in natural settings to promote healing. Previous studies have shown the benefits of animal-assisted therapies (AAT) for individuals with traumatic brain injury (TBI), suggesting AATF could offer similar advantages. This study aimed to examine the impact of an AATF program using domesticated ducks as therapeutic companions for individuals with TBI. <b><i>Objective:</i></b> The primary objective was to explore how individuals with TBI perceive their participation in an AATF-based therapeutic intervention. <b><i>Methods:</i></b> The study involved a 12-week AATF program, with semi-structured interviews conducted postintervention to capture participants' experiences. A qualitative descriptive approach with atheoretical thematic analysis was employed to identify key themes from the data. <b><i>Results:</i></b> Four key themes were developed from the analysis: Emotional Wellbeing, Attachment, Care, and Nature and Environment. These themes reflected participants' shared experiences and highlighted the perceived benefits of AATF in TBI rehabilitation. <b><i>Conclusion:</i></b> This study presents AATF, specifically involving domesticated ducks, as an innovative therapeutic intervention for individuals with TBI. The findings suggest that fostering meaningful connections with animals significantly enhances emotional well-being and provides a promising approach to improving rehabilitation outcomes for individuals living with TBI.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"997-1004"},"PeriodicalIF":1.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-07-18DOI: 10.1177/27683605251360930
Zhanette Coffee, Terry A Badger, Ruth Taylor-Piliae, Todd W Vanderah, Chong Ho Yu, Judith S Gordon
Background: Opioid use disorder (OUD) remains a global crisis, with chronic pain (CP), anxiety, and opioid cravings contributing to treatment discontinuation and return to opioid use. Despite the effectiveness of medications for OUD (MOUD) such as buprenorphine and methadone, they are underutilized, with nearly 50% of individuals discontinuing prematurely or returning to opioid use. Mind-body therapies (e.g., mindfulness, acupuncture, Tai Chi) have shown promise in reducing stress, drug cravings, and pain while improving well-being. However, Tai Chi has not been systematically tested for individuals with OUD and co-occurring CP and anxiety. The authors aimed to evaluate the feasibility of a virtual Tai Chi Easy (vTCE) intervention as an adjunct therapy for adults with OUD and co-occurring CP, and/or anxiety. Methods: A theory-driven, pre-post, single-group quasi-experimental design was used to evaluate intervention feasibility benchmarks and conduct baseline comparisons between inpatient and outpatient participants. The 8-week vTCE intervention consisted of gentle movements, breathing exercises, self-massage, and mindfulness practices, integrating these components into a holistic mind-body approach. Results: Of 32 screened individuals, 19 enrolled and 15 participated. Recruitment goals were partially met after expanding to outpatient settings (65% of the target). Retention was low, with only 3 participants (15.8%) completing the final assessment. Presurvey completion was high (95%), but postsurvey completion was limited (15.7%). Adherence was low, with only 20% attending more than one session. Acceptability and appropriateness averaged 3.5/5, and feasibility reached 4/5. No injuries were reported, supporting intervention safety. Conclusion: The vTCE intervention was not feasible in the inpatient setting. Outpatient settings showed greater feasibility, with notable differences in baseline characteristics, including self-reported opioid cravings. Lessons learned from this pilot study highlight the need to tailor recruitment, retention, and intervention strategies for future research testing vTCE as an adjunct therapy for individuals with OUD and co-occurring symptoms receiving outpatient MOUD. Trial Registration: ClinicalTrials.gov (Identifier: NCT05850533). Registered: 04/25/2023.
{"title":"Tai Chi Easy for Opioid Use Disorder: Pilot Feasibility Outcomes and Lessons Learned.","authors":"Zhanette Coffee, Terry A Badger, Ruth Taylor-Piliae, Todd W Vanderah, Chong Ho Yu, Judith S Gordon","doi":"10.1177/27683605251360930","DOIUrl":"10.1177/27683605251360930","url":null,"abstract":"<p><p><b><i>Background:</i></b> Opioid use disorder (OUD) remains a global crisis, with chronic pain (CP), anxiety, and opioid cravings contributing to treatment discontinuation and return to opioid use. Despite the effectiveness of medications for OUD (MOUD) such as buprenorphine and methadone, they are underutilized, with nearly 50% of individuals discontinuing prematurely or returning to opioid use. Mind-body therapies (e.g., mindfulness, acupuncture, Tai Chi) have shown promise in reducing stress, drug cravings, and pain while improving well-being. However, Tai Chi has not been systematically tested for individuals with OUD and co-occurring CP and anxiety. The authors aimed to evaluate the feasibility of a virtual Tai Chi Easy (vTCE) intervention as an adjunct therapy for adults with OUD and co-occurring CP, and/or anxiety. <b><i>Methods:</i></b> A theory-driven, pre-post, single-group quasi-experimental design was used to evaluate intervention feasibility benchmarks and conduct baseline comparisons between inpatient and outpatient participants. The 8-week vTCE intervention consisted of gentle movements, breathing exercises, self-massage, and mindfulness practices, integrating these components into a holistic mind-body approach. <b><i>Results:</i></b> Of 32 screened individuals, 19 enrolled and 15 participated. Recruitment goals were partially met after expanding to outpatient settings (65% of the target). Retention was low, with only 3 participants (15.8%) completing the final assessment. Presurvey completion was high (95%), but postsurvey completion was limited (15.7%). Adherence was low, with only 20% attending more than one session. Acceptability and appropriateness averaged 3.5/5, and feasibility reached 4/5. No injuries were reported, supporting intervention safety. <b><i>Conclusion:</i></b> The vTCE intervention was not feasible in the inpatient setting. Outpatient settings showed greater feasibility, with notable differences in baseline characteristics, including self-reported opioid cravings. Lessons learned from this pilot study highlight the need to tailor recruitment, retention, and intervention strategies for future research testing vTCE as an adjunct therapy for individuals with OUD and co-occurring symptoms receiving outpatient MOUD. <b><i>Trial Registration:</i></b> ClinicalTrials.gov (Identifier: NCT05850533). Registered: 04/25/2023.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"979-986"},"PeriodicalIF":1.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-06-11DOI: 10.1089/jicm.2024.1007
Christoph Dombrowsky, Sabine D Klein, Sandra Würtenberger, Stephan Baumgartner, Alexander L Tournier
Background: There is currently no generally accepted theory able to explain the observed clinical efficacy of homeopathy. The aim of this scoping review is to identify all theoretical approaches that have been used to explain homeopathy, with the objective of establishing a basis for identifying promising hypotheses and theories for future elaboration. Methods: Medline, Embase, Scopus, Web of Science, PhilPapers, several online library catalogs, and personal libraries were searched for original studies up to July 12, 2024. Screening and data extraction were performed independently by two reviewers. Publications were included if they developed or advanced theories or models related to homeopathy. The aspect of homeopathy addressed by each study was extracted: the Principle of Similars and/or Potentisation. The theories identified in this review could be grouped into 14 overarching theoretical frameworks. Results: In total, 2118 records were screened, 500 full texts were assessed for eligibility, and 216 studies were included in this review. Starting in 1832 until the late 20th century, only sporadic contributions were found. From the 1990s, a marked increase in scholarly output was recorded. Most first authors were established in Germany, the United States, the United Kingdom, or India. The frameworks with the highest number of contributions were humanities, complex systems, water structures, and weak quantum theory. Overall, 22% of included publications described theoretical approaches that tried to cover both main aspects of homeopathy, 46% only Potentisation, 20% only the Principle of Similars (and 11% were unspecific). The theories within the humanities framework focused more on the Principle of Similars, complex systems theories on both principles, and the theories within the water structures, nanostructures, and mathematical models frameworks focused mostly on the Potentisation aspect. Conclusions: This scoping review offers an overview of theories and models on the mode of action of homeopathy. These could be classified into 14 largely nonoverlapping frameworks. Unexpectedly, the placebo did not emerge as such a framework. In the next step, these theories would be assessed in terms of their quality, plausibility, compatibility with modern science, and experimental falsifiability.
背景:目前还没有公认的理论能够解释顺势疗法的临床疗效。本综述的目的是确定所有用于解释顺势疗法的理论方法,目的是为确定未来阐述的有希望的假设和理论奠定基础。方法:检索截至2024年7月12日的Medline、Embase、Scopus、Web of Science、PhilPapers、多个在线图书馆目录和个人图书馆的原始研究。筛选和数据提取由两名审稿人独立完成。如果出版物发展或改进了与顺势疗法相关的理论或模型,则纳入其中。每项研究所涉及的顺势疗法的方面被提取出来:相似和/或潜在原理。本综述中确定的理论可分为14个总体理论框架。结果:共有2118条记录被筛选,500篇全文被评估为合格,216项研究被纳入本综述。从1832年开始直到20世纪末,只有零星的贡献被发现。从20世纪90年代开始,学术产出显著增加。大多数第一作者都是在德国、美国、英国或印度创立的。贡献最多的框架是人文、复杂系统、水结构和弱量子理论。总的来说,22%的纳入的出版物描述了试图涵盖顺势疗法两个主要方面的理论方法,46%的出版物只有potentitisation, 20%的出版物只有相似原理(11%的出版物没有具体说明)。人文学科框架内的理论更多地侧重于相似原理、基于这两个原理的复杂系统理论,而水结构、纳米结构和数学模型框架内的理论主要侧重于潜能化方面。结论:本综述综述了顺势疗法作用模式的理论和模型。这些可以分为14个基本上互不重叠的框架。出乎意料的是,安慰剂并没有作为这样一个框架出现。下一步,这些理论将根据其质量、合理性、与现代科学的兼容性以及实验的可证伪性进行评估。
{"title":"Mapping the Theories and Models on the Mode of Action of Homeopathy: A Scoping Review.","authors":"Christoph Dombrowsky, Sabine D Klein, Sandra Würtenberger, Stephan Baumgartner, Alexander L Tournier","doi":"10.1089/jicm.2024.1007","DOIUrl":"10.1089/jicm.2024.1007","url":null,"abstract":"<p><p><b><i>Background:</i></b> There is currently no generally accepted theory able to explain the observed clinical efficacy of homeopathy. The aim of this scoping review is to identify all theoretical approaches that have been used to explain homeopathy, with the objective of establishing a basis for identifying promising hypotheses and theories for future elaboration. <b><i>Methods:</i></b> Medline, Embase, Scopus, Web of Science, PhilPapers, several online library catalogs, and personal libraries were searched for original studies up to July 12, 2024. Screening and data extraction were performed independently by two reviewers. Publications were included if they developed or advanced theories or models related to homeopathy. The aspect of homeopathy addressed by each study was extracted: the Principle of Similars and/or Potentisation. The theories identified in this review could be grouped into 14 overarching theoretical frameworks. <b><i>Results:</i></b> In total, 2118 records were screened, 500 full texts were assessed for eligibility, and 216 studies were included in this review. Starting in 1832 until the late 20th century, only sporadic contributions were found. From the 1990s, a marked increase in scholarly output was recorded. Most first authors were established in Germany, the United States, the United Kingdom, or India. The frameworks with the highest number of contributions were humanities, complex systems, water structures, and weak quantum theory. Overall, 22% of included publications described theoretical approaches that tried to cover both main aspects of homeopathy, 46% only Potentisation, 20% only the Principle of Similars (and 11% were unspecific). The theories within the humanities framework focused more on the Principle of Similars, complex systems theories on both principles, and the theories within the water structures, nanostructures, and mathematical models frameworks focused mostly on the Potentisation aspect. <b><i>Conclusions:</i></b> This scoping review offers an overview of theories and models on the mode of action of homeopathy. These could be classified into 14 largely nonoverlapping frameworks. Unexpectedly, the placebo did not emerge as such a framework. In the next step, these theories would be assessed in terms of their quality, plausibility, compatibility with modern science, and experimental falsifiability.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"937-945"},"PeriodicalIF":1.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-10-27DOI: 10.1177/27683605251392795
Thomas Ostermann, Lutz Neugebauer
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Pub Date : 2025-11-01Epub Date: 2025-06-05DOI: 10.1089/jicm.2024.0688
Qi Zhuang, Li Chen, You Yang
Aim: To systematically assess the therapeutic impact of music interventions on hypertensive disorders of pregnancy (HDP). Design: Systematic review and meta-analysis. Methods: A comprehensive search of various databases, such as PubMed, Embase, Cochrane Library, Web of Science, Scopus, CINAHL, EBSCO, Chinese National Knowledge Infrastructure, China Biomedical Literature Database, and Foreign Medical Literature Retrieval Service, was conducted to identify randomized controlled trials (RCTs) investigating the impact of music therapy on HDP from their inception through March 2024. Two independent reviewers performed study selection, data extraction, and risk-of-bias assessment using RoB 2. Statistical analyses were conducted in STATA 17, with evidence certainty graded using Grading of Recommendations Assessment, Development, and Evaluation. The protocol followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was prospectively registered in PROSPERO. Results: The meta-analysis included 14 RCTs comprising 1,477 participants. Five separate meta-analyses were conducted to compare the efficacy of music therapy versus standard care. Moderate-quality evidence from randomized trials demonstrated significant reductions associated with music therapy in systolic blood pressure (mean difference [MD] = -10.55 mmHg, 95% confidence interval [CI]: -13.86 to -7.24, p < 0.05), diastolic blood pressure (MD = -8.14 mmHg, 95% CI: -10.59 to -5.58, p < 0.05), sleep quality in patients with hypertension (MD = -1.95 points, 95% CI: -2.41 to -1.49, p < 0.05), and depression (MD = -7.80 points, 95% CI: -9.97 to -5.64, p < 0.001). Low-quality evidence suggested a modest improvement in anxiety (MD = -7.24 points, 95% CI: -8.84 to -5.64, p < 0.05). No publication bias was found in the comprehensive analysis results (all p > 0.1). Conclusion: Our systematic review suggests that adjunctive music therapy provides clinically relevant benefits for controlling systolic and diastolic blood pressure and improving psychological outcomes including anxiety, depression, and sleep quality in patients with HDP when compared with standard care alone.
目的:系统评价音乐干预对妊娠期高血压疾病(HDP)的治疗效果。设计:系统回顾和荟萃分析。方法:综合检索PubMed、Embase、Cochrane图书馆、Web of Science、Scopus、CINAHL、EBSCO、中国国家知识基础设施、中国生物医学文献数据库和国外医学文献检索服务等数据库,确定从开始到2024年3月调查音乐治疗对HDP影响的随机对照试验(RCTs)。两名独立审稿人使用RoB 2进行研究选择、数据提取和偏倚风险评估。在STATA 17中进行统计分析,使用建议评估、发展和评估分级对证据确定性进行分级。该方案遵循系统评价和荟萃分析指南的首选报告项目,并在PROSPERO进行前瞻性登记。结果:荟萃分析纳入14项随机对照试验,共1477名受试者。进行了五项独立的荟萃分析来比较音乐治疗与标准治疗的疗效。Moderate-quality来自随机试验的证据证明显著减少与音乐疗法在收缩压(平均差(MD) = -10.55毫米汞柱,95%可信区间[CI]: -13.86, -7.24, p < 0.05),舒张压(MD = -8.14毫米汞柱,95%置信区间CI: -10.59 - -5.58, p < 0.05),高血压患者的睡眠质量(MD = -1.95点,95%置信区间CI: -2.41 - -1.49, p < 0.05),和抑郁(MD = -7.80点,95%置信区间CI: -9.97 - -5.64, p < 0.001)。低质量证据显示焦虑有适度改善(MD = -7.24分,95% CI: -8.84 ~ -5.64, p < 0.05)。综合分析结果未发现发表偏倚(均p < 0.01)。结论:我们的系统综述表明,与单独的标准治疗相比,辅助音乐治疗在控制收缩压和舒张压以及改善HDP患者的心理结局(包括焦虑、抑郁和睡眠质量)方面具有临床相关的益处。
{"title":"Effects of Music Therapy on Patients with Hypertensive Disorders of Pregnancy: A Systematic Review and Meta-Analysis.","authors":"Qi Zhuang, Li Chen, You Yang","doi":"10.1089/jicm.2024.0688","DOIUrl":"10.1089/jicm.2024.0688","url":null,"abstract":"<p><p><b><i>Aim:</i></b> To systematically assess the therapeutic impact of music interventions on hypertensive disorders of pregnancy (HDP). <b><i>Design:</i></b> Systematic review and meta-analysis. <b><i>Methods:</i></b> A comprehensive search of various databases, such as PubMed, Embase, Cochrane Library, Web of Science, Scopus, CINAHL, EBSCO, Chinese National Knowledge Infrastructure, China Biomedical Literature Database, and Foreign Medical Literature Retrieval Service, was conducted to identify randomized controlled trials (RCTs) investigating the impact of music therapy on HDP from their inception through March 2024. Two independent reviewers performed study selection, data extraction, and risk-of-bias assessment using RoB 2. Statistical analyses were conducted in STATA 17, with evidence certainty graded using Grading of Recommendations Assessment, Development, and Evaluation. The protocol followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was prospectively registered in PROSPERO. <b><i>Results:</i></b> The meta-analysis included 14 RCTs comprising 1,477 participants. Five separate meta-analyses were conducted to compare the efficacy of music therapy versus standard care. Moderate-quality evidence from randomized trials demonstrated significant reductions associated with music therapy in systolic blood pressure (mean difference [MD] <i>= -</i>10.55 mmHg, 95% confidence interval [CI]: -13.86 to -7.24, <i>p</i> < 0.05), diastolic blood pressure (MD <i>= -</i>8.14 mmHg, 95% CI: -10.59 to -5.58, <i>p</i> < 0.05), sleep quality in patients with hypertension (MD <i>= -</i>1.95 points, 95% CI: -2.41 to -1.49, <i>p</i> < 0.05), and depression (MD <i>= -</i>7.80 points, 95% CI: -9.97 to -5.64, <i>p</i> < 0.001). Low-quality evidence suggested a modest improvement in anxiety (MD <i>= -</i>7.24 points, 95% CI: -8.84 to -5.64, <i>p</i> < 0.05). No publication bias was found in the comprehensive analysis results (all <i>p</i> > 0.1). <b><i>Conclusion:</i></b> Our systematic review suggests that adjunctive music therapy provides clinically relevant benefits for controlling systolic and diastolic blood pressure and improving psychological outcomes including anxiety, depression, and sleep quality in patients with HDP when compared with standard care alone.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"955-969"},"PeriodicalIF":1.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}