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Minerva Respiratory Medicine最新文献

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Should we continue to perform medical thoracoscopy in pleural tuberculosis? 胸膜结核患者是否应继续进行内科胸腔镜检查?
IF 2.4 Q4 RESPIRATORY SYSTEM Pub Date : 2020-02-01 DOI: 10.23736/s0026-4954.19.01856-x
Andi Sukthi, U. Fantoni, M. Damin
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引用次数: 0
The yellow brick road 黄砖路
IF 2.4 Q4 RESPIRATORY SYSTEM Pub Date : 2020-02-01 DOI: 10.23736/s0026-4954.19.01862-5
M. Tiné, M. Turrin, Kim Lokar-Oliani, M. Cosio, M. Saetta
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引用次数: 0
Comparison of oral disease manifestation in patients with pulmonary disease and healthy group 肺部疾病患者与健康人群口腔疾病表现的比较
IF 2.4 Q4 RESPIRATORY SYSTEM Pub Date : 2018-06-01 DOI: 10.23736/s0026-4954.18.01819-9
S. Shirazian, S. Manifar, M. Gharabaghi, Zahra Keshvari, N. Bahrami
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引用次数: 0
Respiratory function in systemic sclerosis 系统性硬化症的呼吸功能
IF 2.4 Q4 RESPIRATORY SYSTEM Pub Date : 2018-06-01 DOI: 10.23736/s0026-4954.18.01814-x
M. Ravanbakhsh, M. Nasiri, E. Rajaee, S. Goharpey
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引用次数: 0
Exhaled breath condensate in chronic obstructive pulmonary disease: methodological challenges and clinical application 慢性阻塞性肺疾病的呼出气凝析物:方法学挑战和临床应用
IF 2.4 Q4 RESPIRATORY SYSTEM Pub Date : 2018-06-01 DOI: 10.23736/S0026-4954.18.01816-3
Z. Lázár, I. Horváth, J. Vestbo, A. Bikov
Collection of exhaled breath condensate (EBC) is a non-invasive method to sample the airway lining fluid. The composi- tion of EBC may reflect physiological and pathophysiological processes within the lower airways, which could otherwise be investigated only with more invasive techniques. Hence, analysis of the condensate fluid seems feasible in chronic obstructive pulmonary disease (COPD) to monitor disease processes and facilitate personalized therapy. In the past two decades, a multitude of molecules has been assessed in EBC samples from patients with COPD, characterizing inflam- mation, oxidative and nitrative stress in this disorder. Recently, multimarker profiling with sensitive metabolomic or proteomic approaches, optimized for the EBC matrix, has also been applied, which could overcome the pitfalls of single marker detection using commercial assay systems. In this review, we describe the theoretical background of EBC formation, systematically discuss technical and methodological difficulties of sample collection and analysis and summarize data on EBC biomarkers in COPD. Finally, based on previous findings and our experience, we propose potential future directions for the EBC research community, which could pave the way for introducing EBC analysis in clinical practice. (
呼气冷凝水收集(EBC)是一种非侵入性的方法来取样气道衬里液。EBC的组成可能反映了下气道内的生理和病理生理过程,否则只能通过更具侵入性的技术来研究。因此,分析凝析液在慢性阻塞性肺疾病(COPD)中监测疾病进程和促进个性化治疗似乎是可行的。在过去的二十年中,已经在COPD患者的EBC样本中评估了大量分子,表征了这种疾病的炎症、氧化和硝化应激。最近,针对EBC基质进行优化的敏感代谢组学或蛋白质组学方法的多标记分析也得到了应用,这可以克服使用商业分析系统进行单标记检测的缺陷。在这篇综述中,我们描述了EBC形成的理论背景,系统地讨论了样本采集和分析的技术和方法难点,并总结了COPD中EBC生物标志物的数据。最后,根据以往的研究结果和我们的经验,我们提出了EBC研究界的潜在未来方向,这可能为将EBC分析引入临床实践铺平道路。(
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引用次数: 4
Subclinical thyroid disease and obstructive sleep apnea: a focus on their relationship 亚临床甲状腺疾病和阻塞性睡眠呼吸暂停:关注他们的关系
IF 2.4 Q4 RESPIRATORY SYSTEM Pub Date : 2018-06-01 DOI: 10.23736/s0026-4954.18.01813-8
C. Andaloro, I. La Mantia
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引用次数: 0
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Minerva Respiratory Medicine
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