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Cortical Mirror-System Activation During Real-Life Game Playing: An Intracranial Electroencephalography (EEG) Study 现实生活中玩游戏时皮层镜像系统的激活:颅内脑电图(EEG)研究
Pub Date : 2019-02-25 DOI: 10.32470/CCN.2018.1096-0
M. Kern, Johanna Ruescher, A. Schulze-Bonhage, T. Ball
Analogous to the mirror neuron system repeatedly described in monkeys as a possible substrate for imitation learning and/or action understanding, a neuronal execution/observation matching system (OEMS) is assumed in humans, but little is known to what extent this system is activated in non-experimental, real-life conditions. In the present case study, we investigated brain activity of this system during natural, non-experimental motor behavior as it occurred during playing of the board game "Malefiz". We compared spectral modulations of the high-gamma band related to ipsilateral reaching movement execution and observation of the same kind of movement using electrocorticography (ECoG) in one participant. Spatially coincident activity during both conditions execution and observation was recorded at electrode contacts over the premotor/primary motor cortex. The topography and amplitude of the high-gamma modulations related to both, movement observation and execution were clearly spatially correlated over several fronto-parietal brain areas. Thus, our findings indicate that a network of cortical areas contributes to the human OEMS, beyond primary/premotor cortex including Brocas area and the temporo-parieto-occipital junction area, in real-life conditions.
与在猴子中被反复描述为模仿学习和/或动作理解的可能基础的镜像神经元系统类似,在人类中假设存在神经元执行/观察匹配系统(OEMS),但很少有人知道该系统在非实验、现实条件下的激活程度。在本案例研究中,我们研究了在玩棋盘游戏“Malefiz”时,该系统在自然、非实验性运动行为中的大脑活动。我们比较了与同侧到达运动执行相关的高伽马波段的频谱调制,并使用皮质电图(ECoG)在一个参与者中观察到相同类型的运动。在条件执行和观察期间,通过电极接触记录了运动前/初级运动皮层的空间重合活动。与运动观察和执行相关的高伽马调制的地形和振幅在几个额顶叶脑区具有明显的空间相关性。因此,我们的研究结果表明,在现实生活条件下,除了初级/前运动皮层(包括Brocas区和颞顶枕交界区)外,皮层区域网络对人类原始机械制造也有贡献。
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引用次数: 2
Contribution of Social Network Analysis and Collective Phenomena to Understanding Social Complexity and Cognition 社会网络分析和集体现象对理解社会复杂性和认知的贡献
Pub Date : 2018-09-24 DOI: 10.1007/978-3-319-93776-2_8
D. Boyer, G. Ramos-Fernández
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引用次数: 2
Semantic compression of episodic memories 情景记忆的语义压缩
Pub Date : 2018-06-20 DOI: 10.32470/ccn.2018.1050-0
D. G. Nagy, B. Török, Gergő Orbán
Storing knowledge of an agent's environment in the form of a probabilistic generative model has been established as a crucial ingredient in a multitude of cognitive tasks. Perception has been formalised as probabilistic inference over the state of latent variables, whereas in decision making the model of the environment is used to predict likely consequences of actions. Such generative models have earlier been proposed to underlie semantic memory but it remained unclear if this model also underlies the efficient storage of experiences in episodic memory. We formalise the compression of episodes in the normative framework of information theory and argue that semantic memory provides the distortion function for compression of experiences. Recent advances and insights from machine learning allow us to approximate semantic compression in naturalistic domains and contrast the resulting deviations in compressed episodes with memory errors observed in the experimental literature on human memory.
以概率生成模型的形式存储智能体所处环境的知识已成为众多认知任务的关键组成部分。感知已被形式化为对潜在变量状态的概率推断,而在决策中,环境模型用于预测行动的可能后果。这种生成模型早前曾被提出作为语义记忆的基础,但目前尚不清楚这种模型是否也是情景记忆中经验有效存储的基础。我们在信息论的规范框架中形式化情节的压缩,并认为语义记忆为经验压缩提供了扭曲功能。机器学习的最新进展和见解使我们能够在自然领域中近似语义压缩,并将压缩事件的结果偏差与人类记忆实验文献中观察到的记忆错误进行对比。
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引用次数: 6
Structure from noise: Mental errors yield abstract representations of events 来自噪音的结构:心理错误产生事件的抽象表征
Pub Date : 2018-05-31 DOI: 10.32470/CCN.2018.1169-0
Christopher W. Lynn, Ari E. Kahn, D. Bassett
Humans are adept at uncovering complex associations in the world around them, yet the underlying mechanisms remain poorly understood. Intuitively, learning the higher-order structure of statistical relationships should involve sophisticated mental processes, expending valuable computational resources. Here we propose a competing perspective: that higher-order associations actually arise from natural errors in learning. Combining ideas from information theory and reinforcement learning, we derive a novel maximum entropy model of people's internal expectations about the transition structures underlying sequences of ordered events. Importantly, our model analytically accounts for previously unexplained network effects on human expectations and quantitatively describes human reaction times in probabilistic sequential motor tasks. Additionally, our model asserts that human expectations should depend critically on the different topological scales in a transition network, a prediction that we subsequently test and validate in a novel experiment. Generally, our results highlight the important role of mental errors in shaping abstract representations, and directly inspire new physically-motivated models of human behavior.
人类善于发现周围世界的复杂联系,但其潜在机制仍然知之甚少。直观地说,学习统计关系的高阶结构应该涉及复杂的心理过程,消耗宝贵的计算资源。在这里,我们提出了一个竞争性的观点:高阶联想实际上是由学习中的自然错误产生的。结合信息论和强化学习的思想,我们推导了一个新的最大熵模型,该模型描述了人们对有序事件序列下的过渡结构的内部期望。重要的是,我们的模型分析地解释了先前无法解释的网络效应对人类期望的影响,并定量地描述了人类在概率顺序运动任务中的反应时间。此外,我们的模型断言,人类的期望应该严格依赖于过渡网络中的不同拓扑尺度,我们随后在一个新的实验中测试和验证了这一预测。总的来说,我们的研究结果强调了心理错误在塑造抽象表征中的重要作用,并直接启发了新的人类行为物理动机模型。
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引用次数: 8
Consciousness and integrated energy differences in the brain 大脑中意识和综合能量的差异
Pub Date : 2018-04-27 DOI: 10.31234/osf.io/fvjt2
R. Pepperell
To understand consciousness within the framework of natural science we must acknowledge the role of energy in the brain. Many contemporary neuroscientists regard the brain as an information processor. However, evidence from brain imaging experiments demonstrates that the brain is actually a voracious consumer of energy, and that functionality is intimately tied to metabolism. Maintaining a critical level of energy in the brain is required to sustain consciousness, and the organisation of this energy distinguishes conscious from unconscious states. Meanwhile, contemporary physicists often regard energy as an abstract mathematical property. But this view neglects energy's causal efficacy and actuality, as identified by Aristotle and later appreciated by many important biologists, psychologists and physicists. By reconsidering the nature of energy and recasting its role in neural activity, we arrive at a theory of consciousness that is consistent with the laws of physics, chemistry and biology. The argument draws on the integrated information theory (IIT) developed by Tononi et al. but reinterprets their findings from the perspective of energy exchange. In IIT, the conscious state in a system, such as a brain, is defined by the quantity of integrated differences, or information, it contains. According to the approach outlined here, it is in the nature of energy to manifest differences of motion and tension. The level of complexity of the energy differences in a system determines its conscious state. Consciousness occurs because, in Nagel's terminology, there is 'something it is like' to be a sufficiently complex state of energy differences.
要在自然科学的框架内理解意识,我们必须承认能量在大脑中的作用。许多当代神经科学家认为大脑是一个信息处理器。然而,来自脑成像实验的证据表明,大脑实际上是一个贪婪的能量消耗者,其功能与新陈代谢密切相关。维持意识需要在大脑中维持一个临界水平的能量,而这种能量的组织将意识状态与无意识状态区分开来。同时,当代物理学家往往把能量看作一种抽象的数学性质。但这种观点忽视了能量的因果效应和现实性,正如亚里士多德所指出的那样,后来被许多重要的生物学家、心理学家和物理学家所赞赏。通过重新考虑能量的本质,重新定义它在神经活动中的作用,我们得出了一个与物理、化学和生物学定律一致的意识理论。该论点借鉴了托诺尼等人提出的综合信息理论(IIT),但从能源交换的角度重新解释了他们的发现。在IIT中,系统(如大脑)中的意识状态是由其包含的综合差异或信息的数量来定义的。根据这里概述的方法,能量的本质是表现出运动和紧张的差异。系统中能量差异的复杂程度决定了它的意识状态。用内格尔的术语来说,意识的产生是因为存在一种足够复杂的能量差异状态。
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引用次数: 2
Particle-filtering approaches for nonlinear Bayesian decoding of neuronal spike trains 神经元尖峰序列非线性贝叶斯解码的粒子滤波方法
Pub Date : 2018-04-25 DOI: 10.5167/UZH-168551
A. Kutschireiter, J. Pfister
The number of neurons that can be simultaneously recorded doubles every seven years. This ever increasing number of recorded neurons opens up the possibility to address new questions and extract higher dimensional stimuli from the recordings. Modeling neural spike trains as point processes, this task of extracting dynamical signals from spike trains is commonly set in the context of nonlinear filtering theory. Particle filter methods relying on importance weights are generic algorithms that solve the filtering task numerically, but exhibit a serious drawback when the problem dimensionality is high: they are known to suffer from the 'curse of dimensionality' (COD), i.e. the number of particles required for a certain performance scales exponentially with the observable dimensions. Here, we first briefly review the theory on filtering with point process observations in continuous time. Based on this theory, we investigate both analytically and numerically the reason for the COD of weighted particle filtering approaches: Similarly to particle filtering with continuous-time observations, the COD with point-process observations is due to the decay of effective number of particles, an effect that is stronger when the number of observable dimensions increases. Given the success of unweighted particle filtering approaches in overcoming the COD for continuous- time observations, we introduce an unweighted particle filter for point-process observations, the spike-based Neural Particle Filter (sNPF), and show that it exhibits a similar favorable scaling as the number of dimensions grows. Further, we derive rules for the parameters of the sNPF from a maximum likelihood approach learning. We finally employ a simple decoding task to illustrate the capabilities of the sNPF and to highlight one possible future application of our inference and learning algorithm.
可以同时记录的神经元数量每七年翻一番。记录的神经元数量不断增加,为解决新问题和从记录中提取更高维度的刺激提供了可能性。将神经脉冲序列建模为点过程,从脉冲序列中提取动态信号的任务通常设置在非线性滤波理论的背景下。依赖于重要权值的粒子滤波方法是一种用数值方法解决滤波任务的通用算法,但是当问题的维数很高时,它们表现出一个严重的缺点:它们受到“维数诅咒”(COD)的影响,即特定性能所需的粒子数量随着可观察维数呈指数级增长。本文首先简要介绍了连续时间点过程观测滤波的理论。基于这一理论,我们从解析和数值两个方面研究了加权粒子滤波方法COD的原因:与连续时间观测的粒子滤波相似,点过程观测的COD是由于有效粒子数的衰减,当可观测维数增加时,这种效应更强。鉴于非加权粒子滤波方法在克服连续时间观测的COD方面的成功,我们引入了一种用于点过程观测的非加权粒子滤波器,即基于峰值的神经粒子滤波器(sNPF),并表明它随着维数的增加而表现出类似的有利尺度。进一步,我们从极大似然方法学习中推导出sNPF参数的规则。最后,我们使用一个简单的解码任务来说明sNPF的功能,并强调我们的推理和学习算法的一个可能的未来应用。
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引用次数: 1
Scan transcription of two-dimensional shapes as an alternative neuromorphic concept 二维形状的扫描转录作为另一种神经形态概念
Pub Date : 2018-03-01 DOI: 10.36959/643/301
E. Greene, Yash J. Patel
Selfridge, along with Sutherland and Marr provided some of the earliest proposals for how to program computers to recognize shapes. Their emphasis on filtering for contour features, especially the orientation of boundary segments, was reinforced by the Nobel Prize winning work of Hubel & Wiesel who discovered that neurons in primary visual cortex selectively respond as a function of contour orientation. Countless investigators and theorists have continued to build on this approach. These models are often described as neuromorphic, which implies that the computational methods are based on biologically plausible principles. Recent work from the present lab has challenged the emphasis on orientation selectivity and the use of neural network principles. The goal of the present report is not to relitigate those issues, but to provide an alternative concept for encoding of shape information that may be useful to neuromorphic modelers.
塞尔弗里奇与萨瑟兰和马尔一起,最早提出了一些关于如何通过编程让计算机识别形状的建议。他们强调对轮廓特征的过滤,特别是边界段的方向,这一点在诺贝尔奖获得者Hubel & Wiesel的研究中得到了加强,他们发现初级视觉皮层中的神经元选择性地响应轮廓方向的函数。无数的研究者和理论家继续在这种方法的基础上进行研究。这些模型通常被描述为神经形态的,这意味着计算方法是基于生物学上合理的原理。本实验室最近的工作对强调定向选择性和使用神经网络原理提出了挑战。本报告的目的不是重新讨论这些问题,而是提供一种可能对神经形态建模者有用的形状信息编码的替代概念。
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引用次数: 5
Emergence of Fractional Kinetics in Spiny Dendrites 刺状树突中分数动力学的出现
Pub Date : 2018-01-25 DOI: 10.3390/fractalfract2010006
S. Vitali, F. Mainardi, G. Castellani
Fractional extensions of the cable equation have been proposed in the literature to describe transmembrane potential in spiny dendrites. The anomalous behavior has been related in the literature to the geometrical properties of the system, in particular, the density of spines, by experiments, computer simulations, and in comb-like models. The same PDE can be related to more than one stochastic process leading to anomalous diffusion behavior. The time-fractional diffusion equation can be associated to a continuous time random walk (CTRW) with power-law waiting time probability or to a special case of the Erdely-Kober fractional diffusion, described by the ggBm. In this work, we show that time fractional generalization of the cable equation arises naturally in the CTRW by considering a superposition of Markovian processes and in a ggBm-like construction of the random variable.
文献中提出了索方程的分数扩展来描述刺状树突的跨膜电位。在文献中,通过实验、计算机模拟和梳状模型,将异常行为与系统的几何特性,特别是棘的密度联系起来。相同的偏微分方程可以与多个导致异常扩散行为的随机过程有关。时间-分数扩散方程可以与具有幂律等待时间概率的连续时间随机漫步(CTRW)联系起来,也可以与由ggBm描述的Erdely-Kober分数扩散的特殊情况联系起来。在这项工作中,我们证明了通过考虑马尔可夫过程的叠加和随机变量的ggBm-like构造,在CTRW中自然产生了电缆方程的时间分数泛化。
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引用次数: 3
Fractal analyses of networks of integrate-and-fire stochastic spiking neurons 随机脉冲神经元网络的分形分析
Pub Date : 2018-01-19 DOI: 10.1007/978-3-319-73198-8_14
A. Costa, M. J. Amon, O. Sporns, Luis H. Favela
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引用次数: 7
Cognition and Reality 认知与现实
Pub Date : 2017-12-27 DOI: 10.13128/SUBSTANTIA-40
F. Arecchi
We discuss the two moments of human cognition, namely, apprehension (A), whereby a coherent perception emerges from the recruitment of neuronal groups, and judgment(B),that entails the comparison of two apprehensions acquired at different times, coded in a suitable language and retrieved by memory. (B) entails self-consciousness, in so far as the agent who expresses the judgment must be aware that the two apprehensions are submitted to his/her own scrutiny and that it is his/her task to extract a mutual relation. Since (B) lasts around 3 seconds, the semantic value of the pieces under comparison must be decided within that time. This implies a fast search of the memory contents. As a fact, exploring human subjects with sequences of simple words, we find evidence of a limited time window , corresponding to the memory retrieval of a linguistic item in order to match it with the next one in a text flow (be it literary, or musical,or figurative). While apprehension is globally explained as a Bayes inference, judgment tresults from an inverse Bayes inference. As a consequence, two hermeneutics emerge (called respectively circle and coil). The first one acts in a pre-assigned space of features. The second one provides the discovery of novel features, thus unveiling previously unknown aspects and hence representing the road to reality.
我们讨论了人类认知的两个时刻,即理解(A)和判断(B),即从神经元群的招募中产生连贯的感知,这需要比较在不同时间获得的两种理解,用合适的语言编码并通过记忆检索。(B)需要自我意识,就表达判断的主体而言,他/她必须意识到,这两种忧虑都是由他/她自己审查的,提取一种相互关系是他/她的任务。由于(B)大约持续3秒,因此必须在这段时间内确定被比较片段的语义价值。这意味着对内存内容的快速搜索。事实上,在用简单的单词序列探索人类主题时,我们发现了有限时间窗口的证据,对应于一个语言项目的记忆检索,以便与文本流中的下一个项目相匹配(无论是文学、音乐还是比喻)。虽然忧虑在全局上被解释为贝叶斯推理,但判断是由反贝叶斯推理产生的。因此,出现了两种解释学(分别称为圆形和线圈)。第一个在预先分配的特征空间中起作用。第二个提供了新特征的发现,从而揭示了以前未知的方面,从而代表了通往现实的道路。
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引用次数: 179
期刊
arXiv: Neurons and Cognition
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