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Cx40 Suppresses Sprouting Angiogenesis In Vitro Cx40 抑制体外萌芽血管生成
IF 2.3 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-12-01 DOI: 10.1089/bioe.2023.0034
Edward K. Looker, F. Aan, Christopher J. Hatch, Christopher C.W. Hughes, Michelle L. Matter, Jennifer S. Fang
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引用次数: 0
Deciphering Immediate Post-Pulse Membrane Resealing from 4-Electrode Impedance Measurements by Numerical Modeling 通过数值建模从 4 电极阻抗测量解密脉冲后膜立即重新闭合的过程
IF 2.3 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-12-01 DOI: 10.1089/bioe.2023.0012
Annabelle Collin, Tomás García-Sánchez, S. Corridore, Lluis M. Mir, C. Poignard
{"title":"Deciphering Immediate Post-Pulse Membrane Resealing from 4-Electrode Impedance Measurements by Numerical Modeling","authors":"Annabelle Collin, Tomás García-Sánchez, S. Corridore, Lluis M. Mir, C. Poignard","doi":"10.1089/bioe.2023.0012","DOIUrl":"https://doi.org/10.1089/bioe.2023.0012","url":null,"abstract":"","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"227 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139018581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioelectricity Reaches a Milestone! 生物电达到一个里程碑！
IF 2.3 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-12-01 DOI: 10.1089/bioe.2023.29034.editorial
Mustafa B.A. Djamgoz, Michael Levin
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引用次数: 0
Bioengineered Conductive Scaffolds for Neural Tissue Engineering 用于神经组织工程的生物工程导电支架
IF 2.3 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-11-21 DOI: 10.1089/bioe.2023.0023
Judy Senanayake, H. Sundararaghavan
{"title":"Bioengineered Conductive Scaffolds for Neural Tissue Engineering","authors":"Judy Senanayake, H. Sundararaghavan","doi":"10.1089/bioe.2023.0023","DOIUrl":"https://doi.org/10.1089/bioe.2023.0023","url":null,"abstract":"","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"38 11","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139253909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential Applications for Sublethal Pulsed Electric Field Exposures on Plant Cells and Bacteria 亚致死脉冲电场对植物细胞和细菌的潜在应用
IF 2.3 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-11-21 DOI: 10.1089/bioe.2023.0015
Zachary Brian Rosenzweig, G. L. Thompson
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引用次数: 0
Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for Bioelectricity 罗莎琳德·富兰克林协会自豪地宣布2022年生物电奖获得者
IF 2.3 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-09-04 DOI: 10.1089/bioe.2023.29032.rfs2022
Anna Tarasenko
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引用次数: 0
19th World Congress of Basic and Clinical Pharmacology, July 2nd–7th, 2023, Glasgow 第19届世界基础与临床药理学大会，2023年7月2日至7日，格拉斯哥
Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-09-01 DOI: 10.1089/bioe.2023.0029
Gary J. Stephens, Damian C. Bell
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引用次数: 0
Channel Behavior and Voltage Gating of a Cx43 Mutant Simulating Preconditioning. 模拟预处理的Cx43突变体的通道行为和电压门控。
IF 1.6 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-09-01 Epub Date: 2023-09-12 DOI: 10.1089/bioe.2023.0024
Jose F Ek-Vitorin, Diego Silva-Mendoza, Tasha K Pontifex, Janis M Burt

Background: Ischemic preconditioning induces lateralization and dephosphorylation of Connexin 43 (Cx43). However, the Cx43 protein that remains at intercalated disks may be phosphorylated by casein kinase 1 (CK1) and protein kinase C (PKC), and both kinases provide cardioprotection from further ischemic injury. Here we explore the channel characteristics of a Cx43 mutant mimicking preconditioning by CK1 and PKC phosphorylation.

Materials and methods: Whole-cell patch-clamp recordings were performed in cells expressing the mutant Cx43pc (S325,328,330,368D, S365A-Cx43), and the connexin electrical behavior was analyzed at the single channel and macroscopic level.

Results: Cx43pc hemichannels opened readily, whereas gap junctions channels displayed amplitudes between the wild-type and CK1 phosphorylated forms, and weaker voltage gating than either counterpart.

Conclusions: Ischemic preconditioning and the ensuing phosphorylation of Cx43 by PKC may render junctional channels insensitive to transjunctional voltages, allowing the preservation of intercellular communication in ischemic conditions.

背景：缺血预处理诱导连接蛋白43（Cx43）的侧化和去磷酸化。然而，保留在插入盘上的Cx43蛋白可能被酪蛋白激酶1（CK1）和蛋白激酶C（PKC）磷酸化，并且这两种激酶都提供心脏保护，防止进一步的缺血性损伤。在这里，我们探索了通过CK1和PKC磷酸化模拟预处理的Cx43突变体的通道特性。材料和方法：在表达突变体Cx43pc（S325328330368D，S365A-Cx43）的细胞中进行全细胞膜片钳记录，并在单通道和宏观水平上分析连接蛋白的电行为。结果：Cx43pc半通道很容易打开，而间隙连接通道显示出野生型和CK1磷酸化形式之间的振幅，并且电压门控比任何一种形式都弱。结论：缺血预处理和随后PKC对Cx43的磷酸化可能使连接通道对跨连接电压不敏感，从而在缺血条件下保持细胞间通讯。
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引用次数: 0
Long Range Communication via Gap Junctions and Stress in Planarian Morphogenesis: A Computational Study 涡虫形态发生中通过间隙连接和应力的远程通信:一个计算研究
Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-09-01 DOI: 10.1089/bioe.2023.0032
Marcel Blattner, Michael Levin
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引用次数: 0
Bioelectricity Buzz 生物电嗡嗡声
Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Bioelectricity
Pub Date : 2023-09-01 DOI: 10.1089/bioe.2023.0037
Ann M. Rajnicek
{"title":"Bioelectricity Buzz","authors":"Ann M. Rajnicek","doi":"10.1089/bioe.2023.0037","DOIUrl":"https://doi.org/10.1089/bioe.2023.0037","url":null,"abstract":"","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135297762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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