首页 > 最新文献

Visual Computing for Industry Biomedicine and Art最新文献

英文 中文
Application of artificial intelligence in assisting treatment of gynecologic tumors: a systematic review. 人工智能在妇科肿瘤辅助治疗中的应用综述。
IF 6 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-10-01 DOI: 10.1186/s42492-025-00201-1
Loufei Guo, Shuaitong Zhang, Hongbo Chen, Yifu Li, Yang Liu, Wancheng Liu, Qiang Wang, Zhenchao Tang, Ping Jiang, Junjie Wang

In recent years, the application of artificial intelligence (AI) in medical image analysis has drawn increasing attention in clinical studies of gynecologic tumors. This study presents the development and prospects of AI applications to assist in the treatment of gynecological oncology. The Web of Science database was screened for articles published until August 2023. "artificial intelligence," "deep learning," "machine learning," "radiomics," "radiotherapy," "chemoradiotherapy," "neoadjuvant therapy," "immunotherapy," "gynecological malignancy," "cervical carcinoma," "cervical cancer," "ovarian cancer," "endometrial cancer," "vulvar cancer," "Vaginal cancer" were used as keywords. Research articles related to AI-assisted treatment of gynecological cancers were included. A total of 317 articles were retrieved based on the search strategy, and 133 were selected by applying the inclusion and exclusion criteria, including 114 on cervical cancer, 10 on endometrial cancer, and 9 on ovarian cancer. Among the included studies, 44 (33%) focused on prognosis prediction, 24 (18%) on treatment response prediction, 13 (10%) on adverse event prediction, five (4%) on dose distribution prediction, and 47 (35%) on target volume delineation. Target volume delineation and dose prediction were performed using deep Learning methods. For the prediction of treatment response, prognosis, and adverse events, 57 studies (70%) used conventional radiomics methods, 13 (16%) used deep Learning methods, 8 (10%) used spatial-related unconventional radiomics methods, and 3 (4%) used temporal-related unconventional radiomics methods. In cervical and endometrial cancers, target prediction mostly included treatment response, overall survival, recurrence, toxicity undergoing radiotherapy, lymph node metastasis, and dose distribution. For ovarian cancer, the target prediction included platinum sensitivity and postoperative complications. The majority of the studies were single-center, retrospective, and small-scale; 101 studies (76%) had single-center data, 125 studies (94%) were retrospective, and 127 studies (95%) included Less than 500 cases. The application of AI in assisting treatment in gynecological oncology remains limited. Although the results of AI in predicting the response, prognosis, adverse events, and dose distribution in gynecological oncology are superior, it is evident that there is no validation of substantial data from multiple centers for these tasks.

近年来,人工智能(AI)在医学图像分析中的应用在妇科肿瘤的临床研究中越来越受到重视。本研究介绍了人工智能在辅助妇科肿瘤治疗中的应用进展和前景。Web of Science数据库筛选了2023年8月之前发表的文章。关键词是“人工智能”、“深度学习”、“机器学习”、“放射组学”、“放疗”、“放化疗”、“新辅助治疗”、“免疫治疗”、“妇科恶性肿瘤”、“宫颈癌”、“宫颈癌”、“卵巢癌”、“子宫内膜癌”、“外阴癌”、“阴道癌”。纳入了与人工智能辅助妇科癌症治疗相关的研究文章。根据检索策略共检索到317篇文献,应用纳入和排除标准筛选出133篇文献,其中宫颈癌114篇、子宫内膜癌10篇、卵巢癌9篇。纳入的研究中,44项(33%)研究集中于预后预测,24项(18%)研究集中于治疗反应预测,13项(10%)研究集中于不良事件预测,5项(4%)研究集中于剂量分布预测,47项(35%)研究集中于靶体积描绘。使用深度学习方法进行靶体积描绘和剂量预测。对于治疗反应、预后和不良事件的预测,57项研究(70%)使用常规放射组学方法,13项(16%)使用深度学习方法,8项(10%)使用与空间相关的非常规放射组学方法,3项(4%)使用与时间相关的非常规放射组学方法。在宫颈癌和子宫内膜癌中,目标预测主要包括治疗反应、总生存期、复发、放疗毒性、淋巴结转移和剂量分布。对于卵巢癌,目标预测包括铂敏感性和术后并发症。大多数研究为单中心、回顾性和小规模研究;101项研究(76%)为单中心数据,125项研究(94%)为回顾性研究,127项研究(95%)纳入病例少于500例。人工智能在妇科肿瘤辅助治疗中的应用仍然有限。虽然人工智能在预测妇科肿瘤的反应、预后、不良事件和剂量分布方面的结果是优越的,但很明显,没有来自多个中心的大量数据验证这些任务。
{"title":"Application of artificial intelligence in assisting treatment of gynecologic tumors: a systematic review.","authors":"Loufei Guo, Shuaitong Zhang, Hongbo Chen, Yifu Li, Yang Liu, Wancheng Liu, Qiang Wang, Zhenchao Tang, Ping Jiang, Junjie Wang","doi":"10.1186/s42492-025-00201-1","DOIUrl":"10.1186/s42492-025-00201-1","url":null,"abstract":"<p><p>In recent years, the application of artificial intelligence (AI) in medical image analysis has drawn increasing attention in clinical studies of gynecologic tumors. This study presents the development and prospects of AI applications to assist in the treatment of gynecological oncology. The Web of Science database was screened for articles published until August 2023. \"artificial intelligence,\" \"deep learning,\" \"machine learning,\" \"radiomics,\" \"radiotherapy,\" \"chemoradiotherapy,\" \"neoadjuvant therapy,\" \"immunotherapy,\" \"gynecological malignancy,\" \"cervical carcinoma,\" \"cervical cancer,\" \"ovarian cancer,\" \"endometrial cancer,\" \"vulvar cancer,\" \"Vaginal cancer\" were used as keywords. Research articles related to AI-assisted treatment of gynecological cancers were included. A total of 317 articles were retrieved based on the search strategy, and 133 were selected by applying the inclusion and exclusion criteria, including 114 on cervical cancer, 10 on endometrial cancer, and 9 on ovarian cancer. Among the included studies, 44 (33%) focused on prognosis prediction, 24 (18%) on treatment response prediction, 13 (10%) on adverse event prediction, five (4%) on dose distribution prediction, and 47 (35%) on target volume delineation. Target volume delineation and dose prediction were performed using deep Learning methods. For the prediction of treatment response, prognosis, and adverse events, 57 studies (70%) used conventional radiomics methods, 13 (16%) used deep Learning methods, 8 (10%) used spatial-related unconventional radiomics methods, and 3 (4%) used temporal-related unconventional radiomics methods. In cervical and endometrial cancers, target prediction mostly included treatment response, overall survival, recurrence, toxicity undergoing radiotherapy, lymph node metastasis, and dose distribution. For ovarian cancer, the target prediction included platinum sensitivity and postoperative complications. The majority of the studies were single-center, retrospective, and small-scale; 101 studies (76%) had single-center data, 125 studies (94%) were retrospective, and 127 studies (95%) included Less than 500 cases. The application of AI in assisting treatment in gynecological oncology remains limited. Although the results of AI in predicting the response, prognosis, adverse events, and dose distribution in gynecological oncology are superior, it is evident that there is no validation of substantial data from multiple centers for these tasks.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"23"},"PeriodicalIF":6.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and validation of a machine learning model for predicting venous thromboembolism complications following colorectal cancer surgery. 预测结直肠癌手术后静脉血栓栓塞并发症的机器学习模型的开发和验证。
IF 6 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-09-12 DOI: 10.1186/s42492-025-00204-y
Zongsheng Sun, Di Hao, Mingyu Yang, Wenzhi Wu, Hanhui Jing, Zhensong Yang, Anbang Sun, Wentao Xie, Longbo Zheng, Xixun Wang, Dongsheng Wang, Yun Lu, Guangye Tian, Shanglong Liu

Postoperative venous thromboembolism (VTE) in colorectal cancer (CRC) patients undergoing surgery results in poor prognosis. However, there are no effective tools for early screening and predicting VTE. In this study, we developed a machine learning (ML)-based model for predicting the risk of VTE following CRC surgery and tested its performance using an external dataset. A total of 3227 CRC surgery patients were enrolled from the Affiliated Hospital of Qingdao University and Yantai Yuhuangding Hospital (from January 2016 to December 2023). Subsequently, 1596 patients from the Affiliated Hospital of Qingdao University were assigned to the training set, and 716 patients from Yantai Yuhuangding Hospital were assigned to the external validation set. A model was developed and trained using six ML algorithms using the stacking ensemble technique. Moreover, all models were developed using the tenfold cross-validation on the training set, and their performance was tested using an independent external validation set. In the training set, 173 (10.8%) patients developed VTE, 163 (10.2%) patients experienced deep venous thrombosis, and 29 (1.82%) cases had pulmonary embolism (PE). In the external validation set, 85 (11.9%) cases of VTE, 83 (11.6%) cases of deep vein thrombosis, and 14 (1.96%) cases of PE were recorded. The analysis revealed that the stacking model outperformed all other models in the external validation set, achieving significantly better performance in all metrics: the area under the receiver operating characteristic curve = 0.840 (0.790-0.887), accuracy = 0.810 (0.783-0.836), specificity = 0.819 (0.790-0.848), sensitivity = 0.741 (0.652-0.825), and recall = 0.959 (0.942-0.975). The stacking model for surgical CRC patients shows promise in enabling timely clinical detection of high-risk cases. This method facilitates the prioritized implementation of prophylactic anticoagulation in confirmed high-risk individuals, thereby mitigating unnecessary pharmacological intervention in low-risk populations.

结直肠癌(CRC)手术患者术后静脉血栓栓塞(VTE)导致预后不良。然而,没有有效的工具来早期筛查和预测静脉血栓栓塞。在这项研究中,我们开发了一个基于机器学习(ML)的模型来预测CRC手术后VTE的风险,并使用外部数据集测试了其性能。2016年1月至2023年12月,青岛大学附属医院和烟台玉皇顶医院共纳入3227例结直肠癌手术患者。随后,青岛大学附属医院的1596例患者被分配到训练集,烟台玉皇顶医院的716例患者被分配到外部验证集。使用六种ML算法,使用堆叠集成技术开发和训练了一个模型。此外,所有模型都使用训练集上的十倍交叉验证来开发,并使用独立的外部验证集来测试它们的性能。在训练集中,173例(10.8%)患者发生VTE, 163例(10.2%)患者发生深静脉血栓形成,29例(1.82%)患者发生肺栓塞(PE)。外部验证集中,VTE 85例(11.9%),深静脉血栓83例(11.6%),PE 14例(1.96%)。分析结果表明,叠加模型在外部验证集中表现优于其他模型,在受试者工作特征曲线下面积= 0.840(0.790-0.887),准确度= 0.810(0.783-0.836),特异性= 0.819(0.790-0.848),灵敏度= 0.741(0.652-0.825),召回率= 0.959(0.942-0.975)。手术结直肠癌患者的堆叠模型显示出能够及时临床发现高危病例的希望。该方法有利于在确诊的高危人群中优先实施预防性抗凝,从而减少了低危人群中不必要的药物干预。
{"title":"Development and validation of a machine learning model for predicting venous thromboembolism complications following colorectal cancer surgery.","authors":"Zongsheng Sun, Di Hao, Mingyu Yang, Wenzhi Wu, Hanhui Jing, Zhensong Yang, Anbang Sun, Wentao Xie, Longbo Zheng, Xixun Wang, Dongsheng Wang, Yun Lu, Guangye Tian, Shanglong Liu","doi":"10.1186/s42492-025-00204-y","DOIUrl":"10.1186/s42492-025-00204-y","url":null,"abstract":"<p><p>Postoperative venous thromboembolism (VTE) in colorectal cancer (CRC) patients undergoing surgery results in poor prognosis. However, there are no effective tools for early screening and predicting VTE. In this study, we developed a machine learning (ML)-based model for predicting the risk of VTE following CRC surgery and tested its performance using an external dataset. A total of 3227 CRC surgery patients were enrolled from the Affiliated Hospital of Qingdao University and Yantai Yuhuangding Hospital (from January 2016 to December 2023). Subsequently, 1596 patients from the Affiliated Hospital of Qingdao University were assigned to the training set, and 716 patients from Yantai Yuhuangding Hospital were assigned to the external validation set. A model was developed and trained using six ML algorithms using the stacking ensemble technique. Moreover, all models were developed using the tenfold cross-validation on the training set, and their performance was tested using an independent external validation set. In the training set, 173 (10.8%) patients developed VTE, 163 (10.2%) patients experienced deep venous thrombosis, and 29 (1.82%) cases had pulmonary embolism (PE). In the external validation set, 85 (11.9%) cases of VTE, 83 (11.6%) cases of deep vein thrombosis, and 14 (1.96%) cases of PE were recorded. The analysis revealed that the stacking model outperformed all other models in the external validation set, achieving significantly better performance in all metrics: the area under the receiver operating characteristic curve = 0.840 (0.790-0.887), accuracy = 0.810 (0.783-0.836), specificity = 0.819 (0.790-0.848), sensitivity = 0.741 (0.652-0.825), and recall = 0.959 (0.942-0.975). The stacking model for surgical CRC patients shows promise in enabling timely clinical detection of high-risk cases. This method facilitates the prioritized implementation of prophylactic anticoagulation in confirmed high-risk individuals, thereby mitigating unnecessary pharmacological intervention in low-risk populations.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"22"},"PeriodicalIF":6.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12425853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lightweight and mobile artificial intelligence and immersive technologies in aviation. 航空领域的轻量化移动人工智能和沉浸式技术。
IF 6 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-09-03 DOI: 10.1186/s42492-025-00203-z
Graham Wild, Aziida Nanyonga, Anam Iqbal, Shehar Bano, Alexander Somerville, Luke Pollock

This review examines the current applications, benefits, challenges, and future potential of artificial intelligence (AI) and immersive aviation technologies. AI has been applied across various domains, including flight operations, air traffic control, maintenance, and ground handling. AI enhances aviation safety by enabling pilot assistance systems, mitigating human error, streamlining safety management systems, and aiding in accident analysis. Lightweight AI models are crucial for mobile applications in aviation, particularly for resource-constrained environments such as drones. Hardware considerations involve trade-offs between energy-efficient field-programmable gate arrays and power-consuming graphics processing units. Battery and thermal management are critical for mobile device applications. Although AI integration has numerous benefits, including enhanced safety, improved efficiency, and reduced environmental impact, it also presents challenges. Addressing algorithmic bias, ensuring cybersecurity, and managing the relationship between human operators and AI systems are crucial. The future of aviation will likely involve even more sophisticated AI algorithms, advanced hardware, and increased integration of AI with augmented reality and virtual reality, creating new possibilities for training and operations, and ultimately leading to a safer, more efficient, and more sustainable aviation industry.

本文综述了人工智能(AI)和沉浸式航空技术的当前应用、优势、挑战和未来潜力。人工智能已经应用于各个领域,包括飞行操作、空中交通管制、维修和地面处理。人工智能通过启用飞行员辅助系统、减少人为错误、简化安全管理系统和协助事故分析来提高航空安全。轻型人工智能模型对于航空领域的移动应用至关重要,尤其是在无人机等资源受限的环境中。硬件方面的考虑涉及节能现场可编程门阵列和功耗图形处理单元之间的权衡。电池和热管理对移动设备应用至关重要。尽管人工智能集成有许多好处,包括增强安全性、提高效率和减少环境影响,但它也带来了挑战。解决算法偏差、确保网络安全以及管理人类操作员与人工智能系统之间的关系至关重要。航空的未来可能会涉及更复杂的人工智能算法、先进的硬件,以及人工智能与增强现实和虚拟现实的更多整合,为培训和运营创造新的可能性,最终形成一个更安全、更高效、更可持续的航空业。
{"title":"Lightweight and mobile artificial intelligence and immersive technologies in aviation.","authors":"Graham Wild, Aziida Nanyonga, Anam Iqbal, Shehar Bano, Alexander Somerville, Luke Pollock","doi":"10.1186/s42492-025-00203-z","DOIUrl":"10.1186/s42492-025-00203-z","url":null,"abstract":"<p><p>This review examines the current applications, benefits, challenges, and future potential of artificial intelligence (AI) and immersive aviation technologies. AI has been applied across various domains, including flight operations, air traffic control, maintenance, and ground handling. AI enhances aviation safety by enabling pilot assistance systems, mitigating human error, streamlining safety management systems, and aiding in accident analysis. Lightweight AI models are crucial for mobile applications in aviation, particularly for resource-constrained environments such as drones. Hardware considerations involve trade-offs between energy-efficient field-programmable gate arrays and power-consuming graphics processing units. Battery and thermal management are critical for mobile device applications. Although AI integration has numerous benefits, including enhanced safety, improved efficiency, and reduced environmental impact, it also presents challenges. Addressing algorithmic bias, ensuring cybersecurity, and managing the relationship between human operators and AI systems are crucial. The future of aviation will likely involve even more sophisticated AI algorithms, advanced hardware, and increased integration of AI with augmented reality and virtual reality, creating new possibilities for training and operations, and ultimately leading to a safer, more efficient, and more sustainable aviation industry.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"21"},"PeriodicalIF":6.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal dynamic hierarchical clustering model for post-stroke cognitive impairment prediction. 脑卒中后认知障碍预测的多模态动态分层聚类模型。
IF 6 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-09-01 DOI: 10.1186/s42492-025-00202-0
Chen Bai, Tan Li, Yanyan Zheng, Gang Yuan, Jian Zheng, Hui Zhao

Post-stroke cognitive impairment (PSCI) is a common and debilitating consequence of stroke that often arises from complex interactions between diverse brain alterations. The accurate early prediction of PSCI is critical for guiding personalized interventions. However, existing methods often struggle to capture complex structural disruptions and integrate multimodal information effectively. This study proposes the multimodal dynamic hierarchical clustering network (MDHCNet), a graph neural network designed for accurate and interpretable PSCI prediction. MDHCNet constructs brain graphs from diffusion-weighted imaging, magnetic resonance angiography, and T1- and T2-weighted images and integrates them with clinical features using a hierarchical cross-modal fusion module. Experimental results using a real-world stroke cohort demonstrated that MDHCNet consistently outperformed deep learning baselines. Ablation studies validated the benefits of multimodal fusion, while saliency-based interpretation highlighted discriminative brain regions associated with cognitive decline. These findings suggest that MDHCNet is an effective and explainable tool for early PSCI prediction, with the potential to support individualized clinical decision-making in stroke rehabilitation.

脑卒中后认知障碍(PSCI)是脑卒中后常见的衰弱性后果,通常由多种脑改变之间的复杂相互作用引起。准确的早期预测PSCI对指导个性化干预至关重要。然而,现有的方法往往难以捕获复杂的结构破坏和有效地整合多模式信息。本文提出了多模态动态分层聚类网络(MDHCNet),这是一种用于准确和可解释PSCI预测的图神经网络。MDHCNet从弥散加权成像、磁共振血管成像以及T1和t2加权图像构建脑图,并使用分层跨模态融合模块将其与临床特征整合。使用真实中风队列的实验结果表明,MDHCNet始终优于深度学习基线。消融研究证实了多模态融合的益处,而基于显著性的解释强调了与认知能力下降相关的判别性脑区。这些发现表明MDHCNet是一种有效且可解释的早期PSCI预测工具,具有支持卒中康复个体化临床决策的潜力。
{"title":"Multimodal dynamic hierarchical clustering model for post-stroke cognitive impairment prediction.","authors":"Chen Bai, Tan Li, Yanyan Zheng, Gang Yuan, Jian Zheng, Hui Zhao","doi":"10.1186/s42492-025-00202-0","DOIUrl":"10.1186/s42492-025-00202-0","url":null,"abstract":"<p><p>Post-stroke cognitive impairment (PSCI) is a common and debilitating consequence of stroke that often arises from complex interactions between diverse brain alterations. The accurate early prediction of PSCI is critical for guiding personalized interventions. However, existing methods often struggle to capture complex structural disruptions and integrate multimodal information effectively. This study proposes the multimodal dynamic hierarchical clustering network (MDHCNet), a graph neural network designed for accurate and interpretable PSCI prediction. MDHCNet constructs brain graphs from diffusion-weighted imaging, magnetic resonance angiography, and T1- and T2-weighted images and integrates them with clinical features using a hierarchical cross-modal fusion module. Experimental results using a real-world stroke cohort demonstrated that MDHCNet consistently outperformed deep learning baselines. Ablation studies validated the benefits of multimodal fusion, while saliency-based interpretation highlighted discriminative brain regions associated with cognitive decline. These findings suggest that MDHCNet is an effective and explainable tool for early PSCI prediction, with the potential to support individualized clinical decision-making in stroke rehabilitation.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"20"},"PeriodicalIF":6.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning radiomics of elastography for diagnosing compensated advanced chronic liver disease: an international multicenter study. 弹性成像的深度学习放射组学诊断代偿晚期慢性肝病:一项国际多中心研究。
IF 6 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-08-15 DOI: 10.1186/s42492-025-00199-6
Xue Lu, Haoyan Zhang, Hidekatsu Kuroda, Matteo Garcovich, Victor de Ledinghen, Ivica Grgurević, Runze Linghu, Hong Ding, Jiandong Chang, Min Wu, Cheng Feng, Xinping Ren, Changzhu Liu, Tao Song, Fankun Meng, Yao Zhang, Ye Fang, Sumei Ma, Jinfen Wang, Xiaolong Qi, Jie Tian, Xin Yang, Jie Ren, Ping Liang, Kun Wang

Accurate, noninvasive diagnosis of compensated advanced chronic liver disease (cACLD) is essential for effective clinical management but remains challenging. This study aimed to develop a deep learning-based radiomics model using international multicenter data and to evaluate its performance by comparing it to the two-dimensional shear wave elastography (2D-SWE) cut-off method covering multiple countries or regions, etiologies, and ultrasound device manufacturers. This retrospective study included 1937 adult patients with chronic liver disease due to hepatitis B, hepatitis C, or metabolic dysfunction-associated steatotic liver disease. All patients underwent 2D-SWE imaging and liver biopsy at 17 centers across China, Japan, and Europe using devices from three manufacturers (SuperSonic Imagine, General Electric, and Mindray). The proposed generalized deep learning radiomics of elastography model integrated both elastographic images and liver stiffness measurements and was trained and tested on stratified internal and external datasets. A total of 1937 patients with 9472 2D-SWE images were included in the statistical analysis. Compared to 2D-SWE, the model achieved a higher area under the receiver operating characteristic curve (AUC) (0.89 vs 0.83, P = 0.025). It also achieved a highly consistent diagnosis across all subanalyses (P values: 0.21-0.91), whereas 2D-SWE exhibited different AUCs in the country or region (P < 0.001) and etiology (P = 0.005) subanalyses but not in the manufacturer subanalysis (P = 0.24). The model demonstrated more accurate and robust performance in noninvasive cACLD diagnosis than 2D-SWE across different countries or regions, etiologies, and manufacturers.

代偿性晚期慢性肝病(cACLD)的准确、无创诊断对于有效的临床治疗至关重要,但仍然具有挑战性。本研究旨在利用国际多中心数据开发基于深度学习的放射组学模型,并通过将其与涵盖多个国家或地区、病因和超声设备制造商的二维剪切波弹性成像(2D-SWE)截止方法进行比较来评估其性能。这项回顾性研究纳入了1937例由乙型肝炎、丙型肝炎或代谢功能障碍相关的脂肪变性肝病引起的慢性肝病成年患者。所有患者在中国、日本和欧洲的17个中心接受了2D-SWE成像和肝脏活检,使用的设备来自三家制造商(SuperSonic Imagine、General Electric和Mindray)。所提出的广义深度学习放射组学弹性成像模型集成了弹性成像图像和肝脏刚度测量,并在分层的内部和外部数据集上进行了训练和测试。统计分析共纳入1937例患者9472张2D-SWE图像。与2D-SWE相比,该模型在受者工作特征曲线(AUC)下的面积更高(0.89 vs 0.83, P = 0.025)。它还在所有亚分析中实现了高度一致的诊断(P值:0.21-0.91),而2D-SWE在国家或地区表现出不同的auc (P
{"title":"Deep learning radiomics of elastography for diagnosing compensated advanced chronic liver disease: an international multicenter study.","authors":"Xue Lu, Haoyan Zhang, Hidekatsu Kuroda, Matteo Garcovich, Victor de Ledinghen, Ivica Grgurević, Runze Linghu, Hong Ding, Jiandong Chang, Min Wu, Cheng Feng, Xinping Ren, Changzhu Liu, Tao Song, Fankun Meng, Yao Zhang, Ye Fang, Sumei Ma, Jinfen Wang, Xiaolong Qi, Jie Tian, Xin Yang, Jie Ren, Ping Liang, Kun Wang","doi":"10.1186/s42492-025-00199-6","DOIUrl":"10.1186/s42492-025-00199-6","url":null,"abstract":"<p><p>Accurate, noninvasive diagnosis of compensated advanced chronic liver disease (cACLD) is essential for effective clinical management but remains challenging. This study aimed to develop a deep learning-based radiomics model using international multicenter data and to evaluate its performance by comparing it to the two-dimensional shear wave elastography (2D-SWE) cut-off method covering multiple countries or regions, etiologies, and ultrasound device manufacturers. This retrospective study included 1937 adult patients with chronic liver disease due to hepatitis B, hepatitis C, or metabolic dysfunction-associated steatotic liver disease. All patients underwent 2D-SWE imaging and liver biopsy at 17 centers across China, Japan, and Europe using devices from three manufacturers (SuperSonic Imagine, General Electric, and Mindray). The proposed generalized deep learning radiomics of elastography model integrated both elastographic images and liver stiffness measurements and was trained and tested on stratified internal and external datasets. A total of 1937 patients with 9472 2D-SWE images were included in the statistical analysis. Compared to 2D-SWE, the model achieved a higher area under the receiver operating characteristic curve (AUC) (0.89 vs 0.83, P = 0.025). It also achieved a highly consistent diagnosis across all subanalyses (P values: 0.21-0.91), whereas 2D-SWE exhibited different AUCs in the country or region (P < 0.001) and etiology (P = 0.005) subanalyses but not in the manufacturer subanalysis (P = 0.24). The model demonstrated more accurate and robust performance in noninvasive cACLD diagnosis than 2D-SWE across different countries or regions, etiologies, and manufacturers.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"19"},"PeriodicalIF":6.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12354435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144856587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Graph neural network-tracker: a graph neural network-based multi-sensor fusion framework for robust unmanned aerial vehicle tracking. 图神经网络跟踪器:一种基于图神经网络的多传感器融合框架,用于鲁棒无人机跟踪。
IF 3.2 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-07-16 DOI: 10.1186/s42492-025-00200-2
Karim Dabbabi, Tijeni Delleji

Unmanned aerial vehicle (UAV) tracking is a critical task in surveillance, security, and autonomous navigation applications. In this study, we propose graph neural network-tracker (GNN-tracker), a novel GNN-based UAV tracking framework that effectively integrates graph-based spatial-temporal modelling, Transformer-based feature extraction, and multi-sensor fusion to enhance tracking robustness and accuracy. Unlike traditional tracking approaches, GNN-tracker dynamically constructs a spatiotemporal graph representation, improving identity consistency and reducing tracking errors under OCC-heavy scenarios. Experimental evaluations on optical, thermal, and fused UAV datasets demonstrate the superiority of GNN-tracker (fused) over state-of-the-art methods. The proposed model achieves multiple object tracking accuracy (MOTA) scores of 91.4% (fused), 89.1% (optical), and 86.3% (thermal), surpassing TransT by 8.9% in MOTA and 7.7% in higher order tracking accuracy (HOTA). The HOTA scores of 82.3% (fused), 80.1% (optical), and 78.7% (thermal) validate its strong object association capabilities, while its frames per second of 58.9 (fused), 56.8 (optical), and 54.3 (thermal) ensures real-time performance. Additionally, ablation studies confirm the essential role of graph-based modelling and multi-sensor fusion, with performance drops of up to 8.9% in MOTA when these components are removed. Thus, GNN-tracker (fused) offers a highly accurate, robust, and efficient UAV tracking solution, effectively addressing real-world challenges across diverse environmental conditions and multiple sensor modalities.

无人机(UAV)跟踪是监视、安全和自主导航应用中的一项关键任务。在这项研究中,我们提出了一种新的基于gnn的无人机跟踪框架——图神经网络跟踪器(GNN-tracker),该框架有效地集成了基于图的时空建模、基于变压器的特征提取和多传感器融合,以提高跟踪的鲁棒性和准确性。与传统的跟踪方法不同,GNN-tracker动态构建了一个时空图表示,提高了身份一致性,减少了occ重场景下的跟踪误差。对光学、热和融合无人机数据集的实验评估表明,gnn跟踪器(融合)优于最先进的方法。该模型的多目标跟踪精度(MOTA)得分分别为91.4%(融合)、89.1%(光学)和86.3%(热),在MOTA和高阶跟踪精度(HOTA)方面分别比TransT高8.9%和7.7%。82.3%(融合),80.1%(光学)和78.7%(热)的HOTA分数验证了其强大的对象关联能力,而每秒58.9帧(融合),56.8帧(光学)和54.3帧(热)确保了实时性。此外,消融研究证实了基于图形的建模和多传感器融合的重要作用,当这些组件被移除时,MOTA的性能下降高达8.9%。因此,gnn跟踪器(融合)提供了一种高度精确、鲁棒和高效的无人机跟踪解决方案,有效地解决了不同环境条件和多种传感器模式下的现实挑战。
{"title":"Graph neural network-tracker: a graph neural network-based multi-sensor fusion framework for robust unmanned aerial vehicle tracking.","authors":"Karim Dabbabi, Tijeni Delleji","doi":"10.1186/s42492-025-00200-2","DOIUrl":"10.1186/s42492-025-00200-2","url":null,"abstract":"<p><p>Unmanned aerial vehicle (UAV) tracking is a critical task in surveillance, security, and autonomous navigation applications. In this study, we propose graph neural network-tracker (GNN-tracker), a novel GNN-based UAV tracking framework that effectively integrates graph-based spatial-temporal modelling, Transformer-based feature extraction, and multi-sensor fusion to enhance tracking robustness and accuracy. Unlike traditional tracking approaches, GNN-tracker dynamically constructs a spatiotemporal graph representation, improving identity consistency and reducing tracking errors under OCC-heavy scenarios. Experimental evaluations on optical, thermal, and fused UAV datasets demonstrate the superiority of GNN-tracker (fused) over state-of-the-art methods. The proposed model achieves multiple object tracking accuracy (MOTA) scores of 91.4% (fused), 89.1% (optical), and 86.3% (thermal), surpassing TransT by 8.9% in MOTA and 7.7% in higher order tracking accuracy (HOTA). The HOTA scores of 82.3% (fused), 80.1% (optical), and 78.7% (thermal) validate its strong object association capabilities, while its frames per second of 58.9 (fused), 56.8 (optical), and 54.3 (thermal) ensures real-time performance. Additionally, ablation studies confirm the essential role of graph-based modelling and multi-sensor fusion, with performance drops of up to 8.9% in MOTA when these components are removed. Thus, GNN-tracker (fused) offers a highly accurate, robust, and efficient UAV tracking solution, effectively addressing real-world challenges across diverse environmental conditions and multiple sensor modalities.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"18"},"PeriodicalIF":3.2,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Placenta segmentation redefined: review of deep learning integration of magnetic resonance imaging and ultrasound imaging. 胎盘分割的重新定义:磁共振成像和超声成像的深度学习集成综述。
IF 3.2 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-07-15 DOI: 10.1186/s42492-025-00197-8
Asmaa Jittou, Khalid El Fazazy, Jamal Riffi

Placental segmentation is critical for the quantitative analysis of prenatal imaging applications. However, segmenting the placenta using magnetic resonance imaging (MRI) and ultrasound is challenging because of variations in fetal position, dynamic placental development, and image quality. Most segmentation methods define regions of interest with different shapes and intensities, encompassing the entire placenta or specific structures. Recently, deep learning has emerged as a key approach that offer high segmentation performance across diverse datasets. This review focuses on the recent advances in deep learning techniques for placental segmentation in medical imaging, specifically MRI and ultrasound modalities, and cover studies from 2019 to 2024. This review synthesizes recent research, expand knowledge in this innovative area, and highlight the potential of deep learning approaches to significantly enhance prenatal diagnostics. These findings emphasize the importance of selecting appropriate imaging modalities and model architectures tailored to specific clinical scenarios. In addition, integrating both MRI and ultrasound can enhance segmentation performance by leveraging complementary information. This review also discusses the challenges associated with the high costs and limited availability of advanced imaging technologies. It provides insights into the current state of placental segmentation techniques and their implications for improving maternal and fetal health outcomes, underscoring the transformative impact of deep learning on prenatal diagnostics.

胎盘分割是产前成像应用定量分析的关键。然而,由于胎儿位置、动态胎盘发育和图像质量的变化,使用磁共振成像(MRI)和超声分割胎盘是具有挑战性的。大多数分割方法用不同的形状和强度定义感兴趣的区域,包括整个胎盘或特定结构。最近,深度学习已经成为跨不同数据集提供高分割性能的关键方法。本文重点介绍了医学成像中胎盘分割的深度学习技术的最新进展,特别是MRI和超声模式,并涵盖了2019年至2024年的研究。这篇综述综合了最近的研究,扩大了这一创新领域的知识,并强调了深度学习方法在显著增强产前诊断方面的潜力。这些发现强调了选择合适的成像方式和适合特定临床情况的模型架构的重要性。此外,融合MRI和超声可以利用互补信息增强分割性能。本综述还讨论了与高成本和先进成像技术有限可用性相关的挑战。它提供了对胎盘分割技术现状及其对改善孕产妇和胎儿健康结果的影响的见解,强调了深度学习对产前诊断的变革性影响。
{"title":"Placenta segmentation redefined: review of deep learning integration of magnetic resonance imaging and ultrasound imaging.","authors":"Asmaa Jittou, Khalid El Fazazy, Jamal Riffi","doi":"10.1186/s42492-025-00197-8","DOIUrl":"10.1186/s42492-025-00197-8","url":null,"abstract":"<p><p>Placental segmentation is critical for the quantitative analysis of prenatal imaging applications. However, segmenting the placenta using magnetic resonance imaging (MRI) and ultrasound is challenging because of variations in fetal position, dynamic placental development, and image quality. Most segmentation methods define regions of interest with different shapes and intensities, encompassing the entire placenta or specific structures. Recently, deep learning has emerged as a key approach that offer high segmentation performance across diverse datasets. This review focuses on the recent advances in deep learning techniques for placental segmentation in medical imaging, specifically MRI and ultrasound modalities, and cover studies from 2019 to 2024. This review synthesizes recent research, expand knowledge in this innovative area, and highlight the potential of deep learning approaches to significantly enhance prenatal diagnostics. These findings emphasize the importance of selecting appropriate imaging modalities and model architectures tailored to specific clinical scenarios. In addition, integrating both MRI and ultrasound can enhance segmentation performance by leveraging complementary information. This review also discusses the challenges associated with the high costs and limited availability of advanced imaging technologies. It provides insights into the current state of placental segmentation techniques and their implications for improving maternal and fetal health outcomes, underscoring the transformative impact of deep learning on prenatal diagnostics.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"17"},"PeriodicalIF":3.2,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Active interaction strategy generation for human-robot collaboration based on trust. 基于信任的人机协作主动交互策略生成。
IF 3.2 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-06-23 DOI: 10.1186/s42492-025-00198-7
Yujie Guo, Pengfei Yi, Xiaopeng Wei, Dongsheng Zhou

In human-robot collaborative tasks, human trust in robots can reduce resistance to them, thereby increasing the success rate of task execution. However, most existing studies have focused on improving the success rate of human-robot collaboration (HRC) rather than on enhancing collaboration efficiency. To improve the overall collaboration efficiency while maintaining a high success rate, this study proposes an active interaction strategy generation for HRC based on trust. First, a trust-based optimal robot strategy generation method was proposed to generate the robot's optimal strategy in a HRC. This method employs a tree to model the HRC process under different robot strategies and calculates the optimal strategy based on the modeling results for the robot to execute. Second, the robot's performance was evaluated to calculate human's trust in a robot. A robot performance evaluation method based on a visual language model was also proposed. The evaluation results were input into the trust model to compute human's current trust. Finally, each time an object operation was completed, the robot's performance evaluation and optimal strategy generation methods worked together to automatically generate the optimal strategy of the robot for the next step until the entire collaborative task was completed. The experimental results demonstrates that this method significantly improve collaborative efficiency, achieving a high success rate in HRC.

在人机协作任务中,人类对机器人的信任可以减少对机器人的阻力,从而提高任务执行的成功率。然而,现有的研究大多侧重于提高人机协作的成功率(HRC),而不是提高协作效率。为了在保持高成功率的同时提高整体协作效率,本研究提出了一种基于信任的HRC主动交互策略生成。首先,提出了一种基于信任的机器人最优策略生成方法,用于生成HRC中机器人的最优策略。该方法采用树状模型对不同机器人策略下的HRC过程进行建模,并根据建模结果计算出机器人执行的最优策略。其次,评估机器人的性能,计算人类对机器人的信任程度。提出了一种基于视觉语言模型的机器人性能评价方法。将评价结果输入到信任模型中,计算人的当前信任。最后,每次完成一个目标操作,机器人的性能评估方法和最优策略生成方法共同作用,自动生成下一步机器人的最优策略,直到整个协同任务完成。实验结果表明,该方法显著提高了协同效率,在HRC中实现了较高的成功率。
{"title":"Active interaction strategy generation for human-robot collaboration based on trust.","authors":"Yujie Guo, Pengfei Yi, Xiaopeng Wei, Dongsheng Zhou","doi":"10.1186/s42492-025-00198-7","DOIUrl":"10.1186/s42492-025-00198-7","url":null,"abstract":"<p><p>In human-robot collaborative tasks, human trust in robots can reduce resistance to them, thereby increasing the success rate of task execution. However, most existing studies have focused on improving the success rate of human-robot collaboration (HRC) rather than on enhancing collaboration efficiency. To improve the overall collaboration efficiency while maintaining a high success rate, this study proposes an active interaction strategy generation for HRC based on trust. First, a trust-based optimal robot strategy generation method was proposed to generate the robot's optimal strategy in a HRC. This method employs a tree to model the HRC process under different robot strategies and calculates the optimal strategy based on the modeling results for the robot to execute. Second, the robot's performance was evaluated to calculate human's trust in a robot. A robot performance evaluation method based on a visual language model was also proposed. The evaluation results were input into the trust model to compute human's current trust. Finally, each time an object operation was completed, the robot's performance evaluation and optimal strategy generation methods worked together to automatically generate the optimal strategy of the robot for the next step until the entire collaborative task was completed. The experimental results demonstrates that this method significantly improve collaborative efficiency, achieving a high success rate in HRC.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"16"},"PeriodicalIF":3.2,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12185789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avatars in the educational metaverse. 教育虚拟世界中的化身。
IF 3.2 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-06-10 DOI: 10.1186/s42492-025-00196-9
Md Zabirul Islam, Ge Wang

Avatars in the educational metaverse are revolutionizing the learning process by providing interactive and effective learning experiences. These avatars enable students to engage in realistic scenarios, work in groups, and develop essential skills using adaptive and intelligent technologies. The purpose of this review is to evaluate the contribution of avatars to education. It investigated the use of avatars to enhance learning by offering individualized experiences and supporting collaborative group activities in virtual environments. It also analyzed the recent progress in artificial intelligence, especially natural language processing and generative models, which have significantly improved avatar capabilities. In addition, it reviewed their use in customized learning, contextual teaching, and virtual simulations to improve student participation and achievement. This study also highlighted issues impacting its implementation, including data security, ethical concerns, and limited infrastructure. The paper ends with implications and recommendations for future research in this field.

教育虚拟世界中的虚拟角色通过提供互动和有效的学习体验,正在彻底改变学习过程。这些虚拟角色使学生能够参与现实场景,在小组中工作,并使用自适应和智能技术开发基本技能。本综述的目的是评估虚拟角色对教育的贡献。它调查了虚拟角色的使用,通过提供个性化的体验和支持虚拟环境中的协作小组活动来增强学习。它还分析了人工智能的最新进展,特别是自然语言处理和生成模型,它们显著提高了虚拟角色的能力。此外,它回顾了它们在定制学习,情境教学和虚拟模拟中的应用,以提高学生的参与度和成就。该研究还强调了影响其实施的问题,包括数据安全、道德问题和有限的基础设施。文章最后对该领域未来的研究提出了启示和建议。
{"title":"Avatars in the educational metaverse.","authors":"Md Zabirul Islam, Ge Wang","doi":"10.1186/s42492-025-00196-9","DOIUrl":"10.1186/s42492-025-00196-9","url":null,"abstract":"<p><p>Avatars in the educational metaverse are revolutionizing the learning process by providing interactive and effective learning experiences. These avatars enable students to engage in realistic scenarios, work in groups, and develop essential skills using adaptive and intelligent technologies. The purpose of this review is to evaluate the contribution of avatars to education. It investigated the use of avatars to enhance learning by offering individualized experiences and supporting collaborative group activities in virtual environments. It also analyzed the recent progress in artificial intelligence, especially natural language processing and generative models, which have significantly improved avatar capabilities. In addition, it reviewed their use in customized learning, contextual teaching, and virtual simulations to improve student participation and achievement. This study also highlighted issues impacting its implementation, including data security, ethical concerns, and limited infrastructure. The paper ends with implications and recommendations for future research in this field.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"15"},"PeriodicalIF":3.2,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic prediction model based on X-rays predicting anterior cruciate ligament function in patients with knee osteoarthritis. 基于x线预测膝关节骨关节炎患者前交叉韧带功能的x线预测模型。
IF 3.2 4区 计算机科学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2025-06-06 DOI: 10.1186/s42492-025-00195-w
Guanghan Gao, Yaonan Zhang, Lei Shi, Lin Wang, Fei Wang, Qingyun Xue

Knee osteoarthritis (KOA) is a prevalent chronic condition in the elderly and is often associated with instability caused by anterior cruciate ligament (ACL) degeneration. The functional integrity of ACL is crucial for the diagnosis and treatment of KOA. Radiographic imaging is a practical diagnostic tool for predicting the functional status of the ACL. However, the precision of the current evaluation methodologies remains suboptimal. Consequently, we aimed to identify additional radiographic features from X-ray images that could predict the ACL function in a larger cohort of patients with KOA. A retrospective analysis was conducted on 272 patients whose ACL function was verified intraoperatively between October 2021 and October 2024. The patients were categorized into ACL-functional and ACL-dysfunctional groups. Using least absolute shrinkage and selection operator regression and logistic regression, four significant radiographic predictors were identified: location of the deepest wear on the medial tibial plateau (middle and posterior), wear depth in the posterior third of the medial tibial plateau (> 1.40 mm), posterior tibial slope (PTS > 7.90°), and static anterior tibial translation (> 4.49 mm). A clinical prediction model was developed and visualized using a nomogram with calibration curves and receiver operating characteristic analysis to confirm the model performance. The prediction model demonstrated great discriminative ability, showing area under the curve values of 0.831 (88.4% sensitivity, 63.8% specificity) and 0.907 (86.1% sensitivity, 82.2% specificity) in the training and validation cohorts, respectively. Consequently, the authors established an efficient approach for accurate evaluation of ACL function in KOA patients.

膝关节骨性关节炎(KOA)是老年人常见的慢性疾病,通常与前交叉韧带(ACL)变性引起的不稳定有关。前交叉韧带的功能完整性对KOA的诊断和治疗至关重要。影像学是预测前交叉韧带功能状态的实用诊断工具。然而,目前评价方法的精度仍然不够理想。因此,我们的目的是从x线图像中确定可以预测更大队列KOA患者ACL功能的其他放射学特征。回顾性分析了2021年10月至2024年10月期间术中验证ACL功能的272例患者。将患者分为acl功能组和acl功能不全组。使用最小绝对收缩、选择操作者回归和逻辑回归,确定了四个重要的放射学预测指标:胫骨内侧平台最深磨损的位置(中部和后部)、胫骨内侧平台后三分之一的磨损深度(> 1.40 mm)、胫骨后斜度(PTS > 7.90°)和胫骨前静态平移(> 4.49 mm)。建立了一个临床预测模型,并使用带有校准曲线的nomogram和receiver operating characteristic analysis来验证模型的性能。该预测模型具有较强的判别能力,在训练组和验证组的曲线下面积分别为0.831(敏感性88.4%,特异性63.8%)和0.907(敏感性86.1%,特异性82.2%)。因此,作者建立了一种有效的方法来准确评估KOA患者的ACL功能。
{"title":"Radiographic prediction model based on X-rays predicting anterior cruciate ligament function in patients with knee osteoarthritis.","authors":"Guanghan Gao, Yaonan Zhang, Lei Shi, Lin Wang, Fei Wang, Qingyun Xue","doi":"10.1186/s42492-025-00195-w","DOIUrl":"10.1186/s42492-025-00195-w","url":null,"abstract":"<p><p>Knee osteoarthritis (KOA) is a prevalent chronic condition in the elderly and is often associated with instability caused by anterior cruciate ligament (ACL) degeneration. The functional integrity of ACL is crucial for the diagnosis and treatment of KOA. Radiographic imaging is a practical diagnostic tool for predicting the functional status of the ACL. However, the precision of the current evaluation methodologies remains suboptimal. Consequently, we aimed to identify additional radiographic features from X-ray images that could predict the ACL function in a larger cohort of patients with KOA. A retrospective analysis was conducted on 272 patients whose ACL function was verified intraoperatively between October 2021 and October 2024. The patients were categorized into ACL-functional and ACL-dysfunctional groups. Using least absolute shrinkage and selection operator regression and logistic regression, four significant radiographic predictors were identified: location of the deepest wear on the medial tibial plateau (middle and posterior), wear depth in the posterior third of the medial tibial plateau (> 1.40 mm), posterior tibial slope (PTS > 7.90°), and static anterior tibial translation (> 4.49 mm). A clinical prediction model was developed and visualized using a nomogram with calibration curves and receiver operating characteristic analysis to confirm the model performance. The prediction model demonstrated great discriminative ability, showing area under the curve values of 0.831 (88.4% sensitivity, 63.8% specificity) and 0.907 (86.1% sensitivity, 82.2% specificity) in the training and validation cohorts, respectively. Consequently, the authors established an efficient approach for accurate evaluation of ACL function in KOA patients.</p>","PeriodicalId":29931,"journal":{"name":"Visual Computing for Industry Biomedicine and Art","volume":"8 1","pages":"14"},"PeriodicalIF":3.2,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12143998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Visual Computing for Industry Biomedicine and Art
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1