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Effect of 12 Weeks of Intensive Interval and Combined Training on Apolipoprotein A and B, Visfatin and Insulin Resistance in Overweight Middle-Aged Women with Type 2 Diabetes 12周间歇强化联合训练对超重中年2型糖尿病女性载脂蛋白A、B、内脂素和胰岛素抵抗的影响
Pub Date : 2016-06-10 DOI: 10.18869/ACADPUB.HMS.22.3.237
معصومه حسینیان, ابراهیم بنی طالبی, سیداحسان امیرحسینی
Aims: Probabely through improvements in the levels of apolipoproteins (ApoA and ApoB) and visfatin, the sport activities helps to reduce the risks of cardiovascular diseases in the diabetic persons. The aim of this study was to compare the effects of intensive interval and combined trainings on the levels of ApoA and ApoB, visfatin, and insulin resistance in the middle-aged women with Type II diabetes. Materials & Methods: In the semi-experimental study, 52 middle-aged female patients with Type II diabetes were studied in Shahr-e-Kord in 2015. The subjects, selected by convenience sampling method, were randomly divided into three groups, incluing simultaneous strength-endurance training, interval intensive training, and control groups. 12-week trainings, composed of three endurance training sessions per week with 60% of maximum heart rate and two resistance training sessions per week with 70% of one maximum repetition, were done in strength-endurance group. Three training sessions per week with 4-10 repetition of 30-second Wingate test on the ergometer were conducted in interval intensive training group with maximum effort. Data was analyzed by SPSS 21 software using dependent T test, covariance analysis, and LSD test. Findings: At the post-test stage and following interval intensive trainings, ApoA reduction (p=0.03) and ApoB/ApoA (p=0.01) were significant. However, no significant difference was observed in combined group. The levels of visfatin and serum insulin and insulin resistance index significantly decreased in both training groups (p<0.01). Conclusion: The interval intensive trainings further affect the levels of blood apolipoprotein, visfatin, and insulin resistance in the middle-aged women with Type II diabetes, than the combined endurance-resistance trainings.
目的:运动可能通过改善载脂蛋白(ApoA和ApoB)和脂肪素水平,有助于降低糖尿病患者心血管疾病的风险。本研究的目的是比较高强度间歇训练和联合训练对中年2型糖尿病女性ApoA和ApoB水平、visfatin和胰岛素抵抗的影响。材料与方法:在半实验研究中,选取2015年Shahr-e-Kord的52例中年女性II型糖尿病患者为研究对象。采用方便抽样法,将被试随机分为同时力量耐力训练组、间歇强化训练组和对照组。力量-耐力组进行为期12周的训练,包括每周3次耐力训练,最大心率为60%,每周2次阻力训练,最大重复次数为70%。间歇强化训练组每周进行3次训练,每次进行4-10次30秒温盖特测力仪测试。数据采用SPSS 21软件进行相关T检验、协方差分析和LSD检验。结果:在测试后阶段和间歇强化训练后,ApoA降低(p=0.03)和ApoB/ApoA (p=0.01)具有显著性。而联合组无明显差异。两组大鼠内脏脂肪素水平、血清胰岛素和胰岛素抵抗指数均显著降低(p<0.01)。结论:间歇强化训练比耐力-阻力联合训练更能影响中年2型糖尿病女性血载脂蛋白、脂肪素和胰岛素抵抗水平。
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引用次数: 3
Protective Effect of Hydroalcoholic Extract of Salvia officinalis L. against Acute Liver Toxicity of Acetaminophen in Mice 鼠尾草水醇提取物对对乙酰氨基酚急性肝毒性的保护作用
Pub Date : 2016-06-10 DOI: 10.18869/ACADPUB.HMS.22.3.185
Hossein Foruozandeh, M. V. Niri, M. Kalantar, M. Azadi, M. Samadani
Article Type Original Research Authors Foruozandeh H.* PhD, Vosughi Niri M.1 PhD, Kalantar M.1 PhD, Azadi M.1 MSc, Samadani M.1 MD How to cite this article Foruozandeh H, Vosughi Niri M, Kalantar M, Azadi M, Samadani M. Protective Effect of Hydroalcoholic Extract of Salviaofficinalis L.against Acute Liver Toxicity of Acetaminophen in Mice. Quarterly of the Horizon of Medical Sciences. 2016;22(3):185-191. Copyright© 2016 ASP Ins. This open-access article is published under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits Share (copy and redistribute the material in any medium or format) and Adapt (remix, transform, and build upon the material) under the Attribution-NonCommercial terms.
文章类型原始研究作者Foruozandeh .* PhD, Vosughi Niri M.1 PhD, Kalantar M.1 PhD, Azadi M.1 MSc, Samadani M.1 MD本文引用方式Foruozandeh, Vosughi Niri M, Kalantar M, Azadi M, Samadani M.丹参水醇提取物对对乙酰氨基酚急性肝毒性的保护作用医学学刊,2016;22(3):185-191。版权所有©2016 ASP Ins。这篇开放获取的文章是在知识共享署名-非商业4.0国际许可证的条款下发布的,该许可证允许在署名-非商业条款下共享(以任何媒介或格式复制和再分发材料)和改编(重新混合,转换和构建材料)。
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引用次数: 3
Effect of Doll Injection Display on Pain Intensity due to Intramuscular Injection in Preschool Children 娃娃注射展示对学龄前儿童肌内注射疼痛强度的影响
Pub Date : 2016-06-10 DOI: 10.18869/ACADPUB.HMS.22.3.247
H. Irani, M. Eshghizadeh, M. Zivari
Aims: Pains caused by the invasive actions such as intramuscular injection lead to the physical and mental tensions in the children. Therefore, such pains should be given relief. One of the main priorities in the nursing is to notice methods that reduce pains due to the invasive actions in the children. The aim of this study was to investigate the effects of injection displayed on a doll on the pain intensity due to the intramuscular injection in the preschool children. Materials & Methods: In the randomized controlled clinical trial, 62 kids aged between 4 and 6 years with pharyngitis were studied in the clinic of the health network of Khalil-abad Township in 2015. The intramuscular injection of penicillin 6.3.3 was administrated for the kids. The subjects, selected by simple lottery, were divided into two groups including experimental and control groups (n=31 per group). Data was collected using a demographic characteristic collecting form and Oucher standard pain assessment tool. In experimental group, the kid watching, one intramuscular injection was displayed on a doll by a nurse; then, the kid underwent an intramuscular injection. In control group, the routine injection method was done. Data was analyzed by SPSS 19 software using Mann-Whitney, independent T, and Chisquare tests. Findings: Mean pain intensity after injection in experimental group (3.22±0.90) was significantly lower than control group (4.19±0.83; p<0.001). Conclusion: The injection displayed on a doll before the intramuscular injection might lead to pain reduction in the preschool kids.
目的:由于肌内注射等侵入性动作引起的疼痛导致儿童身心紧张。因此,这种痛苦应该得到缓解。护理中的一个主要优先事项是注意减少因儿童侵入性行为而引起的疼痛的方法。本研究的目的是探讨在玩偶上显示注射对学龄前儿童肌肉注射引起的疼痛强度的影响。材料与方法:采用随机对照临床试验,选取2015年在哈利勒阿巴德乡卫生网门诊就诊的62例4 ~ 6岁咽炎患儿为研究对象。患儿给予青霉素6.3.3静脉注射。采用简单摇号法抽取受试者,分为实验组和对照组两组,每组31人。使用人口统计学特征收集表和欧彻标准疼痛评估工具收集数据。在实验组,孩子观看,一个肌肉注射由护士展示在娃娃上;然后,孩子接受了肌肉注射。对照组采用常规注射方法。数据分析采用SPSS 19软件,采用Mann-Whitney检验、独立T检验和Chisquare检验。结果:实验组患者注射后平均疼痛强度(3.22±0.90)明显低于对照组(4.19±0.83);p < 0.001)。结论:学龄前儿童肌内注射前,在玩偶上展示注射剂可减轻疼痛。
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引用次数: 4
Comparison of Oral and Vaginal Prescription of Misoprostol in Labor Induction of Post-Term Pregnancies 米索前列醇口服与阴道处方在足月后引产中的比较
Pub Date : 2016-04-15 DOI: 10.18869/ACADPUB.HMS.22.2.103
معصومه رضایی, فریبا سیدالشهدایی, سوسن میرزا محمدی, فردین غریبی, مرتضی نایبی
Aims: There is a considerable increase in the maternal and infancy mortality and side-effects in accordance with higher pregnancy ages. Due to such a risk, it is nedded to statrt the labor induction from week 40. Misoprostol is one of the medications used in such conitions. The aim of this study was to compare the effects of oral misoprostol and vaginal misoprostol in the labor induction in the prolonged pregnancy. Materials & Methods: In the two-blinded random climical trial, 180 pregnant women with more than 40 weeks gestational age referred to the labor ward of Sanadaj Besat Hospital were studied in 2013-2014. The samples were selected via randomized blocking sampling method. Through sixtuple random blocking method, the subjects were divided into three groups including 50μg oral misoprostol, 100μg oral misoprostol, and 25μg vaginal misoprostol. Having been recorded on a checklist, data was analyzed by SPSS 18 software using oneway ANOVA, Chi-square, and Fisher’s exact tests. Findings: There were significant differences between the mean 1st minute Apgar score and the medication consumption dose in the groups (p=0.0001). There were no differences between the groups in the mean 5th minute Apgar score, induction frequency, induction times, mode of delivery, and its sideeffects (p>0.05). Nevertheless, there were significant differences in fetal distress frequency and the infant hospitalization (p<0.05). There were no significant differences in the mean interval between misoprostrol consumption and the delivery time between the groups (p=0.28). Conclusion: Considering the labor induction time and maternal and infancy outcomes, administration of 100μg oral misoprostrol in the prolonged pregnant women is more useful than 50μg oral misoprostrol and 25μg vaginal misoprostrol.
目的:随着怀孕年龄的增加,产妇和婴儿死亡率和副作用显著增加。由于存在这样的风险,需要从第40周开始引产。米索前列醇是在这种情况下使用的药物之一。本研究的目的是比较口服米索前列醇和阴道米索前列醇在延长妊娠引产中的效果。材料与方法:采用双盲随机临床试验,选取2013-2014年在Sanadaj Besat医院产房就诊的180例胎龄大于40周的孕妇为研究对象。采用随机分块抽样方法选取样本。通过六次随机阻断法,将受试者分为口服米索前列醇50μg、口服米索前列醇100μg、阴道米索前列醇25μg三组。在检查表上记录数据后,使用SPSS 18软件使用单因素方差分析、卡方检验和Fisher精确检验对数据进行分析。结果:两组患者平均1分钟Apgar评分及用药剂量差异有统计学意义(p=0.0001)。两组患者平均5分钟Apgar评分、引产次数、引产次数、分娩方式及不良反应比较,差异均无统计学意义(p>0.05)。然而,两组胎儿窘迫频率和婴儿住院率差异有统计学意义(p<0.05)。两组患者服用米索前列醇的平均间隔时间和分娩时间差异无统计学意义(p=0.28)。结论:考虑到引产时间和母婴结局,延长妊娠期妇女口服米索前列醇100μg比口服米索前列醇50μg和阴道米索前列醇25μg更有效。
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引用次数: 2
Effect of Ethanolic Extract of Propolis on Serum Biochemical Factors Level and Total Antioxidant Capacity in Adult Male Rats 蜂胶醇提物对成年雄性大鼠血清生化因子水平及总抗氧化能力的影响
Pub Date : 2016-04-15 DOI: 10.18869/ACADPUB.HMS.22.2.145
N. Gheybi, R. Bakhshibiniaz, R. Taherkhani, H. Hashemi, R. Chegini, M. Saremi, H. A. Zarmehri, Reza Nagafipour, M. Soufiabadi
Aims: Propolis is one of the natural materials collected by the honeybees. The material is extensively used to treat some diseases. The aim of this study was to determine the effects of ethanol extract of propolis of Qazvin plain on some biochemical factors, as well as serum antioxidant capacity, in adult male Wistar rats. Materials & Methods: In the experimental study, 40 adult male Wistar rats were divided into four groups (n=10 per group). The first was control group. The experimental groups received 50, 100, and 200mg/kg propolis. After 10day gavage, the serum of the rats being extracted, glucose, triglyceride, aspartate aminotransferase, alanine aminotransferase, and total antioxidant capacity were measured. Data was analyzed by SPSS 20 software using one-way ANOVA and Tykey’s post-hoc tests. Findings: There was no significant difference in the blood sugar level between different groups and control group. There was a significant reduction in triglyceride level in “100mg/kg” group than control group (p<0.001). There was a significant increase in aspartate aminotransferase level in “100mg/kg” (p<0.01) and “200mg/kg” (p<0.001) groups. There was a significant reduction in alanine aminotransferase level in “50mg/kg” group (p<0.001). Propolis led to a significant increase in the total antioxidant capacity of serum, especially at 50mg/kg (p<0.05) and 100mg/kg (p<0.01) doses. Conclusion: Oral consumption of propolis has a moderating effect on some blood biochemical factors especially triglyceride. In addition, it increases serum total antioxidant capacity. Nevertheless, its excessive consumption might damage patients with liver diseases.
目的:蜂胶是蜜蜂采集的天然原料之一。这种材料被广泛用于治疗某些疾病。本研究旨在探讨加士温平原蜂胶乙醇提取物对成年雄性Wistar大鼠部分生化指标及血清抗氧化能力的影响。材料与方法:实验研究选用成年雄性Wistar大鼠40只,分为4组,每组10只。第一组是对照组。试验组分别给予50、100、200mg/kg蜂胶。灌胃10d后,提取大鼠血清,测定葡萄糖、甘油三酯、天冬氨酸转氨酶、丙氨酸转氨酶及总抗氧化能力。数据采用SPSS 20软件进行单因素方差分析和Tykey事后检验。结果:各组患者血糖水平与对照组无显著差异。“100mg/kg”组甘油三酯水平显著低于对照组(p<0.001)。“100mg/kg”组和“200mg/kg”组的天冬氨酸转氨酶水平显著升高(p<0.01)。50mg/kg组丙氨酸转氨酶水平显著降低(p<0.001)。蜂胶显著提高了血清的总抗氧化能力,特别是在50mg/kg (p<0.05)和100mg/kg (p<0.01)剂量组。结论:口服蜂胶对血液生化指标有调节作用,尤其是对甘油三酯有调节作用。此外,它还能提高血清的总抗氧化能力。然而,过量食用可能会损害肝脏疾病患者。
{"title":"Effect of Ethanolic Extract of Propolis on Serum Biochemical Factors Level and Total Antioxidant Capacity in Adult Male Rats","authors":"N. Gheybi, R. Bakhshibiniaz, R. Taherkhani, H. Hashemi, R. Chegini, M. Saremi, H. A. Zarmehri, Reza Nagafipour, M. Soufiabadi","doi":"10.18869/ACADPUB.HMS.22.2.145","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.22.2.145","url":null,"abstract":"Aims: Propolis is one of the natural materials collected by the honeybees. The material is extensively used to treat some diseases. The aim of this study was to determine the effects of ethanol extract of propolis of Qazvin plain on some biochemical factors, as well as serum antioxidant capacity, in adult male Wistar rats. Materials & Methods: In the experimental study, 40 adult male Wistar rats were divided into four groups (n=10 per group). The first was control group. The experimental groups received 50, 100, and 200mg/kg propolis. After 10day gavage, the serum of the rats being extracted, glucose, triglyceride, aspartate aminotransferase, alanine aminotransferase, and total antioxidant capacity were measured. Data was analyzed by SPSS 20 software using one-way ANOVA and Tykey’s post-hoc tests. Findings: There was no significant difference in the blood sugar level between different groups and control group. There was a significant reduction in triglyceride level in “100mg/kg” group than control group (p<0.001). There was a significant increase in aspartate aminotransferase level in “100mg/kg” (p<0.01) and “200mg/kg” (p<0.001) groups. There was a significant reduction in alanine aminotransferase level in “50mg/kg” group (p<0.001). Propolis led to a significant increase in the total antioxidant capacity of serum, especially at 50mg/kg (p<0.05) and 100mg/kg (p<0.01) doses. Conclusion: Oral consumption of propolis has a moderating effect on some blood biochemical factors especially triglyceride. In addition, it increases serum total antioxidant capacity. Nevertheless, its excessive consumption might damage patients with liver diseases.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117216822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
8 Weeks of Resistance Training Effect on Myostatin Gene Expression of Myocardium in Healthy Male Wistar Rats 8周阻力训练对健康雄性Wistar大鼠心肌肌肉生长抑制素基因表达的影响
Pub Date : 2016-04-15 DOI: 10.18869/ACADPUB.HMS.22.2.111
امیر رشیدلمیر, محمد رضا باسامی, سیدرضا عطارزاده حسینی, کیوان حجازی, سیدمحمد متولی عنبرانی
Aims: Based on the clinical studies, there are higher myostatin gene expression and serum level in cardiovascular patients than the healthy persons. In addition, based on some studies, regular resistance exercises is in line with a reduction in the myostatin gene expression. The aim of this study was to investigate the effects of 8-week resistance exercises on the myostatin gene expressions of myocardium in the healthy male Wistar rats. Materials & Methods: In the experimental study, 13 male adult Wistar rats, aged 15 weeks, were divided into experimental (n=7) and control (n=6) groups. In experimental group, 8-week exercises were done as climbing up a 26-step 1meter ladder, inclined 85°, with a sinker. (There were 3 sessions a week exercises; each session consisted of 3 sets of 5 repetitions.) 24 hours after the last exercise session and after 12-hour fasting, the rats being dissected, muscle tissue samples were prepared to assess mRNA levels. Data was analyzed in SPSS 16 software using independent T test. Findings: After 8-week resistance exercises, there was no significant difference in the myostatin mRNA expression level in the myocardium between experimental (1.56±0.44) and control (1.94±0.55) groups (p=0.197). Conclusion: 8-week resistance exercises leads to no significant change in the myostatin gene expression of myocardium in the healthy Wistar male rats.
目的:通过临床研究发现,心血管病患者肌肉生长抑制素基因表达及血清水平均高于健康人。此外,根据一些研究,定期的阻力运动与肌肉生长抑制素基因表达的减少是一致的。本研究旨在探讨8周阻力运动对健康雄性Wistar大鼠心肌肌肉生长抑制素基因表达的影响。材料与方法:选取15周龄雄性成年Wistar大鼠13只,随机分为实验组(n=7)和对照组(n=6)。实验组进行为期8周的训练,以爬26级1米的梯子,倾斜85°,用下沉器。(每周有3次练习;最后一次运动后24小时和禁食后12小时,解剖大鼠,准备肌肉组织样本以评估mRNA水平。数据分析采用SPSS 16软件,采用独立T检验。结果:8周阻力运动后,实验组(1.56±0.44)与对照组(1.94±0.55)心肌肌生长抑制素mRNA表达量差异无统计学意义(p=0.197)。结论:8周阻力运动对健康Wistar雄性大鼠心肌肌生长抑制素基因表达无显著影响。
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引用次数: 2
Comparison the Effects of Intravenous Hydrocortisone and Dexamethasone before Extubation on Laryngospasm, Cough and Stridor after General Anesthesia 拔管前静脉注射氢化可的松与地塞米松对全麻后喉痉挛、咳嗽、喘鸣的影响比较
Pub Date : 2016-04-15 DOI: 10.18869/ACADPUB.HMS.22.2.89
A. Hamzei, M. Mogadam, mahmod Yousef zadeh Ghoshani, masomeh Heidary karizaki
Aims After tracheal extubation, following the patient’ waking up from general anesthesia, respiratory physiological responses are with symptoms such as cough, laryngospasm, and stridor. Different medications are used to prevent these complications. The aim of this study was to compare the effects of intravenous hydrocortisone and dexamethasone on the respiratory side-effects before tracheal extubation. Materials & Methods In this two-blinded clinical trial, 108 patients candidate for orthopedic surgery, general surgery, and urology by general anesthesia hospitalized in Shahid Hashemi Nezhad and Bidaxt 15th Khordad hospitals were studied in Mashhad, Iran, in 2015. The subjects were selected via available sampling method. Randomized assignment was done by BBR. The first and the second groups received 100mg hydrocortisone and 8mg dexamethasone 30 minutes before tracheal extubation as one intravenous dosing, respectively. Individual information and clinical status were recorded based on the diagnoses by an anesthesiologist. Data was analyzed by SPSS 13 software using Chi-square, independent T, and Mann-Whitney tests. Findings There was no significant difference between dexamethasone and hydrocortisone groups in the frequencies of cough, laryngospasm, and stridor (p>0.05). There were significant differences between the mean weights of patients with laryngospasm (p=0.03), cough (p=0.002), and stridor (p=0.001) and the patients without such symptoms. There was no significant difference in gender between patients with stridor and laryngospasm and other patients without such symptoms (p>0.05), excluding patients with cough (p=0.003). Conclusion The effects of hydrocortisone and dexamethasone are similar on laryngospasm, cough, and stridor after tracheal extubation.
目的气管拔管后,患者全麻苏醒后,呼吸生理反应出现咳嗽、喉痉挛、喘鸣等症状。不同的药物被用来预防这些并发症。本研究的目的是比较气管拔管前静脉注射氢化可的松和地塞米松对呼吸系统副作用的影响。材料与方法本双盲临床试验选取2015年在伊朗马什哈德Shahid Hashemi Nezhad和Bidaxt第15 Khordad医院住院的108例全麻骨科、普外科和泌尿外科候诊患者为研究对象。采用现有的抽样方法选取研究对象。随机分配由BBR完成。第一组和第二组在拔管前30分钟分别给予氢化可的松100mg和地塞米松8mg,为单次静脉给药。根据麻醉医师的诊断记录患者的个人信息和临床状况。数据分析采用SPSS 13软件,采用卡方检验、独立T检验和Mann-Whitney检验。地塞米松组与氢化可的松组患者咳嗽、喉痉挛、喘鸣频次比较,差异无统计学意义(p>0.05)。有喉痉挛(p=0.03)、咳嗽(p=0.002)、喘鸣(p=0.001)患者的平均体重与无这些症状的患者有显著差异。除咳嗽患者外,有喘鸣、喉痉挛患者与无喘鸣、喉痉挛患者的性别差异无统计学意义(p>0.05)。结论氢化可的松与地塞米松对气管拔管后喉痉挛、咳嗽、喘鸣的作用相似。
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引用次数: 0
Comparison between Sedation-Agitation and Visual Analog Scales in Determination of Sedation Status of Patients 镇静-躁动与视觉模拟量表测定患者镇静状态的比较
Pub Date : 2016-04-15 DOI: 10.18869/ACADPUB.HMS.22.2.159
A. Alami, Zahra Moradi, A. D. Noghabi, A. Hamzei
Aims: To reduce discomfort and anxiety, providing true sedation for the patients hospitalized in ICU is very important. Therefore, the staff of ICU needs tools to measure effective sedation in the patients. The aim of this study was to assess the sedation status in the patients hospitalized in ICU via SedationAgitation Scale (SAS) and to compare the findings with Visual Analog Scale (VAS). Instrument & Methods: In this correlational study in 2015, 106 patients hospitalized in the intensive care units of Qaem Hospital of Mashhad, Iran, were selected via quota sampling method and studied. Sedation status of the patients was assessed by the validated Persian version of SAS and VAS. Data was analyzed by SPSS 20 software and Spearman’s correlation coefficient test. Findings: There was a positive and significant correlation between SAS and VAS (p<0.001; r=0.824). The highest scoring of SAS, which was 6, was equivalent to score 3 in VAS. In general, the higher the score of SAS, the higher the score of VAS was. Conclusion: SAS and VAS are in a high correlation to assess sedation. Therefore, SAS can be used as a valid tool in the treatment sector.
目的:为ICU住院患者提供真正意义上的镇静对减轻患者的不适和焦虑具有重要意义。因此,ICU的工作人员需要工具来测量患者的有效镇静。本研究的目的是通过镇静搅拌量表(SAS)评估ICU住院患者的镇静状态,并与视觉模拟量表(VAS)进行比较。工具与方法:本相关性研究采用配额抽样方法,选取2015年在伊朗马什哈德Qaem医院重症监护病房住院的106例患者进行研究。采用经验证的波斯版SAS和VAS评估患者的镇静状态。数据分析采用SPSS 20软件,Spearman相关系数检验。结果:SAS与VAS存在显著正相关(p<0.001;r = 0.824)。SAS评分最高为6分,与VAS评分3分相当。一般情况下,SAS评分越高,VAS评分越高。结论:SAS和VAS在评价镇静作用方面具有较高的相关性。因此,SAS可以作为治疗领域的有效工具。
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引用次数: 1
Effect of Mobile Radiation and Diabetes on Pituitary-Gonadal Axis Function in Adult Male Rats 运动辐射与糖尿病对成年雄性大鼠垂体-性腺轴功能的影响
Pub Date : 2016-04-15 DOI: 10.18869/ACADPUB.HMS.22.2.131
ابراهیم حسینی, زهرا قناعتیان
Aims: The potential risk of radiations caused by the mobile phones affecting human, as well as the prevalence of diabetes, are of the main concerns in developing and modern societies. The aim of this study was to investigate the effects of radiations caused by the mobile phones on the serum level of sexual hormones in streptozocin-induced diabetic adult male rats. Materials & Methods: In the experimental study, 64 Wistar adult male rats were studied. The rats were divided into 8 groups (n=8 per group) including non-diabetic control, diabetic control, and 6 experimental groups. Control groups received no treatment. Diabetic experimental groups underwent 7-day continuous and cutoff mobile radiations and buzzer sound. At the end of the course, blood sampling having been done, serum levels of LH, FSH, and testosterone were measured. Data was analyzed by SPPS 18 software using one-way ANOVA and Tukey’s post-hoc. Findings: Diabetes alone and with continuous and cutoff radiations of the mobile phones and buzzer sound led to a reduction in testosterone level (p<0.05). Diabetes had no effect on LH and FSH. Nevertheless, 2-hour cutoff radiations of the mobile phones led to a significant increase in FSH in the diabetic rats (p<0.005). In addition, 1-hour and 2-hour continuous radiations and 2-hour cutoff radiations of the mobile phones led to significant increases in LH in the diabetic rats (p<0.05). Conclusion: In adult male rats, diabetes, radiations of mobile phones and buzzer sound lead to testosterone reduction. In addition, diabetes with mobile phone radiations leads to increases in LH and FSH levels.
目的:手机对人类造成的潜在辐射风险,以及糖尿病的患病率,是发展中国家和现代社会关注的主要问题。本研究旨在探讨手机辐射对链脲佐菌素诱导的糖尿病成年雄性大鼠血清性激素水平的影响。材料与方法:以Wistar成年雄性大鼠64只为实验对象。将大鼠分为8组,每组n=8只,分别为非糖尿病对照组、糖尿病对照组和6个实验组。对照组不接受任何治疗。糖尿病试验组连续和切断移动辐射和蜂鸣器声音7 d。在课程结束时,进行了血液采样,测量了血清LH, FSH和睾酮水平。数据采用SPPS 18软件进行单因素方差分析和Tukey’s事后分析。结果:糖尿病患者与手机、蜂鸣器持续、切断辐射均可导致睾酮水平降低(p<0.05)。糖尿病对LH和FSH无影响。然而,2小时的手机切断辐射导致糖尿病大鼠FSH显著增加(p<0.005)。手机1小时、2小时连续辐射和2小时切断辐射导致糖尿病大鼠LH显著升高(p<0.05)。结论:糖尿病、手机辐射和蜂鸣器声音导致成年雄性大鼠睾酮水平降低。此外,手机辐射引起的糖尿病会导致黄体生成素和卵泡刺激素水平升高。
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引用次数: 0
Comparison of Brain CT Scan and without Contrast MRI Findings of Epileptic Children 癫痫儿童脑CT与非MRI对比分析
Pub Date : 2016-04-15 DOI: 10.18869/ACADPUB.HMS.22.2.165
R. Fallah, Helia Falahatian Mehrjardi, R. N. Moghadam, M. Sepehri
Aims: Epilepsy is one of the most common children diseases, and MRI is a method to understand its etiology. Since there was no MRI in many medical centers, the aim of this study was to compare the findings of CT scan and MRI without contrast in epileptic children. Instrument & Methods: In this descriptive-analytic study, 1-month to 14-year old epileptic children (n=160) referred to Pediatric Neurology Clinic of Yazd Shahid Sadoughi Medical University were studied in September 2012. Data was recorded in a questionnaire via interviews with the parents, biography, physical exams, and investigating the findings of CT scan and MRI. Data was analyzed in SPSS 15 software using Chi-square test. Findings: There were normal and abnormal CT scans in 121 (75.6%) and 39 (24.4%) children, respectively. There were normal and abnormal MRI findings in 84 (52.5%) and 76 (47.5%) children, respectively. The results of CT scan and MRI were consistent in 119 (73.4%) children (p=0.001). There were more prevalent abnormal CT scans in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography. There were more prevalent abnormal MRI cases in 214 years children, developmental delayed children, abnormal physical exam, focal seizure, and non-specific abnormal electroencephalography. Conclusion: To investigate 2-14 years old epileptic children, focal seizure, and non-specific abnormal electroencephalography, MRI is preferable than CT scan. The latter is useful in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography.
目的:癫痫是儿童最常见的疾病之一,MRI是了解其病因的一种手段。由于许多医疗中心没有核磁共振成像,本研究的目的是比较癫痫儿童CT扫描和核磁共振成像的结果。工具与方法:本描述性分析研究于2012年9月在Yazd Shahid Sadoughi医科大学儿科神经内科就诊的1个月至14岁癫痫儿童(n=160)进行研究。数据通过父母访谈、传记、体格检查、CT扫描和MRI调查结果等方式记录在问卷中。数据分析采用SPSS 15软件,采用卡方检验。结果:CT扫描正常121例(75.6%),异常39例(24.4%)。MRI表现正常84例(52.5%),异常76例(47.5%)。119例(73.4%)患儿CT与MRI检查结果一致(p=0.001)。CT异常多见于6个月以下儿童、发育迟缓儿童、体格检查异常及癫痫性脑电图异常。214岁儿童MRI异常、发育迟缓儿童、体格检查异常、局灶性发作和非特异性脑电图异常更为普遍。结论:对2 ~ 14岁儿童癫痫、局灶性发作和非特异性脑电图异常的诊断,MRI优于CT。后者适用于6个月以下儿童、发育迟缓儿童、体检异常和癫痫性脑电图异常。
{"title":"Comparison of Brain CT Scan and without Contrast MRI Findings of Epileptic Children","authors":"R. Fallah, Helia Falahatian Mehrjardi, R. N. Moghadam, M. Sepehri","doi":"10.18869/ACADPUB.HMS.22.2.165","DOIUrl":"https://doi.org/10.18869/ACADPUB.HMS.22.2.165","url":null,"abstract":"Aims: Epilepsy is one of the most common children diseases, and MRI is a method to understand its etiology. Since there was no MRI in many medical centers, the aim of this study was to compare the findings of CT scan and MRI without contrast in epileptic children. Instrument & Methods: In this descriptive-analytic study, 1-month to 14-year old epileptic children (n=160) referred to Pediatric Neurology Clinic of Yazd Shahid Sadoughi Medical University were studied in September 2012. Data was recorded in a questionnaire via interviews with the parents, biography, physical exams, and investigating the findings of CT scan and MRI. Data was analyzed in SPSS 15 software using Chi-square test. Findings: There were normal and abnormal CT scans in 121 (75.6%) and 39 (24.4%) children, respectively. There were normal and abnormal MRI findings in 84 (52.5%) and 76 (47.5%) children, respectively. The results of CT scan and MRI were consistent in 119 (73.4%) children (p=0.001). There were more prevalent abnormal CT scans in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography. There were more prevalent abnormal MRI cases in 214 years children, developmental delayed children, abnormal physical exam, focal seizure, and non-specific abnormal electroencephalography. Conclusion: To investigate 2-14 years old epileptic children, focal seizure, and non-specific abnormal electroencephalography, MRI is preferable than CT scan. The latter is useful in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography.","PeriodicalId":300087,"journal":{"name":"The Horizon of Medical Sciences","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125051050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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The Horizon of Medical Sciences
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