Abstract Objective To evaluate mass screening campaigns for tuberculosis in prisoners in Ecuador. Material and method Cross-sectional study of Chronic Cough (CC) detected amongst inmates who entered two prisons in Ecuador between January and December 2016 (n = 12,365). The time distribution of the CCs was analyzed with the uniformity test and its relationship with the diagnosed cases of PTB, the prevalence of PTB was calculated. A logistic regression model was performed to determine the factors modifiers of PTB positivity. Results 1.332 chronic cougher were recorded, the positivity rate was 17.3% (95% CI, 15.1-19.4), and the prevalence was 1.9% (95% CI, 1.6 - 2.1). There was an absence of uniformity in the detection and diagnosis by epidemiological weeks; there was a positive correlation between CC and PTB cases. The positivity rate was associated with the prison with the highest density (adjusted OR 3.8; 95% CI, 2.5-5.5). Discussion Massive screening campaigns are not enough to control tuberculosis in Ecuador’s prisons. The incidence found is high. It is necessary to strengthen the diagnostic process to treat all the cases found and thus break the chain of transmission.
{"title":"Is mass screening enough to control tuberculosis in Ecuador’s prisons?","authors":"I. Valcárcel-Pérez, J. Molina, Z. Fuentes","doi":"10.18176/resp.00038","DOIUrl":"https://doi.org/10.18176/resp.00038","url":null,"abstract":"Abstract Objective To evaluate mass screening campaigns for tuberculosis in prisoners in Ecuador. Material and method Cross-sectional study of Chronic Cough (CC) detected amongst inmates who entered two prisons in Ecuador between January and December 2016 (n = 12,365). The time distribution of the CCs was analyzed with the uniformity test and its relationship with the diagnosed cases of PTB, the prevalence of PTB was calculated. A logistic regression model was performed to determine the factors modifiers of PTB positivity. Results 1.332 chronic cougher were recorded, the positivity rate was 17.3% (95% CI, 15.1-19.4), and the prevalence was 1.9% (95% CI, 1.6 - 2.1). There was an absence of uniformity in the detection and diagnosis by epidemiological weeks; there was a positive correlation between CC and PTB cases. The positivity rate was associated with the prison with the highest density (adjusted OR 3.8; 95% CI, 2.5-5.5). Discussion Massive screening campaigns are not enough to control tuberculosis in Ecuador’s prisons. The incidence found is high. It is necessary to strengthen the diagnostic process to treat all the cases found and thus break the chain of transmission.","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"23 1","pages":"108 - 114"},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49447379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Objective To analyze the different perceptions of professionals about the problem of intellectual disability in the prison setting. Material and method Exploratory-descriptive type. In-depth interviews with legal, social and prison operators of Centro Penitenciario de Zuera (Zaragoza). Results The narratives of the interviewed subjects point to the aggravating circumstances that a closed social environment can entail for inmates with intellectual disabilities. Communications in the prison administration are written in a technical language that is not understandable for inmates with intellectual deficits. Discusion There is a need to give more visibility to the case of inmates with intellectual disabilities. Procedures also need to be applied that favour greater cognitive accessibility for this profile of inmates, along with the promotion of awareness raising and training for professionals to enable them to deal with this issue.
{"title":"Analysis of penitentiary, social and legal operators’ perceptions of prison inmates with intellectual disabilities","authors":"J. García-Martínez, C. Álvarez","doi":"10.18176/resp.00040","DOIUrl":"https://doi.org/10.18176/resp.00040","url":null,"abstract":"Abstract Objective To analyze the different perceptions of professionals about the problem of intellectual disability in the prison setting. Material and method Exploratory-descriptive type. In-depth interviews with legal, social and prison operators of Centro Penitenciario de Zuera (Zaragoza). Results The narratives of the interviewed subjects point to the aggravating circumstances that a closed social environment can entail for inmates with intellectual disabilities. Communications in the prison administration are written in a technical language that is not understandable for inmates with intellectual deficits. Discusion There is a need to give more visibility to the case of inmates with intellectual disabilities. Procedures also need to be applied that favour greater cognitive accessibility for this profile of inmates, along with the promotion of awareness raising and training for professionals to enable them to deal with this issue.","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"79 1","pages":"115 - 118"},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67718804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Hepatitis B is a parenterally and sexually transmitted infection. Vaccination for the disease is highly effective, and its inclusion in Spain as part of a systematic and universal schedule for newborns has led to a significant decrease of incidence in the national population. However, the number of inmates born in other countries some from endemic areas of HBV infection -, the mechanisms of transmission and lack of vaccination in third world countries mean that its prevalence in the prison population is higher than in the general population. These institutions therefore play an essential role in detecting and managing hepatitis B. In this paper, the situation of hepatitis B in prisons is reviewed and recommendations are proposed to optimize its control.
{"title":"Diagnosis and treatment of hepatitis B. What contributions can prisons make?","authors":"M. Vergara","doi":"10.18176/resp.00041","DOIUrl":"https://doi.org/10.18176/resp.00041","url":null,"abstract":"Abstract Hepatitis B is a parenterally and sexually transmitted infection. Vaccination for the disease is highly effective, and its inclusion in Spain as part of a systematic and universal schedule for newborns has led to a significant decrease of incidence in the national population. However, the number of inmates born in other countries some from endemic areas of HBV infection -, the mechanisms of transmission and lack of vaccination in third world countries mean that its prevalence in the prison population is higher than in the general population. These institutions therefore play an essential role in detecting and managing hepatitis B. In this paper, the situation of hepatitis B in prisons is reviewed and recommendations are proposed to optimize its control.","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"16 1","pages":"119 - 127"},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67718817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Maestro-González, M. Sánchez-Zaballos, M. Mosteiro-Díaz, D. Zuazua-Rico
Abstract Objective To analyze the reasons for seeking emergency medical care amongst prison inmates and their relationship to sociodemographic characteristics. Material and method An observational, descriptive and retrospective study was carried out. We collected the sociodemographic variables of inmates and their healthcare needs at the referral hospital over nine years. Results A total of 972 hospital visits were included. The most common healthcare needs, in descending order, were multiple trauma, limb problems and dyspnea. Mondays and Wednesdays were found to be the busiest days (P <0.001). The average stay in cases of hospitalization was 6.1 (SD: 4.3) days; patients with nontraumatic healthcare needs required a longer stay. The majority of the inmates native to Africa, Asia and America received emergency healthcare services due to traumatic injuries; by contrast the most common injuries among Europeans were non-traumatic and unrelated to suicide attempts (P <0.001). European inmates were on average 4.2 years older than Africans and 4.7 years older than American inmates (P <0.001). Discussion The reasons for seeking emergency care are clearly differentiated according to the inmates’ nationality, one notable outcome was the greater longevity of European internees. These results highlight the importance of understanding healthcare demand within the prison system in order to better address considerations such as prevention, organization and the location of healthcare units.
{"title":"Analysis of Emergency Healthcare Demand in a Prison","authors":"A. Maestro-González, M. Sánchez-Zaballos, M. Mosteiro-Díaz, D. Zuazua-Rico","doi":"10.18176/resp.00037","DOIUrl":"https://doi.org/10.18176/resp.00037","url":null,"abstract":"Abstract Objective To analyze the reasons for seeking emergency medical care amongst prison inmates and their relationship to sociodemographic characteristics. Material and method An observational, descriptive and retrospective study was carried out. We collected the sociodemographic variables of inmates and their healthcare needs at the referral hospital over nine years. Results A total of 972 hospital visits were included. The most common healthcare needs, in descending order, were multiple trauma, limb problems and dyspnea. Mondays and Wednesdays were found to be the busiest days (P <0.001). The average stay in cases of hospitalization was 6.1 (SD: 4.3) days; patients with nontraumatic healthcare needs required a longer stay. The majority of the inmates native to Africa, Asia and America received emergency healthcare services due to traumatic injuries; by contrast the most common injuries among Europeans were non-traumatic and unrelated to suicide attempts (P <0.001). European inmates were on average 4.2 years older than Africans and 4.7 years older than American inmates (P <0.001). Discussion The reasons for seeking emergency care are clearly differentiated according to the inmates’ nationality, one notable outcome was the greater longevity of European internees. These results highlight the importance of understanding healthcare demand within the prison system in order to better address considerations such as prevention, organization and the location of healthcare units.","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"8 1","pages":"91 - 97"},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67718789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
88 Current estimates give figures of approximately 240 million people with chronic hepatitis B virus infection (HBV). The distribution of the disease is very heterogeneous, with a more marked prevalence (high prevalence = ≥8% of the population) in countries in Africa and South East Asia1. HBV infection is responsible for most cases of cirrhosis and liver cancer worldwide, which have a considerable impact on healthcare resources. In Spain, despite the prevention campaigns implemented through health education and screening of pregnant women and high risk groups, and the establishment of universal vaccination in the nineties2, current prevalence is estimated curren prevalence is estimated to be at around 0.2-1.7%, making Spain a country with low endemicity (<2% of the population with infection)3. This prevalence has increased in recent years, probably as a result of migratory movements of persons who have not been vaccinated against hepatitis B or who come from countries with high levels of endemicity. Improved notification of cases may also be another factor4. A recent study on adults who went to the Emergency Department of a university hospital in Catalonia with symptoms compatible with acute hepatitis showed that HBV infection was the main aetiological cause5. One third of cases were immigrants from countries with no vaccination programmes, and sexual transmission was found to be the main associated risk factor. The fact that chronic hepatitis B is an asymptomatic infection up to the advanced stages of liver disease, implies that many persons are unaware of being infected. There are also cases of patients who know that they are infected and do not receive adequate monitoring. The WHO estimates that less than 5% of the individuals infected with HBV in low-income countries are aware of the diagnosis6. Therefore, screening and linkage to care programs for patients with hepatitis B, especially in certain high risk groups, would help to prevent the disease from progressing, which in turn would have a highly positive impact on public health. The possibility of preventing further progression of liver disease and the resulting complications led to the WHO approving the 2016 Global Health Sector Strategy to eliminate hepatitis B and C by 20307. The program includes a wide range of strategies, many of which are focused on prisons. As Vergara M8, comments in her study, prisons represent an opportunity for screening, treatment and monitoring of a number of pathologies, and for discovering more about their natural history, since they include groups where the prevalence of diseases associated with certain risk factors is greater than in the community. This scenario is well known in the case of hepatitis C, where several strategies of microelimination in prisons have been put into effect in a number of Spanish prisons with excellent results and highly valued experience9. There is a large amount of data to support the benefits of such programs in terms of diagno
{"title":"Prisons: an important link in the elimination of Hepatitis B","authors":"A. Barreira-Díaz, M. Buti","doi":"10.18176/resp.00036","DOIUrl":"https://doi.org/10.18176/resp.00036","url":null,"abstract":"88 Current estimates give figures of approximately 240 million people with chronic hepatitis B virus infection (HBV). The distribution of the disease is very heterogeneous, with a more marked prevalence (high prevalence = ≥8% of the population) in countries in Africa and South East Asia1. HBV infection is responsible for most cases of cirrhosis and liver cancer worldwide, which have a considerable impact on healthcare resources. In Spain, despite the prevention campaigns implemented through health education and screening of pregnant women and high risk groups, and the establishment of universal vaccination in the nineties2, current prevalence is estimated curren prevalence is estimated to be at around 0.2-1.7%, making Spain a country with low endemicity (<2% of the population with infection)3. This prevalence has increased in recent years, probably as a result of migratory movements of persons who have not been vaccinated against hepatitis B or who come from countries with high levels of endemicity. Improved notification of cases may also be another factor4. A recent study on adults who went to the Emergency Department of a university hospital in Catalonia with symptoms compatible with acute hepatitis showed that HBV infection was the main aetiological cause5. One third of cases were immigrants from countries with no vaccination programmes, and sexual transmission was found to be the main associated risk factor. The fact that chronic hepatitis B is an asymptomatic infection up to the advanced stages of liver disease, implies that many persons are unaware of being infected. There are also cases of patients who know that they are infected and do not receive adequate monitoring. The WHO estimates that less than 5% of the individuals infected with HBV in low-income countries are aware of the diagnosis6. Therefore, screening and linkage to care programs for patients with hepatitis B, especially in certain high risk groups, would help to prevent the disease from progressing, which in turn would have a highly positive impact on public health. The possibility of preventing further progression of liver disease and the resulting complications led to the WHO approving the 2016 Global Health Sector Strategy to eliminate hepatitis B and C by 20307. The program includes a wide range of strategies, many of which are focused on prisons. As Vergara M8, comments in her study, prisons represent an opportunity for screening, treatment and monitoring of a number of pathologies, and for discovering more about their natural history, since they include groups where the prevalence of diseases associated with certain risk factors is greater than in the community. This scenario is well known in the case of hepatitis C, where several strategies of microelimination in prisons have been put into effect in a number of Spanish prisons with excellent results and highly valued experience9. There is a large amount of data to support the benefits of such programs in terms of diagno","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"23 1","pages":"88 - 90"},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67718773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study explores the experiences of incarcerated women living with their children in the Women Chorrillos Penitentiary, Lima, Peru, 2020.
Material and method: Qualitative, exploratory study with a phenomenological design, through semi-structured interviews with inmates who lived with their minor in the prison. In total there were 13 interviews considering the theoretical saturation of categories.
Results: The experiences consisted of mostly negative intrapersonal experiences, related to different individual aspects and the conditions of confinement and prison treatment. Serious deficiencies perceived in the health care of inmates and children stand out, with emphasis on mistreatment and indifference on the part of the staff. Other factors involved in the construction of these experiences were identified.
Discussion: The results provide evidence of serious structural and organizational deficiencies that violate the fundamental rights of the population group studied. Government efforts to date are partial and insufficient. Sustainable policies and programs are urgently needed that prioritize quality health care and adequate prison treatment for these people with an emphasis on preventive promotional actions. There is a need for evidence-based interventions to reduce the harmful effects of childhood incarceration.
{"title":"Experiences of incarcerated mothers living with their children in a prison in Lima, Peru, 2020: a qualitative study.","authors":"B M Martínez-Álvarez, A Sindeev","doi":"10.18176/resp.00039","DOIUrl":"10.18176/resp.00039","url":null,"abstract":"<p><strong>Objectives: </strong>This study explores the experiences of incarcerated women living with their children in the Women Chorrillos Penitentiary, Lima, Peru, 2020.</p><p><strong>Material and method: </strong>Qualitative, exploratory study with a phenomenological design, through semi-structured interviews with inmates who lived with their minor in the prison. In total there were 13 interviews considering the theoretical saturation of categories.</p><p><strong>Results: </strong>The experiences consisted of mostly negative intrapersonal experiences, related to different individual aspects and the conditions of confinement and prison treatment. Serious deficiencies perceived in the health care of inmates and children stand out, with emphasis on mistreatment and indifference on the part of the staff. Other factors involved in the construction of these experiences were identified.</p><p><strong>Discussion: </strong>The results provide evidence of serious structural and organizational deficiencies that violate the fundamental rights of the population group studied. Government efforts to date are partial and insufficient. Sustainable policies and programs are urgently needed that prioritize quality health care and adequate prison treatment for these people with an emphasis on preventive promotional actions. There is a need for evidence-based interventions to reduce the harmful effects of childhood incarceration.</p>","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"23 3","pages":"98-107"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/87/2013-6463-sanipe-23-03-98.PMC8802819.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10319181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Vargas-Herrera, S Roque de la Piedra, C Padilla-Rojas, M Yagui-Moscoso
{"title":"Identification of the Gamma variant in an outbreak of COVID-19 at a prison in Peru.","authors":"N Vargas-Herrera, S Roque de la Piedra, C Padilla-Rojas, M Yagui-Moscoso","doi":"10.18176/resp.00042","DOIUrl":"10.18176/resp.00042","url":null,"abstract":"","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"23 1","pages":"128-129"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67718837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomedical research in Spanish prisons: a reality full of difficulties.","authors":"Enrique Vera","doi":"10.18176/resp.00030","DOIUrl":"https://doi.org/10.18176/resp.00030","url":null,"abstract":"","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"23 2","pages":"46-48"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/90/15/2013-6463-sanipe-23-02-46.PMC8592263.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39198714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P A Martínez-Carpio, M Álvarez, R Fortea, A Bedoya Del Campillo
{"title":"Self harm: suturing of lips.","authors":"P A Martínez-Carpio, M Álvarez, R Fortea, A Bedoya Del Campillo","doi":"10.18176/resp.00035","DOIUrl":"10.18176/resp.00035","url":null,"abstract":"","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"23 2","pages":"86-87"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6a/69/2013-6463-sanipe-23-02-86.PMC8592265.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39198720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The efficacy of new direct-acting antivirals (DAAs) in treating hepatitis C infection can depend on treatment adherence, which may be influenced by the patient's current lack of awareness of the disease. This study set out to understand the treatment naïve chronic hepatitis C patients' preferences for new DAAs (attributes) and to compile information about the diagnosis process.
Material and method: Spanish quantitative market research study conducted between November 2018 and January 2019 to assess the posology preferences of treatment-naïve patients with chronic hepatitis C before starting treatment (seen by hepatologists and infectious diseases specialists). A telephone interview was carried out to collect demographic, diagnostic and treatment preference data, consisting of two dosing OPTIONS: 1) three tablets/day (single dose), at the same time, with food (8 weeks). 2) single tablet/day, at any time with/without food (12 weeks). A descriptive analysis of pooled results was performed.
Results: 104 patients (mean age: 49 years) with hepatitis C diagnosed 7.3±9.7 years ago (average), mainly in primary care (PC) (42%). The most common reasons for not having started treatment were health problems/comorbidities (31%). Fifty-eight percent of patients were not informed about the available treatments. Seventy-two percent of patients preferred a simple tablet/day, at any time, with/without food (12 weeks), and considered compatibility with other treatments, side effects, ease of administration, treatment duration and the number of tablets to be very important.
Discussion: Patient preferences are mainly driven by dosing flexibility and simplicity, including freedom to take the medication with/without food. The role of PC in the diagnosis should be taken into account. There are still patients who are untreated after diagnosis.
{"title":"Patients' preferences for treatment with the new direct acting antiviral therapies for chronic hepatitis C virus infection.","authors":"M A Simón, O Rojo, P Ryan","doi":"10.18176/resp.00033","DOIUrl":"https://doi.org/10.18176/resp.00033","url":null,"abstract":"<p><strong>Objectives: </strong>The efficacy of new direct-acting antivirals (DAAs) in treating hepatitis C infection can depend on treatment adherence, which may be influenced by the patient's current lack of awareness of the disease. This study set out to understand the treatment naïve chronic hepatitis C patients' preferences for new DAAs (attributes) and to compile information about the diagnosis process.</p><p><strong>Material and method: </strong>Spanish quantitative market research study conducted between November 2018 and January 2019 to assess the posology preferences of treatment-naïve patients with chronic hepatitis C before starting treatment (seen by hepatologists and infectious diseases specialists). A telephone interview was carried out to collect demographic, diagnostic and treatment preference data, consisting of two dosing OPTIONS: 1) three tablets/day (single dose), at the same time, with food (8 weeks). 2) single tablet/day, at any time with/without food (12 weeks). A descriptive analysis of pooled results was performed.</p><p><strong>Results: </strong>104 patients (mean age: 49 years) with hepatitis C diagnosed 7.3±9.7 years ago (average), mainly in primary care (PC) (42%). The most common reasons for not having started treatment were health problems/comorbidities (31%). Fifty-eight percent of patients were not informed about the available treatments. Seventy-two percent of patients preferred a simple tablet/day, at any time, with/without food (12 weeks), and considered compatibility with other treatments, side effects, ease of administration, treatment duration and the number of tablets to be very important.</p><p><strong>Discussion: </strong>Patient preferences are mainly driven by dosing flexibility and simplicity, including freedom to take the medication with/without food. The role of PC in the diagnosis should be taken into account. There are still patients who are untreated after diagnosis.</p>","PeriodicalId":30044,"journal":{"name":"Revista Espanola de Sanidad Penitenciaria","volume":"23 2","pages":"67-75"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/26/2013-6463-sanipe-23-02-67.PMC8592264.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39198716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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