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Relationship between CGOL (Chlorophyll, Ginger, Orange, and Lemongrass) consumption and confirmed COVID-19 cases on pregnant women CGOL(叶绿素、姜、橙、柠檬草)摄入与孕妇新冠肺炎确诊病例的关系
Pub Date : 2023-10-13 DOI: 10.4081/hls.2023.11749
Diyan Indriyani, Esti Yunitasari, Ferry Efendi
Nutritional status and health are crucial factors in maintaining a healthy pregnancy, especially during the COVID-19 pandemic. This study aimed to analyze the relationship between CGOL (Chlorophyll, Ginger, Orange, and Lemongrass) consumption and confirmed COVID-19 cases in pregnant women. The research, conducted in East Java with 250 purposively sampled respondents, employed a correlational cross-sectional design. Data were collected through questionnaires, Likert scales, and documentation. Analysis of research data using descriptive analysis and Spearman-Rho analyses. The study revealed that CGOL consumption in pregnant women was 28% less than optimal, 21.2% moderate and 50.8% optimal. Confirmed COVID-19 cases in pregnant women are 10%, and 90% are not confirmed. There was a significant relationship between CGOL consumption and confirmation of COVID-19 in pregnant women (p-value=0.0001). These findings emphasize the importance of integrating CGOL-based nutritional guidelines into prenatal care programs, particularly during pandemics, to enhance pregnant women's and their babies' health.
营养状况和健康是维持健康妊娠的关键因素,特别是在COVID-19大流行期间。本研究旨在分析CGOL(叶绿素、生姜、橙子和柠檬草)摄入量与孕妇确诊COVID-19病例之间的关系。这项研究在东爪哇进行,有目的地抽样了250名受访者,采用了相关横断面设计。通过问卷调查、李克特量表和文献收集数据。使用描述性分析和Spearman-Rho分析研究数据。研究显示,孕妇的CGOL摄取量低于最佳摄取量28%,中等摄取量21.2%,最佳摄取量50.8%。孕妇中确诊的COVID-19病例占10%,未确诊病例占90%。孕妇CGOL摄入量与COVID-19确诊之间存在显著相关性(p值=0.0001)。这些发现强调了将基于cgo的营养指南纳入产前护理方案的重要性,特别是在大流行期间,以增强孕妇及其婴儿的健康。
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引用次数: 0
Relationship between nurses knowledge level and workload about implementation of patient identification 护士知识水平与患者身份识别实施工作量的关系
Pub Date : 2023-10-12 DOI: 10.4081/hls.2023.11756
Arsyawina Arsyawina, Hilda Hilda, Supriadi Supriadi, Hesti Prawita Widiastuti, Annisa Syaputri, Joko Sapto Pramono
Patient safety incidents can originate from patient identification errors. From the preliminary study, it was found that there were 3 cases of patient identification errors in the year 2022. The objective of this research was to determine the relationship between nurses knowledge level and workload with patient identification implementation. This study employed a quantitative method with a cross-sectional research design. This research aims to analyze the relationship between variables where the independent variable and dependent variable are identified at one unit of time. In this case, to determine the relationship between the level of knowledge and workload of nurses with the implementation of patient identification. The sample consisted of 93 individuals distributed across the inpatient wards. The research sample was selected used random sampling. The knowledge level and workload of nurses were independent variables, while the implementation of patient identification was the dependent variable. Data collected was used of a level of knowledge, workload, and application of identification questionnaire. Data analyzed used were with Chi-square test. The obtained p-value for the relationship between nurses knowledge level and the implementation of patient identification is p=0.018 (p<0.05). Therefore, there is a significant relationship between nurses knowledge level and the implementation of patient identification. P-value for the relationship between nurses workload and the implementation of patient identification is p=0.564 (p>0.05). This explains that there is no significant relationship between nurses workload and the implementation of patient identification. There is a significant relationship between nurses knowledge level and the implementation of patient identification. The majority of nurses demonstrated a good implementation of patient identification. It is recommended for the hospital management to make efforts to improve nurses knowledge, especially in the area of patient safety.
患者安全事件可能源于患者识别错误。从初步研究中发现,在2022年有3例患者识别错误。本研究的目的是确定护士的知识水平和工作量与病人识别的实施之间的关系。本研究采用横断面研究设计的定量方法。本研究旨在分析在单位时间内识别自变量和因变量的变量之间的关系。在这种情况下,确定护士的知识水平和工作量与实施患者识别的关系。样本由分布在住院病房的93个人组成。研究样本选取采用随机抽样。护士的知识水平和工作量为自变量,患者识别的实施为因变量。收集的数据用于知识水平、工作量和识别问卷的应用。数据分析采用卡方检验。得到的护士知识水平与患者识别实施情况关系的p值为p=0.018 (p<0.05)。因此,护士的知识水平与患者识别的实施有显著的关系。护士工作量与患者识别实施的关系p值为p=0.564 (p>0.05)。这解释了护士工作量与患者身份识别的实施之间没有显著的关系。护士知识水平与患者身份识别的实施有显著关系。大多数护士表现出良好的患者识别执行情况。建议医院管理层努力提高护士的知识,特别是在患者安全方面。
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引用次数: 0
The effect of ethanol extract of <i>Cosmos caudatus</i> leaves on the percentage of the cell cycle in <i>Candida albicans</i> culture 山茱萸乙醇提取物对山茱萸的影响叶片在白色念珠菌细胞周期中的百分比&lt;i&gt;文化
Pub Date : 2023-10-12 DOI: 10.4081/hls.2023.11754
Lidia Lushinta, Heni Suryani
Candidiasis is a common fungal gynecological disease among humans. The use of antifungal agents, such as Fluconazole, has been reported to increase resistance to candidiasis by 7%. This study aimed to investigate the effect of antifungal flavonoids from Cosmos caudatus leaf extract on the cell cycle percentage in C. albicans culture. This research employed a true experimental post-test only with a control group design. The C. albicans isolate was obtained from the Microbiology Laboratory under the code C. albicans SV-1148. The isolates were cultured in Sabouraud Dextrose Agar (SDA) medium and Sabouraud Dextrose Broth (SDB). The sample group was divided into a negative control group, a positive control group with fluconazole (60 µg/ml), and a treatment group with various concentrations of ethanol extract from Kenikir leaves (C. caudatus Kunth.) - 5%, 10%, 20%, 40%, and combinations (20% ethanol extract from Kenikirleaves + 30 µg/ml Fluconazole). This study revealed a reduction in the percentage of cell cycles in the S phase (DNA synthesis) in the treatment group receiving ethanol extract from Kenikir leaves (C. caudatus Kunth.) and the combination treatment group compared to the negative control group. The study suggests that this decrease in the percentage of cell cycles results from DNA damage caused by the presence of flavonoids in Kenikir leaves (C. caudatus Kunth.). Kenikirleaves (C. caudatus Kunth.) have the potential to decrease the percentage of S-phase cell cycles (DNA synthesis) in the culture of C. albicans. This research demonstrates that Kenikir leaves (C. caudatus Kunth.) contain natural flavonoids with antifungal properties and have the potential to be used as an alternative medicine for candidiasis in humans. It is hoped that incorporating Kenikir as a food ingredient can serve as an alternative prevention and treatment approach for candidiasis.
念珠菌病是人类常见的真菌性妇科疾病。据报道,使用氟康唑等抗真菌药物可使对念珠菌病的耐药性增加7%。本研究旨在探讨尾叶提取物中抗真菌黄酮类化合物对白色念珠菌培养细胞周期百分比的影响。本研究采用真正的实验后测,仅采用对照组设计。分离的白色念珠菌从微生物学实验室获得,鉴定代码为C. albicans SV-1148。分离菌株分别在Sabouraud Dextrose Agar (SDA)培养基和Sabouraud Dextrose Broth (SDB)培养基中培养。样品组分为阴性对照组、氟康唑(60µg/ml)阳性对照组和不同浓度的肯尼柯尔叶乙醇提取物(5%、10%、20%、40%和组合(肯尼柯尔叶20%乙醇提取物+ 30µg/ml氟康唑)治疗组。本研究发现,与阴性对照组相比,接受Kenikir叶(C. caudatus Kunth.)乙醇提取物的处理组和联合处理组在S期(DNA合成)的细胞周期百分比减少。该研究表明,细胞周期百分比的减少是由Kenikir叶(C. caudatus Kunth.)中黄酮类化合物的存在引起的DNA损伤引起的。Kenikirleaves (C. caudatus Kunth.)有可能降低白色念珠菌培养中s期细胞周期(DNA合成)的百分比。本研究表明,Kenikir叶(C. caudatus Kunth.)含有具有抗真菌特性的天然黄酮类化合物,有潜力作为人类念珠菌病的替代药物。希望将Kenikir作为一种食品成分可以作为一种预防和治疗念珠菌病的替代方法。
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引用次数: 0
Does satisfaction with the manual wheelchair have an impact on the quality of life in spinal cord injury? 对手动轮椅的满意度对脊髓损伤患者的生活质量有影响吗?
Pub Date : 2023-10-10 DOI: 10.4081/hls.2023.11526
Beenish Mehmood
Background: Customised wheelchairs are integral component for comprehensive rehabilitation and community integration for spinal cord injury (SCI) survivors, while inappropriate wheelchairs negatively impact their functional independence, mobility and quality of life (QOL). Keeping this in mind, this study aimed to determine the effects of manual wheelchair users' satisfaction on QOL in SCI. Methods: This cross-sectional study, which included 112 SCI, was conducted at the Paraplegic Centre, Hayatabad, Peshawar, over a period of 6 months using "Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST)" and “World Health Organisation Quality of Life (WHOQOL-BREF)” as study tools. Results: QUEST showed a significant positive correlation with physical health (rs = 0.375; p< 0.001), social relationships (rs=0.234; p = 0.013), and environmental health (rs = 0.462; p<0.001) of QOL except psychological health, and similarly, overall health and overall QOL was positively impacted. Furthermore, overall health and environmental, social relationships, and physical domains of QOL were statistically significantly impacted by the QUEST device and service aspects. Conclusion: A moderate level of satisfaction among participants for both devices and services was observed, which also impacts their physical, environmental, and social domains of QOL. Therefore, steps from the key stakeholders are required to provide satisfactory appropriate wheelchairs to patients so their QOL can be improved.
背景:定制轮椅是脊髓损伤(SCI)幸存者综合康复和社区融入不可或缺的组成部分,而不合适的轮椅会对他们的功能独立性、活动能力和生活质量(QOL)产生负面影响。考虑到这一点,本研究旨在确定手动轮椅使用者满意度对SCI患者生活质量的影响。 方法:本横断面研究包括112例SCI,在白沙瓦Hayatabad截瘫中心进行,为期6个月,使用“魁北克用户对辅助技术满意度评估(QUEST)”和“世界卫生组织生活质量(WHOQOL-BREF)”作为研究工具。结果:QUEST与身体健康呈显著正相关(rs = 0.375;术中;0.001),社会关系(rs=0.234;P = 0.013),环境卫生(rs = 0.462;(p < 0.001)对生活质量(除心理健康外)有显著影响,对整体健康和总体生活质量也有积极影响。此外,总体健康和环境、社会关系以及生活质量的物理领域受到QUEST设备和服务方面的统计显著影响。 结论:参与者对设备和服务的满意度都处于中等水平,这也影响了他们的身体、环境和社会生活领域。因此,需要关键利益相关者采取措施,为患者提供满意的适当轮椅,从而改善他们的生活质量。
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引用次数: 0
The effect of five activities daily living on improving cognitive function in ischemic stroke patients 日常生活五项活动对缺血性脑卒中患者认知功能改善的影响
Pub Date : 2023-10-10 DOI: 10.4081/hls.2023.11730
Frana Andrianur, Dwi Prihatin Era, Arifin Hidayat, Ismansyah Ismansyah, Diah Setiani
This study aimed to assess the effects of five activities of daily living (ADL) interventions on improving cognitive function in patients with ischemic stroke. The study employed a quasi-experimental design with 16 ischemic stroke patients (n=8 per group) in an inpatient ward at a regional hospital in Samarinda, Indonesia. Inclusion criteria were: i) confirmed ischemic stroke via medical records, ii) effective communication, iii) current inpatient status, and iv) hemiparesis. Data collection used an ADL activity instrument sheet, while cognitive function was assessed with the MoCA-Ina screening (maximum score: 30 points). Data analysis included the Wilcoxon test and independent T-Test, with significance set at p<0.05. After the intervention, the intervention group's cognitive function significantly improved (from mean 20.25 ± 2.60 to 25.13 ± 1.81), while the control group changed from mean 17.13 ± 2.10 to 20.50 ± 2.00. The intervention group showed a significant cognitive improvement compared to the control group (p < 0.05). In conclusion, ADL interventions enhance cognitive function in ischemic stroke patients, aiding recovery and serving as an effective hospital nursing intervention.
本研究旨在评估五种日常生活活动(ADL)干预对缺血性脑卒中患者认知功能改善的影响。该研究采用准实验设计,在印度尼西亚萨马林达地区医院的住院病房中对16名缺血性中风患者(每组8名)进行研究。纳入标准为:i)通过医疗记录确认缺血性卒中,ii)有效沟通,iii)当前住院状态,iv)偏瘫。数据收集采用ADL活动量表,认知功能评估采用MoCA-Ina筛查(最高分:30分)。数据分析采用Wilcoxon检验和独立t检验,显著性设置为p<0.05。干预后,干预组认知功能明显改善(从平均20.25±2.60提高到25.13±1.81),对照组从平均17.13±2.10提高到20.50±2.00。与对照组相比,干预组表现出显著的认知改善(p <0.05)。总之,ADL干预可提高缺血性脑卒中患者的认知功能,有助于康复,是一种有效的医院护理干预。
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引用次数: 0
Bay leaf decoction water and low-impact aerobic exercise impact on blood cholesterol levels 月桂叶煎水和低强度有氧运动对血液胆固醇水平的影响
Pub Date : 2023-10-10 DOI: 10.4081/hls.2023.11733
Ismansyah Ismansyah, Arifin Hidayat, Rini Ernawati
Hypercholesterolemia is a global health concern, including in Indonesia, potentially leading to coronary artery disease, heart failure, and stroke if left untreated. This study aimed to assess the effectiveness of bay leaf decoction and low-impact aerobic exercise on reducing blood cholesterol levels in patients. Used a quasi-experimental design with 120 participants, randomly assigned to two groups, the first group consumed bay leaf decoction (100 ml, twice daily for 7 days), while the second group underwent low-impact aerobic exercise (3 times a week for 7 days). Blood cholesterol levels were measured, and paired t-tests were employed for statistical analysis. Results revealed that both interventions significantly lowered cholesterol levels after 7 days (p<0.001 for bay leaf decoction and p=0.001 for low-impact aerobics). The bay leaf decoction group achieved the highest reduction at 25.3 mg/dl. In conclusion, this study highlights the potential of bay leaf decoction and low-impact aerobic exercise as non-pharmacological approaches to manage blood cholesterol levels. It reinforces the notion that these interventions can be valuable in addressing hypercholesterolemia.
高胆固醇血症是一个全球性的健康问题,包括在印度尼西亚,如果不及时治疗,可能导致冠状动脉疾病、心力衰竭和中风。本研究旨在评估月桂叶煎剂与低强度有氧运动对降低患者血胆固醇水平的有效性。采用准实验设计,120名受试者随机分为两组,第一组服用月桂叶煎剂(100 ml,每天2次,持续7天),第二组进行低冲击有氧运动(每周3次,持续7天)。测定血胆固醇水平,采用配对t检验进行统计分析。结果显示,两种干预措施在7天后显著降低了胆固醇水平(月桂叶煎剂p=0.001,低强度有氧运动p=0.001)。月桂叶煎剂组的降幅最大,为25.3 mg/dl。总之,这项研究强调了月桂叶煎剂和低强度有氧运动作为控制血液胆固醇水平的非药物方法的潜力。它强化了这些干预措施在解决高胆固醇血症方面是有价值的概念。
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引用次数: 0
Post-spinal hypotension management for cesarean section in low resource settings: efficiency and safety of two very low-dose boluses of norepinephrine, a randomized double-blinded controlled trial 低资源环境下剖宫产术后脊柱低血压管理:两种极低剂量去甲肾上腺素的有效性和安全性,一项随机双盲对照试验
Pub Date : 2023-09-21 DOI: 10.4081/hls.2023.11486
Feryel Benamor, Ines Elbekri, Sofiene Benmarzouk, Bochra Fouzai, Takwa Hkiri, Hayene Maghrebi
Spinal anesthesia is the gold standard anesthetic technique for cesarean section. However, its major complication is hypotension. Norepinephrine has recently been described as an efficient and safe alternative to Phenylephrine. The aim of this study was to determine the effective target bolus of Norepinephrine to prevent and treat post-spinal anesthesia hypotension. We conducted a prospective controlled randomized study including 126 parturients scheduled for cesarean delivery under spinal anesthesia. We compared two groups that received a prophylactic bolus of either 1μg/kg or 0.5μg/kg of Norepinephrine without fluid loading. The rescue intravenous bolus of Norepinephrine was half the dose of the prophylactic bolus. The main outcomes were the percentage of decrease in systolic and mean blood pressure. The secondary outcomes included the timing of the first hypotension, duration of hypotension, number of rescue boluses, total Norepinephrine consumption, incidence of hypotension and maternal adverse effects and fetal outcomes. Our primary outcome has shown similarities between groups; delta systolic blood pressure before delivery was 19.4% in group 1µg/kg versus 20.5% in group 0.5µg/kg. Both groups were similar for all secondary outcomes, except that the higher dose of Norepinephrine resulted in more hypertension. Fetal outcomes were similar in both groups. Bolus of 0.5μg/kg followed by rescue doses of 0.25μg/kg of Norepinephrine was efficient in preventing and treating spinal anesthesia-induced hypotension. These doses may be recommended for routine use in healthy parturients.
脊髓麻醉是剖宫产术的金标准麻醉技术。然而,其主要并发症是低血压。去甲肾上腺素最近被认为是一种有效和安全的苯肾上腺素替代品。本研究的目的是确定去甲肾上腺素预防和治疗脊髓麻醉后低血压的有效靶量。我们进行了一项前瞻性对照随机研究,包括126例脊柱麻醉下剖宫产的产妇。我们比较了两组接受预防性剂量1μg/kg或0.5μg/kg的去甲肾上腺素,没有液体负荷。去甲肾上腺素的抢救性静脉注射剂量是预防性注射剂量的一半。主要结果是收缩压和平均血压下降的百分比。次要结局包括首次低血压的时间、低血压持续时间、抢救剂量、去甲肾上腺素总消耗量、低血压发生率、母体不良反应和胎儿结局。我们的主要结果显示了各组之间的相似性;1µg/kg组分娩前δ收缩压为19.4%,0.5µg/kg组为20.5%。两组的所有次要结果相似,除了高剂量的去甲肾上腺素导致更多的高血压。两组胎儿结局相似。去甲肾上腺素0.5μg/kg灌注后0.25μg/kg抢救剂量能有效预防和治疗脊髓麻醉所致低血压。这些剂量可推荐用于健康孕妇的常规使用。
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引用次数: 0
Antioxidation and anti-inflammatory activities of blended essential oil 混合精油的抗氧化和抗炎活性
Pub Date : 2023-09-11 DOI: 10.4081/hls.2023.11548
Suriya Chaiwong, Kunthasaya Akkarasiritharattana, Khamjira Jarmkom, Punyanut Amorndoljai
The mixtures of essential oils are increasing popularly in holistic medicine. The different ratios of oil components in the preparation can result in different health benefits. Therefore, this study aimed to develop a mixture of essential oil formulation having promising bioactivities for pharmaceutical and cosmetic applications. The five popular essential oils including vetiver oil, lavender oil, eucalyptus oil, lemongrass oil, and phlai oil were selected for blended formulation. The selected oils were mixed in a suitable ratio and their antioxidant and anti-inflammatory activities were evaluated using 2,2-Diphenyl-1-picrylhydrazyl radical scavenging and nitric oxide (NO) radical scavenging, respectively. The prepared blended essential oil formulation had clear yellow-pale color and good smell. The blended oil showed good antioxidative activity by acting as a hydrogen donator. However, the blended oil presents mild anti-inflammatory activity via NO quenching action. The results of this study exposed that the developed blended essential oil formulation has promising properties to be used as a natural antioxidant as well as an anti-inflammatory agent in cosmetic and pharmaceutical applications.
精油的混合物在整体医学中越来越受欢迎。制剂中不同比例的油成分可产生不同的健康效益。因此,本研究旨在开发一种具有良好生物活性的混合精油制剂,用于制药和化妆品领域。选取香根草油、薰衣草油、桉树油、柠檬草油、佛莱油等5种流行精油进行混合配方。将所选油脂按适当比例混合,分别用清除2,2-二苯基-1-苦味酰肼基自由基和清除一氧化氮(NO)自由基的方法评价其抗氧化和抗炎活性。所制备的混合精油配方色泽黄淡,气味好。混合油作为供氢体表现出良好的抗氧化活性。然而,调和油通过NO猝灭作用表现出温和的抗炎活性。本研究结果表明,所开发的混合精油制剂在化妆品和制药应用中具有作为天然抗氧化剂和抗炎剂的良好性能。
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引用次数: 0
Fracture of the mandible treatment in a child: a simplified technique 儿童下颌骨骨折的治疗:一种简化技术
Pub Date : 2023-09-11 DOI: 10.4081/hls.2023.11304
Christoph H. Houben, Lundy Campbell, Chuol Chiok Stephen Kuol
After being hit by a motorcycle a seven-year old boy presented with a displaced fracture of the body of the right mandible [type III]. In the absence of orthodontic internal fixation or ligature wire equipment suture material was used to provide approximation and stabilisation of the fracture. The non-absorbable suture was fed through a cannula which was pierced through the bone on either side of the fracture. We present this simplified technique as a suitable alternative for the fixation of mandible fractures in settings with very limited resources.
一名七岁男孩被摩托车撞后,右侧下颌骨出现移位性骨折[III型]。在没有正畸内固定或结扎丝设备的情况下,使用缝合材料来提供骨折的近似和稳定。不可吸收缝合线通过一根穿过骨折两侧骨的套管置入。 我们提出这种简化的技术是在资源有限的情况下固定下颌骨骨折的一种合适的选择。
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引用次数: 0
Six-minute step test performance in asymptomatic adults 无症状成人六分钟步测试表现
Pub Date : 2023-09-11 DOI: 10.4081/hls.2023.11332
Riya Kalra, Kanu Goyal, Manu Goyal, Hina Vaish
The objectives of this study were i) to measure a six-minute step test (6MST) in asymptomatic adults; ii) to determine the applicability of Arcuri et al.’s reference equation to Indian adults; iii) to develop a prediction equation for Indian adults. 110 adult males and females aged 18-40 years were recruited for this prospective cross-sectional study conducted in India. Participants underwent 6MST. Applicability was assessed by comparing the findings of the 6MST with the values derived from Arcuri et al.’s predicted equations using the Bland-Altman plot. A multiple regression analysis was used to develop the prediction equation. The mean±SD six-minute step count was 159.42±17.60 steps and 150.78±14.39 steps in males and females respectively. The 6MST for males can be determined by males (steps)=204.371-1.521×age(years) and females (steps)=179.567-1.06×age (years). Arcuri et al.’s equation cannot be used to predict 6MST in Indian adults. Region-specific equations are useful to assess the values.
本研究的目的是:1)测量无症状成人的6分钟步频测试(6MST);ii)确定Arcuri等人的参考方程对印度成年人的适用性;iii)为印度成年人建立预测方程。在印度进行的这项前瞻性横断面研究招募了110名年龄在18-40岁的成年男性和女性。参与者接受6MST。通过比较6MST的结果与Arcuri等人使用Bland-Altman图预测方程的值来评估适用性。采用多元回归分析建立预测方程。男性和女性6分钟平均±SD步数分别为159.42±17.60步和150.78±14.39步。男性的6MST可以由男性(步)=204.371-1.521×age(年)和女性(步)=179.567-1.06×age(年)确定。Arcuri等人的公式不能用于预测印度成年人的6MST。区域特定方程对评估这些值是有用的。
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引用次数: 0
期刊
Healthcare in Lowresource Settings
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