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Inhibisie van osteoklastvorming en beenresorpsie deur poli-onversadigde vetsure in RAW 264.7 muismonosiete RAW 264.7小鼠单核细胞对破骨细胞形成和骨吸收的抑制作用
Pub Date : 2012-04-25 DOI: 10.4102/SATNT.V31I1.318
J. Boeyens, Wei-Hang Chua, M. Kruger, A. Joubert, M. Coetzee
Beenhermodellering in volwassenes is ‘n fisiologiese proses wat die sintese van beenmatriks deur osteoblaste en die resorpsie (afbraak) van been deur osteoklaste behels. Osteoklaste ontstaan deur die samesmelting van hematopoietiese selle van monosiet-makrofaagafkoms en speel ‘n deurslaggewende rol in beenhermodellering.
一种生理过程,通过成骨细胞控制术语中心,通过骨酶控制骨的吸收(流产)。成骨细胞通过收集单核细胞巨噬细胞的造血细胞而消失,并在BE模型中发挥半透明作用。
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引用次数: 0
Die invloed van ‘n intensiewe opleidingsprogram op die Kardio Stres-indeks 强化训练项目对心流指数的影响
Pub Date : 2012-03-06 DOI: 10.4102/satnt.v31i1.283
T. Claassen, E. Henning, M. Kleynhans, C. Grobbelaar, P. J. D. Toit
Mense ondervind baie stressors in hul alledaagse lewe, wat ‘n groot uitwerking het op daaglikse funksionering. Kardio Stres-indeks (KSI) is ‘n nie-indringende mate van die stres wat die hart ervaar. KSI (uitgedruk as ‘n persentasie) berekeninge word gebaseer op die duur van die QRS kompleks, hart tempo, ritme en standaardafwyking van die RR-interval (RRSD) spesifieke parameters.
人们在日常生活中发现了很多压力源,这对日常功能产生了巨大影响。心脏压力指数(KSI)是衡量影响心脏的压力的一个不兼容的指标。KSI(不推荐使用百分比)计算基于QRS波群的长度、心率、节律和RRSD间期(RRSD)特定参数的标准差。
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引用次数: 0
Molecular crosstalk between apoptosis and autophagy induced by a 2-methoxyestradiol analogue (C19) in HeLa cells 2-甲氧基雌二醇类似物(C19)诱导HeLa细胞凋亡和自噬之间的分子串扰
Pub Date : 2012-03-04 DOI: 10.4102/SATNT.V31I1.315
A. Theron, M. Visagie, T. Mqoco, A. Stander, R. Prudent, L. Lafanechère, A. Joubert
Servikale kanker is gerapporteer deur die Wereld Gesondheids Organisasie as die mees algemene tipe kanker wat vroue in armer sosio-ekonomiese lande affekteer.
世界卫生组织已将癌症列为影响贫穷社会经济国家妇女的最常见的癌症。
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引用次数: 0
Partikel-Swerm-Optimering (PSO) toetsbank vir globale wiskundige minimeringsprobleme 全局科学极小化问题的部分扫描优化(PSO)测试库
Pub Date : 2011-11-11 DOI: 10.4102/SATNT.V30I1.102
Ludwig de Bruin, E. M. Ehlers
’n Partikel-Swerm-Optimering (PSO) toetsbank is ontwikkel om verskillende algoritmes te vergelyk. Die toetsbank stel ons in staat om te bepaal watter tipe algoritmes verskillende probleme die beste oplos. Hierdie referaat sal eerstens wiskundige optimering definieer, kortliks PSO verduidelik, die toetsbankstelsel opsom en laastens na resultate verwys.
PSO密钥已被开发用于比较不同的算法。这是一个最好的解决方案。本参考文献将首先定义数学优化,简要解释PSO、输入输出系统。
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引用次数: 0
Voorwerp-rekonstruksie vanaf verskeie onbeheerde sigpunte 从各种未处理的点重建对象
Pub Date : 2011-10-27 DOI: 10.4102/SATNT.V30I1.262
D. Joubert
CITATION: Joubert, D. 2011. Voorwerp-rekonstruksie vanaf verskeie onbeheerde sigpunte. Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie, 30(1), Art. #262, doi:10.4102/satnt.v30i1.262.
引文:Joubert,D.2011。从各种未处理的点重建对象。南非自然账户和技术时间字体,30(1),第262条,doi:10.4102/satnt.v30i1.262。
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引用次数: 0
Experimental measurement and modelling of vapour-liquid equilibrium data for the C2F4-C3F6-s-C4F8 system C2F4-C3F6-s-C4F8体系气液平衡数据的实验测量与建模
Pub Date : 2011-10-11 DOI: 10.4102/SATNT.V30I1.99
F. Conradie
The following members formed part of the committee that was responsible for arranging the symposium: Mr. R. Pretorius (Department of Geography, University of South-Africa), Dr E. Snyders (NECSA), Dr M. Landman (Department of Chemistry, University of Pretoria) and Dr W. Meyer (Department of Physics, University of Pretoria). Experimental measurement and modelling of vapour-liquid equilibrium data for the C2F4-C3F6-s-C4F8 system The vapour-liquid equilibrium data for the C2F4-C3F6-s-C4F8 system are presented. Each binary system was evaluated at three isotherms. The experimental data will be correlated to the Peng-Robinson equation of state, incorporating the Mathias-Copeman alpha function, with the Wong-Sandler mixing rule utilising the NRTL activity coefficient model. Page 1 of 1
下列成员组成了负责安排研讨会的委员会:R. Pretorius先生(南非大学地理系)、E. Snyders博士(南非国家环境研究所)、M. Landman博士(比勒陀利亚大学化学系)和W. Meyer博士(比勒陀利亚大学物理系)。介绍了C2F4-C3F6-s-C4F8体系的气液平衡数据的实验测量和建模。每个双星系统在三条等温线上进行评估。实验数据将与包含Mathias-Copeman alpha函数的Peng-Robinson状态方程和利用NRTL活度系数模型的Wong-Sandler混合规则相关联。第1页/ 1
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引用次数: 0
From the Fermat points to the De Villiers3 points of a triangle 从费马点到三角形的德维利尔点
Pub Date : 2010-01-13 DOI: 10.4102/satnt.v29i3.16
M. Villiers
The article starts with a problem of finding a point that minimizes the sum of the distances to the vertices of an acute-angled triangle, a problem originally posed by Fermat in the 1600’s, and apparently first solved by the Italian mathematician and scientist Evangelista Torricelli. This point of optimization is therefore usually called the inner Fermat or Fermat-Torricelli point of a triangle. The transformation proof presented in the article was more recently invented in 1929 by the German mathematician J. Hoffman. After reviewing the centroid and medians of a triangle, these are generalized to Ceva’s theorem, which is then used to prove the following generalization of the Fermat-Torricelli point from [3]: “If triangles DBA, ECB and FAC are constructed outwardly (or inwardly) on the sides of any ∆ABC so that ∠DAB =∠CAF , ∠ DBA = ∠ CBE and ∠ ECB = ∠ ACF then DC, EA and FB are concurrent.”However, this generalization is not new, and the earliest proof the author could trace is from 1936 by W. Hoffer in [1], though the presented proof is distinctly different. Of practical relevance is the fact that this Fermat-Torricelli generalization can be used to solve a “weighted” airport problem, for example, when the populations in the three cities are of different size. The author was also contacted via e-mail in July 2008 by Stephen Doro from the College of Physicians and Surgeons, Columbia University, USA, who was considering its possible application in the branching of larger arteries and veins in the human body into smaller and smaller ones. On the basis of an often-observed (but not generally true) duality between circumcentres and in centres, it was conjectured in 1996 [see 4] that the following might be true from a similar result for circumcentres (Kosnita’s theorem), namely: The lines joining the vertices A, B, and C of a given triangle ABC with the incentres of the triangles BCO, CAO, and ABO (O is the incentre of ∆ABC), respectively, are concurrent (in what is now called the inner De Villiers point). Investigation on the dynamic geometry program Sketchpad quickly confi rmed that the conjecture was indeed true. (For an interactive sketch online, see [7]). Using the aforementioned generalization of the Fermat-Torricelli point, it was now also very easy to prove this result. The outer De Villiers point is similarly obtained when the excircles are constructed for a given triangle ABC, in which case the lines joining the vertices A, B, and C of a given triangle ABC with the incentres of the triangles BCI1, CAI2, and ABI3 (Ii are the excentres of ∆ABC), are concurrent. The proof follows similarly from the Fermat-Torricelli generalization.
这篇文章的开头是一个问题,即找到一个点,使到锐角三角形顶点的距离总和最小,这个问题最初是由费马在17世纪提出的,显然是由意大利数学家和科学家埃万杰利斯塔·托里拆利首先解决的。因此,这个优化点通常被称为三角形的内费马点或费马-托里拆利点。这篇文章中提出的变换证明是在1929年由德国数学家霍夫曼(J. Hoffman)发明的。在考察了三角形的质心和中值之后,将它们推广到Ceva定理中,然后用Ceva定理证明了由[3]导出的费马-托里切利点的以下推广:“若三角形DBA、ECB和FAC在任意∆ABC的边向外(或向内)构造,使∠DAB =∠CAF、∠DBA =∠CBE、∠ECB =∠ACF,则DC、EA和FB同时存在。”然而,这种概括并不新鲜,作者所能找到的最早的证明是1936年W. Hoffer在b[1]的证明,尽管提出的证明明显不同。与实际相关的事实是,这种费马-托里拆利概化可以用于解决“加权”机场问题,例如,当三个城市的人口规模不同时。2008年7月,美国哥伦比亚大学内科和外科医学院的Stephen Doro通过电子邮件联系了作者,他正在考虑将其应用于人体大动脉和静脉分支成越来越小的动脉和静脉的可能性。的基础上一个时常观察到(但不是一般真实)之间的对偶外心在中心,1996年推测[4]看到以下可能是真的从一个类似的结果外心(Kosnita定理),即:行加入顶点a, B, C的一个给定三角形ABC的内心三角形BCO,曹,和ABO血型(O∆的内心是ABC),分别是并发(在现在称为内德Villiers点)。对动态几何程序Sketchpad的调查很快证实了这个猜想确实是正确的。(有关在线交互式草图,请参阅[7])。利用前面提到的费马-托里拆利点的推广,现在证明这个结果也很容易了。当为给定三角形ABC构造圆时,同样可以得到外德维利尔点,在这种情况下,将给定三角形ABC的顶点a, B和C与三角形BCI1, CAI2和ABI3的中心(Ii是∆ABC的中心)连接起来的线是并行的。这个证明类似地从费马-托里拆利推广中得出。
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引用次数: 0
The oxygen consumption rates of different life stages of the endoparasitic nematode 内寄生线虫不同生命阶段的耗氧量
Pub Date : 2010-01-13 DOI: 10.4102/SATNT.V29I1.4
W. V. Aardt, Donovan P. Loots, S. Steenkamp
Die suurstofverbruikskoers (VO2) van die endoparasitiese nematode Pratylenchus zeae versamel vanaf mieliewortelkulture is gemeet met behulp van ’n Cartesiese duiker. Die metings met die duiker wat uit Perspex gemasjineer is, berus in beginsel op manometriese veranderinge van die duiker in ’n flottasiebuis van ’n manometeropstelling.Die gemiddelde VO2van 10 metings per lewenstadium, uitgedruk in nanoliters per uur per lewenstadium van nie-anhidrobiote (eiers: 7.96; jeugstadia: 6.13; volwassenes: 26.04) is vergelyk met die van post-anhidrobiote, 12 uur na herstel uit anhidrobiose. Die gemiddelde VO2van die post-anhidrobiote vir die drie lewenstadia (eiers: 19.34; jeugstadia: 14.17; volwassenes: 32.86) is statisties betekenisvol hoer in vergelyking met die van nie-anhidrobiote. Die redes vir die verskil in VO2 waardes word bespreek. Die VO2 is ook uitgedruk in nanoliter per uur per mikrogram volwasse nematode na toepassing van ’n vergelyking verkry uit die literatuur. Dit is gevind dat die suurstofverbruik per een gram P. zeae 503 keer meer is as die suurstofverbruik per een gram soogdier die grootte van ’n volwasse bees.
体内寄生虫Pratylenchus zeae versamel vanaf mieliewortelkulture的宿主(VO2)是Cartesiese的宿主。有机玻璃对黑暗的测量是基于测压结构的柔性气泡中黑暗中的测压变化。VO2van的平均浓度为10毫克/升,单位为纳升/升/升(eiers:7.96;jeugstadia:6.13;volwassene:26.04)。三种生活状态(所有者:19.34;幼年状态:14.17;火山:32.86)的无水后疾病的平均VO2与非无水物质相比具有统计学意义。在VO2 waardes单词bespreek中,Die redes vir Die verskil。VO2也以每微克完整线虫每小时纳升的单位打印,以应用从文献中获得的方程。研究发现,每克玉米粉的土壤用量是每克土壤用量的503倍,高于一块牛肉的大小。
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引用次数: 1
Is studente wat in 'n uitkomsgerigte onderrigbenadering opgelei is, gereed vir universiteitswiskunde? : navorsings- en oorsigartikel 学生是否在大学学习?:导航和概览样式
Pub Date : 2009-12-01 DOI: 10.4102/satnt.v28i4.67
J. Engelbrecht, Ansie Harding, Patrick Phiri
Uitkomsgerigte onderrig (UGO) het 'n groei- en hersieningsfase beleef en is vir die afsienbare toekoms hier om te bly. Die 2009-inname van studente op universiteit is die eerste matrikulante wat slegs binne die nuwe bedeling onderrig ontvang het. Hierdie matrikulante se graad 12-uitslae is deur onnatuurlik hoe punte in wiskunde gekenmerk. Die vraag wat gevra word, is hoe die 2009-inname van studente in wiskunde op universiteit vaar wat prestasie, algemene vaardighede, wiskundige vaardighede en inhoudverwante vaardighede betref. Dit blyk dat alhoewel hierdie studente beter toegerus is wat persoonlike eienskappe soos selfvertroue betref, hulle in baie gevalle swakker daaraan toe is wat wiskundige en inhoudverwante vaardighede betref. Voorstelle word gemaak om die oorgang van sekondere na tersiere wiskunde gladder te maak.Are students who have been educated in an outcomes-based approach prepared for university mathematics?Following the political changes of 1994 in South Africa, the decision was taken to replace the traditional skills-based education system at primary and secondary school level (Grades 1 - 12) with an outcomes-based education system (OBE). The OBE approach, referred to as Curriculum 2005, was introduced into schools in 1998. The implementation of the OBE system did not occur without problems, giving rise to revised initiatives and a fair amount of criticism. The 2009 intake of students at universities is the first group of students that had been subjected to the OBE approach for their entire school career. This is also the first group of students for whom some form of mathematics was compulsory up to Grade 12 level in the form of mathematics or mathematical literacy. These students were characterised by the fact that their mathematics marks for Grade 12 were exceptionally high and that many more students qualified for university entrance.This article reports on the impact of this new education system on the mathematics preparedness of students entering university. The study involves an empirical analysis of the students in the first-year mathematics course for engineering students at the University of Pretoria as well as an analysis of a questionnaire completed by experienced lecturers at this university.The question addressed in this article is how the 2009 intake of students cope with mathematics at university level with regard toPerformanceGeneral attributesMathematical attributesContent-related attributesResults indicate a decrease in mathematics performance of these students at university level and that the inflated matric marks result in unjustified expectations. However, it is not unusual for marks to decrease from school to university and there is still too little evidence for serious concern.The study also indicates that these students seem to be better equipped with regard to personal attributes such as self-confidence and the will to work. However, in many instances, their general mathematical attributes such as
Uitkomsgerigte onderrig(UGO)在她的职业生涯中取得了巨大的进步。2009年,在一所大学的学生宿舍里,她是一位母亲,她一直在床上睡觉。Hierdie matrikulante se graad 12 uitslae是在wiskunde gekenmerk的两名女子。Die vraag wat gevra word,是2009年在威斯康辛大学就读的一名学生,他是一名学生。这是一个非常好的学生,他是一个很好的学生。Voorstelle单词gemaak来自于一个叫vansekondre的单词。受过基于结果的教育的学生是否为大学数学做好了准备?1994年南非发生政治变化后,决定以成果教育制度取代传统的中小学(1-12年级)技能教育制度。OBE方法,即2005年课程,于1998年引入学校。OBE制度的实施并非没有问题,引发了修订后的举措和相当多的批评。2009年大学招收的学生是第一批在整个学校生涯中接受OBE方法的学生。这也是第一批以数学或数学素养的形式在12年级之前必须学习某种形式的数学的学生。这些学生的特点是,他们12年级的数学成绩非常高,有更多的学生有资格进入大学。本文报道了这种新的教育体系对进入大学的学生数学准备的影响。这项研究包括对比勒陀利亚大学工程系一年级数学课程学生的实证分析,以及对该大学经验丰富的讲师完成的问卷调查的分析。本文所要解决的问题是,2009年招收的学生如何应对大学数学水平的表现一般属性数学属性内容相关属性结果表明,这些学生在大学数学水平上的表现有所下降,过高的录取分数导致了不合理的期望。然而,分数从一所学校下降到另一所大学并不罕见,而且仍然没有太多证据值得严重关注。研究还表明,这些学生似乎在自信和工作意愿等个人特质方面更有能力。然而,在许多情况下,他们的一般数学属性,如代数操作技能和对数学写作的总体掌握程度,都比过去的学生差。还有一些领域,他们的内容知识要么缺乏,要么出乎意料地肤浅。因此,这些学生似乎提高了个人素质,但不一定具备支持他们的知识和数学技能。就处理这种情况提出了一些建议。很明显,新的学校制度需要从学校一级到大学一级进行变革,以确保过渡是可以克服的。
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引用次数: 2
Mathematical modelling: From school to university 数学建模:从中学到大学
Pub Date : 2009-09-07 DOI: 10.4102/SATNT.V28I4.71
A. Harding
The outcomes based education (OBE) system is characterised by controversy and the 2008 matric results that rendered admission to an unusually large number of students did nothing to silence critics. The first students who completed their full cycle of school education in the OBE system entered universities in 2009 and their preparedness for university mathematics as well as their performance at university level are important as indicaters for estimating the success or otherwise of the OBE system. In a previous study student performance in mathematics admission tests for 2005-2007 was investigated and it was found that students who had had partial exposure to OBE performed worse than had been the case with their predecessors in the categories of modelling and ratio problems. As a result, this study was conducted to investigate how the 2009 intake of students performed in a modelling course at university level. A report is presented which deals with student performance in the course, problems experienced, the effect of remedial intervention on performance and whether students of the OBE system are adequately prepared for mathematical modelling at university level. This study focuses on performance in a first year course in mathematical modelling at the University of Pretoria. The course is problem based and is technology intensive, requiring use of the software package Matlab. For investigative purposes the papers of semester tests 1 and 2 of 2005 were used unchanged for tests in 2009. Students of 2009 did not have access to the 2005 papers and the same lecturer taught students of both groups. The lecturer also noted personal experiences in respect of students and was able to draw reasonable comparisons between the 2009 students and previous groups because of her years of involvement with the course. The entrance requirement of 60% for matric mathematics in 2005 was increased to 70% in 2009. Results indicate that the pass percentage decreased in both semester tests from 2005 to 2009. The percentage of students with less than 40% also increased in both semester tests from 2005 to 2009. A surprising observation was that the percentage of students who excelled increased remarkably from 2005 to 2009 in both semester tests. Extra assistance was requested by students after the first semester test in 2009 and resulted in a week of intervention during which revision and extra problems were attended to. The results of the two semester tests of 2009 did not live up to expectations of the matric results of the group . Despite the exceptional matric results, performance in the modelling course was decidely poorer. Results indicate that most students were not adequately prepared for the course – as could be predicted from the previous study. The 2009 group was characterised by two aspects – excellent matric results on the one hand and full school education within the OBE system on the other. It is difficult to distinguish between the influence of the two
基于结果的教育(OBE)体系的特点是有争议的,2008年的高考结果导致了异常多的学生被录取,这并没有让批评者闭嘴。2009年,第一批在OBE系统中完成完整学校教育周期的学生进入大学,他们对大学数学的准备以及他们在大学水平上的表现是评估OBE系统成功与否的重要指标。在之前的一项研究中,对2005-2007年数学入学考试学生的成绩进行了调查,发现部分接触过出窍能力的学生在建模和比例问题方面的表现比他们的前辈要差。因此,本研究旨在调查2009年入学的大学生在大学水平的建模课程中的表现。该报告涉及学生在课程中的表现,遇到的问题,补救干预对表现的影响,以及OBE系统的学生是否为大学水平的数学建模做好了充分的准备。这项研究的重点是比勒陀利亚大学数学建模一年级课程的表现。该课程以问题为基础,技术密集,需要使用软件包Matlab。出于调查目的,2005年第1和第2学期考试的试卷在2009年的考试中保持不变。2009年的学生无法接触到2005年的论文,同一位讲师教授两组学生。讲师还提到了学生的个人经历,并能够将2009年的学生与以前的学生进行合理的比较,因为她多年来一直参与这门课程。高等数学的入学要求由2005年的60%提高至2009年的70%。结果表明,从2005年到2009年,两学期考试的通过率都有所下降。在2005年至2009年的两个学期测试中,成绩低于40%的学生比例也有所增加。一个令人惊讶的观察结果是,从2005年到2009年,在两个学期的测试中,优秀学生的比例显著增加。2009年第一学期考试结束后,学生们要求提供额外的帮助,这导致了一周的干预,在此期间,他们进行了复习和额外的问题。2009年两个学期的考试成绩没有达到小组的预期成绩。尽管取得了优异的成绩,但在建模课程上的表现却明显较差。结果表明,大多数学生没有为这门课程做好充分的准备,这一点可以从之前的研究中预测出来。2009年这批学生的特点有两个方面——一方面是优异的成绩,另一方面是在OBE体系内接受了完整的学校教育。很难区分这两个方面的影响。将2009年两个学期考试中“40岁以下”群体的庞大规模归咎于高于平均水平的分数,这是很方便的。然而,提高的入学要求应该弥补了高分。如果分数结果被认为是可靠的,那么就不能排除OBE系统对课程中表现不佳的学生的准备不足产生影响的可能性。相比之下,在成绩优异的学生中,如果这些学生受到了OBE系统的影响,对他们的表现会产生积极而不是消极的影响。看来,出窍勋章可能在好学生和差学生之间产生了两极分化的影响。好学生的表现特别好,差学生的表现比预期的要差。然而,草率地拒绝OBE制度是不公平的。对讲师的个人印象是,当他们需要帮助时,obe一代会寻求帮助,他们愿意尝试并利用他们的资源来为自己服务。
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引用次数: 0
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South African Journal of Science and Technology
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