Die doel van die studie was om die in vitro effekte van 2-metoksiestradiol-bis-sulfamaat op sellgroei, morfologie, reaktiewe suurstof spesie generasie en outofagie in ‘n borsepiteel adenokarsinoom (MCF-7) en ‘n nie-kankersellyn (MCF-12A) te ondersoek.
{"title":"In vitro invloed van 2-metoksiestradiol-bis-sulfamaat op selgroei, reaktiewe suurstof spesies produksie en outofagie induksie in ‘n borsepiteel adenokarsinoom sellyn en ‘n nie-kankeragtige borsepiteelsellyn","authors":"Michelle H. Visagie, A. Joubert","doi":"10.4102/SATNT.V31I1.303","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.303","url":null,"abstract":"Die doel van die studie was om die in vitro effekte van 2-metoksiestradiol-bis-sulfamaat op sellgroei, morfologie, reaktiewe suurstof spesie generasie en outofagie in ‘n borsepiteel adenokarsinoom (MCF-7) en ‘n nie-kankersellyn (MCF-12A) te ondersoek.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.303","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandra D. Nkandeu, T. Mqoco, M. Visagie, S. Marais, B. A. Stander, A. Joubert
This abstract was initially presented at the annual Biological Sciences Symposium, presented under the protection of the Suid-Afrikaanse Akademie vir Wetenskap en Kuns. The symposium was held at the University of Johannesburg on 01 October 2011.
这篇摘要最初发表在一年一度的生物科学研讨会上，由瑞典-南非荷兰语学院(Akademie vir Wetenskap en Kuns)保护。研讨会于2011年10月1日在约翰内斯堡大学举行。
{"title":"In vitro veranderinge in mitochondriale membraan potensiaal, aggresoom formasie en kaspase aktiwiteit deur `n nuwe 17-β-estradiol analoog in bors adenokarsinoomselle","authors":"Sandra D. Nkandeu, T. Mqoco, M. Visagie, S. Marais, B. A. Stander, A. Joubert","doi":"10.4102/SATNT.V31I1.297","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.297","url":null,"abstract":"This abstract was initially presented at the annual Biological Sciences \u0000Symposium, presented under the protection of the Suid-Afrikaanse Akademie vir Wetenskap en Kuns. The symposium was held at the \u0000University of Johannesburg on 01 October 2011.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.297","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Research on undergradute mathematics education is a relatively new field that originated less than 20 years ago in the United States of America (USA), and that is known under the acronymn RUME (Research in Undergraduate Mathematics Education). In South Africa researchers in this field form a small but strong group that originated at the University of Pretoria. In this article a brief overview is firstly given on the international increase in interest and activities in this research field. Secondly the research field is viewed from a South African perspective. Examples of research projects are discussed, as well as the career path that leads to research in this field. Finally local activities and existing international ties are considered. The aim of this article is to give a South African overview of the research field and activities, hoping to motivate and stimulate research in this important and growing field.
本科数学教育研究是一个相对较新的领域，起源于美国(USA)不到20年的时间，简称RUME (Research in Undergraduate mathematics education)。在南非，这一领域的研究人员组成了一个小而强大的团体，起源于比勒陀利亚大学。本文首先简要概述了国际上对这一研究领域的兴趣和活动的增加。其次，从南非的角度来看待研究领域。研究项目的例子进行了讨论，以及职业道路，导致在这个领域的研究。最后考虑了当地活动和现有的国际联系。本文的目的是对南非的研究领域和活动进行概述，希望能够激励和刺激这一重要且不断发展的领域的研究。
{"title":"Research on undergraduate mathematics education: A South African perspective.","authors":"A. Harding, J. Engelbrecht","doi":"10.4102/SATNT.V31I1.358","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.358","url":null,"abstract":"Research on undergradute mathematics education is a relatively new field that originated less than 20 years ago in the United States of America (USA), and that is known under the acronymn RUME (Research in Undergraduate Mathematics Education). In South Africa researchers in this field form a small but strong group that originated at the University of Pretoria. In this article a brief overview is firstly given on the international increase in interest and activities in this research field. Secondly the research field is viewed from a South African perspective. Examples of research projects are discussed, as well as the career path that leads to research in this field. Finally local activities and existing international ties are considered. The aim of this article is to give a South African overview of the research field and activities, hoping to motivate and stimulate research in this important and growing field.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2012-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70516050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Die sintese van ‘n nuut in silico -ontwerpte antimitotiese verbinding, C19, wat spesifiek ontwerp is om selektief te bind aan die kanker geassosieerde koolsuuranhidrase IX (CAIX) proteien is uitgevoer deur Ithemba Farmaseutiese maatskappy.
{"title":"Signaling pathways involved in the induction of cell death in breast cell lines by a novel carbonic anhydrase 9 inhibitor or antimitotic compound","authors":"B. A. Stander, F. Joubert, A. Joubert","doi":"10.4102/SATNT.V31I1.342","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.342","url":null,"abstract":"Die sintese van ‘n nuut in silico -ontwerpte antimitotiese verbinding, C19, wat spesifiek ontwerp is om selektief te bind aan die kanker geassosieerde koolsuuranhidrase IX (CAIX) proteien is uitgevoer deur Ithemba Farmaseutiese maatskappy.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2-Etiel-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-3-ol-17 (C9) is ‘n nuwe,in silico-ontwerpte, antimitotiese 17-beta-estradiolderivaat. Dichloro-asetielsuur (DCA) inhibeer pirovaat dehydrogenase kinase ensiem aktiwiteit wat die vorming en vervoer van asetiel-KoA in die mitochondria inhibeer. Dit veroorsaak dat fermentasie prosesse, wat in kankerselle bevoordeel word, onderdruk word.
{"title":"In vitro seintransduksie meganisme uitgeoefen deur 2-etiel-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-3-ol-17-een in kombinasie met ‘n dichloro-asetielsuur op die bors adenokarsinoom (MCF-7) en bors nie-tumorigene (MCF-12A) selle","authors":"X. X. Stander, A. Stander, A. Joubert","doi":"10.4102/SATNT.V31I1.343","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.343","url":null,"abstract":"2-Etiel-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-3-ol-17 (C9) is ‘n nuwe,in silico-ontwerpte, antimitotiese 17-beta-estradiolderivaat. Dichloro-asetielsuur (DCA) inhibeer pirovaat dehydrogenase kinase ensiem aktiwiteit wat die vorming en vervoer van asetiel-KoA in die mitochondria inhibeer. Dit veroorsaak dat fermentasie prosesse, wat in kankerselle bevoordeel word, onderdruk word.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.343","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Spinnekoppe van die genus Cyrtophora vorm deel van die familie Araneidae en staan algemeen bekend as tent-web spinnekoppe te danke aan die unieke vorm van hul web. ‘n Totaal van 41 Cyrtophora spp. is in die hele wereld bekend en vyf van hulle is uit Afrika aangeteken, maar geen formeel in Suid-Afrika nie.
Cyrtophora属的头部是Araneidae科的一部分，人们通常会感谢其网站的独特形式，因为它们的网页旋转按钮。”在Totaal van 41 Cyrtophora spp.中，有一种是在非洲发现的。
{"title":"Genetic, morphologic and behavioral study of Cyrtophora spp . (Araneae: Araneidae) in South Africa","authors":"P. Franzini, H. Bank, A. Dippenaar-Schoeman","doi":"10.4102/SATNT.V31I1.339","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.339","url":null,"abstract":"Spinnekoppe van die genus Cyrtophora vorm deel van die familie Araneidae en staan algemeen bekend as tent-web spinnekoppe te danke aan die unieke vorm van hul web. ‘n Totaal van 41 Cyrtophora spp. is in die hele wereld bekend en vyf van hulle is uit Afrika aangeteken, maar geen formeel in Suid-Afrika nie.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.339","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. S. Dippenaar-Schoeman, Stefan H. Foord, C. Haddad
Die Savanna Bioom beslaan die grootste oppervlakte in Suid-Afrika en bedek meer as een derde van die grondoppervlakte. Dit word deur ‘n graslaag met bome gekenmerk. Waar die plantegroei deurgaans kort is staan dit bekend as bossieveld, teenoor die oop boslandskap met groter bome, en die bosveld met korter bome. Die faktore wat ‘n beperking het op die Savanna Bioom is reenval wat wissel van 235 mm tot 1000 mm per jaar; landbou-ontwikkeling en oorbeweiding.
{"title":"Spinnekopdiversiteit van die Suid-Afrikaanse Savanna Bioom","authors":"A. S. Dippenaar-Schoeman, Stefan H. Foord, C. Haddad","doi":"10.4102/SATNT.V31I1.338","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.338","url":null,"abstract":"Die Savanna Bioom beslaan die grootste oppervlakte in Suid-Afrika en bedek meer as een derde van die grondoppervlakte. Dit word deur ‘n graslaag met bome gekenmerk. Waar die plantegroei deurgaans kort is staan dit bekend as bossieveld, teenoor die oop boslandskap met groter bome, en die bosveld met korter bome. Die faktore wat ‘n beperking het op die Savanna Bioom is reenval wat wissel van 235 mm tot 1000 mm per jaar; landbou-ontwikkeling en oorbeweiding.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.338","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
As gevolg van die troeteldiermark en voedselbedryf is sommige varswaterskilpaaie wereldwyd versprei. Onvolwasse skilpaaie is dikwels baie aantreklik en kleurvol, maar hulle is geneig om hulle helder kleure te verloor hoe ouer hulle word.
{"title":"Impak van indringer parasiete op die biologie en bewaring van inheemse varswaterskilpaaie in Suid-Afrika en Frankryk","authors":"L. Meyer, Louis H. Du Preez, Olivier Verneau","doi":"10.4102/SATNT.V31I1.325","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.325","url":null,"abstract":"As gevolg van die troeteldiermark en voedselbedryf is sommige varswaterskilpaaie wereldwyd versprei. Onvolwasse skilpaaie is dikwels baie aantreklik en kleurvol, maar hulle is geneig om hulle helder kleure te verloor hoe ouer hulle word.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.325","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Die Mollusca is die tweede grootste dierfilum. Dit sluit meer as 35 000 fossiel en 100 000 lewende spesies in. Die doel van hierdie studie was om ‘n opname te maak van die mosselkrewels, inheemse en uitlandse slakspesies op die eiland.
《软体动物》是第二大动物电影。在10万个物种中，有3.5万个化石。这项研究的名字是“maak van Die mosselkrewels”，这是一项研究。
{"title":"A survey and DNA barcoding of the molluscs and barnacles of Robben Island","authors":"F. H. Bank, R. Greenfield","doi":"10.4102/SATNT.V31I1.313","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.313","url":null,"abstract":"Die Mollusca is die tweede grootste dierfilum. Dit sluit meer as 35 000 fossiel en 100 000 lewende spesies in. Die doel van hierdie studie was om ‘n opname te maak van die mosselkrewels, inheemse en uitlandse slakspesies op die eiland.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"121 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.313","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. A. Breedt, Ivan Brewer, A. Coetzer, L. V. D. Walt, S. S. Cilliers
Verstedeliking en die gepaardgaande antropogeniese impakte op ekosisteme neem voortdurend toe en tree as ‘n sterk selektiewe krag op wat plant-spesiediversiteit, ruimtelike verspreiding, funksionaliteit en gedrag van plantspesies beinvloed.
{"title":"Landskapsfunksionaliteit en plantdiversiteit in stedelike en landelike gefragmenteerde grasvelde in die Potchefstroom omgewing","authors":"J. A. Breedt, Ivan Brewer, A. Coetzer, L. V. D. Walt, S. S. Cilliers","doi":"10.4102/SATNT.V31I1.279","DOIUrl":"https://doi.org/10.4102/SATNT.V31I1.279","url":null,"abstract":"Verstedeliking en die gepaardgaande antropogeniese impakte op ekosisteme neem voortdurend toe en tree as ‘n sterk selektiewe krag op wat plant-spesiediversiteit, ruimtelike verspreiding, funksionaliteit en gedrag van plantspesies beinvloed.","PeriodicalId":30428,"journal":{"name":"South African Journal of Science and Technology","volume":"31 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2012-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4102/SATNT.V31I1.279","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70515511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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