首页 > 最新文献

Saude Tecnologia最新文献

英文 中文
Breve caracterização da situação profissional dos licenciados em ortoprotesia pela ESTeSL entre 2004/2005 e 2012/2013 2004/2005年至2012/2013年间,ESTeSL整形外科毕业生的专业状况简介
Pub Date : 2016-02-15 DOI: 10.25758/SET.1274
Salomé Silva, A. Rodrigues, Fani Ferreira, S. Pacheco, J. Matos
Introduction – Nowadays the high unemployment rate and the emigration of young graduated population is the reason why this population has been insecure about their career and professional future in their home country. By some way the existence of a reflexive analysis about their actual professional situation could clarify the future for students and recently-graduated in prosthetics and orthotics area. Objectives – Quantifying the professional situation of the graduated population in prosthetics and orthotics on Escola Superior de Tecnologia da Saude de Lisboa (ESTeSL) and also create a reflection tool about future professional perspectives. Methodology – Application of a questionnaire through the platform LimeSurvey® to the universe of prosthetists and orthotists graduates in ESTeSL and characterize by the quantitative data. Results/Discussion – The majority of the graduates are young and females. 78.3% of the inquired are working on the prosthetics and orthotics area and the unemployment rate is 8.7%. It’s notice a geographical mobility to the district of Lisbon to study and to work. Conclusion – The unemployment rate in prosthetics and orthotics graduates is lower than the national average. In opposition with another graduated health groups, the National Health System is a minor employer of these population. It was noticed a desertification of the big urban centres, in what concerns to the first job and actual job
引言-如今的高失业率和年轻毕业生人口的移民是这个人口在他们的祖国对他们的职业和职业未来不安全的原因。在某种程度上,对他们的实际专业情况进行反身性分析,可以为义肢和矫形学专业的学生和刚毕业的学生指明未来。目标-量化里斯本高等科技大学(ESTeSL)义肢和矫形学毕业生的专业状况,并创建一个关于未来专业前景的反思工具。方法-通过limessurvey®平台对ESTeSL的义肢师和矫形师毕业生进行问卷调查,并通过定量数据进行表征。结果/讨论-大多数毕业生是年轻人和女性。78.3%的被调查者在假肢矫形器领域工作,失业率为8.7%。人们注意到里斯本地区的地理流动性,以学习和工作。结论:我国义肢矫形专业毕业生的失业率低于全国平均水平。与另一个毕业卫生组织相反,国家卫生系统是这些人口的次要雇主。人们注意到大城市中心的沙漠化,这涉及到第一份工作和实际工作
{"title":"Breve caracterização da situação profissional dos licenciados em ortoprotesia pela ESTeSL entre 2004/2005 e 2012/2013","authors":"Salomé Silva, A. Rodrigues, Fani Ferreira, S. Pacheco, J. Matos","doi":"10.25758/SET.1274","DOIUrl":"https://doi.org/10.25758/SET.1274","url":null,"abstract":"Introduction – Nowadays the high unemployment rate and the emigration of young graduated population is the reason why this population has been insecure about their career and professional future in their home country. By some way the existence of a reflexive analysis about their actual professional situation could clarify the future for students and recently-graduated in prosthetics and orthotics area. Objectives – Quantifying the professional situation of the graduated population in prosthetics and orthotics on Escola Superior de Tecnologia da Saude de Lisboa (ESTeSL) and also create a reflection tool about future professional perspectives. Methodology – Application of a questionnaire through the platform LimeSurvey® to the universe of prosthetists and orthotists graduates in ESTeSL and characterize by the quantitative data. Results/Discussion – The majority of the graduates are young and females. 78.3% of the inquired are working on the prosthetics and orthotics area and the unemployment rate is 8.7%. It’s notice a geographical mobility to the district of Lisbon to study and to work. Conclusion – The unemployment rate in prosthetics and orthotics graduates is lower than the national average. In opposition with another graduated health groups, the National Health System is a minor employer of these population. It was noticed a desertification of the big urban centres, in what concerns to the first job and actual job","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"65 1","pages":"42-46"},"PeriodicalIF":0.0,"publicationDate":"2016-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Radioimunoterapia: uma abordagem terapêutica promissora no tratamento do carcinoma do ovário 放射免疫疗法:一种很有前途的治疗卵巢癌的方法
Pub Date : 2016-02-15 DOI: 10.25758/SET.1244
Carolina Rodrigues, Maria Cristina Oliveira
Ovarian carcinoma is the fifth leading cause of cancer death in women and is the leading cause among gynecologic malignancies. Factors such as the molecular heterogeneity of ovarian tumors and initial diagnosis at advanced stages hamper effective disease treatment. Given the ineffectiveness of current treatments, the development of newer therapeutic modalities for effective ovarian cancer treatment is still needed. Radioimmunotherapy that combines the use of monoclonal antibodies against tumor-associated antigens with the cytotoxic properties of therapeutic radionuclides could be one of these approaches. The potential of monoclonal antibodies to complement current treatment protocols may bring a significant improvement to the overall therapeutic outcomes of the disease. The aim of the present review is to give an overview of published clinical trials of radioimmunotherapy for the treatment of ovarian carcinoma
卵巢癌是妇女癌症死亡的第五大原因,也是妇科恶性肿瘤的主要原因。卵巢肿瘤的分子异质性和晚期的初步诊断等因素阻碍了有效的疾病治疗。鉴于目前的治疗无效,卵巢癌有效治疗的新治疗方式的发展仍然是必要的。放射免疫治疗结合使用单克隆抗体对抗肿瘤相关抗原与治疗放射性核素的细胞毒性特性可能是这些方法之一。单克隆抗体补充当前治疗方案的潜力可能会显著改善该疾病的整体治疗结果。本综述的目的是对已发表的放射免疫治疗卵巢癌的临床试验进行综述
{"title":"Radioimunoterapia: uma abordagem terapêutica promissora no tratamento do carcinoma do ovário","authors":"Carolina Rodrigues, Maria Cristina Oliveira","doi":"10.25758/SET.1244","DOIUrl":"https://doi.org/10.25758/SET.1244","url":null,"abstract":"Ovarian carcinoma is the fifth leading cause of cancer death in women and is the leading cause among gynecologic malignancies. Factors such as the molecular heterogeneity of ovarian tumors and initial diagnosis at advanced stages hamper effective disease treatment. Given the ineffectiveness of current treatments, the development of newer therapeutic modalities for effective ovarian cancer treatment is still needed. Radioimmunotherapy that combines the use of monoclonal antibodies against tumor-associated antigens with the cytotoxic properties of therapeutic radionuclides could be one of these approaches. The potential of monoclonal antibodies to complement current treatment protocols may bring a significant improvement to the overall therapeutic outcomes of the disease. The aim of the present review is to give an overview of published clinical trials of radioimmunotherapy for the treatment of ovarian carcinoma","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"26-35"},"PeriodicalIF":0.0,"publicationDate":"2016-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
O tratamento de metástases ósseas de fração única vs múltiplas frações com 3D CRT ou SBRT: artigo de revisão sistemática 三维CRT或SBRT治疗单组分与多组分骨转移:系统综述文章
Pub Date : 2016-02-15 DOI: 10.25758/SET.1254
A. Ferrão
Introduction – The choice of treatment depends on several factors, including clinical status and prognosis of each patient. These factors play an important role in the choice of therapeutic intervention in bone metastases. Early detection and the right treatment can improve the quality of life and functional independence of patients. Methodology – This article aims to systematically review the literature of the past 15 years, identifying the different types of fractionation (single fraction versus multiple fractions) and techniques used in radiotherapy in the treatment of bone metastases. Results – Recent advances in technology and radiotherapy treatment techniques assist in the distribution of highly conformational doses and imaging guidance for a more precise delivery of treatment. The stereotactic body radiotherapy (SBRT) allows to define and increase the dose in the tumor to irradiate. In the case of bone metastasis, results from the control of local tumor and pain have proved promising. Conventional radiotherapy 8Gyx1, however, remains the preferred treatment in palliative patients. Conclusion – The treatment of bone metastasis is complex, and a multidisciplinary approach is always necessary. Treatment should be individualized to fit the symptoms and clinical status of each patient
治疗的选择取决于几个因素,包括每个病人的临床状况和预后。这些因素在骨转移的治疗干预选择中起着重要作用。早期发现和正确的治疗可以改善患者的生活质量和功能独立性。方法-本文旨在系统地回顾过去15年的文献,确定不同类型的分割(单分割与多分割)和用于骨转移治疗的放射治疗技术。结果-技术和放射治疗技术的最新进展有助于高构象剂量的分布和成像指导,以更精确地提供治疗。立体定向放射治疗(SBRT)可以确定并增加肿瘤的放射剂量。在骨转移的情况下,控制局部肿瘤和疼痛的结果证明是有希望的。然而,传统放疗仍然是姑息性患者的首选治疗方法。结论-骨转移的治疗是复杂的,需要多学科联合治疗。治疗应个体化,以适应每个病人的症状和临床状况
{"title":"O tratamento de metástases ósseas de fração única vs múltiplas frações com 3D CRT ou SBRT: artigo de revisão sistemática","authors":"A. Ferrão","doi":"10.25758/SET.1254","DOIUrl":"https://doi.org/10.25758/SET.1254","url":null,"abstract":"Introduction – The choice of treatment depends on several factors, including clinical status and prognosis of each patient. These factors play an important role in the choice of therapeutic intervention in bone metastases. Early detection and the right treatment can improve the quality of life and functional independence of patients. Methodology – This article aims to systematically review the literature of the past 15 years, identifying the different types of fractionation (single fraction versus multiple fractions) and techniques used in radiotherapy in the treatment of bone metastases. Results – Recent advances in technology and radiotherapy treatment techniques assist in the distribution of highly conformational doses and imaging guidance for a more precise delivery of treatment. The stereotactic body radiotherapy (SBRT) allows to define and increase the dose in the tumor to irradiate. In the case of bone metastasis, results from the control of local tumor and pain have proved promising. Conventional radiotherapy 8Gyx1, however, remains the preferred treatment in palliative patients. Conclusion – The treatment of bone metastasis is complex, and a multidisciplinary approach is always necessary. Treatment should be individualized to fit the symptoms and clinical status of each patient","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"36-41"},"PeriodicalIF":0.0,"publicationDate":"2016-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Validação do método de deteção de eritropoietina recombinante humana em urina humana por focalização isoelétrica 等电聚焦法检测人尿中重组红细胞生成素的方法验证
Pub Date : 2015-12-14 DOI: 10.25758/SET.1194
Ana Sofia Tavares
Erythropoietin (EPO) is a substance that stimulates red blood cell production, increasing muscle oxygenation and is secreted naturally by the body and excreted in urine in low concentrations. Due to the special properties of EPO, this was quickly introduced into the world of sport and its illicit use provides advantages in sports performance. In early 2000, was developed a method for direct detection of erythropoietin (EPO) on recombinant human urine by Lasne, based on isoelectric focusing (IEF) in polyacrylamide gel, followed by double blotting, has been published and validated. In 2002, the World Anti-Doping Agency (WADA) has implemented this same method which is currently the only official method used by laboratories accredited by WADA. The starting point for this work was the need to implement and validate the reference method, for the detection of recombinant erythropoietin in human urine. The study was conducted at the Laboratory for Doping Analysis and (LAD) of the Sports Institute of Portugal (IDP), current IPDJ. Theobjective of the work focused on validation studies/investigation of different validation parameters (specificity/selectivity; ability identification, detection limit, accuracy and repeatability), according the protocol Procedimento Geral Interno of the Antidoping Laboratory of Lisbon. This method of screening and confirmation has revealed performance characteristics in accordance with the applicable requirements for what is considered valid and fit.
促红细胞生成素(EPO)是一种刺激红细胞生成,增加肌肉氧合的物质,由身体自然分泌,低浓度随尿液排出。由于EPO的特殊性质,它很快就被引入了体育界,它的非法使用为运动表现提供了优势。2000年初,Lasne开发了一种基于聚丙烯酰胺凝胶等电聚焦(IEF),然后双印迹法直接检测重组人尿促红细胞生成素(EPO)的方法,并发表并验证。2002年,世界反兴奋剂机构(WADA)实施了同样的方法,这是目前世界反兴奋剂机构认可的实验室使用的唯一官方方法。本工作的出发点是需要实施和验证用于检测人尿中重组红细胞生成素的参考方法。这项研究是在葡萄牙体育研究所(IDP)的兴奋剂分析实验室(LAD)进行的,现在是IPDJ。工作的目的集中在不同验证参数(特异性/选择性;能力识别,检测限,准确性和可重复性),根据里斯本反兴奋剂实验室一般互联网协议程序。这种筛选和确认的方法显示了符合适用要求的性能特征,被认为是有效和合适的。
{"title":"Validação do método de deteção de eritropoietina recombinante humana em urina humana por focalização isoelétrica","authors":"Ana Sofia Tavares","doi":"10.25758/SET.1194","DOIUrl":"https://doi.org/10.25758/SET.1194","url":null,"abstract":"Erythropoietin (EPO) is a substance that stimulates red blood cell production, increasing muscle oxygenation and is secreted naturally by the body and excreted in urine in low concentrations. Due to the special properties of EPO, this was quickly introduced into the world of sport and its illicit use provides advantages in sports performance. In early 2000, was developed a method for direct detection of erythropoietin (EPO) on recombinant human urine by Lasne, based on isoelectric focusing (IEF) in polyacrylamide gel, followed by double blotting, has been published and validated. In 2002, the World Anti-Doping Agency (WADA) has implemented this same method which is currently the only official method used by laboratories accredited by WADA. The starting point for this work was the need to implement and validate the reference method, for the detection of recombinant erythropoietin in human urine. The study was conducted at the Laboratory for Doping Analysis and (LAD) of the Sports Institute of Portugal (IDP), current IPDJ. Theobjective of the work focused on validation studies/investigation of different validation parameters (specificity/selectivity; ability identification, detection limit, accuracy and repeatability), according the protocol Procedimento Geral Interno of the Antidoping Laboratory of Lisbon. This method of screening and confirmation has revealed performance characteristics in accordance with the applicable requirements for what is considered valid and fit.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"34-43"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Campos eletromagnéticos: perceção e aceitação do risco 电磁场:风险的感知和接受
Pub Date : 2015-12-14 DOI: 10.25758/set.1204
Susana Rita Silva Daniel
RESUMO: Introducao e Objetivos – Os campos eletromagneticos estao presentes naturalmente no Universo. Ha alguns anos, os valores referentes a campos eletromagneticos eram relativamente constantes. Com o desenvolvimento da tecnologia, a exposicao a novas fontes de radiacao eletromagnetica aumentou. Desta forma, e normal que a preocupacao publica, principalmente sobre os potenciais riscos para a saude provenientes dos campos eletromagneticos, tenha aumentado. O objetivo deste trabalho foi conhecer e analisar a preocupacao e a percecao dos individuos sobre a radiacao eletromagnetica, tendo por base que um dos principais fatores para a adocao de medidas de precaucao e o modo como o risco e percecionado pelo individuo. Metodologia – Trata-se de um estudo do tipo descritivo, de natureza quantitativa. A amostra, composta por 320 individuos, e de natureza nao probabilistica de conveniencia. Resultados – Verificou-se que os inquiridos se manifestam “pouco preocupados” relativamente a exposicao aos campos eletromagneticos, desconhecem as fontes emissoras de radiacao eletromagnetica presentes no seu quotidiano e nao tomam precaucoes relativamente a exposicao a campos eletromagneticos. Conclusoes – Os individuos mostram imaturidade conscienciosa em relacao a problematica da radiacao eletromagnetica, em parte justificada pela ausencia de mecanismos sensoriais que a permitam detetar. A aposta na educacao e sensibilizacao pode garantir um futuro com melhor qualidade de vida. E importante reunir esforcos de varias entidades (saude, meios de comunicacao social e educacao). A escola, atraves das criancas e jovens, constitui um meio privilegiado para a transmissao de informacao. Palavras-chave: radiacao eletromagnetica, campos eletromagneticos, percecao, exposicao, precaucao, saude humana. Electromagnetic fields: risk perception and acceptance
摘要:引言和目的——电磁场在宇宙中自然存在。几年前,电磁场的值是相对恒定的。随着技术的发展,新的电磁辐射源的暴露增加了。因此,公众对电磁场潜在健康风险的担忧增加是很自然的。本研究的目的是了解和分析个人对电磁辐射的担忧和感知,基于预防措施的主要因素之一和个人对风险的感知方式。方法:这是一项描述性的定量研究。该样本由320人组成,具有非概率性质。结果:调查发现,受访者对暴露在电磁场中“不太关心”,不知道日常生活中存在的电磁辐射源,也没有对暴露在电磁场中采取预防措施。结论:个体在电磁辐射问题上表现出有意识的不成熟,部分原因是缺乏感知电磁辐射的感觉机制。对教育和提高意识的投资可以确保未来有更好的生活质量。汇集几个实体(卫生、媒体和教育)的努力是很重要的。学校,通过儿童和年轻人,是传递信息的特权手段。关键词:电磁辐射,电磁场,穿透,暴露,预防,人体健康。电磁场:风险感知与接受
{"title":"Campos eletromagnéticos: perceção e aceitação do risco","authors":"Susana Rita Silva Daniel","doi":"10.25758/set.1204","DOIUrl":"https://doi.org/10.25758/set.1204","url":null,"abstract":"RESUMO: Introducao e Objetivos – Os campos eletromagneticos estao presentes naturalmente no Universo. Ha alguns anos, os valores referentes a campos eletromagneticos eram relativamente constantes. Com o desenvolvimento da tecnologia, a exposicao a novas fontes de radiacao eletromagnetica aumentou. Desta forma, e normal que a preocupacao publica, principalmente sobre os potenciais riscos para a saude provenientes dos campos eletromagneticos, tenha aumentado. O objetivo deste trabalho foi conhecer e analisar a preocupacao e a percecao dos individuos sobre a radiacao eletromagnetica, tendo por base que um dos principais fatores para a adocao de medidas de precaucao e o modo como o risco e percecionado pelo individuo. Metodologia – Trata-se de um estudo do tipo descritivo, de natureza quantitativa. A amostra, composta por 320 individuos, e de natureza nao probabilistica de conveniencia. Resultados – Verificou-se que os inquiridos se manifestam “pouco preocupados” relativamente a exposicao aos campos eletromagneticos, desconhecem as fontes emissoras de radiacao eletromagnetica presentes no seu quotidiano e nao tomam precaucoes relativamente a exposicao a campos eletromagneticos. Conclusoes – Os individuos mostram imaturidade conscienciosa em relacao a problematica da radiacao eletromagnetica, em parte justificada pela ausencia de mecanismos sensoriais que a permitam detetar. A aposta na educacao e sensibilizacao pode garantir um futuro com melhor qualidade de vida. E importante reunir esforcos de varias entidades (saude, meios de comunicacao social e educacao). A escola, atraves das criancas e jovens, constitui um meio privilegiado para a transmissao de informacao. Palavras-chave: radiacao eletromagnetica, campos eletromagneticos, percecao, exposicao, precaucao, saude humana. Electromagnetic fields: risk perception and acceptance","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"44-50"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influência dos métodos de correção de atenuação na quantificação da função renal relativa em cintigrafia renal com 99mTc-DMSA 衰减校正方法对99mTc-DMSA肾闪烁图相对肾功能定量的影响
Pub Date : 2015-12-14 DOI: 10.25758/SET.1154
A. Amaro, H. Silva, A. Í. Santos, E. Carolino, Tânia Vaz, L. Vieira
Introduction – The estimate of relative renal function (RRF) through scintigraphy with dimercaptosuccinic acid labelled with Technetium-99 metastable (99mTc-DMSA) may be influenced by kidney depth (KD), due to attenuation by soft tissue surrounding the kidneys. Considering that rarely this KD is known, several methods for attenuation correction (AC) have been developed, namely those using empirical formulae, such as Raynaud, Taylor or Tonnesen methods, or by direct calculation of the geometric mean (GM). Objectives – To identify the influence of different AC methods on RRF estimateby scintigraphy with 99mTc-DMSA and to evaluate the respective KD variability. Methods : Thirty-one patients were referred for 99mTc-DMSA scintigraphy and underwent the same acquisition protocol. Processing was performed by 2 independent operators, three times per exam, changing for the same processing the methods for the FRR determination: Raynaud’s method, Taylor’s method, Tonnesen´s method, GM and without AC (WAC). Friedman’s test was used to identify the influence of the different AC methods on RRF estimate and Pearson’s correlation test was used to evaluate the association and significance between KD and the variables age, weight and height. Results – Friedman’s test indicated that there were significant differences between methods (p=0.000), except for WAC/Raynaud, Tonnesen/GM and Taylor/GM (p=1.000) comparisons, for both kidneys. Pearson’s test showed a strong positive correlation between weight and the three methods of KD estimation. Conclusions – Taylor’s method, regarding the three methods of KD calculation, is the closest to GM. The choice of the attenuation correction method influences significantly the quantitative parameters of FRR.
导读-用锝-99亚稳态(99mTc-DMSA)标记的二巯基琥珀酸显像估计相对肾功能(RRF)可能受到肾脏深度(KD)的影响,因为肾脏周围软组织的衰减。考虑到很少知道这个KD,已经开发了几种衰减校正(AC)的方法,即使用经验公式的方法,如雷诺、泰勒或Tonnesen方法,或直接计算几何平均值(GM)。目的-确定不同的交流方法对99mTc-DMSA闪烁图估计的RRF的影响,并评估各自的KD变异性。方法:31例患者行99mTc-DMSA扫描,采用相同的获取方案。处理由2名独立操作员进行,每次检查3次,在相同的处理过程中改变FRR测定方法:雷诺法、泰勒法、Tonnesen法、GM法和无AC法(WAC)。采用Friedman检验确定不同AC方法对RRF估计的影响,采用Pearson相关检验评价KD与年龄、体重、身高变量的相关性及显著性。结果- Friedman试验表明,除了WAC/Raynaud、Tonnesen/GM和Taylor/GM (p=1.000)比较外,两种肾脏的方法之间存在显著差异(p=0.000)。Pearson检验显示,三种KD估计方法与权重呈正相关。结论——在三种KD计算方法中,Taylor的方法最接近GM,衰减校正方法的选择对FRR的定量参数影响较大。
{"title":"Influência dos métodos de correção de atenuação na quantificação da função renal relativa em cintigrafia renal com 99mTc-DMSA","authors":"A. Amaro, H. Silva, A. Í. Santos, E. Carolino, Tânia Vaz, L. Vieira","doi":"10.25758/SET.1154","DOIUrl":"https://doi.org/10.25758/SET.1154","url":null,"abstract":"Introduction – The estimate of relative renal function (RRF) through scintigraphy with dimercaptosuccinic acid labelled with Technetium-99 metastable (99mTc-DMSA) may be influenced by kidney depth (KD), due to attenuation by soft tissue surrounding the kidneys. Considering that rarely this KD is known, several methods for attenuation correction (AC) have been developed, namely those using empirical formulae, such as Raynaud, Taylor or Tonnesen methods, or by direct calculation of the geometric mean (GM). Objectives – To identify the influence of different AC methods on RRF estimateby scintigraphy with 99mTc-DMSA and to evaluate the respective KD variability. Methods : Thirty-one patients were referred for 99mTc-DMSA scintigraphy and underwent the same acquisition protocol. Processing was performed by 2 independent operators, three times per exam, changing for the same processing the methods for the FRR determination: Raynaud’s method, Taylor’s method, Tonnesen´s method, GM and without AC (WAC). Friedman’s test was used to identify the influence of the different AC methods on RRF estimate and Pearson’s correlation test was used to evaluate the association and significance between KD and the variables age, weight and height. Results – Friedman’s test indicated that there were significant differences between methods (p=0.000), except for WAC/Raynaud, Tonnesen/GM and Taylor/GM (p=1.000) comparisons, for both kidneys. Pearson’s test showed a strong positive correlation between weight and the three methods of KD estimation. Conclusions – Taylor’s method, regarding the three methods of KD calculation, is the closest to GM. The choice of the attenuation correction method influences significantly the quantitative parameters of FRR.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"5-12"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PET/CT com 18-fluor-fluorodeoxiglucose no seguimento do melanoma maligno cutâneo PET/CT com 18氟-氟脱氧葡萄糖无恶性黑色素瘤切面
Pub Date : 2015-12-14 DOI: 10.25758/SET.1164
S. Batanete, J. R. Infante, J. I. Rayo, L. Vieira, Escola Superior
Background – Cutaneous malignant melanoma (CMM) is one of the most lethal malignancies and the follow-up involves, in addition to clinical examination and analysis of tumor markers, several imaging methods such as the Positron Emission Tomography/Computed Tomography (PET/CT) exam with 18fluor-fluorodeoxyglucose (18F-FDG). The aim of the study is to evaluate the utility of PET/CT in the assessment of the extension of the disease and of suspected recurrence in the CMM, comparing the imaging findings with those described in CT studies. Methods – It was performed a retrospective analysis of 62 PET/CT studies in 50 patients diagnosed with CMM. It was excluded a study which had a doubtful outcome (pulmonary nodule) and it was not possible to perform its diagnosis. The information related to the results of pathologic studies and imaging studies was obtained through medical history and medical reports of CT and PET/CT. A database was created with the collected data through Excel software and a descriptive statistical analysis was carried out. Results – Of the PET/CT studies analyzed, 31 were considered true positives (TP), 28 true negatives (TN), 1 false negative (FN) and 1 false positive (FP). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of PET/CT for staging and evaluation of suspicious relapse in CMM are, respectively, 96.9%, 96.6%, 96.9%, 96.6% and 96.7%. From the CT results considered in statistical analysis, 14 corresponded to TP, 12 to TN, 3 to FP and 5 to FN. The sensitivity, specificity, PPV and NPV, and accuracy of CT for staging and evaluation of suspicious relapse in CMM are, respectively, 73.7%, 80.0%, 82.4%, 70.6% and 76.5%. Comparatively to the CT results, PET/CT allowed a change in therapeutic approach in 23% of studies. Conclusion – PET/CT is a useful tool in evaluating CMM, characterized by high diagnostic accuracy in staging and in the evaluation of suspected recurrence of MMC compared to CT only.
背景-皮肤恶性黑色素瘤(CMM)是最致命的恶性肿瘤之一,除临床检查和肿瘤标志物分析外,随访涉及几种成像方法,如正电子发射断层扫描/计算机断层扫描(PET/CT)检查18氟-氟脱氧葡萄糖(18F-FDG)。本研究的目的是评估PET/CT在评估CMM疾病扩展和疑似复发方面的效用,并将影像学结果与CT研究结果进行比较。方法:回顾性分析50例诊断为CMM的62例PET/CT研究。排除了一项结果可疑(肺结节)且无法进行诊断的研究。通过病史和CT及PET/CT的医学报告获得病理检查和影像学检查结果的相关信息。将收集到的数据通过Excel软件建立数据库,并进行描述性统计分析。结果-在分析的PET/CT研究中,31例为真阳性(TP), 28例为真阴性(TN), 1例假阴性(FN)和1例假阳性(FP)。PET/CT对CMM可疑复发分期和评估的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)和准确性分别为96.9%、96.6%、96.9%、96.6%和96.7%。从统计分析的CT结果来看,TP对应14个,TN对应12个,FP对应3个,FN对应5个。CT对CMM可疑复发分期及评价的敏感性、特异性、PPV、NPV及准确性分别为73.7%、80.0%、82.4%、70.6%、76.5%。与CT结果相比,23%的研究中PET/CT允许改变治疗方法。结论- PET/CT是评估CMM的有效工具,与CT相比,PET/CT在分期和评估MMC疑似复发方面具有较高的诊断准确性。
{"title":"PET/CT com 18-fluor-fluorodeoxiglucose no seguimento do melanoma maligno cutâneo","authors":"S. Batanete, J. R. Infante, J. I. Rayo, L. Vieira, Escola Superior","doi":"10.25758/SET.1164","DOIUrl":"https://doi.org/10.25758/SET.1164","url":null,"abstract":"Background – Cutaneous malignant melanoma (CMM) is one of the most lethal malignancies and the follow-up involves, in addition to clinical examination and analysis of tumor markers, several imaging methods such as the Positron Emission Tomography/Computed Tomography (PET/CT) exam with 18fluor-fluorodeoxyglucose (18F-FDG). The aim of the study is to evaluate the utility of PET/CT in the assessment of the extension of the disease and of suspected recurrence in the CMM, comparing the imaging findings with those described in CT studies. Methods – It was performed a retrospective analysis of 62 PET/CT studies in 50 patients diagnosed with CMM. It was excluded a study which had a doubtful outcome (pulmonary nodule) and it was not possible to perform its diagnosis. The information related to the results of pathologic studies and imaging studies was obtained through medical history and medical reports of CT and PET/CT. A database was created with the collected data through Excel software and a descriptive statistical analysis was carried out. Results – Of the PET/CT studies analyzed, 31 were considered true positives (TP), 28 true negatives (TN), 1 false negative (FN) and 1 false positive (FP). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of PET/CT for staging and evaluation of suspicious relapse in CMM are, respectively, 96.9%, 96.6%, 96.9%, 96.6% and 96.7%. From the CT results considered in statistical analysis, 14 corresponded to TP, 12 to TN, 3 to FP and 5 to FN. The sensitivity, specificity, PPV and NPV, and accuracy of CT for staging and evaluation of suspicious relapse in CMM are, respectively, 73.7%, 80.0%, 82.4%, 70.6% and 76.5%. Comparatively to the CT results, PET/CT allowed a change in therapeutic approach in 23% of studies. Conclusion – PET/CT is a useful tool in evaluating CMM, characterized by high diagnostic accuracy in staging and in the evaluation of suspected recurrence of MMC compared to CT only.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"13-20"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Ressonância Magnética e formação no Mestrado Radiações Aplicadas às Tecnologias da Saúde 磁共振成像和硕士培训辐射应用于健康技术
Pub Date : 2015-12-14 DOI: 10.25758/SET.1014
Nuno Teixeira
O Mestrado em Radiacoes Aplicadas as Tecnologias da Saude (RATeS), implementado pela Escola Superior de Tecnologia da Saude de Lisboa, ja com quatro edicoes efetivadas, e ainda hoje uma novidade singular no panorama da formacao em Portugal.
由里斯本高等卫生技术学院实施的无线电应用卫生技术(RATeS)硕士学位已经实施了四个版本,即使在今天,在葡萄牙的培训全景中仍然是一个独特的创新。
{"title":"A Ressonância Magnética e formação no Mestrado Radiações Aplicadas às Tecnologias da Saúde","authors":"Nuno Teixeira","doi":"10.25758/SET.1014","DOIUrl":"https://doi.org/10.25758/SET.1014","url":null,"abstract":"O Mestrado em Radiacoes Aplicadas as Tecnologias da Saude (RATeS), implementado pela Escola Superior de Tecnologia da Saude de Lisboa, ja com quatro edicoes efetivadas, e ainda hoje uma novidade singular no panorama da formacao em Portugal.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"37 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complicações músculo-esqueléticas crónicas nas mulheres sobreviventes de cancro da mama 乳腺癌幸存者的慢性肌肉骨骼并发症
Pub Date : 2015-12-14 DOI: 10.25758/SET.1174
Jackeline Rangel, Maria Beatriz Fernandes, E. Carolino, Escola Superior
Women diagnosed with breast cancer, have seen a significant increase in life expectancy in recent years. However, many of these women are living with chronic complications resulting from treatment. The aim of this study is to characterize musculos- keletal complications (MC) in breast cancer survivors, and emphasize the need to develop preventive therapies for these complications. Methods - Ninety four women survivors of breast cancer answered a questionnaire about potential MC. Results - The association between age and lymphedema (p=0.004), arm pain (AP) (p=0.000), shoulder pain (SP) (p=0.004), difficulty in raising the arm (DRA) ( p=0.022) and neck pain (NP) (p=0.000) sho- wed a higher incidence in women over 50 years. Women whith lymphadenectomy sho- wed higher incidence of lymphedema (p=0.000), AP (p=0.000), SP (p=0.008). Regarding survival, it was found that women over 10 years of survival have more MC. Mastectomi- zed women are more likely to have lymphedema (p=0.012), AP (p=0.020), SP (p=0.003), DRA (p=0.037) and NP. Conclusion - In our study women over 50 years, women with lymphadenectomy and with over 10 years of survival after treatment of breast cancer and
近年来,被诊断患有乳腺癌的女性的预期寿命显著延长。然而,这些妇女中有许多患有治疗引起的慢性并发症。本研究的目的是表征乳腺癌幸存者的肌肉-骨骼并发症(MC),并强调对这些并发症开发预防性治疗的必要性。结果:年龄与淋巴水肿(p=0.004)、臂痛(p=0.000)、肩痛(SP) (p=0.004)、抬臂困难(DRA) (p= 0.022)和颈痛(NP) (p=0.000)之间的关系显示,50岁以上女性的发病率较高。行淋巴结切除术的妇女淋巴水肿(p=0.000)、AP (p=0.000)、SP (p=0.008)的发生率较高。生存率方面,生存期超过10年的女性MC发生率较高,切除乳房的女性淋巴水肿(p=0.012)、AP (p=0.020)、SP (p=0.003)、DRA (p=0.037)、NP发生率较高。结论:在我们的研究中,年龄在50岁以上的女性,接受淋巴结切除术的女性,以及乳腺癌治疗后存活超过10年的女性
{"title":"Complicações músculo-esqueléticas crónicas nas mulheres sobreviventes de cancro da mama","authors":"Jackeline Rangel, Maria Beatriz Fernandes, E. Carolino, Escola Superior","doi":"10.25758/SET.1174","DOIUrl":"https://doi.org/10.25758/SET.1174","url":null,"abstract":"Women diagnosed with breast cancer, have seen a significant increase in life expectancy in recent years. However, many of these women are living with chronic complications resulting from treatment. The aim of this study is to characterize musculos- keletal complications (MC) in breast cancer survivors, and emphasize the need to develop preventive therapies for these complications. Methods - Ninety four women survivors of breast cancer answered a questionnaire about potential MC. Results - The association between age and lymphedema (p=0.004), arm pain (AP) (p=0.000), shoulder pain (SP) (p=0.004), difficulty in raising the arm (DRA) ( p=0.022) and neck pain (NP) (p=0.000) sho- wed a higher incidence in women over 50 years. Women whith lymphadenectomy sho- wed higher incidence of lymphedema (p=0.000), AP (p=0.000), SP (p=0.008). Regarding survival, it was found that women over 10 years of survival have more MC. Mastectomi- zed women are more likely to have lymphedema (p=0.012), AP (p=0.020), SP (p=0.003), DRA (p=0.037) and NP. Conclusion - In our study women over 50 years, women with lymphadenectomy and with over 10 years of survival after treatment of breast cancer and","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Programa EWASTEU: propostas para minimizar o problema dos resíduos elétricos e eletrónicos EWASTEU计划:尽量减少电力和电子废物问题的建议
Pub Date : 2015-12-14 DOI: 10.25758/SET.1144
Célio Gonçalves Marques, V. Silva
Nowadays, many of the electrical and electronic equipment we buy become obsolete in a short time because of the rapid technological advances in this field. Small and large devices such as computers, mobile phones and electronic equipment are reduced to electronic waste (e‑Waste), and many of them are disposed as common trash. To change the situation, the EU announced some directives on this subject in order to control the growth of this e‑waste and to reduce its impact. In this context, the Yasar University (Turkey) submitted to the EU a project (EWASTEU) aiming at providing an overview of what is happening with the equipment turning into e‑waste, as well as to introduce some proposals to minimise this problem. One of the main issues to be addressed will be the adequacy of the EU directives.
如今,由于这一领域的快速技术进步,我们购买的许多电气和电子设备在短时间内就过时了。计算机、移动电话和电子设备等大大小小的设备被减少为电子废物(e - waste),其中许多被作为普通垃圾处理。为了改变这种情况,欧盟宣布了一些关于这一主题的指令,以控制这种电子废物的增长并减少其影响。在此背景下,Yasar大学(土耳其)向欧盟提交了一个项目(EWASTEU),旨在概述设备转化为电子废物的情况,并提出一些建议,以尽量减少这一问题。需要解决的主要问题之一将是欧盟指令的充分性。
{"title":"Programa EWASTEU: propostas para minimizar o problema dos resíduos elétricos e eletrónicos","authors":"Célio Gonçalves Marques, V. Silva","doi":"10.25758/SET.1144","DOIUrl":"https://doi.org/10.25758/SET.1144","url":null,"abstract":"Nowadays, many of the electrical and electronic equipment we buy become obsolete in a short time because of the rapid technological advances in this field. Small and large devices such as computers, mobile phones and electronic equipment are reduced to electronic waste (e‑Waste), and many of them are disposed as common trash. To change the situation, the EU announced some directives on this subject in order to control the growth of this e‑waste and to reduce its impact. In this context, the Yasar University (Turkey) submitted to the EU a project (EWASTEU) aiming at providing an overview of what is happening with the equipment turning into e‑waste, as well as to introduce some proposals to minimise this problem. One of the main issues to be addressed will be the adequacy of the EU directives.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"41-45"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Saude Tecnologia
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1