Aims: Endoscopy is used in the diagnosis of bile reflux gastritis and Helicobacter pylori (H. pylori) gastritis. However, endoscopy is an invasive procedure with complications. The study proposes that by analyzing the absolute neutrophil - lymphocyte count ratio and mean platelet volume, it might be possible to distinguish between H. pylori gastritis and bile reflux gastritis. Methods: All patients with endoscopic and histopathological confirmation H. pylori gastritis of (Group 1), bile reflux gastritis (Group 2), or both (Group 3) were included in this retrospective study. White blood cells, absolute neutrophil count, absolute lymphocyte count and mean platelet volume were analyzed in all patients. The absolute neutrophil/lymphocyte ratio was calculated. Results: 218 patients were included in the study. The median absolute neutrophil-lymphocyte ratio was 1.33 in H. pylori gastritis, 1.56 in bile reflux gastritis, and 1.47 in both. The mean value of mean platelet volume was 9.97±0.82 in H. pylori gastritis, 10.16±0.81 in bile reflux gastritis, and 10.06±0.88 in both. The absolute neutrophil/lymphocyte ratio and mean platelet volume did not differ significantly between the groups. Conclusion: According to our results, absolute neutrophil/lymphocyte ratio cannot be used as a differential diagnosis marker in children with H. pylori gastritis and bile reflux gastritis.
{"title":"Evaluation of hematological parameters in the differentiation of bile reflux gastritis and Helicobacter pylori gastritis in children","authors":"Ezgi Kıran Taşçı","doi":"10.38053/acmj.1345970","DOIUrl":"https://doi.org/10.38053/acmj.1345970","url":null,"abstract":"Aims: Endoscopy is used in the diagnosis of bile reflux gastritis and Helicobacter pylori (H. pylori) gastritis. However, endoscopy is an invasive procedure with complications. The study proposes that by analyzing the absolute neutrophil - lymphocyte count ratio and mean platelet volume, it might be possible to distinguish between H. pylori gastritis and bile reflux gastritis. Methods: All patients with endoscopic and histopathological confirmation H. pylori gastritis of (Group 1), bile reflux gastritis (Group 2), or both (Group 3) were included in this retrospective study. White blood cells, absolute neutrophil count, absolute lymphocyte count and mean platelet volume were analyzed in all patients. The absolute neutrophil/lymphocyte ratio was calculated. Results: 218 patients were included in the study. The median absolute neutrophil-lymphocyte ratio was 1.33 in H. pylori gastritis, 1.56 in bile reflux gastritis, and 1.47 in both. The mean value of mean platelet volume was 9.97±0.82 in H. pylori gastritis, 10.16±0.81 in bile reflux gastritis, and 10.06±0.88 in both. The absolute neutrophil/lymphocyte ratio and mean platelet volume did not differ significantly between the groups. Conclusion: According to our results, absolute neutrophil/lymphocyte ratio cannot be used as a differential diagnosis marker in children with H. pylori gastritis and bile reflux gastritis.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"73 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: To investigate myopia trends and progression in urban school-aged myopic children in Turkey. Methods: This retrospective study included myopic children aged 6-18 years attending the ophthalmology clinic for regular eye and refractive examinations between 2003 and 2021. Myopia progression was calculated as the difference between the baseline and the last visit spherical equivalent refractive (SER) values. Individuals were further categorized to determine the age-specific myopia progression as 6-11, 12-16, and 17-18 age groups based on the school periods of the country. According to the SER values, individuals were classified into mild, moderate, and high myopic groups. Results: A total of 602 eyes of 301 children (191 female, 110 male) with a mean age of 11.64±2.81 (6-18) years were included in the study. The mean follow-up time of patients was 37.51±19.18 (6-98) months. The baseline mean SER value was -1.5±1.07 D (range: -0.50 and -5.62) and -2.55±1.50 at the final visit. The overall mean myopia progression was -0.35±0.37 D (range: +0.35 D and -3.75 D/year. There were 46 children between 6-11 years, 173 children between 12-16 years, 82 children between 17-18 years, and the annual SER changes were -0.46±0.40 D; -0.37±0.39 D and -0.26±0.29 D in the groups, respectively (p < 0.001). Baseline, final, and annual myopia progression were greater in females. Although there was no statistical significance, myopia progression was faster in moderate myopes (-0.39±0.33 D/a year), followed by mild (-0.35±0.37 D/a year) and high myopes (-0.21±0.20 D/a year) (p=0.37). Conclusion: The progression of myopia in school-aged Turkish children from the Western Black Sea Region is comparable to the world. Our study revealed the greater myopia progression in the youngest children, moderate myopia group, and females. Myopia prevention recommendations should be carefully advised to the youngest female ones to reduce myopia progression.
{"title":"Turkish children myopia progression in the urban area, a retrospective evaluation","authors":"P. Kaya","doi":"10.38053/acmj.1341731","DOIUrl":"https://doi.org/10.38053/acmj.1341731","url":null,"abstract":"Aims: To investigate myopia trends and progression in urban school-aged myopic children in Turkey. Methods: This retrospective study included myopic children aged 6-18 years attending the ophthalmology clinic for regular eye and refractive examinations between 2003 and 2021. Myopia progression was calculated as the difference between the baseline and the last visit spherical equivalent refractive (SER) values. Individuals were further categorized to determine the age-specific myopia progression as 6-11, 12-16, and 17-18 age groups based on the school periods of the country. According to the SER values, individuals were classified into mild, moderate, and high myopic groups. Results: A total of 602 eyes of 301 children (191 female, 110 male) with a mean age of 11.64±2.81 (6-18) years were included in the study. The mean follow-up time of patients was 37.51±19.18 (6-98) months. The baseline mean SER value was -1.5±1.07 D (range: -0.50 and -5.62) and -2.55±1.50 at the final visit. The overall mean myopia progression was -0.35±0.37 D (range: +0.35 D and -3.75 D/year. There were 46 children between 6-11 years, 173 children between 12-16 years, 82 children between 17-18 years, and the annual SER changes were -0.46±0.40 D; -0.37±0.39 D and -0.26±0.29 D in the groups, respectively (p < 0.001). Baseline, final, and annual myopia progression were greater in females. Although there was no statistical significance, myopia progression was faster in moderate myopes (-0.39±0.33 D/a year), followed by mild (-0.35±0.37 D/a year) and high myopes (-0.21±0.20 D/a year) (p=0.37). Conclusion: The progression of myopia in school-aged Turkish children from the Western Black Sea Region is comparable to the world. Our study revealed the greater myopia progression in the youngest children, moderate myopia group, and females. Myopia prevention recommendations should be carefully advised to the youngest female ones to reduce myopia progression.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"168 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: Vascularized fibula graft (VFG) technique is one of these “gold standard” techniques in bone regeneration. Although there have been several bibliometrics studies in orthopedics, there haven’t been any on VFGs. By identifying the gaps in previous research, we sought to provide light on the scientific evolution of VFGs and provide direction for future investigations. Methods: In this bibliometric study, the Web of Science (WOS) database was used to access publications on VFG published between 1986-2022. A literature search was performed with selected keywords. The dataset obtained was downloaded from the WOS database as an output. This output was analyzed with VOSviewer and Biblioshiny tools. Results: A total of 430 documents on VFG included the study. A mean of 11.9 articles/year was published on VFG. The first article on VFG published in 1986. Since 2005, there has been an increasing trend in the number of articles and citations. The year with the highest number of both publications (n=32) and citations (n=756) was 2021. The publications on VFG have cited a total of 7300 times, an average of 16.98 citations per publication. Total 51 countries contributed to publications on the VFG between 1986-2022. The United States of America (USA) was identified as the global leader in terms of the number of publications (n=91, 21.163%), followed by Japan (n=58, 13.488%) and China (n=56, 13.023%). The USA had 91 manuscripts and 2162 citations with an H-index:29 and Japan had 58 manuscripts and 1145 citations with an H-index:22. Conclusion: The literature on VFG is quite limited. Most of the publications are from developed countries. Studies should be supported for this method that can be used in the treatment of many diseases, especially in developing countries.
目的:带血管腓骨移植(VFG)技术是骨再生的“金标准”技术之一。虽然在骨科方面有一些文献计量学研究，但还没有任何关于vfg的研究。通过识别先前研究中的空白，我们试图为vfg的科学进化提供线索，并为未来的研究提供方向。方法:文献计量学研究采用Web of Science (WOS)数据库，检索1986-2022年VFG发表的文献。用选定的关键词进行文献检索。从WOS数据库下载获得的数据集作为输出。该输出用VOSviewer和Biblioshiny工具进行分析。结果:共纳入430篇VFG文献。VFG平均每年发表11.9篇文章。关于VFG的第一篇文章发表于1986年。自2005年以来，论文数量和引用次数呈上升趋势。发表数(n=32)和被引数(n=756)最多的年份是2021年。VFG上的出版物共被引7300次，平均被引16.98次。在1986年至2022年期间，共有51个国家为关于VFG的出版物作出了贡献。美国(USA)被确定为全球发表数量最多的国家(n=91, 21.163%)，其次是日本(n=58, 13.488%)和中国(n=56, 13.023%)。美国有91篇论文，2162次引用，h指数为29;日本有58篇论文，1145次引用，h指数为22。结论:关于VFG的文献相当有限。大多数出版物来自发达国家。应该支持对这种可用于治疗许多疾病的方法的研究，特别是在发展中国家。
{"title":"A bibliometric study of vascularized fibular grafting technique","authors":"S. Yılmaz","doi":"10.38053/acmj.1302810","DOIUrl":"https://doi.org/10.38053/acmj.1302810","url":null,"abstract":"Aims: Vascularized fibula graft (VFG) technique is one of these “gold standard” techniques in bone regeneration. Although there have been several bibliometrics studies in orthopedics, there haven’t been any on VFGs. By identifying the gaps in previous research, we sought to provide light on the scientific evolution of VFGs and provide direction for future investigations. \u0000Methods: In this bibliometric study, the Web of Science (WOS) database was used to access publications on VFG published between 1986-2022. A literature search was performed with selected keywords. The dataset obtained was downloaded from the WOS database as an output. This output was analyzed with VOSviewer and Biblioshiny tools. \u0000Results: A total of 430 documents on VFG included the study. A mean of 11.9 articles/year was published on VFG. The first article on VFG published in 1986. Since 2005, there has been an increasing trend in the number of articles and citations. The year with the highest number of both publications (n=32) and citations (n=756) was 2021. The publications on VFG have cited a total of 7300 times, an average of 16.98 citations per publication. Total 51 countries contributed to publications on the VFG between 1986-2022. The United States of America (USA) was identified as the global leader in terms of the number of publications (n=91, 21.163%), followed by Japan (n=58, 13.488%) and China (n=56, 13.023%). The USA had 91 manuscripts and 2162 citations with an H-index:29 and Japan had 58 manuscripts and 1145 citations with an H-index:22. \u0000Conclusion: The literature on VFG is quite limited. Most of the publications are from developed countries. Studies should be supported for this method that can be used in the treatment of many diseases, especially in developing countries.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124269754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: Interdialytic weight gain (IDWG) was shown to be associated with mortality and correlated with long-term glycemic indices in diabetic hemodialysis (DHD) patients. The aim of this study was to investigate the association between glycemic variability (GV) and IDWG in DHD patients. Methods: 82 DHD patients were studied for 6 months. Six measurements of monthly predialysis glucose were used to calculate glycemic indices. The weight gain over the dry weight of the last 10 consequent hemodialysis sessions was measured for each patient to calculate IDWG. Results: IDWG was positively correlated with GV, HbA1c (p=0.025, r=0.247 and p=0.006, r=0.304, respectively) and inversely correlated with age (p=0.01, r=-0.283). GV was positively correlated with HbA1c (p
{"title":"Impact of long-term glycemic variability on interdialytic weight gain in diabetic hemodialysis patients","authors":"M. Topal, M. Güler","doi":"10.38053/acmj.1242127","DOIUrl":"https://doi.org/10.38053/acmj.1242127","url":null,"abstract":"Aims: Interdialytic weight gain (IDWG) was shown to be associated with mortality and correlated with long-term glycemic indices in diabetic hemodialysis (DHD) patients. The aim of this study was to investigate the association between glycemic variability (GV) and IDWG in DHD patients. \u0000Methods: 82 DHD patients were studied for 6 months. Six measurements of monthly predialysis glucose were used to calculate glycemic indices. The weight gain over the dry weight of the last 10 consequent hemodialysis sessions was measured for each patient to calculate IDWG. \u0000Results: IDWG was positively correlated with GV, HbA1c (p=0.025, r=0.247 and p=0.006, r=0.304, respectively) and inversely correlated with age (p=0.01, r=-0.283). GV was positively correlated with HbA1c (p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114971177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: Infraclavicular and axillary block performed with ultrasound guidance are effective peripheral anesthesia methods applied in upper extremity surgery. We aimed to compare these methods in terms of duration of the block and action, first analgesic requirement and side effects. Methods: This prospective, randomized study was conducted for upper extremity surgery. 100 patients were included to perform infraclavicular block (Group 1, n=51) and axillary block (Group 2, n=49) USG guided. Patients are between 19 and 85 years old. Both groups were premedicated with 0.3 mg/kg midazolam or 0.5-1 μg/kg fentanyl. Both groups were treated with a mixture of local anesthetics in a total volume of 30 mL [7.5 mL 0.5% bupivacaine (Bustesin®, 56.25 mg), 7.5 mL 2% prilocaine (Priloc®, 225 mg) and 5 mL saline] was injected. Block placement time, motor and sensory tests, postoperative 2nd, 4th, 8th, 12th. and analgesic requirement at the 24th hour, Bromage scale, Verbal Rating scale, nausea vomiting, patient satisfaction, and block adequacy data were recorded. Results: In this study, 60% of the participants included were male and 40% were female. The systolic, diastolic and mean arterial pressures were higher in group of axillary blockade than those with blockade of infraclavicular blocks. Radial, median, ulnar and musculocutaneous nerve pin-prick test loss and loss of touch test was more frequent in infraclavicular block patients. According to the Bromage scale, the partial block was seen more frequently in patients who had a close block and a full block infraclavicular block. In patients with the axillary blockade, sedoanalgesia and general anesthesia needs after postoperative intraoperative 20 min and postoperative sedoanalgesia was needed. According to the postoperative Bromage scale; complete and close to the thumb and more frequent in infraclavicular block patients. In Postop VRS, it was observed that the patients with the axillary block group had mild, moderate, and severe pain complaints. Patient satisfaction in the postoperative period was similar in both groups. Conclusion: There is no significant difference between these techniques regarding surgical adequacy and subjective postoperative analgesia and dysesthesia. Complete and near-complete block rates in the infraclavicular block approach are minimally higher than in the axillary block approach.
{"title":"Comparison of infraclavicular block and axillary block activities performed in ultrasonography coexisting in upper extremity surgery","authors":"Hansa İnceöz, Zehra Baykal","doi":"10.38053/acmj.1300766","DOIUrl":"https://doi.org/10.38053/acmj.1300766","url":null,"abstract":"Aims: Infraclavicular and axillary block performed with ultrasound guidance are effective peripheral anesthesia methods applied in upper extremity surgery. We aimed to compare these methods in terms of duration of the block and action, first analgesic requirement and side effects. \u0000Methods: This prospective, randomized study was conducted for upper extremity surgery. 100 patients were included to perform infraclavicular block (Group 1, n=51) and axillary block (Group 2, n=49) USG guided. Patients are between 19 and 85 years old. Both groups were premedicated with 0.3 mg/kg midazolam or 0.5-1 μg/kg fentanyl. Both groups were treated with a mixture of local anesthetics in a total volume of 30 mL [7.5 mL 0.5% bupivacaine (Bustesin®, 56.25 mg), 7.5 mL 2% prilocaine (Priloc®, 225 mg) and 5 mL saline] was injected. Block placement time, motor and sensory tests, postoperative 2nd, 4th, 8th, 12th. and analgesic requirement at the 24th hour, Bromage scale, Verbal Rating scale, nausea vomiting, patient satisfaction, and block adequacy data were recorded. \u0000Results: In this study, 60% of the participants included were male and 40% were female. The systolic, diastolic and mean arterial pressures were higher in group of axillary blockade than those with blockade of infraclavicular blocks. Radial, median, ulnar and musculocutaneous nerve pin-prick test loss and loss of touch test was more frequent in infraclavicular block patients. According to the Bromage scale, the partial block was seen more frequently in patients who had a close block and a full block infraclavicular block. In patients with the axillary blockade, sedoanalgesia and general anesthesia needs after postoperative intraoperative 20 min and postoperative sedoanalgesia was needed. According to the postoperative Bromage scale; complete and close to the thumb and more frequent in infraclavicular block patients. In Postop VRS, it was observed that the patients with the axillary block group had mild, moderate, and severe pain complaints. Patient satisfaction in the postoperative period was similar in both groups. \u0000Conclusion: There is no significant difference between these techniques regarding surgical adequacy and subjective postoperative analgesia and dysesthesia. Complete and near-complete block rates in the infraclavicular block approach are minimally higher than in the axillary block approach.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132752281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: The objective of this retrospective study was to evaluate the prevalence of Helicobacter pylori (H. pylori) positivity, gastric atrophy, and intestinal metaplasia in patients with dyspeptic complaints who had undergone total hip and knee replacement surgeries, compared to a control group without prosthesis. Methods: The study group consisted of 51 patients with dyspeptic complaints and total knee and hip prosthesis, while the control group comprised 75 patients with similar complaints but without prosthesis. Endoscopic gastric biopsies were obtained from all participants, and the presence of H. pylori, gastric atrophy, and intestinal metaplasia were evaluated. Results: The prevalence of H. pylori positivity, gastric atrophy, and intestinal metaplasia were significantly higher in patients who underwent total knee and hip replacement compared to the control group without prosthesis. Conclusion: The results of this study suggest that patients who undergo total hip and knee replacement surgeries may be at higher risk for developing gastric pathologies, such as H. pylori infection, gastric atrophy, and intestinal metaplasia. Therefore, it is recommended that physicians who care for these patients monitor them closely for these conditions and consider endoscopic surveillance as part of their management plan.
{"title":"Increased prevalence of gastric pathologies in patients with total hip and total knee prostheses: a retrospective endoscopic study","authors":"A. Muhtaroğlu, A. Dülger","doi":"10.38053/acmj.1290478","DOIUrl":"https://doi.org/10.38053/acmj.1290478","url":null,"abstract":"Aims: The objective of this retrospective study was to evaluate the prevalence of Helicobacter pylori (H. pylori) positivity, gastric atrophy, and intestinal metaplasia in patients with dyspeptic complaints who had undergone total hip and knee replacement surgeries, compared to a control group without prosthesis. \u0000Methods: The study group consisted of 51 patients with dyspeptic complaints and total knee and hip prosthesis, while the control group comprised 75 patients with similar complaints but without prosthesis. Endoscopic gastric biopsies were obtained from all participants, and the presence of H. pylori, gastric atrophy, and intestinal metaplasia were evaluated. \u0000Results: The prevalence of H. pylori positivity, gastric atrophy, and intestinal metaplasia were significantly higher in patients who underwent total knee and hip replacement compared to the control group without prosthesis. \u0000Conclusion: The results of this study suggest that patients who undergo total hip and knee replacement surgeries may be at higher risk for developing gastric pathologies, such as H. pylori infection, gastric atrophy, and intestinal metaplasia. Therefore, it is recommended that physicians who care for these patients monitor them closely for these conditions and consider endoscopic surveillance as part of their management plan.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124346962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: It has been suggested that immuno-nutritional status may play a role in blood pressure (BP) variations. This study aimed to investigate whether prognostic nutritional index (PNI) values differ between normotensive individuals and patients with newly diagnosed untreated hypertension (NDHT) and to clarify the relationship between the PNI and circadian BP patterns in NDHT patients.
Methods: This retrospective study included 328 adult participants, comprising 164 NDHT patients and 164 normotensive individuals. The non-dipper BP pattern (NDP) was defined as a nighttime decline in BP of less than 10%. The PNI was calculated using the following formula: PNI=([10 × serum albumin (g/dL)] + [0.005 × total lymphocyte count]).
Results: The mean PNI value was lower in the NDHT group than the normotensive group (53.6±6.1 vs. 58.2±5.3, p
目的:免疫营养状况可能在血压(BP)变化中起作用。本研究旨在探讨正常血压个体与新诊断未治疗高血压(NDHT)患者预后营养指数(PNI)值是否存在差异，并阐明NDHT患者预后营养指数(PNI)与昼夜血压模式之间的关系。方法:本回顾性研究纳入328名成人受试者，包括164名NDHT患者和164名血压正常的个体。非下降血压模式(NDP)被定义为夜间血压下降小于10%。PNI的计算公式如下:PNI=([10 ×血清白蛋白(g/dL)] + [0.005 ×淋巴细胞总数])。
结果:NDHT组平均PNI值低于正常血压组(53.6±6.1 vs. 58.2±5.3,p
{"title":"The relationship between the prognostic nutritional index and non-dipping blood pressure pattern in patients with newly diagnosed hypertension","authors":"Tufan GÜNAY, Selvi COŞAR","doi":"10.38053/acmj.1258111","DOIUrl":"https://doi.org/10.38053/acmj.1258111","url":null,"abstract":"Aims: It has been suggested that immuno-nutritional status may play a role in blood pressure (BP) variations. This study aimed to investigate whether prognostic nutritional index (PNI) values differ between normotensive individuals and patients with newly diagnosed untreated hypertension (NDHT) and to clarify the relationship between the PNI and circadian BP patterns in NDHT patients.
 Methods: This retrospective study included 328 adult participants, comprising 164 NDHT patients and 164 normotensive individuals. The non-dipper BP pattern (NDP) was defined as a nighttime decline in BP of less than 10%. The PNI was calculated using the following formula: PNI=([10 × serum albumin (g/dL)] + [0.005 × total lymphocyte count]).
 Results: The mean PNI value was lower in the NDHT group than the normotensive group (53.6±6.1 vs. 58.2±5.3, p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135601504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: This study aimed to explore the incidence of osteoporosis in patients with diabetes mellitus (DM) who have been on a long-term pioglitazone regimen, and to ascertain the link between pioglitazone usage and the onset of osteoporosis. Methods: We enrolled patients prospectively and conducted a comparative analysis between two groups of DM patients: those who had been using pioglitazone for a period exceeding two years, and those with no history of pioglitazone use. Bone Mineral Density (BMD) was assessed using dual energy X-ray absorptiometry (DEXA). Results: There were no significant differences in age, gender, disease duration, fasting plasma glucose levels, and HbA1c levels between pioglitazone users and non-users. However, a significant variation was found in the BMD measurements. Patients on pioglitazone had an L1-L4 vertebra BMD T-score of -1.3, compared to -0.9 in non-users (p
{"title":"The effect of long-term use of pioglitazone on bone mineral density in patients with diabetes mellitus","authors":"M. B. Durak, Alpay Yeşi̇laltay","doi":"10.38053/acmj.1318023","DOIUrl":"https://doi.org/10.38053/acmj.1318023","url":null,"abstract":"Aims: This study aimed to explore the incidence of osteoporosis in patients with diabetes mellitus (DM) who have been on a long-term pioglitazone regimen, and to ascertain the link between pioglitazone usage and the onset of osteoporosis. \u0000Methods: We enrolled patients prospectively and conducted a comparative analysis between two groups of DM patients: those who had been using pioglitazone for a period exceeding two years, and those with no history of pioglitazone use. Bone Mineral Density (BMD) was assessed using dual energy X-ray absorptiometry (DEXA). \u0000Results: There were no significant differences in age, gender, disease duration, fasting plasma glucose levels, and HbA1c levels between pioglitazone users and non-users. However, a significant variation was found in the BMD measurements. Patients on pioglitazone had an L1-L4 vertebra BMD T-score of -1.3, compared to -0.9 in non-users (p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133292051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: Pulmonary embolism (PE) is a major contributor to the death rate associated with cardiovascular diseases. The objective of this research is to evaluate the efficacy of the PATHOS score in predicting in-hospital mortality in patients diagnosed with pulmonary embolism (PE) in emergency departments (ED). Methods: The data of patients who were visited in the ED of a third-level healthcare facility, and diagnosed with PE between 2022 and 2023 were analyzed. To examine the value of the PATHOS score in predicting mortality, through the use of Receiver Operating Characteristic (ROC) analysis, the Area Under the Curve (AUC) was determined. Results: The study was completed with 111 patients. Of these patients, 52 (46.8%) were male and 59 (53.2%) were female. The mean age of the patients was 67.67±16.49. When the cut-off value of PATHOS score in identifying in-hospital mortality was >2, the sensitivity was 70.8%, the specificity was 71.3%, and the positive predictive value was 41.2% and the negative predictive value was 81.9%. Conclusion: In this study, we concluded that the PATHOS score may be an effective tool for in-hospital mortality estimation of patients diagnosed with PE in the ED. However, this score needs further evaluation in large-scale and multicenter studies.
{"title":"A new model for estimating in-hospital mortality in patients with pulmonary embolism: PATHOS score","authors":"H. Alışkan, Mazlum Kılıç","doi":"10.38053/acmj.1306731","DOIUrl":"https://doi.org/10.38053/acmj.1306731","url":null,"abstract":"Aims: Pulmonary embolism (PE) is a major contributor to the death rate associated with cardiovascular diseases. The objective of this research is to evaluate the efficacy of the PATHOS score in predicting in-hospital mortality in patients diagnosed with pulmonary embolism (PE) in emergency departments (ED). \u0000Methods: The data of patients who were visited in the ED of a third-level healthcare facility, and diagnosed with PE between 2022 and 2023 were analyzed. To examine the value of the PATHOS score in predicting mortality, through the use of Receiver Operating Characteristic (ROC) analysis, the Area Under the Curve (AUC) was determined. \u0000Results: The study was completed with 111 patients. Of these patients, 52 (46.8%) were male and 59 (53.2%) were female. The mean age of the patients was 67.67±16.49. When the cut-off value of PATHOS score in identifying in-hospital mortality was >2, the sensitivity was 70.8%, the specificity was 71.3%, and the positive predictive value was 41.2% and the negative predictive value was 81.9%. \u0000Conclusion: In this study, we concluded that the PATHOS score may be an effective tool for in-hospital mortality estimation of patients diagnosed with PE in the ED. However, this score needs further evaluation in large-scale and multicenter studies.","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123436524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: Ultra hypofractionation using stereotactic body radiotherapy (SBRT) for low-risk PCa is considered a viable treatment option. The target volume for ultra hypofractionated RT was determined as prostate and/or proximal seminal vesicles; however, there are no clear guidelines on when to add a proximal seminal vesicle to the target volume. We aimed to dosimetrically assess the effect of inclusion of the proximal seminal vesicle in the planning target volume (PTV) on the dose distribution of organ at risk (OAR) when SBRT is administered to patients with low-risk PCa. Methods: Low-risk PCa cases who underwent SBRT with CyberKnife were retrospectively screened, and 20 random cases were included. The contours of OARs and target volumes were checked as recommended in international contouring atlases by the same radiation oncologist. Two treatment plans by determining two different PTV (prostate alone in plan 1 and prostate with proximal seminal vesicles in plan 2) were made by the same specialist physicist. 5×7.25 Gy was chosen as the dose schedule defined for both plans. Results: Regarding coverage, homogeneity index, and new conformity index (nCI), there was no significant difference between the two plans (p=0.397, p=0.452, p=0.225). The plan 2 had a greater PTV Dmax (p
{"title":"Dosimetric evaluation of inclusion of proximal seminal vesicle in target volume in low-risk prostate cancer treated with stereotactic body radiotherapy","authors":"Ela Delikgöz Soykut, Hatice Tataroglu","doi":"10.38053/acmj.1320219","DOIUrl":"https://doi.org/10.38053/acmj.1320219","url":null,"abstract":"Aims: Ultra hypofractionation using stereotactic body radiotherapy (SBRT) for low-risk PCa is considered a viable treatment option. The target volume for ultra hypofractionated RT was determined as prostate and/or proximal seminal vesicles; however, there are no clear guidelines on when to add a proximal seminal vesicle to the target volume. We aimed to dosimetrically assess the effect of inclusion of the proximal seminal vesicle in the planning target volume (PTV) on the dose distribution of organ at risk (OAR) when SBRT is administered to patients with low-risk PCa. \u0000Methods: Low-risk PCa cases who underwent SBRT with CyberKnife were retrospectively screened, and 20 random cases were included. The contours of OARs and target volumes were checked as recommended in international contouring atlases by the same radiation oncologist. Two treatment plans by determining two different PTV (prostate alone in plan 1 and prostate with proximal seminal vesicles in plan 2) were made by the same specialist physicist. 5×7.25 Gy was chosen as the dose schedule defined for both plans. \u0000Results: Regarding coverage, homogeneity index, and new conformity index (nCI), there was no significant difference between the two plans (p=0.397, p=0.452, p=0.225). The plan 2 had a greater PTV Dmax (p","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124705294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：