Pub Date : 2024-02-28DOI: 10.51253/pafmj.v74i1.11187
Mahreen Bhatti, Nabila Amin, I. Satti, Hammad Gul Khan, Abdur Rauf, Radia Tul Zahra
Objective: To compare the association of Socio-demographic factors in Polycystic Ovarian Syndrome (PCOS) patients with healthy controls. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi, Pakistan, in collaboration with Department of Gynecology and Obstetrics PEMH, Rawalpindi, Pakistan from Apr to Aug 2023. Methodology: The study comprised 300 females within reproductive age groups. Participants were separated into two groups. Group-I included 150 diagnosed PCOS patients, and Group-II had 150 healthy females selected by non-probability purposive sampling. Results: The PCOS patients exhibit a higher mean weight than the control Group (p-value; 0.017). The comparison of PCOS patients and controls showed significant association with physical activity (p-value: 0.038), hirsutism (p-value: 0.010) and Ferriman-Gallwey score (p-value: 0.001) and consanguineous marriages (p-value: 0.076). Conclusion: This study underscores the significance of socio-demographic factors in the manifestation of PCOS in Pakistan, emphasizing the need for early diagnosis, intervention, and tailored healthcare strategies, particularly among young women.
{"title":"Association of Socio-demographic factors with Polycystic Ovarian Syndrome; A Comparative Study","authors":"Mahreen Bhatti, Nabila Amin, I. Satti, Hammad Gul Khan, Abdur Rauf, Radia Tul Zahra","doi":"10.51253/pafmj.v74i1.11187","DOIUrl":"https://doi.org/10.51253/pafmj.v74i1.11187","url":null,"abstract":"Objective: To compare the association of Socio-demographic factors in Polycystic Ovarian Syndrome (PCOS) patients with healthy controls.\u0000Study Design: Comparative cross-sectional study.\u0000Place and Duration of Study: Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi, Pakistan, in collaboration with Department of Gynecology and Obstetrics PEMH, Rawalpindi, Pakistan from Apr to Aug 2023.\u0000Methodology: The study comprised 300 females within reproductive age groups. Participants were separated into two groups. Group-I included 150 diagnosed PCOS patients, and Group-II had 150 healthy females selected by non-probability purposive sampling.\u0000Results: The PCOS patients exhibit a higher mean weight than the control Group (p-value; 0.017). The comparison of PCOS patients and controls showed significant association with physical activity (p-value: 0.038), hirsutism (p-value: 0.010) and Ferriman-Gallwey score (p-value: 0.001) and consanguineous marriages (p-value: 0.076).\u0000Conclusion: This study underscores the significance of socio-demographic factors in the manifestation of PCOS in Pakistan, emphasizing the need for early diagnosis, intervention, and tailored healthcare strategies, particularly among young women.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":"262 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140420795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-28DOI: 10.51253/pafmj.v74i1.6967
Ayesha Amjad, S. B. Ayaz, Fawad Rahman, Ahmad Jamal, Naureen Tassadaq, Sonia Iqbal
Objective: To explore the association of knee pain intensity with demographics, body mass index, daily sleep hours and comorbidities in overweight people. Study Design: Cross-sectional study. Place and Duration of Study: Different Clinics of Wazirabad City, Pakistan, from Oct 2020 to May 2021. Methodology: People with knee pain for >1 month and a body mass index of ≥25 kg/m2 were included and questioned regarding variables of interest. The pain was graded according to the Numerical Rating Scale. Results: Of 335 individuals (mean age: 31±7 years), 189(56.4%) were males, and 199(59.4%) were married. The mean systolicand diastolic blood pressures were 124.4±7.9 mmHg and 85.3±7.2 mmHg, respectively. The mean sleep hours were 7±0.8 hours,while the mean body mass index was 30.1±2 kg/m2. The mean pain score was 2.8±1. Pain intensity had a significant positive correlation with age (p<0.001), body mass index (p=0.041), systolic and diastolic blood pressures (p<0.001 each). Similarly, pain intensity was significantly higher in people who were married (p<0.001) or had diabetes mellitus or hypertension (p<0.001 each). Conclusion: Knee pain intensity increases with age, body mass index, and systolic and diastolic blood pressure, and it decreases with increasing sleep hours.
{"title":"Demographics, Daily Sleep Hours, Body Mass Index, and Comorbidities in Overweight People","authors":"Ayesha Amjad, S. B. Ayaz, Fawad Rahman, Ahmad Jamal, Naureen Tassadaq, Sonia Iqbal","doi":"10.51253/pafmj.v74i1.6967","DOIUrl":"https://doi.org/10.51253/pafmj.v74i1.6967","url":null,"abstract":"Objective: To explore the association of knee pain intensity with demographics, body mass index, daily sleep hours and comorbidities in overweight people.\u0000Study Design: Cross-sectional study.\u0000Place and Duration of Study: Different Clinics of Wazirabad City, Pakistan, from Oct 2020 to May 2021.\u0000Methodology: People with knee pain for >1 month and a body mass index of ≥25 kg/m2 were included and questioned regarding variables of interest. The pain was graded according to the Numerical Rating Scale.\u0000Results: Of 335 individuals (mean age: 31±7 years), 189(56.4%) were males, and 199(59.4%) were married. The mean systolicand diastolic blood pressures were 124.4±7.9 mmHg and 85.3±7.2 mmHg, respectively. The mean sleep hours were 7±0.8 hours,while the mean body mass index was 30.1±2 kg/m2. The mean pain score was 2.8±1. Pain intensity had a significant positive correlation with age (p<0.001), body mass index (p=0.041), systolic and diastolic blood pressures (p<0.001 each). Similarly, pain intensity was significantly higher in people who were married (p<0.001) or had diabetes mellitus or hypertension (p<0.001 each).\u0000Conclusion: Knee pain intensity increases with age, body mass index, and systolic and diastolic blood pressure, and it decreases with increasing sleep hours.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":"18 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140423223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-31DOI: 10.51253/pafmj.v73i6.7466
Sara Khan, Uzma Urooj, Rabiya Khan, Nusrat Noor, Sadaf Zohra, Tooba Khan
Objective: To determine the association between hypocalcemia and pre-eclampsia. Study Design: Case-control study. Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jul 2019. Methodology: A total of 90 women, (45 with pre-eclampsia and 45 with normotensive) aged 18-40 years, were included. In all patients, 5ml of venous blood was collected and sent to an institutional pathology laboratory for serum calcium level measurement. Hypocalcemia was noted in the patients. Results: The mean gestational age in the Case-Group was 31.40±1.64 weeks, and in the Control-Group was 31.51±1.69 weeks. The mean BMI in the Case-Group was 24.94±4.39 kg/m2, and in the Control-Group was 24.24±4.61 kg/m2. The mean serum calcium levels in the Case-Group were 5328.73±2638.70 ng/ml, and in the Control-Group were 8630.03±1099.26 ng/ml. In our study, the frequency of hypocalcemia in women with pre-eclampsia (Case Group) was found to be 16(36.56%) compared to only 04(8.89%) in normotensive (Control Group) women with a p-value of 005 and Odds ratio of 5.66 which shows a positive association of hypocalcemia with pre-eclampsia. Conclusion: This study concluded that the frequency of hypocalcemia in pre-eclampsia women is very high, which shows a positive association between hypocalcemia and pre-eclampsia.
{"title":"Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia","authors":"Sara Khan, Uzma Urooj, Rabiya Khan, Nusrat Noor, Sadaf Zohra, Tooba Khan","doi":"10.51253/pafmj.v73i6.7466","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.7466","url":null,"abstract":"Objective: To determine the association between hypocalcemia and pre-eclampsia. Study Design: Case-control study. Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jul 2019. Methodology: A total of 90 women, (45 with pre-eclampsia and 45 with normotensive) aged 18-40 years, were included. In all patients, 5ml of venous blood was collected and sent to an institutional pathology laboratory for serum calcium level measurement. Hypocalcemia was noted in the patients. Results: The mean gestational age in the Case-Group was 31.40±1.64 weeks, and in the Control-Group was 31.51±1.69 weeks. The mean BMI in the Case-Group was 24.94±4.39 kg/m2, and in the Control-Group was 24.24±4.61 kg/m2. The mean serum calcium levels in the Case-Group were 5328.73±2638.70 ng/ml, and in the Control-Group were 8630.03±1099.26 ng/ml. In our study, the frequency of hypocalcemia in women with pre-eclampsia (Case Group) was found to be 16(36.56%) compared to only 04(8.89%) in normotensive (Control Group) women with a p-value of 005 and Odds ratio of 5.66 which shows a positive association of hypocalcemia with pre-eclampsia. Conclusion: This study concluded that the frequency of hypocalcemia in pre-eclampsia women is very high, which shows a positive association between hypocalcemia and pre-eclampsia.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":"87 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-30DOI: 10.51253/pafmj.v73i6.9130
Abdul Rehman Azeem Dar, Maira Aleem, Ali Akhtar, Muhammad Zahid Hussain
SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis) syndrome is a group of rare auto-inflammatory disorders with a wide range of dermatological and osteoarticular manifestations. Different nomenclatures, like Chronic Recurrent Multifocal Osteoarthritis (CRMO) and Chronic Non-Bacterial Osteomyelitis (CNO), have been used in the past for the same disease, but SAPHO Syndrome has been the accepted terminology since 1990. An adolescent, 17 years of age, with a six-month history of inflammatory backache and fatigue, reported to a rheumatology clinic. His health assessment questionnaire- disability indexcame out to be two. Acne on physical examination raised inflammatory markers, and characteristic findings of SAPHO syndrome on bone scan suggest the disease. The patient was treated with an excellent response to bisphosphonates. The report highlights the importance of the evaluation of inflammatory backache in adolescents. SAPHO syndrome is an underdiagnosed disease. Therefore, more awareness of this disease among healthcare physicians is required.
{"title":"SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis); A Case of Backache in an Adolescent in Pakistan","authors":"Abdul Rehman Azeem Dar, Maira Aleem, Ali Akhtar, Muhammad Zahid Hussain","doi":"10.51253/pafmj.v73i6.9130","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.9130","url":null,"abstract":"SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis) syndrome is a group of rare auto-inflammatory disorders with a wide range of dermatological and osteoarticular manifestations. Different nomenclatures, like Chronic Recurrent Multifocal Osteoarthritis (CRMO) and Chronic Non-Bacterial Osteomyelitis (CNO), have been used in the past for the same disease, but SAPHO Syndrome has been the accepted terminology since 1990. An adolescent, 17 years of age, with a six-month history of inflammatory backache and fatigue, reported to a rheumatology clinic. His health assessment questionnaire- disability indexcame out to be two. Acne on physical examination raised inflammatory markers, and characteristic findings of SAPHO syndrome on bone scan suggest the disease. The patient was treated with an excellent response to bisphosphonates. The report highlights the importance of the evaluation of inflammatory backache in adolescents. SAPHO syndrome is an underdiagnosed disease. Therefore, more awareness of this disease among healthcare physicians is required.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":" 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139137872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-30DOI: 10.51253/pafmj.v73i6.4525
A. Sadique, Asjad Sharif, A. Gulrez
Objectives: To compare the mean post-operative pain score with ultrasound-guided transversus abdominis plane block and wound infiltration with local anaesthetic agents in abdominal surgeries. Study design: Comparative prospective study Place and Duration of Study: Department of Anaesthesia, Intensive Care and Pain Management, Combined Military Hospital, Bahawalpur Pakistan, from Oct 2018 to Apr 2019. Methodology: Sixty patients undergoing abdominal surgery aged 18-60 years were included. The patients in Group-A received transverses abdominis plane block with 20 ml of 0.25% Bupivacaine bilaterally, while those in Group-B received 20 ml of 0.25% Bupivacaine as local wound infiltration. Each patient was followed till 6 hours post-operatively. Results: Out of 60 patients, 35(58.33%) were male, and 25(41.67%) were females. In our study, the Visual analogue score was 1.63±0.85 in Group-A (ultrasound-guided TAP block) compared with 4.47±1.07 in patients with Group-B (wound infiltration with a local anaesthetic agent) with a p-value of 0.001, which was statistically significant. Conclusion: The study concluded that the mean pain score in patients with ultrasound-guided Transversus abdominis plane block is less compared to wound infiltration with local anaesthetic agents in abdominal surgeries.
{"title":"Comparison of the Mean Post-Operative Pain Score with Ultrasound Guided Transversus Abdominis Plane (TAP) Block and Wound Infiltration with Local an Aesthetic Agent in Abdominal Surgeries","authors":"A. Sadique, Asjad Sharif, A. Gulrez","doi":"10.51253/pafmj.v73i6.4525","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.4525","url":null,"abstract":"Objectives: To compare the mean post-operative pain score with ultrasound-guided transversus abdominis plane block and wound infiltration with local anaesthetic agents in abdominal surgeries. Study design: Comparative prospective study Place and Duration of Study: Department of Anaesthesia, Intensive Care and Pain Management, Combined Military Hospital, Bahawalpur Pakistan, from Oct 2018 to Apr 2019. Methodology: Sixty patients undergoing abdominal surgery aged 18-60 years were included. The patients in Group-A received transverses abdominis plane block with 20 ml of 0.25% Bupivacaine bilaterally, while those in Group-B received 20 ml of 0.25% Bupivacaine as local wound infiltration. Each patient was followed till 6 hours post-operatively. Results: Out of 60 patients, 35(58.33%) were male, and 25(41.67%) were females. In our study, the Visual analogue score was 1.63±0.85 in Group-A (ultrasound-guided TAP block) compared with 4.47±1.07 in patients with Group-B (wound infiltration with a local anaesthetic agent) with a p-value of 0.001, which was statistically significant. Conclusion: The study concluded that the mean pain score in patients with ultrasound-guided Transversus abdominis plane block is less compared to wound infiltration with local anaesthetic agents in abdominal surgeries.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":" 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139139325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-30DOI: 10.51253/pafmj.v73i6.8277
Wahaj Ul Hassan, U. Z. Farid, Kamran Ali, Umer Naseer
Autoimmune polyglandular syndromes (APS) are rare disorders involving multiple endocrine and non-endocrine organs. These are often difficult to diagnose, as the clinical presentation of these is insidious. We present a case where a 29-year-old man presented to the Emergency Department in a state of altered sensorium with a history of focal seizures. His clinical presentation further included hypotension, malaise, and diplopia. A detailed workup revealed multiple endocrine gland involvement, and a diagnosis of APS was made.
{"title":"Autoimmune Polyglandular Syndrome Type-2 A Case Report on a Rare Disease","authors":"Wahaj Ul Hassan, U. Z. Farid, Kamran Ali, Umer Naseer","doi":"10.51253/pafmj.v73i6.8277","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.8277","url":null,"abstract":"Autoimmune polyglandular syndromes (APS) are rare disorders involving multiple endocrine and non-endocrine organs. These are often difficult to diagnose, as the clinical presentation of these is insidious. We present a case where a 29-year-old man presented to the Emergency Department in a state of altered sensorium with a history of focal seizures. His clinical presentation further included hypotension, malaise, and diplopia. A detailed workup revealed multiple endocrine gland involvement, and a diagnosis of APS was made.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":" March","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139136990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To find out the utilization of C-reactive protein (CRP), Procalcitonin (PCT) and red cell distribution width (RDW) in diagnosing neonatal sepsis considering blood culture findings as gold standard. Study Design: Cross-sectional validation study. Place and Duration of Study: Neonatal Intensive Care Unit (NICU) of Dr Ziauddin Medical University, Karachi Pakistan, from Feb to Jul 2022. Methodology: A total of 42 neonates of either gender with the clinical diagnosis of neonatal sepsis were enrolled. Demographical and clinical characteristics of all neonates were noted at the time of enrollment. A blood sample of 5 ml was withdrawn for the evaluation of CRP, PCT and RDS. The association of different inflammatory markers with the outcome (neonatal sepsis) was assessed. Results: In 42 neonates, the mean age was 7.24±9.24 days, and 26 (61.9%) neonates were boys. Respiratory distress, reluctance to feed and hypoglycemia were the most frequent clinical presentations observed (19,45.2%), (14,33.3%) and (8,19.0%) neonates, respectively. Mean CRP levels among blood culture positive and negative neonates were 40.02±57.84mg/dl and 7.57±13.34 mg/dl, respectively, while the difference was statistically significant (p=0.0068). RDW (p=0.6488) and procalcitonin (0.9021) levels were not statistically significant differences among positive and negative neonates of blood culture. Conclusion: The CRP was a significant predictor of neonatal sepsis, while RDW and procalcitonin did not have a significant relationship with early prediction of neonatal sepsis.
{"title":"Role of Inflammatory Markers in Early Diagnosis of Neonatal Sepsis; C-Reactive Protein or Procalcitonin or Red Cell Distribution Width; A Hospital-Based Study","authors":"Prinka Bai, Heena Rais, Rabia Asif, Tayyaba Anwar, Sandhiya Kumari, Masab Azeem","doi":"10.51253/pafmj.v73i6.9349","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.9349","url":null,"abstract":"Objective: To find out the utilization of C-reactive protein (CRP), Procalcitonin (PCT) and red cell distribution width (RDW) in diagnosing neonatal sepsis considering blood culture findings as gold standard. Study Design: Cross-sectional validation study. Place and Duration of Study: Neonatal Intensive Care Unit (NICU) of Dr Ziauddin Medical University, Karachi Pakistan, from Feb to Jul 2022. Methodology: A total of 42 neonates of either gender with the clinical diagnosis of neonatal sepsis were enrolled. Demographical and clinical characteristics of all neonates were noted at the time of enrollment. A blood sample of 5 ml was withdrawn for the evaluation of CRP, PCT and RDS. The association of different inflammatory markers with the outcome (neonatal sepsis) was assessed. Results: In 42 neonates, the mean age was 7.24±9.24 days, and 26 (61.9%) neonates were boys. Respiratory distress, reluctance to feed and hypoglycemia were the most frequent clinical presentations observed (19,45.2%), (14,33.3%) and (8,19.0%) neonates, respectively. Mean CRP levels among blood culture positive and negative neonates were 40.02±57.84mg/dl and 7.57±13.34 mg/dl, respectively, while the difference was statistically significant (p=0.0068). RDW (p=0.6488) and procalcitonin (0.9021) levels were not statistically significant differences among positive and negative neonates of blood culture. Conclusion: The CRP was a significant predictor of neonatal sepsis, while RDW and procalcitonin did not have a significant relationship with early prediction of neonatal sepsis.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139137238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-30DOI: 10.51253/pafmj.v73i6.6345
Chaudhry Raheel Ranjha, Muhammad Saeed, Basit Mehmood, Umer Hayat, Sana Abbas, Arona Terrence
Objective: To compare the efficacy of Dexmedetomidine with Tramadol for shivering post-spinal anaesthesia. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Anaesthesia, Combined Military Hospital, Rawalpindi Pakistan, from Jul to Dec 2020. Methodology: A total of 158 patients who underwent gynaecological, orthopaedic and general surgical procedures under spinal anaesthesia using 0.5% hyperbaric Bupivacaine 12-15 mg were included in the study. Out of these 158 patients, 64% (102 patients) developed shivering after spinal anaesthesia. These 102 patients were divided into two equal groups, i.e., Group-D (n=51), who received 0.5 μg/kg Dexmedetomidine and Group-T (n=51), who received 0.5 mg/kg tramadol. The response in the next 15 mins was evaluated objectively as “effective” or “non-effective” by the treating Anesthesiologist. Results: Dexmedetomidine and Tramadol were effective in treating shivering following spinal anaesthesia. Our study showed that Dexmedetomidine was more effective than Tramadol in treating shivering, with an effectiveness of 88.2 % shivering relief in Group-D and an effectiveness of 51 % shivering relief in Group-T. The effectiveness was significant in both groups, with statistical significance in Group-D compared to Group-T (p<0.05). Conclusion: Shivering relief was more responsive in patients who received Dexmedetomidine than Tramadol after spinal anaesthesia.
{"title":"Comparison of Dexmedetomidine with Tramadol for Treatment of Shivering Post Spinal Anaesthesia","authors":"Chaudhry Raheel Ranjha, Muhammad Saeed, Basit Mehmood, Umer Hayat, Sana Abbas, Arona Terrence","doi":"10.51253/pafmj.v73i6.6345","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.6345","url":null,"abstract":"Objective: To compare the efficacy of Dexmedetomidine with Tramadol for shivering post-spinal anaesthesia. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Anaesthesia, Combined Military Hospital, Rawalpindi Pakistan, from Jul to Dec 2020. Methodology: A total of 158 patients who underwent gynaecological, orthopaedic and general surgical procedures under spinal anaesthesia using 0.5% hyperbaric Bupivacaine 12-15 mg were included in the study. Out of these 158 patients, 64% (102 patients) developed shivering after spinal anaesthesia. These 102 patients were divided into two equal groups, i.e., Group-D (n=51), who received 0.5 μg/kg Dexmedetomidine and Group-T (n=51), who received 0.5 mg/kg tramadol. The response in the next 15 mins was evaluated objectively as “effective” or “non-effective” by the treating Anesthesiologist. Results: Dexmedetomidine and Tramadol were effective in treating shivering following spinal anaesthesia. Our study showed that Dexmedetomidine was more effective than Tramadol in treating shivering, with an effectiveness of 88.2 % shivering relief in Group-D and an effectiveness of 51 % shivering relief in Group-T. The effectiveness was significant in both groups, with statistical significance in Group-D compared to Group-T (p<0.05). Conclusion: Shivering relief was more responsive in patients who received Dexmedetomidine than Tramadol after spinal anaesthesia.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139140093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-30DOI: 10.51253/pafmj.v73i6.8963
Nighat Bakhtiar, O. Shakeel, Saleema Begum, Syed Irfan Kabir, A. Syed
Objective: To review the initial experience of outcomes of a consecutive series of laparoscopic distal pancreatic resections are performed at a dedicated cancer hospital. Study Design: Case series. Place and Duration of Study: Department of Surgical Oncology at Tertiary Care Hospital, from Mar 2013 to Feb 2021. Methodology: A retrospective review of consecutive series of patients in which distal laparoscopic pancreatic resections were performed. Data was collected through the Hospital information system (HIS), an electronic hospital database. All patients were discussed in a multidisciplinary team prior to surgery. Results: Fifteen patients, including 4(26.6%) males with a mean age of 49.27±15.2, were planned for laparoscopic distal pancreatectomy. Pathologically, 12(80%) tumours were malignant, while three were benign. The procedure was converted to open in 3 patients. The mean operating time was 4.6±0.57 hours, with an estimated blood loss of around 183±28. 8mls.Mean hospital stay was 5.3±1.5 days. One patient developed a Grade A pancreatic fistula. Recurrence in the liver occurred in two patients, which was managed by systemic adjuvant therapy. However, one of them died later on because of sepsis. Conclusion: A laparoscopic distal pancreatectomy is a safe approach for distal pancreatic tumours, with minimal complications and fast recovery in appropriate cases.
{"title":"Initial Experience of Laparoscopic Distal Pancreatic Resections: A Single Institution Study with Fifteen Consecutive Cases","authors":"Nighat Bakhtiar, O. Shakeel, Saleema Begum, Syed Irfan Kabir, A. Syed","doi":"10.51253/pafmj.v73i6.8963","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.8963","url":null,"abstract":"Objective: To review the initial experience of outcomes of a consecutive series of laparoscopic distal pancreatic resections are performed at a dedicated cancer hospital. Study Design: Case series. Place and Duration of Study: Department of Surgical Oncology at Tertiary Care Hospital, from Mar 2013 to Feb 2021. Methodology: A retrospective review of consecutive series of patients in which distal laparoscopic pancreatic resections were performed. Data was collected through the Hospital information system (HIS), an electronic hospital database. All patients were discussed in a multidisciplinary team prior to surgery. Results: Fifteen patients, including 4(26.6%) males with a mean age of 49.27±15.2, were planned for laparoscopic distal pancreatectomy. Pathologically, 12(80%) tumours were malignant, while three were benign. The procedure was converted to open in 3 patients. The mean operating time was 4.6±0.57 hours, with an estimated blood loss of around 183±28. 8mls.Mean hospital stay was 5.3±1.5 days. One patient developed a Grade A pancreatic fistula. Recurrence in the liver occurred in two patients, which was managed by systemic adjuvant therapy. However, one of them died later on because of sepsis. Conclusion: A laparoscopic distal pancreatectomy is a safe approach for distal pancreatic tumours, with minimal complications and fast recovery in appropriate cases.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":" 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139140351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: To evaluate the frequency, risk factors and mortality of post-banding bleeding in cirrhosis. Study Design: Retrospective longitudinal Study. Place and Duration of Study: Department of Medicine, Fauji Foundation Hospital, Rawalpindi Pakistan, from Feb to Jul 2021. Methodology: Esophageal variceal band ligation (EVBL) was done in 123 patients. The study cohort was divided into two groups: Group-1 without re-bleed and Group-2 with re-bleed. Blood chemistry, Child-Pugh and MELD score, including the indications of EVBL and risk factors, were also analysed. Regression analysis was performed. Results: Re-bleed occurred in 10.6% (n=13) of patients. The mean duration between ligation and re-bleed was 8.75±2.8 days. Oesophageal ulcers were the most common cause of re-bleeding (38.5%). Mortality rates among the two groups were 21.8 %( n=24) and 30.8 %( n=4), respectively. The model for end-stage liver disease score (OR 2.177, CI 1.069-4.43, p .03), APTT (OR 0.593, CI 0.397-0.887, p .01) and Sodium (OR 1.345, CI 1.07-1.69, p<0.01) were detected as the predictors of re-bleed. Conclusion: Although re-bleeding after banding occurs in a trivial number of patients, it contributes to mortality. Coagulopathy, high sodium and MELD score are major predictors.
{"title":"Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis","authors":"Shahida Perveen, Omar Ahsan, Batool Butt, Atif Abbas, S. Asif, Syeda Fatima Hassan","doi":"10.51253/pafmj.v73i6.8835","DOIUrl":"https://doi.org/10.51253/pafmj.v73i6.8835","url":null,"abstract":"Objectives: To evaluate the frequency, risk factors and mortality of post-banding bleeding in cirrhosis. Study Design: Retrospective longitudinal Study. Place and Duration of Study: Department of Medicine, Fauji Foundation Hospital, Rawalpindi Pakistan, from Feb to Jul 2021. Methodology: Esophageal variceal band ligation (EVBL) was done in 123 patients. The study cohort was divided into two groups: Group-1 without re-bleed and Group-2 with re-bleed. Blood chemistry, Child-Pugh and MELD score, including the indications of EVBL and risk factors, were also analysed. Regression analysis was performed. Results: Re-bleed occurred in 10.6% (n=13) of patients. The mean duration between ligation and re-bleed was 8.75±2.8 days. Oesophageal ulcers were the most common cause of re-bleeding (38.5%). Mortality rates among the two groups were 21.8 %( n=24) and 30.8 %( n=4), respectively. The model for end-stage liver disease score (OR 2.177, CI 1.069-4.43, p .03), APTT (OR 0.593, CI 0.397-0.887, p .01) and Sodium (OR 1.345, CI 1.07-1.69, p<0.01) were detected as the predictors of re-bleed. Conclusion: Although re-bleeding after banding occurs in a trivial number of patients, it contributes to mortality. Coagulopathy, high sodium and MELD score are major predictors.","PeriodicalId":31059,"journal":{"name":"Pakistan Armed Forces Medical Journal","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139140443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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