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Eurasian Journal of Medical Investigation最新文献

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The Radiotherapy Adherence of Patients in Time of COVID-19 Pandemic COVID-19大流行时期患者放疗依从性分析
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2022.51946
F. Tugrul
as space, equipment, and personnel. The present study tried to assess how the fear of hospitals and the pandemic measures affected the radiotherapy course of patients. Methods: The records of patients receiving active cancer therapy in the department of radiation oncology were retrospectively analyzed. Treatment delays before and after March 11, 2020, were recorded. Results: None of the 80 patients (0%) failed to complete radiotherapy before March 11, 2020, while 5 of 55 patients (9.1%) had radiotherapy cessation after the first COVID-19 case and the following restrictions in Turkey (p<0.01). There was no difference in treatment type between the groups; no difference between palliative and curative subgroups before and after the pandemic (p=0.22). There was no difference in overall survival between pre- and post-COVID-19 periods (p=0.35). Conclusion: However, some patients may not receive adequate diagnostic procedures during this period. The regulations to prevent the spread of the COVID-19 may harm specific patient populations such as radiotherapy patients. The non-specific rules and declarations confuse the patients and prevent them from accessing the treatment needed. In the case of pandemic regulations, government decisions may include special considerations for oncological patients. Abstract Cite This Article: Tugrul F, Beypinar I. The Radiotherapy Adherence of Patients in Time of COVID-19 Pandemic. EJMI 2022;6(4):512–516.
如空间、设备和人员。本研究试图评估对医院和流行病措施的恐惧如何影响患者的放射治疗过程。方法:回顾性分析放射肿瘤科接受肿瘤积极治疗的患者资料。记录了2020年3月11日前后的治疗延误情况。结果:80例患者(0%)在2020年3月11日前均未完成放疗,而土耳其55例患者中有5例(9.1%)在第一例COVID-19病例及以下限制后停止放疗(p<0.01)。两组间治疗方式无差异;大流行前后姑息治疗亚组和治疗亚组之间无差异(p=0.22)。covid -19前后的总生存率无差异(p=0.35)。结论:然而,一些患者在此期间可能没有得到充分的诊断程序。防止COVID-19传播的规定可能会损害特定患者群体,如放疗患者。不具体的规则和声明使患者感到困惑,并阻止他们获得所需的治疗。就大流行法规而言,政府的决定可能包括对肿瘤患者的特殊考虑。[摘要]引用本文:Tugrul F, Beypinar I. COVID-19大流行时期患者放疗依从性的研究。EJMI 2022; 6(4): 512 - 516。
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引用次数: 0
Lifestyle behaviour after diagnosis of cancer 诊断癌症后的生活方式行为
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2021.24427
B. Oven
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引用次数: 1
Chemotherapy Choice in Neoadjuvant Dual Her2 Blockade: Is it Really Essential to Add Anthracycline? 新辅助双重Her2阻断的化疗选择:是否真的需要添加蒽环类药物?
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2023.59897
A. Ozveren
Objectives: Addition of trastuzumab and pertuzumab to neoadjuvant chemotherapy in Human epidermal growth factor receptor 2 (HER-2) positive breast cancer is the current clinical standard. We aimed to determine whether anthra-cycline-containing neoadjuvant chemotherapy yields beneficial effects alongside dual HER-2 blockade, and to assess cardiotoxicity with this treatment. Methods: Fifty-two patients with HER-2-positive breast cancer who received neoadjuvant chemotherapy were retrospectively evaluated at three tertiary health-care centers. The effects of chemotherapy regimen and several other factors such as age, stage, menopause status, lymph node positivity, and hormone receptor positivity on pathological complete response (pCR) were evaluated. Results: The mean age at diagnosis was 46±9 years. The pCR rate was similar between those with and without anthra-cycline-containing regimens (71.4% vs. 70%). Subgroup analyses also showed similar pCR values for those with negative and positive hormone receptors (64.7% vs. 74.3%), those with Ki67 levels <20% and >20% (60% vs. 73.8%), and when premenopausal patients were compared with postmenopausal patients (76.9% vs. 65.4%). Conclusion: It appears that adding anthracycline to dual HER-2 blockade for neoadjuvant therapy did not yield additional benefits in terms of pCR. Further studies are needed to assess anthracycline-containing regimens in patients who will use the neoadjuvant pertuzumab-trastuzumab combination.
目的:在人表皮生长因子受体2 (HER-2)阳性乳腺癌的新辅助化疗中加入曲妥珠单抗和帕妥珠单抗是目前的临床标准。我们的目的是确定含炭疽环素的新辅助化疗是否在双重HER-2阻断的情况下产生有益的效果,并评估这种治疗的心脏毒性。方法:回顾性分析3个三级保健中心的52例her -2阳性乳腺癌患者接受新辅助化疗的情况。评估化疗方案和其他因素(如年龄、分期、绝经状态、淋巴结阳性、激素受体阳性)对病理完全反应(pCR)的影响。结果:平均诊断年龄为46±9岁。采用和不采用含炭疽周期素方案的患者的pCR率相似(71.4%对70%)。亚组分析也显示,激素受体阴性和阳性患者的pCR值相似(64.7%对74.3%),Ki67水平为20%(60%对73.8%),绝经前患者与绝经后患者的pCR值相似(76.9%对65.4%)。结论:在新辅助治疗中,在HER-2双重阻断的基础上加入蒽环类药物似乎并没有产生额外的pCR益处。需要进一步的研究来评估将使用新辅助帕妥珠单抗-曲妥珠单抗联合治疗的患者的含蒽环类药物方案。
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引用次数: 0
Relationship Between Glucose-To-Lymphocyte, Albumin-To Alkaline Phosphatase and Neutrophil-To-Lymphocyte Rat and Prognosis in Young Patients with Pancreatic Cancer 年轻胰腺癌患者糖转淋巴细胞、白蛋白转碱性磷酸酶和中性粒细胞转淋巴细胞与预后的关系
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2023.86631
E. Kut
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引用次数: 0
Addiction in Adolescents During COVID-19 Pandemic: A Systematic Review COVID-19大流行期间青少年成瘾:一项系统综述
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2021.28744
M. Gul
spend their time at home, physical activity, social life and social interaction have been severely restricted. Fear of illness, losing a close person, limitation of interaction with peers, changes in eating habits and sleep patterns, etc. affected children and adolescents as well as adults and uncertainty of the period have caused an increase in psychological and social problems in this age group. Especially the school closures, maintaining education with online distance education both have decreased the efficiency in education and caused children and adolescents to spend most of their time in the internet. Internet has not been used only for school and lessons, also using for entertainment have caused prolonged exposure to screens. As well as behavioral addictions, substance use in order to cope with difficulties has become a worthy subject to investigate in this period. It is predicted that the ongoing pandemic process will accelerate the studies about addictions in adolescents. In this review, we aimed to take attention to studies on addiction in adolescents during the COVID-19 pandemic. Abstract Cite This Article: Gul MK, Demirci E. Addiction in Adolescents During COVID-19 Pandemic: A Systematic Review. EJMI 2022;6(3):267–272.
他们在家里度过的时间,身体活动、社交生活和社会交往都受到了严重限制。对疾病的恐惧、失去亲密的人、与同伴交往的限制、饮食习惯和睡眠模式的改变等影响到儿童和青少年以及成年人,以及时期的不确定性导致了这一年龄组心理和社会问题的增加。特别是学校关闭,以在线远程教育维持教育,既降低了教育效率,又导致儿童和青少年将大部分时间花在互联网上。互联网不仅用于上学和上课,也用于娱乐,导致长时间暴露在屏幕前。与行为成瘾一样,为了应对困难而使用物质也成为这一时期值得研究的课题。据预测,目前的流行病进程将加速对青少年成瘾的研究。在这篇综述中,我们旨在关注COVID-19大流行期间青少年成瘾的研究。Gul MK, Demirci E.。COVID-19大流行期间青少年成瘾:一项系统综述。EJMI 2022; 6(3): 267 - 272。
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引用次数: 1
Could ARNI have an Effect on LV Fibrosis and Inflammatory Parameters in an Experimental Autoimmune Myocarditis Model? ARNI对实验性自身免疫性心肌炎模型左室纤维化和炎症参数有影响吗?
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2022.80484
Ali Duygu
,
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引用次数: 1
The Relationship Between the Prognostic Nutritional Index and Overall Survival in Elderly Patients with Epithelial Ovarian Cancer 老年上皮性卵巢癌患者预后营养指数与总生存率的关系
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2020.30288
A. Demir, O. Alan, S. Koca, H. Surmeli
DOI: 10.14744/ejmi.2020.30288 EJMI 2020;4(2):269–273
DOI: 10.14744/ejmi.2020.30288 EJMI 2020;4(2):269-273
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引用次数: 4
The Impacts of Radical Gynecologic Surgery and Radiotherapy on Lower Urinary Tract of Patients with Cervix and Uterine Cancer 妇科根治性手术及放疗对子宫颈癌患者下尿路的影响
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2021.32395
H. Gurer
DOI: 10.14744/ejmi.2021.32395 EJMI 2021;5(2):240–245
DOI: 10.14744/ejmi.2021.32395 EJMI 2021;5(2):240-245
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引用次数: 0
Anatomical Variations in Foramen Transversarium 横截孔的解剖变异
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2019.15468
Mahinur Ulusoy
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引用次数: 0
Treatment of active acne by a novel high-power diode laser at 1060 nm: A case report 新型1060nm高功率二极管激光器治疗活动性痤疮1例
Pub Date : 1900-01-01 DOI: 10.14744/ejmi.2019.40300
Gabriel Buendía Bordera
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引用次数: 1
期刊
Eurasian Journal of Medical Investigation
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