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High-Intensity Focused Ultrasound Scattering at Mammal Vertebrae 哺乳动物椎骨的高强度聚焦超声散射
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-24676
D. Sanford, C. Schaal
High-intensity focused ultrasound (HIFU) is used clinically to heat cells therapeutically or to destroy them through heat or cavitation. In homogeneous media, the highest wave amplitudes occur at a predictable focal region. However, HIFU is generally not used in the proximity of bones due to wave absorption and scattering. Ultrasound is passed through the skull in some clinical trials, but the complex geometry of the spine poses a greater targeting challenge and currently prohibits therapeutic ultrasound treatments near the vertebral column. This paper presents a comprehensive experimental study involving shadowgraphy and hydrophone measurements to determine the spatial distribution of pressure amplitudes from induced HIFU waves near vertebrae. First, a bone-like composite plate that is partially obstructing the induced waves is shown to break the conical HIFU form into two regions. Wave images are captured using pulsed laser shadowgraphy, and hydrophone measurements over the same region are compared to the shadowgraphy intensity plots to validate the procedure. Next, shadowgraphy is performed for an individual, clean, ex-vivo feline vertebra. The results indicate that shadowgraphy can be used to determine energy deposition patterns and to determine heating at a specific location. The latter is confirmed through additional temperature measurements. Overall, these laboratory experiments may help determine the efficacy of warming specific nerve cells within mammal vertebrae without causing damage to adjacent tissue.
高强度聚焦超声(HIFU)在临床上用于加热细胞或通过加热或空化来破坏细胞。在均匀介质中,最高的波幅出现在可预测的震源区域。然而,由于波的吸收和散射,HIFU通常不用于靠近骨骼的地方。在一些临床试验中,超声是通过颅骨进行的,但脊柱的复杂几何形状带来了更大的靶向挑战,目前禁止在脊柱附近进行治疗性超声治疗。本文介绍了一项综合实验研究,包括阴影成像和水听器测量,以确定椎骨附近诱导HIFU波的压力振幅的空间分布。首先,骨样复合板部分阻挡诱导波,将HIFU的锥形形态分成两个区域。使用脉冲激光阴影成像捕获波浪图像,并将同一区域的水听器测量结果与阴影成像强度图进行比较,以验证该程序。接下来,对一个单独的、干净的、离体的猫椎骨进行阴影成像。结果表明,阴影法可以用于确定能量沉积模式和确定特定位置的加热。后者通过额外的温度测量得到证实。总的来说,这些实验室实验可能有助于确定加热哺乳动物椎骨内特定神经细胞的功效,而不会对邻近组织造成损害。
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引用次数: 1
The Condition of Dynamic Stability for Self-Paced Treadmill Walking Based on Inverted Pendulum Model 基于倒立摆模型的自定速跑步机行走动态稳定性条件研究
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-23461
Yuyang Qian, Kaiming Yang, Yu Zhu, Wen Wang, C. Wan
A self-paced treadmill automatically adjusts speed in real-time to match the user’s walking speed, presumably leading to a more nature gait than fixed-speed treadmill. However, previous study has proven that the acceleration applied to the subjects would influence the gait stability. In order to have insights on to which extent will the accelerations affect gait stability, simulation analysis based on conceptual model has been done in the current study. This paper utilized a non-inertial frame based spring-loaded inverted pendulum model to analysis the condition of stability during continuous self-paced treadmill walking. Simulations were done for 100 continuous self-paced treadmill walking at the normal walking speed. And 10ms impulse accelerations of different magnitudes with the range of (−1g, 1g) were applied at different gait events such as toe-off, foot-flat and heel-strike. The simulation results showed that the magnitude of the accelerations had significantly influence on continuous self-paced treadmill walking and directional-dependency was also found. However, no significantly difference was found when applying the impulse acceleration at different gait events.
自定速跑步机会自动实时调整速度,以匹配用户的行走速度,这可能会比固定速度跑步机更自然。然而,先前的研究已经证明,施加在受试者身上的加速度会影响步态的稳定性。为了了解加速度对步态稳定性的影响程度,本研究基于概念模型进行了仿真分析。本文采用基于非惯性系的弹簧倒立摆模型,分析了自定速跑步机连续行走时的稳定性条件。在正常步行速度下,对100个连续的自定步跑步机进行了模拟。在脱趾、平足和撞跟等不同步态事件中施加10ms不同量级的脉冲加速度,范围为(- 1g, 1g)。仿真结果表明,加速度的大小对跑步机连续自定步行走有显著影响,并且存在方向依赖性。然而,在不同的步态事件中施加脉冲加速度时,没有发现显著差异。
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引用次数: 0
Initial Study Towards the Integrated Design of Bone Scaffolds Based on Cell Diffusion, Growth Factor Release and Tissue Regeneration 基于细胞扩散、生长因子释放和组织再生的骨支架一体化设计初步研究
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-23940
M. Şahin, A. Tabak, Gullu Kiziltas Sendur
Three-dimensional (3D) porous tissue scaffolds combined with bioactive molecules and cells offer key advantages for bone repair mechanisms. A functional bone tissue scaffold should provide mechanical support with an adequate combination of porosity and permeability for nutrients, oxygen supply, waste removal, and growth factors release as well as controlled degradation. Although a vast amount of work exist to address these challenges, to the best of our knowledge, a design framework taking tissue differentiation, diffusion, and growth factor (GF) release into account in time-domain simultaneously does not exist. In this paper, we provide an initial effort to address such a need by laying down the foundations for a simulation framework incorporating these effects within a Finite Element Analysis (FEA) model in COMSOL Multiphysics® software. The effectiveness of the numerical model is demonstrated via preliminary mechano-biology analyses on a simulated 3D poroelastic bone scaffold. Initial time-dependent results demonstrate the suitability of this model for an optimization framework. More specifically, it is demonstrated that coupled Multiphysics equations of diffusion, GF release, and differentiation could provide valuable inputs for ideal bone scaffold systems for effective bone repair tasks in the future.
结合生物活性分子和细胞的三维多孔组织支架为骨修复机制提供了关键优势。一个功能性的骨组织支架应该提供机械支持,并具有足够的孔隙度和渗透性,以供营养、供氧、清除废物、释放生长因子以及控制降解。尽管存在大量的工作来解决这些挑战,但据我们所知,在时域内同时考虑组织分化、扩散和生长因子(GF)释放的设计框架尚不存在。在本文中,我们通过为COMSOL Multiphysics®软件中的有限元分析(FEA)模型中包含这些效果的仿真框架奠定基础,提供了解决此类需求的初步努力。通过模拟三维多孔弹性骨支架的初步力学生物学分析,证明了数值模型的有效性。初始的时间相关结果证明了该模型对于优化框架的适用性。更具体地说,研究表明,扩散、GF释放和分化的耦合多物理场方程可以为未来有效骨修复任务的理想骨支架系统提供有价值的输入。
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引用次数: 1
Manufacturing Capability Index of 3D Printing Parts for Impact Applications 用于冲击应用的3D打印部件制造能力指数
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-23123
A. Schmitz
Three-dimensional (3D) printing with high-resolution stereolithography (SLA) has grown in popularity for creating personalized medical devices. 3D printing is now starting to expand to weight-bearing components, e.g. prosthetic feet, as data on the dynamic properties impact and fatigue is published in the literature. The next step towards using 3D printing in impact applications is to assess the capability of the high-resolution SLA process to manufacture components of uniform impact resistance. Because impact testing is destructive, a surrogate measure to check a part’s viability for resisting an impact load also needs to be established. Thirteen notched Izod specimens were printed on a Form2 SLA printer using the manufacturer’s clear V4, photocurable resin. Once all the specimens were printed, washed in isopropyl alcohol, and cured with ultraviolet light, the impact resistance was quantified using a pendulum impact tester in a notched Izod configuration. Then, the hardness of the specimens was quantified using a HBW 10/250 scale. The impact resistance of the clear, SLA polymer was 0.59 ± 0.14 ft-lb/in. With an upper standard limit of 0.53 ft-lb/in, the process capability index was 0.133. Impact resistance and Brinell hardness were not correlated with a Spearman coefficient of r = −0.108, p = 0.73. Since the process capability index was less than one, 3D printing with SLA polymers is not a viable manufacturing process for creating parts of consistent impact resistance. The current technology would lead to too many rejected parts. Also, Brinell hardness and impact strength were not related. Therefore, there is no non-destructive method to spot-check these components before use.
高分辨率立体光刻(SLA)的三维(3D)打印在创建个性化医疗设备方面越来越受欢迎。3D打印现在开始扩展到承重部件,例如假肢脚,因为有关动态特性影响和疲劳的数据发表在文献中。在冲击应用中使用3D打印的下一步是评估高分辨率SLA工艺制造均匀抗冲击组件的能力。由于冲击试验是破坏性的,因此还需要建立一种替代措施来检查零件抵抗冲击载荷的可行性。13个缺口Izod标本在Form2 SLA打印机上使用制造商的透明V4光固化树脂打印。一旦所有的样品被打印出来,在异丙醇中洗涤,并在紫外光下固化,使用一个缺口Izod配置的摆锤冲击试验机对其抗冲击性进行量化。然后,采用HBW 10/250标尺对试样的硬度进行量化。透明的SLA聚合物的抗冲击性为0.59±0.14 ft-lb/in。标准上限为0.53 ft-lb/in,工艺能力指数为0.133。抗冲击性和布氏硬度与Spearman系数r = - 0.108, p = 0.73无关。由于工艺能力指数小于1,因此使用SLA聚合物进行3D打印并不是一种可行的制造工艺,无法制造出具有一致抗冲击性的部件。目前的技术会导致太多的不合格品。布氏硬度与冲击强度无显著相关性。因此,在使用前没有非破坏性的方法对这些部件进行抽查。
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引用次数: 0
The Mechanism of Movement and Calculation of Blood Balance in the Flow Channel From the Left Atrium to the End of the Aorta 左心房至主动脉末端血流通道的运动机制及血平衡计算
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-23475
E. Talygin, G. Kiknadze, A. Gorodkov
Today, there are a lot of works studying the mechanisms of formation and evolution of self-organizing tornado-like jets of viscous fluid. In these works, the exact solution of the Navier-Stokes equation for such a class of flows are obtained, the geometry of the generating surface for that flows is established and the necessary and sufficient conditions for the formation and evolution of such swirling jets are formulated. However, important aspects of the mechanics of such flows remain unclear — the structure of the boundary layer, the shape of streamlines in general form, the structure of such flows under a pulsating flow regime, and others. After obtaining the exact solution, attempts were made to obtain relations for streamlines in the corresponding projections. However, due to computational complexity, streamlines were constructed only for regions far from the axis of the swirling flow evolution. In this work, an alternative method of calculating streamlines was used, which made it possible to obtain general relations for these lines at each point in space. Expressions for streamlines contain easily computed functions, which simplifies their practical use Based on the expressions for streamlines, expressions were formulated declaring the conservation of the mass of the swirling blood flow from the left atrium to the aorta and the balance of the medium was calculated. The results of this work are of great theoretical and practical importance. On the one hand, the established expressions for streamlines allow a better study of the mechanisms of formation and evolution of swirling flows in the axial region. On the other hand, obtaining quantitative ratios for the balance of blood in the heart and aorta allows a more accurate study of the mechanics of blood circulation.
目前,对粘性流体自组织的类龙卷风射流的形成和演化机制进行了大量的研究。在这些工作中,获得了这类流动的Navier-Stokes方程的精确解,建立了这类流动的生成面几何形状,并给出了这类旋转射流形成和发展的充分必要条件。然而,这种流动机制的重要方面仍然不清楚——边界层的结构,一般形式的流线的形状,脉动流态下这种流动的结构,等等。在得到精确解后,尝试得到相应投影中流线的关系。然而,由于计算的复杂性,流线只构建在远离漩涡流演化轴的区域。在这项工作中,使用了另一种计算流线的方法,这使得在空间的每个点上获得这些线的一般关系成为可能。流线表达式包含易于计算的函数,简化了其实际应用。在流线表达式的基础上,建立了从左心房流向主动脉的旋涡式血流的质量守恒表达式,并计算了介质的平衡。本文的研究结果具有重要的理论和实践意义。一方面,建立的流线表达式可以更好地研究轴向区旋流的形成和演化机制。另一方面,获得心脏和主动脉中血液平衡的定量比率,可以更准确地研究血液循环的机制。
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引用次数: 0
How Does Physical Activity Affect Residual Limb Volume Change, Comfort and Gait Symmetry on Traumatic Transfemoral Amputees? 体育活动如何影响创伤性经股截肢者残肢体积变化、舒适度和步态对称性?
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-23418
Sara Salazar-Salgado, F. Valencia, A. Uribe, Elizabeth Rendón-Vélez
There is a considerable amount of young adults who become amputees due to war and violence. For this population, a successful adaptation to their prosthesis depends on the socket fit, which in turn is caused by the volume change of the residual limb during the day. The literature reports several investigations on this topic, most of which use subjects walking on a treadmill to simulate their daily activity. However, this studies are focused on transtibial amputees and do not mention the relationship between this physical activity and other variables such as comfort, volume changes and gait. Therefore, the objective of this paper is to determine the effect of physical activity on the volume of the residual limb, the comfort and the symmetry of gait in traumatic transfemoral amputees. Plaster positive molds of the residual limb, the comfort perception and the gait data of five individuals were obtained at the first time of the day and after three sessions of treadmill walking of 15, 30 and 45 minutes. The positive molds of each individual were scanned and then, the volume was calculated. The gait data was acquired using a marker-based motion capture system and processed to obtain spatio-temporal, kinematic and kinetic parameters, including the Gait Deviation Index (GDI). Based on the literature, specific points of the gait data were selected and the symmetry index was obtain for each of them. A short comfort test was used after each session of treadmill walking. Data was analyzed throughout the tests within each subject. Statistical analysis was performed for the volume and the gait variables to check for statistical significance. After physical activity, a tendency towards residual limb volume decrease was found on almost all subjects, although it was not significant. The percentage of volume change obtained on almost all subjects are within the range considered “good socket fit” according to previous authors. Our results suggest that transfemoral amputees may have smaller volume changes than transtibial after treadmill walking. Significant difference was found on the symmetry index of “Swing phase” between the baseline and the 45-minute test. The values of gait symmetry on the gait parameters were consistent with previous findings regarding transfemoral amputees. The difference that arise may be due to the sample difference (cause of amputation, difference in prosthetic elements and use of walking aids). The lowest symmetry was noticed on the ankle kinematics. The comfort did not significantly change with the selected amount of physical activity. In subsequent research, it is recommended to increase the intensity or time of physical activity and/or increase the number of participants. This results can help the understanding of how the socket/residual limb interface behaves which can improve the design and prescription of prosthetic components.
有相当多的年轻人因战争和暴力而截肢。对于这一人群来说,成功地适应他们的假肢取决于插槽的适合度,而这反过来又由残肢在白天的体积变化引起。文献报道了关于这一主题的几项调查,其中大多数使用受试者在跑步机上行走来模拟他们的日常活动。然而,这项研究主要集中在跨胫截肢者身上,并没有提到这种身体活动与其他变量(如舒适度、体积变化和步态)之间的关系。因此,本文的目的是确定体力活动对创伤性经股截肢者残肢体积、舒适性和步态对称性的影响。在每天第一次和在跑步机上行走15、30和45分钟后,分别获得5个人的残肢石膏阳性模型、舒适度感知和步态数据。对每个个体的阳性模具进行扫描,然后计算体积。步态数据采用基于标记的动作捕捉系统获取,并进行处理,获得时空、运动学和动力学参数,包括步态偏差指数(GDI)。在文献的基础上,选取步态数据的特定点,得到每个点的对称性指数。在每次跑步机行走后进行一个简短的舒适测试。在每个受试者的整个测试过程中分析数据。对体积和步态变量进行统计分析,检验有无统计学意义。在体力活动后,几乎所有受试者都有残肢体积减小的趋势,尽管这种趋势并不显著。根据以前的作者,几乎所有受试者的体积变化百分比都在“良好的插槽配合”范围内。我们的研究结果表明,经股骨截肢者在跑步机行走后的体积变化可能比经胫骨截肢者小。基线与45分钟测试在“摇摆期”对称性指标上存在显著差异。步态对称性对步态参数的影响值与先前关于经股截肢者的研究结果一致。产生的差异可能是由于样本差异(截肢的原因,假体元件的差异和助行器的使用)。踝关节运动学的对称性最低。舒适度并没有随着体力活动量的选择而显著改变。在随后的研究中,建议增加体力活动的强度或时间和/或增加参与者的数量。这一结果可以帮助理解窝/残肢界面的行为,从而改进假肢部件的设计和处方。
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引用次数: 0
Testing the Validity of the NIJ Clay Standard for Approving Body Armor With a Preliminary Insight Into Injury Correlation 基于伤害相关性的NIJ Clay防弹衣批准标准有效性测试
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-23886
Madelyn A. K. Eaton, K. Henderson, J. McMahon, R. Salzar
Body armor is tested for efficacy using the NIJ’s clay standard. This standard is based on a 44 mm upper limit of back face deformation into the clay to prevent severe cases of behind armor blunt trauma (BABT). The NIJ clay standard has never been directly correlated with human injury, and it is previously unknown how 44 mm into clay translates to the response of a human torso. This study developed a method for reproducing BABT in a laboratory setting, and performed matched pair testing on the ballistics clay and a cadaveric specimen. Tests at a low, non-injurious speed and a high, injurious speed were performed at the NIJ specified clay temperature, along with two tests at a lower temperature representing exposure to a room temperature setting. It was found that for both speeds the displacement into the human thorax was greater than the displacement into the clay. The greatest displacement into the clay was only 5mm above the standard’s limit, and the same speed into the human model caused failure of the ribcage. Lowering the clay temperature by two degrees Celsius resulted in a passing clay displacement for the extremely injurious high speed test. This experimentation is sufficient in showing that the NIJ standard may not be valid for preventing serious BABT injuries in the wearers of body armor. Further testing is required to correlate clay displacements with human injury risk.
防弹衣的功效测试使用NIJ的粘土标准。这个标准是基于一个44毫米的上限,背部变形到粘土,以防止严重的情况下,背后的装甲钝性创伤(BABT)。NIJ粘土标准从未直接与人类的伤害,这是前所未知的44毫米到粘土转化的反应一个人的躯干。本研究开发了一种在实验室环境下复制BABT的方法,并对弹道学粘土和尸体标本进行了配对测试。测试低,non-injurious速度和高,有害的速度在指定的NIJ粘土的温度下进行,连同两个测试在较低温度下代表暴露在室温环境中。结果发现,在两种速度下,进入人体胸腔的位移都大于进入粘土的位移。最大位移到粘土只有5毫米高于标准的限制,和相同的速度进入人类模型胸腔的失败引起的。将粘土温度降低2摄氏度,使粘土位移通过了极具破坏性的高速试验。这一实验足以表明,NIJ标准可能无法有效防止防弹衣穿戴者受到严重的BABT伤害。需要进一步测试粘土位移与人体伤害风险之间的关系。
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引用次数: 0
Optimum Tick Collection Material and Design for Autonomous Tick Collection Robot 自动蜱虫收集机器人的最佳收集材料与设计
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-24142
Caroline “Niki” Harrison Moretto, Janet Dong, Yesiliang Qiu
This paper discusses the design and testing material utilized to collect ticks from rugged terrain in remote areas via a mobile robot using a mast system, focusing on locating the ideal design and material to ensure maximum tick collection without impacting mobility. Drags are used to collect ticks from short grass, and flags, in the air along the side of the robot, are used to collect ticks from tall grass and shrubs. The design was tested in the field and a laboratory. Cotton and sponge cloth materials were evaluated, along with the shape of the material. The optimum design uses strips of rough sponge cloth to collect ticks. The roughness and fibrous nature of the material increase the number of ticks collected and performed the best of all materials tested. Seams in the sponge cloth allow them to tear away from the robot, if they become tangled in brush, to prevent the robot from being incapacitated. The thickness and weight of the sponge cloth also discourage the material from knotting and entangling with the robot or the environment. The flag attachment points are adjustable horizontally to allow the rearrangement of strips for optimum tick collection. Each strip is designed for independent removal to contain ticks easily and replace strips quickly. Attaching sponge cloth flagging and dragging strips to a mobile robot for tick collection protects humans from a potential illness from bugs and insects carrying disease pathogens, injury from traveling across rough ground, and harm due to exposure to the elements; productivity is also increased. The collection strips should capture ticks despite adverse conditions, be easily interchangeable, and not hinder the tick collection and removal process.
本文讨论了通过使用桅杆系统的移动机器人从偏远地区崎岖地形收集蜱虫的设计和测试材料,重点是确定理想的设计和材料,以确保在不影响机动性的情况下最大限度地收集蜱虫。拖状物用于收集短草上的蜱虫,而悬挂在机器人旁边的旗子用于收集高草和灌木上的蜱虫。该设计已在现场和实验室进行了测试。评估了棉和海绵布材料,以及材料的形状。最优的设计是使用粗糙的海绵布条来收集蜱虫。材料的粗糙度和纤维性增加了收集到的蜱虫数量,在所有测试材料中表现最好。海绵布的接缝可以让它们在被刷子缠住时脱离机器人,以防止机器人失去行动能力。海绵布的厚度和重量也可以防止材料与机器人或环境打结和纠缠。旗子附着点是水平可调的,以便重新安排条带,以获得最佳的蜱虫收集。每个条带都是为独立去除而设计的,可以轻松地包含蜱虫并快速更换条带。在收集蜱虫的移动机器人上安装海绵布标记和拖拽条,可以保护人类免受携带疾病病原体的臭虫和昆虫的潜在疾病,穿越粗糙地面造成的伤害,以及暴露在自然环境中的伤害;生产力也提高了。收集条应在不利条件下捕获蜱虫,易于互换,并且不妨碍蜱虫收集和清除过程。
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引用次数: 0
Effect of Additional Weight on Lyapunov Exponents for Human Squat Exercise 额外重量对人体深蹲运动李雅普诺夫指数的影响
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-23943
J. Galarza, D. Caruntu
This work deals with the stability of the dynamics of human squat exercise. This is a common exercise. The focus of this investigation is to analyze the knee angle time series and calculate the divergence for different weight added in the exercise. Experiments are conducted and motion capture used for each of the cases. Then the Lyapunov exponents of the time series of the knee joint angle are determined. Matlab software package is used for all calculations. Results are compared with data available in the literature. This work provides insight on the level of stability for added weight on the human squat exercise. This gives an insight on the level of safety of this exercise as weight is added to the human subject.
这项工作涉及人类深蹲运动的动力学稳定性。这是一个常见的练习。本研究的重点是分析膝关节角度的时间序列,并计算不同重量在运动中的发散度。对每种情况进行了实验和动作捕捉。然后确定膝关节角度时间序列的Lyapunov指数。所有计算均采用Matlab软件包。结果与文献资料进行了比较。这项工作为人类深蹲运动中增加重量的稳定性水平提供了见解。这让我们了解到,随着人体重量的增加,这项运动的安全程度。
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引用次数: 0
Influence of Composite Polymer Coatings on the Insertion Force of Needle-Like Structure in Soft Materials 复合聚合物涂层对软质材料针状结构插入力的影响
Pub Date : 2020-11-16 DOI: 10.1115/IMECE2020-24341
Kavi Patel, Long Zhu, S. T. R. Gidde, Fei Ren, P. Hutapea
This study is aimed to evaluate the effects of coated surgical needles with composite polymers such as polydopamine (PDA), polytetrafluoroethylene (PTFE), and carbon. The coated needle’s lubrication properties were measured using 3 DOF force sensors and 3D robot system by the repetitive insertion in soft tissue materials. Needle durability is a measure of needle sharpness after repeated passage through high stiffness tissue materials. The composite coatings were shown to reduce the insertion force by ∼49% and retraction forces by ∼46% when tested using a bovine kidney. The surface roughness and the lateral friction force of the needle are measured using the Atomic Force Microscope (AFM). The adhesion energy of the different coating on the needle will be measured using a nano-scratch method.
本研究旨在评估复合聚合物如聚多巴胺(PDA)、聚四氟乙烯(PTFE)和碳涂层手术针的效果。利用三自由度力传感器和三维机器人系统,通过在软组织材料中重复插入的方式,对涂层针的润滑性能进行了测试。针的耐久性是指在高刚度组织材料中反复穿过后,针的锋利程度。在使用牛肾脏进行测试时,复合涂层可将插入力降低~ 49%,收回力降低~ 46%。利用原子力显微镜(AFM)测量了针的表面粗糙度和侧向摩擦力。用纳米划痕法测量不同涂层在针上的粘附能。
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引用次数: 0
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