首页 > 最新文献

Volume 5: Biomedical and Biotechnology最新文献

英文 中文
Design and Development of a Reconfigurable and Adjustable Compliance System for the Measurement of Orthotic Properties 一种可重构可调矫形性能测量顺应系统的设计与开发
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-70326
Yaru Mo, Zeeshan Qaiser, Shane Johnson
Custom foot orthoses (CFOs) are effective in the prevention and treatment of lower extremity injuries (LEIs). However, the current design methodologies of CFOs are not efficient due to the limited consideration of soft tissue impedance, orthotic properties and subjective feedback during the measurement. A new design methodology of CFOs is required to determine the desired orthotic properties including geometry and impedance, which satisfy pressure/load distribution, subjective comfort and reduce iterations. A measurement device which provides an Interface with Tunable Ergonomic properties using a Reconfigurable Framework with Adjustable Compliant Elements (INTERFACE) is developed. The INTERFACE system provides locally adjustable geometry and stiffness for the support of Medial Longitudinal Arch (MLA) by applying a mechanism with six degrees of freedom and three Tunable Stiffness Mechanisms (TSMs). Therefore, the Rapid Evaluate and Adjust Device (READ) Methodology can be implemented by adjusting the interface properties based on the pressure/load and subjective evaluation. The prototype of the INTERFACE system was fabricated to conduct the validation test on 10 subjects, in which the interface pressure/load distribution and subjective feedback in different combinations of geometry and stiffness were recorded. The plantar pressure/load increased with stiffness and geometrical height, and the significance has been demonstrated by a correlation analysis. Subjective comfort can be achieved with different combinations of geometry and stiffness. The proposed INTERFACE system can be employed to conduct the plantar measurement to obtain the desired orthotic properties which satisfy objective and subjective requirements.
定制足部矫形器(CFOs)在预防和治疗下肢损伤(lei)方面是有效的。然而,由于在测量过程中对软组织阻抗、矫形特性和主观反馈的考虑有限,目前的cfo设计方法效率不高。需要一种新的cfo设计方法来确定所需的正形特性,包括几何和阻抗,以满足压力/负载分布,主观舒适性和减少迭代。研制了一种基于可重构框架和可调柔性元件(Interface)的人机工程学可调接口测量装置。INTERFACE系统通过采用具有6个自由度和3个可调刚度机构(TSMs)的机构,为内侧纵弓(MLA)的支撑提供局部可调的几何形状和刚度。因此,快速评估和调整装置(READ)方法可以通过根据压力/负载和主观评价来调整界面特性来实现。制作了INTERFACE系统的原型,对10名被试进行了验证试验,记录了不同几何形状和刚度组合下界面压力/载荷分布和主观反馈。足底压力/载荷随刚度和几何高度的增加而增加,相关分析证明了这一意义。主观舒适度可以通过不同的几何形状和刚度组合来实现。所提出的INTERFACE系统可用于足底测量,以获得满足客观和主观要求的所需矫形性能。
{"title":"Design and Development of a Reconfigurable and Adjustable Compliance System for the Measurement of Orthotic Properties","authors":"Yaru Mo, Zeeshan Qaiser, Shane Johnson","doi":"10.1115/imece2021-70326","DOIUrl":"https://doi.org/10.1115/imece2021-70326","url":null,"abstract":"\u0000 Custom foot orthoses (CFOs) are effective in the prevention and treatment of lower extremity injuries (LEIs). However, the current design methodologies of CFOs are not efficient due to the limited consideration of soft tissue impedance, orthotic properties and subjective feedback during the measurement. A new design methodology of CFOs is required to determine the desired orthotic properties including geometry and impedance, which satisfy pressure/load distribution, subjective comfort and reduce iterations. A measurement device which provides an Interface with Tunable Ergonomic properties using a Reconfigurable Framework with Adjustable Compliant Elements (INTERFACE) is developed. The INTERFACE system provides locally adjustable geometry and stiffness for the support of Medial Longitudinal Arch (MLA) by applying a mechanism with six degrees of freedom and three Tunable Stiffness Mechanisms (TSMs). Therefore, the Rapid Evaluate and Adjust Device (READ) Methodology can be implemented by adjusting the interface properties based on the pressure/load and subjective evaluation. The prototype of the INTERFACE system was fabricated to conduct the validation test on 10 subjects, in which the interface pressure/load distribution and subjective feedback in different combinations of geometry and stiffness were recorded. The plantar pressure/load increased with stiffness and geometrical height, and the significance has been demonstrated by a correlation analysis. Subjective comfort can be achieved with different combinations of geometry and stiffness. The proposed INTERFACE system can be employed to conduct the plantar measurement to obtain the desired orthotic properties which satisfy objective and subjective requirements.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115404881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design, Prototyping, and Testing of a Robotic Prosthetic Leg Preliminary Results 机器人假肢的设计、原型制作和测试初步结果
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-68786
Michael Davidson, N. Daher, Thomas Fryer, Johannes Schaepper, D. Tran
We report on our design and initial evaluation of a prototype robotic prosthetic leg (RPL) with a powered non-backdrivable knee and a hydro-pneumatic passive-resistive ankle. Our design was intended to increase health providers’ opportunities when offering their patients greater options, expanding the accessibility of advanced technology to those with lower functional levels of ambulation while decreasing the overall costs of care. The purpose of this biomedical device was to improve stance stability, increase balance confidence, and through powered-knee extension, reduce the contralateral limb’s kinetic stresses in gait, sitting, and standing. This device was designed to provide K2 and above ambulators a more adaptive, safe, and enhanced lower limb prosthesis. The prototype was assessed on a healthy subject while performing multiple 10-meter walk tests (10MWT) and six-minute walk tests (6MWT) on level-ground, inclines, and declines. We report walking velocity, the frequency of steps, cadence, falls, stumbles, toe-drags, battery consumption, and estimated torque of the knee actuator. We found the device safe on an able-bodied subject and feasible for future use on persons with limb loss.
我们报告了一个原型机器人假肢(RPL)的设计和初步评估,该假肢具有动力非反向驱动膝盖和液压气动被动电阻脚踝。我们的设计旨在增加医疗服务提供者的机会,为他们的患者提供更多的选择,扩大先进技术的可及性,同时降低护理的总体成本。该生物医学装置的目的是改善姿态稳定性,增加平衡信心,并通过膝关节的动力伸展,减少对侧肢体在步态、坐姿和站立时的运动应力。该装置旨在为K2及以上的步行器提供更适应性、更安全、更强的下肢假体。该原型在健康受试者身上进行了多次10米步行测试(10MWT)和6分钟步行测试(6MWT),并在平地、斜坡和斜坡上进行了评估。我们报告了行走速度、步频、节奏、跌倒、绊倒、脚拖、电池消耗和膝关节致动器的估计扭矩。我们发现这个装置在身体健全的人身上是安全的,将来在肢体丧失的人身上也是可行的。
{"title":"Design, Prototyping, and Testing of a Robotic Prosthetic Leg Preliminary Results","authors":"Michael Davidson, N. Daher, Thomas Fryer, Johannes Schaepper, D. Tran","doi":"10.1115/imece2021-68786","DOIUrl":"https://doi.org/10.1115/imece2021-68786","url":null,"abstract":"\u0000 We report on our design and initial evaluation of a prototype robotic prosthetic leg (RPL) with a powered non-backdrivable knee and a hydro-pneumatic passive-resistive ankle. Our design was intended to increase health providers’ opportunities when offering their patients greater options, expanding the accessibility of advanced technology to those with lower functional levels of ambulation while decreasing the overall costs of care. The purpose of this biomedical device was to improve stance stability, increase balance confidence, and through powered-knee extension, reduce the contralateral limb’s kinetic stresses in gait, sitting, and standing. This device was designed to provide K2 and above ambulators a more adaptive, safe, and enhanced lower limb prosthesis. The prototype was assessed on a healthy subject while performing multiple 10-meter walk tests (10MWT) and six-minute walk tests (6MWT) on level-ground, inclines, and declines. We report walking velocity, the frequency of steps, cadence, falls, stumbles, toe-drags, battery consumption, and estimated torque of the knee actuator. We found the device safe on an able-bodied subject and feasible for future use on persons with limb loss.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116355785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Preliminary Study: Development of Sport Climbing Hold Measurement System for Performance Analysis 运动攀爬持力测量系统的初步研究
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-67624
Nina Pernuš, D. Munro
Sport climbing performance analysis requires knowledge of the specific motions and the interactions of the athlete with the climbing holds. The objective of this research is to develop a low-cost measurement system for detecting performance parameters with an instrument mounting screw used with a climbing hold. In the preliminary study, strain gauges were bonded to the shank of a screw and analyzed according to bending theory. For the experimental results, a climbing hold was mounted to a provisional wall with an instrumented mounting screw. The system was able to detect loads at increments of 2 kg applied to the climbing hold with accuracy and repeatability. Testing of loading when applied laterally from the center of the climbing hold showed that the alignment of the strain gauge and location of applied loads are important. The measurement system was capable of identifying the total contact time and time for each application of loads more than 1 kg. Results showed an instrumented mounting screw can be used for monitoring the climber’s fluency during climbing and provide information about load distribution between climbing holds during their ascent.
运动攀爬性能分析需要了解具体的动作和运动员与攀爬点的相互作用。本研究的目的是开发一种低成本的测量系统,用于检测性能参数,该系统使用带有爬升支架的仪器安装螺钉。在初步研究中,将应变片粘接在螺杆上,并根据弯曲理论进行了分析。为了得到实验结果,我们用仪器安装螺钉将一个攀爬支架安装在临时壁上。该系统能够以精确和可重复性的方式检测施加在攀爬支架上的2千克增量载荷。从攀爬舱中心横向施加载荷的测试表明,应变片的对准和施加载荷的位置是重要的。该测量系统能够识别总接触时间和每次施加超过1kg负载的时间。结果表明,安装螺钉可以监测攀爬者在攀爬过程中的流畅性,并提供攀爬过程中各攀爬点之间载荷分布的信息。
{"title":"Preliminary Study: Development of Sport Climbing Hold Measurement System for Performance Analysis","authors":"Nina Pernuš, D. Munro","doi":"10.1115/imece2021-67624","DOIUrl":"https://doi.org/10.1115/imece2021-67624","url":null,"abstract":"\u0000 Sport climbing performance analysis requires knowledge of the specific motions and the interactions of the athlete with the climbing holds. The objective of this research is to develop a low-cost measurement system for detecting performance parameters with an instrument mounting screw used with a climbing hold. In the preliminary study, strain gauges were bonded to the shank of a screw and analyzed according to bending theory. For the experimental results, a climbing hold was mounted to a provisional wall with an instrumented mounting screw. The system was able to detect loads at increments of 2 kg applied to the climbing hold with accuracy and repeatability. Testing of loading when applied laterally from the center of the climbing hold showed that the alignment of the strain gauge and location of applied loads are important. The measurement system was capable of identifying the total contact time and time for each application of loads more than 1 kg. Results showed an instrumented mounting screw can be used for monitoring the climber’s fluency during climbing and provide information about load distribution between climbing holds during their ascent.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131684114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging Vibrations and Guided Waves in a Human Skull 利用人类头骨中的振动和导波
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-71315
E. Kohtanen, M. Mazzotti, M. Ruzzene, A. Erturk
This work is centered on high-fidelity modeling, analysis, and rigorous experiments of vibrations and guided (Lamb) waves in a human skull in two connected tracks: (1) layered modeling of the cranial bone structure (with cortical tables and diploë) and its vibration-based elastic parameter identification (and validation); (2) transcranial leaky Lamb wave characterization experiments and radiation analyses using the identified elastic parameters in a layered semi analytical finite element framework, followed by time transient simulations that consider the inner porosity as is. In the first track, non-contact vibration experiments are conducted to extract the first handful of modal frequencies in the auditory frequency regime, along with the associated damping ratios and mode shapes, of dry cranial bone segments extracted from the parietal and frontal regions of a human skull. Numerical models of the bone segments are built with a novel image reconstruction scheme that employs microcomputed tomographic scans to build a layered bone geometry with separate homogenized domains for the cortical tables and the diploë. These numerical models and the experimental modal frequencies are then used in an iterative parameter identification scheme that yields the cortical and diploic isotropic elastic moduli of each domain, whereas the corresponding densities are estimated using the total experimental mass and layer mass ratios obtained from the scans. With the identified elastic parameters, the average error between experimental and numerical modal frequencies is less than 1.5% and the modal assurance criterion values for most modes are above 0.90. Furthermore, the extracted parameters are in the range of the results reported in the literature. In the second track, the focus is placed on the subject of leaky Lamb waves, which has received growing attention as a promising alternative to conventional ultrasound techniques for transcranial transmission, especially to access the brain periphery. Experiments are conducted on the same cranial bone segment set for leaky Lamb wave excitation and radiation characterization. The degassed skull bone segments are used in submersed experiments with an ultrasonic transducer and needle hydrophone setup for radiation pressure field scanning. Elastic parameters obtained from the first track are used in guided wave dispersion simulations, and the radiation angles are accurately predicted using the aforementioned layered model in the presence of fluid loading. The dominant radiation angles are shown to correspond to guided wave modes with low attenuation and a significant out-of-plane polarization. The experimental radiation spectra are finally compared against those obtained from time transient finite element simulations that leverage geometric models reconstructed from microcomputed tomographic scans.
这项工作集中在高保真建模,分析和严格的实验振动和引导(Lamb)波在人类头骨在两个相连的轨道:(1)颅骨结构的分层建模(与皮质表和diploë)及其基于振动的弹性参数识别(和验证);(2)在层状半解析有限元框架下,利用识别出的弹性参数进行经颅泄漏Lamb波表征实验和辐射分析,然后进行考虑内部孔隙度的时间瞬态模拟。在第一轨道中,进行了非接触振动实验,以提取听觉频率范围内的前几个模态频率,以及从人类头骨的顶叶和额叶区域提取的干颅骨片段的相关阻尼比和模态振型。骨段的数值模型是用一种新的图像重建方案建立的,该方案采用微计算机断层扫描来建立分层的骨几何结构,并为皮质表和diploë提供单独的均匀化域。然后将这些数值模型和实验模态频率用于迭代参数识别方案,该方案产生每个域的皮质和双质体各向同性弹性模量,而使用从扫描中获得的总实验质量和层质量比来估计相应的密度。在确定的弹性参数下,试验模态频率与数值模态频率的平均误差小于1.5%,大多数模态的模态保证准则值在0.90以上。此外,提取的参数在文献报道的结果范围内。在第二个轨道上,重点放在泄漏兰姆波的主题上,作为一种有前途的替代传统超声技术的经颅传输,特别是进入大脑外围,已受到越来越多的关注。在同一组颅骨骨段上进行漏兰姆波激发和辐射表征实验。利用超声换能器和针状水听器装置对脱气后的颅骨片段进行了水下辐射压力场扫描实验。利用第一航迹得到的弹性参数进行导波频散模拟,利用上述分层模型准确预测了流体加载下的辐射角。主辐射角对应的导波模式具有低衰减和显着的面外偏振。最后,将实验辐射光谱与利用从微计算机层析扫描重建的几何模型进行的时间瞬态有限元模拟所得的辐射光谱进行比较。
{"title":"Leveraging Vibrations and Guided Waves in a Human Skull","authors":"E. Kohtanen, M. Mazzotti, M. Ruzzene, A. Erturk","doi":"10.1115/imece2021-71315","DOIUrl":"https://doi.org/10.1115/imece2021-71315","url":null,"abstract":"\u0000 This work is centered on high-fidelity modeling, analysis, and rigorous experiments of vibrations and guided (Lamb) waves in a human skull in two connected tracks: (1) layered modeling of the cranial bone structure (with cortical tables and diploë) and its vibration-based elastic parameter identification (and validation); (2) transcranial leaky Lamb wave characterization experiments and radiation analyses using the identified elastic parameters in a layered semi analytical finite element framework, followed by time transient simulations that consider the inner porosity as is. In the first track, non-contact vibration experiments are conducted to extract the first handful of modal frequencies in the auditory frequency regime, along with the associated damping ratios and mode shapes, of dry cranial bone segments extracted from the parietal and frontal regions of a human skull. Numerical models of the bone segments are built with a novel image reconstruction scheme that employs microcomputed tomographic scans to build a layered bone geometry with separate homogenized domains for the cortical tables and the diploë. These numerical models and the experimental modal frequencies are then used in an iterative parameter identification scheme that yields the cortical and diploic isotropic elastic moduli of each domain, whereas the corresponding densities are estimated using the total experimental mass and layer mass ratios obtained from the scans. With the identified elastic parameters, the average error between experimental and numerical modal frequencies is less than 1.5% and the modal assurance criterion values for most modes are above 0.90. Furthermore, the extracted parameters are in the range of the results reported in the literature. In the second track, the focus is placed on the subject of leaky Lamb waves, which has received growing attention as a promising alternative to conventional ultrasound techniques for transcranial transmission, especially to access the brain periphery. Experiments are conducted on the same cranial bone segment set for leaky Lamb wave excitation and radiation characterization. The degassed skull bone segments are used in submersed experiments with an ultrasonic transducer and needle hydrophone setup for radiation pressure field scanning. Elastic parameters obtained from the first track are used in guided wave dispersion simulations, and the radiation angles are accurately predicted using the aforementioned layered model in the presence of fluid loading. The dominant radiation angles are shown to correspond to guided wave modes with low attenuation and a significant out-of-plane polarization. The experimental radiation spectra are finally compared against those obtained from time transient finite element simulations that leverage geometric models reconstructed from microcomputed tomographic scans.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132569153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Parametric Study: Influence of Geometry and Material Properties on the Response of the Femoral Head Through Biofluid 参数化研究:几何和材料特性对股骨头通过生物流体反应的影响
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-70061
M. Paliwal
Friction-induced stick-slip phenomenon has been reported in 1–20% of patients with ceramic-on-ceramic total hip replacement. The friction behavior of the bearing surfaces is ruled by the lubrication conditions, which may be from hydrodynamic lubrication to mixed or boundary lubrication. In the latter two situations, surface-to-surface mechanical contact may give rise to the friction-induced stick-slip phenomenon. Essentially, stick-slip occurs when the film lubrication is broken. Stick-slip is an undesired phenomenon and is understood to give rise to the squeaking phenomenon in the hip bearing surfaces. In this study, the influence of the relative densities of biofluid, size, mass, and femoral head material is investigated to study the system’s response and the approach of the femoral head towards the acetabulum shell (initial contact to pre-swing phase). Two configurations were developed, which included ball-on-plane and ballon socket configurations. Utilizing parametric studies, the role of these variables was studied. Higher velocity-derived energy may contribute to the vibration of the system via stick-slip. High approach velocity combined with high-density material may influence and lead to surface-surface articulation.
据报道,1-20%的陶瓷对陶瓷全髋关节置换术患者存在摩擦引起的粘滑现象。轴承表面的摩擦行为受润滑条件的支配,润滑条件可能是从流体动力润滑到混合润滑或边界润滑。在后两种情况下,表面与表面的机械接触可能会引起摩擦引起的粘滑现象。本质上,当膜润滑被破坏时,就会发生粘滑。粘滑是一种不希望出现的现象,据了解,它会引起髋关节轴承表面的吱吱声现象。在这项研究中,研究了生物流体的相对密度、大小、质量和股骨头材料的影响,以研究系统的反应和股骨头向髋臼壳的接近(初始接触到预摆阶段)。开发了两种配置,包括平面球和球窝配置。利用参数研究,研究了这些变量的作用。较高的速度衍生能量可能导致系统通过粘滑产生振动。高接近速度与高密度材料结合可能影响并导致表面关节。
{"title":"A Parametric Study: Influence of Geometry and Material Properties on the Response of the Femoral Head Through Biofluid","authors":"M. Paliwal","doi":"10.1115/imece2021-70061","DOIUrl":"https://doi.org/10.1115/imece2021-70061","url":null,"abstract":"\u0000 Friction-induced stick-slip phenomenon has been reported in 1–20% of patients with ceramic-on-ceramic total hip replacement. The friction behavior of the bearing surfaces is ruled by the lubrication conditions, which may be from hydrodynamic lubrication to mixed or boundary lubrication. In the latter two situations, surface-to-surface mechanical contact may give rise to the friction-induced stick-slip phenomenon. Essentially, stick-slip occurs when the film lubrication is broken. Stick-slip is an undesired phenomenon and is understood to give rise to the squeaking phenomenon in the hip bearing surfaces. In this study, the influence of the relative densities of biofluid, size, mass, and femoral head material is investigated to study the system’s response and the approach of the femoral head towards the acetabulum shell (initial contact to pre-swing phase). Two configurations were developed, which included ball-on-plane and ballon socket configurations. Utilizing parametric studies, the role of these variables was studied. Higher velocity-derived energy may contribute to the vibration of the system via stick-slip. High approach velocity combined with high-density material may influence and lead to surface-surface articulation.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130319431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the Difference in Cortical Bone Adaptation at Endocortical and Periosteal Surfaces by Fluid Flow Analysis 通过流体流动分析研究皮质内表面和骨膜表面皮质骨适应的差异
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-71220
Sanjay Singh, Satwinder Singh, Jitendra Prasad
Load-induced fluid flow in lacunar-canalicular porosity in bone has been suggested to play an essential role in bone adaptation. The applied load causes the fluid inside the lacunar-canalicular system to flow. The osteocytes are believed to sense the shear stress exerted due to the fluid flow and drive new bone formation. The energy dissipated in moving fluid may be considered as a stimulus for bone adaptation. The endocortical bone surfaces are also believed to adapt differently compared to the periosteal surfaces. We investigate such differences and present a finite element poroelasticity-based mathematical model on estimating bone formation rate at mid-diaphysis of a C57BL6 mouse tibia subjected to cantilever loading. A weighted average of dissipation energy in the zone of influence has been considered in accordance with the literature. The model predicts bone formation rate (BFR) at the periosteal surface as well as on the endocortical surface. As desired, the model can differentiate between a continuous cyclic loading and a rest-inserted cyclic loading. The model establishes that the difference in bone formation at the two surfaces, viz. endocortical and periosteal, may be due to the difference in dissipation energy density only, caused by different boundary conditions at the two surfaces.
载荷诱导的流体在骨腔管孔隙中的流动被认为在骨适应中起重要作用。施加的载荷使腔管系统内的流体流动。骨细胞被认为能够感知由于流体流动而施加的剪切应力并驱动新骨的形成。在运动流体中耗散的能量可被认为是骨适应的一种刺激。与骨膜表面相比,皮质内骨表面也被认为具有不同的适应性。我们研究了这些差异,并提出了一个基于有限元孔隙弹性的数学模型,用于估计C57BL6小鼠胫骨在悬臂载荷下的中骨干骨形成率。根据文献考虑了影响区耗散能的加权平均值。该模型预测骨膜表面和皮质内表面的骨形成率(BFR)。根据需要,该模型可以区分连续循环加载和插入休息循环加载。该模型表明,在皮质内和骨膜两个表面上骨形成的差异可能仅仅是由于两个表面上不同的边界条件引起的耗散能密度的差异。
{"title":"Investigating the Difference in Cortical Bone Adaptation at Endocortical and Periosteal Surfaces by Fluid Flow Analysis","authors":"Sanjay Singh, Satwinder Singh, Jitendra Prasad","doi":"10.1115/imece2021-71220","DOIUrl":"https://doi.org/10.1115/imece2021-71220","url":null,"abstract":"\u0000 Load-induced fluid flow in lacunar-canalicular porosity in bone has been suggested to play an essential role in bone adaptation. The applied load causes the fluid inside the lacunar-canalicular system to flow. The osteocytes are believed to sense the shear stress exerted due to the fluid flow and drive new bone formation. The energy dissipated in moving fluid may be considered as a stimulus for bone adaptation. The endocortical bone surfaces are also believed to adapt differently compared to the periosteal surfaces. We investigate such differences and present a finite element poroelasticity-based mathematical model on estimating bone formation rate at mid-diaphysis of a C57BL6 mouse tibia subjected to cantilever loading. A weighted average of dissipation energy in the zone of influence has been considered in accordance with the literature. The model predicts bone formation rate (BFR) at the periosteal surface as well as on the endocortical surface. As desired, the model can differentiate between a continuous cyclic loading and a rest-inserted cyclic loading. The model establishes that the difference in bone formation at the two surfaces, viz. endocortical and periosteal, may be due to the difference in dissipation energy density only, caused by different boundary conditions at the two surfaces.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130821552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMECE2021 Front Matter IMECE2021前沿问题
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-fm5
The front matter for this proceedings is available by clicking on the PDF icon.
通过点击PDF图标可获得本次会议的主题。
{"title":"IMECE2021 Front Matter","authors":"","doi":"10.1115/imece2021-fm5","DOIUrl":"https://doi.org/10.1115/imece2021-fm5","url":null,"abstract":"\u0000 The front matter for this proceedings is available by clicking on the PDF icon.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126477848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electro-Mechanical Design Toward an Open-Sourced Robotic Hand Exoskeleton for Management of Neurological and Neurodegenerative Disorders 面向神经和神经退行性疾病管理的开放源代码机器人手外骨骼的机电设计
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-73668
James E. Bednar, M. Schwartz, John Woo, D. Dow, G. Ma, Marisha Rawlins, Filip Cuckov
Impaired hand motor function degrades performance of activities of daily living (ADL). Exoskeleton devices can assist hand function for ADL, but the associated cost and complexity limit access for many individuals who would otherwise benefit and impedes development for improved devices. A simpler, but functional, open-source design for a hand assistive exoskeleton might expand accessibility and accelerate development. In this paper, we present an electromechanical prototype of a hand exoskeleton that was designed, implemented, and tested for digit extension and flexing. The design and prototype assisted actuation of an individual finger digit using a sliding spring mechanism. The mechanism is a type of underactuated mechanism that converts one degree of freedom linear motion into rotational motion. The resulting prototype was subjected to motion and force testing, with results supporting certain functional aspects of the system. Further development and testing need to be done for the proposed exoskeleton design, especially as an open-source design. Being open-source would widen access, accelerate development, and improve the quality of life for many individuals.
手部运动功能受损会降低日常生活活动(ADL)的表现。外骨骼设备可以辅助ADL的手部功能,但相关的成本和复杂性限制了许多个人的使用,否则他们将受益并阻碍改进设备的开发。一种更简单但功能强大的手辅助外骨骼开源设计可能会扩大可访问性并加速开发。在本文中,我们提出了一个手外骨骼的机电原型,设计、实现和测试了手指的伸展和弯曲。该设计和原型使用滑动弹簧机构辅助单个手指的驱动。该机构是一种将一个自由度的直线运动转化为旋转运动的欠驱动机构。由此产生的原型进行了运动和力测试,结果支持系统的某些功能方面。对于提议的外骨骼设计,特别是作为开源设计,需要进行进一步的开发和测试。开源将扩大访问,加速开发,并提高许多人的生活质量。
{"title":"Electro-Mechanical Design Toward an Open-Sourced Robotic Hand Exoskeleton for Management of Neurological and Neurodegenerative Disorders","authors":"James E. Bednar, M. Schwartz, John Woo, D. Dow, G. Ma, Marisha Rawlins, Filip Cuckov","doi":"10.1115/imece2021-73668","DOIUrl":"https://doi.org/10.1115/imece2021-73668","url":null,"abstract":"\u0000 Impaired hand motor function degrades performance of activities of daily living (ADL). Exoskeleton devices can assist hand function for ADL, but the associated cost and complexity limit access for many individuals who would otherwise benefit and impedes development for improved devices. A simpler, but functional, open-source design for a hand assistive exoskeleton might expand accessibility and accelerate development. In this paper, we present an electromechanical prototype of a hand exoskeleton that was designed, implemented, and tested for digit extension and flexing. The design and prototype assisted actuation of an individual finger digit using a sliding spring mechanism. The mechanism is a type of underactuated mechanism that converts one degree of freedom linear motion into rotational motion. The resulting prototype was subjected to motion and force testing, with results supporting certain functional aspects of the system. Further development and testing need to be done for the proposed exoskeleton design, especially as an open-source design. Being open-source would widen access, accelerate development, and improve the quality of life for many individuals.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129417130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Additive Manufacturing Process Parameter Optimization for Titanium-Alloy Orthopedic Implants 钛合金骨科植入物增材制造工艺参数优化
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-70436
B. Gaur, Rupesh Ghyar, B. Ravi
Orthopedic implants are widely used for treating bone tumors and trauma defects in patients. The complex and organic geometry of patient-customized implants (PCIs) required in single order quantity makes them suitable for fabrication using additive manufacturing technologies such as Laser beam powder bed fusion. While there is considerable technical literature on these technologies, the choice of optimal process parameters to obtain the required quality considering the relevant applicable international quality standards for orthopedic implants is still a major challenge for the manufacturers. This experimental work relies on the minimum requirements of various mechanical properties recommended by ASTM F3001-14 and ASTM F136-13 standards for determining the optimal process parameters for PCI manufacture. Ti6Al4V ELI (Titanium–6Aluminum–4Vanadium Extra-Low-Interstitial) alloy test samples were fabricated using a Direct Metal Laser Sintering (DMLS) system. The three most critical printing parameters, namely, laser power, laser velocity and hatch distance, were varied in three levels using the Taguchi approach. Properties such as ultimate tensile strength, percentage elongation and part density were considered for optimizing the process parameter combinations using VIKOR, a multi-criteria decision-making technique. The results show that a combination of moderate laser power, high laser velocity and low hatch distance values produce implants with superior mechanical properties. The proposed methodology and results are expected to help researchers and manufacturers in choosing the initial process parameters for PCI fabrication.
骨科植入物广泛应用于骨肿瘤和创伤性骨缺损的治疗。单次订购所需的患者定制植入物(pci)的复杂和有机几何形状使其适合使用激光粉末床融合等增材制造技术进行制造。虽然关于这些技术有相当多的技术文献,但考虑到相关适用的骨科植入物的国际质量标准,选择最佳工艺参数以获得所需的质量仍然是制造商面临的主要挑战。这项实验工作依赖于ASTM F3001-14和ASTM F136-13标准推荐的各种机械性能的最低要求,以确定PCI制造的最佳工艺参数。采用直接金属激光烧结(DMLS)系统制备了Ti6Al4V ELI(钛- 6铝- 4钒特低间隙)合金试样。采用田口方法对三个最关键的打印参数,即激光功率、激光速度和孵化距离进行了三个水平的变化。使用VIKOR(一种多准则决策技术)优化工艺参数组合时,考虑了极限抗拉强度、伸长率和零件密度等性能。结果表明,适当的激光功率、较高的激光速度和较低的孵化距离可以获得优异的力学性能。所提出的方法和结果有望帮助研究人员和制造商选择PCI制造的初始工艺参数。
{"title":"Additive Manufacturing Process Parameter Optimization for Titanium-Alloy Orthopedic Implants","authors":"B. Gaur, Rupesh Ghyar, B. Ravi","doi":"10.1115/imece2021-70436","DOIUrl":"https://doi.org/10.1115/imece2021-70436","url":null,"abstract":"\u0000 Orthopedic implants are widely used for treating bone tumors and trauma defects in patients. The complex and organic geometry of patient-customized implants (PCIs) required in single order quantity makes them suitable for fabrication using additive manufacturing technologies such as Laser beam powder bed fusion. While there is considerable technical literature on these technologies, the choice of optimal process parameters to obtain the required quality considering the relevant applicable international quality standards for orthopedic implants is still a major challenge for the manufacturers.\u0000 This experimental work relies on the minimum requirements of various mechanical properties recommended by ASTM F3001-14 and ASTM F136-13 standards for determining the optimal process parameters for PCI manufacture. Ti6Al4V ELI (Titanium–6Aluminum–4Vanadium Extra-Low-Interstitial) alloy test samples were fabricated using a Direct Metal Laser Sintering (DMLS) system. The three most critical printing parameters, namely, laser power, laser velocity and hatch distance, were varied in three levels using the Taguchi approach. Properties such as ultimate tensile strength, percentage elongation and part density were considered for optimizing the process parameter combinations using VIKOR, a multi-criteria decision-making technique. The results show that a combination of moderate laser power, high laser velocity and low hatch distance values produce implants with superior mechanical properties. The proposed methodology and results are expected to help researchers and manufacturers in choosing the initial process parameters for PCI fabrication.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115227799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary Design and Experimental Studies of a Compliant Knee Joint for Pediatric Above Knee Amputees 儿童膝以上截肢者柔性膝关节的初步设计与实验研究
Pub Date : 2021-11-01 DOI: 10.1115/imece2021-73655
Sahil Pitre, Bryan Curtin, P. Pena, Ciaphus Rouse, E. Joseph, Joshua Hooper, A. Tekes
This study presents a passive, self-actuated, 3D printed compliant knee joint for children in developing regions to decrease the overall expense of above knee prosthesis as well as increase the ease to print multiple prosthesis during their growing cycle. A single piece designed five-bar mechanism is proposed to provide adequate human-like gait instead of the traditional pegleg gait provided in previous rigid models. This gait is achieved through the use of both compliant links as well a novel 3D printed approach which is more accustomed to children because of the mechanism’s lightweight. In addition to the compliant knee joint, a compliant ankle possessing a flexure hinge placed at the toe is also designed to provide required bending during the gait cycle. The approach of using a fully passive knee joint enables to limit the weight of the prosthesis to create less of a burden to children and by isolating the need to utilize motors. A test bench consisted of a rack-pinion, two parallel rods, supports, and two servo motors are fabricated to experiment the performance of the knee joint. While the test bench is 3D printed using polylactic acid (PLA), the compliant knee joint is 3D printed in thermoplastic polyurethane (TPU) to emulate the gestures of a real human leg. Simulations are performed in Matlab Simscape to validate that the proposed knee joint mimics the human knee and desired angles.
本研究为发展中地区的儿童提供了一种被动的、自驱动的、3D打印的柔性膝关节,以减少以上膝关节假体的总体费用,并增加在其生长周期中打印多个假体的便利性。提出了一种单片五杆机构设计,以提供足够的仿人步态,而不是以往刚性模型所提供的传统的腿式步态。这种步态是通过使用两种柔性链接以及一种新颖的3D打印方法来实现的,由于该机制的轻量级,这种方法更适合儿童。除了柔顺的膝关节外,柔顺的踝关节也被设计为在步态周期中提供所需的弯曲。使用完全被动膝关节的方法可以限制假体的重量,减轻儿童的负担,并隔离使用马达的需要。搭建了一个由齿条-小齿轮、两根平行杆、支架和两个伺服电机组成的试验台,对膝关节的性能进行了试验。虽然测试台是使用聚乳酸(PLA) 3D打印的,但柔性膝关节是用热塑性聚氨酯(TPU) 3D打印的,以模拟真实人类腿的手势。在Matlab Simscape中进行了仿真,验证了所提出的膝关节模拟了人类膝关节和所需角度。
{"title":"Preliminary Design and Experimental Studies of a Compliant Knee Joint for Pediatric Above Knee Amputees","authors":"Sahil Pitre, Bryan Curtin, P. Pena, Ciaphus Rouse, E. Joseph, Joshua Hooper, A. Tekes","doi":"10.1115/imece2021-73655","DOIUrl":"https://doi.org/10.1115/imece2021-73655","url":null,"abstract":"\u0000 This study presents a passive, self-actuated, 3D printed compliant knee joint for children in developing regions to decrease the overall expense of above knee prosthesis as well as increase the ease to print multiple prosthesis during their growing cycle. A single piece designed five-bar mechanism is proposed to provide adequate human-like gait instead of the traditional pegleg gait provided in previous rigid models. This gait is achieved through the use of both compliant links as well a novel 3D printed approach which is more accustomed to children because of the mechanism’s lightweight. In addition to the compliant knee joint, a compliant ankle possessing a flexure hinge placed at the toe is also designed to provide required bending during the gait cycle. The approach of using a fully passive knee joint enables to limit the weight of the prosthesis to create less of a burden to children and by isolating the need to utilize motors. A test bench consisted of a rack-pinion, two parallel rods, supports, and two servo motors are fabricated to experiment the performance of the knee joint. While the test bench is 3D printed using polylactic acid (PLA), the compliant knee joint is 3D printed in thermoplastic polyurethane (TPU) to emulate the gestures of a real human leg. Simulations are performed in Matlab Simscape to validate that the proposed knee joint mimics the human knee and desired angles.","PeriodicalId":314012,"journal":{"name":"Volume 5: Biomedical and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134325662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Volume 5: Biomedical and Biotechnology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1