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COVID-19 Screening in Rheumatologic Diseases Cases; Special Look at Chloroquine Derivate Use 风湿病病例COVID-19筛查研究特别关注氯喹衍生物的使用
Pub Date : 2021-12-15 DOI: 10.34172/hpr.2021.27
Soraya Shadmanfar, G. Alishiri, N. Bayat, M. Izadi, A. Salimzadeh, A. Rostamian, Shahla Abolghasemi, Mohammad Hossein Azimzadeh Ardebili, Zeynab Rastgar Moqaddam, M. Hasani, Ehsan Rahmanian, Helia Iranpanah, Ghodrat Allah Islami, A. Saburi
Background: Among suggested medications for the treatment of COVID-19, chloroquine derivates and angiotensin-converting– enzyme inhibitors (ACEIs)/angiotensin II type 1 receptor blockers (ARBs) are the two medications with conflicting effects on the development of the disease. Objectives: The present study aimed to evaluate COVID-19 in patients with rheumatic diseases receiving chloroquine derivate. Methods: Every patient with proven rheumatologic diseases registered in two referral centers in Tehran and Alborz, Iran was enrolled in the present descriptive cross-sectional study between May and June 2020. At first, the symptoms of COVID-19 were assessed, and if a case had suspicious symptoms, reverse transcription-polymerase chain reaction (RT-PCR) COVID-19 tests were done. Demographic and clinical data are documented for every patient. Then, the patients were grouped once according to their COVID-19 infection status and another time according to their hydroxychloroquine use. Results: 1159 patients enrolled in the study with a mean age of 49.39 years. Frequency of hypertension was 22.17 %, diabetics (9.49%) and 20 (1.7%) patients were positive for COVID-19 testing. The most common symptoms of the COVID-19 positive cases were cough (5.2%) and fever (4%). There was no significant difference in receiving ACEIs/ARBs or other medications between COVID-19 positive or negative patients. Among the patients receiving hydroxychloroquine, 15 patients (1.7%) had proved COVID-19 versus 5 patients (1.7%) who were not receiving these medications (P>0.999). Conclusion: The present study demonstrated that receiving ARBs or ACEIs was not different among patients with or without COVID-19. Moreover, receiving chloroquine derivate was not related to the development of COVID-19 in patients with rheumatologic disorders.
背景:在建议治疗COVID-19的药物中,氯喹衍生物和血管紧张素转换酶抑制剂(ACEIs)/血管紧张素II型1受体阻滞剂(ARBs)是两种对疾病发展的相互冲突的药物。目的:本研究旨在评估接受氯喹衍生物治疗的风湿病患者的COVID-19。方法:2020年5月至6月,在伊朗德黑兰和Alborz的两个转诊中心登记的所有确诊的风湿病患者都被纳入了本描述性横断面研究。首先评估新冠肺炎症状,如果出现可疑症状,进行逆转录聚合酶链反应(RT-PCR)检测。每个病人的人口统计和临床数据都有记录。然后根据患者的COVID-19感染情况分组一次,根据羟氯喹的使用情况分组一次。结果:1159例患者入组,平均年龄49.39岁。高血压患者占22.17%,糖尿病患者占9.49%,COVID-19检测阳性20例(1.7%)。新冠肺炎阳性病例最常见的症状是咳嗽(5.2%)和发烧(4%)。COVID-19阳性和阴性患者接受acei / arb或其他药物治疗的情况无显著差异。在接受羟氯喹治疗的患者中,确诊患者15例(1.7%),未接受羟氯喹治疗的患者5例(1.7%)(P>0.999)。结论:本研究表明,COVID-19患者接受arb或acei治疗的情况并无差异。此外,接受氯喹衍生物与风湿病患者的COVID-19发展无关。
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引用次数: 0
The Comparison Between the Early Tracheostomy and Orotracheal Intubation in COVID-19 Patients Required Mechanical Ventilation 需要机械通气的COVID-19患者早期气管切开与气管插管的比较
Pub Date : 2021-12-14 DOI: 10.34172/hpr.2021.26
Mahdi Morshedi, Mohammad-Javad Babaei, Ali Bahramifar, E. Karimi, S. Najafizadeh-Sari, M. Raei, Hamed Gholizadeh
Background: Supportive respiratory care and airway management are very important in treating COVID-19 patients with respiratory failure. There are two techniques for supporting patients with respiratory failure. Objectives: The current study aims to evaluate the efficacy and quality of patient care with early tracheostomy in intensive care unit (ICU) and compare mortality, hospital stay, and outcome between intubation and early tracheostomy. Methods: This study is conducted on total patients with confirmed COVID-19 in the ICU centers of a tertiary hospital. At the beginning of the study, all patients were intubated and connected to a mechanical ventilator. Within three days, the intensivists randomly performed bedside percutaneous dilational tracheostomy (PDT) for half of the patients. Early tracheostomy was defined as conducting tracheostomy within three days from intubation. Results: The total number of 36 patients was included in the study and categorized into two groups, including 18 patients in the early tracheostomy and 18 in orotracheal intubation. Half of the patients (50%) in the tracheostomy group were recovered from COVID-19 respiratory failure and discharged from ICU and hospital. All patients in the intubation group were expired. The length of staying alive in ICU in patients with an early tracheostomy was 26.47±3.79 compared with 7.58±2.36 days in intubated patients. Conclusion: The early tracheostomy compared with orotracheal intubation in respiratory failure patients with COVID-19 can significantly decrease mortality. However, airway management with an early tracheostomy increases the hospitalization stay and can increase recovery. So, conducting the early tracheostomy is recommended in this study.
背景:支持呼吸护理和气道管理在治疗新冠肺炎合并呼吸衰竭患者中非常重要。有两种技术可以支持呼吸衰竭患者。目的:本研究旨在评估重症监护病房(ICU)早期气管切开术患者的护理效果和质量,并比较插管和早期气管切开术的死亡率、住院时间和预后。方法:以某三级医院ICU收治的新冠肺炎确诊患者为研究对象。在研究开始时,所有患者均插管并连接机械呼吸机。在三天内,强化医师随机对一半的患者进行床边经皮扩张性气管切开术(PDT)。早期气管切开术定义为气管插管后3天内进行气管切开术。结果:共纳入36例患者,分为两组,早期气管切开18例,气管插管18例。气管切开术组患者中有一半(50%)从COVID-19呼吸衰竭中恢复并出院。插管组所有患者均已过期。早期气管切开术患者在ICU的生存时间为26.47±3.79天,插管患者为7.58±2.36天。结论:与经气管插管相比,早期气管切开治疗COVID-19呼吸衰竭患者可显著降低病死率。然而,气道管理与早期气管切开术增加住院时间,可以增加恢复。因此,本研究建议尽早行气管切开术。
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引用次数: 0
Perceived Discrimination and Suicidal Thoughts and Behaviors Among American African American and White Children 非裔美国人和白人儿童的感知歧视与自杀想法和行为
Pub Date : 2021-12-14 DOI: 10.34172/hpr.2021.28
S. Assari
Background: Perceived discrimination (PD) is a risk factor of suicidal thoughts and behaviors (STB) for children, youth, and adults. However, it is unknown whether the association between PD and STB frequency differs between African American (AA) and Non-Hispanic White children. Objectives: In this study, we compared AA and non-Latino White children for the association between PD and STB frequency in a national sample of 9-10-year-old American children. Methods: This cross-sectional study used data from the Adolescent Brain Cognitive Development (ABCD) study, which included 7883 non-Latino White or AA children between the ages of 9 and 10. The predictor variable was frequency of PDs. Race was the moderator. The outcome variable was STB frequency, treated as a count variable, reflecting positive STB items endorsed over the life-course. Covariates included sex, age, marital status, household income, parental education, parental employment, trauma, and economic difficulties. Poisson regression was used for data analysis. Results: Of all the participants, 5994 were non-Latino Whites, and 1889 were AAs. Overall, PD frequency was positively associated with STB frequency. A statistically significant interaction was found between race and PD, suggesting that the association between PD and STB frequency is weaker in AA than non-Latino White children. Conclusion: The observed weaker association between PDs frequency and STB frequency in AA than non-Latino White children suggests that PD may be a less salient risk factor of STB frequency for AA than non-Latino White children. Researchers should explore factors other than PD for suicide prevention of AA children in the US.
背景:感知歧视(PD)是儿童、青少年和成人自杀念头和行为(STB)的一个危险因素。然而,尚不清楚PD与STB频率之间的关系在非裔美国人(AA)和非西班牙裔白人儿童中是否有所不同。目的:在本研究中,我们比较了AA和非拉丁裔白人儿童在9-10岁美国儿童的PD和STB频率之间的关系。方法:这项横断面研究使用了青少年大脑认知发展(ABCD)研究的数据,其中包括7883名年龄在9至10岁之间的非拉丁裔白人或AA儿童。预测变量为PDs的发生频率。种族是调解人。结果变量为STB频率,作为计数变量,反映生命过程中认可的阳性STB项目。协变量包括性别、年龄、婚姻状况、家庭收入、父母教育程度、父母就业、创伤和经济困难。采用泊松回归进行数据分析。结果:所有参与者中,5994人为非拉丁裔白人,1889人为AAs。总体而言,PD频率与STB频率呈正相关。种族与PD之间存在统计学上显著的相互作用,表明AA儿童中PD与STB频率之间的关联弱于非拉丁裔白人儿童。结论:与非拉丁裔白人儿童相比,斑马病发生频率与斑马病发生频率之间的相关性较弱,提示斑马病可能是斑马病发生频率较不显著的危险因素。研究人员应该探索PD以外的因素来预防美国嗜酒成瘾儿童的自杀。
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引用次数: 0
Introducing a Bi-Level Linear Programming Model to Reduce Patient Payment and Increase Hospital Income Simultaneously 引入双层线性规划模型,减少患者支付,同时增加医院收入
Pub Date : 2021-12-07 DOI: 10.34172/hpr.2021.29
S. F. Tayebnasab, M. Rahdar, Farhad Hamidi, H. Maleki
Background: The cost of health care is a large part of every household’s budget. On the other hand, as an economic entity, the hospital is constantly faced with different aspects of cost and revenue. So, we are dealing with conflicting objectives. Objectives: The main purpose of the research is to help financial management in a specialty hospital. This article provides part of operational research under bi-level optimization for hospital managers to provide targeted financial planning. The method is based on the fact that the objective is to maximize the hospital income on one level, and on the other level, the objective is to reduce the patient’s payment. Methods: The hierarchical and decentralized optimization problem is written as a bi-level model that minimizes patient costs and maximizes hospital revenues, which is an NP-Hard problem. The optimal solution to this problem is obtained using a genetic algorithm. Then, the hospital’s performance is evaluated by the Pabon Lasso diagram. It is shown that the use of this model has a significant effect on the hospital’s performance. Results: Implementation of this model in the studied hospital shows that patient payment costs decreased and hospital income increased (reaching equilibrium point). Conclusion: Hospital performance after model implementation was evaluated by the Pabon Lasso diagram and showed that it has an effective role in hospital performance.
背景:医疗保健费用占每个家庭预算的很大一部分。另一方面,医院作为一个经济实体,不断面临着成本和收入的不同方面。所以,我们在处理相互矛盾的目标。目的:研究的主要目的是为专科医院的财务管理提供帮助。本文提供了双层优化下的部分运筹学研究,为医院管理者提供有针对性的财务规划。该方法基于这样一个事实,即目标是在一个层面上使医院收入最大化,而在另一个层面上,目标是减少患者的支付。方法:将分层分散优化问题写成患者成本最小化和医院收益最大化的双层模型,这是一个NP-Hard问题。利用遗传算法得到了该问题的最优解。然后,采用Pabon Lasso图对医院绩效进行评价。结果表明,该模型的使用对医院绩效有显著影响。结果:该模型在研究医院的实施表明,患者支付成本下降,医院收入增加(达到平衡点)。结论:采用Pabon Lasso图对模型实施后的医院绩效进行评价,表明模型对医院绩效有有效的影响。
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引用次数: 0
The Anti-inflammatory Role of Curcumin in Osteoarthritis: An Overview of Molecular and Radiologic Changes 姜黄素在骨关节炎中的抗炎作用:分子和放射学变化综述
Pub Date : 2021-12-01 DOI: 10.34172/hpr.2022.01
Reza Gerami, Ramezan Jafari, Niloufar Nazeri, A. Saburi
Osteoarthritis (OA) is the most common form of arthritis, causing pain and progressive disability in millions of people worldwide. The commonly prescribed medications for OA, including non-steroidal anti-inflammatory drugs, have many side effects which has led the scientists to consider safer drugs as an alternative. Therapeutic effects of Curcumin on OA are increasingly declared, and its various aspects in suppressing inflammation and reducing the disease progression are examined more thoroughly. This study aims to discuss curcumin and OA to help scientists working in these fields. In this brief review, we took a look at OA pathogenesis, the role of the immune system, and the biomarkers involved in the onset and progression of the disease. We focused on available data on the anti-inflammatory effect and mechanism of treatment by curcumin on OA.
骨关节炎(OA)是最常见的关节炎形式,在全世界数百万人中引起疼痛和进行性残疾。治疗OA的常用处方药,包括非甾体抗炎药,有许多副作用,这使得科学家们考虑使用更安全的药物作为替代。姜黄素对OA的治疗作用被越来越多地宣布,其在抑制炎症和减缓疾病进展方面的各个方面被更深入地研究。本研究旨在探讨姜黄素与OA的关系,以帮助在这些领域工作的科学家。在这篇简短的综述中,我们探讨了OA的发病机制、免疫系统的作用以及与疾病发生和发展有关的生物标志物。我们着重于现有的姜黄素对OA的抗炎作用和治疗机制的研究。
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引用次数: 0
Increased Incidence of Blood and Body Fluid Exposure and Lack of Transmission Evidence During COVID-19 Pandemic COVID-19大流行期间血液和体液暴露发生率增加以及缺乏传播证据
Pub Date : 2021-11-22 DOI: 10.34172/hpr.2021.31
H. Guanche Garcell, A. V. Arias
Background: Coronavirus disease 2019 (COVID-19) pandemic has been associated with various risks, including the exposure of infectious agents. Objectives: The study aims at describing the incidence of blood and body fluid (BBF) exposure in a COVID-19 facility so as viral transmission potential through blood. Methods: A descriptive study of BBF exposure notified was carried out in a community hospital in Qatar. Results: In 2020, 29 needlesticks injuries were reported, which is a significant increase compared to the year 2019 (6 incidents) and 2018 (5 incidents). No evidence of SARS-CoV-2 transmission was shown concerning the injury using symptoms monitoring and lab test. Conclusion: The increased risk of BBF exposure during the pandemic provides insight into the need to review the prevention practices of occupational exposure during pandemics. Additional studies are required to define the risk of COVID-19 related to occupational exposure to BBF.
背景:2019冠状病毒病(COVID-19)大流行与各种风险相关,包括接触传染原。目的:本研究旨在描述COVID-19设施中血液和体液(BBF)暴露的发生率,以及病毒通过血液传播的可能性。方法:在卡塔尔一家社区医院对通报的BBF暴露进行描述性研究。结果:2020年,29针头伤亡报告,这是一个显著增加相比,2019年(6事件)和2018年(5事件)。通过症状监测和实验室检测,未发现与损伤有关的SARS-CoV-2传播证据。结论:大流行期间BBF暴露风险的增加使人们认识到有必要审查大流行期间职业暴露的预防措施。需要进一步的研究来确定与职业暴露于BBF相关的COVID-19风险。
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引用次数: 0
Managing Neurosurgery in the Covid-19 Pandemic 在Covid-19大流行中管理神经外科
Pub Date : 2021-11-08 DOI: 10.21203/rs.3.rs-955198/v1
Bahram Aminmansour, Mehdi Mahmoudkhani, Mehdi Shafiei, M. Sabouri, M. Hematzadeh, D. Tehrani
BackgroundCovid-19 quickly spread around the world as an epidemic with potentially unknown hazards. Like its impacts on various occupations, neurosurgery has undergone changes due to the virus, including changes in surgical planning, inpatient and outpatient clinics, emergency management, and even academic activities. The present study was performed to determine neurosurgery challenges during the Covid-19 pandemic in Iran.MethodsThe present study was conducted as a mixed qualitative and quantitative study in 2021. In the qualitative section using the targeted sampling method, 11 members of the target community were selected using the available sampling method and completed a questionnaire. The qualitative part was conducted in two stages of reviewing texts and interviewing experts and in the quantitative part we evaluated the validity of the structure and the reliability of the questionnaire.ResultsThis study examined in detail all aspects of the effects of Covid-19 on neurosurgery. 9 dimensions and 61 items were identified as the challenges of neurosurgery during the Covid-19 pandemic. In order of importance, the aspects were: treatment outcome, manpower, management psychological and physical diseases, education and research, tools and physical space, ethics, financial implications and information technology.ConclusionThe outbreak of epidemics has different risks for specialties, among them neurosurgery. Accordingly, to observe patients' right to treatment, all necessary measures were first taken to provide instructions, regulations, policies and ethical guidelines.
作为一种具有潜在未知危害的流行病,covid -19迅速在全球蔓延。就像它对各种职业的影响一样,神经外科也因病毒而发生了变化,包括手术计划、住院和门诊诊所、急诊管理甚至学术活动的变化。本研究旨在确定伊朗Covid-19大流行期间神经外科面临的挑战。方法本研究于2021年进行定性和定量混合研究。在定性部分,采用目标抽样方法,选取目标社区的11名成员,完成问卷调查。定性部分分为文本审阅和专家访谈两个阶段进行,定量部分对问卷结构的效度和信度进行评估。结果本研究详细检查了新冠肺炎对神经外科的各个方面的影响。确定新冠肺炎大流行期间神经外科面临的挑战为9个维度、61个项目。按重要性排列的方面是:治疗结果、人力、心理和身体疾病的管理、教育和研究、工具和物理空间、伦理、财务影响和信息技术。ConclusionThe流行病的爆发对专科有不同的风险,其中包括神经外科。因此,为了尊重病人接受治疗的权利,首先采取一切必要措施,提供指示、条例、政策和道德准则。
{"title":"Managing Neurosurgery in the Covid-19 Pandemic","authors":"Bahram Aminmansour, Mehdi Mahmoudkhani, Mehdi Shafiei, M. Sabouri, M. Hematzadeh, D. Tehrani","doi":"10.21203/rs.3.rs-955198/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-955198/v1","url":null,"abstract":"\u0000 BackgroundCovid-19 quickly spread around the world as an epidemic with potentially unknown hazards. Like its impacts on various occupations, neurosurgery has undergone changes due to the virus, including changes in surgical planning, inpatient and outpatient clinics, emergency management, and even academic activities. The present study was performed to determine neurosurgery challenges during the Covid-19 pandemic in Iran.MethodsThe present study was conducted as a mixed qualitative and quantitative study in 2021. In the qualitative section using the targeted sampling method, 11 members of the target community were selected using the available sampling method and completed a questionnaire. The qualitative part was conducted in two stages of reviewing texts and interviewing experts and in the quantitative part we evaluated the validity of the structure and the reliability of the questionnaire.ResultsThis study examined in detail all aspects of the effects of Covid-19 on neurosurgery. 9 dimensions and 61 items were identified as the challenges of neurosurgery during the Covid-19 pandemic. In order of importance, the aspects were: treatment outcome, manpower, management psychological and physical diseases, education and research, tools and physical space, ethics, financial implications and information technology.ConclusionThe outbreak of epidemics has different risks for specialties, among them neurosurgery. Accordingly, to observe patients' right to treatment, all necessary measures were first taken to provide instructions, regulations, policies and ethical guidelines.","PeriodicalId":32113,"journal":{"name":"Hospital Practices and Research","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82714259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptomatology, Positivity, and Type of Care Received by Healthcare Workers Tested for COVID-19 Infection in a North-Central State in Nigeria: A Retrospective Study 尼日利亚中北部一个州进行COVID-19感染检测的医护人员的症状、阳性反应和接受的护理类型:一项回顾性研究
Pub Date : 2021-10-30 DOI: 10.34172/hpr.2021.25
O S Ilesanmi, A. Afolabi, O. D. Awoyale, O. Fakayode
Background: The health of healthcare workers (HCWs) is an indicator of the quality of health service provision during the COVID-19 pandemic. Objectives: This study aimed to describe the symptomatology and positivity of COVID-19 infection and the type of COVID-19 care received among HCWs in a North-Central State in Nigeria. Methods: This was a retrospective review of HCWs tested for COVID-19 as retrieved from the Surveillance Outbreak Response Management System between April 2020 and March 2021 in Kwara State, Nigeria. Results: Among the 1453 HCWs, 831 (57.2%) were above 35 years, and 874 (60.2%) were females. Among the 259 HCWs who tested positive for COVID-19, 122 (23.8%) lived in urban areas (χ2=13.94, P≤0.001). Also, 83 (30.7%) of symptomatic persons tested positive for COVID-19 (χ 2=37.766, P≤0.001). Overall, 33 (12.7%) of the 259 positive HCWs received hospital-based COVID-19 care, and 33 (16.1%) who had less than 2 symptoms received hospital-based COVID-19 care (χ2=9.962, P=0.002). HCWs who had cough had three times odds of testing positive for COVID-19 (OR=3.299, 95% CI=1.571–6.927, P=0.002). Also, HCWs who manifested loss of taste had three times odds of testing positive for COVID-19 (OR=3.392, 95% CI=1.010–11.393, P=0.048). Conclusion: COVID-19 testing should be encouraged among HCWs, especially those with cough symptoms and loss of taste.
背景:卫生保健工作者(HCWs)的健康状况是COVID-19大流行期间卫生服务提供质量的一项指标。目的:本研究旨在描述尼日利亚中北部一个州卫生保健工作者中COVID-19感染的症状和阳性情况以及所接受的COVID-19护理类型。方法:对尼日利亚夸拉州2020年4月至2021年3月监测疫情应对管理系统中检测COVID-19的卫生保健工作者进行回顾性分析。结果:1453名卫生保健员中,35岁以上831人(57.2%),女性874人(60.2%)。在COVID-19检测阳性的259名卫生保健工作者中,有122名(23.8%)生活在城市地区(χ2=13.94, P≤0.001)。有症状者中有83例(30.7%)新冠病毒检测呈阳性(χ 2=37.766, P≤0.001)。总体而言,259例阳性HCWs中有33例(12.7%)接受了基于医院的COVID-19护理,症状少于2例的33例(16.1%)接受了基于医院的COVID-19护理(χ2=9.962, P=0.002)。咳嗽的医护人员COVID-19检测阳性的几率为3倍(OR=3.299, 95% CI= 1.571-6.927, P=0.002)。此外,表现出味觉丧失的医护人员在COVID-19检测中呈阳性的几率是其三倍(OR=3.392, 95% CI= 1.010-11.393, P=0.048)。结论:应鼓励医护人员进行COVID-19检测,特别是有咳嗽症状和味觉丧失的医护人员。
{"title":"Symptomatology, Positivity, and Type of Care Received by Healthcare Workers Tested for COVID-19 Infection in a North-Central State in Nigeria: A Retrospective Study","authors":"O S Ilesanmi, A. Afolabi, O. D. Awoyale, O. Fakayode","doi":"10.34172/hpr.2021.25","DOIUrl":"https://doi.org/10.34172/hpr.2021.25","url":null,"abstract":"Background: The health of healthcare workers (HCWs) is an indicator of the quality of health service provision during the COVID-19 pandemic. Objectives: This study aimed to describe the symptomatology and positivity of COVID-19 infection and the type of COVID-19 care received among HCWs in a North-Central State in Nigeria. Methods: This was a retrospective review of HCWs tested for COVID-19 as retrieved from the Surveillance Outbreak Response Management System between April 2020 and March 2021 in Kwara State, Nigeria. Results: Among the 1453 HCWs, 831 (57.2%) were above 35 years, and 874 (60.2%) were females. Among the 259 HCWs who tested positive for COVID-19, 122 (23.8%) lived in urban areas (χ2=13.94, P≤0.001). Also, 83 (30.7%) of symptomatic persons tested positive for COVID-19 (χ 2=37.766, P≤0.001). Overall, 33 (12.7%) of the 259 positive HCWs received hospital-based COVID-19 care, and 33 (16.1%) who had less than 2 symptoms received hospital-based COVID-19 care (χ2=9.962, P=0.002). HCWs who had cough had three times odds of testing positive for COVID-19 (OR=3.299, 95% CI=1.571–6.927, P=0.002). Also, HCWs who manifested loss of taste had three times odds of testing positive for COVID-19 (OR=3.392, 95% CI=1.010–11.393, P=0.048). Conclusion: COVID-19 testing should be encouraged among HCWs, especially those with cough symptoms and loss of taste.","PeriodicalId":32113,"journal":{"name":"Hospital Practices and Research","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86706443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Transcranial Direct Current Stimulation on Patients With Parkinson’s disease: A Report of 2 Cases 经颅直流电刺激治疗帕金森病2例报告
Pub Date : 2021-10-11 DOI: 10.34172/hpr.2021.32
R. Bidaki, H. Mirhosseini, Nahid Zare
Introduction: The motor function is associated with the activity of both the motor and prefrontal cortices. The efficacy of transcranial direct current stimulation (tDCS) over specific brain cortices has been examined in many psychiatric and neurologic disorders. This study aims to report the tDCS effects on two females of advanced age with idiopathic Parkinson’s disease (PD). Case Presentation: We considered 50-minute sessions of bilateral primary motor cortices and left dorsolateral prefrontal cortex (DLPFC) anodal stimulation using tDCS with passive stretching exercises simultaneously for a total of 20 sessions in 7 weeks. Clinical signs and electroencephalography (EEG) waveform were assessed at distinct times. Both of the two patients showed improved motor function for a short time. EEG changes to some extent concerned clinical states. Conclusion: It seems that tDCS can be an auxiliary treatment for motor dysfunction in PD; however, further studies must be carried out to prove the claim.
运动功能与运动皮质和前额叶皮质的活动有关。经颅直流电刺激(tDCS)对特定大脑皮层的疗效已经在许多精神和神经疾病中得到了检验。本研究旨在报道tDCS对2例高龄特发性帕金森病(PD)女性患者的影响。病例介绍:我们考虑了50分钟的双侧初级运动皮层和左背外侧前额叶皮层(DLPFC)阳极刺激,同时使用tDCS和被动拉伸练习,在7周内共进行20次。在不同时间评估临床症状和脑电图(EEG)波形。两例患者均在短时间内表现出运动功能的改善。脑电图变化在一定程度上关系到临床状态。结论:tDCS可作为PD患者运动功能障碍的辅助治疗方法;然而,必须进行进一步的研究来证明这一说法。
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引用次数: 0
Evaluation of Patients Presenting to the Emergency Department With Chronic Pain: An Observational Clinical Study 急诊慢性疼痛患者评估:一项观察性临床研究
Pub Date : 2021-10-11 DOI: 10.34172/hpr.2021.30
Tuba Erdem Sultanoğlu, Hasan Sultanoğlu
Background: Overcrowding of emergency departments (EDs), which are not suitable places to treat chronic pain and are responsible for managing acute disorders, leads to prolonged waiting times, delays in treating conditions requiring rapid intervention, patient dissatisfaction, and chaos and exhaustion in the ED. Objectives: Examine the characteristics of patients who presented to the ED with non-malignant chronic pain to determine the frequency of use and factors that caused ED use. Methods: This cross-sectional study was conducted in an ED. Three hundred ninety-two patients with chronic pain were included. Results: The mean age of the patients was 48.1±15.3 years, 62.2% were female, and 37.8% were male. Of the patients, 59.2% were married, 42.6% had elementary school education, and 56.1% were unemployed. The most common cause of ED admission was low back pain (LBP), the 32.7% used non-steroidal anti-inflammatory drugs, 16.3% used opioid analgesics, 15.8% used anticonvulsants, 13.2% used anticonvulsants antidepressant drugs, 22% did not use any medication. The reasons for presenting to the ED for chronic pain were 13.3% for medication prescription, 74.5% for receiving analgesics, and 12.2% for a diagnosis. The mean Patient Health Questionnaire-9 (PHQ-9) scale score of the participants was 12.82±3.98, which indicated moderate depressive symptoms. The mean Generalized Anxiety Disorder-7 scale score was 9.84±3.23, which indicated mild generalized anxiety disorder. Conclusion: Instead of trying to suppress pain, emphasis should be put on preventing overcrowding in EDs, which are intended to manage acute conditions rather than chronic pain, informing patients about the methods of coping with pain, increasing their quality of life, and integrating them into social life.
背景:急诊科(ED)人满为患,不适合治疗慢性疼痛和负责管理急性疾病,导致等待时间延长,治疗需要快速干预的疾病延误,患者不满,以及急诊室混乱和疲惫。目的:研究到ED就诊的非恶性慢性疼痛患者的特征,以确定使用频率和导致使用ED的因素。方法:本横断面研究在急诊科进行,包括392例慢性疼痛患者。结果:患者平均年龄48.1±15.3岁,女性占62.2%,男性占37.8%。59.2%的患者已婚,42.6%的患者受过小学教育,56.1%的患者无业。最常见的ED入院原因是腰痛(LBP), 32.7%使用非甾体类抗炎药,16.3%使用阿片类镇痛药,15.8%使用抗惊厥药,13.2%使用抗惊厥药抗抑郁药,22%未使用任何药物。到急诊科就诊的慢性疼痛患者中,13.3%是因为药物处方,74.5%是因为接受止痛药治疗,12.2%是因为诊断。患者健康问卷-9 (PHQ-9)平均得分为12.82±3.98分,为中度抑郁症状。广泛性焦虑障碍-7量表平均得分为9.84±3.23,为轻度广泛性焦虑障碍。结论:应重视预防急诊科过度拥挤,而不是试图抑制疼痛。急诊科是治疗急症而非慢性疼痛的科室,应告知患者应对疼痛的方法,提高患者的生活质量,使其融入社会生活。
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引用次数: 0
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