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Fungi: The budding source for biomaterials 真菌:生物材料的萌芽来源
Pub Date : 2021-06-01 DOI: 10.21608/mb.2021.92305.1038
S. Mandal, R. Krishnan
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引用次数: 0
The role of endophytic fungi in combating abiotic stress on tomato 内生真菌在番茄抗非生物胁迫中的作用
Pub Date : 2021-01-01 DOI: 10.21608/mb.2021.91779.1037
Ahmed Abo Nouh, Fatma A. Abo Nouh, Abdelghafar M. Abu-Elsaoud, Ahmed M. Abdel-Azeem
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引用次数: 5
SARS‑CoV‑2 mutation hotspots incidence in different geographic regions SARS - CoV - 2突变热点在不同地理区域的发病率
Pub Date : 2020-12-03 DOI: 10.21608/mb.2020.46676.1026
J. Ahmad, G. Tayib, T. Mohamed
ABSTRACT SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) is RNA virus with a positive-sense single-strand that belongs to the beta-coronavirus group that causes COVID-19 (Coronavirus Disease 2019) which originally emerged in China. Viruses with RNA genomes are known by a high mutation rate potential. The mutation rate determines genome variability and evolution of the virus; therefore, allowing viruses to evade the immune system, gain more infectivity potentials, virulence modifications, and probably resistance development to antivirals. A total of 311 SARS-CoV-2 virus whole genome sequences have been retrieved from the GISAID database from 1st of January 2020 to 31th of August 2020. The sequences were analyzed for sequence purity and multiple sequence alignment together with reference sequence was conducted through using Clustal Omega that is imbedded in Jalview software and Blast tools. We recorded the occurrence of 4 newly incident high frequently occurring mutations in all six geographic regions, namely at positions 2416, 18877, 23401, and 27964. The majority of all recorded hotspots were detected in Asia, Europe, and North America. The findings of our study suggest that the SARS-CoV-2 is in continuous evolution. For the impact of these mutations, further investigations are required and to understand whether these mutations would lead to the appearance of Drug-resistance viral strains, strains with increased infectivity and pathogenicity, and also their effect on the vaccine development and immunogenesis.
SARS-CoV-2(严重急性呼吸综合征冠状病毒2)是一种具有正义单链的RNA病毒,属于引起COVID-19(冠状病毒病2019)的β冠状病毒群,最初在中国出现。具有RNA基因组的病毒具有较高的突变率潜力。突变率决定了病毒的基因组变异和进化;因此,允许病毒逃避免疫系统,获得更多的传染性潜力,毒力改变,并可能对抗病毒药物产生耐药性。从2020年1月1日至2020年8月31日的GISAID数据库中检索到311个SARS-CoV-2病毒全基因组序列。利用嵌入在Jalview软件和Blast工具中的Clustal Omega对序列进行纯度分析,并与参考序列进行多序列比对。在所有6个地理区域中,分别在2416、18877、23401和27964位点记录到了4个新发生的高频率突变。在所有记录的热点中,大多数在亚洲、欧洲和北美被发现。我们的研究结果表明,SARS-CoV-2处于持续进化中。对于这些突变的影响,需要进行进一步的调查,以了解这些突变是否会导致耐药病毒株的出现,这些病毒株具有更高的传染性和致病性,以及它们对疫苗开发和免疫发生的影响。
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引用次数: 5
Mycotoxins and cancer 霉菌毒素与癌症
Pub Date : 2020-06-01 DOI: 10.21608/mb.2020.99588
Doaa E. Elmetwally
Ingestion of food is the major route of human exposure to chemical and biological contaminants, especially mycotoxins. Food additives have been used throughout history to perform specific functions in foods.
食物摄入是人类接触化学和生物污染物,特别是真菌毒素的主要途径。食品添加剂在历史上一直被用来在食品中发挥特定的功能。
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引用次数: 0
Lichens in folklore: medicine and dyes 民间传说中的地衣:医药和染料
Pub Date : 2020-06-01 DOI: 10.21608/mb.2020.99386
A. Abdel-Fattah
Lichens were mentioned in folklore of different cultures around the world for its ability to treat several diseases; thus, it has been used in folk medicine. Lichens were believed to be useful in the treatment of wounds, skin diseases, gastrointestinal and respiratory problems. It has been reported that lichens characterized by high carbohydrate storage, contain several secondary bioactive metabolites that act as antibiotics. Lichens were used topically as wound disinfectants, anti-bleeding, other skin problems such as soreness and mouth infections. According to Müller (2002), lichen metabolites possess a wide range of biologically active compounds with antibiotic, antifungal, antiviral, anti-inflammatory, analgesic, antipyretic, antitumor, immunomodulation and cytotoxic potentials. Despite of these different activities of lichen metabolites, their therapeutic potentials have not fully investigated yet and remain pharmaceutically untapped. We can conclude the importance of lichens usage from the word leikhēn, "what eats around itself", which derived from ancient Greek custom of using a cryptogam to treat skin disorders. Lichens are often drunk as a decoction for treating lung or digestive-related ailments. Many other lichens uses related to obstetrics or the treatment of gynecological problems. This may be due to the widespread utilization of lichens to cure infections that transmitted sexually and urinary system disorders. In many different cultures, there are other uses of lichens for the treatment of eye afflictions, the treatment of feet problems and the use of smoking mixtures. Usnea is the most commonly used genus of lichen, however it is often used synonymously with other arboreal hair lichen. Usnea is a long, pendulous and hair like species used for scalp disorders and hair reinforcement.
地衣在世界各地不同文化的民间传说中都被提及,因为它能治疗几种疾病;因此,它已被用于民间医学。地衣被认为对治疗伤口、皮肤病、胃肠道和呼吸系统疾病有用。据报道,地衣具有高碳水化合物储存的特点,含有几种次生生物活性代谢物,可作为抗生素。地衣被局部用于伤口消毒、止血、其他皮肤问题,如疼痛和口腔感染。根据m ller(2002)的研究,地衣代谢物具有广泛的生物活性化合物,具有抗生素、抗真菌、抗病毒、抗炎、镇痛、解热、抗肿瘤、免疫调节和细胞毒性潜能。尽管地衣代谢物具有这些不同的活性,但它们的治疗潜力尚未得到充分的研究,并且在药学上尚未开发。我们可以从单词leikhēn(“吃自己周围的东西”)中得出地衣使用的重要性,该单词源于古希腊使用cryptogam治疗皮肤病的习俗。地衣常被当作治疗肺部或消化系统疾病的汤剂饮用。地衣的许多其他用途与产科或妇科问题的治疗有关。这可能是由于地衣广泛用于治疗传播性和泌尿系统疾病的感染。在许多不同的文化中,地衣还有其他用途,用于治疗眼部疾病、脚部问题和吸烟混合物。Usnea是最常用的地衣属,但它通常与其他树栖毛地衣同义使用。Usnea是一种长,下垂和毛发状的物种,用于头皮疾病和头发加固。
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引用次数: 0
Jean Mouchacca: The mycologist and Ramesses II’s mummy Jean Mouchacca:真菌学家和拉美西斯二世的木乃伊
Pub Date : 2020-06-01 DOI: 10.21608/mb.2020.99951
Mohamed Wael Abd El-Azeem
Finding the cause of the deterioration and arresting it were imperatives in the study. From among the wrappings, minute samples of the mummy’ chest and hair were taken for analysis. Mouchacca succeeded in identifying the destructive organism – a fungus with the splendid name Daedalea biennis (Bull.) Fr.
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引用次数: 0
Checklist of Algerian fungi – Part 4: Sordariomycetes (Ascomycota) 阿尔及利亚真菌清单第4部分:sordariomycates(子囊菌科)
Pub Date : 2019-12-21 DOI: 10.21608/mb.2019.65799
Amrani, A. Nahas, Amal S. Abdel-Azeem
A checklist is presented of ascomycetes belonging to class Sordariomycetes in Algeria. This group of fungi is represented in the country by at least 189 genera and 470 species. The list is based on bibliographical, thesis and herbaria online databases sources. This checklist is the first comprehensive species list fully dedicated to Algerian Sordariomycetes.
本文介绍了阿尔及利亚属于索达菌纲的子囊菌清单。这类真菌在该国至少有189属470种。该列表基于书目、论文和植物标本馆在线数据库资源。这份清单是第一个全面的物种清单,完全致力于阿尔及利亚索达利菌。
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引用次数: 1
Fungal conservation and ancient Egyptians- Part 2: A spiritual heritage of a look 真菌保护和古埃及-第2部分:一种精神遗产的外观
Pub Date : 2019-10-15 DOI: 10.21608/mb.2019.59424
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引用次数: 0
Forouzan R. Shafie
Pub Date : 2019-08-01 DOI: 10.21608/mb.2019.44653
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引用次数: 0
Fungal conservation and ancient Egyptians- Part 1: A spiritual heritage of a look 真菌保护和古埃及-第1部分:一种精神遗产的外观
Pub Date : 2019-08-01 DOI: 10.21608/mb.2019.44738
F. Shafie
Egypt is the cradle of civilization and mycology. Drawing fungi is one of the joys of mycology, and something that anybody can try. Art has been a part of mycology since earliest times and published in many international journals and books. Line drawings are essential for showing details of fungal structure, whether in a field guide or fungal monographs. Ancient Egyptians produced a number of hieroglyphic depictions of psychedelic mushrooms on temples and through hieroglyphic texts throughout the country. A new attractive tool to raise national and international awareness on fungal conservation is drawing of fungi in many attractive portraits as ancient Egyptians documented them everywhere. In this series of paintings I participated with these portraits to attract young mycologists in MENA and to apply a new tool for conserving fungi.
埃及是文明和真菌学的摇篮。绘制真菌是真菌学的乐趣之一,也是任何人都可以尝试的事情。艺术自古以来就是真菌学的一部分,并在许多国际期刊和书籍中发表。无论是在野外指南还是真菌专著中,线条图对于显示真菌结构的细节都是必不可少的。古埃及人在庙宇上和全国各地的象形文字中制作了许多迷幻蘑菇的象形文字描述。一个新的有吸引力的工具来提高国家和国际上对真菌保护的认识是在许多有吸引力的肖像中绘制真菌,因为古埃及人到处记录它们。在这一系列的绘画中,我参与了这些肖像,以吸引中东和北非地区的年轻真菌学家,并应用一种新的工具来保存真菌。
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引用次数: 0
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Microbial Biosystems Journal
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