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Celiac plexus chemical neurolysis for refractory pain associated with superior mesenteric artery syndrome 腹腔丛化学神经松解术治疗与肠系膜上动脉综合征相关的难治性疼痛
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_25_22
R. Sharma, Ajit Kumar, Girish Singh, S. Goyal, Suyashi Sharma
Superior mesenteric artery (SMA) syndrome is caused by the compression of a part of the intestine between the aorta and SMA. It may lead to severe epigastric pain that is even refractory to conservative and surgical forms of therapy. Celiac plexus chemical neurolysis has been used in the past for debilitating pain associated with upper gastrointestinal malignancies and chronic pancreatitis. However, to date, this intervention has never been described in the literature for managing pain in SMA syndrome patients. Here, we describe the case of SMA syndrome whose pain was successfully managed with celiac plexus chemical neurolysis.
肠系膜上动脉(SMA)综合征是由主动脉和SMA之间的肠道部分受压引起的。它可能会导致严重的上腹部疼痛,甚至是保守和手术治疗难以治愈的。腹腔神经丛化学神经松解术过去曾用于治疗与上消化道恶性肿瘤和慢性胰腺炎相关的衰弱性疼痛。然而,到目前为止,文献中从未描述过这种干预措施来治疗SMA综合征患者的疼痛。在这里,我们描述了SMA综合征的病例,其疼痛通过腹腔丛化学神经松解术成功控制。
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引用次数: 0
Ultrasonography-guided hydrodissection using platelet-rich plasma or corticosteroid in adhesive capsulitis of the shoulder: A comparative study 超声引导下应用富含血小板血浆或皮质类固醇的水下剥离术治疗肩关节粘连性囊炎的比较研究
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_4_22
Iqra Mehak, Aftab Hussain, H. Usmani, S. Amir
Background: Adhesive capsulitis is a condition that presents with pain and progressive limitation of both active and passive shoulder movements. It can be primary or secondary, the latter includes causes such as rotator cuff tear, cardiovascular disease, and diabetes mellitus. The American Shoulder and Elbow Surgeons defines that adhesive capsulitis is a condition of uncertain ethology characterized by a significant restriction of both active and passive shoulder motions that occur in the absence of known intrinsic shoulder disorder. Commonly described as: Stage 1 – Freezing stage, with pain and stiffness lasting around 9 months. Stage 2 – Frozen stage, with persistent stiffness lasting 4–12 months. Stage 3 – Thawing stage, with spontaneous recovery lasting 12–42 months. Ultrasonography (USG)-guided hydrodissection is used for adhesive capsulitis of the shoulder due to its cost-effectiveness and acceptance among patients. As adhesive capsulitis is postulated as an i nflammatory and fibrotic disease, easy treatment with intra-articular corticosteroids (CSs) injection may reduce synovitis, limit the development of capsular fibrosis, and alter the natural history of disease. CS injections are effective for shorter duration, but newer agents such as platelet-rich plasma (PRP) are more effective with no serious side effects. Materials and Methods: In this study, 40 patients were taken of adhesive capsulitis of the shoulder and were divided randomly into two groups. One group received injection PRP and the other group received injection CS. The outcome was recorded. Results: There was a statistically significant reduction in numeric rating scale pain scores in both the groups over a time period of 6 weeks, but the PRP injection was observed to be better in reducing the pain scores when compared to the CS injection after the 6th week (P = 0.037). Initially, the CS injection performed better in the 1st week due to anti-inflammatory action. By the 3rd week, both the injections showed a similar effect. However, at the end of the study period (6 weeks), there was a better reduction in the Shoulder Pain and Disability Index (SPADI) pain scores (P = 0.0057) and SPADI disability scores (P = 0.029) of the group PRP. Conclusion: We concluded that USG-guided hydrodissection with PRP is more effective therapy than CS in terms of reduction of pain and improvement in shoulder function in the treatment of adhesive capsulitis of shoulder.
背景:粘连性囊炎是一种表现为疼痛和主动和被动肩部运动逐渐受限的疾病。它可以是原发性的,也可以是继发性的,后者包括肩袖撕裂、心血管疾病和糖尿病等原因。美国肩肘外科医生定义,粘连性囊炎是一种行为学不确定的疾病,其特征是在没有已知内在肩部疾病的情况下,主动和被动肩部运动都受到显著限制。通常描述为:第1阶段-冷冻阶段,疼痛和僵硬持续约9个月。第2阶段-冰冻期,持续僵硬持续4-12个月。第3阶段–解冻阶段,自发恢复持续12–42个月。超声(USG)引导下的水下剥离术因其成本效益和患者接受度而被用于肩部粘连性囊炎。由于粘连性囊炎被认为是一种炎症和纤维化疾病,关节内皮质类固醇(CS)注射的简单治疗可以减少滑膜炎,限制囊纤维化的发展,并改变疾病的自然史。CS注射有效期较短,但较新的药物,如富血小板血浆(PRP)更有效,没有严重副作用。材料与方法:本研究选取40例肩关节粘连性囊炎患者,随机分为两组。一组接受PRP注射,另一组接受CS注射。记录结果。结果:在6周的时间里,两组的数字评分量表疼痛评分都有统计学上的显著降低,但在第6周后,与CS注射相比,PRP注射在降低疼痛评分方面更好(P=0.037)。最初,CS注射在第1周表现更好,这是由于抗炎作用。到第3周,两种注射都显示出相似的效果。然而,在研究期结束时(6周),PRP组的肩部疼痛和残疾指数(SPADI)疼痛评分(P=0.0057)和SPADI残疾评分(P=0.029)有更好的降低。结论:在治疗粘连性肩关节囊炎方面,USG引导下PRP水下剥离术在减轻疼痛和改善肩功能方面比CS更有效。
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引用次数: 0
Role of erector spinae plane block in end-of-life care for a patient with advanced abdominal malignancy 竖脊肌平面阻滞在晚期腹部恶性肿瘤患者临终关怀中的作用
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_19_22
Naina Kumar, Sunny Malik, Shraddha Malik, V. Sahni, S. Joshi
Celiac plexus block (CPB) is the most commonly used intervention in patients suffering from pain related to upper abdominal malignancies. Placing a CPB requires a patient to be placed in a prone position on the operating room table which becomes difficult in many patients with advanced disease and therefore makes it more challenging for the interventional pain physician, simultaneously risky for the patient. In such cases, a more superficial minimally invasive intervention is desirable. The erector spinae plane block (ESPB) is one such intervention that has been used in a large variety of settings and can be used in the abovementioned cases. So far, no reports have emphasized the role of this field block for chronic cancer pain relief in a patient with advanced and progressive malignancy nearing the end of life. We present such a case with end-stage carcinoma gallbladder, in which ESPB was used effectively for providing pain relief during her final days.
腹腔神经丛阻滞(CPB)是上腹部恶性肿瘤相关疼痛患者最常用的干预措施。放置CPB需要患者俯卧在手术室的手术台上,这对许多晚期疾病患者来说变得困难,因此对介入疼痛医生来说更具挑战性,同时对患者来说也有风险。在这种情况下,需要更肤浅的微创干预。竖脊肌平面阻滞(ESPB)是一种已经在各种环境中使用的干预措施,并且可以用于上述情况。到目前为止,还没有报告强调这种场阻滞在晚期和晚期恶性肿瘤患者中对慢性癌症疼痛缓解的作用。我们报告了这样一个终末期胆囊癌的病例,在她的最后几天,ESPB被有效地用于缓解疼痛。
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引用次数: 0
Ultrasound-guided multiple injection costotransverse block in a patient with postradiation therapy recurrent dermatofibrosarcoma protuberans: A technical glitch 超声引导下多次注射肋横阻滞治疗复发性隆突性皮肤纤维肉瘤1例:技术故障
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_107_21
D. Bhoi, Raunak Parida
Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive soft-tissue tumor with a high recurrence rate, often requiring multiple surgeries with multiple sessions of radiotherapy that alters the anatomy and makes regional anesthesia challenging in these patients. The multiple injection costotransverse block (MICB) is a type of “paravertebral by proxy” block in which the drug is injected within the thoracic intertransverse tissue complex with spread to the paravertebral space without any epidural spread. Unlike the traditional approach to paravertebral block, which involves piercing the superior costotransverse ligament, the MICB has a shallower needle trajectory making needle visualization easier and the more superficial needle tip location reduces the chances of a pleural puncture and subcostal vessel injury. We present the case of a 51-year-old male with recurrent DFSP in the anterior axillary fold who was posted for tumor debulking. As the sonoanatomy was altered due to multiple previous surgeries and radiotherapy, we chose to perform an ultrasound-guided MICB.
隆突性皮肤纤维肉瘤(DFSP)是一种局部侵袭性软组织肿瘤,复发率高,通常需要多次手术和多次放疗,这改变了解剖结构,使这些患者的区域麻醉变得困难。多重注射肋横阻滞(MICB)是一种“椎旁代用”阻滞,药物在胸椎横间组织复合体内注射,扩散到椎旁间隙,没有任何硬膜外扩散。与传统的椎旁阻滞入路(需刺穿上肋横韧带)不同,MICB的针迹较浅,更容易看到针,针尖位置较浅,减少了胸膜穿刺和肋下血管损伤的机会。我们提出的情况下,51岁的男性复发性DFSP在腋窝前襞谁张贴肿瘤去膨胀。由于先前多次手术和放疗导致超声解剖改变,我们选择进行超声引导下的MICB。
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引用次数: 0
Ideal pain-free hospital – A step forward 理想的无痛医院-向前迈进了一步
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_59_21
P. Jain, N. Dua, J. Sood, C. Sahai, Priya Yadav, Arti Sharma
Pain is the most common and distressing symptom which a patient fears when admitted to the hospital for medical or surgical reasons. Well-managed pain relief improves the quality of life, lessens complications, shortens hospital stay, and decreases health-care expenses. Inadequate control of pain has consequences that go beyond suffering: Insomnia, mood swings, decreased gut motility, reduced mobility, increased risk of deep-vein thrombosis, and respiratory and cardiac morbidity to name a few. The harsh reality is that postoperative pain is inadequately addressed worldwide, and many patients both inpatients and outpatients go home where they cannot manage their pain effectively. This is not necessarily the result of the absence of effective pain relief measures but is the outcome of inappropriate management for postoperative pain relief. The ideal pain-free hospital (PFH) is achievable by putting together a multidisciplinary team of pain physicians, pain nurses, physiotherapists, and other medical professionals. Education of the patient through counseling and printed handouts with information about postoperative pain and the techniques to manage it reduces anxiety. The PFH team is founded on the tenets of thorough preoperative assessment, better-educated pain-relieving staff along all the updated facilities. The pain education incorporates all teaching gadgets for medical and paramedical staff. Round-the-clock super-specialist pain relief services along with the preplanning of proper pain management, upgraded minimally invasive and daycare surgeries make the patient pain-free up to the maximum extent.
疼痛是患者因医疗或手术原因入院时最常见和最痛苦的症状。管理得当的止痛可以提高生活质量,减少并发症,缩短住院时间,并减少医疗费用。对疼痛控制不足的后果不仅限于痛苦:失眠、情绪波动、肠道运动能力下降、活动能力下降、深静脉血栓形成风险增加,以及呼吸和心脏疾病等。严酷的现实是,全世界都没有充分解决术后疼痛问题,许多住院患者和门诊患者回家后都无法有效控制疼痛。这不一定是缺乏有效止痛措施的结果,而是术后止痛管理不当的结果。理想的无痛医院(PFH)是通过组建一支由疼痛医生、疼痛护士、理疗师和其他医疗专业人员组成的多学科团队来实现的。通过咨询和印刷的关于术后疼痛的信息以及处理疼痛的技术来教育患者,可以减少焦虑。PFH团队建立在彻底的术前评估、受过更好教育的止痛人员以及所有更新设施的原则之上。疼痛教育包含了所有针对医护人员的教学设备。全天候的超级专业止痛服务,加上预先计划的适当疼痛管理、升级的微创和日托手术,使患者最大限度地减轻疼痛。
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引用次数: 0
Ultrasound guided rectus sheath and transverse abdominis blocks for robotic urological surgeries – A case series 超声引导直肌鞘和横腹阻滞用于机器人泌尿外科手术-一个病例系列
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_10_22
D. Rani, Shipra Aggarwal, Arushi Gupta, Pratibha Mudgal
Background: Robotic surgeries have improved perioperative outcomes. We have combined ultrasound (USG) guided bilateral rectus sheath (RS) block along with transverse abdominis plane (TAP) block to assess perioperative opioid requirement, visual analog scale (VAS) score, and modified Post Anesthetic Discharge Scoring System (PADSS) criteria for robotic urological surgeries. Ultrasound (USG)-guided blocks were given bilaterally after induction of general anesthesia. Methods: A total of ten patients scheduled for robotic urological surgeries were administered 30 ml of 0.25% bupivacaine (2.5 mg kg-1) with 0.75 mcg kg-1 of clonidine (10 ml of drug was given for TAP block and 5 ml of drug for RS block on each side) after negative aspiration. Results: Supplemental opioid was not required perioperatively, and 9 out of 10 patients were pain free (VAS score <3) for at least 6 h. Ten patients had a modified PADSS score ≥10 after 6 h of surgery. Conclusion: USG combined TAP and RS blocks is a promising technique with low learning curve, excellent analgesia, reduced opioid consumption, and higher PADSS score in the perioperative period.
背景:机器人手术改善了围手术期的预后。我们联合超声(USG)引导双侧直肌鞘(RS)阻滞和腹横平面(TAP)阻滞来评估机器人泌尿外科手术围手术期阿片类药物需求、视觉模拟量表(VAS)评分和改进的麻醉后出院评分系统(PADSS)标准。全麻诱导后双侧给予超声引导阻滞。方法:10例拟行泌尿外科机器人手术的患者,阴性抽吸后分别给予0.25%布比卡因(2.5 mg kg-1) 30 ml和可乐定(0.75 mcg kg-1),其中TAP阻断10 ml, RS阻断5 ml。结果:围手术期不需要补充阿片类药物,10例患者中有9例至少6小时无疼痛(VAS评分<3)。10例患者在手术6小时后改良PADSS评分≥10。结论:USG联合TAP和RS阻滞具有学习曲线低、镇痛效果好、阿片类药物消耗少、围手术期PADSS评分高的优点。
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引用次数: 0
Pulsed radiofrequency treatment of the dorsal root ganglion in patients with chronic neuropathic pain: A narrative review 脉冲射频治疗慢性神经性疼痛患者的背根神经节:叙述性综述
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_79_21
Sarah Waicus, Nishaant Bhambra
Background: Chronic neuropathic pain (CNP) is a complex condition that has profound impacts on quality of life. Pulsed radiofrequency (PRF) on the dorsal root ganglia (DRGs) is a novel treatment that has shown clinical efficacy in pain relief, however, its mechanism remains unknown. Objectives: The objective of this review is to synthesize the literature on inflammatory markers and clinical pain outcomes in CNP patients treated with PRF. Study Design: A narrative review was conducted. Setting: Eligibility criteria included human trials on adults diagnosed with CNP. Monopolar and bipolar PRF treatments on the DRG were included. Methods: Four peer reviewed electronic databases (Medline, EMBASE, PubMed, and Cochrane) were systematically searched for studies on PRF on the DRG to treat CNP. The primary outcome measures included pain scores and cerebrospinal fluid samples taken pre- and posttreatment measuring inflammatory markers. Results: Thirty-three articles were identified in the database searches. Titles, abstracts, and full-text articles were evaluated, and eight articles met the inclusion criteria. The study designs included five randomized-controlled trials and three quasi-experimental studies. Patients: There were 311 patients pooled with an age range of 35–76 years. Types of CNP included chronic radicular pain, postmastectomy pain syndrome, chronic lumbosacral pain, and postherpetic neuralgia. Intervention: Treatments in included studies included monopolar and bipolar PRF stimulation ranging from 120 s at 2 Hz to 360 s with 5 Hz pulses. Measurement: The main findings revealed that PRF treatment provided significant pain relief (P < 0.05), with the greatest pain reduction at 3 months. Pro-inflammatory markers were found to decrease, whereas anti-inflammatory markers increased post-PRF intervention. Limitations: There were differing PRF procedure standards, and it is uncertain whether a higher frequency or duration is correlated with better outcomes. Studies had small sample sizes increasing the margin of error. Longer duration randomized-controlled trials are needed to understand the optimal therapeutic duration using PRF.
背景:慢性神经性疼痛(CNP)是一种对生活质量有深远影响的复杂疾病。脉冲射频(PRF)治疗背根神经节(DRGs)是一种新的治疗方法,已显示出临床疗效,但其机制尚不清楚。目的:本综述的目的是综合有关PRF治疗CNP患者的炎症标志物和临床疼痛结局的文献。研究设计:采用叙述性回顾法。设定:入选标准包括诊断为CNP的成人人体试验。包括对DRG的单极和双极PRF治疗。方法:系统检索四个同行评审电子数据库(Medline, EMBASE, PubMed和Cochrane),检索PRF对DRG治疗CNP的研究。主要结局指标包括疼痛评分和治疗前后测量炎症标志物的脑脊液样本。结果:检索到33篇文献。对标题、摘要和全文文章进行了评估,有8篇文章符合纳入标准。研究设计包括5个随机对照试验和3个准实验研究。患者:311例患者,年龄35 ~ 76岁。CNP的类型包括慢性神经根痛、乳房切除术后疼痛综合征、慢性腰骶痛和带状疱疹后神经痛。干预:纳入研究的治疗包括单极和双极PRF刺激,刺激时间从120秒2hz到360秒5hz脉冲。测量:主要研究结果显示,PRF治疗可显著缓解疼痛(P < 0.05), 3个月时疼痛减轻最大。prf干预后,促炎标志物减少,而抗炎标志物增加。局限性:有不同的PRF程序标准,并且不确定更高的频率或持续时间是否与更好的结果相关。研究样本量小,增加了误差范围。需要更长时间的随机对照试验来了解使用PRF的最佳治疗时间。
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引用次数: 0
Radiofrequency to the rescue in a case of pancoast tumor 射频治疗胰腺癌1例
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_74_22
Prateek Arora, Abhishek Bharadwaj
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引用次数: 0
A prospective study to determine the effect of Vitamin D levels on musculoskeletal pain, anxiety, and depressions in patients with type II diabetes 一项确定维生素D水平对2型糖尿病患者肌肉骨骼疼痛、焦虑和抑郁影响的前瞻性研究
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_1_22
Raunak Kumar, N. Laisram, N. Jain
Objectives: The primary objective was to investigate the correlation of musculoskeletal pain (MSP) intensity with Vitamin D status and glycemic control in patients of type II diabetes mellitus. The secondary objective was to monitor the anxiety and depression levels with Vitamin D supplementation. Methods: A prospective observational cohort study was conducted over a period of 18 months where 100 patients of type II diabetes mellitus with MSP were screened for Vitamin D status and glycemic levels in terms of HbA1c, anxiety, and depression. MSP was assessed by Visual Analog Scale (VAS) score. The patients who were found with Vitamin D levels (<30 ug/dL) were supplemented with Vitamin D and followed at 3 monthly intervals for 6 months for determining the change in MSP, anxiety, and depression scores. Results: After adjusting for the duration of diabetes, HbA1c, and statin therapy, there was no significant correlation between VAS score and Vitamin D (r = −0.133, P = 0.195). After 6 months of Vitamin D supplementation, all cases attained optimal Vitamin D levels of mean (standard deviation [SD]) of 32.5 (4.1) ng/ml as compared to mean (SD) of 23.4 (2.5) ng/ml at baseline (P < 0.0001). Concurrently, there was a significant reduction in the median (range) VAS scores from 6 (2–10) to 4 (0–8), anxiety levels from 11 (7.75–18) to 10 (7–17), and depression levels from 10 (7–15) to 9 (6–14) (P < 0.0001), respectively. Conclusion: There was no significant independent correlation of MSP intensity with Vitamin D levels or glycemic control. However, the supplementation of Vitamin D significantly alleviated MSP in patients with diabetes, with a significant reduction in anxiety and depression among them.
目的:主要目的是研究II型糖尿病患者的肌肉骨骼疼痛(MSP)强度与维生素D水平和血糖控制的相关性。第二个目标是通过补充维生素D来监测焦虑和抑郁水平。方法:一项为期18个月的前瞻性观察队列研究,对100例伴有MSP的2型糖尿病患者进行了维生素D状态和血糖水平的筛查,包括HbA1c、焦虑和抑郁。采用视觉模拟量表(VAS)评定MSP。发现维生素D水平(<30 ug/dL)的患者补充维生素D,并每隔3个月随访6个月,以确定MSP,焦虑和抑郁评分的变化。结果:在调整糖尿病、HbA1c和他汀类药物治疗的持续时间后,VAS评分与维生素D无显著相关性(r = - 0.133, P = 0.195)。补充维生素D 6个月后,所有病例的维生素D平均(标准差[SD])均达到最佳水平,为32.5 (4.1)ng/ml,而基线时的平均值(SD)为23.4 (2.5)ng/ml (P < 0.0001)。同时,VAS评分中位数(范围)从6(2-10)降至4(0-8),焦虑水平从11(7.75-18)降至10(7-17),抑郁水平从10(7-15)降至9 (6 - 14)(P < 0.0001)。结论:MSP强度与维生素D水平或血糖控制无显著的独立相关性。然而,补充维生素D可以显著缓解糖尿病患者的MSP,显著减少其中的焦虑和抑郁。
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引用次数: 0
A technical report of postmastectomy axillary web syndrome symptom management using ultrasound-guided trigger point injections 超声引导触发点注射治疗乳房切除术后腋窝蹼综合征的技术报告
Pub Date : 2022-05-01 DOI: 10.4103/ijpn.ijpn_105_21
Mohammad H. Bawany, R. Subramony, J. Castellanos, J. Oswald
Axillary web syndrome (AWS) is a painful and difficult-to-manage complication of breast surgery with axillary lymph node dissection. Patients may believe that symptoms, including the presence of palpable axillary cords and reduced shoulder mobility, are a normal part of postoperative recovery. Both physician and patient education regarding this quality-of-life impairing condition is needed. In this report, we describe treating AWS using ultrasound-guided trigger point injections to avoid inadvertent damage to the neighboring lung, nerve, lymph nodes, and/or vasculature. There is limited information on their utility in treating AWS. At 4-month follow-up, our patient reported 70% improvement in her pain and discontinuation of her opioid medications, along with increased functionality. Ultrasound played a critical role in enhancing procedure accuracy and safety in zones that contain important nerve and vascular tissue and decreasing the risk of iatrogenic injury. While ultrasound was used historically for diagnostic purposes, we show why its use for interventions is on the rise.
腋网综合征(AWS)是乳腺外科腋窝淋巴结清扫术中一种痛苦且难以控制的并发症。患者可能认为,包括可触摸的腋窝索和肩部活动能力下降在内的症状是术后恢复的正常部分。医生和患者都需要对这种损害生活质量的情况进行教育。在本报告中,我们描述了使用超声波引导的触发点注射治疗AWS,以避免对邻近的肺、神经、淋巴结和/或血管系统的无意损伤。关于它们在治疗AWS方面的效用,信息有限。在4个月的随访中,我们的患者报告她的疼痛改善了70%,停止了阿片类药物治疗,同时功能增强。超声在提高包含重要神经和血管组织的区域的手术准确性和安全性以及降低医源性损伤的风险方面发挥了关键作用。虽然超声波在历史上被用于诊断目的,但我们展示了为什么它在干预中的用途正在增加。
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引用次数: 0
期刊
Indian Journal of Pain
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