Objectives: This study designed to assess the genomic instability between healthy women and women with breast cancer by means of buccal cells micronucleus (MN) cytome assay. Methods: The current study comprised 25 healthy women and 30 breast cancer patients. The exfoliated cells of buccal mucosa were taken after each participants rinse their mouths with tap water. The micronucleated cell and nuclear anomalies were analyzed under a total magnification of X1000, 2000 cells per subjects ( patient and control group) were scored and the frequencies of nuclear anomalies including MN, binucleates (BN), Pycnotic cell, karyolysis (KL) and karyorrhexis (KR) were evaluated in exfoliated buccal mucosa cells of women with primary BC and healthy women. Results: The frequencies of micronuclei and all nuclear anomalies in buccal cells of BC patients were significantly increased compared with the controls. (For Binucleates cells only, p<0.001; in all other cases, P < 0.0001). The mean scores of micronuclei and all nuclear anomalies for the breast cancer patients were (10.66±0.3845, 6.20±0.26, 8.40±0. 22, 18.40±0. 34, 19.13 ±0.40) were significantly higher than that of healthy women). Conclusion: Elevated frequency of micronucleated cells and all nuclear anomalies in the buccal mucosa of breast cancer patients reveal the genomic instability. These findings propose that the buccal MN-cytome assay can be used to measure both genotoxic and cytotoxic effects in primary cancer patients.
{"title":"Micronuclei and Other Nuclear Anomalies in Exfoliated Buccal Mucosa Cells in Breast Cancer","authors":"","doi":"10.22317/imj.v5i3.1043","DOIUrl":"https://doi.org/10.22317/imj.v5i3.1043","url":null,"abstract":"Objectives: This study designed to assess the genomic instability between healthy women and women with breast cancer by means of buccal cells micronucleus (MN) cytome assay. Methods: The current study comprised 25 healthy women and 30 breast cancer patients. The exfoliated cells of buccal mucosa were taken after each participants rinse their mouths with tap water. The micronucleated cell and nuclear anomalies were analyzed under a total magnification of X1000, 2000 cells per subjects ( patient and control group) were scored and the frequencies of nuclear anomalies including MN, binucleates (BN), Pycnotic cell, karyolysis (KL) and karyorrhexis (KR) were evaluated in exfoliated buccal mucosa cells of women with primary BC and healthy women. Results: The frequencies of micronuclei and all nuclear anomalies in buccal cells of BC patients were significantly increased compared with the controls. (For Binucleates cells only, p<0.001; in all other cases, P < 0.0001). The mean scores of micronuclei and all nuclear anomalies for the breast cancer patients were (10.66±0.3845, 6.20±0.26, 8.40±0. 22, 18.40±0. 34, 19.13 ±0.40) were significantly higher than that of healthy women). Conclusion: Elevated frequency of micronucleated cells and all nuclear anomalies in the buccal mucosa of breast cancer patients reveal the genomic instability. These findings propose that the buccal MN-cytome assay can be used to measure both genotoxic and cytotoxic effects in primary cancer patients.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89980580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aimed to evaluate the activity of several remarkable enzymes in the serum of breast cancer and estimate their potential value in the diagnosis of breast cancer.Methods: The study comprised of 70 patients with breast cancer and 50 age and sex-matched healthy subjects as controls. Levels of (5 –Nucleotidase), Acid phosphatase activity (ACP), Glutamate dehydrogenase (GDH), Serum β-glucuronidase, Aldehyde dehydrogenase (ALDH), Alcohol Dehydrogenase (ADH), Superoxide dismutase (SOD) and Adenosine deaminase ADA were measured using enzymatic methods.Results: There was a significant increase in the Catalytic activities of 5 –Nucleotidase((p<0.001), ACP ( p< 0.05), GDH ( ≤0.001 p), Serum β-glucuronidase (p<0.0001), ADH ( p< 0.001), SOD (p< 0.001))and ADA(p< 0.001),while there was no significant increase in the level of Aldehyde dehydrogenase (ALDH)( p = 0.231)in sera of breast cancer patients compared to the control.Conclusion: The present study strongly indicates the potential role of SOD, GDH, ADH, GDH,5–Nucleotidase,GLU and ACP as important biomarkers in breast cancer.
{"title":"Diagnosis of Breast Cancer by some remarkable enzymes","authors":"P. Ismail, A. Yousif","doi":"10.22317/IMJ.V5I3.1056","DOIUrl":"https://doi.org/10.22317/IMJ.V5I3.1056","url":null,"abstract":"Objectives: This study aimed to evaluate the activity of several remarkable enzymes in the serum of breast cancer and estimate their potential value in the diagnosis of breast cancer.Methods: The study comprised of 70 patients with breast cancer and 50 age and sex-matched healthy subjects as controls. Levels of (5 –Nucleotidase), Acid phosphatase activity (ACP), Glutamate dehydrogenase (GDH), Serum β-glucuronidase, Aldehyde dehydrogenase (ALDH), Alcohol Dehydrogenase (ADH), Superoxide dismutase (SOD) and Adenosine deaminase ADA were measured using enzymatic methods.Results: There was a significant increase in the Catalytic activities of 5 –Nucleotidase((p<0.001), ACP ( p< 0.05), GDH ( ≤0.001 p), Serum β-glucuronidase (p<0.0001), ADH ( p< 0.001), SOD (p< 0.001))and ADA(p< 0.001),while there was no significant increase in the level of Aldehyde dehydrogenase (ALDH)( p = 0.231)in sera of breast cancer patients compared to the control.Conclusion: The present study strongly indicates the potential role of SOD, GDH, ADH, GDH,5–Nucleotidase,GLU and ACP as important biomarkers in breast cancer.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76786309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aimed to show the Epidemiology of Asymptomatic Bacteriuria among diabetic patients in Tikrit City, Iraq. Methods: A cross sectional study was conducted in Tikrit city among diabetic and non-diabetic patients from General Salahalddin Hospital and from outpatient clinics. This study conduct 270 persons, including 155 diabetes sufferers and 115 non-diabetics. Consented subjects had their mid-stream urine collected, and each sample was examined using microscopy and culture techniques. Standard microbiological assays to determine the presence of pus cells and bacteria in urine were used to identify isolates. Results: Asymptomatic Bacteriuria (ASB) was found in 21.5 % of subjects, with diabetics having 26.4 % and non-diabetics having 14.8 %. ASB is higher in the age group above 51 years 29 (50%), Females 51 (88%) demonstrated a higher prevalence than males 7(12%) in both diabetic and non-diabetic groups. Staphylococcus epidermidis was the most common bacterium isolated from urine in both diabetics and non-diabetics (22.4 %). Other bacterium isolates included E. coli (19%) , Enterococcus fecalis (13.7%), Klebsiella pneumonia (12%), and Enterobacter sp (12%), Staph aureus (10.3%), Staph saprophyticus (6.8%), Pseudomonas aerogenosa (3.4%). The most of isolated microorganisms were resistance to gentamycin, trimethoprim and cefotrixone. Levofloxacin and ciprofloxacin were the most sensitive to uropathogens caused by bacteria . Conclusion: Diabetic sufferers had a higher prevalence of ASB (26.4%) than non-diabetics, according to the study (14.8 %). The majority of ASB was caused by Staphylococcus sp, indicating a shift in the aetiologic spectrum. The majority of isolates demonstrated multiple resistance in both diabetics and non-diabetics, indicating the necessity to increase antibiotic sensitization in Tikrit.
{"title":"Epidemiology of Asymptomatic Bacteriuria among diabetic patients in Tikrit City, Iraq","authors":"","doi":"10.22317/imj.v5i3.1041","DOIUrl":"https://doi.org/10.22317/imj.v5i3.1041","url":null,"abstract":"Objectives: This study aimed to show the Epidemiology of Asymptomatic Bacteriuria among diabetic patients in Tikrit City, Iraq. Methods: A cross sectional study was conducted in Tikrit city among diabetic and non-diabetic patients from General Salahalddin Hospital and from outpatient clinics. This study conduct 270 persons, including 155 diabetes sufferers and 115 non-diabetics. Consented subjects had their mid-stream urine collected, and each sample was examined using microscopy and culture techniques. Standard microbiological assays to determine the presence of pus cells and bacteria in urine were used to identify isolates. Results: Asymptomatic Bacteriuria (ASB) was found in 21.5 % of subjects, with diabetics having 26.4 % and non-diabetics having 14.8 %. ASB is higher in the age group above 51 years 29 (50%), Females 51 (88%) demonstrated a higher prevalence than males 7(12%) in both diabetic and non-diabetic groups. Staphylococcus epidermidis was the most common bacterium isolated from urine in both diabetics and non-diabetics (22.4 %). Other bacterium isolates included E. coli (19%) , Enterococcus fecalis (13.7%), Klebsiella pneumonia (12%), and Enterobacter sp (12%), Staph aureus (10.3%), Staph saprophyticus (6.8%), Pseudomonas aerogenosa (3.4%). The most of isolated microorganisms were resistance to gentamycin, trimethoprim and cefotrixone. Levofloxacin and ciprofloxacin were the most sensitive to uropathogens caused by bacteria . Conclusion: Diabetic sufferers had a higher prevalence of ASB (26.4%) than non-diabetics, according to the study (14.8 %). The majority of ASB was caused by Staphylococcus sp, indicating a shift in the aetiologic spectrum. The majority of isolates demonstrated multiple resistance in both diabetics and non-diabetics, indicating the necessity to increase antibiotic sensitization in Tikrit.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79399287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhanad Hadi Abbood, J. Hassan, Aqeel Jassim Mehammed
Objectives: The aim of study is to study Case study of COVID 19 in Babylon Province in Iraq. Method: In January 2021 we started searching for the official source for the numbers of people infected with COVID19 within the borders of Babylon Governorate, where the Babylon Health Department was reviewed, and after that we were directed with official authorization to the Public Health Department in Babylon Governorate / Department of Communicable Diseases / Respiratory Diseases Unit (weekly periodic visit). Where the official numbers were obtained for the number of infected people and the number of deaths that occur due to complication with this infection, as well as the number of recovery cases from the date of 01/08/2020 to 01/01/2021. Results: related to the number of infected cases we see decrease the no. of infected with corona virus in Babylon Governorate from beginning the study to become lest at the end of 2020 with the significant decrease (P < 0.05) (The highest infected cases were notices in first month (1/8 – 31/8) while the lowest cases were seen in last month (1/12 – 31/12)) that may be due to: The main cause may be the most people may have gained herd immunity or population immunity, is the indirect protection from an infectious disease that happens when a population is have immunity developed through previous infection, that may refer to the end of first wave of this pandemic which start from the June. Conclusion: Knowing the pathogenesis of the virus and risk factors, increasing the experience of doctors and working cadres, increasing clinical capacity, providing specialized treatments, increasing the number of ICU beds, in addition to increasing the number of respiratory ventilators and increasing the number of tests.
{"title":"Case study of COVID 19 from August to end of December 2020 in Babylon, Iraq","authors":"Muhanad Hadi Abbood, J. Hassan, Aqeel Jassim Mehammed","doi":"10.22317/imj.v5i3.1078","DOIUrl":"https://doi.org/10.22317/imj.v5i3.1078","url":null,"abstract":"Objectives: The aim of study is to study Case study of COVID 19 in Babylon Province in Iraq. Method: In January 2021 we started searching for the official source for the numbers of people infected with COVID19 within the borders of Babylon Governorate, where the Babylon Health Department was reviewed, and after that we were directed with official authorization to the Public Health Department in Babylon Governorate / Department of Communicable Diseases / Respiratory Diseases Unit (weekly periodic visit). Where the official numbers were obtained for the number of infected people and the number of deaths that occur due to complication with this infection, as well as the number of recovery cases from the date of 01/08/2020 to 01/01/2021. Results: related to the number of infected cases we see decrease the no. of infected with corona virus in Babylon Governorate from beginning the study to become lest at the end of 2020 with the significant decrease (P < 0.05) (The highest infected cases were notices in first month (1/8 – 31/8) while the lowest cases were seen in last month (1/12 – 31/12)) that may be due to: The main cause may be the most people may have gained herd immunity or population immunity, is the indirect protection from an infectious disease that happens when a population is have immunity developed through previous infection, that may refer to the end of first wave of this pandemic which start from the June. Conclusion: Knowing the pathogenesis of the virus and risk factors, increasing the experience of doctors and working cadres, increasing clinical capacity, providing specialized treatments, increasing the number of ICU beds, in addition to increasing the number of respiratory ventilators and increasing the number of tests.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81463814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: In December 2019, SARS-CoV2 outbreak from China resulted in Covid-19 worldwide. The involvement of different organs, especially, heart disease can lead to hospitalization and enhance the rate of mortality and morbidity among severe patients. In a narrative review, we aimed to investigate the involvement of heart in adult and children with COVID-19 in critically ill patients. Methods: The clinical and paraclinical manifestation of diseases in adults and children were searched in standard databases, such as PubMed, Google Scholar, Scopus, est. Also, the possible underlying mechanisms were investigated. Results: The CVDs in COVID-19 patients has been characterized by several abnormalities such as myocarditis, acute myocardial injury, acute coronary syndrome, heart failure, arrhythmias, sudden cardiac arrest, coagulation abnormalities, thrombosis, and Kawasaki disease. The most probable mechanisms are attributed to SARS-CoV2 direct and indirect effects. The presence of angiotensin-converting enzyme 2 (ACE2) was confirmed in the cardiac tissue, confirming the direct attack of virus. Moreover, the cytokine storm as a result of enhanced levels of inflammatory mediators and infiltration of inflammatory cells into the cardiac disease, coagulation abnormalities, and endothelial dysfunction contribute to disease. Conclusion: Cardiac diseases are seen in children and adults with COVID-19, related to the different mechanisms, mainly direct attack of virus and cytokine storm. Increasing the knowledge of cardiologists about the cardiac manifestations of COVID-9 in children and adults and underlying mechanisms can improve the consequences and reduce the mortality and morbidity rate among hospitalized patients.
{"title":"Cardiac diseases following COVID-19 in children and adults: A narrative review on mechanisms and medical implications","authors":"","doi":"10.22317/imj.v5i3.1044","DOIUrl":"https://doi.org/10.22317/imj.v5i3.1044","url":null,"abstract":"Objectives: In December 2019, SARS-CoV2 outbreak from China resulted in Covid-19 worldwide. The involvement of different organs, especially, heart disease can lead to hospitalization and enhance the rate of mortality and morbidity among severe patients. In a narrative review, we aimed to investigate the involvement of heart in adult and children with COVID-19 in critically ill patients. Methods: The clinical and paraclinical manifestation of diseases in adults and children were searched in standard databases, such as PubMed, Google Scholar, Scopus, est. Also, the possible underlying mechanisms were investigated. Results: The CVDs in COVID-19 patients has been characterized by several abnormalities such as myocarditis, acute myocardial injury, acute coronary syndrome, heart failure, arrhythmias, sudden cardiac arrest, coagulation abnormalities, thrombosis, and Kawasaki disease. The most probable mechanisms are attributed to SARS-CoV2 direct and indirect effects. The presence of angiotensin-converting enzyme 2 (ACE2) was confirmed in the cardiac tissue, confirming the direct attack of virus. Moreover, the cytokine storm as a result of enhanced levels of inflammatory mediators and infiltration of inflammatory cells into the cardiac disease, coagulation abnormalities, and endothelial dysfunction contribute to disease. Conclusion: Cardiac diseases are seen in children and adults with COVID-19, related to the different mechanisms, mainly direct attack of virus and cytokine storm. Increasing the knowledge of cardiologists about the cardiac manifestations of COVID-9 in children and adults and underlying mechanisms can improve the consequences and reduce the mortality and morbidity rate among hospitalized patients.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75361822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aimed to evaluate the role of Pap test in detecting pre-cancerous lesions in Iraqi women aged 45 years to 85 years, correlate the pap result with patient’s age, parity, number of births, number of abortions, chief complaint, and clinical cervical exam, and to evaluate the diagnostic accuracy of the pap test in correlation to histopathological examination. Methods: Women who attended the outpatient gynaecological clinic of the Department of Obstetrics and Gynaecology at Baghdad medical city, Baghdad, Iraq, from January 2019 to January 2020 who had different chief complaints were selected for the study. Women who are 45 years to 85 years old were included in the study. A Pap smear was used for all women to screen for cervical cancer and the results were reported according to the 2014 Bethesda system. The data analysis was done utilizing statistical package for social sciences version 24 (SPSS v24). Results: Total number of pap smears analyzed were 510, NILM (negative for intraepithelial lesions or malignancy) constituted major group 464/510 (91%) and epithelial cell abnormality were 46/510 (9%), age is significantly correlated with increasing rate of pre-neoplastic and neoplastic lesions in women and the significance of vaginal discharge & postmenopausal bleeding and its association with premalignant changes in the cervix. The sensitivity of Pap test is 94%, the Specificity was 60% and accuracy rate 74%. Conclusion: There is significant correlation between Pap smear abnormality and increasing age, vaginal discharge and postmenopausal bleeding, were evident in this study.
{"title":"The Cervical pap smear cytological changes with clinicopathological correlation in a sample of Iraqi patients","authors":"","doi":"10.22317/imj.v5i3.1018","DOIUrl":"https://doi.org/10.22317/imj.v5i3.1018","url":null,"abstract":"Objectives: This study aimed to evaluate the role of Pap test in detecting pre-cancerous lesions in Iraqi women aged 45 years to 85 years, correlate the pap result with patient’s age, parity, number of births, number of abortions, chief complaint, and clinical cervical exam, and to evaluate the diagnostic accuracy of the pap test in correlation to histopathological examination. Methods: Women who attended the outpatient gynaecological clinic of the Department of Obstetrics and Gynaecology at Baghdad medical city, Baghdad, Iraq, from January 2019 to January 2020 who had different chief complaints were selected for the study. Women who are 45 years to 85 years old were included in the study. A Pap smear was used for all women to screen for cervical cancer and the results were reported according to the 2014 Bethesda system. The data analysis was done utilizing statistical package for social sciences version 24 (SPSS v24). Results: Total number of pap smears analyzed were 510, NILM (negative for intraepithelial lesions or malignancy) constituted major group 464/510 (91%) and epithelial cell abnormality were 46/510 (9%), age is significantly correlated with increasing rate of pre-neoplastic and neoplastic lesions in women and the significance of vaginal discharge & postmenopausal bleeding and its association with premalignant changes in the cervix. The sensitivity of Pap test is 94%, the Specificity was 60% and accuracy rate 74%. Conclusion: There is significant correlation between Pap smear abnormality and increasing age, vaginal discharge and postmenopausal bleeding, were evident in this study.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81386446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aimed to investigate determination of hyponatremia prevalence in admitted patients in Oncology teaching hospital. Methods: 6 months cross sectional study of hyponatremia prevalence done in Oncology ward in Medical city, patients (105) who were admitted for more than three days with different types of malignancies, and causes of admission, were investigated for serum sodium, Blood urea, random blood sugar, urinary Na. (single measurement) and compared to S.Na level of control (135) of non-caner individuals with same exclusion criteria. Results: The prevalence of hyponatremia in admitted patient was 43.7%, compared to 0.73% in control group. Conclusion: the prevalence of hyponatremia in Oncology teaching hospital / Medical city ward was higher than previous studies (done in international cancer centres), hyposmolarhyponatremia prevalence is almost similar to previous studies.
{"title":"Prevalence of Hyponatremia in admitted patients in Oncology teaching hospital","authors":"","doi":"10.22317/imj.v5i2.991","DOIUrl":"https://doi.org/10.22317/imj.v5i2.991","url":null,"abstract":"Objectives: This study aimed to investigate determination of hyponatremia prevalence in admitted patients in Oncology teaching hospital. Methods: 6 months cross sectional study of hyponatremia prevalence done in Oncology ward in Medical city, patients (105) who were admitted for more than three days with different types of malignancies, and causes of admission, were investigated for serum sodium, Blood urea, random blood sugar, urinary Na. (single measurement) and compared to S.Na level of control (135) of non-caner individuals with same exclusion criteria. Results: The prevalence of hyponatremia in admitted patient was 43.7%, compared to 0.73% in control group. Conclusion: the prevalence of hyponatremia in Oncology teaching hospital / Medical city ward was higher than previous studies (done in international cancer centres), hyposmolarhyponatremia prevalence is almost similar to previous studies.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80762039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: In this study, we have evaluated the effects of isolated arthroscopic lateral retinacular release in lateral patellar compression syndrome according to Lysholm Knee Scoring Scale. Methods: a prospective case series study of 48 patients who suffered Lateral patellar compression syndrome who were diagnosed by clinical examination and confirmed by M.R.I. and failed conservative management and underwent isolated arthroscopic lateral patellar retinaculum. Results: There was significant improvement in Lysholm score, in particular for pain, using stairs and squatting. The procedure had a high mean satisfaction score of 83.15 post operatively which is significant compared to preoperative score which was 51.17 (p<0.001). Conclusion: Isolated patella retinaculum release can be effective for relieving anterior knee pain in isolated lateral patellar compression syndrome without significant instability or mal-alignment.
{"title":"Clinical Outcome of Arthroscopic Lateral Release for Lateral Patellar Compression Syndrome","authors":"","doi":"10.22317/imj.v5i2.1010","DOIUrl":"https://doi.org/10.22317/imj.v5i2.1010","url":null,"abstract":"Objective: In this study, we have evaluated the effects of isolated arthroscopic lateral retinacular release in lateral patellar compression syndrome according to Lysholm Knee Scoring Scale. Methods: a prospective case series study of 48 patients who suffered Lateral patellar compression syndrome who were diagnosed by clinical examination and confirmed by M.R.I. and failed conservative management and underwent isolated arthroscopic lateral patellar retinaculum. Results: There was significant improvement in Lysholm score, in particular for pain, using stairs and squatting. The procedure had a high mean satisfaction score of 83.15 post operatively which is significant compared to preoperative score which was 51.17 (p<0.001). Conclusion: Isolated patella retinaculum release can be effective for relieving anterior knee pain in isolated lateral patellar compression syndrome without significant instability or mal-alignment.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87761902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: to find out the long-term results of tracheal reconstruction in terms of presentation, operation, complications, and outcomes of tracheal reconstruction. Methods: In this case-series study, the patients who developed post-intubation tracheal stenosis following respiratory failure were followed up for two years for the possible complications. The patients were diagnosed by experienced pulmonologist in two surgical centers, Erbil and Sulaimaniya in Iraqi Kurdistan in 2017. Results: The number of patients who were included in this study was 20; including males (n=13) and females (n=7) ranged between 18-58 years. The causes of the stenosis in patients were post-intubation (n=18) and post-tracheostomy for trauma (n=5). Most patients underwent extubation after 72 hours. The Myer-Cotton Grade of stenosis were grade 1 (n=1), grade 2 (n=13), and grade 3 (n=6). The major complications were dehiscence (n=3) and anastomotic edema (n=5). The minor complications were granulation (n=13) and mild anastomotic edema (n=1). One patient developed a surgical site infection and one patient developed a mild infection. The anastomotic fibrin deposition was developed in five patients. All patients had excellent satisfaction except for two patients (unsatisfactory). One of these patients died at month 1. The patients had normal medical conditions at different times of follow-ups. Conclusions: This study showed that the results of the patients with post-traumatic tracheal stenosis were acceptable at different times for most of them.
{"title":"Post-Traumatic Tracheal Stenosis: Results of Tracheal Reconstruction: A Multicenter Case Series","authors":"A. Rasool, Bashar Hanna Azar, A. Baram","doi":"10.22317/imj.v5i2.1028","DOIUrl":"https://doi.org/10.22317/imj.v5i2.1028","url":null,"abstract":"Objectives: to find out the long-term results of tracheal reconstruction in terms of presentation, operation, complications, and outcomes of tracheal reconstruction. Methods: In this case-series study, the patients who developed post-intubation tracheal stenosis following respiratory failure were followed up for two years for the possible complications. The patients were diagnosed by experienced pulmonologist in two surgical centers, Erbil and Sulaimaniya in Iraqi Kurdistan in 2017. Results: The number of patients who were included in this study was 20; including males (n=13) and females (n=7) ranged between 18-58 years. The causes of the stenosis in patients were post-intubation (n=18) and post-tracheostomy for trauma (n=5). Most patients underwent extubation after 72 hours. The Myer-Cotton Grade of stenosis were grade 1 (n=1), grade 2 (n=13), and grade 3 (n=6). The major complications were dehiscence (n=3) and anastomotic edema (n=5). The minor complications were granulation (n=13) and mild anastomotic edema (n=1). One patient developed a surgical site infection and one patient developed a mild infection. The anastomotic fibrin deposition was developed in five patients. All patients had excellent satisfaction except for two patients (unsatisfactory). One of these patients died at month 1. The patients had normal medical conditions at different times of follow-ups. Conclusions: This study showed that the results of the patients with post-traumatic tracheal stenosis were acceptable at different times for most of them.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77932472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To evaluate renal function change after percutaneous nephrolithotomy in patients with solitary kidney. Methods: A prospective study conducted in the urology department at Rizgary Teaching Hospital for a period of 15 months from first of June 2018 until the end of August 2019. It included nine adult patients, all of them with solitary kidney and undergone percutaneous nephrolithotomy for management of renal calculi. Patients were considered to have a solitary kidney in case of congenital abnormality, contralateral nephrectomy, or solitary functioning kidney with contralateral atrophy (relative function < 10%). All patients were received prophylactic antibiotics (Ceftriaxone) at induction of anesthesia. All percutaneous nephrolithotomy procedures performed under general anesthesia in the prone position. Serum creatinine and creatinine clearance before the operation, at day one and day 21 postoperatively, operation time, duration of hospitalization, and postoperative complications recorded. Results: In this study, Means of serum creatinine at 1 day and 21 days postoperatively were significantly decreased compared to preoperative s. creatinine level Mean of creatinine clearance significantly increased after 21 days postoperatively compared to preoperative test, while no significant change in creatinine clearance after one day postoperatively. Conclusion: Generally, percutaneous nephrolithotomy considered as a safe and effective option for treatment of renal stones in solitary kidney patients considering the overall rate of complications and minimal morbidity. Moreover, significant renal function improvement anticipated in the early postoperative period.
{"title":"Renal function evaluation after percutaneous nephrolithotomy in patients with solitary kidney","authors":"","doi":"10.22317/imj.v5i2.1027","DOIUrl":"https://doi.org/10.22317/imj.v5i2.1027","url":null,"abstract":"Objective: To evaluate renal function change after percutaneous nephrolithotomy in patients with solitary kidney. Methods: A prospective study conducted in the urology department at Rizgary Teaching Hospital for a period of 15 months from first of June 2018 until the end of August 2019. It included nine adult patients, all of them with solitary kidney and undergone percutaneous nephrolithotomy for management of renal calculi. Patients were considered to have a solitary kidney in case of congenital abnormality, contralateral nephrectomy, or solitary functioning kidney with contralateral atrophy (relative function < 10%). All patients were received prophylactic antibiotics (Ceftriaxone) at induction of anesthesia. All percutaneous nephrolithotomy procedures performed under general anesthesia in the prone position. Serum creatinine and creatinine clearance before the operation, at day one and day 21 postoperatively, operation time, duration of hospitalization, and postoperative complications recorded. Results: In this study, Means of serum creatinine at 1 day and 21 days postoperatively were significantly decreased compared to preoperative s. creatinine level Mean of creatinine clearance significantly increased after 21 days postoperatively compared to preoperative test, while no significant change in creatinine clearance after one day postoperatively. Conclusion: Generally, percutaneous nephrolithotomy considered as a safe and effective option for treatment of renal stones in solitary kidney patients considering the overall rate of complications and minimal morbidity. Moreover, significant renal function improvement anticipated in the early postoperative period.","PeriodicalId":32555,"journal":{"name":"Iraq Medical Journal","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76000932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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