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Review of Feto-Maternal Outcome in Patients with Premature Rupture of Membranes at Term 临产时胎膜早破患者的胎儿-产妇结局回顾
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.855
Sadia Ali Khan, Fatima Imran, Junaid Ali Khan
Background: Premature rupture of membranes complicates 5 to 10 % of the singleton pregnancies and is a major contributor of maternal morbidity and neonatal morbidity and mortality in terms of sepsis and prematurity, even in the today's era of antibiotics. Most of these complications can be prevented provided timely, targeted management is initiated.Objectives: To provide a comprehensive understanding of the fetal and maternal outcome with premature rupture of membranes at term, for a better management.Material and Methods: This descriptive Cross Sectional study was conducted in department of Obstetrics and Gynecology HMC, from 15th of September 2022 till 15th of February 2023. Random sampling method was adopted in this study and a total of 241 patients presented with spontaneous rupture of membranes after 37 weeks till 41 weeks. A detail history, physical and gynecological examination was performed, and all the information gathered from the patient by the doctors was then recorded on a pre-designed proforma.Results: Out of 241 patients of PROM 60 cases of maternal and 145 cases of fetal complications were observed. As per maternal outcomes, 28(46.7%) patients had wound infection,16(26.6%) patients developed oligohydramnios, 07 (11.7%) patients were recorded with Puerperal Pyrexia secondary to endometritis, and 09 (15%) patients developed chorio-amnionitis. About 56% of the mothers had cesearen deliveries. As per fetal outcomes, 78(53.8%) cases were recorded with RDS, 35(24.1) with hyperbilirubinemia, 23 (16%) babies developed neonatal sepsis, and 09(6.2%) had necrotizing Enterocolitis. Conclusion: Premature Rupture of Membrane at term has a risk of both fetal and maternal complications. Prolonging pregnancy as in conservative management adds to the fetal and maternal morbidity more in terms of sepsis. In this study, we concluded that conservative management to prolong pregnancy carry risk both for mother and baby and is recommended only under strict monitoring.Keywords: Chorioamnionitis, Latency period, Maternal outcome, Perinatal outcome, Sepsis.
背景:胎膜早破是 5%至 10%的单胎妊娠的并发症,即使在当今使用抗生素的时代,胎膜早破也是导致产妇发病、新生儿发病和死亡的主要原因,包括败血症和早产。只要及时采取有针对性的治疗措施,大多数并发症都是可以预防的:全面了解足月胎膜早破对胎儿和产妇的影响,以便更好地进行处理:这项描述性横断面研究于 2022 年 9 月 15 日至 2023 年 2 月 15 日在 HMC 妇产科进行。本研究采用随机抽样法,共有 241 名患者在 37 周后至 41 周期间出现自发性胎膜破裂。医生对患者进行了详细的病史、体格检查和妇科检查,然后将收集到的所有信息记录在事先设计好的表格上:结果:在 241 名 PROM 患者中,观察到 60 例母体并发症和 145 例胎儿并发症。在产妇并发症方面,28 例(46.7%)患者出现伤口感染,16 例(26.6%)患者出现少尿症,07 例(11.7%)患者因子宫内膜炎继发产褥热,09 例(15%)患者出现绒毛膜羊膜炎。约 56% 的产妇为顺产。胎儿结局方面,78 例(53.8%)患 RDS,35 例(24.1%)患高胆红素血症,23 例(16%)患新生儿败血症,09 例(6.2%)患坏死性小肠结肠炎。结论足月胎膜早破有可能导致胎儿和母体并发症。在保守治疗中延长妊娠期会增加胎儿和产妇的发病率,尤其是败血症。在这项研究中,我们得出结论,延长妊娠期的保守治疗对母亲和婴儿都有风险,只有在严格监测的情况下才推荐使用:绒毛膜羊膜炎 潜伏期 孕产妇结局 围产期结局 败血症
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引用次数: 0
Quality Control in Regional Blood Center QC Laboratory 地区血液中心质量控制实验室的质量控制
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.951
Syed Muzammil Shah
Implementing comprehensive quality control measures in Regional Blood Center (RBC) laboratory services is indispensable for ensuring the accuracy, reliability, and consistency of transfusion-transmitted infectious screening results. These measures not only identify and address potential issues but also uphold the highest standards in analysis and testing. Below, we explore deeper into the critical aspects of quality control in laboratory services especially in the Regional Blood Center laboratory followed by American association of blood banking. 
在地区血液中心(RBC)实验室服务中实施全面的质量控制措施,对于确保输血传播感染筛查结果的准确性、可靠性和一致性是不可或缺的。这些措施不仅能发现和解决潜在的问题,还能维护分析和检测的最高标准。下面,我们将按照美国血库协会的要求,深入探讨实验室服务质量控制的关键环节,尤其是地区血液中心实验室的质量控制。
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引用次数: 0
Impact of Prolonged Pregnancy on Mode of Delivery and Fetal Outcome 妊娠期延长对分娩方式和胎儿结局的影响
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.845
Faiza Rehman, Nasreen Kishwar, Rukhsana Karim, Shazia Khattak, Saman Mudassir
Background: The “term pregnancy” is defined as the pregnancy that ends between 259 and 294 days (37-42 weeks) of pregnancy from the 1st day of last menstrual period. If the pregnancy continues beyond this mentioned period, it is called prolonged pregnancy. Post-term Pregnancy is one of the commonest obstetric conditions which associated with an increased risk of fetal and neonatal mortality and morbidity as well as an increased maternal morbidity.Objectives: The aim of this study is to determine the frequency of mode of delivery and fetal outcomes in prolonged pregnancy.Material and Methods: It is a Descriptive cross sectional study, conducted from 28th Aug, 2019 to 28thFeb, 2020 at Department of Obs & Gynae, MTI-HMC Peshawar. Sample size was 125 keeping 11% proportion of patients having poor apgar score with 95% confidence interval, 5% level of significance.5% margin of error. Sample collection was accomplished by non-probability, consecutive sampling technique. All patients between 18-40 years of age with 42 weeks of gestation or more by dates or dating scan admitted to Gynae Ward/Labour room, having regular cycles were included in the study.Results: As per descriptive statistics, mean and SDs for age was 25±4.90. Mean and SDs for gravidity was recorded as 2±0.58. Mean and SDs for parity was 2±0.58. Mean and SDs for Apgar score was recorded as 8±0.89. 28 (22.4%) patients were obese. In this study 14 (11.2%) neonates had poor apgar score. Normal vaginal delivery 66(52.8%) was the Frequent mode of delivery followed by assisted vaginal deliveries 48(38.4%) and Caesarean section11(8.8%).Conclusion: In this study, we have concluded that pregnancy should not be allowed to go post-term due to association of higher neonatal morbidity and mortality rate, and should be managed before 42 weeks of gestation.Keywords: Fetal outcome, Post term pregnancy, Poor Apgar Score
背景:过期妊娠 "是指从末次月经第一天算起,妊娠在 259 天至 294 天(37-42 周)之间结束。如果妊娠持续超过上述期限,则称为过期妊娠。过期妊娠是最常见的产科疾病之一,会增加胎儿和新生儿的死亡率和发病率,并增加产妇的发病率:本研究旨在确定过期妊娠的分娩方式频率和胎儿结局:这是一项描述性横断面研究,于 2019 年 8 月 28 日至 2020 年 2 月 28 日在白沙瓦 MTI-HMC 妇产科进行。样本量为 125 个,其中 11% 的患者的 apgar 评分较低,置信区间为 95%,显著性水平为 5%,误差范围为 5%。样本收集采用非概率连续抽样技术。所有年龄在 18-40 岁之间、妊娠 42 周或以上(根据日期或日期扫描)、在妇科病房/产房住院、有正常生理周期的患者均被纳入研究范围:根据描述性统计,年龄的平均值和标差为 25±4.90。孕酮的平均值和标差为 2±0.58。胎次的平均值和标差为 2±0.58。Apgar评分的平均值和标码为8±0.89。28例(22.4%)患者肥胖。本研究中有 14 名(11.2%)新生儿的 Apgar 评分较低。正常阴道分娩 66 例(52.8%)是最常见的分娩方式,其次是阴道助产 48 例(38.4%)和剖腹产 11 例(8.8%):在这项研究中,我们得出结论,由于过期妊娠会导致新生儿发病率和死亡率升高,因此不应允许过期妊娠,应在妊娠42周之前进行处理:胎儿结局 过期妊娠 阿普加评分差
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引用次数: 0
The Efficacy of Phacotrabeculectomy in Reducing Intraocular Pressure 虹膜睫状体切除术在降低眼压方面的疗效
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.809
Zahir Khan Khalil, Shafqat Ali Shah, Amir Naseem, Saman Mudassir, Asif Mehmood Orakzai
Background: Primary open angle glaucoma and age related cataract are ocular comorbidities which can occur in some individuals at different times. Phacoemulsification is carried out for restoration of vision decreased by cataract while trabeculectomy is a procedure to decrease the intra ocular pressure. To save the time, money and stay in the hospital, phacotrabeculectomy is a single procedure which can fulfill both the restoration of vision and decrease intraocular pressure. Objectives: To determine the efficacy of phacotrabeculectomy in decreasing the intraocular pressure in patients having both primary open angle glaucoma and age related cataract.Materials and Methods: This study was conducted at the Eye department, Hayatabad Medical Complex, Peshawar, from 1st August, 2022 to 1st February 2023 after getting the permission from Ethical Committee to do this study. Patients both males and females, from 40-80 years of age, who had coexisting age related cataract (ARC) and Primary open angle glaucoma (POAG), whose intraocular pressures (IOP) was 21mm Hg or above, with and without using anti-glaucoma treatment.Patients who had secondary or rosette shaped cataract, past ocular trauma (including ocular surgery along with its intraoperative or post-operative complications) and trauma after phacotrabeculectomy procedure during the follow up period were excluded from this study.Results: All 121 patients underwent Phacotrabeculectomy. Follow up was done for 5 months. Preoperative mean intraocular pressure (IOP) was 23.53 ± 4.22SD which reduced to 12.90 ± 2.09SD postoperatively which was highly significant with p- value=0.001Conclusion: Phacotrabeculectomy reduced Intraocular pressure by >10 mm Hg in our study which showed that this procedure is very effective in coexisting age related cataract and primary open angle glaucoma.Keywords: Age related cataract, Angle closure glaucoma, Combined phaco-trabeculectomy, Glaucoma, Intraocular pressure, Open angle glaucoma, Trabeculectomy.
背景:原发性开角型青光眼和老年性白内障是眼部并发症,可在不同时期发生在某些人身上。实施超声乳化术是为了恢复因白内障而下降的视力,而小梁切除术则是为了降低眼压。为了节省时间、金钱和住院时间,超声乳化小梁切除术是一种既能恢复视力又能降低眼压的单一手术。研究目的确定虹膜睫状体切除术在降低原发性开角型青光眼和老年性白内障患者眼压方面的疗效:在获得伦理委员会的许可后,本研究于 2022 年 8 月 1 日至 2023 年 2 月 1 日在白沙瓦 Hayatabad Medical Complex 眼科进行。研究对象为年龄在 40-80 岁之间、同时患有年龄相关性白内障(ARC)和原发性开角型青光眼(POAG)、眼压(IOP)在 21 毫米汞柱或以上、接受或未接受抗青光眼治疗的男女患者。本研究排除了在随访期间患有继发性白内障或玫瑰状白内障、既往有眼外伤(包括眼部手术及其术中或术后并发症)以及虹膜睫状体切除术后眼外伤的患者:所有 121 名患者均接受了虹膜睫状体切除术。随访时间为 5 个月。术前平均眼压(IOP)为 23.53 ± 4.22SD,术后降至 12.90 ± 2.09SD,P 值=0.001,差异显著:在我们的研究中,法氏囊切除术降低眼压大于 10 mm Hg,这表明该手术对并存的老年性白内障和原发性开角型青光眼非常有效:老年性白内障 闭角型青光眼 联合超声乳化-小梁切除术 青光眼 眼压 开角型青光眼 小梁切除术
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引用次数: 0
Maternal Experience of Spinal Anesthesia for Cesarian Section, A Cross-Sectional Study 剖腹产脊髓麻醉的产妇体验,一项横断面研究
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.861
Nazish Hayat, Wajeeha Syed, Laila Zeb, Sidrah Yousafzai
Background: Cesarian section, an increasingly popular obstetric procedure, can be performed under general and regional anesthesia. Spinal anesthesia, a form of regional anesthesia has gained popularity over time due to its overall safety.Objectives: To study the maternal experience after going through cesarian under spinal anesthesia.Material and Methods: This was a cross sectional study carried out on admitted patients in Lady Reading Hospital, MTI, Peshawar. About 196 post-op admitted patients were selected by non-probability convenience sampling from 1st November 2023 till 15th December 2023. They were assessed with the help of questionnaire on their experience of spinal anesthesia on 3rd post cesarian day. Patents having had surgery under general anesthesia, primarily or secondarily, and those who had any additional procedure post operatively after cesarian were excluded. Data was analyzed on SPSS v23. Frequency and percentages were determined for categorical variables. Chi square test was applied for categorical variables with p value of <0.05 taken significant.Results: Of 196 patients, mean age of the participants was 29 ± 6 years, of whom 74 (37%) had elective and 122 (63%) had emergency cesarian section. Parity ranged from 1 to 13, with most parturients having parity in the range of 1-6. 90% of patients were satisfied with preoperative information provided. About 55% had nausea, 15% had dyspnea while 39% (n=77) had palpitation during the surgery. Nearly 18% did not like the feeling of being aware intraoperatively. However 98% (n=193) of patients were satisfied with responsiveness of anesthesia staff to their situation. About 105 (53%) patients affirmed that would like to have spinal anesthesia again in future if needed, 39% were unsure and 14 (7%) patients did not like it.Conclusion: Spinal anesthesia is an effective way of providing surgical anesthesia while maintaining high level of maternal satisfaction.Keywords: Cesarian section, Maternal satisfaction, Spinal anesthesia.
背景:剖腹产是一种日益流行的产科手术,可在全身麻醉和区域麻醉下进行。脊髓麻醉是区域麻醉的一种形式,因其整体安全性而逐渐受到欢迎:材料和方法:这是一项横断面研究:这是一项横断面研究,对象是白沙瓦MTI雷丁夫人医院的住院患者。从 2023 年 11 月 1 日至 2023 年 12 月 15 日,通过非概率方便抽样法选取了约 196 名术后住院患者。在调查问卷的帮助下,对他们在剖腹产后第三天的脊髓麻醉体验进行了评估。排除了主要或次要在全身麻醉下进行手术的患者,以及在剖腹产术后进行过其他手术的患者。数据使用 SPSS v23 进行分析。分类变量采用频数和百分比法。对分类变量采用卡方检验,P 值小于 0.05 为显著:在 196 名患者中,平均年龄为 29 ± 6 岁,其中 74 人(37%)为择期剖腹产,122 人(63%)为急诊剖腹产。胎次从 1 到 13 不等,大多数产妇的胎次在 1 到 6 之间。90%的患者对术前提供的信息表示满意。约 55% 的患者在手术中感到恶心,15% 的患者感到呼吸困难,39% 的患者(人数=77)在手术中感到心悸。近 18% 的患者不喜欢术中有知觉的感觉。然而,98%(n=193)的患者对麻醉人员对其情况的反应感到满意。约 105 名(53%)患者表示,如果有需要,他们愿意在今后再次接受脊髓麻醉,39% 的患者表示不确定,14 名(7%)患者表示不喜欢:结论:脊髓麻醉是一种有效的手术麻醉方式,同时能保持较高的产妇满意度:剖腹产 产妇满意度 脊髓麻醉
{"title":"Maternal Experience of Spinal Anesthesia for Cesarian Section, A Cross-Sectional Study","authors":"Nazish Hayat, Wajeeha Syed, Laila Zeb, Sidrah Yousafzai","doi":"10.52206/jsmc.2024.14.2.861","DOIUrl":"https://doi.org/10.52206/jsmc.2024.14.2.861","url":null,"abstract":"Background: Cesarian section, an increasingly popular obstetric procedure, can be performed under general and regional anesthesia. Spinal anesthesia, a form of regional anesthesia has gained popularity over time due to its overall safety.Objectives: To study the maternal experience after going through cesarian under spinal anesthesia.Material and Methods: This was a cross sectional study carried out on admitted patients in Lady Reading Hospital, MTI, Peshawar. About 196 post-op admitted patients were selected by non-probability convenience sampling from 1st November 2023 till 15th December 2023. They were assessed with the help of questionnaire on their experience of spinal anesthesia on 3rd post cesarian day. Patents having had surgery under general anesthesia, primarily or secondarily, and those who had any additional procedure post operatively after cesarian were excluded. Data was analyzed on SPSS v23. Frequency and percentages were determined for categorical variables. Chi square test was applied for categorical variables with p value of <0.05 taken significant.Results: Of 196 patients, mean age of the participants was 29 ± 6 years, of whom 74 (37%) had elective and 122 (63%) had emergency cesarian section. Parity ranged from 1 to 13, with most parturients having parity in the range of 1-6. 90% of patients were satisfied with preoperative information provided. About 55% had nausea, 15% had dyspnea while 39% (n=77) had palpitation during the surgery. Nearly 18% did not like the feeling of being aware intraoperatively. However 98% (n=193) of patients were satisfied with responsiveness of anesthesia staff to their situation. About 105 (53%) patients affirmed that would like to have spinal anesthesia again in future if needed, 39% were unsure and 14 (7%) patients did not like it.Conclusion: Spinal anesthesia is an effective way of providing surgical anesthesia while maintaining high level of maternal satisfaction.Keywords: Cesarian section, Maternal satisfaction, Spinal anesthesia.","PeriodicalId":326561,"journal":{"name":"Journal of Saidu Medical College, Swat","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140678707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-Tonsillectomy Pain:Is Cold Steel Dissection Method or Bipolar Diathermy Dissection Method is less Painful? 扁桃体切除术后疼痛:冷钢剥离法和双极透热剥离法疼痛更轻?
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.804
Muhammad Usman, Naveed Khan, Shafiq Ahmad, Inayat Ullah, Ubaidullah, Ashfaq Hussain
Back ground: Pain is one of the sequel of tonsillectomy, as reported in various studies. Tonsillectomy can be done by various methods, so aim of the present study is to evaluate pain of tonsillectomy comparing cold steel dissection method with bipolar diathermy method.Objective: To evaluate post-tonsillectomy pain comparing cold steel dissection method with bipolar diathermy method.Material and Methods: This prospective, randomized, controlled trial was conducted in ENT Department, from 18th January 2021 to January 30th 2022. Post tonsillectomy pain was measured by using visual analogue scale which consists of a 10 cm line with score of 10 means worse pain and score of zero means no pain. In this study a total sample size was 186 patients (i.e. 93 in each group), who were observed by taking the following parameters. Mean ± SD of group A (bipolar diathermy group) = 2.27 ± 1.25. Mean ± SD of group B (cold steel dissection group) = 1.59 ± 1.59. Confidence interval (2-sided) =95%. Power=90%. More over consecutive (nonprobability) sampling technique was used for sample collection.Results: In bipolar dissection group (38%) patients were male and (62%) patients were female. Where as in cold dissection group (40%) patients were male and (60%) patients were female. The mean pain score at 24 hours, 2ndpost operative day, 7th post operative day among two groups was analyzed. In bipolar dissection group, mean pain score at 24 hours was 3.5 ± 0.66, mean pain score at 2nd post operative day was 2.93 ± 0.73 and mean pain score at 7th post operative was 1.59 ± 1.02. Where as in cold dissection group, mean pain score at 24 hours was 3.33 ± 0.53 with a p value of 0.0543, mean pain score at 2ndpost operative day was 2.34 ± 0.60 with a p value of 0.0001and mean pain score at 7th post operative was 1.46 ± 0.82 with a p value of 0.3394.Conclusion: Our study concludes that mean pain score is less in cold steel dissection tonsillectomy as compared to bipolar diathermy tonsillectomy.Keywords: Analogue pain scale, Surgical Diathermy, Tonsillectomy.
背景:疼痛是扁桃体切除术的后遗症之一,这在多项研究中均有报道。扁桃体切除术可采用多种方法,因此本研究的目的是评估扁桃体切除术后的疼痛,并对冷钢剥离法与双极透热法进行比较:比较冷钢剥离法与双极透热法,评估扁桃体切除术后的疼痛:这项前瞻性、随机对照试验于 2021 年 1 月 18 日至 2022 年 1 月 30 日在耳鼻喉科进行。扁桃体切除术后疼痛采用视觉模拟量表进行测量,量表由一条 10 厘米长的线组成,10 分表示疼痛加重,0 分表示无痛。本研究的总样本量为 186 例患者(即每组 93 例),通过以下参数对其进行观察。A 组(双极电疗组)的平均值(± SD)= 2.27 ± 1.25。B组(冷钢剥离组)的平均±标准差 = 1.59 ± 1.59。置信区间(双侧)=95%。功率=90%。样本收集采用连续(非概率)抽样技术:双极剥离组(38%)患者为男性,(62%)患者为女性。而在冷剥离组中,男性患者占 40%,女性患者占 60%。分析了两组患者在术后 24 小时、术后第 2 天和术后第 7 天的平均疼痛评分。在双极剥离组,24 小时的平均疼痛评分为 3.5 ± 0.66,术后第 2 天的平均疼痛评分为 2.93 ± 0.73,术后第 7 天的平均疼痛评分为 1.59 ± 1.02。而在冷剥离组中,24 小时的平均疼痛评分为 3.33 ± 0.53,P 值为 0.0543;术后第 2 天的平均疼痛评分为 2.34 ± 0.60,P 值为 0.0001;术后第 7 天的平均疼痛评分为 1.46 ± 0.82,P 值为 0.3394:我们的研究得出结论,与双极透热扁桃体切除术相比,冷钢剥离扁桃体切除术的平均疼痛评分较低:模拟疼痛量表 外科热疗扁桃体切除术
{"title":"Post-Tonsillectomy Pain:Is Cold Steel Dissection Method or Bipolar Diathermy Dissection Method is less Painful?","authors":"Muhammad Usman, Naveed Khan, Shafiq Ahmad, Inayat Ullah, Ubaidullah, Ashfaq Hussain","doi":"10.52206/jsmc.2024.14.2.804","DOIUrl":"https://doi.org/10.52206/jsmc.2024.14.2.804","url":null,"abstract":"Back ground: Pain is one of the sequel of tonsillectomy, as reported in various studies. Tonsillectomy can be done by various methods, so aim of the present study is to evaluate pain of tonsillectomy comparing cold steel dissection method with bipolar diathermy method.Objective: To evaluate post-tonsillectomy pain comparing cold steel dissection method with bipolar diathermy method.Material and Methods: This prospective, randomized, controlled trial was conducted in ENT Department, from 18th January 2021 to January 30th 2022. Post tonsillectomy pain was measured by using visual analogue scale which consists of a 10 cm line with score of 10 means worse pain and score of zero means no pain. In this study a total sample size was 186 patients (i.e. 93 in each group), who were observed by taking the following parameters. Mean ± SD of group A (bipolar diathermy group) = 2.27 ± 1.25. Mean ± SD of group B (cold steel dissection group) = 1.59 ± 1.59. Confidence interval (2-sided) =95%. Power=90%. More over consecutive (nonprobability) sampling technique was used for sample collection.Results: In bipolar dissection group (38%) patients were male and (62%) patients were female. Where as in cold dissection group (40%) patients were male and (60%) patients were female. The mean pain score at 24 hours, 2ndpost operative day, 7th post operative day among two groups was analyzed. In bipolar dissection group, mean pain score at 24 hours was 3.5 ± 0.66, mean pain score at 2nd post operative day was 2.93 ± 0.73 and mean pain score at 7th post operative was 1.59 ± 1.02. Where as in cold dissection group, mean pain score at 24 hours was 3.33 ± 0.53 with a p value of 0.0543, mean pain score at 2ndpost operative day was 2.34 ± 0.60 with a p value of 0.0001and mean pain score at 7th post operative was 1.46 ± 0.82 with a p value of 0.3394.Conclusion: Our study concludes that mean pain score is less in cold steel dissection tonsillectomy as compared to bipolar diathermy tonsillectomy.Keywords: Analogue pain scale, Surgical Diathermy, Tonsillectomy.","PeriodicalId":326561,"journal":{"name":"Journal of Saidu Medical College, Swat","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140679220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Zinc and Copper Levels in Children with Thalassemia Major 重型地中海贫血症儿童的血清锌和铜水平
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.302
Mian Muhammad Naveed, Shabir Ahmed Orakzai, Siyab Ahmad, Mohibullah Khan, Asfandyar Shah Roghani, Humaira Khan
Background: Thalassemia is a frequent hereditary genetic with different clinical manifestations from mild to severe based on its genetic. Beta thalassemia major is the worse form of this disease caused by decreased or absent beta globin chains of hemoglobin. Regular blood transfusion is the main aim leads to iron overload and deposition of iron in different organs.Objectives: To determine different serum distribution levels and correlation of copper and zinc in transfusion dependent thalassemia patients Material and Methods: This was a descriptive cross-sectional study in which a non-probability convenient sampling technique was used for sample collection. This study was conducted in KPK in a total of 137 patients, who were diagnosed cases of thalassemia major by hemoglobin electrophoresis, enzyme linked immunosorbent assay (ELISA) method and receiving iron and folate therapy. SPSS version 22 was used and Pearson's correlation coefficient was applied. P-value 0.05 was considered significant.Results: In this study mean age was 6.7±3.49 years. 77 (56%) percent children were male while 64 (44%) children were female. Mean hemoglobin (Hb) level was 7.43±1.3 gm/dl. Mean SGPT score was 26.28 ± 7.51. Mean blood urea was 21.10 ± 8.49 mmol/l while mean serum creatinine level was 0.56 ± 0.26 mg/dl. Mean serum zinc level was 13.36 ± 11.12mg/dl while mean serum copper level was 1.21± 0.60 mg/dl and mean serum ferritin level was 6682 ± 533 Ug/l.Conclusion: This study showed hypozincemia in thalassemia major patients, but copper deficit was not present. There was no substantial variance between serum ferritin level and mean serum concentration of zinc and copper in this study. Ancillary assessments in this respect is recommended. Keywords: Copper, Thalassemia, Zinc
背景:地中海贫血是一种常见的遗传性疾病,其临床表现因遗传基因不同而有轻重之分。重型β地中海贫血是由于血红蛋白的β球蛋白链减少或缺失而导致的最严重的疾病。定期输血是导致铁超载和铁在不同器官沉积的主要原因:确定输血依赖型地中海贫血患者的不同血清分布水平以及铜和锌的相关性:这是一项描述性横断面研究,采用非概率方便抽样技术收集样本。这项研究在库尔德斯坦进行,共有 137 名患者通过血红蛋白电泳、酶联免疫吸附试验(ELISA)方法确诊为重型地中海贫血,并正在接受铁和叶酸治疗。研究使用 SPSS 22 版,并采用了皮尔逊相关系数。P 值 0.05 为显著:本研究的平均年龄为(6.7±3.49)岁。77%(56%)的儿童为男性,64%(44%)的儿童为女性。平均血红蛋白(Hb)水平为(7.43±1.3)克/分升。平均 SGPT 评分为 26.28±7.51 分。平均血尿素(21.10±8.49)毫摩尔/升,平均血清肌酐(0.56±0.26)毫克/分升。平均血清锌水平为(13.36 ± 11.12)毫克/分升,平均血清铜水平为(1.21 ± 0.60)毫克/分升,平均血清铁蛋白水平为(6682 ± 533)乌克/升:本研究显示重型地中海贫血患者存在低锌血症,但不存在铜缺乏。在这项研究中,血清铁蛋白水平与锌和铜的平均血清浓度之间没有实质性差异。建议在这方面进行辅助评估。关键词铜 地中海贫血症 锌
{"title":"Serum Zinc and Copper Levels in Children with Thalassemia Major","authors":"Mian Muhammad Naveed, Shabir Ahmed Orakzai, Siyab Ahmad, Mohibullah Khan, Asfandyar Shah Roghani, Humaira Khan","doi":"10.52206/jsmc.2024.14.2.302","DOIUrl":"https://doi.org/10.52206/jsmc.2024.14.2.302","url":null,"abstract":"Background: Thalassemia is a frequent hereditary genetic with different clinical manifestations from mild to severe based on its genetic. Beta thalassemia major is the worse form of this disease caused by decreased or absent beta globin chains of hemoglobin. Regular blood transfusion is the main aim leads to iron overload and deposition of iron in different organs.Objectives: To determine different serum distribution levels and correlation of copper and zinc in transfusion dependent thalassemia patients Material and Methods: This was a descriptive cross-sectional study in which a non-probability convenient sampling technique was used for sample collection. This study was conducted in KPK in a total of 137 patients, who were diagnosed cases of thalassemia major by hemoglobin electrophoresis, enzyme linked immunosorbent assay (ELISA) method and receiving iron and folate therapy. SPSS version 22 was used and Pearson's correlation coefficient was applied. P-value 0.05 was considered significant.Results: In this study mean age was 6.7±3.49 years. 77 (56%) percent children were male while 64 (44%) children were female. Mean hemoglobin (Hb) level was 7.43±1.3 gm/dl. Mean SGPT score was 26.28 ± 7.51. Mean blood urea was 21.10 ± 8.49 mmol/l while mean serum creatinine level was 0.56 ± 0.26 mg/dl. Mean serum zinc level was 13.36 ± 11.12mg/dl while mean serum copper level was 1.21± 0.60 mg/dl and mean serum ferritin level was 6682 ± 533 Ug/l.Conclusion: This study showed hypozincemia in thalassemia major patients, but copper deficit was not present. There was no substantial variance between serum ferritin level and mean serum concentration of zinc and copper in this study. Ancillary assessments in this respect is recommended. Keywords: Copper, Thalassemia, Zinc","PeriodicalId":326561,"journal":{"name":"Journal of Saidu Medical College, Swat","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140678416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appendectomy Open Versus Laparoscopic in Developing World Scenario 发展中国家阑尾切除术的开腹与腹腔镜手术
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.782
Saif Ud Din Awan, Ayesha Naureen Awan, Nadia Haleem, Hina Fayyaz
Background: Laparoscopic surgery is an expanding field which is recognized as gold standard for cholecystectomy, it is being increasingly used by many surgical subspecialties with advantage of being minimal invasive and being both diagnostic and therapeutic. Objectives: This study was done to evaluate the feasibility of laparoscopic appendectomy in a developing world scenario.Material and Methods: This observational cross-sectional study was conducted under department of general surgery from September 2019 to August 2021. The patients presenting to the ER department were evaluated based on Alvarado score. Alternate patients underwent laparoscopic appendectomy (LA) and open appendectomy (OA). Based upon clinical and imaging signs of acute appendicitis (i.e. Alvarado score of 7 or more) and consent to be the part of study, were used as inclusion criteria, while pregnancy, patients who could not tolerate increased intra-abdominal pressure/prolonged anesthesia, patients under 10 years of age and patients with evidence of appendicular mass formation were excluded from the study. The standard surgical techniques were performed for both groups and the patients were followed up in immediate post-operative period, at 6 months and one year. Results: The parameters observed were duration of surgery average 25 minutes (range 15-50 mins) for OA and 70 minutes (range 40-90 mins) for LA (P-Value 1.41E-70), return to preoperative activity level was 13 days (range 10-17 days) for OA and 10 days (range 9-14 days) for LA (P-Value 6.69034E-22), and average cost for OA was PKR 35279.00 while for LA was PKR 72168.00 (P-Value 1.24442E-60). Remaining parameters were not significantly different.Conclusion: The evidence available clearly demonstrates that laparoscopic appendectomy is superior to open appendectomy in terms of hospital stay, post-operative pain and return to work, however in a few situations the procedure needs to be converted therefore the surgeon must be conversant with open appendectomy for complicated case. Moreover, cost is a major factor determining the choice of procedure specially in the developing countries. Keywords: Appendectomy, Developing world, Laparoscopic Appendectomy, Open versus Laparoscopic Appendectomy, Pakistan,
背景:腹腔镜手术是一个不断扩展的领域,被公认为胆囊切除术的金标准,它具有微创、诊断和治疗的优势,正被越来越多的外科亚专科采用。研究目的本研究旨在评估腹腔镜阑尾切除术在发展中国家的可行性:本观察性横断面研究于 2019 年 9 月至 2021 年 8 月在普外科进行。根据阿尔瓦拉多评分对急诊科就诊患者进行评估。备用患者接受腹腔镜阑尾切除术(LA)和开腹阑尾切除术(OA)。根据急性阑尾炎的临床和影像学征兆(即 Alvarado 评分 7 分或以上)和同意参与研究作为纳入标准,而妊娠、不能耐受腹内压升高/长时间麻醉的患者、10 岁以下的患者和有阑尾肿块形成证据的患者则被排除在研究之外。两组患者均采用标准手术技术,并在术后即刻、6 个月和 1 年对患者进行随访。结果:观察到的参数包括:OA 的手术时间平均为 25 分钟(15-50 分钟不等),LA 的手术时间平均为 70 分钟(40-90 分钟不等)(P-Value 1.41E-70);OA 恢复到术前活动水平的时间为 13 天(10-17 天不等),LA 恢复到术前活动水平的时间为 10 天(9-14 天不等)(P-Value 6.69034E-22);OA 的平均费用为 35279.00 卢比,LA 的平均费用为 72168.00 卢比(P-Value 1.24442E-60)。其余参数无明显差异:现有证据清楚地表明,腹腔镜阑尾切除术在住院时间、术后疼痛和重返工作岗位方面优于开腹阑尾切除术,但在少数情况下需要转换手术方式,因此外科医生必须熟悉复杂病例的开腹阑尾切除术。此外,费用也是决定手术选择的一个主要因素,尤其是在发展中国家。关键词阑尾切除术 发展中国家 腹腔镜阑尾切除术 开腹与腹腔镜阑尾切除术 巴基斯坦
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引用次数: 0
Dual-Task Specific Training or Conventional Physiotherapeutic Interventions, Which one is more Effective? 双重任务专项训练与传统物理治疗干预,哪个更有效?
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.821
Nisaruddin, Muslim Khan, Saima Rahman, Iqra Muslim
Background: Physiotherapeutic interventions play a crucial role in motor re-learning and functional recovery for stroke patients with upper and lower limb motor impairments. Among these interventions, dual-task training (DTT) has demonstrated significant effectiveness in enhancing the functional recovery of stroke patients. Objective: This study aims to compare the effectiveness of DTT and conventional physical therapy in ambulating right-hemiplegic stroke patients.Material and Methods: A randomized control trial (RCT) was conducted at the Department of Rehabilitation Medicine, Saidu group of Teaching Hospital, 2nd March 2020 to 3rd August 2020. Chronic right-hemiplegic stroke patients meeting set inclusion criteria were randomly assigned to two groups: the treatment group (TG) receiving DTT and the control group (CG) undergoing conventional physical therapy. DTT interventions included walking forward, backward, and sideways on a smooth surface while holding an 80-gram sandbag. The CG received conventional physiotherapy involving mat activities, strengthening, stretching exercises, and ambulation/gait training. Pre- and post-tests collected clinical data analyzed on SPSS 22 included spatial and temporal variables, 10-Meter Walk Test (10MWT), Time Up & Go Test (TUG), step length, cadence, cycle time, and stride length. Results: Out of 18 patients, each group had 50%, comprising 5 males (28%) and 4 females (22%). The mean age in CG was 57.20± 5.20, and in TG, it was 57.27± 6.10 years. Baseline clinical parameters were nearly identical between groups (P>0.05). Post-test scores revealed significant improvements in spatial and temporal gait variables, 10MWT score, cadence, step length, stride, and cycle time in TG compared to CG (P<0.05). Conclusion: Dual-task training and conventional physical therapy both significantly enhance the functional ability of right-hemiplegic patients across all gait temporal and spatial parameters. Keywords: Conventional physical therapy, Dual task training, Gait & ambulation, Stroke.
背景:物理治疗干预措施对有上下肢运动障碍的中风患者的运动再学习和功能恢复起着至关重要的作用。在这些干预措施中,双任务训练(DTT)在促进中风患者的功能恢复方面具有显著效果。研究目的本研究旨在比较双任务训练和传统物理疗法对右偏瘫脑卒中患者步行的有效性:这项随机对照试验于 2020 年 3 月 2 日至 2020 年 8 月 3 日在赛都教学医院康复医学科进行。符合既定纳入标准的慢性右侧偏瘫中风患者被随机分配到两组:治疗组(TG)接受 DTT,对照组(CG)接受常规物理治疗。DTT 的干预措施包括手持 80 克重的沙袋,在光滑的地面上向前、向后和向两侧行走。对照组(CG)则接受常规物理治疗,包括垫上运动、强化、伸展运动和行走/步态训练。通过 SPSS 22 分析收集的前测和后测临床数据包括空间和时间变量、10 米步行测试(10MWT)、步行时间测试(TUG)、步长、步幅、周期时间和步长。结果显示在 18 名患者中,每组 50%,包括 5 名男性(28%)和 4 名女性(22%)。CG的平均年龄为(57.20± 5.20)岁,TG的平均年龄为(57.27± 6.10)岁。两组的基线临床参数几乎相同(P>0.05)。测试后的评分显示,TG 与 CG 相比,在空间和时间步态变量、10MWT 评分、步幅、步长、步幅和周期时间方面均有明显改善(P<0.05)。结论双任务训练和传统物理疗法都能显著提高右侧偏瘫患者在所有步态时空参数方面的功能能力。关键词传统物理治疗 双任务训练 步态与行走 中风
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引用次数: 0
Preventable Male Infertility: Identifying the Modifiable Risk Factors 可预防的男性不育:确定可改变的风险因素
Pub Date : 2024-04-21 DOI: 10.52206/jsmc.2024.14.2.833
Nighat Musa, Waseeq Ullah, Naeemullah, Rubeena Gul, Aziza Alam, Sherbaz Khan
Background: Infertility is a global health issue, with both genders having equal contribution. Approximately 15% of couples having difficulty to conceive after one year of consistent, unprotected sexual activity, infertility. Objectives: To identify the modifiable risk factors of male infertility in patients visiting a private hospital of Peshawar.Material and Methods: The study was a descriptive Cross-sectional of six months duration. A total sample size of 733 married male patients visiting private hospital were included and those who were reluctant to participate were excluded. Structured questionnaire were filled. Non probability convenience sampling technique was used and data was analyzed using SPSSversion 22Results: Out of 733 sample size 397(54%),336 (45.9%) had secondary and primary infertility, respectively. Risk factors, like obesity, smoking, diabetes mellitus, congenital anomalies and varicocele were linked to infertility with p valve < 0.05. The majority 568 (77.5%) had normal semen count, Oligospermia and Azoospermia were 11%.Conclusion: Our study concluded that smoking, diabetes mellitus, obesity, semen abnormalities and congenital anomalies were related to both primary and secondary infertility among men in Peshawar.Keywords: Male infertility, Obesity, Risk factors, Semen analysis, Semen abnormalities, Tobacco use.
背景:不孕症是一个全球性的健康问题,男女双方都有同样的责任。大约 15%的夫妇在持续一年的无保护性活动后难以受孕。研究目的在白沙瓦一家私立医院就诊的男性不育症患者中确定可改变的风险因素:本研究为描述性横断面研究,为期六个月。共有 733 名到私立医院就诊的已婚男性患者被纳入样本,不愿意参与的患者被排除在外。填写了结构化问卷。研究采用了非概率方便抽样技术,并使用 SPSSversion 22 对数据进行了分析:在 733 个样本中,397 人(54%)和 336 人(45.9%)分别患有继发性和原发性不孕症。肥胖、吸烟、糖尿病、先天性畸形和精索静脉曲张等风险因素与不孕症有关,P 值小于 0.05。大多数 568 人(77.5%)精液计数正常,少精症和无精症占 11%:我们的研究得出结论,在白沙瓦的男性中,吸烟、糖尿病、肥胖、精液异常和先天性异常与原发性和继发性不育有关:男性不育 肥胖 危险因素 精液分析 精液异常 吸烟
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引用次数: 0
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Journal of Saidu Medical College, Swat
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