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Association of Increased Neutrophil to Lymphocyte Ratio to in-Hospital Outcome of Acute anterior Myocardial Infarction Patients Subjected to Thrombolytic Therapy with Streptokinase 急性前路心肌梗死患者接受链激酶溶栓治疗后中性粒细胞与淋巴细胞比值升高与住院预后的关系
Pub Date : 2022-06-14 DOI: 10.52206/jsmc.2022.12.2.694
Habib Ur Razaq, Dr Khurshid Ali, Aqsa
Background: Myocardial infarction mainly contributes to morbidity and mortality around the globe. Thrombolytic therapy with streptokinase is the primary treatment strategy for patients with the presentation of ST-segment-elevated acute myocardial Infarction. Objective: To assess to assess the correlation between increased NLR and in-hospital outcome in acute anterior MI patients subjected to streptokinase therapy. Material and Methods: The study was a retrospective cohort conducted over a period of six months from 01, 06, 2021 to 30, 11, and 2021. All the patients admitted consecutively during this period received streptokinase therapy. The patients were grouped with respect to NLR, i.e., high NLR ang low NLR. The cut-off point for dividing into these two groups was set as 4.50 as an average of studies previously conducted. The study endpoints in-hospital outcomes and the secondary end point was short-term mortality.Results: A total of 250 patients were presented with acute MI. Complications were reported in 115 patients (46%) whereas 46 deaths (18.4%) were reported. More complications were reported in patients present in the group with higher NLR, (n=83 vs. 27, 62.8 % vs. 22.8 %, p <0.0001), as well as death (n=35 vs. 11, 26.5 % vs. 9.3 %, p<0.0001) in hospital compared to the group with lower NLR. Conclusion: high NLR (using 4.50 as cut-off value) is in association with a higher rate of complicatxions and death during stay in the hospital in acute MI patients which are subjected to streptokinase. Key Words: Myocardial infarction, Thrombolytic therapy, Streptokinase, Neutrophil, Lymphocyte.
背景:心肌梗死是全球范围内发病率和死亡率的主要原因。链激酶溶栓治疗是st段抬高急性心肌梗死患者的主要治疗策略。目的:评价急性前路心肌梗死患者接受链激酶治疗后NLR升高与住院预后的相关性。材料和方法:该研究是一项回顾性队列研究,为期6个月,从2021年1月、6月到2021年30日、11日和2021年。在此期间连续入院的患者均接受链激酶治疗。患者根据NLR进行分组,即高NLR和低NLR。这两组的分界点被设定为4.50,这是之前进行的研究的平均值。研究终点是院内结局,次要终点是短期死亡率。结果:共有250例患者出现急性心肌梗死,其中115例(46%)出现并发症,46例(18.4%)死亡。与低NLR组相比,高NLR组的患者出现了更多的并发症(n=83 vs. 27,62.8% vs. 22.8%, p<0.0001),以及住院死亡(n=35 vs. 11,26.5% vs. 9.3%, p<0.0001)。结论:高NLR(以4.50作为临界值)与接受链激酶治疗的急性心肌梗死患者住院期间较高的并发症发生率和死亡率相关。关键词:心肌梗死,溶栓治疗,链激酶,中性粒细胞,淋巴细胞。
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引用次数: 0
Effects of Exercise on various Systems of Human Body in residence of Peshawar Khyber Pakhtunkhwa, Pakistan 巴基斯坦白沙瓦开伯尔-普赫图赫瓦居民运动对人体各系统的影响
Pub Date : 2022-06-14 DOI: 10.52206/jsmc.2022.12.2.633
Asna Tahir, Ahrar Sikander, Sabawoon Hayat, Saud Azhar, Kashif ur Rehman Khalil, Saad Zahoor
Background: Non Communicable diseases like hypertension, diabetes and heart diseases are on rise due to sedentary lifestyle. Exercise is the most import factor that can improve outcome of major communicable diseases.Objective: To evaluate the beneficial effects of exercise on human body as perceived by individuals.Material and Methods: Study was conducted from 1st September 2019 to 28 February 2020 in community of Peshawar KP. A sample size of 300 individuals were selected using non probability convenient sampling technique. Data was collected on a structured questionnaire which was prevalidated through pilot study. Results: Mean age of study participants were 33 ± 5 S.D. Majority of the study participants were male (73%) and remaining were females (27%). 33% reported that they exercise every day,18% once in a week.27% 3 times a week and 22% of study participants reported that they do exercise occasionally.Participants were asked about effect of exercise on blood pressure and other parameters. Those who were hypertensive reported an improvement in blood pressure after starting regular exercise. The study subjects were asked about the effect of exercise on GIT function. Majority reported improvement in gastrointestinal function. Reduction in weight and improvement in other systems were also reported as shown significance with a P-value less than 0.05.Conclusions: Our study concluded that those individuals who started regular exercise have reported significant improvement in their different body functions. Therefore there is significant importance of exercising regularly in maintaining a sound mind and a sound body.Key words: Exercise, BMI, Hypertension, Diabetes
背景:由于久坐不动的生活方式,高血压、糖尿病和心脏病等非传染性疾病呈上升趋势。运动是改善重大传染病转归的最重要因素。目的:评价运动对人体的有益作用。材料和方法:研究于2019年9月1日至2020年2月28日在KP白沙瓦社区进行。采用非概率方便抽样法,选取300人作为样本。数据收集在一个结构化的问卷上,通过试点研究预先验证。结果:研究参与者的平均年龄为33±5 S.D.,大多数研究参与者为男性(73%),其余为女性(27%)。33%的人每天锻炼,18%的人每周锻炼一次。27%的人每周锻炼3次,22%的人偶尔锻炼。参与者被问及运动对血压和其他参数的影响。那些患有高血压的人在开始定期锻炼后血压有所改善。研究对象被问及运动对GIT功能的影响。大多数报告了胃肠道功能的改善。其他系统的体重减轻和改善也显示出显著性,p值小于0.05。结论:我们的研究得出结论,那些开始定期锻炼的人,他们的各种身体机能都有了显著的改善。因此,经常锻炼对于保持健康的身心是非常重要的。关键词:运动,BMI,高血压,糖尿病
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引用次数: 0
Identification of Bullying Behaviours and Coping Strategies of Postgraduate Trainees in Clinical Settings 临床环境下研究生受欺负行为的识别与应对策略
Pub Date : 2022-06-14 DOI: 10.52206/jsmc.2022.12.2.700
Jibran Umar Ayub, Brekhna Jamil, Ayesha Qaisar, Umar Ayub Khan, Azhar Zahir Shah
Background: Despite the world over recognition of bullying it still remains an understudied area which needs further research. Furthermore, the administrations and heads of departments are reluctant to acknowledge that there is occurrence bullying in their institution.Objective: To identify bullying behaviors experienced by post graduate residents in clinical environment and the strategies used for coping with them.Material and Methods:  A total of 355 participants were taken. Two tools were used to collect the necessary data, consisted of three parts:Negative Acts Questionnaire,Brief COPE Inventory; and a demographic sheet. Results: There were 125(35.21%) participants who were used to giving up the attempt to cope, I've been getting emotional support from others was told by 116(32.67%), I've been blaming myself for things that happened was reportedby 111(31.26%), I've been criticizing myself was told by 107(30.14%). Others coping strategies (now and then, monthly, weekly daily) were identified as praying or meditating by 295(83.09%) participants, learning to live with it by 291(81.97%) and thinking hard about what steps to take by 291(81.97). The bullying behaviors experienced by residents were having your opinions and views ignored were reported by 259(72.95%), 247(69.57%) told about being ordered to do work below your level of competence, blaming myself for things that happened for 244(68.73%), repeated reminders of your errors or mistakes by 239(67.32%). Conclusion: It is concluded that bullying is major problem and must be minimized in new residents by making it part of curriculum or polices of various institutions. Keywords: Workplace, bullying, mental torture, workload, residents.
背景:尽管全世界都认识到欺凌行为,但它仍然是一个研究不足的领域,需要进一步研究。此外,行政部门和部门负责人不愿意承认他们的机构中存在欺凌现象。目的:了解住院医师研究生在临床环境中的欺凌行为及其应对策略。材料与方法:共选取355名受试者。使用两种工具收集必要的数据,包括三部分:负面行为问卷,简短的COPE量表;还有一份人口统计表。结果:有125人(35.21%)习惯于放弃应对的尝试,116人(32.67%)说我一直得到别人的情感支持,111人(31.26%)说我一直对发生的事情自责,107人(30.14%)说我一直在批评自己。其他应对策略(偶尔、每月、每周、每天)有295人(83.09%)认为是祈祷或冥想,有291人(81.97%)认为是学会忍受,有291人(81.97)认为是努力思考该采取什么步骤。居民遭受的欺凌行为有259人(72.95%)被忽视,247人(69.57%)被要求做低于自己能力水平的工作,244人(68.73%)因发生的事情责备自己,239人(67.32%)被反复提醒自己的错误或错误。结论:校园霸凌是学校的主要问题,必须将其纳入学校的课程或政策中,以减少校园霸凌。关键词:工作场所,欺凌,精神折磨,工作量,居民
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引用次数: 0
Comparison of Postoperative Complications Early Vs Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis 急性胆囊炎早期与延迟腹腔镜胆囊切除术术后并发症的比较
Pub Date : 2022-06-14 DOI: 10.52206/jsmc.2022.12.2.664
M. Yousaf, M. Shah, Shahid Afridi
Background: Acute cholecystitis, which is typically associated with gallstones, is one of the most common causes of acute abdomen presenting in emergency departments around the world. The aim of this study was to compare the incidence of biliary leak and hospital stay between early and delayed laparoscopic cholecystectomy for acute cholecystitis.Objectives: To compare the incidence of biliary leak and hospital stay between early and delayed laparoscopic cholecystectomy for acute cholecystitis.Material and Methods: Patients with radiologically confirmed acute calculus cholecystitis and ASA grade I/II were selected from the surgical OPD and prospectively randomized into two equivalent classes between August 1, 2015 and July 31, 2017. Early laparoscopic cholecystectomy was performed on patients in group A, while delayed laparoscopic cholecystectomy was performed on patients in group B. The data was collected from the patients using a non-probability sampling technique.Results: The research included 200 patients with radiologically proven acute calculus cholecystitis and an ASA grade I/II. Overall, patients who had an early laparoscopic cholecystectomy had a shorter hospital stay and less billary leak than those who had a delayed laparoscopic cholecystectomy (P=0.01) (0.00 and 0.11). In comparison to Group-II, the number of post-operative complications was lower in Group-I.Conclusion: When compared to delayed laparoscopic cholecystectomy, early laparoscopic cholecystectomy allows for substantially shorter biliary leak frequency and overall hospital stay.Key Words: Acute cholecystitis, Cholecystectomy, Laparoscopic.
背景:急性胆囊炎通常与胆结石相关,是世界各地急诊科急性腹部最常见的原因之一。本研究的目的是比较急性胆囊炎早期和延迟腹腔镜胆囊切除术的胆漏发生率和住院时间。目的:比较急性胆囊炎早期和延迟腹腔镜胆囊切除术的胆漏发生率和住院时间。材料与方法:选择2015年8月1日至2017年7月31日期间,从外科OPD中选择影像学证实的急性结石性胆囊炎,ASA分级为I/II级的患者,前瞻性随机分为两个等效组。A组患者行早期腹腔镜胆囊切除术,b组患者行延迟腹腔镜胆囊切除术。数据采集采用非概率抽样技术。结果:本研究纳入200例影像学证实的急性结石性胆囊炎患者,ASA分级为I/II级。总的来说,早期腹腔镜胆囊切除术的患者比延迟腹腔镜胆囊切除术的患者住院时间更短,胆漏更少(P=0.01)(0.00和0.11)。与ii组相比,i组术后并发症发生率较低。结论:与延迟腹腔镜胆囊切除术相比,早期腹腔镜胆囊切除术可大大缩短胆漏频率和总住院时间。关键词:急性胆囊炎,胆囊切除术,腹腔镜
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引用次数: 0
Prevelence of dermoid cyst in congenital midline craniofacial masses in paediatric population"A case series study in tertiary care hospital. 儿童先天性颅面中线肿块皮样囊肿的发病率:三级医院病例系列研究。
Pub Date : 2022-03-12 DOI: 10.52206/jsmc.2022.12.1.524
Ali Shahjehan, Sajjad ullah, Usman Haqqani
Background: Dermoid cyst is one of the congenital craniofacial masses, most commonly occurring in pediatric population. This study will help us to know the magnitude of dermoid cysts in midline craniofacial masses in children.Objective: To determine the prevalence of dermoid cysts in midline craniofacial masses in pediatric population in tertiary care hospital. Material and Methods: This case series study was conducted at Department of Neurosurgery, Lady Reading Hospital(MTI) Peshawar, Pakistan from March 2016 to February 2019. A total of 52 patients with midline craniofacial masses were studied. After obtaining permission from hospital ethical committee and taking consent from patients included in the study, dermoid cysts in midline craniofacial masses was diagnosed on the basis of histopathology report done in our hospital laboratory. Results: The mean and standard deviation of age was 4.15±3.84years in patients with midline congenital craniofacial masses. Out of 52 patients with midline congenital craniofacial masses, 33(63.5%) patients were from the age group 1-5 years. Out of 52 patients having midline congenital craniofacial masses, 23(44.2%) were females and 29(55.8%) were males. 33 (63.5%) out of 52 patients with midline congenital craniofacial masses resided in urban areas. Out of 52 midline congenital craniofacial masses, 16 (30.8%) were dermoid cysts on histopathological report. Conclusion: Dermoid cyst is a common congenital midline craniofacial mass and is more common in males and urban population. Key words: Midline craniofacial masses, dermoid cyst.
背景:皮样囊肿是一种先天性颅面肿物,最常见于儿童。本研究将帮助我们了解儿童颅面中线肿块皮样囊肿的大小。目的:了解三级医院儿童颅面中线肿块皮样囊肿的发生率。材料和方法:本病例系列研究于2016年3月至2019年2月在巴基斯坦白沙瓦雷丁夫人医院(MTI)神经外科进行。我们对52例颅面中线肿块患者进行了研究。经医院伦理委员会批准并征得纳入研究的患者同意后,根据我院实验室的组织病理学报告诊断颅面中线肿物皮样囊肿。结果:中线先天性颅面肿块患者年龄的平均值和标准差为4.15±3.84岁。52例中线先天性颅面肿块中,年龄在1 ~ 5岁的有33例(63.5%)。52例中线先天性颅面肿块患者中,女性23例(44.2%),男性29例(55.8%)。52例中线先天性颅面肿块患者中有33例(63.5%)居住在城市地区。52例中线先天性颅面肿块中,16例(30.8%)为皮样囊肿。结论:皮样囊肿是一种常见的先天性颅面中线肿块,多见于男性和城市人群。关键词:颅面中线肿块;皮样囊肿;
{"title":"Prevelence of dermoid cyst in congenital midline craniofacial masses in paediatric population\"A case series study in tertiary care hospital.","authors":"Ali Shahjehan, Sajjad ullah, Usman Haqqani","doi":"10.52206/jsmc.2022.12.1.524","DOIUrl":"https://doi.org/10.52206/jsmc.2022.12.1.524","url":null,"abstract":"Background: Dermoid cyst is one of the congenital craniofacial masses, most commonly occurring in pediatric population. This study will help us to know the magnitude of dermoid cysts in midline craniofacial masses in children.Objective: To determine the prevalence of dermoid cysts in midline craniofacial masses in pediatric population in tertiary care hospital. Material and Methods: This case series study was conducted at Department of Neurosurgery, Lady Reading Hospital(MTI) Peshawar, Pakistan from March 2016 to February 2019. A total of 52 patients with midline craniofacial masses were studied. After obtaining permission from hospital ethical committee and taking consent from patients included in the study, dermoid cysts in midline craniofacial masses was diagnosed on the basis of histopathology report done in our hospital laboratory. Results: The mean and standard deviation of age was 4.15±3.84years in patients with midline congenital craniofacial masses. Out of 52 patients with midline congenital craniofacial masses, 33(63.5%) patients were from the age group 1-5 years. Out of 52 patients having midline congenital craniofacial masses, 23(44.2%) were females and 29(55.8%) were males. 33 (63.5%) out of 52 patients with midline congenital craniofacial masses resided in urban areas. Out of 52 midline congenital craniofacial masses, 16 (30.8%) were dermoid cysts on histopathological report. Conclusion: Dermoid cyst is a common congenital midline craniofacial mass and is more common in males and urban population. Key words: Midline craniofacial masses, dermoid cyst.","PeriodicalId":326561,"journal":{"name":"Journal of Saidu Medical College, Swat","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126457337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of Neonatal Plasmodium Vivax Malaria Caused by Exchange Transfusion in a G6PD Deficient Baby G6PD缺陷儿换血致新生儿间日疟原虫疟疾1例
Pub Date : 2022-03-12 DOI: 10.52206/jsmc.2022.12.1.75
M. Ayyaz, Abubakar Saadiq, Zeenat Jehan, Waseem ullah
Abstract: Neonatal malaria is one of the differential diagnoses of sepsis in malaria endemic areas. Neonatal malaria is often ignored as it is considered to be uncommon. Transfusion acquired malaria is among the causes of neonatal malaria, as blood is rarely screened for malarial parasite. Here we present a unique case of neonatal malaria caused by exchange transfusion done for indirect hyperbillirubenemia in a G6PD deficient baby.
摘要:新生儿疟疾是疟疾流行地区败血症的鉴别诊断之一。新生儿疟疾常常被忽视,因为它被认为是不常见的。输血获得性疟疾是新生儿疟疾的原因之一,因为很少对血液进行疟疾寄生虫筛查。在这里,我们提出了一个独特的情况下,新生儿疟疾引起的交换输血为间接高胆红素血症在G6PD缺陷婴儿。
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引用次数: 0
Surgical outcome of Occipitocervical Fixation for Craniocervical Instability 枕颈固定治疗颅颈不稳的手术效果
Pub Date : 2022-03-12 DOI: 10.52206/jsmc.2022.12.1.210
R. Rehman, Muhammad Asad Qureshi, Ahmed Bilal Khalique, Muhammad Waseem Afzal, Muhammad Talha, Syed Junaid Ismail, Ihsanaullah
Background: The occipitocervical junction is a unique area between the cranium and the upper cervical spine. Treating pathologies of this region require a good knowledge and understanding of the anatomy, biomechanics of this region and nature of the disease. Objective: To evaluate the efficacy of Occipitocervical Fixation (OCF) in patients with craniocervical instability in two tertiary care hospitals. Metrial and Methods: This study was conducted at Combined Military Hospital Rawalpindi and Hayatabad Medical Complex, Peshawar from April 2005 to December 2016. All patients with craniocervical instability were included in our study, and those having occipital bone fractures or previously operated patients with same technique were excluded from this study. The patients were compared using lateral static and dynamic X-ray taken before the operation, after the operation, and during last follow-up. The Nurick score was used to assess neurological function pre and postoperatively. Results:  A total of 49 cases with craniocervical instability underwent OCF. The mean age of the patients was 40.5 + 1.2 SD years.  There were 31 male patients and 18 female patients. Majority patients showed improvements in myelopathic symptoms after the operation. The mean preoperative Nurick score was 3.0. At the end of follow-up after surgery, the mean Nurick score was 2.1.  Conclusions: Occipitocervical fixation is a reasonable option to have spinal stability, achieve bone fusion and to get neurological improvement. The procedure can be complicated by certain conditions but these can safely be handled in experience hands.  
背景:枕颈交界处是头盖骨和上颈椎之间的一个独特区域。治疗该区域的病理需要很好的解剖学知识和理解,该区域的生物力学和疾病的性质。目的:评价枕颈固定术(OCF)在两家三级医院治疗颅颈不稳定患者中的疗效。试验与方法:本研究于2005年4月至2016年12月在白沙瓦拉瓦尔品第联合军事医院和哈亚塔巴德医疗中心进行。所有颅颈不稳定的患者都被纳入我们的研究,那些枕骨骨折或以前手术过相同技术的患者被排除在本研究之外。比较术前、术后及末次随访时的侧位静态x线和动态x线。Nurick评分用于评估术前和术后的神经功能。结果:49例颅颈不稳患者行OCF。患者平均年龄40.5 + 1.2 SD年。男性31例,女性18例。多数患者术后脊髓病症状有所改善。术前Nurick评分平均为3.0分。术后随访结束时,平均Nurick评分为2.1。结论:枕颈固定是保持脊柱稳定、实现骨融合和神经系统改善的合理选择。在某些情况下,这个过程可能会很复杂,但这些都可以由有经验的人安全地处理。
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引用次数: 0
Self-Transcendence and Spiritual Well-Being among Stroke Patients 脑卒中患者的自我超越与精神幸福感
Pub Date : 2022-03-12 DOI: 10.52206/jsmc.2022.12.1.628
Muhammad Suliman, Nasreen Ghani, Sohail Muhammad, Pamela G. Reed
Objective: This paper aimed to identify self-transcendence and spiritual well-being among stroke patients and to determine the association between self-transcendence and spiritual well-being among stroke patients. Background: WHO estimated 86% mortality related to stroke world widely occurred in developing countries including, Pakistan. Living a meaningful life after the manifestations of stroke literally demands self-transcendence, which means the reconstruction of life or getting up again with more full potential. Materials and Methods: Analytical cross-sectional study of 210 stroke patients (three months and above inclusion eligibility criteria) were taken from the four rehabilitation centers of SGTH Swat, ATH Abbottabad, LRH and HMC, Peshawar, and responses recorded with validated and reliable questionnaires. Results: The participants’ mean score on the self-transcendence scale was 43.22, and on the spiritual index of well-being mean score were 40.83, respectively. Self-transcendence and spiritual well-being with other demographical variables found statistically significant (p < 0.05) on ANOVA and Post hoc test (Games-Howell). The positive strong correlations between the self-transcendence and spiritual well-being on Pearson correlation (r) were also found statistically significant (r = 0.619, p < 0.000). Conclusion: The results of this study support the theoretical assumptions of Reed’s theory in which during the vulnerability (stroke patients in this study) self-transcendence as an independent variable and protective factor have positive correlations with the outcome and dependant variable, called spiritual well-being. The findings also suggest implications for health care professionals to develop and deliver strategies to enhance vulnerable population self-transcendence for the outcome of spiritual well-being.  Keywords: Self-transcendence, Spiritual well-being, Stroke, Care.
目的:探讨脑卒中患者自我超越与精神幸福感的关系,探讨脑卒中患者自我超越与精神幸福感的关系。背景:世卫组织估计,全世界86%与中风相关的死亡率广泛发生在包括巴基斯坦在内的发展中国家。从字面上讲,在中风的表现之后,要过有意义的生活需要自我超越,这意味着重建生活或以更充分的潜力重新站起来。材料与方法:分析横断面研究210例脑卒中患者(3个月及以上),分别来自sth Swat、ATH Abbottabad、LRH和HMC白沙瓦四个康复中心,并使用有效可靠的问卷记录他们的回答。结果:被试自我超越量表的平均得分为43.22分,幸福感精神指数的平均得分为40.83分。自我超越和精神幸福感与其他人口统计学变量的方差分析和事后检验(Games-Howell)均有统计学意义(p < 0.05)。自我超越与精神幸福感在Pearson相关(r)上呈显著正相关(r = 0.619, p < 0.000)。结论:本研究结果支持Reed理论的理论假设,即脆弱性期间(本研究中的中风患者)自我超越作为自变量和保护因素与结果和因变量精神幸福感呈正相关。研究结果还建议卫生保健专业人员制定和提供战略,以提高弱势群体的自我超越精神福祉的结果。关键词:自我超越,精神幸福,中风,护理。
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引用次数: 0
Effect of Xylocaine 4% Solution on Patient's Anxiety with Nasal Packing After Septoplasty 4%木卡因溶液对鼻中隔成形术后鼻腔填塞患者焦虑的影响
Pub Date : 2022-03-12 DOI: 10.52206/jsmc.2022.12.1.525
Raza Muhammad, Asif Kamal, Fazal-i-Wahid, Aftab Ahmad Tarand, Johar Iqbal, Arshad Abbass
Background: Removal of nasal pack after septoplasty causes pain and anxiety in patients. Xylocaine 4% solution used as topical anesthetic reduces pain and anxiety if infiltrated postoperatively into nasal packing. Objective: To evaluate the effect of xylocaine 4% solution on patient's anxiety infiltrated in to nasal pack after septoplasty. Material and Methods: This prospective case control study conducted at the ENT and Psychiatry departments of Gajju Khan Medical College (GKMC) Swabi from June 2019 to December 2019. A total of 100 patients who underwent septoplasty with bilateral antibiotic ointment soaked nasal packing were randomly divided in to two groups, A & B. Xylocaine 4% solution (5ml in each nostril) was infiltrated into nasal pack in 50 patients in group A while group B including 50 patients were infiltrated with liquid paraffin (5ml in each nostril) fifteen minutes before nasal pack removal.  Results: A total of 100 patients were included with age ranging from 18 to 40 years with a mean age of 25.2 years with male predominance. Hamilton anxiety scale scores in Xylocaine group were11.81+3.47, 15.05+2.99 and 10.6+3.51 at 24 hrs before surgery, 24hrs after surgery and 20 minutes after pack removal while 10.4+4.34, 14.21+4.13 and 12.6+4.54 were in the liquid paraffin group which suggests that anxiety was less in the xylocaine group at 20 minutes after pack removal.  Conclusion:  There was significant reduction in pain and anxiety after infiltration of xylocaine 4% solution into nasal pack post septoplasty. KEY WORDS: Xylocaine, Anxiety, Septoplasty
背景:鼻中隔成形术后鼻塞的去除会引起患者的疼痛和焦虑。4%的木locaine溶液用于局部麻醉,如果术后渗透到鼻腔填充物中,可以减轻疼痛和焦虑。目的:探讨4%木卡因溶液对鼻中隔成形术后患者渗透性焦虑的影响。材料和方法:本前瞻性病例对照研究于2019年6月至2019年12月在斯瓦比Gajju Khan医学院(GKMC)耳鼻喉科和精神科进行。采用双侧抗生素软膏浸泡鼻填充物行鼻中隔成形术的患者共100例,随机分为A、B两组,A组50例,在鼻填充物取出前15分钟向鼻填充物中浸润4% Xylocaine溶液(每个鼻孔5ml), B组50例,在鼻填充物取出前15分钟向鼻填充物中浸润液体石蜡(每个鼻孔5ml)。结果:共纳入100例患者,年龄18 ~ 40岁,平均年龄25.2岁,男性居多。在术前24h、术后24h和脱包后20 min, Xylocaine组汉密尔顿焦虑量表得分分别为11.81+3.47、15.05+2.99和10.6+3.51,而液体石蜡组的汉密尔顿焦虑量表得分分别为10.4+4.34、14.21+4.13和12.6+4.54,说明Xylocaine组在脱包后20 min焦虑程度较轻。结论:鼻中隔成形术后鼻填充物中浸润4%木卡因溶液可明显减轻疼痛和焦虑。关键词:木卡因,焦虑,鼻中隔成形术
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引用次数: 0
A Comparison of Topical Nepafenac with Ketorolac Tromethamine in Maintaining Pupilary Dilatation during Phacoemulsification 外用neafenac与kettorolac tromeamine维持超声乳化术中瞳孔扩张的比较
Pub Date : 2022-03-12 DOI: 10.52206/jsmc.2022.12.1.552
Salah Uddin, Haroon Rashid
Background: The standard surgical procedure for cataract surgery now a days is phacoemulsification with  intraocular lens (IOL) implantation, that gives excellent visual results. Stable and adequate mydriasis is  equired throughout phacoemulsification surgery. Intraoperative pupil Constriction  (miosis) is associated with an increased risk of intraoperative complications especially in  difficult cases and it can result in prolonged surgical time. Objective:  To compare the effectiveness of prophylactic administration of topical ketorolac  tromethamine 0.5% and nepafenac 0.1% on maintaining mydriasis during phacomulsification when instilled for 1 hour (I drop every 15 minutes) before surgery.  Material and Methods: In this study a total of 490 eyes were included (that is 245 eyes in each group), using efficacy of Nepafenac equal to 17.32% and that of ketorolac tromethamine equal to 27.89%,  in terms of loss of pupil  mydriasis from baseline till end of phacoemulsification. Power of test is equal to 80% and level of significance is equal to 5%.   Results: In this study mean age in Group A (nepafenac 0.1%) was 62 year.  while mean age in Group B (ketorolac tromethamine 0.5%) was 64 year with standard deviation  ± 2.87. In Group A (nepafenac 0.1%),(55%) patients were male and (45%) patients were female.  Where as in Group B (ketorolac tromethamine 0.5%), (57%) patients were male and (43%)  patients were female. Conclusion: Our study concludes that Nepafenac 0.1% is more effective than ketorolac tromethamine 0.5% in  maintenance of dilated pupil during phacoemulsification surgery.  KEY WORDS: Nepafenac 0.1%, ketorolac tromethamine 0.5%, dilated pupil,  phacoemulsification surgery
背景:目前白内障手术的标准手术是超声乳化术联合人工晶状体植入术,该手术可获得良好的视力效果。在整个超声乳化手术过程中,需要稳定和充分的泪液。术中瞳孔收缩与术中并发症的风险增加有关,特别是在困难的病例中,它可能导致手术时间延长。目的:比较术前预防性滴注0.5%丙酮酸氨三嗪和0.1%尼帕芬酸1 h(每15分钟滴1次)维持超声乳化过程中滴虫病的效果。材料与方法:本研究共纳入490只眼(每组245只眼),从基线至超声乳化术结束,尼非那克和酮咯酸tromethamine的瞳孔散瞳消失率分别为17.32%和27.89%。检验权值为80%,显著性水平为5%。结果:在本研究中,A组(neafenac 0.1%)平均年龄为62岁。B组(酮咯酸tromethamine 0.5%)平均年龄64岁,标准差±2.87。在A组(neafenac 0.1%)中,男性患者占55%,女性患者占45%。B组(酮咯酸tromethamine 0.5%)中男性占57%,女性占43%。结论:0.1%尼非那酸在超声乳化术中维持瞳孔扩张的效果优于0.5%酮咯酸tromethamine。关键词:0.1%尼非那酸,0.5%酮咯酸,扩大瞳孔,超声乳化手术
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Journal of Saidu Medical College, Swat
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