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Questionnaire Development and Identification of Factors Contributing to Non-Prescription Antibiotic Selling Behavior in Surabaya Community Setting 泗水社区环境中非处方抗生素销售行为的问卷调查与因素识别
Pub Date : 2018-10-31 DOI: 10.22146/JMPF.36366
Dewi Paskalia Andi Djawaria, A. P. Setiadi, E. Setiawan
The selling practice of antibiotics without prescription is one of serious problems in the global health sector, especially in the developing countries. Nevertheless, the significant driver of such pratices had never been identified yet. The aim of this study was to identify the contributing factors of the selling practice of antibiotics without prescription in the drug stores (apotek). The identification was conducted using a new developed questionnaire. The contributing factors of such practices, found in the literature, were used to develop the questionnaire. The face and content validity were conducted using expert opinion, while the construct validity was conducted using the Spearman correlation test. The reliability of the questionnaire was identified using Cronbach’s Alpha test. The dominant factors of the selling practice of antibiotics without prescription was identified by using descriptive analysis and the factor analysis methods. The final questionnaire consisted of 40 questions and the value of the Cronbach’s Alpha and the calculated R were 0.955 and 0.368-0.867, consecutively. There were 91 workers of apotek in Surabaya who were involved in the contributing factors identification process. Findings of the factor analysis emphasized that the most dominant factor was the attitude of workers that allowed the selling practice of antibiotics without prescription (28.3%). The financial issue was found as the second most dominant factors causing the selling practice of antibiotics without prescription (8.66%). Owing to these identified factors, there is a need to make a regulation with a strict punishment in order to prevent the habit of selling and purchasing the antibiotics without prescription in the apotek in Surabaya.
无处方销售抗生素是全球卫生部门的严重问题之一,尤其是在发展中国家。然而,这种做法的主要驱动因素尚未确定。本研究的目的是确定药店无处方销售抗生素的影响因素(apotek)。鉴定是使用新开发的问卷进行的。在文献中发现的这种做法的促成因素被用于制定问卷。面孔和内容的有效性采用专家意见进行,而结构的有效性则采用Spearman相关检验进行。使用Cronbach的Alpha检验来确定问卷的可靠性。采用描述性分析和因子分析方法,确定了无处方抗生素销售行为的主导因素。最终问卷由40个问题组成,Cronbachα值和计算出的R值分别为0.955和0.368-0.867。泗水apotek有91名工人参与了因素识别过程。因素分析的结果强调,最主要的因素是工人允许在没有处方的情况下销售抗生素的态度(28.3%)。财务问题被认为是导致无处方销售抗生素的第二主要因素(8.66%),有必要制定一项严格惩罚的法规,以防止在泗水的apotek无处方销售和购买抗生素的习惯。
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引用次数: 1
Evaluating Inhaler Use Technique among Asthma and COPD Patients at a Primary Health Care Unit: A Pilot Study in Selangor Malaysia 在初级保健室评估哮喘和COPD患者的吸入器使用技术:马来西亚雪兰莪州的一项试点研究
Pub Date : 2018-07-31 DOI: 10.22146/jmpf.33829
Z. Zazuli, K. Ramasamy, I. Adnyana
Inhaler is the most preferable device to deliver medication in order to treat asthma and Chronic Obstructive Pulmonary Disease (COPD). Incorrect usage of inhaler influences the clinical effectiveness of the delivered drug. A pilot study was conducted to determine the appropriateness of inhaler handling technique among asthma and COPD patients. As many as 92 subjects whom diagnosed with asthma and COPD, aged between 18 to 64 years old were observed in this cross-sectional study. Consenting subjects on inhaler, who attended medical out patients clinic at a primary health care unit in Selangor, Malaysia were asked to demonstrate on how they use the inhaler while an inhaler administration checklist were used to assess each patients inhaler technique. Data was analysed using descriptive statistical methods. Of total 92 patients, a total of 155 devices were used. Only 4 out of 92 patients correctly handles the device (4.3%). In average, a patient made approximately >4 mistakes during pMDI inhalation and >2 mistakes during DPI inhalation. The most common mistake found among pMDI, Turbuhaler and Accuhaler users were unable to hold the breath for approximately 5 seconds in which comprise of ≥80% patients. In conclusion, majority of asthma and COPD patients use their inhaler inaccurately. Patients prescribed by inhalation medications should have routine assessment of their inhaler technique at every visit and corrected if found to be poor.
吸入器是治疗哮喘和慢性阻塞性肺疾病(COPD)最理想的药物输送设备。不正确使用吸入器会影响给药的临床效果。进行了一项初步研究,以确定哮喘和COPD患者吸入器处理技术的适宜性。在这项横断面研究中,多达92名被诊断患有哮喘和慢性阻塞性肺病的受试者,年龄在18至64岁之间。在马来西亚雪兰莪州的一个初级保健单位的医疗门诊部,同意使用吸入器的受试者被要求展示他们如何使用吸入器,同时使用吸入器管理清单来评估每位患者的吸入器技术。数据分析采用描述性统计方法。在92例患者中,共使用了155个器械。92名患者中只有4人正确使用器械(4.3%)。平均每名患者吸入pMDI时出现约bbb40次错误,吸入DPI时出现约>2次错误。pMDI、Turbuhaler和Accuhaler使用者中最常见的错误是无法屏住呼吸约5秒,其中包括≥80%的患者。总之,大多数哮喘和慢性阻塞性肺病患者使用吸入器不准确。服用吸入性药物的患者应在每次就诊时对其吸入器技术进行常规评估,如果发现效果不佳,应予以纠正。
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引用次数: 2
Cost Effectiveness Analysis of Crystalloid and Crystaloid-Colloid Combination on Dengue Fever without Shok in Bhakti Asih General Hospital Tangerang 类晶体和类晶体胶体联合治疗唐格朗巴克提阿西综合医院无Shok登革热的成本-效果分析
Pub Date : 2018-07-31 DOI: 10.22146/JMPF.33367
Suratni Suratni, Y. Anggriani, Agusdini Banun
Dengue fever is an infectious disease caused by virus transmitted through Aedes aegypty. The high incidence dengue fever can lead to increased healthcare costs. This study was conducted to analyze the effectiveness and direct cost of medical patients dengue fever without shock use fluid therapy by comparing crystalloid and crystalloid colloid combination. The subjects were 171 patients divided into two groups: 106 patients with crystalloid and 65 patients with crystalloid colloid combination. Assessed of effectiveness treatment and the mean medical costs. The results showed reviewed from hematocrit value no difference (p>0.05) in both study groups. The mean total cost of treatment for crystalloid Rp 4.005.223, the crystalloid colloid combination Rp 5.525.407. The highest cost of drug costs was 31.75% of the total cost crystalloid, 40.9% of the total cost crystalloid colloid combination. There was a significant difference between mean cost and two study groups (p0.05) with effectiveness treatment. Conclusion crystalloid have the same effectiveness as crystalloid colloid combination fluids at lower costs.
登革热是一种由通过埃及伊蚊传播的病毒引起的传染病。登革热的高发病率可导致医疗费用增加。本研究通过比较晶体与晶体胶体联合治疗对非休克登革热患者的治疗效果和直接成本进行分析。研究对象为171例患者,分为两组:晶体-胶体联合组106例,晶体-胶体联合组65例。评估治疗效果及平均医疗费用。结果显示,两组患者的红细胞压积值无差异(p < 0.05)。平均总治疗费用为结晶法Rp 4.005.223,结晶法胶体组合Rp 5.525.407。药品成本最高的是晶体总成本的31.75%,晶体-胶体组合总成本的40.9%。经有效治疗后,两组患者的平均成本差异有统计学意义(p0.05)。结论结晶液与结晶-胶体复合液具有相同的疗效,且成本较低。
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引用次数: 2
Factors Affecting Non-Adherence to Secondary Stroke Prevention Therapy in Ischemic Stroke Patients 影响缺血性脑卒中患者不坚持二级卒中预防治疗的因素
Pub Date : 2018-07-31 DOI: 10.22146/jmpf.34434
Z. Cholisoh, Hidayah Karuniawati, Tanti Azizah, Zaenab Zaenab, Laila Nur Hekmah
Stroke is cardiovascular disease that causes the world's highest disability and is the most prevalence disease after heart disease and cancer. Stroke is caused by circulatory disorders with 80% of the sufferers are diagnosed with ischemic stroke and 20% of them are diagnosed with hemorrhagic stroke. Patients who survive from the first stroke have high risk to have recurrent stroke. American Heart Association/American Stroke Association and Perhimpunan Dokter Spesialis Syaraf Indonesia recommend secondary stroke prevention therapy including antiplatelet/anticoagulant, antihypertensive agents, and antidislipidemia to minimalize the risk of recurrent stroke. Secondary stroke prevention therapy is only the first step. Patients need to be adhere to those therapies. The non-adherence will increase the risk of recurrent stroke. The study aimed to determine factors which causing the non-adherence to secondary prevention therapy in patients with ischemic stroke. This was a case control study with concecutive sampling method by interviewing patients who met the inclusion criterias i.e., had been diagnosed and were inpatients due to ischemic stroke, but in the time of interview patients were outpatients, patients were able to communicate and agree to participate in the study.Data was analized by bivariate / chi square test and multivariate logistic regression test. During the study period, 184 respondents met the inclusion criterias. Factors affecting non-adherence in the use of secondary prevention therapy were No one reminded to take medicine p = 0.03; OR 4.51, denial of the disease p = 0,036 OR 214, and tired of taking medicine p = 0,045 OR 1,97.
中风是导致世界上残疾率最高的心血管疾病,也是仅次于心脏病和癌症的最常见疾病。中风是由循环系统疾病引起的,80%的患者被诊断为缺血性中风,20%的患者被确诊为出血性中风。从第一次中风中幸存下来的患者复发中风的风险很高。美国心脏协会/美国中风协会和印度尼西亚Perhimpunan Dokter Spesialis Syaraf建议进行二次中风预防治疗,包括抗血小板/抗凝剂、抗高血压药物和抗脂血症,以将复发性中风的风险降至最低。二级脑卒中预防治疗只是第一步。患者需要坚持这些疗法。不坚持会增加复发性中风的风险。本研究旨在确定缺血性脑卒中患者不坚持二级预防治疗的因素。这是一项采用连续抽样方法的病例对照研究,通过访谈符合纳入标准的患者,即已被诊断为缺血性中风住院患者,但在访谈时,患者是门诊患者,患者能够沟通并同意参与研究。数据采用双变量/卡方检验和多变量逻辑回归检验进行分析。在研究期间,184名受访者符合纳入标准。影响二级预防治疗不依从性的因素是:没有人被提醒服药p=0.03;OR 4.51,否认疾病p=0036 OR 214,厌倦服药p=0045 OR 1,97。
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引用次数: 0
Description of Professional Fee for Pharmacist in Sleman Sleman药剂师专业费用说明
Pub Date : 2018-07-31 DOI: 10.22146/JMPF.34062
Hardika Aditama, A. Saputri, D. Fadhilah, K. Mayningrum, A. Sawitri, W. A. Pratiwi, I. N. Pristhifani
Pharmacist is a profession whose existence is needed by community. However, within the community of pharmacy itself, the presence of pharmacist is quite alarming. One of the causes of low pharmacist who desire to practice in the community of pharmacy is the low level of professional fee offered. This study aimed to describe professional fee received by pharmacist and the workload of pharmacist in Sleman. This study was a descriptive non-experimental that was conducted in Sleman in August 2017. Population of this study was a pharmacist who practiced in community of pharmacy in Sleman. Total of 170 respondents from 128 pharmacies were involved in this research. However, 6 questionnaires cannot be analyzed because it is not completely filled. The highest amount of professional fee is between Rp 2.000.000-Rp 3.000.000. Almost all respondents (78%) stated the amount of professional fee that was received was not as expected. The workload of pharmacists is not so heavy and most of the patient are self medication. Pharmacists at the community of pharmacy should be able to show a better work performace, which is shown by increasing pharmacy revenues to get a better rewards.
药剂师是一个社会需要生存的职业。然而,在药学界,药剂师的存在是相当令人担忧的。药剂师在药学界执业意愿低的原因之一是提供的专业费用水平低。本研究旨在描述Sleman药剂师收取的专业费用和药剂师的工作量。这项研究是一项描述性的非实验性研究,于2017年8月在Sleman进行。这项研究的对象是一名在Sleman药房社区执业的药剂师。共有来自128家药店的170名受访者参与了这项研究。但是,有6份调查问卷由于填写不全而无法进行分析。专业费用的最高金额在2.000.000卢比至3.000.000卢比之间。几乎所有受访者(78%)都表示,收到的专业费用金额没有达到预期。药剂师的工作量没有那么大,大多数患者都是自行用药。药房社区的药剂师应该能够表现出更好的工作表现,这表现为增加药房收入以获得更好的奖励。
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引用次数: 0
Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta Sleman-Yogyakarta社区10年心血管疾病风险评估的五种方法比较
Pub Date : 2018-07-31 DOI: 10.22146/JMPF.34469
Clarentia Dwivani, H. Herlina, Karina Harijadi, Budianto Budianto, Rita Suhadi
Cardiovascular disease is the highest cause of death with total of 17.5 million deaths in the world. Nowadays there have beenexists many methods to calculate the risk of cardiovascular disease within the next 10 years, 5 of them are Framingham Risk Score (FRS) BMI and Cholesterol, Pooled Cohort Equations (PCE), CV Risk Calculator, and Systematic Coronary Risk Evaluation (SCORE). The aim of this study waiss to compare the 5 methods of 10-year risk of cardiovascular disease based on mean values, risk categories, and statin recommendation. This observational analytic study was done with cross-sectional design. There were 169 respondents in Sleman, Yogyakarta who participated to this study. Normality of risk measurement data was performed using Kolmogorov-Smirnov test and comparative test was performed using Repeated ANOVA. Both proportion of risk categorization and statin therapy was calculated using the Marginal Homogeneity test. The average risk of  FRS (BMI and Cholesterol), PCE, CV Risk Calculator, and SCORE were 14,6±11,7% (medium risk), 13,3±11,3% (medium risk), 6,8±6,4% (medium risk), 6,8±6,4% (medium risk), and 2,6±3,5% (medium risk).  There were significant differences from the comparison between among methods on mean values and risk categories (p <0.01), except on PCE with FRS BMI (p=0.11) and PCE with CVRiskcalculator (p = 1.00). Comparison of statin therapy recommendation among FRS Cholesterol with PCE, FRS Cholesterol with SCORE, and PCE with FRS BMI methods showed significant differences (p <0.01), whereas FRS Cholesterol with FRS BMI and PCE with SCORE were not significantly different (p = 0,06 and p = 0,05).
心血管疾病是世界上死亡人数最多的疾病,共有1750万人死亡。目前已经有许多方法来计算未来10年内患心血管疾病的风险,其中5种是Framingham风险评分(FRS)、BMI和胆固醇、汇集队列方程(PCE)、CV风险计算器和系统冠状动脉风险评估(Score)。本研究的目的是比较基于平均值、风险类别和他汀类药物推荐的5种心血管疾病10年风险方法。这项观察性分析研究采用横断面设计。日惹Sleman有169名受访者参与了这项研究。风险测量数据的正态性使用Kolmogorov-Smirnov检验进行,比较检验使用重复方差分析进行。风险分类和他汀类药物治疗的比例均采用边际同质性检验进行计算。FRS(BMI和胆固醇)、PCE、CV风险计算器和SCORE的平均风险分别为14,6±11,7%(中等风险)、13,3±11,3%(中等危险)、6,8±6.4%(中度危险)、6.8,6.4%(中度风险)和2,6±3,5%(中危险)。除PCE与FRS BMI(p=0.11)和PCE与CVRiskcalculator(p=1.00)外,不同方法之间的平均值和风险类别比较有显著差异(p<0.01),而FRS胆固醇与FRS BMI和PCE与SCORE没有显著差异(p=0,06和p=0,05)。
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Jurnal Manajemen dan Pelayanan Farmasi
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