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Profil Kontrol Glikemik Antidiabetik pada Pasien DM Tipe 2 dengan Sirosis Hati 2型DM肝硬化患者血糖控制概要
Pub Date : 2022-03-31 DOI: 10.22146/jmpf.68075
Emy Oktaviani, Lusi Indriani, Haryanti Wulandari
Diabetes mellitus (DM) is a metabolic syndrome with multi-etiology characterized by chronic hyperglycemia. DM can cause a variety of complications, one of which is impaired liver function. The use of antidiabetics needs to get more attention because most antidiabetics are metabolized in the heart. This study aims to determine the control of antidiabetic glycemic, the relationship of antidiabetic types with effectiveness, as well as factors related to glycemic control in type 2 DM patients with liver cirrhosis.  This research was conducted in June-July at Fatmawati Central General Hospital with cross sectional design and data retrieval period of 2014-2019 conducted retrospectively. The observation parameters of glucose control in this study were current blood sugar (GDS). Of the 106 patients who met the inclusion criteria, it was seen that the use of insulin aspart single in 34 patients showed good glycemic control followed by the use of combination insulin glargine-aspart in 25 patients. The results of the Chi-square analysis showed that there was no significant relationship between the type of antidiabetic on glycemic control (p-value = 0,159). However, the results of the Chi-square test showed that there was a significant relationship between the severity of liver cirrhosis and glycemic control (p-value=0,021) and gender was another factor that also showed a significant relationship to glycemic control (p-value=0,042). The use of insulin aspart alone or in combination with insulin glargine is the best in controlling blood sugar levels while in T2DM patients with liver cirrhosis based on this study.
糖尿病(DM)是一种以慢性高血糖为特征的多病因代谢综合征。糖尿病可引起多种并发症,其中之一是肝功能受损。抗糖尿病药物的使用需要得到更多的关注,因为大多数抗糖尿病药物是在心脏代谢的。本研究旨在了解2型糖尿病合并肝硬化患者的降糖血糖控制情况、降糖类型与效果的关系以及降糖控制的相关因素。本研究于6 - 7月在法塔玛瓦蒂中央总医院进行,采用回顾性横断面设计,数据检索期为2014-2019年。本研究血糖控制的观察参数为当前血糖(GDS)。在106例符合纳入标准的患者中,34例患者单独使用天冬氨酸胰岛素血糖控制良好,25例患者联合使用甘精胰岛素-天冬氨酸胰岛素血糖控制良好。卡方分析结果显示,抗糖尿病类型与血糖控制之间无显著关系(p值= 0.159)。然而,卡方检验结果显示,肝硬化严重程度与血糖控制之间存在显著相关性(p值= 0.021),性别是另一个与血糖控制也存在显著相关性的因素(p值= 0.042)。根据本研究,在T2DM合并肝硬化患者中,单用间天冬氨酸胰岛素或联合使用甘精胰岛素控制血糖水平效果最好。
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引用次数: 0
Efektivitas Pengobatan pada Pasien Penyakit Paru Obstruksi Kronis (PPOK) di Rumah Sakit Wilayah Yogyakarta 日惹医院慢性阻塞性肺病患者的治疗有效
Pub Date : 2021-12-31 DOI: 10.22146/jmpf.56418
Chynthia Pradiftha Sari, S. Hanifah., R. Rosdiana, Y. Anisa
Chronic Obstructive Pulmonary Disease (COPD) is a complex respiratory disorder that requires multiple approaches to assess treatment response, no specific therapy can stop the progression of disease cure. This study aimed to measure the response of COPD treatment in outpatients at Hospitals in Yogyakarta. The study was designed descriptive observational cross-sectional involved  COPD outpatients in July 2018 - June 2019 (N = 156). Inclusion criteria the subjects: age> 40 years, without other respiratory diseases (asthma, lung cancer), took theophylline for at least the last one month, complete the CAT questionnaire, and sign an informed consent. Data collected were characteristics of respondents, treatment profile (exacerbation, maintenance), and response therapy data. Evaluation of treatment response was measured using the COPD Assessment Test (CAT) questionnaire and classified the response into effective, quite effective, and not effective. These data were then presented in form of percentage distribution. The results showed that an exacerbation study with single bronchodilator 39.10%, and a combination of bronchodilator with other bronchodilators 60.90%, most LABA-ICS / LAMA rescue therapies (48.72%). Results of evaluation the use of LABA-ICS / LAMA / Methylxanthine (18.59%), LABA-ICS / LAMA / Methylxanthine/ Mucolytic (11.54%), LABA-ICS / LAMA / SABA / Methylxanthine / Mucolytic (9.62%) )) gave a fairly effective treatment response (CAT score ≥10-19) 50.64%, effective (CAT score <10) 47.43%, ineffective (CAT score ≥20) 1.93%.
慢性阻塞性肺疾病(COPD)是一种复杂的呼吸系统疾病,需要多种方法来评估治疗反应,没有特定的治疗方法可以阻止疾病的治愈进展。本研究旨在测量日惹医院门诊患者COPD治疗的反应。该研究设计为描述性观察横断面,涉及2018年7月至2019年6月的COPD门诊患者(N = 156)。纳入标准:受试者年龄在40岁至40岁之间,无其他呼吸系统疾病(哮喘、肺癌),服用茶碱至少一个月,完成CAT问卷,并签署知情同意书。收集的数据包括受访者的特征、治疗概况(恶化、维持)和反应性治疗数据。使用COPD评估测试(CAT)问卷对治疗反应进行评估,并将疗效分为有效、相当有效和无效。然后将这些数据以百分比分布的形式呈现。结果显示,在急性加重研究中,单用支气管扩张剂占39.10%,联用其他支气管扩张剂占60.90%,LABA-ICS / LAMA抢救治疗占48.72%。评价结果显示,使用LABA-ICS / LAMA /甲黄嘌呤(18.59%)、LABA-ICS / LAMA /甲黄嘌呤/ Mucolytic(11.54%)、LABA-ICS / LAMA / SABA /甲黄嘌呤/ Mucolytic(9.62%))的治疗效果相当有效(CAT评分≥10-19)50.64%,有效(CAT评分<10)47.43%,无效(CAT评分≥20)1.93%。
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引用次数: 2
Analisis Mutu Pengelolaan Obat di Puskesmas Kota Tegal 家乡城市药品管理的互动分析
Pub Date : 2021-12-31 DOI: 10.22146/jmpf.69095
Cholilah Cholilah, Tri Wijayanti, S. Satibi
Primary health centers is a facility that organizes health efforts at the first level to achieve health degrees, but in its implementation is still constrained in realizing standard pharmaceutical services. The purpose of the research is to find out the quality of drug management in Tegal City primary Health Center. This study is a non-experimental descriptive study. The study was conducted throughout the primary health center in Tegal City. Data collection is prospective and retrospective by tracing documents to obtain secondary data and direct observations, interviews of pharmaceutical personnel, heads of primary health centers, and heads of the pharmaceutical section to obtain primary data. The next drug management indicator is done descriptive data analysis by calculating the value of the indicator with the formula then compared to the standard and inter primary health care. Indicators of drug management used 28 and those that meet standard 10. Indicator results include conformity of items with disease patterns 76.39%, planning accuracy 321.10%, the accuracy of the number of requests 169.84%, the storage of narcotics 72.92%, the storage of drugs without contamination 98.97%, the storage of high alert drugs 68.15%, the storage of LASA drugs 87.5%, ITOR 1.87 times /year, the availability of drugs 36.08 months, drug items less than 14.01%, safe drug items 37.94%, excess stock items 41.76%, non-prescribed drugs 4.59% and drug value ED 3.85%. These results show that drug management indicators in Tegal City primary health centers have not been efficient and need improvements ranging from the planning stage to control. Indicators that still need improvement include ITOR and all indicators of drug availability. Things that need to be done to improve indicators that have not been efficient include increasing the number and quality of pharmaceutical human resources in primary health centers, increasing supervision of drug use and control, building communication, and a good organizing culture in primary health centers.
初级卫生中心是一个组织一级卫生工作以获得健康学位的机构,但在实施过程中,在实现标准药物服务方面仍然受到限制。本研究的目的是了解特加尔市初级卫生中心的药品管理质量。本研究为非实验性描述性研究。这项研究在特加尔市的初级卫生中心进行。数据收集是前瞻性和回顾性的,通过追踪文件获得二级数据和直接观察,采访制药人员、初级卫生中心负责人和制药部门负责人获得初级数据。下一个药物管理指标是通过用公式计算指标的值来进行描述性数据分析,然后与标准和初级保健进行比较。药物管理指标使用了28项,符合标准的指标使用了10项。指标结果包括项目符合疾病模式76.39%,计划准确率321.10%,请求数量准确率169.84%,毒品储存72.92%,无污染药品储存98.97%,高警戒药品储存68.15%,LASA药品储存87.5%,ITOR 1.87次/年,药品可得性36.08个月,药品项目低于14.01%,安全药品项目37.94%,超额库存项目41.76%,非处方药4.59%,药品价值ED 3.85%。仍需改进的指标包括ITOR和所有药物供应指标。需要做的事情包括提高初级卫生中心药物人力资源的数量和质量,加强对药物使用和控制的监督,建立沟通,以及在初级卫生中心建立良好的组织文化。
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引用次数: 2
Analisis Korelasi Gula Darah Puasa, HbA1c, dan Karakteristik Partisipan 潜在血鸥相关性、HbA1c和参与特征的分析
Pub Date : 2021-12-31 DOI: 10.22146/jmpf.62292
N. Hasanah, Zullies Ikawati, Apt.
Hemoglobin A1c (HbA1c) measurement is recommended as the gold standard in long-term blood sugar monitoring the diabetes patients because the fasting blood sugar (FBG) pattern alone cannot provide accurate information regarding the blood sugar variability true picture in type 2 Diabetes mellitus (T2DM) patients. However, many patients have limited access to HbA1c testing for financial reasons. It is necessary to know the relationship between HbA1c and GDP, and the factors that influence it, especially the research participant characteristics. This analytic observational study with a cross-sectional design involved 100 participants from T2DM patients in the hospital, outpatient clinics, and communities in Yogyakarta Province from January-May 2020. The HbA1c and FPG measurement was carried out using capillary blood samples by the research team. Characteristic data were obtained through direct interviews with participants, then analyzed using SPSS version 25 for windows, using the chi-square, Kolmogorov-Smirnov, and Spearman's rho test. The results showed that FPG was significantly positively correlated with HbA1c with moderate correlation criteria (r=0.74, P-value<0.0001). FPG showed a significant negative correlation to the glucometer ownership variable (r=-0.22, P-value= 0.04), and was independent of other parameters. Meanwhile, HbA1c significantly negatively correlated with age (r=-0.26, P-value=0.01), education level (r=-0.22, P-value=0.04), comorbidity (r=-0, 24, P-value=0.02), routine drug consumption (r=-0.29, P-value=0.01) and the ownership of glucometer (r=-0.26, P-value=0.01), but independent of gender, smoking status, daily menu, and physical exercise. It can be concluded that both GDP and HbA1c can be used as a reference for assessing glycemic status.
糖化血红蛋白(HbA1c)测量被推荐作为长期血糖监测糖尿病患者的金标准,因为单独的空腹血糖(FBG)模式不能提供关于2型糖尿病(T2DM)患者血糖变异性的准确信息。然而,由于经济原因,许多患者无法获得HbA1c检测。有必要了解HbA1c与GDP的关系,以及影响因素,特别是研究参与者的特征。这项横断面设计的分析性观察研究纳入了2020年1月至5月日惹省医院、门诊和社区的100名T2DM患者。HbA1c和FPG测量由课题组使用毛细血管血液样本进行。通过与参与者的直接访谈获得特征数据,然后使用SPSS version 25 for windows,使用卡方检验,Kolmogorov-Smirnov检验和Spearman's rho检验进行分析。结果显示,FPG与HbA1c呈正相关,呈中度相关标准(r=0.74, p值<0.0001)。FPG与血糖仪所有权变量呈显著负相关(r=-0.22, p值= 0.04),与其他参数无关。同时,HbA1c与年龄(r=-0.26, p值=0.01)、文化程度(r=-0.22, p值=0.04)、合病(r=- 0,24, p值=0.02)、常规用药(r=-0.29, p值=0.01)、是否拥有血糖仪(r=-0.26, p值=0.01)呈显著负相关,与性别、吸烟状况、日常菜单、体育锻炼无关。由此可见,GDP和HbA1c均可作为评估血糖状态的参考指标。
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引用次数: 0
Parental Use of Internet to Navigate Online Health Information for Their Children: An Indonesian Context 父母使用互联网为他们的孩子浏览在线健康信息:印度尼西亚的背景
Pub Date : 2021-12-31 DOI: 10.22146/jmpf.64781
H. Ramadaniati, N. Andayani, Zata Yumni Azizah
Internet-resourced health information becomes increasingly common amongst parents before doctor consultation. This study aimed to explore the demographics of online health information-seeking parents and the type of information on children’s healthcare needs and the relationship between the demographics and the online sources. A cross-sectional study was conducted at two Primary Health Centers (PHC) in Jakarta. The respondents were parents of acutely ill children seeking online health information before visiting PHC. A validated questionnaire was distributed to the respondents. Parents’ demographics and type of information were analyzed descriptively. The relationship between the demographics and the information source was tested using the Chi-Square test. 478 respondents were participating in this study where most of the respondents were mothers (75.1%), aged 26-35 years (57.7%), and had 1-2 children (70.7%). Most of them were high-school graduates (64.9%) and unemployed (49.6%). Google (61.5%) was predominantly the most frequently used digital media, followed by websites run by doctors (21.9%). The most sought information included illness causes, transmission probability, treatment, and medicines’ side effects. There was no significant relationship between any demographics and the types of online sources. In conclusion, illness-related basic information is used by most parents to be informed before seeing doctors. The link between parents’ characteristics and the selection of digital media could not be determined.
在医生咨询之前,父母在互联网上获取健康信息变得越来越普遍。本研究旨在探讨网路健康资讯搜寻父母的人口统计资料、儿童健康资讯需求的类型,以及人口统计资料与网路资讯来源的关系。在雅加达的两个初级保健中心(PHC)进行了横断面研究。受访者是在访问初级保健医院之前在网上寻求健康信息的重症儿童的父母。向受访者分发了一份有效的问卷。对家长的人口统计信息和信息类型进行描述性分析。人口统计学与信息源之间的关系采用卡方检验。共有478名受访者参与本研究,其中以母亲(75.1%)居多,年龄在26-35岁(57.7%),有1-2个孩子(70.7%)。大部分是高中毕业生(64.9%)和无业人员(49.6%)。b谷歌(61.5%)是最常使用的数字媒体,其次是医生运营的网站(21.9%)。最受关注的信息包括致病原因、传播概率、治疗方法和药物副作用。任何人口统计数据和在线资源类型之间没有显著的关系。综上所述,大多数家长在看医生前都会了解与疾病相关的基本信息。父母的性格特征与数字媒体的选择之间的联系无法确定。
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引用次数: 0
Kepatuhan terhadap Protokol Kesehatan oleh Tenaga Teknis Kefarmasian di Apotek 遵守药房的制药技术协议
Pub Date : 2021-12-31 DOI: 10.22146/jmpf.70373
Fathul Muin, Anna Wahyuni Widayanti, Yayi Suryo Prabandari
Pharmacy technician as health workers in pharmacies have high risk of transmitting the COVID-19 virus. They often have direct contact to public or COVID-19 patients who come to pharmacies. This study aimed to determine the compliance level of pharmacy technician to the COVID-19 health protocols and its correlations to the level of knowledge, organizational-environment and self-efficacy. This study was designed descriptive correlational used self-administered questionnaire to collect data with cross sectional study. The participants were selected with simple random sampling among pharmacy technician who worked in community pharmacies in Sleman. A total of 98 pharmacy technician were participated in this study. The compliance levels were divided into low, medium and high. Most participants were in medium level of compliance (61.2%), followed by high level (35.7%) and only 3.1% participants in low level. Data analysis was carried out by cross-sectional and statistical test with SPSS by comparing the three factors to the level of compliance. Statistical tests on organizational-environmental factors and self-efficacy showed a significance value (p<0.05) with a Pearson Correlation value of 0.393 and 0.350. The level of knowledge showed not significance value (p>0.05) with a Pearson Correlation value of 0.152. There was a correlation between organizational-environmental factors and self-efficacy with the the compliance level of pharmacist assistants to the COVID-19 health protocols. While the level of knowledge showed results that there is no correlation.
药学技术人员作为药店的卫生工作者,具有传播COVID-19病毒的高风险。他们经常与来到药房的公众或COVID-19患者直接接触。本研究旨在了解药学技术人员对COVID-19健康方案的遵守程度及其与知识水平、组织环境水平和自我效能感的相关性。本研究采用描述性相关设计,采用自填问卷收集资料,采用横断面研究。研究对象采用简单随机抽样的方法,选取在Sleman市社区药房工作的药学技术人员。共98名药学技术人员参与了本研究。达标程度分为低、中、高三个等级。大多数受试者为中等依从性(61.2%),其次为高依从性(35.7%),低依从性仅占3.1%。将三个因素与依从性水平进行比较,采用SPSS进行横断面检验和统计检验。组织环境因素与自我效能感的统计检验显示有显著性值(p0.05), Pearson相关值为0.152。组织环境因素、自我效能感与药师助理对COVID-19健康方案的遵守程度存在相关性。而知识水平显示的结果则没有相关性。
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引用次数: 1
Evaluasi Pengelolaan Obat dan Bahan Medis Habis Pakai di Puskesmas Kota Kupang serta Strategi Pengembangannya 库邦市医疗中心的药物和医疗管理评价以及开发战略已经过时
Pub Date : 2021-12-31 DOI: 10.22146/jmpf.61365
Novi Winda Lutsina, Arman Rifat Lette
The management of drugs and disposable medical supplies in healthcare units greatly affects the quality of healthcare services. However, the management is still not carried out optimally because it is not up to the standard. The Hanlon method is a basic priority rating system (Brief Priority Rating Scale, BPRS) which is used to compare health problems with relative and objective to identify factors that must be considered in determining a priority. This study aimed to describe and measure the efficiency of drugs and disposable medical supplies management in Healthcare Centers in Kupang City by using efficiency indicators and to develop the strategy using the Hanlon method. The design of this research is a descriptive quantitative-qualitative combination using retrospective and concurrent data. The sampling technique used was a total sampling of 11 Healthcare Centers in Kupang City, while the object of the study was the management of drugs and disposable medical supplies which were assessed using efficiency indicators. The results of research on the management of medicines and consumable medical materials at 11 Healthcare Centers in Kupang City have not been carried out efficiently because not all indicator values reached the standard, namely the suitability of drug items with DOEN and FORNAS, conformity of items received, the accuracy of planning, items expired or damaged, items that were not prescribed for 3 months, the level of availability of the drug, the percentage of drugs with generic names, use of antibiotics in patients with non-specific diarrhea and the average item per prescription sheet. Therefore it can be concluded that the management of drugs and disposable medical supplies in 11 Healthcare Centers in Kupang City using indicators at the selection, procurement, distribution, and use stages are not yet according to standards and the proposed improvements are proposed as a management development strategy, namely optimizing planning according to the needs of the health center, monitoring stock. and expiration date and conduct regular learning and growth of all human resources.
卫生保健单位药品和一次性医疗用品的管理,极大地影响着卫生保健服务的质量。然而,由于管理不达标,仍然没有得到最优的实施。汉龙方法是一种基本的优先级评定系统(简要优先级评定量表,BPRS),用于将健康问题与相对客观的问题进行比较,以确定在确定优先级时必须考虑的因素。本研究旨在以效率指标描述及衡量姑邦市医疗中心药品及一次性医疗用品的管理效率,并以汉龙方法制定策略。本研究的设计是描述性定量和定性结合使用回顾性和并发数据。采用的抽样技术是对古邦市11个医疗保健中心的总抽样,而研究对象是药物和一次性医疗用品的管理,并使用效率指标进行评估。对库邦市11个保健中心药品和医疗耗材管理的研究结果没有得到有效执行,因为并非所有指标值都达到标准,即DOEN和FORNAS药品的适用性、收到的药品的符合性、计划的准确性、过期或损坏的药品、3个月内未开处方的药品、药品的可获得性水平、具有通用名称的药品百分比、非特异性腹泻患者抗生素使用情况及每张处方单的平均用药项目。由此得出,库邦市11家医疗中心的药品和一次性医疗用品在选择、采购、配送和使用阶段的指标管理尚不规范,提出改进建议作为一种管理发展策略,即根据医疗中心的需求优化规划,监控库存。并定期对所有人力资源进行学习和成长。
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引用次数: 1
Pemanfaatan Geospasial Melalui Health and Demographic Surveillance System (HDSS) pada Pasien Tuberkulosis dalam Manajemen Obat 通过健康和人口监测系统(HDSS)在结核病患者药物管理中的地理空间使用
Pub Date : 2021-12-31 DOI: 10.22146/jmpf.66692
D. A. Puspandari, Hermawati Setiyaningsih, Zafria Atsna, T. Andayani
Tuberculosis (TB) is an infectious disease that causes a high mortality rate. Currently, Indonesia is the largest contributor to TB cases in the world. In 2019, the estimated number of cases was 845,000 cases, while case enrollment was 562,000. Thus, the Gap in the Case finding is high. As a result, innovation is needed in setting strategies to develop Regulations related to the national TB program, one of which is geospatial. This study aimed to provide an overview of geospatial utilization through HDSS in tuberculosis patients about drug management. Geospatial is an epidemiological approach that can be used to determine policies in accordance with conditions in an area. The research type is a quantitative study using secondary data from the Health and Demography Surveillance System (HDSS) of Sleman in 2016 and the Integrated TB Information System (SITT) of Sleman Regency in 2016. The analysis used descriptive analysis and geospatial mapping used Stata 15 and R software. Geospatial data shows that TB cases are concentrated in densely populated areas, such as Depok, Mlati, Ngaglik, and Gamping sub-districts. In addition, geospatial shows us the distance between the distribution of cases and the availability of health service facilities (puskesmas). The spread of cases is mostly found in the area around the health facilities, and low cases are in areas far from the health facilities. This condition possibly happens because case tracking is less affordable. Knowing the number and distribution of TB cases and the distribution of health care facilities can be used as a basis in the policy-making process, planning of the need for TB drugs, drug distribution, and priority interventions for TB services in a cost-efficiency.
肺结核是一种导致高死亡率的传染病。目前,印度尼西亚是世界上结核病病例最多的国家。2019年,估计病例数为84.5万例,而病例登记人数为56.2万。因此,案件中的差距调查结果很高。因此,需要在制定与国家结核病计划相关的法规的战略方面进行创新,其中之一就是地理空间。本研究旨在概述HDSS在结核病患者药物管理方面的地理空间利用情况。地理空间是一种流行病学方法,可用于根据某个地区的情况确定政策。该研究类型是一项定量研究,使用了2016年Sleman健康和人口监测系统(HDSS)和2016年Slerman Regency综合结核病信息系统(SITT)的二次数据。分析采用描述性分析,地理空间制图采用Stata 15和R软件。地理空间数据显示,结核病病例集中在人口稠密地区,如德波克、姆拉蒂、恩加利克和甘平分区。此外,地理空间向我们展示了病例分布与卫生服务设施可用性之间的距离。病例的传播主要发生在卫生设施周围的地区,低病例发生在远离卫生设施的地区。这种情况的发生可能是因为病例追踪成本较低。了解结核病病例的数量和分布以及卫生保健设施的分布,可以作为决策过程、结核病药物需求规划、药物分配和结核病服务优先干预措施的基础。
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引用次数: 2
Implementasi Standar Pelayanan Kefarmasian di Apotek Kupang 在库邦药房实现了标准的药物服务
Pub Date : 2021-09-30 DOI: 10.22146/JMPF.65738
Maria Meliana Waty Parera, S. A. Kristina, N. M. Yasin
According to applicable standards, pharmaceutical services strongly support the role of pharmacists in realizing quality pharmaceutical services to protect patients and the community and provide legal certainty for pharmaceutical personnel. This study aims to evaluate the implementation of pharmaceutical service standards in pharmacies by pharmacists in Kupang City. This study uses a quantitative descriptive approach. Data were collected using a questionnaire adapted from Regulation of the Minister of Health Number 73 of 2016 concerning Pharmaceutical Service Standards in Pharmacies. The population in this study were all pharmacies in Kupang City, totaling 90 pharmacies based on data from the Health Service, with valid pharmacy permits. Respondents are pharmacists who have a valid practice license in pharmacies and are willing to participate in the survey. A total of 66 respondents returned the questionnaire, and 64 were declared complete and qualified for analysis. Data were analyzed using univariate analysis with SSPS 25. The results showed that 53.75% of pharmacies in Kupang City had implemented pharmaceutical service standards in pharmacies by Regulation of the Minister of Health Number 73 of 2016, while 46.25% have not implemented service standards properly. Pharmacies that manage pharmaceutical preparations, medical equipment, and disposable medical equipment (BMHP) according to standards are 66.1%, and clinical pharmacy services are 41.4%. The conclusion shows that pharmaceutical service standards in pharmacies have not been carried out optimally by pharmacists in Kupang City.
根据适用的标准,药学服务部门大力支持药师在实现优质药学服务中的作用,以保护患者和社区,并为药学人员提供法律确定性。本研究旨在评估姑邦市药师对药房药学服务标准的执行情况。本研究采用定量描述方法。数据收集使用的调查问卷改编自卫生部2016年第73号《关于药房药品服务标准的条例》。本研究的人群均为库邦市的药店,根据卫生服务部门的数据,共有90家拥有有效药房许可证的药店。受访者为持有有效药房执业许可证并愿意参加调查的药师。共有66名受访者返回问卷,其中64名被宣布完整并符合分析条件。数据采用sssp25单因素分析。结果显示,库邦市53.75%的药店执行了卫生部2016年第73号条例规定的药店药学服务标准,46.25%的药店执行不到位。按标准管理制剂、医疗器械、一次性医疗器械(BMHP)的药店占66.1%,临床药学服务占41.4%。结果表明,库邦市药师对药店药学服务标准的执行力度不够。
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引用次数: 0
Studi Potensi Interaksi Obat pada Resep Polifarmasi di Dua Apotek Kota Bandung 两县多药复方药物相互作用的研究潜力
Pub Date : 2021-09-30 DOI: 10.22146/jmpf.56931
Irianti Bahana Maulida Reyaan, Cempaka Kuning, I. K. Adnyana
Polypharmacy prescription very commonly occurs on patient’s prescription in every health facilities. Polypharmacy may increase the risk of Drug-drug Interactions (DDI’s) which mostly causes harm impact in the patient’s therapy. Drug interactions considered clinically significant if it increases the toxicity or decreases the effectiveness of therapy. The objective of this study was to analyze the potential drug interactions in polypharmacy prescriptions in two pharmacy at Bandung city in general, based on the severity, and mechanism. This study was a non-experimental study that was carried out retrospectively by taken prescription data that received by two Pharmacies in Bandung City for the period of October- December 2018. Samples were obtained by purposive sampling technique and were analyzed by using Stockley’s Drug Interaction 9th Edition and database such as micromedexsolutions.com to determine the potential for drug interactions based on its severity and mechanism of interactions. A total of 1218 prescriptions were analyzed,  of which 896 prescription  (73.56%) were included in the inclusion criteria, and 569 prescription (63.50%) had potential drug-drug interactions. Based on the severity, majority of drug-drug interaction is moderate (85.60%), followed by minor interactions (9.28%), and major interactions (5.12%). Based on the mechanism, majority of drug-drug interactions is pharmacodynamic interactions (90.34%), and followed by pharmacokinetic interactions (9.66%). Based on the many of potential drug interactions, polypharmacy prescribing should be avoided and management of potential DDI’s should be performed.
在每个医疗机构,多药处方通常出现在患者的处方上。多药治疗可能会增加药物相互作用(DDI)的风险,这在患者的治疗中主要会造成伤害。如果药物相互作用增加毒性或降低治疗有效性,则被认为具有临床意义。本研究的目的是基于严重程度和机制,分析万隆市两个药房多药处方中的潜在药物相互作用。本研究是一项非实验性研究,根据万隆市两家药店在2018年10月至12月期间收到的处方数据进行回顾性研究。样品通过有目的的采样技术获得,并使用Stockley的药物相互作用第九版和micromedexsolutions.com等数据库进行分析,以根据药物相互作用的严重程度和机制确定其潜在相互作用。共分析了1218个处方,其中896个处方(73.56%)被纳入纳入标准,569个处方(63.50%)具有潜在的药物相互作用。根据严重程度,大多数药物-药物相互作用为中度(85.60%),其次为次要相互作用(9.28%)和主要相互作用(5.12%)。根据机制,大多数药物相互作用是药效学相互作用(90.34%),其次是药代动力学相互作用(9.66%)。基于许多潜在的药物相互作用,应避免多药处方,并对潜在的DDI进行管理。
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引用次数: 1
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Jurnal Manajemen dan Pelayanan Farmasi
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