Y. Anggriani, P. Sarnianto, S. Aisyah, Jenny Pontoan
In 2013, Ministry of Health, Republic of Indonesia, launched a new change to drug procurement system, namely e-catalogue, to ensure the availability and affordability of medicines. This system replaces the previous auction drug procurement system. The purpose of the change into e-catalogue system is to facilitate the drug procurement in hospitals without the need to conduct complex negotiation with producers, to reduce the occurrence of mark-ups or inflating drug prices, to equalize drug prices, to support BPJS (Badan Penyelenggara Jaminan Sosial) activities, and to prevent difficulties in drug distribution in all regions in Indonesia. This study aims to get an overview and magnitude of the impact of e-catalogue application on changes in the price of drugs registered and not registered in e-catalogue at Jakarta Islamic Hospital Cempaka Putih. This research is a longitudinal time series study. The data collection was conducted retrospectively in the period of 2011-2015 taken from procurement data, purchase invoices, and e-catalogue prices from hospital pharmacy installation, which were then categorized based on similar drugs in the hospital. The result shows a decrease in the price of drugs on both e-catalogue drugs (generic, trade names and patents) and non e-catalogue drugs (generic, trade names). On the class of therapy, the biggest price reduction occurred in e-catalogue medicine, such as in antineoplastics, intravenous solution, diabetes, Anti-ashma & COPD, and psycholeptics therapy. Meanwhile, on the category of non e-catalogue, price reduction occurred in systemic antibacterials, antineoplastics, analgesics, cardiac theraphy, and A-acis A-flat A Ulcerants therapy. The magnitude of drug prices reduction ranges from 1% to more than 90% both on e-catalogue drugs and non e-catalogue drugs. On the e-catalogue drugs, the highest price reduction (82.36%) occurred in generic and patent drugs, while on non e-catalogue drugs, reduction occurred in drugs with trade names. The price reduction trend in drug prices based on both type of drugs and therapy class shows a significant decrease in drug prices in the period after the implementation of e-catalogue at Jakarta Islamic Hospital in Cempaka Putih, with a decrease of more than 80%.
{"title":"Trend Price Analysis of Drug Before and After the Implementation of E-catalogue at the Hospital","authors":"Y. Anggriani, P. Sarnianto, S. Aisyah, Jenny Pontoan","doi":"10.22146/JMPF.44496","DOIUrl":"https://doi.org/10.22146/JMPF.44496","url":null,"abstract":"In 2013, Ministry of Health, Republic of Indonesia, launched a new change to drug procurement system, namely e-catalogue, to ensure the availability and affordability of medicines. This system replaces the previous auction drug procurement system. The purpose of the change into e-catalogue system is to facilitate the drug procurement in hospitals without the need to conduct complex negotiation with producers, to reduce the occurrence of mark-ups or inflating drug prices, to equalize drug prices, to support BPJS (Badan Penyelenggara Jaminan Sosial) activities, and to prevent difficulties in drug distribution in all regions in Indonesia. This study aims to get an overview and magnitude of the impact of e-catalogue application on changes in the price of drugs registered and not registered in e-catalogue at Jakarta Islamic Hospital Cempaka Putih. This research is a longitudinal time series study. The data collection was conducted retrospectively in the period of 2011-2015 taken from procurement data, purchase invoices, and e-catalogue prices from hospital pharmacy installation, which were then categorized based on similar drugs in the hospital. The result shows a decrease in the price of drugs on both e-catalogue drugs (generic, trade names and patents) and non e-catalogue drugs (generic, trade names). On the class of therapy, the biggest price reduction occurred in e-catalogue medicine, such as in antineoplastics, intravenous solution, diabetes, Anti-ashma & COPD, and psycholeptics therapy. Meanwhile, on the category of non e-catalogue, price reduction occurred in systemic antibacterials, antineoplastics, analgesics, cardiac theraphy, and A-acis A-flat A Ulcerants therapy. The magnitude of drug prices reduction ranges from 1% to more than 90% both on e-catalogue drugs and non e-catalogue drugs. On the e-catalogue drugs, the highest price reduction (82.36%) occurred in generic and patent drugs, while on non e-catalogue drugs, reduction occurred in drugs with trade names. The price reduction trend in drug prices based on both type of drugs and therapy class shows a significant decrease in drug prices in the period after the implementation of e-catalogue at Jakarta Islamic Hospital in Cempaka Putih, with a decrease of more than 80%.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44383101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patients with Acute Kidney Injury (AKI) experience changes in unstable kidney function which is characterized by instability of serum creatinine values that affect the concentration of drugs in the body. Therefore, adjusting the dosage and frequency of the drug is an important concern. This study aimed to determine the proportion of rational drug dosage regimens in hospitalized patients with AKI. This research was a retrospective observation study with cross sectional design. Sample collection was carried out using simple random sampling method for patients who were hospitalized with AKI during January 1st till December 31, 2017. Data analysis was carried out descriptively to see the proportion and description of the rationality of each dosage regimen given to patients. This research was conducted at the dr. Sardjito General Hospital Yogyakarta. The results showed that the proportion of rational drug dosage regimens given to 100 inpatients with AKI was 60.00% based on literature and 94.12% based on predictive steady-state concentration calculation. Irrationality of the dosing regimen because of administration interval was 52.84%; because of dose was 17.05%; and because of both were 30.11%. The irrationality based on predictive steady concentration showed that drug concentration below minimum effective concentration was 33.33% and over minimum toxic concentration was 66.67%. The proportion of rational drug dosage regimens given to 100 inpatients with AKI based on literature and calculation of predictive steady-state concentrations were quite high. However, some dosing regimens were still irrationally prescribed with the irrationality form were generally in the form of irrational delivery interval with excessive drug concentration.
{"title":"Drug Dosing Rationality Based on Jelliffe Equation in Acute Kidney Injury","authors":"Dealinda Husnasya, M. Ihsan","doi":"10.22146/JMPF.39921","DOIUrl":"https://doi.org/10.22146/JMPF.39921","url":null,"abstract":"Patients with Acute Kidney Injury (AKI) experience changes in unstable kidney function which is characterized by instability of serum creatinine values that affect the concentration of drugs in the body. Therefore, adjusting the dosage and frequency of the drug is an important concern. This study aimed to determine the proportion of rational drug dosage regimens in hospitalized patients with AKI. This research was a retrospective observation study with cross sectional design. Sample collection was carried out using simple random sampling method for patients who were hospitalized with AKI during January 1st till December 31, 2017. Data analysis was carried out descriptively to see the proportion and description of the rationality of each dosage regimen given to patients. This research was conducted at the dr. Sardjito General Hospital Yogyakarta. The results showed that the proportion of rational drug dosage regimens given to 100 inpatients with AKI was 60.00% based on literature and 94.12% based on predictive steady-state concentration calculation. Irrationality of the dosing regimen because of administration interval was 52.84%; because of dose was 17.05%; and because of both were 30.11%. The irrationality based on predictive steady concentration showed that drug concentration below minimum effective concentration was 33.33% and over minimum toxic concentration was 66.67%. The proportion of rational drug dosage regimens given to 100 inpatients with AKI based on literature and calculation of predictive steady-state concentrations were quite high. However, some dosing regimens were still irrationally prescribed with the irrationality form were generally in the form of irrational delivery interval with excessive drug concentration.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44979129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maternal mortality in Indonesia is relatively high, hypertension becomes one of the causes. Hypertension and complication give particular contribution on morbidity and mortality on neonatal and maternal. On the other hand, antihypertensive drug use in pregnancy has both benefit and risk. Therefore, appropriate hypertension management needs to be assesed in order to minimize the risk in mother and baby. The aim of the study is to determine the utilization pattern of antihypertensive drugs that will be assesed for suitability with the standard of medical service and American College of Obstetrics and Gynecologists (ACOG) guideline, as well as to determine clinical outcome of the therapy, which includes achieving target blood pressure, proteinuria, and edema. This study was a cross-sectional study with retrospective data collected from hospitalized patients’ medical record in RS PKU Muhammadiyah Yogyakarta from 2012 – 2015. The data of patients’ medical records according to inclusion and exclusion criteria was obtained using consecutive sampling method. Data obtained was analyzed descriptively and reviewed with the suitability of standard of medical service and ACOG guideline. Research shows that most widely used antihypertensive drugs are nifedipine by 51,8%, methyldopa by 2,6%, and amlodipine by 2,6%. Based on the evaluation of sensibility of treatment, 75,3% stated right indication, 100% right patient, and right medication and dosage. Clinical outcome includes blood pressure that had achieved the target as many as 77 patient, with negative value of proteinuria and edema. Blood pressure when patients were dismissed from the hospital was on average of 128,9±15,9/85±10,9 mmHg. In general, the utilization pattern of hypertension drugs in pregnant women has been well and according to the standards used.
{"title":"Explorative Study on Hipertension Treatment among Pregnant Women","authors":"Anis Ristyaningsih, Fivy Kurniawati, N. M. Yasin","doi":"10.22146/JMPF.40929","DOIUrl":"https://doi.org/10.22146/JMPF.40929","url":null,"abstract":"Maternal mortality in Indonesia is relatively high, hypertension becomes one of the causes. Hypertension and complication give particular contribution on morbidity and mortality on neonatal and maternal. On the other hand, antihypertensive drug use in pregnancy has both benefit and risk. Therefore, appropriate hypertension management needs to be assesed in order to minimize the risk in mother and baby. The aim of the study is to determine the utilization pattern of antihypertensive drugs that will be assesed for suitability with the standard of medical service and American College of Obstetrics and Gynecologists (ACOG) guideline, as well as to determine clinical outcome of the therapy, which includes achieving target blood pressure, proteinuria, and edema. This study was a cross-sectional study with retrospective data collected from hospitalized patients’ medical record in RS PKU Muhammadiyah Yogyakarta from 2012 – 2015. The data of patients’ medical records according to inclusion and exclusion criteria was obtained using consecutive sampling method. Data obtained was analyzed descriptively and reviewed with the suitability of standard of medical service and ACOG guideline. Research shows that most widely used antihypertensive drugs are nifedipine by 51,8%, methyldopa by 2,6%, and amlodipine by 2,6%. Based on the evaluation of sensibility of treatment, 75,3% stated right indication, 100% right patient, and right medication and dosage. Clinical outcome includes blood pressure that had achieved the target as many as 77 patient, with negative value of proteinuria and edema. Blood pressure when patients were dismissed from the hospital was on average of 128,9±15,9/85±10,9 mmHg. In general, the utilization pattern of hypertension drugs in pregnant women has been well and according to the standards used.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48713590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Citraningtyas, Ranny Inggrid Ruru, Amelia Nalang
Diarrhea is a disease characterized by a change in the shape and consistency of stools, from soft to liquid, and increased frequency of bowel movements, which happen three times or more in a day. Different use of antibiotics by patients results in patient’s medical cost increase. The use of expensive antibiotics does not guarantee the effectiveness of patient care, therefore a research needs to be done to determine which antibiotic therapy is more cost effective between cefixime and cefotaxime antibiotics in hospitalized diarrhea patients in X hospital. This research was descriptive research with retrospective data retrieval. This research was conducted at Medical Record Installation and Fund mobilization department of X hospital from November 2017 - Maret 2018. The samples in this study were 42 patients with 21 patients using Cefixime and 21 patients were using an Cefotaxime. Data was analyzed descriptively in table form. The results showed that the more cost-effective therapy between Cefixime and Cefotaxime in the treatment of diarrhea in X hospital was therapy with Cefixime antibiotic, which can be seen from ACER (Average Cost-Effectiveness Ratio) Cefixime Rp. 323.428,14/day compared with Cefotaxime ACER value of Rp. 477.180,26/day for each increase in effectiveness. The lowest ICER value on Cefixime was Rp. -50.565,8.-
{"title":"Cost Effectiveness Analysis Using Antibiotics of Cefixime and Cefotaxime for Diarrhea Patients at X Hospital in 2017","authors":"G. Citraningtyas, Ranny Inggrid Ruru, Amelia Nalang","doi":"10.22146/JMPF.36258","DOIUrl":"https://doi.org/10.22146/JMPF.36258","url":null,"abstract":"Diarrhea is a disease characterized by a change in the shape and consistency of stools, from soft to liquid, and increased frequency of bowel movements, which happen three times or more in a day. Different use of antibiotics by patients results in patient’s medical cost increase. The use of expensive antibiotics does not guarantee the effectiveness of patient care, therefore a research needs to be done to determine which antibiotic therapy is more cost effective between cefixime and cefotaxime antibiotics in hospitalized diarrhea patients in X hospital. This research was descriptive research with retrospective data retrieval. This research was conducted at Medical Record Installation and Fund mobilization department of X hospital from November 2017 - Maret 2018. The samples in this study were 42 patients with 21 patients using Cefixime and 21 patients were using an Cefotaxime. Data was analyzed descriptively in table form. The results showed that the more cost-effective therapy between Cefixime and Cefotaxime in the treatment of diarrhea in X hospital was therapy with Cefixime antibiotic, which can be seen from ACER (Average Cost-Effectiveness Ratio) Cefixime Rp. 323.428,14/day compared with Cefotaxime ACER value of Rp. 477.180,26/day for each increase in effectiveness. The lowest ICER value on Cefixime was Rp. -50.565,8.-","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45001469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Unit Dose Dispensing (UDD) is a drug distribution system in hospitals, where drugs are packaged in the form of a single dose and submitted to patients for one use during treatment. One of the hospitals that has applied UDD with information system utilization is Panti Rapih Hospital. The purpose of this study is to evaluate the application of UDD using Management Information System (SIM RS) with the Technology Acceptance Model (TAM) method. This research used descriptive quantitative analytic to present facts systematically. This method is also used to understand and conclude the facts more easily. Hypothesis testing was conducted to see the relationship and influence between variables. This test was conducted using Partial Least Square (PLS) analysis. The hypothesis testing applied was two-way probability with a significant level (α) of 5%. When the p-value of less than 0,05, the data is significant. In addition, the relationship between variables is seen from the original sample value. The result shows the relationship of perceived ease of use to perceived usefulness, the relationship of perceived usefulness to attitude toward using, and the relationship of perceived usefulness to behavioral intention to use has a negative and insignificant effect. On the other hand, the relationship of perceived ease of use to the attitude toward using, the relationship of attitude toward using to the behavioral intention to use, and the relationship of behavioral intention to use towards actual system usage conditions have a positive and significant effect on implementation of UDD using the SIM RS in Pharmacy Installation Panti Rapih Hospital.
{"title":"Implementation of Unit Dose Dispensing using Management Information System in Pharmacy Installation of Panti Rapih Hospital","authors":"Niken Larasati, Christina Asri Wulandadari","doi":"10.22146/JMPF.37402","DOIUrl":"https://doi.org/10.22146/JMPF.37402","url":null,"abstract":"Unit Dose Dispensing (UDD) is a drug distribution system in hospitals, where drugs are packaged in the form of a single dose and submitted to patients for one use during treatment. One of the hospitals that has applied UDD with information system utilization is Panti Rapih Hospital. The purpose of this study is to evaluate the application of UDD using Management Information System (SIM RS) with the Technology Acceptance Model (TAM) method. This research used descriptive quantitative analytic to present facts systematically. This method is also used to understand and conclude the facts more easily. Hypothesis testing was conducted to see the relationship and influence between variables. This test was conducted using Partial Least Square (PLS) analysis. The hypothesis testing applied was two-way probability with a significant level (α) of 5%. When the p-value of less than 0,05, the data is significant. In addition, the relationship between variables is seen from the original sample value. The result shows the relationship of perceived ease of use to perceived usefulness, the relationship of perceived usefulness to attitude toward using, and the relationship of perceived usefulness to behavioral intention to use has a negative and insignificant effect. On the other hand, the relationship of perceived ease of use to the attitude toward using, the relationship of attitude toward using to the behavioral intention to use, and the relationship of behavioral intention to use towards actual system usage conditions have a positive and significant effect on implementation of UDD using the SIM RS in Pharmacy Installation Panti Rapih Hospital.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47865249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
April Nuraini, R. Yulia, F. Herawati, Setiasih Setiasih
The inappropriate use of antibiotics has resulted in bacterial resistance to antibiotics. One of the factors supporting this phenomenon is the lack of patient knowledge and belief of antibiotics. The study aimed to know the relationship between knowledge and belief with adherence in using antibiotics in adult patients at Syarifah Ambami Rato Ebu Hospital, Bangkalan, based on the Health Belief Model theory. This research is observational analysis using cross-sectional study. There were 103 patients chosen by incidental sampling. Data collection about knowledge was obtained through questionnaires containing 13 questions, while one about belief used a questionnaire containing 30 valid and reliable questions. Adherence was measured by the pill count method. The relationship between knowledge and belief to adherence was analyzed using logistic regression test. The relationship between demography and adherence was analyzed using Spearman correlation test with α = 0.05. The result of this research shows that most patients had sufficient knowledge (57,2%), sufficient belief (69,9%) and adherence (55,3%). There was a significant relationship between knowledge with adherence in the use of antibiotics (p = 0.011) and a significant relationship between belief and adherence in the use of antibiotics (p = 0.046). In terms of belief, perceived benefits have a significant effect on adherence. The conclusions of this study is that there is a relationship between knowledge and belief with adherence in the use of antibiotics and in accordance with health belief model (HBM) theory.
{"title":"The Relation between Knowledge and Belief with Adult Patient’s Antibiotics Use Adherence","authors":"April Nuraini, R. Yulia, F. Herawati, Setiasih Setiasih","doi":"10.22146/JMPF.37441","DOIUrl":"https://doi.org/10.22146/JMPF.37441","url":null,"abstract":"The inappropriate use of antibiotics has resulted in bacterial resistance to antibiotics. One of the factors supporting this phenomenon is the lack of patient knowledge and belief of antibiotics. The study aimed to know the relationship between knowledge and belief with adherence in using antibiotics in adult patients at Syarifah Ambami Rato Ebu Hospital, Bangkalan, based on the Health Belief Model theory. This research is observational analysis using cross-sectional study. There were 103 patients chosen by incidental sampling. Data collection about knowledge was obtained through questionnaires containing 13 questions, while one about belief used a questionnaire containing 30 valid and reliable questions. Adherence was measured by the pill count method. The relationship between knowledge and belief to adherence was analyzed using logistic regression test. The relationship between demography and adherence was analyzed using Spearman correlation test with α = 0.05. The result of this research shows that most patients had sufficient knowledge (57,2%), sufficient belief (69,9%) and adherence (55,3%). There was a significant relationship between knowledge with adherence in the use of antibiotics (p = 0.011) and a significant relationship between belief and adherence in the use of antibiotics (p = 0.046). In terms of belief, perceived benefits have a significant effect on adherence. The conclusions of this study is that there is a relationship between knowledge and belief with adherence in the use of antibiotics and in accordance with health belief model (HBM) theory.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48878706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nia Kurnia Sholihat, M. W. Suryoputri, A. Martinus
Even though pharmaceutical care has been proven increasing patients’ quality of life, pharmacists still have barriers to implement it. Our study aims to examine factors affecting pharmacists in the community to implement pharmaceutical care using a Discrete Choice Experiment (DCE). The study was a cross-sectional study. A structured DCE questionnaire was administered to 90 community pharmacists in Banyumas district, Indonesia. Respondents were chosen using a simple random sampling method. According to the literature review and expert opinions, the following six attributes were selected: pharmacists’ confidence; willingness to implement pharmaceutical care; communication skill; knowledge and professional skill; availability of time; and availability of space in pharmacy. Eighteen choice sets were developed. Each choice sets comprised of two scenarios. Respondents were asked to choose the scenario they preferred the most. Data were analyzed using multinomial logit model. Of 90 questionnaires distributed, 67 were analyzed. Based on multinomial logit, all attributes had a significant effect on pharmacists’ preferences to implement pharmaceutical care. The findings suggested that pharmacist association should train their member to increase professional skills, as well as the management of pharmacy should provide enough space to perform pharmaceutical care.
{"title":"Factors Affecting Pharmaceutical Care Implementation by Community Pharmacist: A Discrete Choice Experiment","authors":"Nia Kurnia Sholihat, M. W. Suryoputri, A. Martinus","doi":"10.22146/jmpf.38804","DOIUrl":"https://doi.org/10.22146/jmpf.38804","url":null,"abstract":"Even though pharmaceutical care has been proven increasing patients’ quality of life, pharmacists still have barriers to implement it. Our study aims to examine factors affecting pharmacists in the community to implement pharmaceutical care using a Discrete Choice Experiment (DCE). The study was a cross-sectional study. A structured DCE questionnaire was administered to 90 community pharmacists in Banyumas district, Indonesia. Respondents were chosen using a simple random sampling method. According to the literature review and expert opinions, the following six attributes were selected: pharmacists’ confidence; willingness to implement pharmaceutical care; communication skill; knowledge and professional skill; availability of time; and availability of space in pharmacy. Eighteen choice sets were developed. Each choice sets comprised of two scenarios. Respondents were asked to choose the scenario they preferred the most. Data were analyzed using multinomial logit model. Of 90 questionnaires distributed, 67 were analyzed. Based on multinomial logit, all attributes had a significant effect on pharmacists’ preferences to implement pharmaceutical care. The findings suggested that pharmacist association should train their member to increase professional skills, as well as the management of pharmacy should provide enough space to perform pharmaceutical care.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48337407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melviya Sudianto, Dina Christin Ayuningputri, S. Yuliani
Compounding sterile preparation, especially for hospitalized pediatric patients, needs more concern due to dose adjustment. Things to be concerned about are compounding personnel, utilization of aseptic technique, and facilitation that affects the quality of sterile preparations. The aims of this study were to observe compounding process and to quality the sterile preparations for hospitalized pediatric patients in “X” Hospital, Semarang City, Indonesia. This research is an observational analitic with incidentally sampling research. Subject in this research was personnel who performed sterile preparations for hospitalized pediatric patients. Results from 114 sterile preparations which were observed in pediatric ward showed that compounding personnel (100%), facilities & infrastuctures, and sterile preparations procedure were not suitable with the Mixing Guideline for injectable drug and cytostatic (2009), hence it could impact the quality of sterile preparations. In addition, even after implementing appropriate solvent, compounding procedures, and aseptic technique had been utilized (100%), the physical incompatibility occurred was 8.77%. The pH of Ceftriaxone and Cefotaxime was similar with those in the literature, but for Omeprazole’s pH and based on sterility test, there were no bacterial growth.
{"title":"Evaluation of Compounding Sterile Preparations for Hospitalized Pediatric Patients in \"X\" Hospital Semarang City, Indonesia","authors":"Melviya Sudianto, Dina Christin Ayuningputri, S. Yuliani","doi":"10.22146/JMPF.34783","DOIUrl":"https://doi.org/10.22146/JMPF.34783","url":null,"abstract":"Compounding sterile preparation, especially for hospitalized pediatric patients, needs more concern due to dose adjustment. Things to be concerned about are compounding personnel, utilization of aseptic technique, and facilitation that affects the quality of sterile preparations. The aims of this study were to observe compounding process and to quality the sterile preparations for hospitalized pediatric patients in “X” Hospital, Semarang City, Indonesia. This research is an observational analitic with incidentally sampling research. Subject in this research was personnel who performed sterile preparations for hospitalized pediatric patients. Results from 114 sterile preparations which were observed in pediatric ward showed that compounding personnel (100%), facilities & infrastuctures, and sterile preparations procedure were not suitable with the Mixing Guideline for injectable drug and cytostatic (2009), hence it could impact the quality of sterile preparations. In addition, even after implementing appropriate solvent, compounding procedures, and aseptic technique had been utilized (100%), the physical incompatibility occurred was 8.77%. The pH of Ceftriaxone and Cefotaxime was similar with those in the literature, but for Omeprazole’s pH and based on sterility test, there were no bacterial growth.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43429606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Drug interaction is an interaction among a drug with other ingredients that prevents the drug from giving certain or expected effect. Such interaction might happen between a drug and other drugs, drugs with food, as well as drugs and disease. Potential drug interaction in patients with type 2 diabetes mellitus in some hospitals had been reported by several previous publications. This study aimed to identify the potential of drug interactions in patients with type 2 diabetes mellitus at Hospital X, South Tangerang. This paper is a descriptive research with retrospective retrieval data. Data were obtained in the form of patient medical records from July 2014 to June 2015. Data analysis was done by descriptive statistic analysis using SPSS version 16. The results showed that there were 90 medical records that fulfilled the inclusion criteria. Of these, 57.7% was found to be potential drug interaction. There are 55 drug interactions that potentially cause hypoglycemia, and there are 21 times that potentially cause hyperglycemia. The severity of interaction in moderate category was 89.39% (total of 66), and the rest was in minor category. Major categories were not found. The potential for drug interactions in type 2 diabetes mellitus patients is quite common and these findings complement the findings of previous published studies. Physicians and pharmacists as health workers who are directly related to the treatment of patients need to increase awareness of the potency of interactions of these drugs.
{"title":"Drug Interaction Potency on Type 2 Diabetes Mellitus Patient in Hospital X in South Tangerang","authors":"Yardi Saibi, D. Hasan, Verona Shaqila","doi":"10.22146/JMPF.34027","DOIUrl":"https://doi.org/10.22146/JMPF.34027","url":null,"abstract":"Drug interaction is an interaction among a drug with other ingredients that prevents the drug from giving certain or expected effect. Such interaction might happen between a drug and other drugs, drugs with food, as well as drugs and disease. Potential drug interaction in patients with type 2 diabetes mellitus in some hospitals had been reported by several previous publications. This study aimed to identify the potential of drug interactions in patients with type 2 diabetes mellitus at Hospital X, South Tangerang. This paper is a descriptive research with retrospective retrieval data. Data were obtained in the form of patient medical records from July 2014 to June 2015. Data analysis was done by descriptive statistic analysis using SPSS version 16. The results showed that there were 90 medical records that fulfilled the inclusion criteria. Of these, 57.7% was found to be potential drug interaction. There are 55 drug interactions that potentially cause hypoglycemia, and there are 21 times that potentially cause hyperglycemia. The severity of interaction in moderate category was 89.39% (total of 66), and the rest was in minor category. Major categories were not found. The potential for drug interactions in type 2 diabetes mellitus patients is quite common and these findings complement the findings of previous published studies. Physicians and pharmacists as health workers who are directly related to the treatment of patients need to increase awareness of the potency of interactions of these drugs.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45339180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antiretroviral (ARV) therapy can increase life expectancy of people living with HIV/AIDS (PLWHA). If the therapy fails and causes severe toxicity to first-line ARV, the first-line ARV regimen is switched to the second line. Studies on the outcome of the second-line ARV therapy have not been widely conducted in Indonesia. This study aims to identify the comparison of outcomes of the second-line ARV therapy regimens in HIV/AIDS patients. The study employed retrospective cohort design. Medical record data were collected from patients treated from January 2008 until December 2017 at Dr. Kariadi Hospital of Semarang. The number of samples that met the inclusion criteria was 42 patients. The comparison between incidence of opportunistic infections and survival among the regimens was presented descriptively. The comparison of regimens based on changes in CD4 level was performed by using Kruskal-Wallis test. The switch occurred in 24 patients (57.14%) due to toxicity of the first-line ARV and in 18 patients (42.86%) due to treatment failure. Mean CD4 and viral load during the switches were 164.68 ± 204.98 cells/mm3, 154,726.14 ± 296,797.12 copies/ml respectively. After 6 months of the second-line ARV therapy, there was an increase in CD4 level (p 0.05) among the three regimens after 6 months of the second-line ARV therapy.
{"title":"Comparison of Treatment Outcomes among Second-Line Antiretroviral Regimens in HIV/AIDS Patient","authors":"Winda Dwi Puspitasari, N. M. Yasin, F. Rahmawati","doi":"10.22146/JMPF.36414","DOIUrl":"https://doi.org/10.22146/JMPF.36414","url":null,"abstract":"Antiretroviral (ARV) therapy can increase life expectancy of people living with HIV/AIDS (PLWHA). If the therapy fails and causes severe toxicity to first-line ARV, the first-line ARV regimen is switched to the second line. Studies on the outcome of the second-line ARV therapy have not been widely conducted in Indonesia. This study aims to identify the comparison of outcomes of the second-line ARV therapy regimens in HIV/AIDS patients. The study employed retrospective cohort design. Medical record data were collected from patients treated from January 2008 until December 2017 at Dr. Kariadi Hospital of Semarang. The number of samples that met the inclusion criteria was 42 patients. The comparison between incidence of opportunistic infections and survival among the regimens was presented descriptively. The comparison of regimens based on changes in CD4 level was performed by using Kruskal-Wallis test. The switch occurred in 24 patients (57.14%) due to toxicity of the first-line ARV and in 18 patients (42.86%) due to treatment failure. Mean CD4 and viral load during the switches were 164.68 ± 204.98 cells/mm3, 154,726.14 ± 296,797.12 copies/ml respectively. After 6 months of the second-line ARV therapy, there was an increase in CD4 level (p 0.05) among the three regimens after 6 months of the second-line ARV therapy.","PeriodicalId":33008,"journal":{"name":"Jurnal Manajemen dan Pelayanan Farmasi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49414523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：