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Pengembangan Kuisioner Udayana untuk Penilaian Kepuasan Pasien terhadap Pelayanan Kefarmasian oleh Apoteker di Pusat Kesehatan Masyarakat 乌达亚纳的药师在公共卫生中心对病人的药物服务的满意度进行了问卷调查
Pub Date : 2021-03-31 DOI: 10.22146/JMPF.60998
L. Larasanty, M. Jaya, K. W. Astuti, I. Santika
The implementation of pharmaceutical care by pharmacists at the community health center has been regulated in the Minister of Health Regulation No. 74 of 2016. Based on that regulation, assessment of pharmaceutical care services is needed to ensure the quality of services provided by pharmacists. This study aims to develop an Udayana questionnaire that can be used to evaluate the quality of pharmaceutical care provided by pharmacists at community health centers. This research is quantitative (survey implementation) carried out in 2 phases. The first phase is the design of the Udayana questionnaire. The second phase is to verify the validity and reliability of the questionnaire. The questionnaire validity test was carried out in three stages, namely the logical validity test, content validity, and construct validity. The questionnaire statement develop based on Minister of Health Regulation No. 74 of 2016 obtained 31 statements which are divided into 5 dimensions of service quality. The logical validity test resulted in 30 statements that were declared valid by experts. Content validity test is done by calculating the value of the content validity ratio (CVR) and the value of the content validity index (CVI). The CVR and CVI results showed that 7 statements were eliminated because they were not valid (CVR value <0.99 and CVI <70%). Construct validity test and questionnaire reliability were tested on 384 respondents who had met the inclusion criteria. The construct validity test resulted 23 valid statement (r = 0.148). Results of the reliability test based on Cronbach's Alpha value is greater than 0.6, indicating that all the valid statement items in the Udayana questionnaire are reliable. Based on the results of validity and reliability tests, 23 statements of Udayana's questionnaire are stated valid and reliable and can be used to evaluate the quality of pharmaceutical care at the community health center.
卫生部长2016年第74号条例对药剂师在社区卫生中心实施药物护理进行了规定。根据该条例,需要对药物护理服务进行评估,以确保药剂师提供的服务质量。本研究旨在开发一份Udayana问卷,用于评估社区卫生中心药剂师提供的药物护理质量。本研究分两个阶段进行定量研究(调查实施)。第一阶段是Udayana问卷的设计。第二阶段是验证问卷的有效性和可靠性。问卷有效性测试分为三个阶段进行,即逻辑有效性测试、内容有效性测试和结构有效性测试。根据卫生部2016年第74号条例制定的调查表共获得31份,分为服务质量的5个维度。逻辑有效性测试得出了30项声明,专家们宣布这些声明有效。内容有效性测试是通过计算内容有效性比率(CVR)的值和内容有效性指数(CVI)的值来进行的。CVR和CVI结果显示,有7项陈述因无效而被删除(CVR值<0.99,CVI<70%)。对384名符合纳入标准的受访者进行了结构有效性测试和问卷信度测试。结构有效性检验得到23个有效陈述(r=0.148)。基于Cronbach’s Alpha值的信度检验结果大于0.6,表明Udayana问卷中的所有有效陈述项目都是可靠的。根据有效性和可靠性测试结果,Udayana问卷中的23项陈述是有效和可靠的,可用于评估社区卫生中心的药物护理质量。
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引用次数: 0
A Scoping Review of Disposal of Unused Medicines in Take-Back Programs 回收计划中未使用药物处置的范围审查
Pub Date : 2021-03-31 DOI: 10.22146/JMPF.61343
Mufti Alifia Rahmadani, S. A. Kristina
Unused medicines in the household cause many problems. Medicines take-back programs were established to prevent inappropriate medicines disposal, abuse, accidental poisoning, and help reduce the number of unused medicines in households. A literature search using the keywords “unused AND medicine”, “disposal AND unused AND medicine”, “reasons AND medicine AND disposal”, “medicine AND take-back program” and “cost AND medicine AND take-back program” in PubMed, Science Direct, Scopus and Google Scholar. Articles published in 2010 – 2020 in English report the medicine take-back program with the number of medicines and/or reasons for the return and/or economic value of medicines collected in the medicines take-back program. A total of 16 articles were included in the criteria for this systematic review. Medicines take-back program was majority-owned in the US (69%). Two programs focus on returning controlled medicines. Gastrointestinal, respiratory, cardiovascular, antimicrobial and non-narcotic analgesic were the most common of all medicines returned. The expired medicine and treatment discontinuation by (doctors/prescribers) were the most reason medicine was returned to the medicines take-back program. The total cost of all medicines returned topped $1,118,020. Medicines take-back program was an essential solution to the inappropriate medicine disposal problem. Good coordination was required between the government and other authorities.This medicine take-back issues can help solve the problems of medicine use, storage, and disposal that lead to the country's economy.
家庭中未使用的药物会造成许多问题。制定了药品回收计划,以防止不适当的药品处理、滥用、意外中毒,并帮助减少家庭中未使用的药品数量。在PubMed、Science Direct、Scopus和Google Scholar中使用关键词“未使用的AND药物”、“处置和未使用的AND-药物”、”原因与药物AND处置“、”药物与收回计划“和”成本与药物与收回程序“进行文献检索。2010-2020年发表的英文文章报告了药品回收计划,包括药品数量和/或退货原因和/或药品回收计划中收集的药品的经济价值。共有16篇文章被纳入本系统综述的标准。药品回收计划在美国拥有多数股权(69%)。有两个项目侧重于退回受管制药物。胃肠道、呼吸系统、心血管、抗菌和非麻醉性镇痛药是所有退回药物中最常见的。过期药物和(医生/处方医生)停止治疗是药物被退回药品回收计划的主要原因。所有退回药品的总费用超过1118020美元。药品回收计划是解决药品处置不当问题的重要办法。政府和其他当局之间需要进行良好的协调。这种药品回收问题可以帮助解决导致国家经济发展的药品使用、储存和处置问题。
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引用次数: 3
Apa yang direkomendasikan apoteker untuk tatalaksana diare akut pada anak? Sebuah survei di wilayah timur Kota Surabaya 药剂师建议对儿童进行什么急性腹泻治疗?在泗水东部地区进行的一项调查
Pub Date : 2021-03-31 DOI: 10.22146/JMPF.59719
Linda Fidya Ningsih, Adji Prayitno Setiadi, Abd Rahem, Cecilia Brata, Yosi Irawati Wibowo, E. Setiawan, S. V. Halim
Appropiate recommendation provided by pharmacists is considered as a crucial factors to prevent morbidity and mortality among children with acute diarrhea in the community. This study aimed to determine the type and the appropriateness of recommendations provided by the community pharmacists in the eastern part of Surabaya to children presenting with acute diarrhea. This was cross-sectional study conducted by using a questionnaire consisting of questions about participants’ characteristics and a case of acute diarrhea in children without complications and other “alarm symptoms” requiring medical referral. The appropriate recommendation for the case was to give a combination of oral rehydration solution (ORS) and zinc with or without other recommendations. Data were analyzed descriptively using SPSS version 22. A total of 84 pharmacists provided consent to be participants in this study. The majority of participants (73,81%) were pharmacists manager and more than 50% of them completed pharmacist professional degree between 2010 and 2019. Type of pharmacists’ recommendations were further classified as: medical referral, provision of medicine, laboratory testing, and non-pharmacology treatment. The most provided recommendations were provision of medicine (97,62%) with or without other recommendations. Medical referral were recommended by 22 pharmacists (26,19%). Of the total participants, 13,09% provided appropriate recommendations. Findings of this study indicate the necessity to optimise the role of community pharmacists in managing acute diarrhea in children. Further study to identify the needs of community pharmacists, either conducted with qualitative or quantitative approach, is required as the key step before implementing further intervention.
药剂师提供的适当建议被认为是预防社区急性腹泻儿童发病和死亡的关键因素。本研究旨在确定泗水东部社区药剂师为急性腹泻儿童提供的建议的类型和适当性。这是一项横断面研究,采用问卷调查,包括参与者的特征和一例儿童急性腹泻,无并发症和其他需要转诊的“警报症状”。对于这种情况,适当的建议是给予口服补液(ORS)和锌的组合,有或没有其他建议。数据采用SPSS version 22进行描述性分析。共有84名药师同意参与本研究。大多数参与者(73.81%)是药剂师经理,其中超过50%的人在2010年至2019年期间完成了药剂师专业学位。药师建议的类型进一步分为:转诊、提供药物、实验室检测和非药物治疗。提供最多的建议是提供有或没有其他建议的药物(97,62%)。推荐转诊的药师有22名(26.19%)。在所有参与者中,有13.09%的人提供了适当的建议。本研究结果表明,有必要优化社区药师在管理儿童急性腹泻中的作用。在实施进一步干预措施之前,需要进一步研究以确定社区药剂师的需求,无论是采用定性还是定量方法。
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引用次数: 4
Outpatient Parenteral Antimicrobial Treatment sebagai Upaya Menurunkan Biaya Pasien Ulkus Diabetik yang Terinfeksi 出口药物治疗以降低受感染的糖尿病溃疡患者的成本
Pub Date : 2021-03-31 DOI: 10.22146/JMPF.60256
Hemi Sinorita, Rizka Humardewayanti Asdie, T. Hartati, Pebriati Sumarningsih, T. Rahayu, Ika Puspitasari
Ulkus diabetik  terinfeksi memerlukan terapi antibiotik yang tepat untuk menghindari risiko amputasi. Tujuan utama program Outpatient Parenteral Antimicrobial Treatment (OPAT) adalah memungkinkan pasien memperoleh terapi antibiotik parenteral dengan aman dan efektif tanpa menjalani rawat inap. Penelitian ini bertujuan untuk mengetahui perbedaan biaya pemberian antibiotika parenteral dan kualitas hidup pasien antara pasien ulkus diabetik terinfeksi yang memperoleh pelayanan rawat inap dan OPAT. Penelitian ini menggunakan rancangan penelitian ini adalah quasi experimental pada pasien ulkus diabetika yang terinfeksi di di RSUP dr. Sardjito Agustus 2019 sampai April 2020 dengan kriteria inklusi pasien umur ≥ 18 tahun; kondisi klinis stabil; sudah didapatkan hasil kultur swab dasar luka, dengan kriteria eksklusi pasien imunocompromised (pasien kanker dan pasien transplantasi organ yang mendapatkan terapi imunosuppresan serta pasien HIV). Pasien mendapat perawatan luka dua kali dalam seminggu di poliklinik endokrin untuk dinilai outcome klinisnya dan pada akhir pengobatan mengisi kuisioner kualitas hidup SF36. Selanjutnya dihitung biayanya dan dianalisa perbedaan kualitas hidup serta biaya antara OPAT dibanding rawat inap. Selama penelitian terdapat 15 pasien kelompok OPAT dan 15 pasien kelompok rawat inap. Dari sisi perbaikan klinis terdapat perbedaan yang bermakna antara skor PEDIS kelompok OPAT terhadap kelompok Rawat Inap  (p = 0,007). Pembiayaan pelayanan OPAT menghemat  biaya medik langsung sebanyak 75,77% dari pembiayaan pelayanan rawat inap dengan total pelayanan OPAT sebesar Rp 2.556.117,- dan pelayanan rawat inap sebesar Rp 10.549.487,-. Terdapat  perbedaan yang bermakna pada beberapa domain kualitas hidup  yaitu domain fungsi peran emosional (p=0,045); domain fungsi sosial (p<0,01) dan score MCS (Mental Component Summary (p=0,005). OPAT meningkatkan 3 domain fungsi ini.
糖尿病性溃疡需要适当的抗生素治疗以避免截肢风险。计划的主要目标是让患者在不住院的情况下安全有效地获得肠外抗生素治疗。本研究旨在确定肠外麻醉药物的出纳成本与接受住院治疗和OPAT治疗的糖尿病溃疡患者的生活质量之间的差异。这项研究使用的是准实验研究设计得溃疡diabetika被感染的病人在2019至2020年4月和8月RSUP Sardjito博士标准包含患者年龄≥18岁;临床情况稳定;已获得基本的拭子培养物,并配以免疫合成病人的排他性(获得免疫抑制剂治疗和艾滋病毒患者的器官移植患者)。患者每周在内分泌药物诊所接受两次治疗,以评估其临床结果,并在治疗结束时填写SF36生活质量问卷。然后计算成本,分析OPAT的生活质量和住院费用之间的差异。研究期间,有15名OPAT患者和15名住院病人。从临床改进的角度来看,OPAT患者的住院病人分数(p = 0.007)有显著差异。OPAT服务融资从住院服务融资中节省了75.77%,总费用为OPAT服务,总费用为$ 2,556,117,住院服务为$ 10549,487。在一些生活质量领域中,存在着意义上的差异,即情感角色功能的领域(p= 045);社会功能域(p< 001)和得分MCS(心理Component Summary, p= 005)。OPAT增加了这三个功能域。
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引用次数: 0
Relationship between Dose and Retention of Methadon Maintenance Therapy to Drug Dependence Patients in Primary Health Care 初级卫生保健中药物依赖患者美沙酮维持治疗的剂量与保留的关系
Pub Date : 2021-03-31 DOI: 10.22146/JMPF.57922
Lili Musnelina, Jenny Pontoan, B. Prasetya
Methadon maintenance therapy is one of the substitution therapies needed as an approach to harm reduction or the reduction of the adverse effects of drug abuse. This study aims to fix the infinitive relationship doses with retention of drug dependence patients on methadon maintenance therapies program (PTRM) in Kramat Jati Primary Health Care in 2009-2018. A cross-sectional study is conducted using secondary data from medical records subsequently significance analysis. This research involves 136 patients who were included in the inclusion criteria. Results shown mean initial doses received is 27,65 mg (10-40 mg), after 2 weeks of therapy mean doses received are 51,6 mg (range 22,5 – 85 mg). Average lowest and highest maintenance dose which received is 30,9 mg (range 0,25-115 mg) dan 84,39 mg (range 7,77-126,92 mg). This research shows the retention value 1 year or more reaches 64,71%. Maintenance doses 2 weeks (P=0,005), lowest maintenance doses (P=0,000), average maintenance doses (P=0,004), and history misses doses (P=0,000) have significance with retention. The conclusion that the more optimal maintenance doses received, even more in methadone maintenance therapies. Otherwise, lower missed doses frequency better to patients retention in methadon maintenance therapies.
美沙酮维持疗法是减少伤害或减少药物滥用不良影响所需的替代疗法之一。本研究旨在确定2009-2018年Kramat Jati初级卫生保健中心美沙酮维持治疗计划(PTRM)中药物依赖患者的无限量关系剂量。横断面研究使用来自医疗记录的次要数据进行,随后进行显著性分析。这项研究涉及136名纳入纳入标准的患者。结果显示,接受的平均初始剂量为27.65 mg(10-40 mg),治疗2周后接受的平均剂量为51.6 mg(范围22.5–85 mg)。平均最低和最高维持剂量分别为30,9 mg(范围0.25-115 mg)和84,39 mg(范围7,77-126,92 mg)。本研究表明,1年或1年以上的保留值达到64,71%。维持剂量2周(P=0005)、最低维持剂量(P=0000)、平均维持剂量(P=0.004)和历史未中剂量(P=0.000)对保留具有显著意义。结论是,接受的最佳维持剂量越多,美沙酮维持治疗的效果就越好。否则,美沙酮维持治疗中漏服剂量频率越低,对患者的滞留效果越好。
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引用次数: 0
Faktor yang Berhubungan dengan Tingkat Pengetahuan Masyarakat dalam Mengelola Obat Sisa, Obat Rusak dan Obat Kedaluarsa 这一因素与人们管理剩余、变质和保质期药物的知识水平有关
Pub Date : 2021-03-31 DOI: 10.22146/JMPF.58708
Hananditia Rachma Pramestutie, Ratna Kurnia lllahi, Ayuk Lawuningtyas Hariadini, Tamara Gusti Ebtavanny, Tia Eka Aprilia
Problems that often arose as a result of improper management of unused, damaged, and expired drugs in storage and disposal, include drug abused, increased environmental damage, antibiotic resistance, and decrease effectiveness of therapy; due to the lack of public knowledge that can caused by several factors. This study aims to analyse factor associated with level knowledge in the management of unused, damaged, and expired drugs in Malang Raya. This study was an observational analytic study with a cross-sectional design. The subjects were the people of Malang Raya who were selected using a convenience sampling technique in accordance with the inclusion and exclusion criteria. The subjects were 322 respondents. The instrument used was a questionnaire to measure the level of knowledge of respondents that had been tested for validity and reliability. The results showed that, level of knowledge of respondence at Malang Raya in the management of unused, damage and expired drugs in the good (21%), sufficient (58%), and less (21%). Statistical tests used in this study were Somers'd, Kruskal-wallis, and Lambda tests to analysed factor associated with subjects’ level of knowledge in the management of unused, damaged, and expired drugs. There were a significant relationship in factors included age (p = 0.018) and income level (p = 0.003). It can be concluded that among the factors associated with  the level of knowledge in the management of unused, damaged, and expired drugs, only age and income level were statistically significant. Further study is needed to determine the factors affecting the level of knowledge the most.
由于对未使用、损坏和过期药物的储存和处置管理不当,经常出现的问题包括药物滥用、环境破坏加剧、抗生素耐药性和治疗效果下降;由于公众知识的缺乏,这可能由几个因素引起。本研究旨在分析玛琅拉雅未使用、损坏和过期药品管理中与水平知识相关的因素。本研究为横断面设计的观察性分析研究。受试者是按照纳入和排除标准采用便利抽样技术选择的玛琅拉雅居民。调查对象为322名受访者。所使用的工具是一份问卷,用于测量已经过效度和信度测试的应答者的知识水平。结果显示,玛琅拉雅受访医院对未使用、损坏和过期药品管理的知识水平为良好(21%)、充足(58%)和不足(21%)。本研究采用Somers'd、Kruskal-wallis和Lambda检验来分析与受试者未使用、损坏和过期药物管理知识水平相关的因素。年龄(p = 0.018)、收入水平(p = 0.003)等因素存在显著相关。由此可见,在影响未使用、破损、过期药品管理知识水平的因素中,只有年龄和收入水平具有统计学意义。需要进一步的研究来确定最影响知识水平的因素。
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引用次数: 2
Pengaruh Pelatihan Pelayanan Kefarmasian terhadap Pengetahuan Pengelola Obat di Puskesmas Kabupaten Ogan Komering Ilir 药物管理培训对奥根工业区毒品管理知识的影响
Pub Date : 2020-03-26 DOI: 10.22146/jmpf.50601
H. Amrullah, S. Satibi, Achmad Fudholi
The increasing number of patients admited to primary healthcare (PHC) in the JKN era demands the readiness of PHC’s staff, especially pharmaceutical staff, to serve the community. Knowledge is a major necessity in collaborating with other health profesional to improve the quality of health services. Pharmaceutical staff who lack knowledge needs special training to improve their competences in drug management and clinical pharmacy services. This study aims to determine the effect of pharmacy service training on the knowledge of drug manager in PHC’s of Ogan Komering Ilir district. This research is a quasi-experimental design research with pre and post analysis approach in the intervention group and using the control group as a comparison. Subjects in the study were drug managers in the PHC’s of Ogan Komering Ilir district that met the criteria. The intervention was carried out by providing training to drug manager and providing pharmacy service manuals. The training material provided was based on the Pharmaceutical Services Training Curriculum compiled by Ministry of Health. Another instrument used was a validated questionnaire to measure the knowledge score of drug managers before and after training. A total of 13 drug managers participated in this study. After the training, the knowledge score of drug manager in the intervention group increased from 9.83 ± 2.401 to 12.67 ± 2.333 with value of p = 0.013. The majority of intervention group drug managers experienced an increase in knowledge both from the aspect of drug management and clinical pharmacy service aspects. This study concludes that training of drug managers has an effect on increasing knowledge of aspects of drug management and clinical pharmacy services.
在JKN时代,越来越多的患者接受初级卫生保健(PHC),要求PHC的工作人员,特别是药学人员,准备好为社区服务。知识是与其他卫生专业人员合作提高卫生服务质量的重要必要条件。缺乏知识的药学人员需要进行专门培训,以提高其药品管理和临床药学服务能力。本研究旨在探讨药学服务培训对奥根科莫林伊尔区初级保健医院药品管理人员知识的影响。本研究为准实验设计研究,在干预组采用前后分析的方法,以对照组为对照。研究对象为Ogan Komering Ilir区初级保健医院的药品管理人员,符合标准。干预措施通过向药品管理人员提供培训和提供药房服务手册来实施。所提供的培训材料是根据卫生部编制的《药品服务培训课程》编写的。另一个工具是一份有效的问卷,用于测量药品管理人员培训前后的知识得分。共有13名药品管理人员参与了本研究。培训后,干预组药品管理人员知识得分由9.83±2.401提高至12.67±2.333,p = 0.013。大多数干预组药品管理人员在药品管理和临床药学服务方面的知识都有所增加。本研究的结论是,药品管理人员的培训对增加药品管理和临床药学服务方面的知识有影响。
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引用次数: 3
Analisis Efektivitas Biaya Terapi Antihipertensi Kombinasi Tetap Di Satu Rumah Sakit Jakarta Selatan 分析了雅加达南部一家医院的联合抗高血压治疗成本的有效性
Pub Date : 2020-02-29 DOI: 10.36423/pharmacoscript.v2i2.388
A. Rahayu, A. Afdhal, Delina Hasan, Feriadi Suwarna, Okpri Meila
The majority of alternative antihypertensive therapies require pharmacoeconomic studies, particularly Cost Effectiveness Analysis, which is useful in balancing patients’ expenditure by determining alternative treatments that represented the most plausible health outcomes with a more reasonable budget. The objective of this study was to compare the cost effectiveness using antihypertensive fixed dose combinations (FDC) of Valsartan-Amlodipine + Furosemide and FDC of Valsartan-HCT + Amlodipin. This research applied the descriptive analytical cross-sectional method and conducted data collection retrospectively from the medical record of hypertensive patients. Meanwhile, the medication cost breakdown was obtained from Outpatient Financial Department of a Type B Hospital in south Jakarta for the period of January - June 2018. Total sample were 74 patients, consisted of 37 patients who used  FDC of Valsartan-Amlodipin + Furosemide, and 37 patients who used FDC of Valsartan-HCT + Amlodipin. The parameters of this research were direct medication cost (consisted of examination cost, laboratory cost and medicines cost), indirect medication cost (consisted accommodation cost and lost productivity cost), while the effectiveness used the MAP average (Mean Arterial Pressure). The result of this research showed that the biggest medication effectiveness to lower the blood pressure is FDC of  Valsartan-Amlodipin + Furosemide, with 32  patients had the average MAP 101,29 mmHg, while the FDC of Valsartan-HCT + Amlodipin with 29 patients had the average MAP 103,59 mmHg. The cost effectiveness based on ACER value of  FDC of Valsartan –HCT + Amlodipin and FDC Valsartan-HCT + Amlodipin sequentially is Rp 3.922.040/MAP and Rp 4.458.034/MAP. In conclusion, the FDC of Valsartan-Amlodipin + Furosemide  was more cost-effective.
大多数替代性降压治疗需要药物经济学研究,特别是成本效益分析,通过确定替代性治疗,以更合理的预算代表最合理的健康结果,这有助于平衡患者的支出。本研究的目的是比较缬沙坦-氨氯地平+呋塞米的降压固定剂量组合(FDC)和缬沙坦HCT+氨氯地平的FDC的成本效益。本研究采用描述性分析横断面方法,对高血压患者的病历资料进行了回顾性收集。同时,从雅加达南部一家B型医院的门诊财务部获得了2018年1-6月期间的药物费用明细。总样本为74名患者,包括37名使用缬沙坦-氨氯地平+呋塞米的FDC的患者和37名使用Valsartan HCT+氨氯地平的FDC患者。本研究的参数是直接药物成本(包括检查成本、实验室成本和药物成本)、间接药物成本(包含住宿成本和生产力损失成本),而有效性使用MAP平均值(平均动脉压)。研究结果表明,降压效果最大的是缬沙坦-氨氯地平+呋塞米的FDC,32例患者的平均MAP为101,29mmHg,而缬沙坦-HCT+氨氯地平的FDC有29例患者的MAP为103,59mmHg。基于缬沙坦-HCT+Amlodipin和FDC的FDC的ACER值,缬沙坦-HCT+Amlodipin的成本效益依次为3.922.040卢比/MAP和4.458.034/MAP。总之,缬沙坦-Amlodipin+呋塞米的FDC更具成本效益。
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引用次数: 1
Penilaian Kualitas Hidup Pasien Hemodialisis Rutin dengan Anemia di Yogyakarta 日惹定期血液透析贫血患者的生活质量评估
Pub Date : 2019-09-30 DOI: 10.22146/JMPF.43187
Candra Eka Puspitasari, T. Andayani, Fredie Irijanto
Anemia is often experienced by hemodialysis patients and can have an impact on the quality of life. This study aims to determine the effect of hemoglobin (Hb), hematocrit (Ht), and the characteristics and sociodemographic of the subjects on quality of life. The method used in this study was cross sectional and consecutive sampling technique. The data is retrieved by interviews which then analyzed using dummy multiple regression. Inclusion criteria included routine hemodialysis patients and did not receive blood transfusions. The validity and reliability test of the KDQoL-SF36 questionnaire showed reliable results. The results of the study on 112 subjects obtained an increase in Hb levels positively correlated with an increase in the KDQoL-SF36 score but not for an increase in Ht levels. Increased KDQoL-SF36 score illustrates the better quality of life of patients. Characteristics and sociodemography that influence quality of life include comorbid dummy hypertension-diabetes and work status. The condition of anemia can worsen the quality of life for hemodialysis patients.
血液透析患者经常会出现贫血,并且会对生活质量产生影响。本研究旨在确定血红蛋白(Hb)、红细胞压积(Ht)以及受试者的特征和社会人口统计学对生活质量的影响。本研究中使用的方法是横截面和连续采样技术。通过访谈检索数据,然后使用伪多元回归进行分析。纳入标准包括常规血液透析患者和未接受输血的患者。KDQoL-SF36问卷的有效性和信度检验结果可靠。对112名受试者的研究结果表明,Hb水平的增加与KDQoL-SF36评分的增加呈正相关,但与Ht水平的增加无关。KDQoL-SF36评分的增加说明患者的生活质量更好。影响生活质量的特征和社会人口学包括共病伪高血压糖尿病和工作状态。贫血会使血液透析患者的生活质量恶化。
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引用次数: 3
Pengukuran Kualitas Hidup Pasien Kanker Payudara di Kota Denpasar Menggunakan Instrumen EQ-5D-5L EQ-5D-5L仪器在登巴萨市癌症乳腺癌患者生活质量检测中的应用
Pub Date : 2019-09-30 DOI: 10.22146/jmpf.47192
Abdillah Mursyid, R. Haris, Dwi Endarti, Chairun Wiedyaningsih, Susi Ari Kristina
Breast cancer is the second most common cancer in the world and is one of the biggest causes of cancer deaths every year. Measurement of the quality of life in breast cancer patients could improve treatment and become a prognosic factor along with medical parameters for the patients. This study aims to measure the life quality of breast cancer patients and observe how it affects the life quality based on patient characteristics. The study was conducted on 93 breast cancer patients. Data were collected form patients in several breast cancer comunities in Denpasar which were carried outh within 3 months (January – March 2019). This study used a cross sectional design using a snowball sampling technique involving breast cancer patients in several cancer communities in Denpasar. The patient's life quality data was obtained using the EuroQol-5 Dimension-5 Level (EQ-5D-5L) generic instrument and conversion to health utility (utility) used the Indonesian value set. The entire data was analyzed using the independent t-test and multivariate regression. The results showed that pain/discomfort and anxiety/depression were the most dominant problem in breast cancer patients (82,7%). The utility value of breast cancer patients was 0.821±0.123 and the VAS value was 74.41±11.67. There was a significant difference in utility value based on patient characteristics of occupation (p=0.035), symptoms (p=0,003), and cancer stadium (p=0.015). Affected 20.5% of the quality of life of breast cancer patients in Denpasar city.
癌症是世界上第二常见的癌症,也是每年癌症死亡的最大原因之一。测量癌症患者的生活质量可以改善治疗,并与患者的医疗参数一起成为预后因素。本研究旨在测量癌症患者的生活质量,并根据患者特点观察其对生活质量的影响。这项研究对93名癌症患者进行。数据是从登巴萨几个癌症社区的患者收集的,这些社区在3个月内(2019年1月至3月)进行了筛查。这项研究采用了一种横截面设计,使用了滚雪取样技术,涉及登巴萨几个癌症社区的癌症患者。患者的生活质量数据使用EuroQol-5维度5水平(EQ-5D-5L)通用仪器获得,并使用印尼值集转换为健康效用(效用)。使用独立t检验和多元回归对整个数据进行分析。结果显示,疼痛/不适和焦虑/抑郁是癌症患者最主要的问题(82,7%)。癌症患者的效用值为0.821±0.123,VAS值为74.41±11.67。根据患者的职业特征(p=0.035)、症状(p=0003)和癌症运动场(p=0.015),效用值存在显著差异。影响了登巴萨市20.5%的癌症乳腺癌患者的生活质量。
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Jurnal Manajemen dan Pelayanan Farmasi
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