Aim: Violent incidents have become an increasing problem in our hospitals. Many violent incidents cause devastating damage to healthcare personnel. In this study, we aimed to examine the etiological differences between physical and verbal violence in violent incidents seen in hospitals, and especially whether being an emergency service professional has an effect on physical and verbal violence. Materials and Method: Four-year white code case records between 2018 and 2022 in a tertiary hospital were retrospectively reviewed. The type and setting of violence, the gender, and the occupation of the perpetrator were recorded. The cases were divided into two groups: physical violence and verbal violence. The collected data were compared between the groups. Results: During the indicated period, 231 cases of code white were reported. While 51.9% of those affected by violence were men, the mean age was 33 (28-40). Physicians were the most common professional group affected by violence, with 102 individuals (44.2%). The most common site of violence was the emergency service, at 54.5%. The rate of physical violence in the emergency department was found to be higher than verbal violence (63.9%-51.2%), although it was not statistically significant. In cases of physical violence, the proportion of the individual exposed to violence being male was statistically significantly higher than in cases of verbal violence (43/61(70.5%), 77/170(%47) <0,001). The proportion of female perpetrators of verbal violence was statistically significantly higher than that of physical violence (35/170(20.6%), 3/61(4.9%), <0,001). Conclusion: In our study, it was found that those exposed to physical violence were mostly men. It has been determined that women use verbal violence more than physical violence. Physicians were more exposed to verbal violence. In addition, although the propotion of emergency room location in physical violence incidents was higher than in verbal violence incidents, the difference was not found to be statistically significant. Keywords: Physical violence, verbal violence, code white, emergency service
{"title":"Is Being an Emergency Service Professional a Risk Factor for Violence in Healthcare","authors":"Ali Avcı","doi":"10.30733/std.2023.01692","DOIUrl":"https://doi.org/10.30733/std.2023.01692","url":null,"abstract":"Aim: Violent incidents have become an increasing problem in our hospitals. Many violent incidents cause devastating damage to healthcare \u0000personnel. In this study, we aimed to examine the etiological differences between physical and verbal violence in violent incidents seen in \u0000hospitals, and especially whether being an emergency service professional has an effect on physical and verbal violence. \u0000Materials and Method: Four-year white code case records between 2018 and 2022 in a tertiary hospital were retrospectively reviewed. The \u0000type and setting of violence, the gender, and the occupation of the perpetrator were recorded. The cases were divided into two groups: physical \u0000violence and verbal violence. The collected data were compared between the groups. \u0000Results: During the indicated period, 231 cases of code white were reported. While 51.9% of those affected by violence were men, the mean age \u0000was 33 (28-40). Physicians were the most common professional group affected by violence, with 102 individuals (44.2%). The most common site \u0000of violence was the emergency service, at 54.5%. The rate of physical violence in the emergency department was found to be higher than verbal \u0000violence (63.9%-51.2%), although it was not statistically significant. In cases of physical violence, the proportion of the individual exposed to \u0000violence being male was statistically significantly higher than in cases of verbal violence (43/61(70.5%), 77/170(%47) <0,001). The proportion of \u0000female perpetrators of verbal violence was statistically significantly higher than that of physical violence (35/170(20.6%), 3/61(4.9%), <0,001). \u0000Conclusion: In our study, it was found that those exposed to physical violence were mostly men. It has been determined that women use verbal \u0000violence more than physical violence. Physicians were more exposed to verbal violence. In addition, although the propotion of emergency room \u0000location in physical violence incidents was higher than in verbal violence incidents, the difference was not found to be statistically significant. \u0000Keywords: Physical violence, verbal violence, code white, emergency service","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140383542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Skin and gland removals made on the chest wall may result in noticeable scars that can be challenging for patients to tolerate. This study aimed to define an extensive ultrasonic liposuction approach without surgical excision for gynecomastia. We also investigated its effectiveness in reducing complications and improving cosmetic outcomes. Materials and Methods: Gynecomastia patients with Rohrich grades II and III were evaluated according to skin quality. 46 patients who met these criteria underwent ultrasonic liposuction performed by the senior author between February 2021 and April 2023. These patients were compared with 58 who underwent surgery using suction-assisted liposuction combined with peri areolar mastopexy and glandular excision. Results: Our study found that patients who underwent extensive ultrasonic liposuction had a complication rate of 8.7%. Of the total number of patients, only one experienced a seroma complication, and three experienced residual breast tissue/ptosis. None of the patients required revision surgery. In comparison, the control group that underwent peri-areolar mastopexy and glandular excision had a higher complication rate (10.3%). Conclusion: We used the basic principles of plastic surgery for wound contraction. Distributing the wound healing mechanisms to a broad surface allowed us to achieve better cosmetics without forming a noticeable scar on the chest wall. Keywords: Breast Ptosis, Extensive Liposuction, Gynecomastia Surgery, Ultrasonic Liposuction, Vaser Liposuction
目的：在胸壁上切除皮肤和腺体可能会留下明显的疤痕，患者难以忍受。本研究旨在确定一种无需手术切除妇科肿瘤的广泛超声波吸脂方法。我们还研究了该方法在减少并发症和改善美容效果方面的有效性。材料和方法：根据皮肤质量对罗氏 II 级和 III 级妇科整形患者进行评估。符合这些标准的 46 名患者在 2021 年 2 月至 2023 年 4 月期间接受了由资深作者实施的超声波吸脂术。这些患者与接受抽吸辅助吸脂术、乳晕周围乳房整形术和腺体切除术的 58 名患者进行了比较。研究结果我们的研究发现，接受广泛超声波吸脂术的患者并发症发生率为 8.7%。在所有患者中，只有一人出现血清肿并发症，三人出现乳房组织残留/凹陷。没有一名患者需要进行翻修手术。相比之下，接受乳晕周围乳房整形术和腺体切除术的对照组的并发症发生率更高（10.3%）。结论：我们利用整形外科的基本原则收缩伤口。将伤口愈合机制分布到广泛的表面，使我们能够获得更好的美容效果，而不会在胸壁上形成明显的疤痕。关键词乳房下垂、广泛吸脂、妇科整形、超声波吸脂、Vaser 吸脂术
{"title":"Extensive Ultrasonic Liposuction in Gynecomastia: An Alternative Approach without Surgical Gland Excision","authors":"A. Eyuboğlu","doi":"10.30733/std.2023.01699","DOIUrl":"https://doi.org/10.30733/std.2023.01699","url":null,"abstract":"Aim: Skin and gland removals made on the chest wall may result in noticeable scars that can be challenging for patients to tolerate. This \u0000study aimed to define an extensive ultrasonic liposuction approach without surgical excision for gynecomastia. We also investigated its \u0000effectiveness in reducing complications and improving cosmetic outcomes. \u0000Materials and Methods: Gynecomastia patients with Rohrich grades II and III were evaluated according to skin quality. 46 patients who \u0000met these criteria underwent ultrasonic liposuction performed by the senior author between February 2021 and April 2023. These patients \u0000were compared with 58 who underwent surgery using suction-assisted liposuction combined with peri areolar mastopexy and glandular \u0000excision. \u0000Results: Our study found that patients who underwent extensive ultrasonic liposuction had a complication rate of 8.7%. Of the total number \u0000of patients, only one experienced a seroma complication, and three experienced residual breast tissue/ptosis. None of the patients required \u0000revision surgery. In comparison, the control group that underwent peri-areolar mastopexy and glandular excision had a higher complication rate \u0000(10.3%). \u0000Conclusion: We used the basic principles of plastic surgery for wound contraction. Distributing the wound healing mechanisms to a broad \u0000surface allowed us to achieve better cosmetics without forming a noticeable scar on the chest wall. \u0000Keywords: Breast Ptosis, Extensive Liposuction, Gynecomastia Surgery, Ultrasonic Liposuction, Vaser Liposuction","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140380921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Selective Serotonin Reuptake Inhibitor (SSRI) group antidepressants are frequently used in heart patients. In the study, we aimed to investigate the effects of sertraline (SE) on aortic contraction on healthy/damaged rat aorta. Materials and Methods: Wistar albino rats (24) were divided into group1-aorta-intact endothelium and group2-aorta-damaged endothelium. The isolated aortic tissues were placed in organ baths. Changes in the isometric tension of the aortic rings were recorded. Contractions were recorded in both groups after the application of phenylephrine (PE 10-6M). Afterwards, cumulative sertraline (SE 50 mg) (10-9-10-4M) was given to group 1. In Group 2, to control aortic endothelial damage, acetylcholine (10-6M) was applied and the tissues were washed for an hour, the second dose of PE was given, then SE was given cumulatively (10-9-10-4M), and contractions were recorded. Results: After cumulative SE (10-9-10-4M) was given to Group 1, a significant inhibition in spontaneous contractions was detected in the first three sertraline doses (10-9,10-8,10-7)(p<0.05), and in the remaining sertraline doses contraction inhibition continued. When comparing SE 10 6,-5,-4 and 10-9,-8,-7 doses, there was inhibition of contractions (p<0.005). In group2, the inhibition of second PE contractions continued after sertraline doses, but the inhibition was observed less than in group1 (p<0.05). Conclusion: SE inhibited PE-induced smooth muscle contraction in rat isolated aorta. PE-induced smooth muscle contractions were inhibited more slowly in the endothelium-damaged aorta. It is thought that NO release and NO-dependent vasodilation in the aorta decrease as a result of damage. A clearer understanding of the effects of sertraline on the cardiovascular system will be possible with further research. Keywords: Aorta, endothelium, sertraline, contraction, vasorelaxation
目的：选择性羟色胺再摄取抑制剂（SSRI）类抗抑郁药常用于心脏病患者。本研究旨在探讨舍曲林（SE）对健康/受损大鼠主动脉收缩的影响。材料与方法将 24 只 Wistar 白化大鼠分为 1 组（主动脉内皮完整）和 2 组（主动脉内皮受损）。将离体主动脉组织置于器官浴中。记录主动脉环等长张力的变化。两组均在使用苯肾上腺素（PE 10-6M）后记录收缩。在第二组中，为控制主动脉内皮损伤，应用乙酰胆碱（10-6M）并清洗组织一小时后，给予第二剂 PE，然后累积给予 SE（10-9-10-4M）并记录收缩。结果第 1 组给予累积 SE（10-9-10-4M）后，前三个舍曲林剂量（10-9、10-8、10-7）对自发性收缩有显著抑制作用（P<0.05），其余舍曲林剂量对收缩的抑制作用仍在继续。比较 SE 106,-5,-4 和 10-9,-8,-7 剂量，收缩受到抑制（p<0.005）。在第 2 组中，舍曲林剂量后继续抑制第二次 PE 收缩，但观察到的抑制作用小于第 1 组（P<0.05）。结论SE可抑制PE诱导的大鼠离体主动脉平滑肌收缩。在内皮受损的大鼠主动脉中，PE 诱导的平滑肌收缩受到的抑制更慢。有观点认为，主动脉中 NO 的释放和 NO 依赖性血管舒张因损伤而减少。随着研究的深入，人们将有可能更清楚地了解舍曲林对心血管系统的影响。关键词主动脉 内皮细胞 舍曲林 收缩 血管舒张
{"title":"Does Sertraline Affect Contraction in Endothelium Damaged Aorta","authors":"Z. I. Solak Görmüş","doi":"10.30733/std.2023.01688","DOIUrl":"https://doi.org/10.30733/std.2023.01688","url":null,"abstract":"Aim: Selective Serotonin Reuptake Inhibitor (SSRI) group antidepressants are frequently used in heart patients. In the study, we aimed to \u0000investigate the effects of sertraline (SE) on aortic contraction on healthy/damaged rat aorta. \u0000Materials and Methods: Wistar albino rats (24) were divided into group1-aorta-intact endothelium and group2-aorta-damaged endothelium. The \u0000isolated aortic tissues were placed in organ baths. Changes in the isometric tension of the aortic rings were recorded. Contractions were recorded \u0000in both groups after the application of phenylephrine (PE 10-6M). Afterwards, cumulative sertraline (SE 50 mg) (10-9-10-4M) was given to group \u00001. In Group 2, to control aortic endothelial damage, acetylcholine (10-6M) was applied and the tissues were washed for an hour, the second dose\u0000 of PE was given, then SE was given cumulatively (10-9-10-4M), and contractions were recorded.\u0000 Results: After cumulative SE (10-9-10-4M) was given to Group 1, a significant inhibition in spontaneous contractions was detected in the first\u0000 three sertraline doses (10-9,10-8,10-7)(p<0.05), and in the remaining sertraline doses contraction inhibition continued. When comparing SE 10\u00006,-5,-4 and 10-9,-8,-7 doses, there was inhibition of contractions (p<0.005). In group2, the inhibition of second PE contractions continued after\u0000 sertraline doses, but the inhibition was observed less than in group1 (p<0.05).\u0000 Conclusion: SE inhibited PE-induced smooth muscle contraction in rat isolated aorta. PE-induced smooth muscle contractions were inhibited\u0000 more slowly in the endothelium-damaged aorta. It is thought that NO release and NO-dependent vasodilation in the aorta decrease as a result of\u0000 damage. A clearer understanding of the effects of sertraline on the cardiovascular system will be possible with further research.\u0000 Keywords: Aorta, endothelium, sertraline, contraction, vasorelaxation","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Probiotics are natural products with proven benefits in the prevention and treatment of many diseases, with relatively few side effects. The study aimed to assess medical students' knowledge, attitudes and usage habits about probiotics. Materials and Methods: This descriptive study comprised final-year medical students in the academic year 2019-2020. Preliminary information about the study was given to the participants, and their verbal consent was obtained. A questionnaire prepared by the researchers in line with the literature evaluating socio-demographic characteristics, probiotic food consumption and knowledge about probiotics was applied to the participants. Results: The mean age of 229 students (78.4%) who participated in the study was 24.24±1.61 years and 58.1% were female. Of the participants, 92.6% stated that they knew the term 'probiotic', 44.1% indicated that they knew the microorganism content of probiotic foods, and 54.2% did not consume probiotic-containing foods. The most common reasons for taking probiotics were 'digestive benefits' (42.4%) and 'boosting the immune system' (26.6%), while the most common reason for not taking probiotics was 'not needed'. In the study, 51.5% of students said they would recommend probiotic foods to their peers and patients, and the most common reason for recommendation was constipation (73.4%). The participants had a mean probiotic knowledge score of 52.41±8.70 (20-76) points. There was no relationship between male students' (51.34±9.05) and female students' knowledge levels (53.26±8.38) (p=0.101). Conclusion: The level of knowledge about probiotics, the consumption of probiotics and the attitude towards recommending probiotics among the Faculty of Medicine senior students were found to be moderate. Consumption of probiotics by healthy or sick people should be done on the advice of trained physicians Keywords: Probiotic, Medical Student, Knowledge, Attitude
{"title":"Evaluation of Attitudes and Knowledge Levels of Medical Faculty Students about Probiotics","authors":"F. Cihan","doi":"10.30733/std.2023.01690","DOIUrl":"https://doi.org/10.30733/std.2023.01690","url":null,"abstract":"Aim: Probiotics are natural products with proven benefits in the prevention and treatment of many diseases, with relatively few side effects. \u0000The study aimed to assess medical students' knowledge, attitudes and usage habits about probiotics.\u0000 Materials and Methods: This descriptive study comprised final-year medical students in the academic year 2019-2020. Preliminary information \u0000about the study was given to the participants, and their verbal consent was obtained. A questionnaire prepared by the researchers in line with \u0000the literature evaluating socio-demographic characteristics, probiotic food consumption and knowledge about probiotics was applied to the \u0000participants. \u0000Results: The mean age of 229 students (78.4%) who participated in the study was 24.24±1.61 years and 58.1% were female. Of the \u0000participants, 92.6% stated that they knew the term 'probiotic', 44.1% indicated that they knew the microorganism content of probiotic foods, \u0000and 54.2% did not consume probiotic-containing foods. The most common reasons for taking probiotics were 'digestive benefits' (42.4%) \u0000and 'boosting the immune system' (26.6%), while the most common reason for not taking probiotics was 'not needed'. In the study, 51.5% of \u0000students said they would recommend probiotic foods to their peers and patients, and the most common reason for recommendation was \u0000constipation (73.4%). The participants had a mean probiotic knowledge score of 52.41±8.70 (20-76) points. There was no relationship between \u0000male students' (51.34±9.05) and female students' knowledge levels (53.26±8.38) (p=0.101). \u0000Conclusion: The level of knowledge about probiotics, the consumption of probiotics and the attitude towards recommending probiotics among \u0000the Faculty of Medicine senior students were found to be moderate. Consumption of probiotics by healthy or sick people should be done on \u0000the advice of trained physicians\u0000 Keywords: Probiotic, Medical Student, Knowledge, Attitude","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140383033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The aim of this study was to evaluate the intra- and inter-rater reliability coefficients of the supraspinatus muscle thickness (SMT ), acromiohumeral distance (AHD), and coracohumeral distance (CHD) in patients with shoulder pain. Materials and Methods: This retrospective study included 80 patients who presented with complaints of shoulder pain at a single centre between January 2023 and January 2024. The supraspinatus muscle thickness, acromiohumeral distance, and coracohumeral distance measurements were obtained one week apart by two observers. The intraclass correlation coefficient (ICC), minimum detectable change, and standard error of measurement were subsequently calculated. Results: AHD intra-rater reliability results evaluated on coronal sections were excellent (Rater 1, ICC=0.96; 95% CI, 0.94-0.97; Rater 2 ICC=0.75; 95% CI, 0.61-0.84). AHD intra-rater reliability results evaluated on sagittal sections were excellent (Rater 1, ICC=0.94; 95% CI; 0.91-0.96; Rater 2 ICC=0.77; 95% CI, 0.64-0.85). The results of CHD measured using coronal sections were good (Rater 1, ICC=0.85; 95% CI, 0.76-0.90; Rater 2 ICC=0.82; 95% CI, 0.71-0.88). SMT measurement results measured using coronal sections were excellent (Rater 1, ICC=0.98; CI, 0.98-0.99; Rater 2, ICC=0.89; 95% CI, 0.82-0.93).The inter-rater reliability values were good for AHD-Coronal (ICC= 0.75; 95% CI, 0.61-0.84) and AHD-Sagittal (ICC=0.86; 95% CI, 0.79-0.91), were fair for CHD evaluated on coronal sections (ICC=0.74; %95 CI, 0.58-0.83), and were excellent for SMT evaluated on coronal sections (ICC=0.92; 95% CI, 0.87-0.95). Conclusion: These results suggest that magnetic resonance imaging measurements of the supraspinatus muscle thickness and acromiohumeral distance can be reliable and consistent for the clinical evaluation of patients with shoulder pain. Keywords: Reliability, shoulder measurement, magnetic resonance imaging
{"title":"Intra- and Inter-Rater Reliability of Magnetic Resonance Imaging Measurements of Supraspinatus Muscle Thickness, Acromiohumeral Distance, and Coracohumeral Distance in Patients with Shoulder Pain","authors":"B. Dede","doi":"10.30733/std.2023.01702","DOIUrl":"https://doi.org/10.30733/std.2023.01702","url":null,"abstract":"Aim: The aim of this study was to evaluate the intra- and inter-rater reliability coefficients of the supraspinatus muscle thickness (SMT ), \u0000acromiohumeral distance (AHD), and coracohumeral distance (CHD) in patients with shoulder pain. \u0000Materials and Methods: This retrospective study included 80 patients who presented with complaints of shoulder pain at a single centre \u0000between January 2023 and January 2024. The supraspinatus muscle thickness, acromiohumeral distance, and coracohumeral distance \u0000measurements were obtained one week apart by two observers. The intraclass correlation coefficient (ICC), minimum detectable change, and \u0000standard error of measurement were subsequently calculated. \u0000Results: AHD intra-rater reliability results evaluated on coronal sections were excellent (Rater 1, ICC=0.96; 95% CI, 0.94-0.97; Rater 2 ICC=0.75; \u000095% CI, 0.61-0.84). AHD intra-rater reliability results evaluated on sagittal sections were excellent (Rater 1, ICC=0.94; 95% CI; 0.91-0.96; Rater 2 \u0000ICC=0.77; 95% CI, 0.64-0.85). The results of CHD measured using coronal sections were good (Rater 1, ICC=0.85; 95% CI, 0.76-0.90; Rater 2 ICC=0.82; \u000095% CI, 0.71-0.88). SMT measurement results measured using coronal sections were excellent (Rater 1, ICC=0.98; CI, 0.98-0.99; Rater 2, ICC=0.89; \u000095% CI, 0.82-0.93).The inter-rater reliability values were good for AHD-Coronal (ICC= 0.75; 95% CI, 0.61-0.84) and AHD-Sagittal (ICC=0.86; 95% \u0000CI, 0.79-0.91), were fair for CHD evaluated on coronal sections (ICC=0.74; %95 CI, 0.58-0.83), and were excellent for SMT evaluated on \u0000coronal sections (ICC=0.92; 95% CI, 0.87-0.95). \u0000Conclusion: These results suggest that magnetic resonance imaging measurements of the supraspinatus muscle thickness and acromiohumeral \u0000distance can be reliable and consistent for the clinical evaluation of patients with shoulder pain. \u0000Keywords: Reliability, shoulder measurement, magnetic resonance imaging","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140385158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Multicentric reticulohistiocytosis (MRH) is a rare systemic proliferative granulomatous disease of non-Langerhans cells. The aim of this study is to report a case of multicentric reticulohistiocytosis that is easily misdiagnosed in clinical practice. A 74-year-old man sought the Rheumatology office in December 2022 with a main complaint of arthralgia for six months, associated with morning stiffness, joint swelling, and upper and lower limb weakness. On physical examination, papules on the dorsal surface of the proximal interphalangeal joints, base of the nose, and lateral surface of the right hallux were observed. Hyperemia was also identified on the back, and edema of the proximal and distal interphalangeal joints, wrists and knees. Laboratory tests revealed ESR and ANA within normal limits. Tests were negative for Anti-Sm, Anti-RO, rheumatoid factor, Anti-CCP, HIV, and HCV. Chest CT-scan showed right axillary lymph node enlargement, measuring 2.7 cm, atheromatous aorta, and streaks with scattered atelectasis in the lower lobe, without other changes. On total abdominal ultrasound, prostate enlargement was detected. Immunohistochemistry of skin biopsy identified atypical acinar proliferation. Histopathology skin biopsy stained with hematoxylin-eosin (January 2023) showed a dense histiocytic infiltrate. Detail of the histiocytic component displayed “ground glass” eosinophilic cytoplasm. Immunohistochemistry was negative for S100 and CD34 and positive for CD68. Final diagnosis was MRH. The patient underwent treatment with drugs. In conclusion, clinical manifestations, including skin and joint changes, with signs and symptoms of rheumatic disorders (e.g. dermatomyositis and rheumatoid arthritis) similar to those of MRH are expected in rheumatology practice. However, knowledge about disease progression in MRH is limited. Therefore, this case report is described due to its rarity Keywords: Non-Langerhans-Cell Histiocytosis, Pathology, Muticentric Reticulohistiocytosis, Rheumatological Diseases,
{"title":"A Rare Case of Multicentric Reticulohistiocytosis in An Elderly Male Patient","authors":"Rafael Everton Assunção Ribeiro da Costa","doi":"10.30733/std.2023.01716","DOIUrl":"https://doi.org/10.30733/std.2023.01716","url":null,"abstract":"Multicentric reticulohistiocytosis (MRH) is a rare systemic proliferative granulomatous disease of non-Langerhans cells. The aim of this study is \u0000to report a case of multicentric reticulohistiocytosis that is easily misdiagnosed in clinical practice. A 74-year-old man sought the Rheumatology \u0000office in December 2022 with a main complaint of arthralgia for six months, associated with morning stiffness, joint swelling, and upper and lower \u0000limb weakness. On physical examination, papules on the dorsal surface of the proximal interphalangeal joints, base of the nose, and lateral surface \u0000of the right hallux were observed. Hyperemia was also identified on the back, and edema of the proximal and distal interphalangeal joints, wrists \u0000and knees. Laboratory tests revealed ESR and ANA within normal limits. Tests were negative for Anti-Sm, Anti-RO, rheumatoid factor, Anti-CCP, \u0000HIV, and HCV. Chest CT-scan showed right axillary lymph node enlargement, measuring 2.7 cm, atheromatous aorta, and streaks with scattered \u0000atelectasis in the lower lobe, without other changes. On total abdominal ultrasound, prostate enlargement was detected. Immunohistochemistry \u0000of skin biopsy identified atypical acinar proliferation. Histopathology skin biopsy stained with hematoxylin-eosin (January 2023) showed a \u0000dense histiocytic infiltrate. Detail of the histiocytic component displayed “ground glass” eosinophilic cytoplasm. Immunohistochemistry was \u0000negative for S100 and CD34 and positive for CD68. Final diagnosis was MRH. The patient underwent treatment with drugs. In conclusion, clinical \u0000manifestations, including skin and joint changes, with signs and symptoms of rheumatic disorders (e.g. dermatomyositis and rheumatoid arthritis) \u0000similar to those of MRH are expected in rheumatology practice. However, knowledge about disease progression in MRH is limited. Therefore, this \u0000case report is described due to its rarity \u0000Keywords: Non-Langerhans-Cell Histiocytosis, Pathology, Muticentric Reticulohistiocytosis, Rheumatological Diseases,","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Although the etiopathogenesis of lichen planus is not clearly known, it has been noticed to be associated with various factors such as drugs, infections, autoimmune factors, genetic factors, and oxidative stress mechanisms. Oxidative stress is implicated in the pathogenesis of various diseases such as cancer and chronic inflammatory diseases. Complete blood count parameters can be utilized as oxidative stress diagnostic biomarkers for many diseases related to chronic inflammatory processes. In recent clinical studies, it has been shown that the monocyte/high-density lipoprotein (HDL) ratio (MHR) may be useful as a marker of oxidative stress in many chronic dermatoses. However, as far as we know, the relationship between oxidative stress and monocyte/HDL ratio in lichen planus cases has not been studied in the literature yet. Materials and Methods: The files of cases who were followed up with lichen planus in the dermatology clinic of a tertiary university hospital between February 2018 and July 2021 were reviewed retrospectively. There were 201 participants in the analysis, including 99 histopathologically and clinically verified LP cases and 102 age and sex-matched controls. Results: Monocyte values (p=0.16) and HDL levels (p=0.26) were not statistically different for both groups, but the MHR value (p=0.04) was detected to be statistically significantly higher in the lichen planus group than in the control group. In oral lichen planus cases, whilst the oral disease severity score and uric acid values were not correlated (p=0.11), the oral disease severity score was correlated with the CRP (p=0.03) and MHR (p=0.001) values. Conclusions: In the study, we found that MHR levels were significantly higher in lichen planus patients compared to the control group. Again, we detected that MHR had a better correlation with oral mucosa disease severity score than CRP. We suggest that MHR may be a potential index to assess disease activity in follow-up patients with lichen planus. Keywords: Lichen planus, oral mucosa, monocyte/high-density lipoprotein ratio
{"title":"Monocyte/High-Density Lipoprotein Ratio: An Indicator of Oxidative Stress and Disease Severity in Lichen Planus Patients","authors":"S. Temiz","doi":"10.30733/std.2023.01684","DOIUrl":"https://doi.org/10.30733/std.2023.01684","url":null,"abstract":"Aim: Although the etiopathogenesis of lichen planus is not clearly known, it has been noticed to be associated with various factors such as \u0000drugs, infections, autoimmune factors, genetic factors, and oxidative stress mechanisms. Oxidative stress is implicated in the pathogenesis of \u0000various diseases such as cancer and chronic inflammatory diseases. Complete blood count parameters can be utilized as oxidative stress \u0000diagnostic biomarkers for many diseases related to chronic inflammatory processes. In recent clinical studies, it has been shown that the \u0000monocyte/high-density lipoprotein (HDL) ratio (MHR) may be useful as a marker of oxidative stress in many chronic dermatoses. However, as far \u0000as we know, the relationship between oxidative stress and monocyte/HDL ratio in lichen planus cases has not been studied in the literature yet.\u0000 Materials and Methods: The files of cases who were followed up with lichen planus in the dermatology clinic of a tertiary university \u0000hospital between February 2018 and July 2021 were reviewed retrospectively. There were 201 participants in the analysis, including 99 \u0000histopathologically and clinically verified LP cases and 102 age and sex-matched controls.\u0000 Results: Monocyte values (p=0.16) and HDL levels (p=0.26) were not statistically different for both groups, but the MHR value (p=0.04) \u0000was detected to be statistically significantly higher in the lichen planus group than in the control group. In oral lichen planus cases, whilst \u0000the oral disease severity score and uric acid values were not correlated (p=0.11), the oral disease severity score was correlated with the CRP \u0000(p=0.03) and MHR (p=0.001) values.\u0000 Conclusions: In the study, we found that MHR levels were significantly higher in lichen planus patients compared to the control group. Again, \u0000we detected that MHR had a better correlation with oral mucosa disease severity score than CRP. We suggest that MHR may be a potential \u0000index to assess disease activity in follow-up patients with lichen planus.\u0000 Keywords: Lichen planus, oral mucosa, monocyte/high-density lipoprotein ratio","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Early diagnosis and timely care is important in patients with Developmental Hip Dysplasia (DDH). Late presenting or neglected patients may require various osteotomy procedures. There is a limited number of articles in the literature on Pembersal osteotomy in DDH surgery. The aim of this study was to assess the outcomes of isolated Pembersal osteotomy in children over 18 months of age with DDH. Materials and Methods: A retrospective analysis was made of the outcomes of patients who underwent Pembersal osteotomy for DDH at our clinic from 2014 to 2021. The study included 9 children (7 girls, 2 boys) aged between 19 and 36 months with at least 2 years of follow-up who underwent isolated periacetabular Pembersal osteotomy with open reduction. Preoperative, early postoperative, 6 weeks postoperative and final follow-up radiographs were evaluated and Wiberg's centre-edge angle (CEA), the acetabular index (AI) and Tönnis grades were noted. Results: The mean age of the patients was 28.75 months and the follow-up period was 50.33 months. CEA and AI showed improvement in the early postoperative period and this improvement continued in the later periods. Tönnis staging showed postoperative improvement in all patients, and this improvement continued in the early postoperative period and on the 6-week follow-up radiographs. At the final follow-up examination, 3 hips had CEA <20º, AI >20º and Tönnis stage ≥2 and these 3 hips were considered as a radiologically poor outcome. Conclusion: This study demonstrated that isolated Pembersal osteotomy is an effective and safe option for the treatment of developmental dysplasia of the hip, with improvement in acetabular index and other radiological parameters. Keywords: Developmental dysplasia of the hip, periacetabular osteotomy, Pembersal osteotomy, centre-edge angle, acetabular index
{"title":"Early And Mid-Term Radiological Results of Isolated Pembersal Procedure in Cases of Developmental Dislocation of The Hip","authors":"A. Baymurat","doi":"10.30733/std.2023.01696","DOIUrl":"https://doi.org/10.30733/std.2023.01696","url":null,"abstract":"Aim: Early diagnosis and timely care is important in patients with Developmental Hip Dysplasia (DDH). Late presenting or neglected patients may \u0000require various osteotomy procedures. There is a limited number of articles in the literature on Pembersal osteotomy in DDH surgery. The aim of \u0000this study was to assess the outcomes of isolated Pembersal osteotomy in children over 18 months of age with DDH.\u0000 Materials and Methods: A retrospective analysis was made of the outcomes of patients who underwent Pembersal osteotomy for DDH at our \u0000clinic from 2014 to 2021. The study included 9 children (7 girls, 2 boys) aged between 19 and 36 months with at least 2 years of follow-up who \u0000underwent isolated periacetabular Pembersal osteotomy with open reduction. Preoperative, early postoperative, 6 weeks postoperative and final \u0000follow-up radiographs were evaluated and Wiberg's centre-edge angle (CEA), the acetabular index (AI) and Tönnis grades were noted. \u0000Results: The mean age of the patients was 28.75 months and the follow-up period was 50.33 months. CEA and AI showed improvement in the early \u0000postoperative period and this improvement continued in the later periods. Tönnis staging showed postoperative improvement in all patients, and \u0000this improvement continued in the early postoperative period and on the 6-week follow-up radiographs. At the final follow-up examination, 3 \u0000hips had CEA <20º, AI >20º and Tönnis stage ≥2 and these 3 hips were considered as a radiologically poor outcome. \u0000Conclusion: This study demonstrated that isolated Pembersal osteotomy is an effective and safe option for the treatment of developmental \u0000dysplasia of the hip, with improvement in acetabular index and other radiological parameters.\u0000 Keywords: Developmental dysplasia of the hip, periacetabular osteotomy, Pembersal osteotomy, centre-edge angle, acetabular index","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hematological Involvement in Sjögren s Syndrome and The Relationship of Involvement with Salivary Gland Biopsy","authors":"Mustafa Çağrı Ergun","doi":"10.30733/std.2023.01636","DOIUrl":"https://doi.org/10.30733/std.2023.01636","url":null,"abstract":"<jats:p xml:lang=\"tr\" />","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138995941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient Management and Surgical Results in Osteocondroma Cases","authors":"Mehmet Akif Şimşek","doi":"10.30733/std.2023.01679","DOIUrl":"https://doi.org/10.30733/std.2023.01679","url":null,"abstract":"<jats:p xml:lang=\"tr\" />","PeriodicalId":332557,"journal":{"name":"Selcuk Tip Dergisi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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