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Antenatal prediction of small for gestational age at birth based on four birthweight standards using machine learning algorithms. 基于四种出生体重标准,使用机器学习算法预测出生时胎龄小。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1679979
Qiu-Yan Yu, Ying Lin, Yu-Run Zhou, Xin-Jun Yang, Joris Hemelaar

Background: Accurate antenatal prediction of SGA at birth is essential to improve development and delivery of preventative and therapeutic interventions. This study aimed to assess the performance of machine learning (ML) models to predict SGA at birth among Chinese pregnancies classified according to the Chinese birthweight standard and three international birthweight standards.

Methods: We collected multimodal, longitudinal, antenatal surveillance data on 350,135 singleton pregnancies in Wenzhou City, China, between Jan 1, 2014 and Dec 31, 2016. For three pregnancy intervals we developed ML prediction models for newborns classified as SGA using the China, Intergrowth 21st, Fetal Medicine Foundation (FMF), and Gestation-related Optimal Weight (GROW) standards. We applied lasso regression to conduct feature selection, and CatBoost, XGBoost, LightBoost, Artificial Neural Networks, Random Forest, Stacked ensemble model, and logistic regression for predictive modeling in training data sets, with validation in testing data sets.

Results: Among 22,603 singleton pregnancies with complete data, the rate of SGA using the China standard was 6.1%, compared to 4.3, 6.0, and 9.7% for the Intergrowth 21st, GROW, and FMF standards, respectively. This pattern was maintained in the imputed data set (n = 225,523), with corresponding SGA rates of 6.8, 4.8, 7.4, and 10.7%. Late pregnancy models (<37 weeks) had the best power to predict SGA, compared to middle (<26 weeks) and early pregnancy (<18 weeks) models. With the China standard, the logistic regression model in late pregnancy performed best with an area under the receiver operating characteristic curve (ROC-AUC) of 0.74. Logistic regression also performed better than ML algorithms with the Intergrowth-21st and GROW standards at each pregnancy interval, although differences were small. The Random Forest model with the FMF standard achieved superior performance at each pregnancy interval, reaching a ROC-AUC of 0.79 in late pregnancy. Notably, the middle pregnancy Random Forest model with the FMF standard already attained a ROC-AUC of 0.72 at 26 weeks' gestation. Symphysis-fundal height, maternal abdominal circumference, maternal age, maternal height and weight, and parity were consistently identified as key predictors of SGA across the different standards.

Conclusion: There are important differences in the classification of SGA at birth between national and international birthweight standards. Both machine learning models and traditional logistic regression demonstrated comparable predictive performance for SGA identification. These findings hold promise for guiding risk-stratified prenatal care and optimizing resource allocation in clinical settings.

背景:出生时准确的SGA产前预测对于改善预防和治疗干预措施的制定和实施至关重要。本研究旨在评估机器学习(ML)模型在根据中国出生体重标准和三个国际出生体重标准分类的中国孕妇中预测出生时SGA的性能。方法:收集2014年1月1日至2016年12月31日中国温州市350135例单胎妊娠的多模式、纵向、产前监测数据。对于三个妊娠期,我们使用中国、Intergrowth 21、胎儿医学基金会(FMF)和妊娠相关最佳体重(GROW)标准建立了被分类为SGA的新生儿ML预测模型。我们使用lasso回归进行特征选择,使用CatBoost、XGBoost、LightBoost、人工神经网络、随机森林、堆叠集成模型和逻辑回归在训练数据集中进行预测建模,并在测试数据集中进行验证。结果:在22,603例数据完整的单胎妊娠中,使用中国标准的SGA率为6.1%,而使用Intergrowth 21、GROW和FMF标准的SGA率分别为4.3%、6.0和9.7%。这种模式在输入的数据集中保持不变(n = 225,523),相应的SGA率分别为6.8,4.8,7.4和10.7%。结论:国内与国际出生体重标准对出生时SGA的分类存在重要差异。机器学习模型和传统逻辑回归对SGA识别的预测性能相当。这些发现为指导风险分层产前护理和优化临床资源分配提供了希望。
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引用次数: 0
PotatoLeafNet: two-stage convolutional neural networks for effective Potato Leaf disease identification and classification. PotatoLeafNet:用于马铃薯叶病识别和分类的两阶段卷积神经网络。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1668839
Girigula Durga Bhavani, Mukkoti Maruthi Venkata Chalapathi

Introduction: Potato foliar diseases, particularly early and late blight, pose a serious threat to yield and food security, yet reliable visual recognition remains challenging due to cultivar heterogeneity, variable symptom expression, and acquisition noise in field-like imagery. To address these issues, we propose PotatoLeafNet, a two-stage deep learning framework that combines a fixed-sequence image-augmentation pipeline with a compact, task-optimized 11-layer convolutional neural network (CNN) using 3 × 3 kernels for robust, data-efficient classification of potato leaf conditions (Healthy, Early Blight, Late Blight).

Methods: We construct a dataset of 4,072 labeled potato leaf images from the PlantVillage-Potato subset and standardize all inputs to 224 × 224 RGB tensors with pixel intensities normalized to [0,1]. A balanced, fixed-order augmentation policy-comprising rotation, translation, shear, zoom, horizontal flipping, brightness adjustment, and channel jitter-is applied exclusively to the training split, increasing it to 6,000 images (2,000 per class) while keeping the validation and test sets free of synthetic samples. The second stage consists of an 11-layer CNN implemented in TensorFlow/Keras and trained with categorical cross-entropy loss and the Adam optimizer under a unified training and evaluation protocol. Performance is benchmarked against strong CNN and hybrid baselines, including ResNet-50 + VGG-16, VGG-16 + MobileNetV2, MobileNetV2, and Inception-V3.

Results: On the PlantVillage-Potato test set, PotatoLeafNet achieves 98.52% accuracy, 98.67% macro-precision, 99.67% macro-recall, 99.16% macro-F1, and 1.00 macro-AUC, outperforming all baseline models under identical preprocessing and training conditions. In particular, PotatoLeafNet surpasses ResNet-50 + VGG-16 (97.10% accuracy, AUC 0.98), VGG-16 + MobileNetV2 (94.80% accuracy, AUC 0.93), MobileNetV2 (93.20% accuracy, AUC 0.92), and Inception-V3 (92.50% accuracy, AUC 0.91). Short 10-epoch runs yield stable convergence (training accuracy 88.22%, validation accuracy 86.91%, test accuracy 88.15%), indicating efficient learning from the augmented distribution.

Discussion: The results demonstrate that explicitly coupling a fixed sequential augmentation stage with a lightweight 3×3-kernel CNN enables high tri-class accuracy, strong recall for disease classes, and improved generalization relative to deeper or fused architectures, without incurring substantial computational cost. By emphasizing disease-relevant structure while limiting overfitting, PotatoLeafNet provides a practical and resource-efficient solution for automated screening of potato leaf health in real-world agronomic settings, supporting timely and data-driven disease management.

马铃薯叶面病害,特别是早疫病和晚疫病,对产量和粮食安全构成严重威胁,但由于品种异质性、症状表达变量和田样图像中的采集噪声,可靠的视觉识别仍然具有挑战性。为了解决这些问题,我们提出了PotatoLeafNet,这是一个两阶段的深度学习框架,将固定序列图像增强管道与紧凑的任务优化的11层卷积神经网络(CNN)结合在一起,使用3个 × 3个内核对马铃薯叶片状况(健康、早疫病、晚疫病)进行鲁棒、数据高效的分类。方法:我们从PlantVillage-Potato子集中构建了一个包含4072张带标签的马铃薯叶片图像的数据集,并将所有输入标准化为224张 × 224张RGB张量,像素强度归一化为[0,1]。平衡的、固定顺序的增强策略(包括旋转、平移、剪切、缩放、水平翻转、亮度调整和通道抖动)专门应用于训练分割,将其增加到6,000个图像(每个类2,000个),同时保持验证和测试集不受合成样本的影响。第二阶段包括在TensorFlow/Keras中实现的11层CNN,并在统一的训练和评估协议下使用分类交叉熵损失和Adam优化器进行训练。性能以强大的CNN和混合基线为基准,包括ResNet-50 + VGG-16, VGG-16 + MobileNetV2, MobileNetV2和Inception-V3。结果:在PlantVillage-Potato测试集上,PotatoLeafNet的准确率达到98.52%,宏观精度达到98.67%,宏观召回率达到99.67%,宏观f1达到99.16%,宏观auc达到1.00,优于相同预处理和训练条件下的所有基线模型。特别是,PotatoLeafNet超过ResNet-50 + VGG-16(97.10%准确率,AUC 0.98), VGG-16 + MobileNetV2(94.80%准确率,AUC 0.93), MobileNetV2(93.20%准确率,AUC 0.92)和Inception-V3(92.50%准确率,AUC 0.91)。短时间的10 epoch运行产生稳定的收敛(训练准确率88.22%,验证准确率86.91%,测试准确率88.15%),表明从增强分布中有效学习。讨论:结果表明,将固定的顺序增强阶段与轻量级3×3-kernel CNN显式耦合可以实现高三类精度,对疾病类别的强召回,以及相对于更深或融合架构的改进泛化,而不会产生大量的计算成本。通过强调与疾病相关的结构,同时限制过拟合,PotatoLeafNet为实际农艺环境中马铃薯叶片健康的自动筛选提供了实用且资源高效的解决方案,支持及时和数据驱动的疾病管理。
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引用次数: 0
Adaptive low-light image enhancement using Interval-Valued Intuitionistic Fuzzy Set optimized by Reptile Search Algorithm. 爬行动物搜索算法优化的区间值直觉模糊集自适应弱光图像增强。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1721291
Haripriya Yogambaram, M Sivabalakrishnan, S Balaji

Superiority of images in low light is necessary in the case of medical image as well as autonomous systems but there is still a challenge of balancing between brightness and natural appearance. The presented paper elaborates a new improvement model that combines Interval-Valued Intuitionistic Fuzzy Set as well as Reptile Search Algorithm optimization. The proposed approach automatically tunes the fuzzy membership and hesitation factors to adapt to uncertainty in dark areas while preserving significant structural data. The Performance is evaluated using common objective metrics which are Peak Signal-to-Noise Ratio, Absolute Mean Brightness Error, Contrast Improvement Index and entropy. All the reported percentage improvements are computed using the average metric values of the baseline Interval-Valued Intuitionistic Fuzzy Set method on the complete dataset. The results of the investigations indicate significant and consistent increases in the experimental results with a 3.69% percentage gain in entropy, a 21.71% percentage gain in brightness restoration, an 18.73% percentage gain in contrast and a 66.12% percentage gain in Peak Signal to Noise Ratio compared to the baseline method. As these results show, the given technique yields naturally amplified images that have better qualities in clarity, conciseness and structural conservation, which is extremely applicable in real-life situations involving low-light photography.

对于医学图像和自主系统来说,低光下的图像优势是必要的,但在亮度和自然外观之间的平衡仍然是一个挑战。本文阐述了一种结合区间值直觉模糊集和爬行动物搜索算法优化的改进模型。该方法在保留重要结构数据的同时,自动调整模糊隶属度和犹豫因子,以适应暗区的不确定性。使用峰值信噪比、绝对平均亮度误差、对比度改进指数和熵等常见客观指标对性能进行评估。所有报告的百分比改进都是使用完整数据集上基线区间值直觉模糊集方法的平均度量值计算的。研究结果表明,与基线方法相比,熵增加3.69%,亮度恢复21.71%,对比度增加18.73%,峰值信噪比增加66.12%,实验结果显著提高。正如这些结果所表明的那样,给定的技术产生的自然放大图像在清晰度、简洁性和结构保存方面具有更好的质量,这非常适用于现实生活中涉及弱光摄影的情况。
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引用次数: 0
Smart manufacturing-driven probabilistic process planning for components via AP-BiLSTM-ATT. 基于AP-BiLSTM-ATT的智能制造驱动组件概率工艺规划。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1745372
Wei Yang, Jinyan Liang, Xiaoyu Zhang, Xiting Peng

In the context of smart manufacturing, improving the quality and efficiency of process planning, especially in the processing of complex parts, has become a key factor influencing the level of intelligence in manufacturing systems. However, most current process planning methods still heavily rely on manual expertise, leading to problems such as difficulty in knowledge reuse, low planning efficiency, and slow response times, which are inadequate to meet the diverse and changing needs of engineering applications. To address these issues, this paper proposes an algorithm for Assembly Process Reasoning and Decision-making based on Bidirectional Long Short-Term Memory with Attention (AP-BiLSTM-ATT), which aims to deeply explore the hidden relationships between the multi-dimensional features of parts and process plans, thereby achieving probabilistic modeling of process decisions. Specifically, the attributes, geometric features, and historical process plans of parts are first labeled and vectorized, transforming traditional process knowledge into structured data representations suitable for deep learning models. A BiLSTM network model, integrated with a multi-head attention mechanism, is then constructed to capture contextual dependencies and semantic weight distributions between features, enhancing the model's ability to express complex process relationships. During training, the model learns the mapping distribution between features and processes from a large-scale historical process dataset, enabling intelligent reasoning and recommendation of process plans for new parts. The results show that this method outperforms traditional methods in terms of accuracy, response speed, and generalization ability in process planning, providing effective support for enhancing the intelligence of complex part process planning and laying a foundation for the structured expression and intelligent application of manufacturing process knowledge.

在智能制造的背景下,提高工艺规划的质量和效率,特别是复杂零件加工的质量和效率,已成为影响制造系统智能化水平的关键因素。然而,目前大多数工艺规划方法仍然严重依赖人工专业知识,存在知识重用困难、规划效率低、响应速度慢等问题,无法满足工程应用多样化和不断变化的需求。针对这些问题,本文提出了一种基于注意双向长短期记忆的装配过程推理与决策算法(AP-BiLSTM-ATT),该算法旨在深入挖掘零件的多维特征与工艺方案之间的隐藏关系,从而实现工艺决策的概率建模。具体而言,首先对零件的属性、几何特征和历史工艺方案进行标记和矢量化,将传统的工艺知识转化为适合深度学习模型的结构化数据表示。结合多头注意机制构建BiLSTM网络模型,捕捉特征之间的上下文依赖关系和语义权重分布,增强模型表达复杂过程关系的能力。在训练过程中,模型从大规模历史过程数据集中学习特征和过程之间的映射分布,实现新零件的智能推理和工艺方案推荐。结果表明,该方法在工艺规划精度、响应速度、泛化能力等方面均优于传统方法,为提高复杂零件工艺规划的智能化提供了有效支持,为制造工艺知识的结构化表达和智能化应用奠定了基础。
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引用次数: 0
Beyond mimicry: a framework for evaluating genuine intelligence in artificial systems. 超越模仿:评估人工系统中真正智能的框架。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1686752
Sarfaraz K Niazi

Current AI benchmarks often equate mimicry with genuine intelligence, emphasizing task performance over the underlying cognitive processes that enable human-like understanding. The Machine Perturbational Complexity & Agency Battery (mPCAB) introduces a new, substrate-independent framework that applies neurophysiological methods used initially to assess consciousness in artificial systems. Unlike existing evaluations, it features four key components-perturbational complexity, global workspace assessment, norm internalization, and agency-that link mechanisms with functions. This enables systematic comparisons across digital, neuromorphic, and biological substrates, addressing three research gaps: long-term reasoning with coherent behavior, norm internalization amid distribution shifts, and transformational creativity involving meta-cognitive rule modification. By analyzing theories of consciousness (GNW, IIT, PP, HOT), we identify targets for AI implementation. Our cognitive architecture analysis maps human functions-such as working memory and executive control-to their computational counterparts, providing guiding principles for design. The creativity taxonomy progresses from combinational to transformational, with measurable criteria like changes in conceptual space and the depth of meta-level reasoning. Ethical considerations are integrated into frameworks for monitoring organoid intelligence, reducing bias in creativity, and addressing rights issues. Pilot studies demonstrate mPCAB's feasibility across different substrates and show that its metrics are comparable. This framework moves evaluation away from superficial benchmarks toward mechanism-based assessment, supporting the development of mind-like machines and responsible AI advancements.

目前的人工智能基准通常将模仿等同于真正的智能,强调任务表现,而不是实现类似人类理解的潜在认知过程。机器摄动复杂性和机构电池(mPCAB)引入了一种新的、与基质无关的框架,该框架应用了最初用于评估人工系统意识的神经生理学方法。与现有的评估不同,它具有四个关键组成部分——扰动复杂性、全局工作空间评估、规范内部化和代理——将机制与功能联系起来。这使得数字、神经形态和生物基质之间的系统比较成为可能,解决了三个研究空白:具有连贯行为的长期推理,分布变化中的规范内化,以及涉及元认知规则修改的转型创造力。通过分析意识理论(GNW, IIT, PP, HOT),我们确定了人工智能实施的目标。我们的认知架构分析将人类的功能——比如工作记忆和执行控制——映射到它们的计算对应部分,为设计提供指导原则。创造力分类法从组合到转换,具有可测量的标准,如概念空间的变化和元层次推理的深度。伦理考虑被纳入了监测类器官智能、减少创造力偏见和解决权利问题的框架。试点研究证明了mPCAB在不同基材上的可行性,并表明其指标具有可比性。该框架将评估从肤浅的基准转向基于机制的评估,支持类思维机器的开发和负责任的人工智能进步。
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引用次数: 0
Deep learning and machine learning integration of radiomics and transcriptomics predicts response-adapted radiotherapy outcome and radiosensitivity in resectable locally advanced laryngeal carcinoma. 放射组学和转录组学的深度学习和机器学习集成预测可切除的局部晚期喉癌的反应适应放射治疗结果和放射敏感性。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1738174
Shafat Ujjahan, Abu Shadat M Noman, Sarah S Al-Johani, Zakia Shinwari, Ayodele A Alaiya, Syed S Islam
<p><strong>Background: </strong>Radiotherapy (RT) remains a cornerstone treatment for head and neck cancer squamous cell carcinoma. However, therapeutic responses vary considerably among patients due to radiation resistance, which limits long-term survival and contributes to recurrence and disease progression. Developing robust deep learning (DL) and machine learning (ML)-based predictive models is essential to improve response prediction, evaluate treatment outcomes, and identify biomarkers linked to radiosensitization.</p><p><strong>Methods: </strong>This single-center retrospective study applied DL and ML models to analyze CT scans and RNA-seq gene expression data for prognostic and biomarker discovery purposes. For image analyses, two independent datasets were used. Dataset A includes 1,100 CT scans (pre- and post-treatment) from 476 patients with stage III and IV laryngeal carcinoma treated with response-adapted RT. A convolutional neural network (CNNs) integrated with a recurrent network (RNNs) was used for single-point tumor localization and response prediction. Dataset B, comprising 500 scans from 169 patients treated with radical RT, served as the additional validation cohort. Pre- and post-treatment scans were used to train a DL model, which showed better prediction performance for survival and disease-specific outcomes, including progression and locoregional recurrence. For gene expression-based biomarker analysis, TCGA data (<i>n</i> = 231) were examined using glmBoost, support vector machine classifier (SVM), and random forest (RF) algorithms to construct and predict genes associated with radiosensitivity, and the GSE20020 dataset was used to validate the model performance. Proteins and mRNA were used to confirm the signature biomarkers using qRT-PCR and LC-MS mass spectrometry.</p><p><strong>Findings: </strong>For CT scan image analysis, the DL-model achieved AUCs of 0.792 (<i>p</i> = 0.031) at 2-month and 0.832 (<i>p</i> < 0.01) at 6-month follow-up. Risk scores significantly correlated with overall survival (HR 1.59, 95% CI 1.34-3.22, <i>p</i> = 0.063), progression-free survival (1.39, 95% CI 1.16-2.29, <i>p</i> = 0.103). The pathological response in dataset B was likewise significantly predicted by the model. Among 39 differentially expressed genes, ML-model analysis identified 13 candidate genes associated with radiosensitivity on repeated cross-validation with an AUROC of 0.91 in the training set. In the validation dataset, when the models were optimized, the models consistently predicted seven core genes, achieving AUCs ranging from 0.96 to 0.94 to predict the radiosensitivity.</p><p><strong>Interpretation: </strong>These findings highlight the effectiveness of DL and ML approaches in integrating imaging and transcriptomic data to predict response-adapted RT response and patient outcomes. These automated, and interpretable AI-driven biomarkers hold significant potential for clinical translation. Future research should aim to e
背景:放疗(RT)仍然是头颈癌鳞状细胞癌的基础治疗方法。然而,由于放射耐药,患者之间的治疗反应差异很大,这限制了长期生存并导致复发和疾病进展。开发强大的基于深度学习(DL)和机器学习(ML)的预测模型对于改善反应预测、评估治疗结果和识别与放射致敏相关的生物标志物至关重要。方法:这项单中心回顾性研究应用DL和ML模型分析CT扫描和RNA-seq基因表达数据,以发现预后和生物标志物。对于图像分析,使用了两个独立的数据集。数据集A包括476例接受反应性rt治疗的III期和IV期喉癌患者的1100次CT扫描(治疗前和治疗后)。卷积神经网络(cnn)与复发性网络(rnn)相结合用于单点肿瘤定位和反应预测。数据集B包括来自169名接受根治性放疗的患者的500次扫描,作为额外的验证队列。治疗前和治疗后扫描用于训练DL模型,该模型对生存和疾病特异性结果(包括进展和局部复发)显示出更好的预测性能。对于基于基因表达的生物标志物分析,使用glmBoost、支持向量机分类器(SVM)和随机森林(RF)算法对TCGA数据(n = 231)进行检查,构建和预测与放射敏感性相关的基因,并使用GSE20020数据集验证模型的性能。采用qRT-PCR和LC-MS质谱法对蛋白质和mRNA进行鉴定。结果:对于CT扫描图像分析,dl模型在2个月时的auc为0.792 (p = 0.031),0.832 (p p = 0.063),无进展生存期(1.39,95% CI 1.16-2.29, p = 0.103)。数据集B中的病理反应同样被该模型显著预测。在39个差异表达基因中,ml模型分析通过反复交叉验证确定了13个与放射敏感性相关的候选基因,训练集中的AUROC为0.91。在验证数据集中,优化模型后,模型对7个核心基因的预测一致,auc范围为0.96 ~ 0.94。解释:这些发现强调了DL和ML方法在整合成像和转录组学数据以预测反应适应的RT反应和患者结果方面的有效性。这些自动化的、可解释的人工智能驱动的生物标志物在临床翻译方面具有巨大的潜力。未来的研究应旨在扩大数据集,并在多中心队列中验证模型,以获得更广泛的适用性。
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引用次数: 0
The collaborations among healthcare systems, research institutions, and industry on artificial intelligence research and development. 医疗保健系统、研究机构和产业界在人工智能研发方面的合作。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1694145
Jiancheng Ye, Michelle Ma, Malak Abuhashish

Objectives: The integration of Artificial Intelligence (AI) in healthcare promises to revolutionize patient care, diagnostics, and treatment protocols. Collaborative efforts among healthcare systems, research institutions, and industry are pivotal to leveraging AI's full potential. Understanding these dynamics is essential for addressing current challenges and shaping future AI development in healthcare. This study aims to characterize collaborative networks and stakeholders in AI healthcare initiatives, identify challenges and opportunities within these collaborations, and elucidate priorities for future AI research and development.

Methods: This study analyzed publicly available survey data previously collected by the Chinese Society of Radiology and the Chinese Medical Imaging AI Innovation Alliance. We performed secondary analysis of the national cross-sectional survey that was conducted in China with a total of 5,262 participants (5,142 clinicians and 120 research institution professionals), involving participants from three key groups: clinicians, institution professionals, and industry representatives. The survey explored diverse aspects including current AI usage in healthcare, collaboration dynamics, challenges encountered, and research and development priorities.

Results: Findings reveal high interest in AI among clinicians, with a significant gap between interest and actual engagement in development activities. Key findings include limited establishment of AI research departments and scarce interdisciplinary collaborations. Despite the willingness to share data, progress is hindered by concerns about data privacy and security, and lack of clear industry standards and legal guidelines. Future development interests focus on lesion screening, disease diagnosis, and enhancing clinical workflows.

Conclusion: This study highlights an enthusiastic yet cautious approach toward AI in healthcare, characterized by significant barriers that impede effective collaboration and implementation. Recommendations emphasize the need for AI-specific education and training, secure data-sharing frameworks, establishment of clear industry standards, and formation of dedicated AI research departments.

目标:人工智能(AI)在医疗保健领域的整合有望彻底改变患者护理、诊断和治疗方案。医疗保健系统、研究机构和行业之间的协作努力对于充分利用人工智能的潜力至关重要。了解这些动态对于应对当前挑战和塑造医疗保健领域未来的人工智能发展至关重要。本研究旨在描述人工智能医疗保健计划中的协作网络和利益相关者,确定这些合作中的挑战和机遇,并阐明未来人工智能研究和开发的优先事项。方法:本研究分析了中国放射学会和中国医学成像人工智能创新联盟之前收集的公开调查数据。我们对在中国进行的全国横断面调查进行了二次分析,共有5262名参与者(5142名临床医生和120名研究机构专业人员),参与者来自三个关键群体:临床医生、机构专业人员和行业代表。该调查探讨了多个方面,包括当前人工智能在医疗保健领域的使用、协作动态、遇到的挑战以及研发优先事项。结果:研究结果显示,临床医生对人工智能的兴趣很高,但在兴趣和实际参与开发活动之间存在显著差距。主要发现包括人工智能研究部门的建立有限,跨学科合作稀缺。尽管有共享数据的意愿,但对数据隐私和安全的担忧,以及缺乏明确的行业标准和法律指导方针,阻碍了进展。未来的发展重点是病变筛查、疾病诊断和增强临床工作流程。结论:本研究强调了对医疗保健领域人工智能的热情而谨慎的态度,其特点是阻碍有效合作和实施的重大障碍。建议强调需要针对人工智能的教育和培训,安全的数据共享框架,建立明确的行业标准,以及组建专门的人工智能研究部门。
{"title":"The collaborations among healthcare systems, research institutions, and industry on artificial intelligence research and development.","authors":"Jiancheng Ye, Michelle Ma, Malak Abuhashish","doi":"10.3389/frai.2025.1694145","DOIUrl":"10.3389/frai.2025.1694145","url":null,"abstract":"<p><strong>Objectives: </strong>The integration of Artificial Intelligence (AI) in healthcare promises to revolutionize patient care, diagnostics, and treatment protocols. Collaborative efforts among healthcare systems, research institutions, and industry are pivotal to leveraging AI's full potential. Understanding these dynamics is essential for addressing current challenges and shaping future AI development in healthcare. This study aims to characterize collaborative networks and stakeholders in AI healthcare initiatives, identify challenges and opportunities within these collaborations, and elucidate priorities for future AI research and development.</p><p><strong>Methods: </strong>This study analyzed publicly available survey data previously collected by the Chinese Society of Radiology and the Chinese Medical Imaging AI Innovation Alliance. We performed secondary analysis of the national cross-sectional survey that was conducted in China with a total of 5,262 participants (5,142 clinicians and 120 research institution professionals), involving participants from three key groups: clinicians, institution professionals, and industry representatives. The survey explored diverse aspects including current AI usage in healthcare, collaboration dynamics, challenges encountered, and research and development priorities.</p><p><strong>Results: </strong>Findings reveal high interest in AI among clinicians, with a significant gap between interest and actual engagement in development activities. Key findings include limited establishment of AI research departments and scarce interdisciplinary collaborations. Despite the willingness to share data, progress is hindered by concerns about data privacy and security, and lack of clear industry standards and legal guidelines. Future development interests focus on lesion screening, disease diagnosis, and enhancing clinical workflows.</p><p><strong>Conclusion: </strong>This study highlights an enthusiastic yet cautious approach toward AI in healthcare, characterized by significant barriers that impede effective collaboration and implementation. Recommendations emphasize the need for AI-specific education and training, secure data-sharing frameworks, establishment of clear industry standards, and formation of dedicated AI research departments.</p>","PeriodicalId":33315,"journal":{"name":"Frontiers in Artificial Intelligence","volume":"8 ","pages":"1694145"},"PeriodicalIF":4.7,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12832655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146067347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health state prediction with reinforcement learning for predictive maintenance. 使用用于预测性维护的强化学习进行健康状态预测。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1720140
Anastasis Aglogallos, Alexandros Bousdekis, Stefanos Kontos, Gregoris Mentzas

Introduction: Predictive maintenance has emerged as a critical strategy in modern manufacturing, in the frame of Industry 4.0, enabling proactive intervention before equipment failure. However, traditional machine learning approaches require extensive labeled data and lack adaptability to evolving operational conditions. On the other hand, Reinforcement Learning (RL) enables agents to learn optimal policies through interaction with the environment, eliminating the need for labeled datasets and naturally capturing the sequential, uncertain dynamics of equipment degradation.

Methods: In this paper, we propose an approach that incorporates four model-free RL algorithms, namely Proximal Policy Optimization (PPO), Advantage Actor-Critic (A2C), Deep Deterministic Policy Gradient (DDPG), and Soft Actor-Critic (SAC). We formulate the problem as a Markov Decision Process (MDP), which is solved with the aforementioned RL algorithms.

Results: The proposed approach is validated in the context of CNC machine tool wear prediction, using sensor data from the 2010 PHM Society Data Challenge. We examine algorithmic performance across four custom made environments, corrective and non-corrective environments both with and without delay correction mechanisms in order to compare learning dynamics, convergence behavior, and generalization aspects. Our results reveal that PPO and SAC achieve the most stable and efficient performance, with SAC excelling in structured environments and PPO demonstrating robust generalization. A2C shows consistent long-term learning, while DDPG underperforms due to insufficient exploration.

Discussion: The findings highlight the potential of RL for predictive maintenance applications and underscore the importance of aligning algorithm design with environment characteristics and reward structures.

导言:在工业4.0的框架下,预测性维护已经成为现代制造业的一项关键战略,可以在设备故障之前进行主动干预。然而,传统的机器学习方法需要大量的标记数据,并且缺乏对不断变化的操作条件的适应性。另一方面,强化学习(RL)使智能体能够通过与环境的交互来学习最佳策略,消除了对标记数据集的需求,并自然地捕获设备退化的顺序,不确定动态。方法:在本文中,我们提出了一种结合四种无模型RL算法的方法,即近端策略优化(PPO),优势行为者-批评者(A2C),深度确定性策略梯度(DDPG)和软行为者-批评者(SAC)。我们将该问题表述为马尔可夫决策过程(MDP),并使用上述强化学习算法解决该问题。结果:所提出的方法在CNC机床磨损预测的背景下得到了验证,使用了2010年PHM协会数据挑战赛的传感器数据。为了比较学习动态、收敛行为和泛化方面,我们检查了算法在四种定制环境中的性能,校正和非校正环境中有和没有延迟校正机制。我们的研究结果表明,PPO和SAC实现了最稳定和有效的性能,SAC在结构化环境中表现出色,PPO表现出鲁棒泛化。A2C表现出持续的长期学习,而DDPG表现不佳,主要是勘探不足。讨论:研究结果强调了强化学习在预测性维护应用中的潜力,并强调了将算法设计与环境特征和奖励结构相结合的重要性。
{"title":"Health state prediction with reinforcement learning for predictive maintenance.","authors":"Anastasis Aglogallos, Alexandros Bousdekis, Stefanos Kontos, Gregoris Mentzas","doi":"10.3389/frai.2025.1720140","DOIUrl":"10.3389/frai.2025.1720140","url":null,"abstract":"<p><strong>Introduction: </strong>Predictive maintenance has emerged as a critical strategy in modern manufacturing, in the frame of Industry 4.0, enabling proactive intervention before equipment failure. However, traditional machine learning approaches require extensive labeled data and lack adaptability to evolving operational conditions. On the other hand, Reinforcement Learning (RL) enables agents to learn optimal policies through interaction with the environment, eliminating the need for labeled datasets and naturally capturing the sequential, uncertain dynamics of equipment degradation.</p><p><strong>Methods: </strong>In this paper, we propose an approach that incorporates four model-free RL algorithms, namely Proximal Policy Optimization (PPO), Advantage Actor-Critic (A2C), Deep Deterministic Policy Gradient (DDPG), and Soft Actor-Critic (SAC). We formulate the problem as a Markov Decision Process (MDP), which is solved with the aforementioned RL algorithms.</p><p><strong>Results: </strong>The proposed approach is validated in the context of CNC machine tool wear prediction, using sensor data from the 2010 PHM Society Data Challenge. We examine algorithmic performance across four custom made environments, corrective and non-corrective environments both with and without delay correction mechanisms in order to compare learning dynamics, convergence behavior, and generalization aspects. Our results reveal that PPO and SAC achieve the most stable and efficient performance, with SAC excelling in structured environments and PPO demonstrating robust generalization. A2C shows consistent long-term learning, while DDPG underperforms due to insufficient exploration.</p><p><strong>Discussion: </strong>The findings highlight the potential of RL for predictive maintenance applications and underscore the importance of aligning algorithm design with environment characteristics and reward structures.</p>","PeriodicalId":33315,"journal":{"name":"Frontiers in Artificial Intelligence","volume":"8 ","pages":"1720140"},"PeriodicalIF":4.7,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12833388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146067352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
User perceptions of RBI-approved P2P digital lending apps: an NLP, machine learning, and deep learning approach. 用户对印度储备银行批准的P2P数字借贷应用程序的看法:NLP、机器学习和深度学习方法。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1708080
Kunchakara Raja Sekhar, Shaiku Shahida Saheb

Introduction: Digital lending, also known as alternative lending, refers to fintech platforms that offer quick and easy loans through digital channels, bypassing many of the limitations of traditional banking. Since the mid-2000s, digital lending has become a major fintech innovation, with rapid growth in India driven by financial inclusion measures. However, the sector continues to face challenges, including fraud, transparency issues, and consumer dissatisfaction. The primary objective of this study was to understand how consumers perceive and assess India's RBI-approved P2P digital lending apps by analyzing a large dataset of customer feedback to identify strengths, weaknesses, and overall satisfaction levels.

Methods: The study analyzed a final dataset of 15,408 user reviews collected from seven RBI-approved digital lending platforms: 5Paisa, Faircent, i2iFunding, LenDenClub, CashKumar, Lendbox, and IndiaMoneyMart derived from an initial 15,537 reviews. The cleaned data was then examined using natural language processing, topic modeling, and supervised machine learning and deep learning models to identify key themes and evaluate predictive performance.

Results: Topic modeling identified 11 recurring topics. Sentiment analysis revealed that 55% of evaluations were positive, 41% were negative, and 4% were neutral. Strengths included loan disbursement, withdrawals, and EMI payments, while weaknesses involved interface design, transparency around rejections, and login functionality. Comparative data revealed that IndiaMoneyMart and i2iFunding received the highest user satisfaction, while 5Paisa and Lendbox trailed due to recurring complaints about transparency, accessibility, and overall user experience. In terms of modeling, the deep learning model VGG16 and ensemble machine learning techniques (XGBoost, CatBoost, and LightGBM) consistently achieved the highest predictive accuracy (up to 0.88), outperforming simpler models such as decision trees and ResNets.

Discussion: The findings indicate that digital lending platforms support financial inclusion but require improvements in user interface and user experience, better transparency in loan decisions, and stronger customer support. Addressing these areas can help strengthen trust and promote long term adoption of digital lending services.

简介:数字借贷,又称另类借贷,是指金融科技平台通过数字渠道提供快速便捷的贷款,绕过了传统银行的诸多限制。自2000年代中期以来,数字贷款已成为一项主要的金融科技创新,在金融普惠措施的推动下,印度的数字贷款增长迅速。然而,该行业继续面临挑战,包括欺诈、透明度问题和消费者不满。本研究的主要目的是通过分析客户反馈的大型数据集来确定优势、劣势和总体满意度,了解消费者如何看待和评估印度央行批准的P2P数字借贷应用程序。方法:该研究分析了从7个印度央行批准的数字借贷平台收集的15408条用户评论的最终数据集:5Paisa, Faircent, i2iffunding, LenDenClub, CashKumar, Lendbox和indiammoneymart,这些平台收集了最初的15537条评论。然后使用自然语言处理、主题建模、监督机器学习和深度学习模型检查清理后的数据,以确定关键主题并评估预测性能。结果:主题建模确定了11个重复主题。情绪分析显示,55%的评价是正面的,41%是负面的,4%是中性的。优点包括贷款支付、取款和EMI支付,而缺点涉及界面设计、拒绝的透明度和登录功能。比较数据显示,indiammoneymart和i2iffunding获得了最高的用户满意度,而5Paisa和Lendbox则因为反复出现的透明度、可访问性和整体用户体验方面的投诉而落后。在建模方面,深度学习模型VGG16和集成机器学习技术(XGBoost、CatBoost和LightGBM)始终实现了最高的预测精度(高达0.88),优于决策树和ResNets等简单模型。讨论:研究结果表明,数字借贷平台支持普惠金融,但需要改进用户界面和用户体验,提高贷款决策的透明度,并加强客户支持。解决这些问题有助于加强信任,促进数字借贷服务的长期采用。
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引用次数: 0
From the logic of coordination to goal-directed reasoning: the agentic turn in artificial intelligence. 从协调逻辑到目标导向推理:人工智能中的代理转向。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1728738
Tsehaye Haidemariam

The rise of agentic artificial intelligence (Agentic AI) marks a transition from systems that optimize externally specified objectives to systems capable of representing, evaluating, and revising their own goals. Whereas earlier AI architectures executed fixed task specifications, agentic systems maintain recursive loops of perception, evaluation, goal-updating, and action, allowing them to sustain and adapt purposive activity across temporal and organizational scales. This paper argues that Agentic AI is not an incremental extension of large language models (LLMs) or autonomous agents in the sense we know it from classical AI and multi-agent systems, but a reconstitution of agency itself within computational substrates. Building on the logic of coordination, delegation, and self-regulation developed in early agent-based process management systems, we propose a general theory of synthetic purposiveness, where agency emerges as a distributed and self-maintaining property of artificial systems operating in open-ended environments. We develop the concept of synthetic teleology-the engineered capacity of artificial systems to generate and regulate goals through ongoing self-evaluation-and we formalize its dynamics through a recursive goal-maintenance equation. We further outline design patterns, computational semantics, and measurable indicators of purposiveness (e.g., teleological coherence, adaptive recovery, and reflective efficiency), providing a foundation for the systematic design and empirical investigation of agentic behaviour. By reclaiming agency as a first-class construct in artificial intelligence, we argue for a paradigm shift from algorithmic optimization toward goal-directed reasoning and purposive orchestration-one with far-reaching epistemic, societal, and institutional consequences.

人工智能(agent AI)的兴起标志着从优化外部指定目标的系统向能够表示、评估和修改自己目标的系统的转变。早期的人工智能架构执行固定的任务规范,而代理系统维持感知、评估、目标更新和行动的递归循环,允许它们在时间和组织尺度上维持和适应有目的的活动。本文认为,人工智能不是大型语言模型(llm)的增量扩展,也不是我们从经典人工智能和多智能体系统中了解到的自主智能体,而是在计算基础上对代理本身的重构。在早期基于代理的过程管理系统中发展的协调、授权和自我调节逻辑的基础上,我们提出了一种综合合意性的一般理论,其中代理作为在开放式环境中运行的人工系统的分布式和自我维护属性而出现。我们发展了合成目的论的概念——人工系统通过持续的自我评估产生和调节目标的工程能力——我们通过递归的目标维持方程形式化了它的动力学。我们进一步概述了设计模式、计算语义和可测量的合向性指标(例如,目的性一致性、适应性恢复和反射效率),为代理行为的系统设计和实证研究提供了基础。通过将代理重新定义为人工智能中的一流结构,我们主张从算法优化到目标导向推理和有目的的编排的范式转变-具有深远的认知,社会和制度后果。
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引用次数: 0
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