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Deep learning and machine learning integration of radiomics and transcriptomics predicts response-adapted radiotherapy outcome and radiosensitivity in resectable locally advanced laryngeal carcinoma. 放射组学和转录组学的深度学习和机器学习集成预测可切除的局部晚期喉癌的反应适应放射治疗结果和放射敏感性。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1738174
Shafat Ujjahan, Abu Shadat M Noman, Sarah S Al-Johani, Zakia Shinwari, Ayodele A Alaiya, Syed S Islam
<p><strong>Background: </strong>Radiotherapy (RT) remains a cornerstone treatment for head and neck cancer squamous cell carcinoma. However, therapeutic responses vary considerably among patients due to radiation resistance, which limits long-term survival and contributes to recurrence and disease progression. Developing robust deep learning (DL) and machine learning (ML)-based predictive models is essential to improve response prediction, evaluate treatment outcomes, and identify biomarkers linked to radiosensitization.</p><p><strong>Methods: </strong>This single-center retrospective study applied DL and ML models to analyze CT scans and RNA-seq gene expression data for prognostic and biomarker discovery purposes. For image analyses, two independent datasets were used. Dataset A includes 1,100 CT scans (pre- and post-treatment) from 476 patients with stage III and IV laryngeal carcinoma treated with response-adapted RT. A convolutional neural network (CNNs) integrated with a recurrent network (RNNs) was used for single-point tumor localization and response prediction. Dataset B, comprising 500 scans from 169 patients treated with radical RT, served as the additional validation cohort. Pre- and post-treatment scans were used to train a DL model, which showed better prediction performance for survival and disease-specific outcomes, including progression and locoregional recurrence. For gene expression-based biomarker analysis, TCGA data (<i>n</i> = 231) were examined using glmBoost, support vector machine classifier (SVM), and random forest (RF) algorithms to construct and predict genes associated with radiosensitivity, and the GSE20020 dataset was used to validate the model performance. Proteins and mRNA were used to confirm the signature biomarkers using qRT-PCR and LC-MS mass spectrometry.</p><p><strong>Findings: </strong>For CT scan image analysis, the DL-model achieved AUCs of 0.792 (<i>p</i> = 0.031) at 2-month and 0.832 (<i>p</i> < 0.01) at 6-month follow-up. Risk scores significantly correlated with overall survival (HR 1.59, 95% CI 1.34-3.22, <i>p</i> = 0.063), progression-free survival (1.39, 95% CI 1.16-2.29, <i>p</i> = 0.103). The pathological response in dataset B was likewise significantly predicted by the model. Among 39 differentially expressed genes, ML-model analysis identified 13 candidate genes associated with radiosensitivity on repeated cross-validation with an AUROC of 0.91 in the training set. In the validation dataset, when the models were optimized, the models consistently predicted seven core genes, achieving AUCs ranging from 0.96 to 0.94 to predict the radiosensitivity.</p><p><strong>Interpretation: </strong>These findings highlight the effectiveness of DL and ML approaches in integrating imaging and transcriptomic data to predict response-adapted RT response and patient outcomes. These automated, and interpretable AI-driven biomarkers hold significant potential for clinical translation. Future research should aim to e
背景:放疗(RT)仍然是头颈癌鳞状细胞癌的基础治疗方法。然而,由于放射耐药,患者之间的治疗反应差异很大,这限制了长期生存并导致复发和疾病进展。开发强大的基于深度学习(DL)和机器学习(ML)的预测模型对于改善反应预测、评估治疗结果和识别与放射致敏相关的生物标志物至关重要。方法:这项单中心回顾性研究应用DL和ML模型分析CT扫描和RNA-seq基因表达数据,以发现预后和生物标志物。对于图像分析,使用了两个独立的数据集。数据集A包括476例接受反应性rt治疗的III期和IV期喉癌患者的1100次CT扫描(治疗前和治疗后)。卷积神经网络(cnn)与复发性网络(rnn)相结合用于单点肿瘤定位和反应预测。数据集B包括来自169名接受根治性放疗的患者的500次扫描,作为额外的验证队列。治疗前和治疗后扫描用于训练DL模型,该模型对生存和疾病特异性结果(包括进展和局部复发)显示出更好的预测性能。对于基于基因表达的生物标志物分析,使用glmBoost、支持向量机分类器(SVM)和随机森林(RF)算法对TCGA数据(n = 231)进行检查,构建和预测与放射敏感性相关的基因,并使用GSE20020数据集验证模型的性能。采用qRT-PCR和LC-MS质谱法对蛋白质和mRNA进行鉴定。结果:对于CT扫描图像分析,dl模型在2个月时的auc为0.792 (p = 0.031),0.832 (p p = 0.063),无进展生存期(1.39,95% CI 1.16-2.29, p = 0.103)。数据集B中的病理反应同样被该模型显著预测。在39个差异表达基因中,ml模型分析通过反复交叉验证确定了13个与放射敏感性相关的候选基因,训练集中的AUROC为0.91。在验证数据集中,优化模型后,模型对7个核心基因的预测一致,auc范围为0.96 ~ 0.94。解释:这些发现强调了DL和ML方法在整合成像和转录组学数据以预测反应适应的RT反应和患者结果方面的有效性。这些自动化的、可解释的人工智能驱动的生物标志物在临床翻译方面具有巨大的潜力。未来的研究应旨在扩大数据集,并在多中心队列中验证模型,以获得更广泛的适用性。
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引用次数: 0
The collaborations among healthcare systems, research institutions, and industry on artificial intelligence research and development. 医疗保健系统、研究机构和产业界在人工智能研发方面的合作。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1694145
Jiancheng Ye, Michelle Ma, Malak Abuhashish

Objectives: The integration of Artificial Intelligence (AI) in healthcare promises to revolutionize patient care, diagnostics, and treatment protocols. Collaborative efforts among healthcare systems, research institutions, and industry are pivotal to leveraging AI's full potential. Understanding these dynamics is essential for addressing current challenges and shaping future AI development in healthcare. This study aims to characterize collaborative networks and stakeholders in AI healthcare initiatives, identify challenges and opportunities within these collaborations, and elucidate priorities for future AI research and development.

Methods: This study analyzed publicly available survey data previously collected by the Chinese Society of Radiology and the Chinese Medical Imaging AI Innovation Alliance. We performed secondary analysis of the national cross-sectional survey that was conducted in China with a total of 5,262 participants (5,142 clinicians and 120 research institution professionals), involving participants from three key groups: clinicians, institution professionals, and industry representatives. The survey explored diverse aspects including current AI usage in healthcare, collaboration dynamics, challenges encountered, and research and development priorities.

Results: Findings reveal high interest in AI among clinicians, with a significant gap between interest and actual engagement in development activities. Key findings include limited establishment of AI research departments and scarce interdisciplinary collaborations. Despite the willingness to share data, progress is hindered by concerns about data privacy and security, and lack of clear industry standards and legal guidelines. Future development interests focus on lesion screening, disease diagnosis, and enhancing clinical workflows.

Conclusion: This study highlights an enthusiastic yet cautious approach toward AI in healthcare, characterized by significant barriers that impede effective collaboration and implementation. Recommendations emphasize the need for AI-specific education and training, secure data-sharing frameworks, establishment of clear industry standards, and formation of dedicated AI research departments.

目标:人工智能(AI)在医疗保健领域的整合有望彻底改变患者护理、诊断和治疗方案。医疗保健系统、研究机构和行业之间的协作努力对于充分利用人工智能的潜力至关重要。了解这些动态对于应对当前挑战和塑造医疗保健领域未来的人工智能发展至关重要。本研究旨在描述人工智能医疗保健计划中的协作网络和利益相关者,确定这些合作中的挑战和机遇,并阐明未来人工智能研究和开发的优先事项。方法:本研究分析了中国放射学会和中国医学成像人工智能创新联盟之前收集的公开调查数据。我们对在中国进行的全国横断面调查进行了二次分析,共有5262名参与者(5142名临床医生和120名研究机构专业人员),参与者来自三个关键群体:临床医生、机构专业人员和行业代表。该调查探讨了多个方面,包括当前人工智能在医疗保健领域的使用、协作动态、遇到的挑战以及研发优先事项。结果:研究结果显示,临床医生对人工智能的兴趣很高,但在兴趣和实际参与开发活动之间存在显著差距。主要发现包括人工智能研究部门的建立有限,跨学科合作稀缺。尽管有共享数据的意愿,但对数据隐私和安全的担忧,以及缺乏明确的行业标准和法律指导方针,阻碍了进展。未来的发展重点是病变筛查、疾病诊断和增强临床工作流程。结论:本研究强调了对医疗保健领域人工智能的热情而谨慎的态度,其特点是阻碍有效合作和实施的重大障碍。建议强调需要针对人工智能的教育和培训,安全的数据共享框架,建立明确的行业标准,以及组建专门的人工智能研究部门。
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引用次数: 0
Health state prediction with reinforcement learning for predictive maintenance. 使用用于预测性维护的强化学习进行健康状态预测。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1720140
Anastasis Aglogallos, Alexandros Bousdekis, Stefanos Kontos, Gregoris Mentzas

Introduction: Predictive maintenance has emerged as a critical strategy in modern manufacturing, in the frame of Industry 4.0, enabling proactive intervention before equipment failure. However, traditional machine learning approaches require extensive labeled data and lack adaptability to evolving operational conditions. On the other hand, Reinforcement Learning (RL) enables agents to learn optimal policies through interaction with the environment, eliminating the need for labeled datasets and naturally capturing the sequential, uncertain dynamics of equipment degradation.

Methods: In this paper, we propose an approach that incorporates four model-free RL algorithms, namely Proximal Policy Optimization (PPO), Advantage Actor-Critic (A2C), Deep Deterministic Policy Gradient (DDPG), and Soft Actor-Critic (SAC). We formulate the problem as a Markov Decision Process (MDP), which is solved with the aforementioned RL algorithms.

Results: The proposed approach is validated in the context of CNC machine tool wear prediction, using sensor data from the 2010 PHM Society Data Challenge. We examine algorithmic performance across four custom made environments, corrective and non-corrective environments both with and without delay correction mechanisms in order to compare learning dynamics, convergence behavior, and generalization aspects. Our results reveal that PPO and SAC achieve the most stable and efficient performance, with SAC excelling in structured environments and PPO demonstrating robust generalization. A2C shows consistent long-term learning, while DDPG underperforms due to insufficient exploration.

Discussion: The findings highlight the potential of RL for predictive maintenance applications and underscore the importance of aligning algorithm design with environment characteristics and reward structures.

导言:在工业4.0的框架下,预测性维护已经成为现代制造业的一项关键战略,可以在设备故障之前进行主动干预。然而,传统的机器学习方法需要大量的标记数据,并且缺乏对不断变化的操作条件的适应性。另一方面,强化学习(RL)使智能体能够通过与环境的交互来学习最佳策略,消除了对标记数据集的需求,并自然地捕获设备退化的顺序,不确定动态。方法:在本文中,我们提出了一种结合四种无模型RL算法的方法,即近端策略优化(PPO),优势行为者-批评者(A2C),深度确定性策略梯度(DDPG)和软行为者-批评者(SAC)。我们将该问题表述为马尔可夫决策过程(MDP),并使用上述强化学习算法解决该问题。结果:所提出的方法在CNC机床磨损预测的背景下得到了验证,使用了2010年PHM协会数据挑战赛的传感器数据。为了比较学习动态、收敛行为和泛化方面,我们检查了算法在四种定制环境中的性能,校正和非校正环境中有和没有延迟校正机制。我们的研究结果表明,PPO和SAC实现了最稳定和有效的性能,SAC在结构化环境中表现出色,PPO表现出鲁棒泛化。A2C表现出持续的长期学习,而DDPG表现不佳,主要是勘探不足。讨论:研究结果强调了强化学习在预测性维护应用中的潜力,并强调了将算法设计与环境特征和奖励结构相结合的重要性。
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引用次数: 0
User perceptions of RBI-approved P2P digital lending apps: an NLP, machine learning, and deep learning approach. 用户对印度储备银行批准的P2P数字借贷应用程序的看法:NLP、机器学习和深度学习方法。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1708080
Kunchakara Raja Sekhar, Shaiku Shahida Saheb

Introduction: Digital lending, also known as alternative lending, refers to fintech platforms that offer quick and easy loans through digital channels, bypassing many of the limitations of traditional banking. Since the mid-2000s, digital lending has become a major fintech innovation, with rapid growth in India driven by financial inclusion measures. However, the sector continues to face challenges, including fraud, transparency issues, and consumer dissatisfaction. The primary objective of this study was to understand how consumers perceive and assess India's RBI-approved P2P digital lending apps by analyzing a large dataset of customer feedback to identify strengths, weaknesses, and overall satisfaction levels.

Methods: The study analyzed a final dataset of 15,408 user reviews collected from seven RBI-approved digital lending platforms: 5Paisa, Faircent, i2iFunding, LenDenClub, CashKumar, Lendbox, and IndiaMoneyMart derived from an initial 15,537 reviews. The cleaned data was then examined using natural language processing, topic modeling, and supervised machine learning and deep learning models to identify key themes and evaluate predictive performance.

Results: Topic modeling identified 11 recurring topics. Sentiment analysis revealed that 55% of evaluations were positive, 41% were negative, and 4% were neutral. Strengths included loan disbursement, withdrawals, and EMI payments, while weaknesses involved interface design, transparency around rejections, and login functionality. Comparative data revealed that IndiaMoneyMart and i2iFunding received the highest user satisfaction, while 5Paisa and Lendbox trailed due to recurring complaints about transparency, accessibility, and overall user experience. In terms of modeling, the deep learning model VGG16 and ensemble machine learning techniques (XGBoost, CatBoost, and LightGBM) consistently achieved the highest predictive accuracy (up to 0.88), outperforming simpler models such as decision trees and ResNets.

Discussion: The findings indicate that digital lending platforms support financial inclusion but require improvements in user interface and user experience, better transparency in loan decisions, and stronger customer support. Addressing these areas can help strengthen trust and promote long term adoption of digital lending services.

简介:数字借贷,又称另类借贷,是指金融科技平台通过数字渠道提供快速便捷的贷款,绕过了传统银行的诸多限制。自2000年代中期以来,数字贷款已成为一项主要的金融科技创新,在金融普惠措施的推动下,印度的数字贷款增长迅速。然而,该行业继续面临挑战,包括欺诈、透明度问题和消费者不满。本研究的主要目的是通过分析客户反馈的大型数据集来确定优势、劣势和总体满意度,了解消费者如何看待和评估印度央行批准的P2P数字借贷应用程序。方法:该研究分析了从7个印度央行批准的数字借贷平台收集的15408条用户评论的最终数据集:5Paisa, Faircent, i2iffunding, LenDenClub, CashKumar, Lendbox和indiammoneymart,这些平台收集了最初的15537条评论。然后使用自然语言处理、主题建模、监督机器学习和深度学习模型检查清理后的数据,以确定关键主题并评估预测性能。结果:主题建模确定了11个重复主题。情绪分析显示,55%的评价是正面的,41%是负面的,4%是中性的。优点包括贷款支付、取款和EMI支付,而缺点涉及界面设计、拒绝的透明度和登录功能。比较数据显示,indiammoneymart和i2iffunding获得了最高的用户满意度,而5Paisa和Lendbox则因为反复出现的透明度、可访问性和整体用户体验方面的投诉而落后。在建模方面,深度学习模型VGG16和集成机器学习技术(XGBoost、CatBoost和LightGBM)始终实现了最高的预测精度(高达0.88),优于决策树和ResNets等简单模型。讨论:研究结果表明,数字借贷平台支持普惠金融,但需要改进用户界面和用户体验,提高贷款决策的透明度,并加强客户支持。解决这些问题有助于加强信任,促进数字借贷服务的长期采用。
{"title":"User perceptions of RBI-approved P2P digital lending apps: an NLP, machine learning, and deep learning approach.","authors":"Kunchakara Raja Sekhar, Shaiku Shahida Saheb","doi":"10.3389/frai.2025.1708080","DOIUrl":"10.3389/frai.2025.1708080","url":null,"abstract":"<p><strong>Introduction: </strong>Digital lending, also known as alternative lending, refers to fintech platforms that offer quick and easy loans through digital channels, bypassing many of the limitations of traditional banking. Since the mid-2000s, digital lending has become a major fintech innovation, with rapid growth in India driven by financial inclusion measures. However, the sector continues to face challenges, including fraud, transparency issues, and consumer dissatisfaction. The primary objective of this study was to understand how consumers perceive and assess India's RBI-approved P2P digital lending apps by analyzing a large dataset of customer feedback to identify strengths, weaknesses, and overall satisfaction levels.</p><p><strong>Methods: </strong>The study analyzed a final dataset of 15,408 user reviews collected from seven RBI-approved digital lending platforms: 5Paisa, Faircent, i2iFunding, LenDenClub, CashKumar, Lendbox, and IndiaMoneyMart derived from an initial 15,537 reviews. The cleaned data was then examined using natural language processing, topic modeling, and supervised machine learning and deep learning models to identify key themes and evaluate predictive performance.</p><p><strong>Results: </strong>Topic modeling identified 11 recurring topics. Sentiment analysis revealed that 55% of evaluations were positive, 41% were negative, and 4% were neutral. Strengths included loan disbursement, withdrawals, and EMI payments, while weaknesses involved interface design, transparency around rejections, and login functionality. Comparative data revealed that IndiaMoneyMart and i2iFunding received the highest user satisfaction, while 5Paisa and Lendbox trailed due to recurring complaints about transparency, accessibility, and overall user experience. In terms of modeling, the deep learning model VGG16 and ensemble machine learning techniques (XGBoost, CatBoost, and LightGBM) consistently achieved the highest predictive accuracy (up to 0.88), outperforming simpler models such as decision trees and ResNets.</p><p><strong>Discussion: </strong>The findings indicate that digital lending platforms support financial inclusion but require improvements in user interface and user experience, better transparency in loan decisions, and stronger customer support. Addressing these areas can help strengthen trust and promote long term adoption of digital lending services.</p>","PeriodicalId":33315,"journal":{"name":"Frontiers in Artificial Intelligence","volume":"8 ","pages":"1708080"},"PeriodicalIF":4.7,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12832989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146067376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From the logic of coordination to goal-directed reasoning: the agentic turn in artificial intelligence. 从协调逻辑到目标导向推理:人工智能中的代理转向。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1728738
Tsehaye Haidemariam

The rise of agentic artificial intelligence (Agentic AI) marks a transition from systems that optimize externally specified objectives to systems capable of representing, evaluating, and revising their own goals. Whereas earlier AI architectures executed fixed task specifications, agentic systems maintain recursive loops of perception, evaluation, goal-updating, and action, allowing them to sustain and adapt purposive activity across temporal and organizational scales. This paper argues that Agentic AI is not an incremental extension of large language models (LLMs) or autonomous agents in the sense we know it from classical AI and multi-agent systems, but a reconstitution of agency itself within computational substrates. Building on the logic of coordination, delegation, and self-regulation developed in early agent-based process management systems, we propose a general theory of synthetic purposiveness, where agency emerges as a distributed and self-maintaining property of artificial systems operating in open-ended environments. We develop the concept of synthetic teleology-the engineered capacity of artificial systems to generate and regulate goals through ongoing self-evaluation-and we formalize its dynamics through a recursive goal-maintenance equation. We further outline design patterns, computational semantics, and measurable indicators of purposiveness (e.g., teleological coherence, adaptive recovery, and reflective efficiency), providing a foundation for the systematic design and empirical investigation of agentic behaviour. By reclaiming agency as a first-class construct in artificial intelligence, we argue for a paradigm shift from algorithmic optimization toward goal-directed reasoning and purposive orchestration-one with far-reaching epistemic, societal, and institutional consequences.

人工智能(agent AI)的兴起标志着从优化外部指定目标的系统向能够表示、评估和修改自己目标的系统的转变。早期的人工智能架构执行固定的任务规范,而代理系统维持感知、评估、目标更新和行动的递归循环,允许它们在时间和组织尺度上维持和适应有目的的活动。本文认为,人工智能不是大型语言模型(llm)的增量扩展,也不是我们从经典人工智能和多智能体系统中了解到的自主智能体,而是在计算基础上对代理本身的重构。在早期基于代理的过程管理系统中发展的协调、授权和自我调节逻辑的基础上,我们提出了一种综合合意性的一般理论,其中代理作为在开放式环境中运行的人工系统的分布式和自我维护属性而出现。我们发展了合成目的论的概念——人工系统通过持续的自我评估产生和调节目标的工程能力——我们通过递归的目标维持方程形式化了它的动力学。我们进一步概述了设计模式、计算语义和可测量的合向性指标(例如,目的性一致性、适应性恢复和反射效率),为代理行为的系统设计和实证研究提供了基础。通过将代理重新定义为人工智能中的一流结构,我们主张从算法优化到目标导向推理和有目的的编排的范式转变-具有深远的认知,社会和制度后果。
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引用次数: 0
Optimized ensemble machine learning model for cyberattack classification in industrial IoT. 工业物联网网络攻击分类的优化集成机器学习模型。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1685376
Batool Alabdullah, Suresh Sankaranarayanan

Introduction: The increasing cyber threats targeting industrial control systems (ICS) and the Internet of Things (IoT) pose significant risks, especially in critical infrastructures like the oil and gas sector. Existing machine learning (ML) approaches for cyberattack detection often rely on binary classification and lack computational efficiency.

Methods: This study proposes two optimized stacked ensemble models to enhance attack detection accuracy while reducing computational overhead. The main contribution lies in the strategic selection and integration of diverse base models, such as Logistic Regression, Extra Tree Classifier, XGBoost, and LGBM, with RFC as the final estimator. These models are chosen to address unique characteristics of security datasets, such as class imbalance, noise, and complex attack patterns. This combination aims to leverage different decision boundaries and learning mechanisms.

Results: Evaluations show that the Stacked Ensemble_2 model achieves 97% accuracy with a training and testing computation time of 54 minutes. Stacked Ensemble_2, which excelled over the traditional Stacked Ensemble_1, was also evaluated on the CICIDS 2017 dataset, achieving an impressive 100% accuracy with an AUROC of 99%.

Discussion: The results indicate that the proposed Stacked Ensemble_2 model provides a scalable, real-time detection mechanism for securing ICS and IoT environments. By proving its effectiveness on unseen data, this model demonstrates a significant advancement over traditional methods, offering enhanced accuracy and efficiency in detecting sophisticated cyber threats in critical infrastructure sectors.

导语:越来越多的针对工业控制系统(ICS)和物联网(IoT)的网络威胁构成了重大风险,特别是在石油和天然气行业等关键基础设施中。现有的机器学习(ML)网络攻击检测方法往往依赖于二进制分类,缺乏计算效率。方法:提出两种优化的堆叠集成模型,在降低计算开销的同时提高攻击检测精度。主要贡献在于策略性地选择和整合各种基本模型,如Logistic回归、Extra Tree Classifier、XGBoost和LGBM,并以RFC作为最终的估计器。选择这些模型是为了解决安全数据集的独特特征,例如类不平衡、噪声和复杂的攻击模式。这种组合旨在利用不同的决策边界和学习机制。结果:评价表明,该模型的训练和测试计算时间为54分钟,准确率达到97%。在CICIDS 2017数据集上,对优于传统堆叠Ensemble_1的堆叠Ensemble_2进行了评估,达到了令人印象深刻的100%准确率和99%的AUROC。讨论:结果表明,所提出的堆叠集成模型为保护ICS和物联网环境提供了一种可扩展的实时检测机制。通过证明其在看不见的数据上的有效性,该模型显示了比传统方法的重大进步,在检测关键基础设施部门的复杂网络威胁方面提供了更高的准确性和效率。
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引用次数: 0
RiCoRecA: rich cooking recipe annotation schema. RiCoRecA:丰富的烹饪食谱注释模式。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1550604
Filippos Ventirozos, Mauricio Jacobo-Romero, Haifa Alrdahi, Sarah Clinch, Riza Batista-Navarro

Despite recent advancements, modern kitchens, at best, have one or more isolated (non-communicating) "smart" devices. The vision of having a fully-fledged ambient kitchen where devices know what to do and when has yet to be realized. To address this, we present RiCoRecA, a novel schema for parsing cooking recipes into a workflow representation suitable for automation, a step toward that direction. Methodologically, the schema requires a number of information extraction tasks, i.e., annotating named entities, identifying relations between them, coreference resolution, and entity tracking. RiCoRecA differs from previously reported approaches in that it learns these different information extraction tasks using one joint model. We also provide a dataset containing annotations that follow this schema. Furthermore, we compared two transformer-based models for parsing recipes into workflows, namely, PEGASUS-X and LongT5. Our results demonstrate that PEGASUS-X surpassed LongT5 on all of the annotation tasks. Specifically, PEGASUS-X surpassed LongT5 by 39% in terms of F-Score when averaging the performance on all the tasks; it demonstrated almost human-like performance.

尽管最近取得了进步,但现代厨房最多只有一个或多个孤立的(非通信的)“智能”设备。拥有一个完全成熟的环境厨房,设备知道什么时候做什么,这一愿景尚未实现。为了解决这个问题,我们提出了RiCoRecA,这是一种新颖的模式,用于将烹饪食谱解析为适合自动化的工作流表示形式,朝着这个方向迈出了一步。在方法上,该模式需要许多信息提取任务,即注释命名实体、识别它们之间的关系、共同引用解析和实体跟踪。RiCoRecA与之前报道的方法不同,它使用一个联合模型来学习这些不同的信息提取任务。我们还提供了一个包含遵循此模式的注释的数据集。此外,我们比较了用于将食谱解析为工作流的两个基于转换器的模型,即PEGASUS-X和LongT5。我们的结果表明PEGASUS-X在所有注释任务上都超过了LongT5。具体来说,PEGASUS-X在所有任务的平均性能方面的F-Score超过了LongT5 39%;它展示了几乎与人类相似的表现。
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引用次数: 0
Enhanced multi-class object detector for bone fracture diagnosis with prescription recommendation. 基于处方推荐的增强多类目标检测器用于骨折诊断。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1692894
Daudi Mashauri Migayo, Shubi Kaijage, Stephen Swetala, Devotha G Nyambo

Bone fractures are among the most prominent injuries in the modern world that affect all ages and races. Traditional treatment involves radiographic imaging that relies heavily on radiologists manually analyzing images. There have been efforts to develop computer-aided diagnosis tools that employ artificial intelligence and deep learning approaches. Existing literature focuses on developing tools that only detect and classify bone fractures, rather than addressing the broader issue of bone fracture management. However, evidence of scholarly works that include treatment recommendations is still lacking. Furthermore, deep learning-based object detectors that achieve state-of-the-art results are computationally expensive and considered as black-box solutions. Developing countries, such as Sub-Saharan Africa, face a shortage of radiologists and orthopedists. For this reason, this paper proposes a methodological approach that uses a more efficient object detection model to diagnose long bone fractures and provide prescription recommendations. An enhanced anchoring process, known as adaptive anchoring, is proposed to improve the performance of the Regional Proposal Network and the object detection model. A Faster R-CNN model with ResNet-50/101 and ResNext-50/101 backbones was used to develop an object detection model that uses X-ray images as input. To understand and interpret the model's decision, a Gradient-based Class Activation Mapping method was used to assess the model's learnability. The results indicate that the proposed adaptive anchoring approach can improve computational efficiency, reducing training time by up to 29% compared to the traditional approach. Model accuracy during training and validation ranged between 94% and 98%. Overall, adaptive anchoring performed better when applied with the ResNet-101 backbone, yielding an Average Precision of 92.73%, an F1 score of 96.01%, a precision of 96.80%, and a recall of 95.23%. The study provides valuable insights into the use of computationally efficient deep learning models for medical recommendation systems. Future studies should develop models to diagnose fractures using input images from various modalities and to provide prescription recommendations.

骨折是现代世界中影响所有年龄和种族的最突出的伤害之一。传统的治疗包括放射成像,严重依赖放射科医生手动分析图像。人们一直在努力开发利用人工智能和深度学习方法的计算机辅助诊断工具。现有文献侧重于开发仅检测和分类骨折的工具,而不是解决骨折管理的更广泛问题。然而,包括治疗建议的学术著作的证据仍然缺乏。此外,基于深度学习的目标检测器实现了最先进的结果,计算成本很高,被认为是黑盒解决方案。发展中国家,如撒哈拉以南非洲,面临着放射科医生和骨科医生的短缺。因此,本文提出了一种方法学方法,使用更有效的目标检测模型来诊断长骨骨折并提供处方建议。提出了一种增强的锚定过程,称为自适应锚定,以提高区域建议网络和目标检测模型的性能。采用基于ResNet-50/101和ResNext-50/101主干的Faster R-CNN模型,开发以x射线图像为输入的目标检测模型。为了理解和解释模型的决策,使用基于梯度的类激活映射方法来评估模型的可学习性。结果表明,与传统方法相比,所提出的自适应锚定方法可以提高计算效率,减少高达29%的训练时间。模型在训练和验证期间的准确率在94%到98%之间。总体而言,自适应锚定在ResNet-101骨干网中表现更好,平均精度为92.73%,F1分数为96.01%,精度为96.80%,召回率为95.23%。该研究为医疗推荐系统使用计算效率高的深度学习模型提供了有价值的见解。未来的研究应该建立模型,利用不同模式的输入图像来诊断骨折,并提供处方建议。
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引用次数: 0
Improved attention-based PCNN with GhostNet for epilepsy seizure detection using EEG and fMRI modalities: extractive pattern and histogram feature set. 基于GhostNet的改进的基于注意力的PCNN用于脑电图和功能磁共振成像的癫痫发作检测:提取模式和直方图特征集。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1679218
Sunkara Mounika, Reeja S R

Introduction: Detecting epileptic seizures remains a major challenge in clinical neurology due to the complex, heterogeneous, and non-stationary characteristics of electroencephalogram (EEG) signals. Although recent machine learning (ML) and deep learning (DL) approaches have improved detection performance, most methods still struggle with limited interpretability, inadequate spatial-temporal modeling, and suboptimal generalization. To address these limitations, this study proposes an enhanced hybrid parallel convolutional-GhostNet framework (HPG-ESD) for robust seizure detection using multimodal EEG and functional Magnetic Resonance Imaging (fMRI) data.

Methods: The experimental data consist of pediatric scalp EEG recordings from 24 subjects in the CHB-MIT dataset (22-channel 10-20 system, 256 Hz sampling, continuous multi-hour recordings) and resting-state 3T fMRI scans from 52 participants in the UNAM TLE dataset (26 epilepsy patients and 26 healthy controls). EEG data underwent Gauss-based median filtering, while fMRI images were denoised using an adaptive weight-based Wiener filter. Spatial, temporal, and spectral EEG features were extracted alongside an enhanced common spatial pattern (E-CSP) representation, whereas fMRI features were obtained using deep 3D CNN embeddings combined with a smoothened pyramid histogram of oriented gradients (S-PHOG) descriptor. These multimodal features were fused within a soft voting hybrid parallel convolutional-GhostNet (S-HPCGN) model, integrating an improved attention based parallel convolutional network (IAPCNet) and GhostNet to capture complementary spatial-temporal patterns.

Results: The proposed HPG-ESD framework achieved an accuracy of 0.941, precision of 0.939, and sensitivity of 0.944, outperforming conventional unimodal and state-of-the-art methods.

Discussion: These results demonstrate the potential of multi-modal learning and lightweight attention-enhanced architectures for reliable and clinically relevant seizure detection.

由于脑电图(EEG)信号的复杂性、异质性和非平稳性,检测癫痫发作仍然是临床神经病学的主要挑战。尽管最近的机器学习(ML)和深度学习(DL)方法提高了检测性能,但大多数方法仍然存在有限的可解释性、不充分的时空建模和次优泛化的问题。为了解决这些限制,本研究提出了一种增强的混合并行卷积- ghostnet框架(HPG-ESD),用于使用多模态脑电图和功能磁共振成像(fMRI)数据进行稳健的癫痫检测。方法:实验数据包括来自CHB-MIT数据集(22通道10-20系统,256 Hz采样,连续多小时记录)的24名儿童头皮EEG记录和来自UNAM TLE数据集的52名参与者(26名癫痫患者和26名健康对照)的静息状态3T fMRI扫描。EEG数据采用高斯中值滤波,fMRI图像采用自适应加权维纳滤波去噪。通过增强的共同空间模式(E-CSP)表示提取EEG的空间、时间和频谱特征,而使用深度3D CNN嵌入结合平滑的定向梯度金字塔直方图(S-PHOG)描述符获得fMRI特征。这些多模态特征融合在软投票混合并行卷积-GhostNet (S-HPCGN)模型中,整合改进的基于注意力的并行卷积网络(IAPCNet)和GhostNet来捕捉互补的时空模式。结果:所提出的HPG-ESD框架的准确度为0.941,精密度为0.939,灵敏度为0.944,优于传统的单峰方法和最先进的方法。讨论:这些结果证明了多模式学习和轻量级注意力增强架构在可靠和临床相关的癫痫检测方面的潜力。
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引用次数: 0
Perception and awareness of healthcare professionals toward the applications of artificial intelligence in Egyptian healthcare settings. 感知和医疗保健专业人员对人工智能在埃及医疗保健设置的应用意识。
IF 4.7 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frai.2025.1700493
Shimaa Azzam, El-Morsy Ahmed El-Morsy, Amira S A Said, Nermin Eissa, Doaa Mahmoud Khalil

Background: Healthcare professionals' awareness and handling of artificial intelligence applications in healthcare enhance patient outcomes and improve processes. This study aimed to evaluate the perception, attitude, knowledge, and practice of healthcare professionals regarding the application of artificial intelligence in Egyptian healthcare settings.

Method: A cross-sectional study in which 367 healthcare professionals responded to an electronic questionnaire.

Results: Out of 367 participants (234 female), radiology and lab test specialty (36.2%) was the predominant. The mean age was 27.03 years; 51.8% of respondents showed positive perception, 68.7% experienced sub-optimal knowledge, 52.9% expressed negative attitudes, and 53.4% demonstrated a low practice level of AI tools. Younger age was significantly associated with positive perception (adjusted odds ratio (AOR) = 0.905, p = 0.020) and higher AI practice (AOR = 0.907, p = 0.026). University hospital professionals had 61.4% lower odds of optimal knowledge than private hospital professionals (AOR = 0.386, p = 0.046). Men had higher odds of both positive attitudes (AOR = 1.844, p = 0.010) and high practice level (AOR = 2.92, p < 0.001). Pre-bachelor's holders had lower odds of positive attitudes (AOR = 0.361, p = 0.036), as well as physicians compared to nurses and others (AOR = 0.424, p = 0.005). Bachelor's holders showed lower odds of high AI practice (AOR = 0.388, p = 0.017).

Conclusion: Despite moderate perception, most professionals have knowledge, attitude, and practice defects. Mainly, younger age and men showed higher engagement, indicating a need for targeted AI training, especially for older and female professionals.

背景:医疗保健专业人员对医疗保健中人工智能应用的认识和处理可以提高患者的治疗效果并改善流程。本研究旨在评估埃及医疗保健专业人员对人工智能应用的看法、态度、知识和实践。方法:一项横断面研究,其中367名医疗保健专业人员回答了一份电子问卷。结果:在367名参与者中(234名女性),放射学和实验室检测专业占36.2%。平均年龄27.03 岁;51.8%的受访者对人工智能工具持积极态度,68.7%的受访者认为知识不够理想,52.9%的受访者持消极态度,53.4%的受访者表示人工智能工具的实践水平较低。年龄越小,积极感知能力越强(调整优势比(AOR) = 0.905,p = 0.020),人工智能水平越高(AOR = 0.907,p = 0.026)。大学医院专业人员获得最佳知识的几率比私立医院专业人员低61.4% (AOR = 0.386,p = 0.046)。男性有更高的几率都积极的态度(AOR = 1.844,p = 0.010)和高实践水平(AOR = 2.92,p  = 0.036),以及医生比护士和其他(AOR = 0.424,p = 0.005)。学士学位持有者的高人工智能实践的几率较低(AOR = 0.388,p = 0.017)。结论:大多数专业人员在认知上存在一定的缺陷,但在知识、态度和实践上存在一定的缺陷。主要是年轻人和男性表现出更高的参与度,这表明需要有针对性的人工智能培训,尤其是对老年人和女性专业人士。
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